psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	H:H:?1	R:R:N25	28.24	No	No	0	0	7
2	H:H:?1	R:R:T35	2.64	No	No	0	0	4
3	H:H:?2	R:R:N32	29.47	No	No	0	0	5
4	H:H:?3	S:S:N25	28.24	No	No	0	0	7
5	H:H:?3	S:S:T35	2.64	No	No	0	0	4
6	H:H:?4	S:S:N32	29.47	No	No	0	0	5
7	R:R:A5	R:R:P6	1.87	No	No	5	2	5
8	R:R:A5	S:S:Y30	4	No	Yes	5	2	7
9	R:R:P6	S:S:Y30	5.56	No	Yes	5	5	7
10	R:R:F12	R:R:L8	7.31	Yes	No	5	1	6
11	R:R:L8	R:R:Y13	2.34	No	No	5	6	2
12	R:R:L8	S:S:Y30	2.34	No	Yes	5	6	7
13	R:R:L11	R:R:S9	4.5	No	No	0	3	7
14	R:R:S9	S:S:G31	3.71	No	No	0	7	8
15	R:R:L11	R:R:Y17	11.72	No	Yes	9	3	7
16	R:R:L11	S:S:F116	2.44	No	Yes	9	3	7
17	R:R:F12	R:R:Y13	7.22	Yes	No	5	1	2
18	R:R:F12	S:S:I29	3.77	Yes	Yes	0	1	4
19	R:R:F12	S:S:P117	7.22	Yes	No	0	1	4
20	R:R:D14	R:R:P15	4.83	No	No	0	6	5
21	R:R:D14	R:R:T16	5.78	No	No	0	6	5
22	R:R:D14	R:R:Y17	3.45	No	Yes	0	6	7
23	R:R:P19	R:R:Y17	4.17	Yes	Yes	9	7	7
24	R:R:S22	R:R:Y17	3.82	No	Yes	0	9	7
25	R:R:Y17	S:S:F116	10.32	Yes	Yes	9	7	7
26	R:R:N18	R:R:P19	3.26	No	Yes	0	7	7
27	R:R:N18	R:R:Q21	3.96	No	No	0	7	4
28	R:R:P19	S:S:F116	8.67	Yes	Yes	9	7	7
29	R:R:P19	S:S:F119	7.22	Yes	Yes	0	7	3
30	R:R:D39	R:R:G20	3.35	No	No	0	1	3
31	R:R:G20	S:S:T110	1.82	No	No	0	3	7
32	R:R:F38	R:R:S22	2.64	Yes	No	0	7	9
33	R:R:I24	R:R:I36	5.89	No	No	0	6	6
34	R:R:F38	R:R:I24	13.82	Yes	No	0	7	6
35	R:R:N25	S:S:N25	6.81	No	No	0	7	7
36	R:R:S28	R:R:Y26	2.54	No	Yes	13	4	6
37	R:R:S34	R:R:Y26	10.17	No	Yes	13	6	6
38	R:R:I36	R:R:Y26	3.63	No	Yes	0	6	6
39	R:R:L113	R:R:Y26	3.52	No	Yes	0	7	6
40	R:R:N32	R:R:T27	4.39	No	No	0	5	5
41	R:R:S28	R:R:S34	6.52	No	No	13	4	6
42	R:R:I29	R:R:Y30	9.67	Yes	Yes	0	4	7
43	R:R:F116	R:R:I29	7.54	Yes	Yes	0	7	4
44	R:R:I29	S:S:F12	3.77	Yes	Yes	0	4	1
45	R:R:Y30	S:S:A5	4	Yes	No	6	7	2
46	R:R:Y30	S:S:P6	4.17	Yes	No	6	7	5
47	R:R:Y30	S:S:L8	2.34	Yes	No	6	7	6
48	R:R:G31	S:S:S9	3.71	No	No	0	8	7
49	R:R:E40	R:R:I36	8.2	No	No	0	3	6
50	R:R:E40	R:R:T37	7.06	No	No	0	3	6
51	R:R:F38	R:R:L41	2.44	Yes	No	0	7	5
52	R:R:F38	S:S:T110	9.08	Yes	No	0	7	7
53	R:R:F38	S:S:L113	2.44	Yes	No	0	7	7
54	R:R:F38	S:S:T114	2.59	Yes	No	0	7	7
55	R:R:L41	R:R:V109	2.98	No	Yes	0	5	5
56	R:R:L41	S:S:V109	2.98	No	Yes	0	5	5
57	R:R:N46	R:R:Q42	10.56	No	No	0	5	7
58	R:R:Q42	S:S:S108	4.33	No	No	0	7	7
59	R:R:Q42	S:S:V109	2.87	No	Yes	0	7	5
60	R:R:V45	S:S:V45	6.41	No	No	0	4	4
61	R:R:N46	S:S:L103	4.12	No	No	0	5	7
62	R:R:T48	S:S:V49	3.17	No	No	0	4	6
63	R:R:V49	S:S:T48	3.17	No	No	0	6	4
64	R:R:V49	S:S:L103	2.98	No	No	0	6	7
65	R:R:Q51	R:R:Y98	3.38	No	Yes	1	4	6
66	R:R:L102	R:R:Q51	3.99	No	No	1	7	4
67	R:R:I53	S:S:F99	10.05	No	Yes	0	7	5
68	R:R:M54	R:R:V276	4.56	No	No	0	7	5
69	R:R:M54	R:R:T279	3.01	No	No	0	7	7
70	R:R:F55	R:R:R58	8.55	Yes	Yes	1	6	9
71	R:R:F55	R:R:H94	3.39	Yes	Yes	1	6	8
72	R:R:F55	R:R:Y98	25.79	Yes	Yes	1	6	6
73	R:R:F55	R:R:F99	2.14	Yes	Yes	1	6	5
74	R:R:F99	R:R:G56	3.01	Yes	No	0	5	7
75	R:R:G56	S:S:V57	1.84	No	No	0	7	6
76	R:R:V57	S:S:G56	1.84	No	No	0	6	7
77	R:R:I91	R:R:R58	3.76	Yes	Yes	0	7	9
78	R:R:H94	R:R:R58	3.39	Yes	Yes	1	8	9
79	R:R:R58	R:R:S95	2.64	Yes	No	1	9	8
80	R:R:R58	R:R:T279	6.47	Yes	No	0	9	7
81	R:R:R58	R:R:T282	2.59	Yes	No	0	9	5
82	R:R:L283	R:R:R58	7.29	No	Yes	0	8	9
83	R:R:C59	R:R:G60	1.96	No	No	0	7	9
84	R:R:C59	R:R:S95	3.44	No	No	1	7	8
85	R:R:C59	R:R:F99	4.19	No	Yes	1	7	5
86	R:R:A62	R:R:L88	3.15	No	Yes	0	8	9
87	R:R:A62	R:R:I91	3.25	No	Yes	0	8	7
88	R:R:A62	R:R:I92	3.25	No	No	0	8	5
89	R:R:A63	R:R:I92	3.25	No	No	0	4	5
90	R:R:L64	S:S:T65	5.9	Yes	No	11	5	7
91	R:R:L64	S:S:L287	2.77	Yes	Yes	11	5	8
92	R:R:L88	R:R:T65	2.95	Yes	No	0	9	7
93	R:R:L287	R:R:T65	4.42	Yes	No	12	8	7
94	R:R:T65	S:S:L64	5.9	No	Yes	12	7	5
95	R:R:L66	R:R:W70	2.28	No	Yes	7	5	4
96	R:R:L66	R:R:Q85	6.65	No	Yes	7	5	5
97	R:R:L66	R:R:L88	2.77	No	Yes	0	5	9
98	R:R:I67	R:R:M71	2.92	No	No	0	5	7
99	R:R:V68	S:S:V68	6.41	No	No	0	7	7
100	R:R:F81	R:R:M69	3.73	Yes	No	7	9	8
101	R:R:M69	R:R:Q85	12.23	No	Yes	7	8	5
102	R:R:M69	R:R:P290	3.35	No	No	0	8	9
103	R:R:R76	R:R:W70	2	No	Yes	7	6	4
104	R:R:F81	R:R:W70	4.01	Yes	Yes	7	9	4
105	R:R:Q85	R:R:W70	13.14	Yes	Yes	7	5	4
106	R:R:F81	R:R:S73	5.28	Yes	No	0	9	8
107	R:R:F81	R:R:R76	8.55	Yes	No	7	9	6
108	R:R:I80	R:R:N84	4.25	No	Yes	14	7	9
109	R:R:I80	R:R:S293	3.1	No	Yes	14	7	9
110	R:R:F81	R:R:Q85	9.37	Yes	Yes	7	9	5
111	R:R:I83	R:R:T144	4.56	No	No	15	7	3
112	R:R:I83	R:R:S145	3.1	No	No	0	7	9
113	R:R:F148	R:R:I83	3.77	Yes	No	15	7	7
114	R:R:N84	R:R:S145	4.47	Yes	No	0	9	9
115	R:R:N84	R:R:P290	3.26	Yes	No	0	9	9
116	R:R:N84	R:R:S293	2.98	Yes	Yes	14	9	9
117	R:R:S141	R:R:S87	4.89	No	No	0	6	8
118	R:R:L88	R:R:V286	2.98	Yes	No	0	9	8
119	R:R:L90	R:R:S141	3	No	No	0	4	6
120	R:R:I91	R:R:L138	5.71	Yes	No	0	7	8
121	R:R:I91	R:R:V286	4.61	Yes	No	0	7	8
122	R:R:L93	R:R:L97	2.77	No	No	0	6	7
123	R:R:I134	R:R:L93	5.71	No	No	0	5	6
124	R:R:H94	R:R:T131	4.11	Yes	No	0	8	6
125	R:R:H94	R:R:I134	5.3	Yes	No	0	8	5
126	R:R:H94	R:R:Q135	6.18	Yes	No	0	8	6
127	R:R:F99	R:R:S95	2.64	Yes	No	1	5	8
128	R:R:Y101	R:R:Y98	6.95	Yes	Yes	0	6	6
129	R:R:L102	R:R:Y98	7.03	No	Yes	1	7	6
130	R:R:F99	S:S:I53	11.3	Yes	No	0	5	7
131	R:R:K100	R:R:V127	4.55	No	No	0	4	5
132	R:R:S107	R:R:Y101	2.54	No	Yes	0	5	6
133	R:R:Y101	R:R:Y128	7.94	Yes	Yes	0	6	8
134	R:R:L103	S:S:N46	4.12	No	No	0	7	5
135	R:R:L103	S:S:V49	2.98	No	No	0	7	6
136	R:R:D124	R:R:S104	4.42	No	No	0	6	6
137	R:R:F119	R:R:N105	14.5	Yes	No	0	3	3
138	R:R:Y106	R:R:Y111	5.96	No	No	16	5	5
139	R:R:I120	R:R:Y106	3.63	No	No	16	7	5
140	R:R:Y106	R:R:Y128	3.97	No	Yes	0	5	8
141	R:R:F119	R:R:S108	2.64	Yes	No	0	3	7
142	R:R:S108	S:S:Q42	4.33	No	No	0	7	7
143	R:R:V109	S:S:L41	2.98	Yes	No	0	5	5
144	R:R:V109	S:S:Q42	2.87	Yes	No	0	5	7
145	R:R:F119	R:R:T110	6.49	Yes	No	0	3	7
146	R:R:T110	S:S:G20	1.82	No	No	0	7	3
147	R:R:T110	S:S:F38	9.08	No	Yes	0	7	7
148	R:R:I120	R:R:Y111	7.25	No	No	16	7	5
149	R:R:V196	R:R:Y111	2.52	No	No	0	1	5
150	R:R:L113	S:S:F38	2.44	No	Yes	0	7	7
151	R:R:F116	R:R:T114	3.89	Yes	No	0	7	7
152	R:R:T114	S:S:F38	2.59	No	Yes	0	7	7
153	R:R:F116	R:R:Q118	5.86	Yes	No	0	7	7
154	R:R:F116	S:S:L11	3.65	Yes	No	10	7	3
155	R:R:F116	S:S:Y17	13.41	Yes	Yes	10	7	7
156	R:R:F116	S:S:P19	8.67	Yes	Yes	10	7	7
157	R:R:P117	R:R:V196	1.77	No	No	0	4	1
158	R:R:P117	S:S:F12	7.22	No	Yes	0	4	1
159	R:R:F119	S:S:P19	7.22	Yes	Yes	0	3	7
160	R:R:D124	R:R:S121	5.89	No	No	0	6	4
161	R:R:R122	R:R:V125	3.92	No	Yes	0	1	4
162	R:R:G123	R:R:H126	4.77	No	No	0	5	6
163	R:R:H126	R:R:V125	4.15	No	Yes	17	6	4
164	R:R:V125	R:R:Y193	3.79	Yes	No	17	4	5
165	R:R:H126	R:R:Y193	10.89	No	No	17	6	5
166	R:R:T192	R:R:Y128	3.75	No	Yes	0	6	8
167	R:R:Q200	R:R:Y128	3.38	No	Yes	0	2	8
168	R:R:G129	R:R:M189	3.49	No	No	0	6	5
169	R:R:Q135	R:R:Y181	2.25	No	Yes	0	6	7
170	R:R:V136	R:R:Y181	2.52	Yes	Yes	0	5	7
171	R:R:I142	R:R:L138	4.28	No	No	0	8	8
172	R:R:V139	R:R:Y181	11.36	No	Yes	0	6	7
173	R:R:A140	R:R:V178	3.39	No	No	0	4	6
174	R:R:I142	R:R:V286	3.07	No	No	0	8	8
175	R:R:E143	R:R:G174	6.55	No	No	18	8	8
176	R:R:E143	R:R:T177	7.06	No	Yes	18	8	8
177	R:R:E143	R:R:S214	8.62	No	No	0	8	9
178	R:R:F148	R:R:T144	2.59	Yes	No	15	7	3
179	R:R:L289	R:R:S145	6.01	No	No	0	9	9
180	R:R:L146	R:R:M218	4.24	No	Yes	0	9	8
181	R:R:F148	R:R:K151	6.2	Yes	No	0	7	6
182	R:R:M218	R:R:Q149	8.16	Yes	Yes	0	8	9
183	R:R:L289	R:R:Q149	3.99	No	Yes	0	9	9
184	R:R:Q149	R:R:S292	4.33	Yes	No	0	9	9
185	R:R:Q149	R:R:S293	4.33	Yes	Yes	0	9	9
186	R:R:I150	R:R:T167	3.04	Yes	No	0	8	7
187	R:R:I150	R:R:S170	3.1	Yes	No	0	8	8
188	R:R:I150	R:R:M218	4.37	Yes	Yes	0	8	8
189	R:R:I150	R:R:V221	4.61	Yes	No	0	8	7
190	R:R:T297	R:R:V152	4.76	No	No	0	6	8
191	R:R:F154	R:R:I153	8.79	Yes	No	0	9	8
192	R:R:I153	R:R:K225	2.91	No	No	0	8	9
193	R:R:A296	R:R:I153	3.25	No	No	0	9	8
194	R:R:F154	R:R:F159	2.14	Yes	Yes	0	9	1
195	R:R:F154	R:R:G163	6.02	Yes	No	0	9	7
196	R:R:F154	R:R:L166	3.65	Yes	No	0	9	7
197	R:R:D157	R:R:K160	4.15	No	No	0	6	5
198	R:R:F159	R:R:N158	3.62	Yes	No	0	1	4
199	R:R:F159	R:R:I162	5.02	Yes	No	0	1	4
200	R:R:F159	R:R:L228	6.09	Yes	No	0	1	3
201	R:R:I162	R:R:L166	2.85	No	No	0	4	7
202	R:R:I169	R:R:M165	2.92	No	No	0	4	2
203	R:R:F217	R:R:L166	4.87	Yes	No	0	6	7
204	R:R:F217	R:R:I169	2.51	Yes	No	0	6	4
205	R:R:F217	R:R:S170	5.28	Yes	No	0	6	8
206	R:R:F171	R:R:I175	7.54	No	No	0	3	4
207	R:R:L173	R:R:S214	3	No	No	0	7	9
208	R:R:G174	R:R:T177	1.82	No	Yes	18	8	8
209	R:R:T177	R:R:Y181	2.5	Yes	Yes	0	8	7
210	R:R:L210	R:R:T177	7.37	No	Yes	0	6	8
211	R:R:M180	R:R:Y203	3.59	No	Yes	0	6	5
212	R:R:S207	R:R:Y181	12.72	No	Yes	0	6	7
213	R:R:F182	R:R:V186	7.87	No	No	0	5	8
214	R:R:S184	R:R:Y203	3.82	No	Yes	0	5	5
215	R:R:I190	R:R:V186	3.07	No	No	0	4	8
216	R:R:K187	R:R:Y203	3.58	No	Yes	0	3	5
217	R:R:M189	R:R:Y193	7.18	No	No	0	5	5
218	R:R:D201	R:R:V191	2.92	No	No	0	2	3
219	R:R:D195	R:R:S197	5.89	No	No	0	3	3
220	R:R:D201	R:R:Y203	2.3	No	Yes	0	2	5
221	R:R:I209	R:R:N205	2.83	No	No	0	8	6
222	R:R:F262	R:R:T208	2.59	Yes	No	0	7	6
223	R:R:I209	R:R:Y266	7.25	No	Yes	0	8	6
224	R:R:I215	R:R:L211	2.85	Yes	No	19	8	6
225	R:R:F262	R:R:L211	2.44	Yes	No	19	7	6
226	R:R:A212	R:R:F262	4.16	No	Yes	0	7	7
227	R:R:A212	R:R:Y266	2.67	No	Yes	0	7	6
228	R:R:I215	R:R:S214	3.1	Yes	No	0	8	9
229	R:R:I215	R:R:S259	3.1	Yes	No	0	8	8
230	R:R:F262	R:R:I215	3.77	Yes	Yes	19	7	8
231	R:R:N216	R:R:S259	8.94	No	No	0	7	8
232	R:R:I263	R:R:N216	4.25	No	No	0	7	7
233	R:R:F217	R:R:V221	6.55	Yes	No	0	6	7
234	R:R:L222	R:R:M218	5.65	Yes	Yes	0	9	8
235	R:R:L255	R:R:M218	2.83	No	Yes	0	9	8
236	R:R:S219	R:R:S259	6.52	No	No	0	9	8
237	R:R:F220	R:R:V224	7.87	No	No	0	4	4
238	R:R:L222	R:R:S254	3	Yes	No	0	9	9
239	R:R:L222	R:R:S292	3	Yes	No	0	9	9
240	R:R:L222	R:R:W295	4.56	Yes	Yes	0	9	9
241	R:R:K225	R:R:W295	10.44	No	Yes	0	9	9
242	R:R:K225	R:R:N300	2.8	No	Yes	0	9	7
243	R:R:I249	R:R:L226	2.85	No	No	0	9	9
244	R:R:L226	R:R:W295	3.42	No	Yes	0	9	9
245	R:R:A229	R:R:N300	4.69	No	Yes	0	9	7
246	R:R:I230	R:R:Q240	5.49	No	No	0	9	8
247	R:R:F241	R:R:I230	2.51	Yes	No	3	9	9
248	R:R:H245	R:R:I230	6.63	No	No	3	9	9
249	R:R:N300	R:R:S232	2.98	Yes	No	20	7	7
250	R:R:N301	R:R:S232	5.96	Yes	No	20	6	7
251	R:R:F241	R:R:R233	10.69	Yes	No	0	9	9
252	R:R:N301	R:R:R233	2.41	Yes	No	0	6	9
253	R:R:Q240	R:R:R234	3.5	No	No	0	8	8
254	R:R:F241	R:R:F244	8.57	Yes	No	3	9	9
255	R:R:F241	R:R:H245	6.79	Yes	No	3	9	9
256	R:R:D242	R:R:S243	4.42	No	No	0	8	7
257	R:R:F244	R:R:L247	3.65	No	Yes	3	9	9
258	R:R:F244	R:R:L248	7.31	No	No	3	9	8
259	R:R:I246	R:R:M250	2.92	No	No	0	8	9
260	R:R:L247	R:R:L248	4.15	Yes	No	3	9	8
261	R:R:L247	R:R:S251	7.51	Yes	No	3	9	8
262	R:R:L247	R:R:Q253	2.66	Yes	No	3	9	9
263	R:R:L248	R:R:W295	9.11	No	Yes	0	8	9
264	R:R:Q253	R:R:S251	5.78	No	No	3	9	8
265	R:R:C252	R:R:P258	1.88	No	Yes	21	7	9
266	R:R:C252	R:R:S288	6.89	No	No	21	7	8
267	R:R:Q253	R:R:W295	2.19	No	Yes	0	9	9
268	R:R:L255	R:R:P258	3.28	No	Yes	0	9	9
269	R:R:L255	R:R:S292	9.01	No	No	0	9	9
270	R:R:P258	R:R:V257	3.53	Yes	No	0	9	7
271	R:R:L284	R:R:P258	3.28	No	Yes	0	6	9
272	R:R:A285	R:R:P258	1.87	No	Yes	0	9	9
273	R:R:P258	R:R:S288	5.34	Yes	No	21	9	8
274	R:R:I261	R:R:L277	2.85	No	No	0	7	7
275	R:R:A281	R:R:I261	3.25	No	No	0	7	7
276	R:R:A281	R:R:F262	8.32	No	Yes	0	7	7
277	R:R:F262	R:R:T282	2.59	Yes	No	0	7	5
278	R:R:I263	R:R:Y266	4.84	No	Yes	0	7	6
279	R:R:L268	R:R:Q272	5.32	No	No	0	4	1
280	R:R:K269	R:R:Q272	6.78	No	No	0	2	1
281	R:R:N271	R:R:Q272	5.28	No	No	0	4	1
282	R:R:L283	R:R:L287	4.15	No	Yes	0	8	8
283	R:R:L287	S:S:L64	2.77	Yes	Yes	12	8	5
284	R:R:A299	R:R:A302	1.79	No	No	0	6	5
285	R:R:N300	R:R:N301	6.81	Yes	Yes	20	7	6
286	S:S:A5	S:S:P6	1.87	No	No	6	2	5
287	S:S:F12	S:S:L8	7.31	Yes	No	6	1	6
288	S:S:L8	S:S:Y13	2.34	No	No	6	6	2
289	S:S:L11	S:S:S9	4.5	No	No	0	3	7
290	S:S:L11	S:S:Y17	11.72	No	Yes	10	3	7
291	S:S:F12	S:S:Y13	7.22	Yes	No	6	1	2
292	S:S:D14	S:S:P15	4.83	No	No	0	6	5
293	S:S:D14	S:S:T16	5.78	No	No	0	6	5
294	S:S:D14	S:S:Y17	3.45	No	Yes	0	6	7
295	S:S:P19	S:S:Y17	4.17	Yes	Yes	10	7	7
296	S:S:S22	S:S:Y17	3.82	No	Yes	0	9	7
297	S:S:N18	S:S:P19	3.26	No	Yes	0	7	7
298	S:S:N18	S:S:Q21	3.96	No	No	0	7	4
299	S:S:D39	S:S:G20	3.35	No	No	0	1	3
300	S:S:F38	S:S:S22	2.64	Yes	No	0	7	9
301	S:S:I24	S:S:I36	5.89	No	No	0	6	6
302	S:S:F38	S:S:I24	13.82	Yes	No	0	7	6
303	S:S:S28	S:S:Y26	2.54	No	Yes	22	4	6
304	S:S:S34	S:S:Y26	10.17	No	Yes	22	6	6
305	S:S:I36	S:S:Y26	3.63	No	Yes	0	6	6
306	S:S:L113	S:S:Y26	3.52	No	Yes	0	7	6
307	S:S:N32	S:S:T27	4.39	No	No	0	5	5
308	S:S:S28	S:S:S34	6.52	No	No	22	4	6
309	S:S:I29	S:S:Y30	9.67	Yes	Yes	0	4	7
310	S:S:F116	S:S:I29	7.54	Yes	Yes	0	7	4
311	S:S:E40	S:S:I36	8.2	No	No	0	3	6
312	S:S:E40	S:S:T37	7.06	No	No	0	3	6
313	S:S:F38	S:S:L41	2.44	Yes	No	0	7	5
314	S:S:L41	S:S:V109	2.98	No	Yes	0	5	5
315	S:S:N46	S:S:Q42	10.56	No	No	0	5	7
316	S:S:Q51	S:S:Y98	3.38	No	Yes	2	4	6
317	S:S:L102	S:S:Q51	3.99	No	No	2	7	4
318	S:S:M54	S:S:V276	4.56	No	No	0	7	5
319	S:S:M54	S:S:T279	3.01	No	No	0	7	7
320	S:S:F55	S:S:R58	8.55	Yes	Yes	2	6	9
321	S:S:F55	S:S:H94	3.39	Yes	Yes	2	6	8
322	S:S:F55	S:S:Y98	25.79	Yes	Yes	2	6	6
323	S:S:F55	S:S:F99	2.14	Yes	Yes	2	6	5
324	S:S:F99	S:S:G56	3.01	Yes	No	0	5	7
325	S:S:I91	S:S:R58	3.76	Yes	Yes	0	7	9
326	S:S:H94	S:S:R58	3.39	Yes	Yes	2	8	9
327	S:S:R58	S:S:S95	2.64	Yes	No	2	9	8
328	S:S:R58	S:S:T279	6.47	Yes	No	0	9	7
329	S:S:R58	S:S:T282	2.59	Yes	No	0	9	5
330	S:S:L283	S:S:R58	7.29	No	Yes	0	8	9
331	S:S:C59	S:S:G60	1.96	No	No	0	7	9
332	S:S:C59	S:S:S95	3.44	No	No	2	7	8
333	S:S:C59	S:S:F99	4.19	No	Yes	2	7	5
334	S:S:A62	S:S:L88	3.15	No	Yes	0	8	9
335	S:S:A62	S:S:I91	3.25	No	Yes	0	8	7
336	S:S:A62	S:S:I92	3.25	No	No	0	8	5
337	S:S:A63	S:S:I92	3.25	No	No	0	4	5
338	S:S:L88	S:S:T65	2.95	Yes	No	0	9	7
339	S:S:L287	S:S:T65	4.42	Yes	No	11	8	7
340	S:S:L66	S:S:W70	2.28	No	Yes	8	5	4
341	S:S:L66	S:S:Q85	6.65	No	Yes	8	5	5
342	S:S:L66	S:S:L88	2.77	No	Yes	0	5	9
343	S:S:I67	S:S:M71	2.92	No	No	0	5	7
344	S:S:F81	S:S:M69	3.73	Yes	No	8	9	8
345	S:S:M69	S:S:Q85	12.23	No	Yes	8	8	5
346	S:S:M69	S:S:P290	3.35	No	No	0	8	9
347	S:S:R76	S:S:W70	2	No	Yes	8	6	4
348	S:S:F81	S:S:W70	4.01	Yes	Yes	8	9	4
349	S:S:Q85	S:S:W70	13.14	Yes	Yes	8	5	4
350	S:S:F81	S:S:S73	5.28	Yes	No	0	9	8
351	S:S:F81	S:S:R76	8.55	Yes	No	8	9	6
352	S:S:I80	S:S:N84	4.25	No	Yes	23	7	9
353	S:S:I80	S:S:S293	3.1	No	Yes	23	7	9
354	S:S:F81	S:S:Q85	9.37	Yes	Yes	8	9	5
355	S:S:I83	S:S:T144	4.56	No	No	24	7	3
356	S:S:I83	S:S:S145	3.1	No	No	0	7	9
357	S:S:F148	S:S:I83	3.77	Yes	No	24	7	7
358	S:S:N84	S:S:S145	4.47	Yes	No	0	9	9
359	S:S:N84	S:S:P290	3.26	Yes	No	0	9	9
360	S:S:N84	S:S:S293	2.98	Yes	Yes	23	9	9
361	S:S:S141	S:S:S87	4.89	No	No	0	6	8
362	S:S:L88	S:S:V286	2.98	Yes	No	0	9	8
363	S:S:L90	S:S:S141	3	No	No	0	4	6
364	S:S:I91	S:S:L138	5.71	Yes	No	0	7	8
365	S:S:I91	S:S:V286	4.61	Yes	No	0	7	8
366	S:S:L93	S:S:L97	2.77	No	No	0	6	7
367	S:S:I134	S:S:L93	5.71	No	No	0	5	6
368	S:S:H94	S:S:T131	4.11	Yes	No	0	8	6
369	S:S:H94	S:S:I134	5.3	Yes	No	0	8	5
370	S:S:H94	S:S:Q135	6.18	Yes	No	0	8	6
371	S:S:F99	S:S:S95	2.64	Yes	No	2	5	8
372	S:S:Y101	S:S:Y98	6.95	Yes	Yes	0	6	6
373	S:S:L102	S:S:Y98	7.03	No	Yes	2	7	6
374	S:S:K100	S:S:V127	4.55	No	No	0	4	5
375	S:S:S107	S:S:Y101	2.54	No	Yes	0	5	6
376	S:S:Y101	S:S:Y128	7.94	Yes	Yes	0	6	8
377	S:S:D124	S:S:S104	4.42	No	No	0	6	6
378	S:S:F119	S:S:N105	14.5	Yes	No	0	3	3
379	S:S:Y106	S:S:Y111	4.96	No	No	25	5	5
380	S:S:I120	S:S:Y106	3.63	No	No	25	7	5
381	S:S:Y106	S:S:Y128	3.97	No	Yes	0	5	8
382	S:S:F119	S:S:S108	2.64	Yes	No	0	3	7
383	S:S:F119	S:S:T110	6.49	Yes	No	0	3	7
384	S:S:I120	S:S:Y111	7.25	No	No	25	7	5
385	S:S:V196	S:S:Y111	2.52	No	No	0	1	5
386	S:S:F116	S:S:T114	3.89	Yes	No	0	7	7
387	S:S:F116	S:S:Q118	5.86	Yes	No	0	7	7
388	S:S:P117	S:S:V196	1.77	No	No	0	4	1
389	S:S:D124	S:S:S121	5.89	No	No	0	6	4
390	S:S:R122	S:S:V125	3.92	No	Yes	0	1	4
391	S:S:G123	S:S:H126	4.77	No	No	0	5	6
392	S:S:H126	S:S:V125	4.15	No	Yes	26	6	4
393	S:S:V125	S:S:Y193	3.79	Yes	No	26	4	5
394	S:S:H126	S:S:Y193	10.89	No	No	26	6	5
395	S:S:T192	S:S:Y128	3.75	No	Yes	0	6	8
396	S:S:Q200	S:S:Y128	6.76	No	Yes	0	2	8
397	S:S:G129	S:S:M189	3.49	No	No	0	6	5
398	S:S:Q135	S:S:Y181	2.25	No	Yes	0	6	7
399	S:S:V136	S:S:Y181	2.52	Yes	Yes	0	5	7
400	S:S:I142	S:S:L138	4.28	No	No	0	8	8
401	S:S:V139	S:S:Y181	11.36	No	Yes	0	6	7
402	S:S:A140	S:S:V178	3.39	No	No	0	4	6
403	S:S:I142	S:S:V286	3.07	No	No	0	8	8
404	S:S:E143	S:S:G174	6.55	No	No	27	8	8
405	S:S:E143	S:S:T177	7.06	No	Yes	27	8	8
406	S:S:E143	S:S:S214	8.62	No	No	0	8	9
407	S:S:F148	S:S:T144	2.59	Yes	No	24	7	3
408	S:S:L289	S:S:S145	6.01	No	No	0	9	9
409	S:S:L146	S:S:M218	4.24	No	Yes	0	9	8
410	S:S:F148	S:S:K151	6.2	Yes	No	0	7	6
411	S:S:M218	S:S:Q149	8.16	Yes	Yes	0	8	9
412	S:S:L289	S:S:Q149	3.99	No	Yes	0	9	9
413	S:S:Q149	S:S:S292	4.33	Yes	No	0	9	9
414	S:S:Q149	S:S:S293	4.33	Yes	Yes	0	9	9
415	S:S:I150	S:S:T167	3.04	Yes	No	0	8	7
416	S:S:I150	S:S:S170	3.1	Yes	No	0	8	8
417	S:S:I150	S:S:M218	4.37	Yes	Yes	0	8	8
418	S:S:I150	S:S:V221	4.61	Yes	No	0	8	7
419	S:S:T297	S:S:V152	4.76	No	No	0	6	8
420	S:S:F154	S:S:I153	8.79	Yes	No	0	9	8
421	S:S:I153	S:S:K225	2.91	No	No	0	8	9
422	S:S:A296	S:S:I153	3.25	No	No	0	9	8
423	S:S:F154	S:S:F159	2.14	Yes	Yes	0	9	1
424	S:S:F154	S:S:G163	6.02	Yes	No	0	9	7
425	S:S:F154	S:S:L166	3.65	Yes	No	0	9	7
426	S:S:D157	S:S:K160	4.15	No	No	0	6	5
427	S:S:F159	S:S:N158	3.62	Yes	No	0	1	4
428	S:S:F159	S:S:I162	5.02	Yes	No	0	1	4
429	S:S:F159	S:S:L228	6.09	Yes	No	0	1	3
430	S:S:I162	S:S:L166	2.85	No	No	0	4	7
431	S:S:I169	S:S:M165	2.92	No	No	0	4	2
432	S:S:F217	S:S:L166	4.87	Yes	No	0	6	7
433	S:S:F217	S:S:I169	2.51	Yes	No	0	6	4
434	S:S:F217	S:S:S170	5.28	Yes	No	0	6	8
435	S:S:F171	S:S:I175	7.54	No	No	0	3	4
436	S:S:L173	S:S:S214	3	No	No	0	7	9
437	S:S:G174	S:S:T177	1.82	No	Yes	27	8	8
438	S:S:T177	S:S:Y181	2.5	Yes	Yes	0	8	7
439	S:S:L210	S:S:T177	7.37	No	Yes	0	6	8
440	S:S:M180	S:S:Y203	3.59	No	Yes	0	6	5
441	S:S:S207	S:S:Y181	12.72	No	Yes	0	6	7
442	S:S:F182	S:S:V186	7.87	No	No	0	5	8
443	S:S:S184	S:S:Y203	3.82	No	Yes	0	5	5
444	S:S:I190	S:S:V186	3.07	No	No	0	4	8
445	S:S:K187	S:S:Y203	3.58	No	Yes	0	3	5
446	S:S:M189	S:S:Y193	7.18	No	No	0	5	5
447	S:S:D201	S:S:V191	2.92	No	No	0	2	3
448	S:S:D195	S:S:S197	5.89	No	No	0	3	3
449	S:S:D201	S:S:Y203	2.3	No	Yes	0	2	5
450	S:S:I209	S:S:N205	2.83	No	No	0	8	6
451	S:S:F262	S:S:T208	2.59	Yes	No	0	7	6
452	S:S:I209	S:S:Y266	7.25	No	Yes	0	8	6
453	S:S:I215	S:S:L211	2.85	Yes	No	28	8	6
454	S:S:F262	S:S:L211	2.44	Yes	No	28	7	6
455	S:S:A212	S:S:F262	4.16	No	Yes	0	7	7
456	S:S:A212	S:S:Y266	2.67	No	Yes	0	7	6
457	S:S:I215	S:S:S214	3.1	Yes	No	0	8	9
458	S:S:I215	S:S:S259	3.1	Yes	No	0	8	8
459	S:S:F262	S:S:I215	3.77	Yes	Yes	28	7	8
460	S:S:N216	S:S:S259	8.94	No	No	0	7	8
461	S:S:I263	S:S:N216	4.25	No	No	0	7	7
462	S:S:F217	S:S:V221	6.55	Yes	No	0	6	7
463	S:S:L222	S:S:M218	5.65	Yes	Yes	0	9	8
464	S:S:L255	S:S:M218	2.83	No	Yes	0	9	8
465	S:S:S219	S:S:S259	6.52	No	No	0	9	8
466	S:S:F220	S:S:V224	7.87	No	No	0	4	4
467	S:S:L222	S:S:S254	3	Yes	No	0	9	9
468	S:S:L222	S:S:S292	3	Yes	No	0	9	9
469	S:S:L222	S:S:W295	4.56	Yes	Yes	0	9	9
470	S:S:K225	S:S:W295	10.44	No	Yes	0	9	9
471	S:S:K225	S:S:N300	2.8	No	Yes	0	9	7
472	S:S:I249	S:S:L226	2.85	No	No	0	9	9
473	S:S:L226	S:S:W295	3.42	No	Yes	0	9	9
474	S:S:A229	S:S:N300	4.69	No	Yes	0	9	7
475	S:S:I230	S:S:Q240	5.49	No	No	0	9	8
476	S:S:F241	S:S:I230	2.51	Yes	No	4	9	9
477	S:S:H245	S:S:I230	6.63	No	No	4	9	9
478	S:S:N300	S:S:S232	2.98	Yes	No	29	7	7
479	S:S:N301	S:S:S232	5.96	Yes	No	29	6	7
480	S:S:F241	S:S:R233	9.62	Yes	No	0	9	9
481	S:S:N301	S:S:R233	2.41	Yes	No	0	6	9
482	S:S:Q240	S:S:R234	3.5	No	No	0	8	8
483	S:S:F241	S:S:F244	10.72	Yes	No	4	9	9
484	S:S:F241	S:S:H245	6.79	Yes	No	4	9	9
485	S:S:F244	S:S:L247	3.65	No	Yes	4	9	9
486	S:S:F244	S:S:L248	7.31	No	No	4	9	8
487	S:S:I246	S:S:M250	4.37	No	No	0	8	9
488	S:S:L247	S:S:L248	4.15	Yes	No	4	9	8
489	S:S:L247	S:S:S251	7.51	Yes	No	4	9	8
490	S:S:L247	S:S:Q253	2.66	Yes	No	4	9	9
491	S:S:L248	S:S:W295	9.11	No	Yes	0	8	9
492	S:S:Q253	S:S:S251	5.78	No	No	4	9	8
493	S:S:C252	S:S:P258	1.88	No	Yes	30	7	9
494	S:S:C252	S:S:S288	6.89	No	No	30	7	8
495	S:S:Q253	S:S:W295	2.19	No	Yes	0	9	9
496	S:S:L255	S:S:P258	3.28	No	Yes	0	9	9
497	S:S:L255	S:S:S292	9.01	No	No	0	9	9
498	S:S:P258	S:S:V257	3.53	Yes	No	0	9	7
499	S:S:L284	S:S:P258	3.28	No	Yes	0	6	9
500	S:S:A285	S:S:P258	1.87	No	Yes	0	9	9
501	S:S:P258	S:S:S288	5.34	Yes	No	30	9	8
502	S:S:I261	S:S:L277	2.85	No	No	0	7	7
503	S:S:A281	S:S:I261	3.25	No	No	0	7	7
504	S:S:A281	S:S:F262	8.32	No	Yes	0	7	7
505	S:S:F262	S:S:T282	2.59	Yes	No	0	7	5
506	S:S:I263	S:S:Y266	4.84	No	Yes	0	7	6
507	S:S:L268	S:S:Q272	5.32	No	No	0	4	1
508	S:S:K269	S:S:Q272	6.78	No	No	0	2	1
509	S:S:N271	S:S:Q272	5.28	No	No	0	4	1
510	S:S:L283	S:S:L287	4.15	No	Yes	0	8	8
511	S:S:A299	S:S:A302	1.79	No	No	0	6	5
512	S:S:N300	S:S:N301	6.81	Yes	Yes	29	7	6
513	R:R:G115	R:R:I29	1.76	No	Yes	0	2	4
514	S:S:G115	S:S:I29	1.76	No	Yes	0	2	4
515	R:R:P79	R:R:T78	1.75	No	No	0	4	8
516	R:R:P270	R:R:T274	1.75	No	No	0	2	6
517	S:S:P79	S:S:T78	1.75	No	No	0	4	8
518	S:S:P270	S:S:T274	1.75	No	No	0	2	6
519	R:R:G31	R:R:N32	1.7	No	No	0	8	5
520	R:R:A185	R:R:V136	1.7	No	Yes	0	6	5
521	R:R:A198	R:R:V191	1.7	No	No	0	1	3
522	S:S:G31	S:S:N32	1.7	No	No	0	8	5
523	S:S:A185	S:S:V136	1.7	No	Yes	0	6	5
524	S:S:A198	S:S:V191	1.7	No	No	0	1	3
525	R:R:D201	R:R:G188	1.68	No	No	0	2	8
526	R:R:K269	R:R:P270	1.67	No	No	0	2	2
527	S:S:K269	S:S:P270	1.67	No	No	0	2	2
528	R:R:G188	R:R:Q200	1.64	No	No	0	8	2
529	R:R:A52	S:S:I53	1.62	No	No	0	6	7
530	R:R:I53	S:S:A52	1.62	No	No	0	7	6
531	R:R:S141	R:R:V86	1.62	No	No	0	6	4
532	R:R:S170	R:R:V147	1.62	No	No	0	8	7
533	S:S:S141	S:S:V86	1.62	No	No	0	6	4
534	S:S:S170	S:S:V147	1.62	No	No	0	8	7
535	R:R:A206	R:R:M180	1.61	No	No	0	5	6
536	S:S:A206	S:S:M180	1.61	No	No	0	5	6
537	R:R:V45	R:R:V49	1.6	No	No	0	4	6
538	R:R:V109	R:R:V45	1.6	Yes	No	0	5	4
539	R:R:V125	R:R:V196	1.6	Yes	No	0	4	1
540	R:R:V136	R:R:V178	1.6	Yes	No	0	5	6
541	R:R:V139	R:R:V178	1.6	No	No	0	6	6
542	S:S:V45	S:S:V49	1.6	No	No	0	4	6
543	S:S:V109	S:S:V45	1.6	Yes	No	0	5	4
544	S:S:V125	S:S:V196	1.6	Yes	No	0	4	1
545	S:S:V136	S:S:V178	1.6	Yes	No	0	5	6
546	S:S:V139	S:S:V178	1.6	No	No	0	6	6
547	R:R:T72	R:R:V68	1.59	No	No	0	7	7
548	R:R:T155	R:R:V152	1.59	No	No	0	6	8
549	R:R:T179	R:R:V183	1.59	No	No	0	5	6
550	R:R:C252	R:R:L291	1.59	No	No	0	7	8
551	S:S:T72	S:S:V68	1.59	No	No	0	7	7
552	S:S:T155	S:S:V152	1.59	No	No	0	6	8
553	S:S:T179	S:S:V183	1.59	No	No	0	5	6
554	S:S:C252	S:S:L291	1.59	No	No	0	7	8
555	R:R:A112	R:R:L44	1.58	No	No	0	3	4
556	R:R:A61	R:R:L287	1.58	No	Yes	12	8	8
557	R:R:A61	S:S:L64	1.58	No	Yes	12	8	5
558	R:R:L64	S:S:A61	1.58	Yes	No	11	5	8
559	R:R:A265	R:R:L277	1.58	No	No	0	8	7
560	S:S:A112	S:S:L44	1.58	No	No	0	3	4
561	S:S:A61	S:S:L287	1.58	No	Yes	11	8	8
562	S:S:A265	S:S:L277	1.58	No	No	0	8	7
563	R:R:T23	R:R:T37	1.57	No	No	0	5	6
564	R:R:T208	R:R:T278	1.57	No	Yes	0	6	5
565	R:R:T278	R:R:T279	1.57	Yes	No	0	5	7
566	R:R:T278	R:R:T282	1.57	Yes	No	0	5	5
567	S:S:T23	S:S:T37	1.57	No	No	0	5	6
568	S:S:T208	S:S:T278	1.57	No	Yes	0	6	5
569	S:S:T278	S:S:T279	1.57	Yes	No	0	5	7
570	S:S:T278	S:S:T282	1.57	Yes	No	0	5	5
571	R:R:A185	R:R:N132	1.56	No	No	0	6	7
572	S:S:A185	S:S:N132	1.56	No	No	0	6	7
573	R:R:I209	R:R:S213	1.55	No	No	0	8	6
574	R:R:I246	R:R:S243	1.55	No	No	0	8	7
575	S:S:I209	S:S:S213	1.55	No	No	0	8	6
576	S:S:I246	S:S:S243	1.55	No	No	0	8	7
577	R:R:I80	R:R:V152	1.54	No	No	0	7	8
578	R:R:A198	R:R:D195	1.54	No	No	0	1	3
579	R:R:I227	R:R:V223	1.54	No	No	0	5	6
580	S:S:I80	S:S:V152	1.54	No	No	0	7	8
581	S:S:A198	S:S:D195	1.54	No	No	0	1	3
582	S:S:I227	S:S:V223	1.54	No	No	0	5	6
583	R:R:M294	R:R:S293	1.53	No	Yes	0	8	9
584	S:S:M180	S:S:S207	1.53	No	No	0	6	6
585	S:S:M294	S:S:S293	1.53	No	Yes	0	8	9
586	R:R:I175	R:R:T179	1.52	No	No	0	4	5
587	S:S:I175	S:S:T179	1.52	No	No	0	4	5
588	R:R:M71	R:R:T72	1.51	No	No	0	7	7
589	S:S:M71	S:S:T72	1.51	No	No	0	7	7
590	R:R:L164	R:R:S168	1.5	No	No	0	1	3
591	S:S:L164	S:S:S168	1.5	No	No	0	1	3
592	R:R:L64	R:R:V68	1.49	Yes	No	0	5	7
593	R:R:L284	R:R:V280	1.49	No	No	0	6	7
594	S:S:L64	S:S:V68	1.49	Yes	No	0	5	7
595	S:S:L284	S:S:V280	1.49	No	No	0	6	7
596	R:R:T50	S:S:L103	1.47	No	No	0	4	7
597	R:R:L103	S:S:T50	1.47	No	No	0	7	4
598	S:S:D242	S:S:S243	1.47	No	No	0	8	7
599	S:S:I249	S:S:M250	1.46	No	No	0	9	9
600	R:R:D275	R:R:T278	1.45	No	Yes	0	5	5
601	S:S:D275	S:S:T278	1.45	No	Yes	0	5	5
602	R:R:F148	R:R:P79	1.44	Yes	No	0	7	4
603	S:S:F148	S:S:P79	1.44	Yes	No	0	7	4
604	R:R:I249	R:R:L256	1.43	No	No	0	9	6
605	R:R:I260	R:R:L256	1.43	No	No	0	8	6
606	R:R:I260	R:R:L264	1.43	No	No	0	8	7
607	S:S:I249	S:S:L256	1.43	No	No	0	9	6
608	S:S:I260	S:S:L256	1.43	No	No	0	8	6
609	S:S:I260	S:S:L264	1.43	No	No	0	8	7
610	R:R:D124	R:R:I120	1.4	No	No	0	6	7
611	S:S:D124	S:S:I120	1.4	No	No	0	6	7
612	R:R:L113	R:R:L44	1.38	No	No	0	7	4
613	R:R:L137	R:R:L90	1.38	No	No	0	6	4
614	R:R:L138	R:R:L90	1.38	No	No	0	8	4
615	S:S:L113	S:S:L44	1.38	No	No	0	7	4
616	S:S:L137	S:S:L90	1.38	No	No	0	6	4
617	S:S:L138	S:S:L90	1.38	No	No	0	8	4
618	R:R:L236	R:R:N301	1.37	No	Yes	0	9	6
619	S:S:L236	S:S:N301	1.37	No	Yes	0	9	6
620	R:R:D195	R:R:N194	1.35	No	No	0	3	1
621	S:S:D195	S:S:N194	1.35	No	No	0	3	1
622	R:R:F182	R:R:V136	1.31	No	Yes	0	5	5
623	R:R:F220	R:R:V221	1.31	No	No	0	4	7
624	S:S:F182	S:S:V136	1.31	No	Yes	0	5	5
625	S:S:F220	S:S:V221	1.31	No	No	0	4	7
626	R:R:A298	R:R:W295	1.3	No	Yes	0	7	9
627	S:S:A298	S:S:W295	1.3	No	Yes	0	7	9
628	R:R:S267	R:R:Y266	1.27	No	Yes	0	4	6
629	S:S:S267	S:S:Y266	1.27	No	Yes	0	4	6
630	R:R:V127	R:R:Y101	1.26	No	Yes	0	5	6
631	S:S:V127	S:S:Y101	1.26	No	Yes	0	5	6
632	R:R:K239	R:R:R233	1.24	No	No	0	6	9
633	S:S:K239	S:S:R233	1.24	No	No	0	6	9
634	R:R:N10	R:R:Y13	1.16	No	No	0	4	2
635	S:S:N10	S:S:Y13	1.16	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F12	6.38	4	5	1
2	R:R:Y17	6.696	5	9	7
3	R:R:P19	5.83	4	9	7
4	R:R:Y26	4.965	4	13	6
5	R:R:I29	5.685	4	0	4
6	R:R:Y30	5.045	4	6	7
7	R:R:F38	5.50167	6	0	7
8	R:R:F55	9.9675	4	1	6
9	R:R:R58	4.95571	7	1	9
10	R:R:L64	2.935	4	11	5
11	R:R:W70	5.3575	4	7	4
12	R:R:F81	6.188	5	7	9
13	R:R:N84	3.74	4	14	9
14	R:R:Q85	10.3475	4	7	5
15	R:R:L88	2.9625	4	0	9
16	R:R:I91	4.3325	4	0	7
17	R:R:H94	4.474	5	1	8
18	R:R:Y98	10.7875	4	1	6
19	R:R:F99	4.656	5	1	5
20	R:R:Y101	4.6725	4	0	6
21	R:R:V109	2.6075	4	0	5
22	R:R:F116	7.17	6	10	7
23	R:R:F119	7.7125	4	0	3
24	R:R:V125	3.365	4	17	4
25	R:R:Y128	4.76	4	0	8
26	R:R:V136	1.7825	4	0	5
27	R:R:F148	3.5	4	15	7
28	R:R:Q149	5.2025	4	0	9
29	R:R:I150	3.78	4	0	8
30	R:R:F154	5.15	4	0	9
31	R:R:F159	4.2175	4	0	1
32	R:R:T177	4.6875	4	18	8
33	R:R:Y181	6.27	5	0	7
34	R:R:Y203	3.3225	4	0	5
35	R:R:I215	3.205	4	19	8
36	R:R:F217	4.8025	4	0	6
37	R:R:M218	5.05	5	0	8
38	R:R:L222	4.0525	4	0	9
39	R:R:F241	7.14	4	3	9
40	R:R:L247	4.4925	4	3	9
41	R:R:P258	3.19667	6	21	9
42	R:R:F262	3.97833	6	19	7
43	R:R:Y266	4.0075	4	0	6
44	R:R:T278	1.54	4	0	5
45	R:R:L287	3.23	4	12	8
46	R:R:S293	2.985	4	14	9
47	R:R:W295	5.17	6	0	9
48	R:R:N300	4.32	4	20	7
49	R:R:N301	4.1375	4	20	6
50	S:S:F12	6.38	4	6	1
51	S:S:Y17	7.314	5	10	7
52	S:S:P19	5.83	4	10	7
53	S:S:Y26	4.965	4	22	6
54	S:S:I29	5.685	4	0	4
55	S:S:Y30	5.3925	4	5	7
56	S:S:F38	5.50167	6	0	7
57	S:S:F55	9.9675	4	2	6
58	S:S:R58	4.95571	7	2	9
59	S:S:L64	2.935	4	12	5
60	S:S:W70	5.3575	4	8	4
61	S:S:F81	6.188	5	8	9
62	S:S:N84	3.74	4	23	9
63	S:S:Q85	10.3475	4	8	5
64	S:S:L88	2.9625	4	0	9
65	S:S:I91	4.3325	4	0	7
66	S:S:H94	4.474	5	2	8
67	S:S:Y98	10.7875	4	2	6
68	S:S:F99	4.406	5	2	5
69	S:S:Y101	4.6725	4	0	6
70	S:S:V109	2.6075	4	0	5
71	S:S:F116	6.45333	6	9	7
72	S:S:F119	7.7125	4	0	3
73	S:S:V125	3.365	4	26	4
74	S:S:Y128	5.605	4	0	8
75	S:S:V136	1.7825	4	0	5
76	S:S:F148	3.5	4	24	7
77	S:S:Q149	5.2025	4	0	9
78	S:S:I150	3.78	4	0	8
79	S:S:F154	5.15	4	0	9
80	S:S:F159	4.2175	4	0	1
81	S:S:T177	4.6875	4	27	8
82	S:S:Y181	6.27	5	0	7
83	S:S:Y203	3.3225	4	0	5
84	S:S:I215	3.205	4	28	8
85	S:S:F217	4.8025	4	0	6
86	S:S:M218	5.05	5	0	8
87	S:S:L222	4.0525	4	0	9
88	S:S:F241	7.41	4	4	9
89	S:S:L247	4.4925	4	4	9
90	S:S:P258	3.19667	6	30	9
91	S:S:F262	3.97833	6	28	7
92	S:S:Y266	4.0075	4	0	6
93	S:S:T278	1.54	4	0	5
94	S:S:L287	3.23	4	11	8
95	S:S:S293	2.985	4	23	9
96	S:S:W295	5.17	6	0	9
97	S:S:N300	4.32	4	29	7
98	S:S:N301	4.1375	4	29	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F116	R:R:T114	28.9377	3.89	Yes	No	0	7	7
2	R:R:T114	S:S:F38	28.7121	2.59	No	Yes	0	7	7
3	S:S:F38	S:S:L41	25.8919	2.44	Yes	No	0	7	5
4	R:R:V109	S:S:L41	11.9882	2.98	Yes	No	0	5	5
5	R:R:L41	R:R:V109	14.4496	2.98	No	Yes	0	5	5
6	R:R:F38	R:R:L41	26.1303	2.44	Yes	No	0	7	5
7	S:S:L41	S:S:V109	14.3195	2.98	No	Yes	0	5	5
8	R:R:L41	S:S:V109	12.0605	2.98	No	Yes	0	5	5
9	R:R:F38	S:S:T114	29.368	2.59	Yes	No	0	7	7
10	S:S:F116	S:S:T114	29.5976	3.89	Yes	No	0	7	7
11	S:S:F116	S:S:I29	39.3838	7.54	Yes	Yes	0	7	4
12	R:R:F12	S:S:I29	40.9115	3.77	Yes	Yes	0	1	4
13	R:R:F12	S:S:P117	44.1829	7.22	Yes	No	0	1	4
14	R:R:F116	R:R:I29	38.5392	7.54	Yes	Yes	0	7	4
15	R:R:I29	S:S:F12	40.1103	3.77	Yes	Yes	0	4	1
16	R:R:P117	S:S:F12	43.4813	7.22	No	Yes	0	4	1
17	R:R:P117	R:R:V196	43.8979	1.77	No	No	0	4	1
18	R:R:V196	R:R:Y111	47.2504	2.52	No	No	0	1	5
19	R:R:Y106	R:R:Y111	47.0401	5.96	No	No	16	5	5
20	R:R:Y106	R:R:Y128	49.7495	3.97	No	Yes	0	5	8
21	R:R:Y101	R:R:Y128	55.9335	7.94	Yes	Yes	0	6	8
22	R:R:Y101	R:R:Y98	57.6001	6.95	Yes	Yes	0	6	6
23	S:S:P117	S:S:V196	44.5771	1.77	No	No	0	4	1
24	S:S:V196	S:S:Y111	47.7498	2.52	No	No	0	1	5
25	S:S:Y106	S:S:Y111	47.5458	4.96	No	No	25	5	5
26	S:S:Y106	S:S:Y128	50.2874	3.97	No	Yes	0	5	8
27	S:S:Y101	S:S:Y128	51.5679	7.94	Yes	Yes	0	6	8
28	S:S:Y101	S:S:Y98	53.3372	6.95	Yes	Yes	0	6	6
29	S:S:F55	S:S:Y98	54.6546	25.79	Yes	Yes	2	6	6
30	R:R:F55	R:R:Y98	58.8404	25.79	Yes	Yes	1	6	6
31	R:R:F55	R:R:R58	57.4042	8.55	Yes	Yes	1	6	9
32	R:R:I91	R:R:R58	54.2581	3.76	Yes	Yes	0	7	9
33	R:R:R58	R:R:T282	17.0611	2.59	Yes	No	0	9	5
34	R:R:L283	R:R:R58	35.259	7.29	No	Yes	0	8	9
35	R:R:A62	R:R:I91	28.2562	3.25	No	Yes	0	8	7
36	R:R:A62	R:R:L88	28.9233	3.15	No	Yes	0	8	9
37	R:R:I91	R:R:V286	28.0723	4.61	Yes	No	0	7	8
38	R:R:L88	R:R:V286	30.8452	2.98	Yes	No	0	9	8
39	R:R:L283	R:R:L287	35.4773	4.15	No	Yes	0	8	8
40	R:R:L287	S:S:L64	35.1362	2.77	Yes	Yes	12	8	5
41	S:S:L64	S:S:V68	85.2124	1.49	Yes	No	0	5	7
42	R:R:V68	S:S:V68	85.1803	6.41	No	No	0	7	7
43	R:R:L64	R:R:V68	85.2574	1.49	Yes	No	0	5	7
44	R:R:L64	S:S:T65	51.1014	5.9	Yes	No	11	5	7
45	R:R:L64	S:S:L287	34.0443	2.77	Yes	Yes	11	5	8
46	R:R:L66	R:R:L88	96.1739	2.77	No	Yes	0	5	9
47	R:R:L66	R:R:Q85	93.1706	6.65	No	Yes	7	5	5
48	R:R:M69	R:R:Q85	91.5289	12.23	No	Yes	7	8	5
49	R:R:M69	R:R:P290	91.4839	3.35	No	No	0	8	9
50	R:R:N84	R:R:P290	90.9685	3.26	Yes	No	0	9	9
51	R:R:N84	R:R:S293	82.8715	2.98	Yes	Yes	14	9	9
52	R:R:H94	R:R:Q135	12.6032	6.18	Yes	No	0	8	6
53	R:R:Q135	R:R:Y181	11.9144	2.25	No	Yes	0	6	7
54	R:R:F262	R:R:T282	14.4022	2.59	Yes	No	0	7	5
55	R:R:Q149	R:R:S293	82.2212	4.33	Yes	Yes	0	9	9
56	R:R:M218	R:R:Q149	52.2197	8.16	Yes	Yes	0	8	9
57	R:R:Q149	R:R:S292	30.3129	4.33	Yes	No	0	9	9
58	R:R:I150	R:R:M218	21.8795	4.37	Yes	Yes	0	8	8
59	R:R:I150	R:R:V221	10.6315	4.61	Yes	No	0	8	7
60	R:R:F217	R:R:L166	13.3072	4.87	Yes	No	0	6	7
61	R:R:L222	R:R:M218	24.4677	5.65	Yes	Yes	0	9	8
62	R:R:L222	R:R:W295	46.0253	4.56	Yes	Yes	0	9	9
63	R:R:K225	R:R:W295	19.9311	10.44	No	Yes	0	9	9
64	R:R:L222	R:R:S292	24.1659	3	Yes	No	0	9	9
65	R:R:L248	R:R:W295	13.3265	9.11	No	Yes	0	8	9
66	R:R:F244	R:R:L248	10.6572	7.31	No	No	3	9	8
67	R:R:L255	R:R:P258	11.0265	3.28	No	Yes	0	9	9
68	S:S:F55	S:S:R58	52.06	8.55	Yes	Yes	2	6	9
69	S:S:I91	S:S:R58	56.5284	3.76	Yes	Yes	0	7	9
70	S:S:R58	S:S:T282	17.1518	2.59	Yes	No	0	9	5
71	S:S:L283	S:S:L287	34.3952	4.15	No	Yes	0	8	8
72	S:S:L88	S:S:T65	51.3752	2.95	Yes	No	0	9	7
73	S:S:A62	S:S:L88	30.0914	3.15	No	Yes	0	8	9
74	S:S:L66	S:S:L88	100	2.77	No	Yes	0	5	9
75	S:S:L66	S:S:Q85	97.0393	6.65	No	Yes	8	5	5
76	S:S:M69	S:S:Q85	95.4321	12.23	No	Yes	8	8	5
77	S:S:M69	S:S:P290	95.4264	3.35	No	No	0	8	9
78	S:S:N84	S:S:P290	94.9247	3.26	Yes	No	0	9	9
79	S:S:N84	S:S:S293	86.928	2.98	Yes	Yes	23	9	9
80	S:S:L88	S:S:V286	32.0173	2.98	Yes	No	0	9	8
81	S:S:H94	S:S:Q135	20.2603	6.18	Yes	No	0	8	6
82	S:S:Q135	S:S:Y181	19.5827	2.25	No	Yes	0	6	7
83	S:S:F262	S:S:T282	14.4673	2.59	Yes	No	0	7	5
84	S:S:Q149	S:S:S293	86.3307	4.33	Yes	Yes	0	9	9
85	S:S:M218	S:S:Q149	54.1842	8.16	Yes	Yes	0	8	9
86	S:S:Q149	S:S:S292	32.523	4.33	Yes	No	0	9	9
87	S:S:I150	S:S:M218	21.6828	4.37	Yes	Yes	0	8	8
88	S:S:I150	S:S:V221	10.5351	4.61	Yes	No	0	8	7
89	S:S:F217	S:S:L166	13.1723	4.87	Yes	No	0	6	7
90	S:S:L222	S:S:M218	26.8272	5.65	Yes	Yes	0	9	8
91	S:S:L222	S:S:W295	50.7346	4.56	Yes	Yes	0	9	9
92	S:S:K225	S:S:W295	19.7818	10.44	No	Yes	0	9	9
93	S:S:L222	S:S:S292	26.4804	3	Yes	No	0	9	9
94	S:S:L226	S:S:W295	11.993	3.42	No	Yes	0	9	9
95	S:S:I249	S:S:L226	10.6668	2.85	No	No	0	9	9
96	S:S:L248	S:S:W295	13.2141	9.11	No	Yes	0	8	9
97	S:S:F244	S:S:L248	10.5673	7.31	No	No	4	9	8
98	S:S:L255	S:S:P258	10.9622	3.28	No	Yes	0	9	9
99	S:S:L283	S:S:R58	34.1752	7.29	No	Yes	0	8	9
100	R:R:T65	S:S:L64	49.9414	5.9	No	Yes	12	7	5
101	R:R:L88	R:R:T65	50.1838	2.95	Yes	No	0	9	7
102	S:S:A62	S:S:I91	29.4194	3.25	No	Yes	0	8	7
103	S:S:I91	S:S:V286	29.2364	4.61	Yes	No	0	7	8
104	R:R:H94	R:R:R58	12.5205	3.39	Yes	Yes	1	8	9
105	S:S:H94	S:S:R58	18.7622	3.39	Yes	Yes	2	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7QB9

PDB Summary
PDB	7QB9
Class	D1
SubFamily	Ste2-like
Type	STE2
SubType	STE2
Species	Saccharomyces Cerevisiae
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.1
Date	2022-03-16
D.O.I.	doi.org/10.1038/s41586-022-04498-3

Net Summary
I_min	1.77
Number of Linked Nodes	551
Number of Links	635
Number of Hubs	98
Number of Links mediated by Hubs	370
Number of Communities	30
Number of Nodes involved in Communities	128
Number of Links involved in Communities	150

Path Summary
Number Of Nodes in MetaPath	106
Number Of Links MetaPath	105
Number of Shortest Paths	317429
Length Of Smallest Path	3
Average Path Length	22.3895
Length of Longest Path	41
Minimum Path Strength	1.38
Average Path Strength	5.07521
Maximum Path Strength	21.0967
Minimum Path Correlation	0.7
Average Path Correlation	0.959674
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	44.584
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	52.8604
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of cellular process • sexual reproduction • response to stimulus • signaling • regulation of reproductive process • reproductive process • positive regulation of biological process • regulation of conjugation with cellular fusion • response to pheromone • cellular response to pheromone • cell communication • positive regulation of conjugation with cellular fusion • signal transduction • positive regulation of reproductive process • pheromone-dependent signal transduction involved in conjugation with cellular fusion • regulation of biological process • signal transduction involved in positive regulation of conjugation with cellular fusion • biological regulation • conjugation with cellular fusion • response to pheromone triggering conjugation with cellular fusion • cellular response to chemical stimulus • response to chemical • cellular process • reproductive process in single-celled organism • cytogamy • cell periphery • cellular anatomical structure • plasma membrane • membrane • G protein-coupled receptor homodimeric complex • protein-containing complex • plasma membrane protein complex • membrane protein complex • receptor complex • G protein-coupled receptor dimeric complex • plasma membrane signaling receptor complex • G protein-coupled receptor complex
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2 H:H:?3 H:H:?4
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P0CI39
Sequence	>7QB9_Chain_R A P S L S N L F Y D P T Y N P G Q S T I N Y T S I Y G N G S T I T F D E L Q G L V N S T V T Q A I M F G V R C G A A A L T L I V M W M T S R S R K T P I F I I N Q V S L F L I I L H S A L Y F K Y L L S N Y S S V T Y A L T G F P Q F I S R G D V H V Y G A T N I I Q V L L V A S I E T S L V F Q I K V I F T G D N F K R I G L M L T S I S F T L G I A T V T M Y F V S A V K G M I V T Y N D V S A T Q D K Y F N A S T I L L A S S I N F M S F V L V V K L I L A I R S R R F L G L K Q F D S F H I L L I M S C Q S L L V P S I I F I L A Y S L K P N Q G T D V L T T V A T L L A V L S L P L S S M W A T A A N N A S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	P0CI39
Sequence	>7QB9_Chain_S A P S L S N L F Y D P T Y N P G Q S T I N Y T S I Y G N G S T I T F D E L Q G L V N S T V T Q A I M F G V R C G A A A L T L I V M W M T S R S R K T P I F I I N Q V S L F L I I L H S A L Y F K Y L L S N Y S S V T Y A L T G F P Q F I S R G D V H V Y G A T N I I Q V L L V A S I E T S L V F Q I K V I F T G D N F K R I G L M L T S I S F T L G I A T V T M Y F V S A V K G M I V T Y N D V S A T Q D K Y F N A S T I L L A S S I N F M S F V L V V K L I L A I R S R R F L G L K Q F D S F H I L L I M S C Q S L L V P S I I F I L A Y S L K P N Q G T D V L T T V A T L L A V L S L P L S S M W A T A A N N A S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7AD3	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	Gi1/STE4/γ2	3.3	2020-12-09	doi.org/10.1038/s41586-020-2994-1
	7AD3 (No Gprot)	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-		3.3	2020-12-09	doi.org/10.1038/s41586-020-2994-1
	7QA8	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	Peptide	-	-	2.7	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QB9	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	-	-	-	3.1	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QBC	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	-	3.53	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QBI	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	-	3.46	2022-03-16	doi.org/10.1038/s41586-022-04498-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7QB9.zip

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