psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I11	R:R:V169	4.61	No	No	0	3	5
2	R:R:I14	R:R:K12	5.82	No	No	7	3	4
3	R:R:F170	R:R:K12	6.2	No	No	7	3	4
4	R:R:F171	R:R:R13	8.55	No	No	0	6	4
5	R:R:E173	R:R:R13	4.65	No	No	0	3	4
6	R:R:F170	R:R:I14	10.05	No	No	7	3	3
7	R:R:H183	R:R:I14	13.26	Yes	No	7	3	3
8	R:R:E173	R:R:Q15	7.65	No	No	8	3	4
9	R:R:N174	R:R:Q15	3.96	No	No	8	3	4
10	R:R:D16	R:R:P19	6.44	No	Yes	0	4	4
11	L:L:V3	R:R:D16	5.84	No	No	0	0	4
12	L:L:?1	R:R:D17	4.21	No	No	0	0	6
13	R:R:C18	R:R:C274	7.28	No	No	0	8	7
14	R:R:A21	R:R:D281	4.63	No	No	0	4	4
15	R:R:R23	R:R:Y92	7.2	No	Yes	3	4	4
16	L:L:I5	R:R:R23	3.76	Yes	No	3	0	4
17	R:R:H24	R:R:Y26	10.89	Yes	No	5	4	6
18	R:R:H24	R:R:I27	5.3	Yes	No	5	4	3
19	R:R:D278	R:R:H24	7.56	No	Yes	5	4	4
20	R:R:H24	R:R:T282	5.48	Yes	No	5	4	1
21	R:R:I27	R:R:Y26	7.25	No	No	5	3	6
22	R:R:E91	R:R:F28	16.32	No	No	0	3	4
23	R:R:F28	R:R:Y92	4.13	No	Yes	0	4	4
24	R:R:I31	R:R:P32	3.39	Yes	No	0	6	5
25	R:R:I31	R:R:Y35	6.04	Yes	Yes	0	6	7
26	R:R:I31	R:R:P285	5.08	Yes	No	0	6	5
27	R:R:A89	R:R:P32	3.74	No	No	0	3	5
28	R:R:C289	R:R:L34	6.35	No	No	0	5	5
29	R:R:L81	R:R:Y35	8.21	Yes	Yes	0	8	7
30	R:R:I288	R:R:Y35	6.04	No	Yes	0	6	7
31	R:R:C289	R:R:Y35	4.03	No	Yes	0	5	7
32	R:R:F39	R:R:I43	5.02	No	No	0	6	6
33	R:R:F39	R:R:L81	3.65	No	Yes	0	6	8
34	R:R:F39	R:R:P82	14.45	No	No	0	6	9
35	R:R:D74	R:R:N46	6.73	Yes	No	0	9	9
36	R:R:N46	R:R:P299	11.4	No	No	0	9	9
37	R:R:F304	R:R:L48	3.65	No	No	0	6	6
38	R:R:F313	R:R:L48	6.09	No	No	0	7	6
39	R:R:P299	R:R:V49	3.53	No	Yes	0	9	9
40	R:R:F55	R:R:I51	3.77	No	No	0	4	3
41	R:R:F309	R:R:V52	3.93	Yes	No	4	8	7
42	R:R:V52	R:R:Y312	3.79	No	Yes	4	7	5
43	R:R:I53	R:R:L68	4.28	No	No	0	7	5
44	R:R:F55	R:R:Y54	7.22	No	No	0	4	4
45	R:R:Y312	R:R:Y56	10.92	Yes	Yes	4	5	4
46	R:R:Q315	R:R:Y56	7.89	No	Yes	4	3	4
47	R:R:L316	R:R:Y56	8.21	No	Yes	0	4	4
48	R:R:Y319	R:R:Y56	3.97	No	Yes	0	5	4
49	R:R:M57	R:R:S64	7.67	No	No	0	5	8
50	R:R:K58	R:R:K60	5.75	No	No	0	5	7
51	R:R:L59	R:R:L68	5.54	No	No	0	7	5
52	R:R:S64	R:R:T61	4.8	No	No	0	8	8
53	R:R:A145	R:R:V65	5.09	No	Yes	0	7	6
54	R:R:K146	R:R:V65	4.55	No	Yes	0	3	6
55	R:R:C121	R:R:F66	4.19	No	Yes	0	7	7
56	R:R:F66	R:R:L122	3.65	Yes	No	0	7	9
57	R:R:D125	R:R:F66	9.55	No	Yes	0	8	7
58	R:R:F66	R:R:T148	5.19	Yes	No	0	7	5
59	R:R:L118	R:R:N69	4.12	No	No	0	7	9
60	R:R:C149	R:R:N69	7.87	No	No	0	7	9
61	R:R:N69	R:R:W153	6.78	No	Yes	0	9	9
62	R:R:D74	R:R:L70	4.07	Yes	Yes	6	9	9
63	R:R:L119	R:R:L70	5.54	No	Yes	6	8	9
64	R:R:L70	R:R:N298	4.12	Yes	No	6	9	9
65	R:R:L70	R:R:Y302	3.52	Yes	Yes	6	9	9
66	R:R:D74	R:R:S115	5.89	Yes	No	0	9	9
67	R:R:A295	R:R:D74	4.63	No	Yes	0	9	9
68	R:R:D74	R:R:N298	6.73	Yes	No	6	9	9
69	R:R:C76	R:R:N111	6.3	No	No	0	7	8
70	R:R:L83	R:R:T80	4.42	No	No	0	6	7
71	R:R:T80	R:R:W84	4.85	No	Yes	0	7	7
72	R:R:S107	R:R:T80	6.4	No	No	0	5	7
73	R:R:L81	R:R:Y292	8.21	Yes	No	0	8	7
74	R:R:F96	R:R:L83	4.87	Yes	No	0	6	6
75	R:R:W84	R:R:Y87	3.86	Yes	Yes	0	7	5
76	R:R:A104	R:R:W84	3.89	No	Yes	0	6	7
77	L:L:P7	R:R:W84	16.21	No	Yes	0	0	7
78	R:R:Y87	R:R:Y92	10.92	Yes	Yes	3	5	4
79	R:R:W94	R:R:Y87	10.61	Yes	Yes	3	9	5
80	L:L:I5	R:R:Y87	4.84	Yes	Yes	3	0	5
81	R:R:T88	R:R:Y92	7.49	No	Yes	0	5	4
82	R:R:M90	R:R:P95	3.35	No	No	0	5	3
83	R:R:E91	R:R:R93	10.47	No	No	0	3	5
84	L:L:I5	R:R:Y92	8.46	Yes	Yes	3	0	4
85	R:R:I177	R:R:R93	5.01	No	No	0	1	5
86	R:R:F96	R:R:W94	17.04	Yes	Yes	0	6	9
87	R:R:C101	R:R:W94	9.14	No	Yes	3	9	9
88	R:R:C180	R:R:W94	15.67	No	Yes	3	9	9
89	R:R:F96	R:R:P95	7.22	Yes	No	0	6	3
90	R:R:F96	R:R:L100	6.09	Yes	No	0	6	5
91	R:R:K102	R:R:N98	8.39	No	No	0	6	3
92	R:R:N168	R:R:N98	6.81	No	No	0	3	3
93	R:R:N98	R:R:V169	5.91	No	No	0	3	5
94	R:R:C101	R:R:C180	7.28	No	No	3	9	9
95	R:R:R167	R:R:S105	15.81	No	No	0	5	5
96	R:R:A106	R:R:I164	4.87	No	No	0	5	5
97	R:R:V108	R:R:Y292	3.79	No	No	0	6	7
98	L:L:F8	R:R:V108	3.93	Yes	No	0	0	6
99	R:R:S109	R:R:S160	6.52	No	No	0	4	7
100	R:R:A163	R:R:S109	3.42	No	No	0	4	4
101	L:L:F8	R:R:S109	5.28	Yes	No	0	0	4
102	R:R:F110	R:R:N111	4.83	Yes	No	0	5	8
103	R:R:F110	R:R:W153	7.02	Yes	Yes	0	5	9
104	R:R:L112	R:R:W253	3.42	No	Yes	0	7	8
105	R:R:L112	R:R:Y292	7.03	No	No	0	7	7
106	L:L:F8	R:R:L112	4.87	Yes	No	0	0	7
107	R:R:F117	R:R:Y113	6.19	No	Yes	0	5	7
108	R:R:A159	R:R:Y113	8.01	No	Yes	0	5	7
109	R:R:T198	R:R:Y113	4.99	No	Yes	0	3	7
110	R:R:K199	R:R:Y113	4.78	Yes	Yes	2	5	7
111	L:L:F8	R:R:Y113	4.13	Yes	Yes	2	0	7
112	R:R:A114	R:R:W153	6.48	No	Yes	0	7	9
113	R:R:P207	R:R:V116	3.53	Yes	No	0	8	8
114	R:R:V116	R:R:W253	4.9	No	Yes	0	8	8
115	R:R:F117	R:R:L155	3.65	No	No	0	5	4
116	R:R:L119	R:R:Y302	5.86	No	Yes	6	8	9
117	R:R:P207	R:R:T120	3.5	Yes	No	0	8	7
118	R:R:I210	R:R:T120	6.08	No	No	0	7	7
119	R:R:I211	R:R:S123	4.64	No	No	0	8	9
120	R:R:S123	R:R:S214	4.89	No	No	0	9	7
121	R:R:S123	R:R:Y215	5.09	No	Yes	0	9	9
122	R:R:D125	R:R:R140	10.72	No	Yes	0	8	6
123	R:R:R126	R:R:Y215	8.23	No	Yes	0	9	9
124	R:R:R126	R:R:Y302	7.2	No	Yes	0	9	9
125	R:R:L128	R:R:Y127	3.52	No	Yes	0	5	8
126	R:R:V131	R:R:Y127	11.36	No	Yes	1	7	8
127	R:R:H132	R:R:Y127	8.71	No	Yes	1	6	8
128	R:R:L217	R:R:Y127	8.21	No	Yes	0	3	8
129	R:R:I218	R:R:Y127	3.63	No	Yes	1	8	8
130	R:R:L128	R:R:R140	3.64	No	Yes	0	5	6
131	R:R:A129	R:R:R140	5.53	No	Yes	0	8	6
132	R:R:I130	R:R:I218	4.42	No	No	1	8	8
133	R:R:H132	R:R:V131	11.07	No	No	1	6	7
134	R:R:A221	R:R:V131	5.09	No	No	0	5	7
135	R:R:R140	R:R:S136	6.59	Yes	No	0	6	6
136	R:R:H166	R:R:P192	4.58	No	No	0	4	3
137	R:R:F182	R:R:R167	17.1	Yes	No	0	4	5
138	R:R:C180	R:R:V169	5.12	No	No	0	9	5
139	R:R:F170	R:R:H183	3.39	No	Yes	7	3	3
140	R:R:F171	R:R:N176	3.62	No	No	0	6	5
141	R:R:E173	R:R:N174	3.94	No	No	8	3	3
142	R:R:I177	R:R:T175	9.12	No	No	0	1	2
143	R:R:F182	R:R:Y184	4.13	Yes	Yes	2	4	4
144	R:R:F182	R:R:L195	4.87	Yes	No	0	4	5
145	L:L:Y4	R:R:F182	6.19	Yes	Yes	2	0	4
146	R:R:E185	R:R:H183	4.92	No	Yes	0	5	3
147	L:L:?1	R:R:H183	14.62	No	Yes	0	0	3
148	R:R:P192	R:R:Y184	4.17	No	Yes	0	3	4
149	R:R:Q267	R:R:Y184	12.4	No	Yes	0	3	4
150	L:L:R2	R:R:Y184	5.14	Yes	Yes	0	0	4
151	L:L:Y4	R:R:Y184	6.95	Yes	Yes	2	0	4
152	R:R:E185	R:R:S189	4.31	No	No	0	5	2
153	R:R:N188	R:R:Q187	13.2	No	No	0	3	1
154	R:R:P192	R:R:S189	8.91	No	No	0	3	2
155	R:R:Q267	R:R:S189	5.78	No	No	0	3	2
156	R:R:I193	R:R:Q267	6.86	No	No	0	2	3
157	R:R:H256	R:R:K199	7.86	Yes	Yes	2	6	5
158	R:R:K199	R:R:T260	10.51	Yes	No	2	5	6
159	L:L:F8	R:R:K199	23.58	Yes	Yes	2	0	5
160	R:R:N200	R:R:Q257	3.96	No	No	0	4	8
161	R:R:F261	R:R:N200	3.62	No	No	0	5	4
162	R:R:G203	R:R:P207	4.06	No	Yes	0	5	8
163	R:R:F204	R:R:F250	6.43	Yes	Yes	9	8	5
164	R:R:F204	R:R:I254	3.77	Yes	Yes	9	8	5
165	R:R:F204	R:R:Q257	10.54	Yes	No	0	8	8
166	R:R:F208	R:R:L212	6.09	No	No	0	6	5
167	R:R:F208	R:R:F250	9.65	No	Yes	0	6	5
168	R:R:F249	R:R:I211	5.02	No	No	0	9	8
169	R:R:I242	R:R:Y215	3.63	No	Yes	0	7	9
170	R:R:I245	R:R:Y215	4.84	No	Yes	0	8	9
171	R:R:V246	R:R:Y215	5.05	No	Yes	0	8	9
172	R:R:K223	R:R:W219	3.48	No	Yes	1	5	5
173	R:R:F239	R:R:W219	10.02	Yes	Yes	1	6	5
174	R:R:I242	R:R:W219	5.87	No	Yes	0	7	5
175	R:R:M243	R:R:W219	4.65	No	Yes	0	4	5
176	R:R:F239	R:R:L222	4.87	Yes	No	1	6	8
177	R:R:F239	R:R:K223	8.69	Yes	No	1	6	5
178	R:R:P233	R:R:Y226	5.56	No	Yes	1	3	4
179	R:R:N235	R:R:Y226	6.98	No	Yes	1	6	4
180	R:R:I238	R:R:Y226	4.84	No	Yes	0	7	4
181	R:R:K232	R:R:R234	3.71	No	No	0	3	5
182	R:R:N235	R:R:P233	6.52	No	No	1	6	3
183	R:R:F239	R:R:N235	6.04	Yes	No	1	6	6
184	R:R:D236	R:R:D237	10.65	No	No	0	4	7
185	R:R:F239	R:R:I238	3.77	Yes	No	0	6	7
186	R:R:I241	R:R:L305	4.28	No	No	0	8	7
187	R:R:I245	R:R:Y302	8.46	No	Yes	0	8	9
188	R:R:F248	R:R:S252	3.96	Yes	No	10	6	8
189	R:R:F248	R:R:N294	6.04	Yes	No	10	6	9
190	R:R:F248	R:R:L297	7.31	Yes	No	0	6	6
191	R:R:F248	R:R:F301	11.79	Yes	No	0	6	8
192	R:R:F249	R:R:W253	5.01	No	Yes	0	9	8
193	R:R:F250	R:R:F251	10.72	Yes	No	0	5	6
194	R:R:F250	R:R:I254	7.54	Yes	Yes	9	5	5
195	R:R:N294	R:R:S252	8.94	No	No	10	9	8
196	R:R:N294	R:R:W253	7.91	No	Yes	0	9	8
197	R:R:I254	R:R:P255	5.08	Yes	No	0	5	9
198	R:R:I254	R:R:I258	4.42	Yes	No	0	5	6
199	R:R:P255	R:R:T287	3.5	No	No	0	9	7
200	R:R:I290	R:R:P255	5.08	No	No	0	8	9
201	R:R:H256	R:R:T260	6.85	Yes	No	2	6	6
202	R:R:H256	R:R:M284	3.94	Yes	No	2	6	4
203	R:R:H256	R:R:T287	8.21	Yes	No	0	6	7
204	R:R:H256	R:R:I288	3.98	Yes	No	0	6	6
205	L:L:F8	R:R:H256	7.92	Yes	Yes	2	0	6
206	R:R:A283	R:R:F259	8.32	No	No	0	5	5
207	R:R:F261	R:R:L265	6.09	No	No	0	5	3
208	L:L:R2	R:R:D263	7.15	Yes	No	0	0	4
209	L:L:Y4	R:R:D263	6.9	Yes	No	0	0	4
210	R:R:I270	R:R:L265	5.71	No	No	0	2	3
211	R:R:I271	R:R:L265	4.28	No	No	0	1	3
212	R:R:I266	R:R:I271	5.89	No	No	0	2	1
213	R:R:I266	R:R:V280	4.61	No	No	0	2	4
214	L:L:R2	R:R:I266	5.01	Yes	No	0	0	2
215	R:R:I271	R:R:I276	4.42	No	No	0	1	1
216	R:R:D273	R:R:R275	4.76	No	No	0	4	2
217	R:R:A277	R:R:C274	3.61	No	No	0	3	7
218	R:R:I276	R:R:I279	4.42	No	No	0	1	1
219	R:R:D278	R:R:T282	4.34	No	No	5	4	1
220	L:L:R2	R:R:D281	10.72	Yes	No	0	0	4
221	L:L:H6	R:R:D281	11.35	Yes	No	0	0	4
222	L:L:Y4	R:R:M284	4.79	Yes	No	2	0	4
223	L:L:H6	R:R:M284	9.19	Yes	No	2	0	4
224	L:L:H6	R:R:P285	7.63	Yes	No	0	0	5
225	L:L:P7	R:R:I288	5.08	No	No	0	0	6
226	R:R:F293	R:R:I290	5.02	No	No	0	5	8
227	R:R:N298	R:R:Y302	3.49	No	Yes	6	9	9
228	R:R:F304	R:R:F309	5.36	No	Yes	0	6	8
229	R:R:K308	R:R:Y312	9.55	No	Yes	0	6	5
230	R:R:F309	R:R:Y312	4.13	Yes	Yes	4	8	5
231	R:R:R311	R:R:Y312	11.32	No	Yes	4	5	5
232	R:R:Q315	R:R:R311	8.18	No	No	4	3	5
233	R:R:Q315	R:R:Y312	4.51	No	Yes	4	3	5
234	L:L:?1	L:L:V3	4.62	No	No	0	0	0
235	L:L:H6	L:L:Y4	11.98	Yes	Yes	2	0	0
236	R:R:L161	R:R:P162	3.28	No	No	0	4	6
237	R:R:C121	R:R:I152	3.27	No	No	0	7	7
238	R:R:N174	R:R:P19	3.26	No	Yes	0	3	4
239	L:L:I5	R:R:A181	3.25	Yes	No	0	0	5
240	R:R:T141	R:R:V144	3.17	No	No	0	7	4
241	R:R:F55	R:R:Y56	3.09	No	Yes	0	4	4
242	R:R:I53	R:R:V49	3.07	No	Yes	0	7	9
243	R:R:I151	R:R:V147	3.07	No	No	0	3	3
244	R:R:I172	R:R:V179	3.07	No	No	0	5	3
245	L:L:I5	R:R:V179	3.07	Yes	No	0	0	3
246	R:R:F110	R:R:G157	3.01	Yes	No	0	5	3
247	R:R:F309	R:R:G303	3.01	Yes	No	0	8	7
248	R:R:L59	R:R:S64	3	No	No	0	7	8
249	R:R:L262	R:R:V280	2.98	No	No	0	5	4
250	R:R:L202	R:R:T198	2.95	No	No	0	4	3
251	R:R:L212	R:R:T216	2.95	No	No	0	5	3
252	R:R:I27	R:R:I31	2.94	No	Yes	0	3	6
253	R:R:I286	R:R:I31	2.94	No	Yes	0	6	6
254	R:R:I124	R:R:I210	2.94	No	No	0	6	7
255	R:R:I164	R:R:I165	2.94	No	No	0	5	4
256	R:R:I241	R:R:I245	2.94	No	No	0	8	8
257	R:R:I31	R:R:M30	2.92	Yes	No	0	6	4
258	R:R:E185	R:R:S186	2.87	No	No	0	5	3
259	R:R:I38	R:R:L81	2.85	No	Yes	0	7	8
260	R:R:I43	R:R:L75	2.85	No	No	0	6	7
261	R:R:I152	R:R:L118	2.85	No	No	0	7	7
262	R:R:I130	R:R:L222	2.85	No	No	1	8	8
263	R:R:I218	R:R:L222	2.85	No	No	1	8	8
264	R:R:L247	R:R:M243	2.83	No	No	0	5	4
265	R:R:G97	R:R:W94	2.81	No	Yes	0	8	9
266	R:R:L122	R:R:L67	2.77	No	No	0	9	8
267	R:R:L68	R:R:L72	2.77	No	No	0	5	5
268	R:R:A156	R:R:F110	2.77	No	Yes	0	8	5
269	R:R:A156	R:R:F117	2.77	No	No	0	8	5
270	R:R:D236	R:R:K240	2.77	No	No	0	4	5
271	R:R:A244	R:R:F301	2.77	No	No	0	5	8
272	R:R:L300	R:R:L305	2.77	No	No	0	6	7
273	R:R:A85	R:R:Y35	2.67	No	Yes	0	7	7
274	R:R:F304	R:R:V49	2.62	No	Yes	0	6	9
275	R:R:F66	R:R:V62	2.62	Yes	No	0	7	7
276	R:R:R140	R:R:V62	2.62	Yes	No	0	6	7
277	R:R:F96	R:R:V86	2.62	Yes	No	0	6	4
278	R:R:A73	R:R:W153	2.59	No	Yes	0	8	9
279	R:R:F171	R:R:T178	2.59	No	No	0	6	4
280	R:R:F259	R:R:T287	2.59	No	No	0	5	7
281	R:R:H166	R:R:L191	2.57	No	No	0	4	1
282	R:R:I276	R:R:R275	2.51	No	No	0	1	2
283	R:R:F204	R:R:L205	2.44	Yes	No	0	8	4
284	R:R:K220	R:R:W219	2.32	No	Yes	0	3	5
285	R:R:G45	R:R:P299	2.03	No	No	0	7	9
286	R:R:C296	R:R:G42	1.96	No	Yes	0	8	8
287	R:R:C18	R:R:P19	1.88	No	Yes	0	8	4
288	R:R:G42	R:R:V41	1.84	Yes	No	0	8	5
289	R:R:G196	R:R:V264	1.84	No	No	0	5	4
290	R:R:G22	R:R:T282	1.82	No	No	0	2	1
291	R:R:G42	R:R:L78	1.71	Yes	No	0	8	6
292	R:R:C149	R:R:V65	1.71	No	Yes	0	7	6
293	R:R:A106	R:R:S160	1.71	No	No	0	5	7
294	R:R:G196	R:R:L195	1.71	No	No	0	5	5
295	R:R:G42	R:R:N46	1.7	Yes	No	0	8	9
296	R:R:A71	R:R:V49	1.7	No	Yes	0	8	9
297	R:R:A71	R:R:V50	1.7	No	No	0	8	7
298	R:R:A63	R:R:T61	1.68	No	No	0	7	8
299	R:R:K20	R:R:P19	1.67	No	Yes	0	6	4
300	R:R:L195	R:R:P162	1.64	No	No	0	5	6
301	R:R:T148	R:R:V144	1.59	No	No	0	5	4
302	R:R:A77	R:R:N111	1.56	No	No	0	6	8
303	R:R:I37	R:R:S36	1.55	No	No	0	5	5
304	R:R:I43	R:R:S47	1.55	No	No	0	6	3
305	R:R:I37	R:R:V41	1.54	No	No	0	5	5
306	R:R:H132	R:R:P133	1.53	No	No	0	6	8
307	R:R:I37	R:R:T33	1.52	No	No	0	5	6
308	R:R:M142	R:R:V62	1.52	No	No	0	1	7
309	R:R:M142	R:R:V65	1.52	No	Yes	0	1	6
310	R:R:F44	R:R:G45	1.51	No	No	0	4	7
311	R:R:L143	R:R:V147	1.49	No	No	0	4	3
312	R:R:N188	R:R:S186	1.49	No	No	0	3	3
313	R:R:L268	R:R:V264	1.49	No	No	0	1	4
314	R:R:L143	R:R:T141	1.47	No	No	0	4	7
315	R:R:I150	R:R:I151	1.47	No	No	0	4	3
316	R:R:L217	R:R:T213	1.47	No	No	0	3	4
317	R:R:I228	R:R:K224	1.45	No	No	0	2	4
318	R:R:F206	R:R:P207	1.44	No	Yes	0	6	8
319	R:R:K318	R:R:L314	1.41	No	No	0	3	3
320	R:R:L314	R:R:L317	1.38	No	No	0	3	6
321	R:R:E227	R:R:I228	1.37	No	No	0	4	2
322	R:R:I228	R:R:Q229	1.37	No	No	0	2	3
323	R:R:A225	R:R:Y226	1.33	No	Yes	0	6	4
324	R:R:N231	R:R:Q229	1.32	No	No	0	4	3
325	R:R:M134	R:R:R137	1.24	No	No	0	6	4
326	R:R:L128	R:R:R139	1.21	No	No	0	5	4
327	R:R:L138	R:R:R139	1.21	No	No	0	4	4
328	R:R:D236	R:R:R234	1.19	No	No	0	4	5
329	R:R:K318	R:R:Y319	1.19	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:P19	3.3125	4	0	4
2	R:R:H24	7.3075	4	5	4
3	R:R:I31	3.885	6	0	6
4	R:R:Y35	5.398	5	0	7
5	R:R:G42	1.8025	4	0	8
6	R:R:V49	2.73	4	0	9
7	R:R:Y56	6.816	5	4	4
8	R:R:V65	3.2175	4	0	6
9	R:R:F66	5.04	5	0	7
10	R:R:L70	4.3125	4	6	9
11	R:R:D74	5.61	5	6	9
12	R:R:L81	5.73	4	0	8
13	R:R:W84	7.2025	4	0	7
14	R:R:Y87	7.5575	4	3	5
15	R:R:Y92	7.64	5	3	4
16	R:R:W94	11.054	5	3	9
17	R:R:F96	7.568	5	0	6
18	R:R:F110	4.4075	4	0	5
19	R:R:Y113	5.62	5	2	7
20	R:R:Y127	7.086	5	1	8
21	R:R:R140	5.82	5	0	6
22	R:R:W153	5.7175	4	0	9
23	R:R:F182	8.0725	4	2	4
24	R:R:H183	9.0475	4	7	3
25	R:R:Y184	6.558	5	2	4
26	R:R:K199	11.6825	4	2	5
27	R:R:F204	5.795	4	9	8
28	R:R:P207	3.1325	4	0	8
29	R:R:Y215	5.368	5	0	9
30	R:R:W219	5.268	5	1	5
31	R:R:Y226	4.6775	4	1	4
32	R:R:F239	6.678	5	1	6
33	R:R:F248	7.275	4	10	6
34	R:R:F250	8.585	4	9	5
35	R:R:W253	5.31	4	0	8
36	R:R:I254	5.2025	4	9	5
37	R:R:H256	6.46	6	2	6
38	R:R:Y302	5.706	5	6	9
39	R:R:F309	4.1075	4	4	8
40	R:R:Y312	7.37	6	4	5
41	L:L:R2	7.005	4	0	0
42	L:L:Y4	7.362	5	2	0
43	L:L:I5	4.676	5	3	0
44	L:L:H6	10.0375	4	2	0
45	L:L:F8	8.285	6	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:W94	R:R:Y87	13.5925	10.61	Yes	Yes	3	9	5
2	R:R:W84	R:R:Y87	26.2829	3.86	Yes	Yes	0	7	5
3	L:L:P7	R:R:W84	35.4097	16.21	No	Yes	0	0	7
4	L:L:P7	R:R:I288	36.2688	5.08	No	No	0	0	6
5	R:R:H256	R:R:I288	40.2991	3.98	Yes	No	0	6	6
6	R:R:H256	R:R:M284	81.1568	3.94	Yes	No	2	6	4
7	L:L:Y4	R:R:M284	69.5579	4.79	Yes	No	2	0	4
8	L:L:Y4	R:R:Y184	56.1255	6.95	Yes	Yes	2	0	4
9	R:R:P192	R:R:Y184	25.5487	4.17	No	Yes	0	3	4
10	R:R:P192	R:R:S189	23.059	8.91	No	No	0	3	2
11	R:R:E185	R:R:S189	44.3236	4.31	No	No	0	5	2
12	R:R:E185	R:R:H183	37.3955	4.92	No	Yes	0	5	3
13	R:R:Q267	R:R:Y184	24.668	12.4	No	Yes	0	3	4
14	R:R:Q267	R:R:S189	23.0083	5.78	No	No	0	3	2
15	R:R:N174	R:R:P19	12.6552	3.26	No	Yes	0	3	4
16	R:R:D16	R:R:P19	21.5789	6.44	No	Yes	0	4	4
17	L:L:V3	R:R:D16	23.3519	5.84	No	No	0	0	4
18	L:L:?1	L:L:V3	25.1211	4.62	No	No	0	0	0
19	L:L:?1	R:R:H183	28.6476	14.62	No	Yes	0	0	3
20	L:L:H6	R:R:D281	10.3257	11.35	Yes	No	0	0	4
21	L:L:H6	R:R:M284	11.0443	9.19	Yes	No	2	0	4
22	R:R:I31	R:R:Y35	11.0033	6.04	Yes	Yes	0	6	7
23	R:R:L81	R:R:Y35	10.7221	8.21	Yes	Yes	0	8	7
24	R:R:D74	R:R:L70	52.556	4.07	Yes	Yes	6	9	9
25	R:R:L70	R:R:Y302	53.5792	3.52	Yes	Yes	6	9	9
26	R:R:R126	R:R:Y302	54.3584	7.2	No	Yes	0	9	9
27	R:R:R126	R:R:Y215	54.7626	8.23	No	Yes	0	9	9
28	R:R:S123	R:R:Y215	99.6973	5.09	No	Yes	0	9	9
29	R:R:I211	R:R:S123	99.6466	4.64	No	No	0	8	9
30	R:R:F249	R:R:I211	99.6329	5.02	No	No	0	9	8
31	R:R:F249	R:R:W253	99.6427	5.01	No	Yes	0	9	8
32	R:R:L112	R:R:W253	100	3.42	No	Yes	0	7	8
33	L:L:F8	R:R:L112	89.4341	4.87	Yes	No	0	0	7
34	L:L:F8	R:R:H256	94.1361	7.92	Yes	Yes	2	0	6
35	R:R:D74	R:R:N298	52.4545	6.73	Yes	No	6	9	9
36	R:R:N298	R:R:Y302	53.5656	3.49	No	Yes	6	9	9
37	R:R:I245	R:R:Y302	54.9266	8.46	No	Yes	0	8	9
38	R:R:I245	R:R:Y215	56.559	4.84	No	Yes	0	8	9
39	R:R:D74	R:R:N46	98.0649	6.73	Yes	No	0	9	9
40	R:R:N46	R:R:P299	79.3662	11.4	No	No	0	9	9
41	R:R:F304	R:R:V49	46.0322	2.62	No	Yes	0	6	9
42	R:R:P299	R:R:V49	72.2897	3.53	No	Yes	0	9	9
43	R:R:Y312	R:R:Y56	21.8367	10.92	Yes	Yes	4	5	4
44	R:R:F309	R:R:Y312	31.5903	4.13	Yes	Yes	4	8	5
45	R:R:F304	R:R:F309	38.8874	5.36	No	Yes	0	6	8
46	R:R:I53	R:R:V49	19.7278	3.07	No	Yes	0	7	9
47	R:R:I53	R:R:L68	17.2752	4.28	No	No	0	7	5
48	R:R:L59	R:R:L68	12.3584	5.54	No	No	0	7	5
49	R:R:C149	R:R:N69	10.0543	7.87	No	No	0	7	9
50	R:R:N69	R:R:W153	23.0005	6.78	No	Yes	0	9	9
51	R:R:F110	R:R:W153	26.2868	7.02	Yes	Yes	0	5	9
52	R:R:A156	R:R:F110	31.7738	2.77	No	Yes	0	8	5
53	R:R:A156	R:R:F117	32.8927	2.77	No	No	0	8	5
54	R:R:F117	R:R:Y113	35.1304	6.19	No	Yes	0	5	7
55	R:R:K199	R:R:Y113	15.0141	4.78	Yes	Yes	2	5	7
56	R:R:H256	R:R:K199	15.1898	7.86	Yes	Yes	2	6	5
57	L:L:F8	R:R:Y113	24.5665	4.13	Yes	Yes	2	0	7
58	R:R:C121	R:R:I152	11.6281	3.27	No	No	0	7	7
59	R:R:I152	R:R:L118	11.5656	2.85	No	No	0	7	7
60	R:R:L118	R:R:N69	11.8839	4.12	No	No	0	7	9
61	R:R:C121	R:R:F66	11.7062	4.19	No	Yes	0	7	7
62	R:R:F66	R:R:T148	11.9757	5.19	Yes	No	0	7	5
63	R:R:L81	R:R:Y292	12.1163	8.21	Yes	No	0	8	7
64	R:R:R140	R:R:V62	13.3348	2.62	Yes	No	0	6	7
65	R:R:L128	R:R:R140	18.2809	3.64	No	Yes	0	5	6
66	R:R:I242	R:R:Y215	34.4665	3.63	No	Yes	0	7	9
67	R:R:I242	R:R:W219	33.7909	5.87	No	Yes	0	7	5
68	R:R:F239	R:R:W219	30.1004	10.02	Yes	Yes	1	6	5
69	R:R:F239	R:R:L222	24.5392	4.87	Yes	No	1	6	8
70	R:R:I218	R:R:L222	23.0102	2.85	No	No	1	8	8
71	R:R:I218	R:R:Y127	22.3951	3.63	No	Yes	1	8	8
72	L:L:R2	R:R:Y184	10.3081	5.14	Yes	Yes	0	0	4
73	R:R:H256	R:R:T287	16.254	8.21	Yes	No	0	6	7
74	R:R:P255	R:R:T287	13.4597	3.5	No	No	0	9	7
75	R:R:I254	R:R:P255	10.7475	5.08	Yes	No	0	5	9
76	L:L:R2	R:R:I266	24.4122	5.01	Yes	No	0	0	2
77	R:R:I266	R:R:I271	17.3065	5.89	No	No	0	2	1
78	R:R:T148	R:R:V144	10.355	1.59	No	No	0	5	4
79	R:R:G42	R:R:N46	17.2752	1.7	Yes	No	0	8	9
80	R:R:L112	R:R:Y292	12.5381	7.03	No	No	0	7	7
81	R:R:L128	R:R:Y127	17.3026	3.52	No	Yes	0	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F170	R:R:I14	10.05	7	No	No	3	3	2	2
R:R:H183	R:R:I14	13.26	7	Yes	No	3	3	1	2
R:R:D16	R:R:P19	6.44	0	No	Yes	4	4	1	2
L:L:V3	R:R:D16	5.84	0	No	No	0	4	0	1
L:L:?1	R:R:D17	4.21	0	No	No	0	6	0	1
R:R:A21	R:R:D281	4.63	0	No	No	4	4	2	1
R:R:R23	R:R:Y92	7.2	3	No	Yes	4	4	1	1
L:L:I5	R:R:R23	3.76	3	Yes	No	0	4	0	1
R:R:F28	R:R:Y92	4.13	0	No	Yes	4	4	2	1
R:R:I31	R:R:Y35	6.04	0	Yes	Yes	6	7	2	2
R:R:I31	R:R:P285	5.08	0	Yes	No	6	5	2	1
R:R:I288	R:R:Y35	6.04	0	No	Yes	6	7	1	2
R:R:T80	R:R:W84	4.85	0	No	Yes	7	7	2	1
R:R:W84	R:R:Y87	3.86	0	Yes	Yes	7	5	1	1
R:R:A104	R:R:W84	3.89	0	No	Yes	6	7	2	1
L:L:P7	R:R:W84	16.21	0	No	Yes	0	7	0	1
R:R:Y87	R:R:Y92	10.92	3	Yes	Yes	5	4	1	1
R:R:W94	R:R:Y87	10.61	3	Yes	Yes	9	5	2	1
L:L:I5	R:R:Y87	4.84	3	Yes	Yes	0	5	0	1
R:R:T88	R:R:Y92	7.49	0	No	Yes	5	4	2	1
L:L:I5	R:R:Y92	8.46	3	Yes	Yes	0	4	0	1
R:R:V108	R:R:Y292	3.79	0	No	No	6	7	1	2
L:L:F8	R:R:V108	3.93	2	Yes	No	0	6	0	1
R:R:S109	R:R:S160	6.52	0	No	No	4	7	1	2
R:R:A163	R:R:S109	3.42	0	No	No	4	4	2	1
L:L:F8	R:R:S109	5.28	2	Yes	No	0	4	0	1
R:R:L112	R:R:W253	3.42	0	No	Yes	7	8	1	2
R:R:L112	R:R:Y292	7.03	0	No	No	7	7	1	2
L:L:F8	R:R:L112	4.87	2	Yes	No	0	7	0	1
R:R:F117	R:R:Y113	6.19	0	No	Yes	5	7	2	1
R:R:A159	R:R:Y113	8.01	0	No	Yes	5	7	2	1
R:R:T198	R:R:Y113	4.99	0	No	Yes	3	7	2	1
R:R:K199	R:R:Y113	4.78	2	Yes	Yes	5	7	1	1
L:L:F8	R:R:Y113	4.13	2	Yes	Yes	0	7	0	1
R:R:F182	R:R:R167	17.1	2	Yes	No	4	5	1	2
R:R:F170	R:R:H183	3.39	7	No	Yes	3	3	2	1
R:R:F182	R:R:Y184	4.13	2	Yes	Yes	4	4	1	1
R:R:F182	R:R:L195	4.87	2	Yes	No	4	5	1	2
L:L:Y4	R:R:F182	6.19	2	Yes	Yes	0	4	0	1
R:R:E185	R:R:H183	4.92	0	No	Yes	5	3	2	1
L:L:?1	R:R:H183	14.62	0	No	Yes	0	3	0	1
R:R:P192	R:R:Y184	4.17	0	No	Yes	3	4	2	1
R:R:Q267	R:R:Y184	12.4	0	No	Yes	3	4	2	1
L:L:R2	R:R:Y184	5.14	0	Yes	Yes	0	4	0	1
L:L:Y4	R:R:Y184	6.95	2	Yes	Yes	0	4	0	1
R:R:H256	R:R:K199	7.86	2	Yes	Yes	6	5	1	1
R:R:K199	R:R:T260	10.51	2	Yes	No	5	6	1	2
L:L:F8	R:R:K199	23.58	2	Yes	Yes	0	5	0	1
R:R:H256	R:R:T260	6.85	2	Yes	No	6	6	1	2
R:R:H256	R:R:M284	3.94	2	Yes	No	6	4	1	1
R:R:H256	R:R:T287	8.21	2	Yes	No	6	7	1	2
R:R:H256	R:R:I288	3.98	2	Yes	No	6	6	1	1
L:L:F8	R:R:H256	7.92	2	Yes	Yes	0	6	0	1
L:L:R2	R:R:D263	7.15	0	Yes	No	0	4	0	1
L:L:Y4	R:R:D263	6.9	2	Yes	No	0	4	0	1
R:R:I266	R:R:I271	5.89	0	No	No	2	1	1	2
R:R:I266	R:R:V280	4.61	0	No	No	2	4	1	2
L:L:R2	R:R:I266	5.01	0	Yes	No	0	2	0	1
L:L:R2	R:R:D281	10.72	0	Yes	No	0	4	0	1
L:L:H6	R:R:D281	11.35	2	Yes	No	0	4	0	1
L:L:Y4	R:R:M284	4.79	2	Yes	No	0	4	0	1
L:L:H6	R:R:M284	9.19	2	Yes	No	0	4	0	1
L:L:H6	R:R:P285	7.63	2	Yes	No	0	5	0	1
L:L:P7	R:R:I288	5.08	0	No	No	0	6	0	1
L:L:I5	R:R:A181	3.25	3	Yes	No	0	5	0	1
R:R:I172	R:R:V179	3.07	0	No	No	5	3	2	1
L:L:I5	R:R:V179	3.07	3	Yes	No	0	3	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7F6G_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.35
Number of Linked Nodes	296
Number of Links	329
Number of Hubs	45
Number of Links mediated by Hubs	178
Number of Communities	10
Number of Nodes involved in Communities	58
Number of Links involved in Communities	73

Path Summary
Number Of Nodes in MetaPath	82
Number Of Links MetaPath	81
Number of Shortest Paths	104517
Length Of Smallest Path	3
Average Path Length	18.2904
Length of Longest Path	39
Minimum Path Strength	1.21
Average Path Strength	5.61369
Maximum Path Strength	17.045
Minimum Path Correlation	0.7
Average Path Correlation	0.938603
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	45.8349
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.8259
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SAR
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	SAR
Name	Sarcosine
Synonyms	Sarcosine
Identifier
Formula	C3 H7 N O2
Molecular Weight	89.093
SMILES
PubChem	7311726
Formal Charge	0
Total Atoms	13
Total Chiral Atoms	0
Total Bonds	12
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P30556
Sequence	>7F6G_nogp_Chain_R I K R I Q D D C P K A G R H N Y I F V M I P T L Y S I I F V V G I F G N S L V V I V I Y F Y M K L K T V A S V F L L N L A L A D L C A L L T L P L W A V Y T A M E Y R W P F G N Y L C K I A S A S V S F N L Y A S V F L L T C L S I D R Y L A I V H P M K S R L R R T M L V A K V T C I I I W L L A G L A S L P A I I H R N V F F I E N T N I T V C A F H Y E S Q N S T L P I G L G L T K N I L G F L F P F L I I L T S Y T L I W K A L K K A Y E I Q K N K P R N D D I F K I I M A I V L F F F F S W I P H Q I F T F L D V L I Q L G I I R D C R I A D I V D T A M P I T I C I A Y F N A C L N P L F Y G F L G K K F K R Y F L Q L L K Y I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9EAJ	A	Peptide	Angiotensin	AT₁	Homo sapiens	-	Nanobody AT209	-	3.2	2025-03-05	To be published
	9EAH	A	Peptide	Angiotensin	AT₁	Homo sapiens	Olmesartan	Nanobody AT209	-	3.1	2025-03-05	To be published
	8TH4	A	Peptide	Angiotensin	AT₁	Homo sapiens	Losartan	AT118-L Nanobody	-	3.3	2024-05-22	10.1038/s41589-024-01620-6
	8TH3	A	Peptide	Angiotensin	AT₁	Homo sapiens	-	AT118-H Nanobody	-	3	2024-05-22	10.1038/s41589-024-01620-6
	7F6G	A	Peptide	Angiotensin	AT₁	Homo sapiens	SAR1-AngII	-	Gq/β1/γ2	2.9	2023-03-29	10.15252/embj.2022112940
	7F6G (No Gprot)	A	Peptide	Angiotensin	AT₁	Homo sapiens	SAR1-AngII	-		2.9	2023-03-29	10.15252/embj.2022112940
	9EAI	A	Peptide	Angiotensin	AT₁	Homo sapiens	Losartan	Nanobody AT209	-	3.1	2025-03-05	To be published
	6OS2	A	Peptide	Angiotensin	AT₁	Homo sapiens	TRV026	-	-	2.7	2020-02-19	10.1126/science.aay9813
	6OS1	A	Peptide	Angiotensin	AT₁	Homo sapiens	TRV026	-	-	2.79	2020-02-19	10.1126/science.aay9813
	6OS0	A	Peptide	Angiotensin	AT₁	Homo sapiens	Angiotensinogen	-	-	2.9	2020-02-19	10.1126/science.aay9813
	6DO1	A	Peptide	Angiotensin	AT₁	Homo sapiens	Angiotensin-like peptide S1I8	-	-	2.9	2019-01-30	10.1016/j.cell.2018.12.006
	4ZUD	A	Peptide	Angiotensin	AT₁	Homo sapiens	Olmesartan	-	-	2.8	2015-10-07	10.1074/jbc.M115.689000
	4YAY	A	Peptide	Angiotensin	AT₁	Homo sapiens	ZD-7155	-	-	2.9	2015-04-22	10.1016/j.cell.2015.04.011

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7F6G_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.