psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:M107	4.18	Yes	No	0	0	6
2	L:L:?1	R:R:G108	8.84	Yes	No	0	0	4
3	L:L:?1	R:R:I112	4.22	Yes	No	1	0	6
4	L:L:?1	R:R:F179	17.09	Yes	Yes	1	0	4
5	L:L:?1	R:R:Q181	4.91	Yes	Yes	1	0	3
6	L:L:?1	R:R:Y187	3.46	Yes	Yes	1	0	6
7	L:L:?1	R:R:V191	5.5	Yes	No	0	0	5
8	L:L:?1	R:R:H195	4.75	Yes	Yes	1	0	5
9	L:L:?1	R:R:W251	5.89	Yes	Yes	1	0	8
10	L:L:?1	R:R:L254	4.09	Yes	No	1	0	6
11	L:L:?1	R:R:N255	5.07	Yes	Yes	1	0	7
12	L:L:?1	R:R:Y281	3.46	Yes	Yes	1	0	5
13	R:R:L26	R:R:P23	9.85	No	No	0	2	2
14	R:R:I88	R:R:L30	4.28	No	No	0	4	5
15	R:R:L30	R:R:Y282	12.89	No	No	0	5	5
16	R:R:I38	R:R:L34	7.14	Yes	Yes	4	6	7
17	R:R:L34	R:R:Y81	5.86	Yes	Yes	4	7	7
18	R:R:L34	R:R:L85	6.92	Yes	No	0	7	6
19	R:R:I35	R:R:L85	4.28	No	No	0	4	6
20	R:R:F36	R:R:V40	7.87	No	No	0	4	5
21	R:R:F286	R:R:F36	4.29	Yes	No	0	4	4
22	R:R:T37	R:R:Y81	3.75	Yes	Yes	4	6	7
23	R:R:F286	R:R:T37	5.19	Yes	Yes	4	4	6
24	R:R:C289	R:R:T37	6.76	No	Yes	4	7	6
25	R:R:I38	R:R:Y81	4.84	Yes	Yes	4	6	7
26	R:R:I38	R:R:P82	3.39	Yes	No	0	6	8
27	R:R:C289	R:R:V40	6.83	No	No	0	7	5
28	R:R:D41	R:R:N45	8.08	Yes	Yes	2	7	9
29	R:R:D41	R:R:D73	7.98	Yes	Yes	2	7	9
30	R:R:A77	R:R:D41	4.63	No	Yes	0	6	7
31	R:R:D41	R:R:S288	4.42	Yes	No	0	7	9
32	R:R:A70	R:R:N45	4.69	No	Yes	0	9	9
33	R:R:D73	R:R:N45	8.08	Yes	Yes	2	9	9
34	R:R:L74	R:R:N45	9.61	No	Yes	0	7	9
35	R:R:A292	R:R:N45	4.69	No	Yes	0	9	9
36	R:R:L47	R:R:Y306	17.58	No	Yes	0	6	6
37	R:R:A70	R:R:V48	3.39	No	No	0	9	8
38	R:R:V48	R:R:Y306	3.79	No	Yes	0	8	6
39	R:R:E305	R:R:S51	5.75	Yes	No	0	6	8
40	R:R:S51	R:R:Y306	3.82	No	Yes	0	8	6
41	R:R:V52	R:R:V67	4.81	No	No	0	7	6
42	R:R:R59	R:R:Y53	4.12	No	No	0	7	3
43	R:R:E305	R:R:R54	3.49	Yes	No	0	6	4
44	R:R:L58	R:R:N55	13.73	No	No	0	8	5
45	R:R:K56	R:R:R59	13.61	No	No	0	6	7
46	R:R:L58	R:R:N63	4.12	No	No	0	8	8
47	R:R:N60	R:R:N63	8.17	No	No	0	7	8
48	R:R:A61	R:R:S144	3.42	No	No	0	6	7
49	R:R:G62	R:R:N124	5.09	No	Yes	0	7	8
50	R:R:F302	R:R:N63	6.04	No	No	0	8	8
51	R:R:I64	R:R:V148	6.14	No	Yes	0	5	7
52	R:R:F65	R:R:N124	6.04	Yes	Yes	5	7	8
53	R:R:F65	R:R:Y139	4.13	Yes	Yes	5	7	6
54	R:R:F65	R:R:Y147	4.13	Yes	Yes	5	7	5
55	R:R:F65	R:R:V148	5.24	Yes	Yes	0	7	7
56	R:R:I121	R:R:V66	6.14	Yes	No	0	9	8
57	R:R:N117	R:R:S68	5.96	No	No	0	7	9
58	R:R:D73	R:R:L69	4.07	Yes	Yes	2	9	9
59	R:R:L69	R:R:N117	4.12	Yes	No	0	9	7
60	R:R:I121	R:R:L69	4.28	Yes	Yes	2	9	9
61	R:R:L69	R:R:Y295	7.03	Yes	Yes	2	9	9
62	R:R:D73	R:R:S114	5.89	Yes	No	0	9	9
63	R:R:D73	R:R:N291	4.04	Yes	No	0	9	9
64	R:R:S110	R:R:V75	4.85	No	No	0	7	6
65	R:R:P80	R:R:V76	5.3	No	No	0	6	7
66	R:R:V76	R:R:Y81	13.88	No	Yes	0	7	7
67	R:R:S110	R:R:V76	8.08	No	No	0	7	7
68	R:R:P80	R:R:Y79	4.17	No	Yes	0	6	5
69	R:R:H99	R:R:Y79	17.42	No	Yes	0	5	5
70	R:R:V102	R:R:Y79	5.05	No	Yes	0	4	5
71	R:R:S103	R:R:Y79	5.09	No	Yes	0	5	5
72	R:R:L106	R:R:Y79	9.38	No	Yes	0	4	5
73	R:R:M107	R:R:P80	6.71	No	No	0	6	6
74	R:R:Y285	R:R:Y81	9.93	No	Yes	0	6	7
75	R:R:S288	R:R:Y81	7.63	No	Yes	0	9	7
76	R:R:L83	R:R:W93	3.42	Yes	Yes	3	6	8
77	R:R:L83	R:R:L95	4.15	Yes	No	3	6	7
78	R:R:H99	R:R:L83	9	No	Yes	3	5	6
79	R:R:S176	R:R:V84	8.08	No	No	0	4	6
80	R:R:S87	R:R:W93	4.94	No	Yes	0	5	8
81	R:R:F89	R:R:N90	7.25	No	No	0	4	4
82	R:R:N90	R:R:N91	5.45	No	No	0	4	4
83	R:R:G92	R:R:N90	3.39	No	No	0	4	4
84	R:R:C100	R:R:W93	6.53	No	Yes	3	9	8
85	R:R:W93	R:R:Y170	5.79	Yes	No	3	8	1
86	R:R:C177	R:R:W93	5.22	Yes	Yes	3	9	8
87	R:R:H99	R:R:L95	16.71	No	No	3	5	7
88	R:R:C100	R:R:C177	7.28	No	Yes	3	9	9
89	R:R:L168	R:R:Q101	6.65	No	No	0	5	6
90	R:R:G104	R:R:S103	3.71	No	No	0	5	5
91	R:R:C177	R:R:S103	3.44	Yes	No	0	9	5
92	R:R:G104	R:R:L168	3.42	No	No	0	5	5
93	R:R:F105	R:R:V159	5.24	No	No	0	6	7
94	R:R:F105	R:R:N162	4.83	No	Yes	0	6	4
95	R:R:F105	R:R:L163	3.65	No	No	0	6	6
96	R:R:L109	R:R:L156	8.3	No	No	0	5	3
97	R:R:L109	R:R:V159	8.94	No	No	0	5	7
98	R:R:V111	R:R:W251	7.36	No	Yes	0	7	8
99	R:R:F116	R:R:I112	7.54	No	No	0	5	6
100	R:R:H195	R:R:I112	7.95	Yes	No	1	5	6
101	R:R:G113	R:R:T155	3.64	No	Yes	0	7	8
102	R:R:I115	R:R:S114	4.64	Yes	No	0	7	9
103	R:R:H195	R:R:I115	11.93	Yes	Yes	1	5	7
104	R:R:I115	R:R:P199	3.39	Yes	No	0	7	9
105	R:R:F247	R:R:I115	3.77	Yes	Yes	0	9	7
106	R:R:I115	R:R:W251	5.87	Yes	Yes	1	7	8
107	R:R:F116	R:R:L154	4.87	No	No	0	5	4
108	R:R:F116	R:R:T155	5.19	No	Yes	0	5	8
109	R:R:I151	R:R:N117	5.66	No	No	0	7	7
110	R:R:F247	R:R:I118	6.28	Yes	No	0	9	9
111	R:R:I118	R:R:N291	7.08	No	No	0	9	9
112	R:R:I118	R:R:Y295	4.84	No	Yes	0	9	9
113	R:R:I121	R:R:R125	7.52	Yes	Yes	2	9	9
114	R:R:I121	R:R:Y295	6.04	Yes	Yes	2	9	9
115	R:R:A122	R:R:Y207	5.34	No	Yes	0	9	9
116	R:R:N124	R:R:Y135	8.14	Yes	No	5	8	5
117	R:R:N124	R:R:Y139	12.79	Yes	Yes	5	8	6
118	R:R:R125	R:R:Y207	8.23	Yes	Yes	2	9	9
119	R:R:F244	R:R:R125	9.62	Yes	Yes	2	8	9
120	R:R:R125	R:R:Y295	8.23	Yes	Yes	2	9	9
121	R:R:C130	R:R:Y126	8.06	No	Yes	0	7	8
122	R:R:H131	R:R:Y126	8.71	No	Yes	0	6	8
123	R:R:C206	R:R:Y126	9.41	No	Yes	0	7	8
124	R:R:R209	R:R:Y126	7.2	No	Yes	0	4	8
125	R:R:Y128	R:R:Y135	19.86	No	No	0	8	5
126	R:R:I129	R:R:I210	5.89	No	No	0	8	8
127	R:R:C130	R:R:L213	4.76	No	No	0	7	5
128	R:R:Y135	R:R:Y139	8.94	No	Yes	5	5	6
129	R:R:Y139	R:R:Y147	4.96	Yes	Yes	5	6	5
130	R:R:N143	R:R:S140	8.94	No	No	0	4	7
131	R:R:N143	R:R:Y147	3.49	No	Yes	0	4	5
132	R:R:T155	R:R:W152	8.49	Yes	No	0	8	9
133	R:R:L156	R:R:T155	4.42	No	Yes	0	3	8
134	R:R:P161	R:R:R164	4.32	No	No	0	6	4
135	R:R:P161	R:R:Y187	9.74	No	Yes	0	6	6
136	R:R:N162	R:R:T167	8.77	Yes	Yes	1	4	4
137	R:R:L168	R:R:N162	12.36	No	Yes	0	5	4
138	R:R:N162	R:R:Y187	4.65	Yes	Yes	1	4	6
139	R:R:F179	R:R:T167	7.78	Yes	Yes	1	4	4
140	R:R:T167	R:R:Y187	8.74	Yes	Yes	1	4	6
141	R:R:C177	R:R:Y170	4.03	Yes	No	3	9	1
142	R:R:D171	R:R:I174	4.2	No	No	0	4	1
143	R:R:E274	R:R:R173	15.12	No	No	1	3	5
144	R:R:F277	R:R:R173	19.24	Yes	No	1	3	5
145	R:R:F277	R:R:I174	3.77	Yes	No	1	3	1
146	R:R:I174	R:R:Y281	7.25	No	Yes	1	1	5
147	R:R:T178	R:R:Y281	4.99	No	Yes	0	4	5
148	R:R:F179	R:R:Q181	5.86	Yes	Yes	1	4	3
149	R:R:F179	R:R:Y187	11.35	Yes	Yes	1	4	6
150	R:R:F179	R:R:T188	3.89	Yes	No	1	4	5
151	R:R:Q181	R:R:T188	4.25	Yes	No	1	3	5
152	R:R:Q181	R:R:V261	7.16	Yes	No	0	3	3
153	R:R:S184	R:R:Y187	5.09	No	Yes	0	4	6
154	R:R:N255	R:R:V192	4.43	Yes	No	0	7	5
155	R:R:L259	R:R:V192	4.47	No	No	0	5	5
156	R:R:L197	R:R:V193	4.47	No	No	0	4	5
157	R:R:H195	R:R:W251	6.35	Yes	Yes	1	5	8
158	R:R:A252	R:R:F196	4.16	No	No	0	5	8
159	R:R:F196	R:R:N255	14.5	No	Yes	0	8	7
160	R:R:P199	R:R:V198	5.3	No	No	0	9	6
161	R:R:I201	R:R:M200	4.37	No	No	0	3	7
162	R:R:V203	R:R:Y207	3.79	No	Yes	0	8	9
163	R:R:F247	R:R:V203	5.24	Yes	No	0	9	8
164	R:R:F205	R:R:R209	11.76	No	No	0	4	4
165	R:R:F244	R:R:Y207	16.5	Yes	Yes	2	8	9
166	R:R:I212	R:R:W211	3.52	No	Yes	0	3	5
167	R:R:L215	R:R:W211	10.25	No	Yes	0	5	5
168	R:R:F237	R:R:W211	8.02	Yes	Yes	0	6	5
169	R:R:Q216	R:R:R220	3.5	No	No	0	4	4
170	R:R:K222	R:R:R218	7.43	No	No	0	3	4
171	R:R:K222	R:R:V221	7.59	No	No	0	3	5
172	R:R:F234	R:R:F237	5.36	No	Yes	0	4	6
173	R:R:R235	R:R:T239	3.88	No	No	0	8	8
174	R:R:M240	R:R:N236	5.61	Yes	No	0	7	7
175	R:R:F237	R:R:F241	12.86	Yes	No	0	6	6
176	R:R:V238	R:R:V242	8.02	No	No	0	6	6
177	R:R:F241	R:R:V245	5.24	No	No	0	6	5
178	R:R:F244	R:R:V243	5.24	Yes	No	0	8	8
179	R:R:L298	R:R:V243	4.47	No	No	0	6	8
180	R:R:F244	R:R:Y295	9.28	Yes	Yes	2	8	9
181	R:R:L246	R:R:L290	4.15	No	No	0	6	6
182	R:R:A248	R:R:F247	4.16	No	Yes	0	6	9
183	R:R:F247	R:R:N287	3.62	Yes	No	0	9	9
184	R:R:N255	R:R:W251	4.52	Yes	Yes	1	7	8
185	R:R:A284	R:R:W251	7.78	No	Yes	0	7	8
186	R:R:N287	R:R:W251	13.56	No	Yes	0	9	8
187	R:R:M283	R:R:P253	8.39	No	No	0	7	9
188	R:R:L254	R:R:S280	6.01	No	No	0	6	7
189	R:R:L254	R:R:Y281	22.27	No	Yes	1	6	5
190	R:R:I257	R:R:I272	5.89	No	No	1	5	5
191	R:R:F277	R:R:I257	3.77	Yes	No	1	3	5
192	R:R:P270	R:R:V269	3.53	No	No	0	3	3
193	R:R:I272	R:R:P273	3.39	No	No	0	5	4
194	R:R:F277	R:R:I272	3.77	Yes	No	1	3	5
195	R:R:E274	R:R:F277	3.5	No	Yes	1	3	3
196	R:R:E274	R:R:V278	4.28	No	No	0	3	4
197	R:R:F277	R:R:Y281	5.16	Yes	Yes	1	3	5
198	R:R:Y281	R:R:Y285	4.96	Yes	No	0	5	6
199	R:R:Y282	R:R:Y285	7.94	No	No	0	5	6
200	R:R:C289	R:R:F286	8.38	No	Yes	4	7	4
201	R:R:F286	R:R:L290	4.87	Yes	No	0	4	6
202	R:R:N287	R:R:N291	12.26	No	No	0	9	9
203	R:R:I294	R:R:Y295	6.04	No	Yes	0	8	9
204	R:R:L297	R:R:Y306	4.69	No	Yes	0	6	6
205	R:R:N299	R:R:Q300	5.28	No	No	6	8	5
206	R:R:N299	R:R:N301	6.81	No	No	6	8	6
207	R:R:F302	R:R:N299	9.67	No	No	0	8	8
208	R:R:N301	R:R:Q300	5.28	No	No	6	6	5
209	R:R:Q300	R:R:R303	3.5	No	No	0	5	9
210	R:R:E305	R:R:R308	6.98	Yes	No	0	6	5
211	R:R:E305	R:R:I309	4.1	Yes	No	0	6	6
212	R:R:R308	R:R:S312	5.27	No	No	0	5	5
213	R:R:A262	R:R:I189	3.25	No	No	0	4	5
214	R:R:S68	R:R:V148	3.23	No	Yes	0	9	7
215	R:R:I64	R:R:S144	3.1	No	No	0	5	7
216	R:R:I293	R:R:V40	3.07	No	No	0	6	5
217	R:R:M268	R:R:S263	3.07	No	No	0	1	4
218	R:R:M268	R:R:S267	3.07	No	No	0	1	1
219	R:R:I123	R:R:T119	3.04	No	No	0	6	7
220	R:R:I202	R:R:T119	3.04	No	No	0	6	7
221	R:R:A180	R:R:Q169	3.03	No	No	0	3	1
222	R:R:M240	R:R:T239	3.01	Yes	No	0	7	8
223	R:R:L34	R:R:V84	2.98	Yes	No	0	7	6
224	R:R:L43	R:R:V39	2.98	No	No	0	3	5
225	R:R:L149	R:R:V148	2.98	No	Yes	0	3	7
226	R:R:C127	R:R:H131	2.95	No	No	0	5	6
227	R:R:I38	R:R:I42	2.94	Yes	No	0	6	6
228	R:R:G296	R:R:Y306	2.9	No	Yes	0	6	6
229	R:R:I249	R:R:L246	2.85	No	No	0	5	6
230	R:R:K134	R:R:L138	2.82	No	No	0	4	4
231	R:R:K137	R:R:L138	2.82	No	No	0	4	4
232	R:R:G96	R:R:W93	2.81	No	Yes	0	7	8
233	R:R:K57	R:R:N55	2.8	No	No	0	5	5
234	R:R:L160	R:R:L163	2.77	No	No	0	4	6
235	R:R:C127	R:R:Y139	2.69	No	Yes	0	5	6
236	R:R:C146	R:R:Y147	2.69	No	Yes	0	3	5
237	R:R:F302	R:R:V66	2.62	No	No	0	8	8
238	R:R:F194	R:R:V193	2.62	No	No	0	4	5
239	R:R:R220	R:R:V217	2.62	No	No	0	4	5
240	R:R:F237	R:R:V242	2.62	Yes	No	0	6	6
241	R:R:R308	R:R:V311	2.62	No	No	0	5	3
242	R:R:A72	R:R:W152	2.59	No	No	0	8	9
243	R:R:F241	R:R:I204	2.51	No	No	0	6	4
244	R:R:I212	R:R:R209	2.51	No	No	0	3	4
245	R:R:F196	R:R:M200	2.49	No	No	0	8	7
246	R:R:I88	R:R:Y175	2.42	No	No	0	4	5
247	R:R:I123	R:R:Y139	2.42	No	Yes	0	6	6
248	R:R:L138	R:R:Y139	2.34	No	Yes	0	4	6
249	R:R:M240	R:R:W211	2.33	Yes	Yes	0	7	5
250	R:R:A252	R:R:P253	1.87	No	No	0	5	9
251	R:R:G258	R:R:V261	1.84	No	No	0	4	3
252	R:R:P265	R:R:V269	1.77	No	No	0	3	3
253	R:R:G120	R:R:I151	1.76	No	No	0	6	7
254	R:R:G44	R:R:L43	1.71	No	No	0	7	3
255	R:R:G44	R:R:L47	1.71	No	No	0	7	6
256	R:R:A165	R:R:T167	1.68	No	Yes	0	5	4
257	R:R:A262	R:R:T188	1.68	No	No	0	4	5
258	R:R:K222	R:R:P223	1.67	No	No	0	3	3
259	R:R:C130	R:R:I210	1.64	No	No	0	7	8
260	R:R:C250	R:R:I249	1.64	No	No	0	8	5
261	R:R:L276	R:R:P273	1.64	No	No	0	5	4
262	R:R:A70	R:R:I49	1.62	No	No	0	9	7
263	R:R:S184	R:R:V183	1.62	No	No	0	4	1
264	R:R:D171	R:R:P172	1.61	No	No	0	4	3
265	R:R:D264	R:R:P265	1.61	No	No	0	4	3
266	R:R:A279	R:R:M283	1.61	No	No	0	5	7
267	R:R:V67	R:R:V71	1.6	No	No	0	6	6
268	R:R:V71	R:R:V75	1.6	No	No	0	6	6
269	R:R:V192	R:R:V193	1.6	No	No	0	5	5
270	R:R:T37	R:R:V33	1.59	Yes	No	0	6	4
271	R:R:A31	R:R:L85	1.58	No	No	0	5	6
272	R:R:I310	R:R:V311	1.54	No	No	0	7	3
273	R:R:M240	R:R:V214	1.52	Yes	No	0	7	8
274	R:R:L145	R:R:V148	1.49	No	Yes	0	1	7
275	R:R:D264	R:R:S185	1.47	No	No	0	4	3
276	R:R:D264	R:R:S267	1.47	No	No	0	4	1
277	R:R:G92	R:R:Y170	1.45	No	No	0	4	1
278	R:R:I204	R:R:L208	1.43	No	No	0	4	3
279	R:R:L83	R:R:M86	1.41	Yes	No	0	6	4
280	R:R:K134	R:R:L133	1.41	No	No	0	4	6
281	R:R:M86	R:R:N94	1.4	No	No	0	4	2
282	R:R:L213	R:R:Q216	1.33	No	No	0	5	4
283	R:R:D171	R:R:Q169	1.31	No	No	0	4	1
284	R:R:R173	R:R:V269	1.31	No	No	0	5	3
285	R:R:R218	R:R:V217	1.31	No	No	0	4	5
286	R:R:I310	R:R:R307	1.25	No	No	0	7	4
287	R:R:M268	R:R:R271	1.24	No	No	0	1	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	5.955	12	1	0
2	R:R:L34	5.725	4	4	7
3	R:R:T37	4.3225	4	4	6
4	R:R:I38	4.5775	4	4	6
5	R:R:D41	6.2775	4	2	7
6	R:R:N45	7.03	5	2	9
7	R:R:F65	4.885	4	5	7
8	R:R:L69	4.875	4	2	9
9	R:R:D73	6.012	5	2	9
10	R:R:Y79	8.222	5	0	5
11	R:R:Y81	7.64833	6	4	7
12	R:R:L83	4.495	4	3	6
13	R:R:W93	4.785	6	3	8
14	R:R:I115	5.92	5	1	7
15	R:R:I121	5.995	4	2	9
16	R:R:N124	8.015	4	5	8
17	R:R:R125	8.4	4	2	9
18	R:R:Y126	8.345	4	0	8
19	R:R:Y139	5.46714	7	5	6
20	R:R:Y147	3.8175	4	5	5
21	R:R:V148	3.816	5	0	7
22	R:R:T155	5.435	4	0	8
23	R:R:N162	7.6525	4	1	4
24	R:R:T167	6.7425	4	1	4
25	R:R:C177	4.9925	4	3	9
26	R:R:F179	9.194	5	1	4
27	R:R:Q181	5.545	4	1	3
28	R:R:Y187	7.17167	6	1	6
29	R:R:H195	7.745	4	1	5
30	R:R:Y207	8.465	4	2	9
31	R:R:W211	6.03	4	0	5
32	R:R:F237	7.215	4	0	6
33	R:R:M240	3.1175	4	0	7
34	R:R:F244	10.16	4	2	8
35	R:R:F247	4.614	5	0	9
36	R:R:W251	7.33286	7	1	8
37	R:R:N255	7.13	4	1	7
38	R:R:F277	6.535	6	1	3
39	R:R:Y281	8.015	6	1	5
40	R:R:F286	5.6825	4	4	4
41	R:R:Y295	6.91	6	2	9
42	R:R:E305	5.08	4	0	6
43	R:R:Y306	6.556	5	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y281	47.8775	3.46	Yes	Yes	1	0	5
2	R:R:Y281	R:R:Y285	21.1368	4.96	Yes	No	0	5	6
3	R:R:Y285	R:R:Y81	22.174	9.93	No	Yes	0	6	7
4	R:R:T37	R:R:Y81	12.2005	3.75	Yes	Yes	4	6	7
5	L:L:?1	R:R:H195	30.3626	4.75	Yes	Yes	1	0	5
6	R:R:H195	R:R:I115	35.1664	11.93	Yes	Yes	1	5	7
7	R:R:I115	R:R:S114	53.425	4.64	Yes	No	0	7	9
8	R:R:D73	R:R:S114	53.1677	5.89	Yes	No	0	9	9
9	R:R:D41	R:R:D73	30.1214	7.98	Yes	Yes	2	7	9
10	L:L:?1	R:R:W251	65.4084	5.89	Yes	Yes	1	0	8
11	R:R:I115	R:R:W251	38.4909	5.87	Yes	Yes	1	7	8
12	R:R:N287	R:R:W251	43.7048	13.56	No	Yes	0	9	8
13	R:R:N287	R:R:N291	34.2861	12.26	No	No	0	9	9
14	R:R:D73	R:R:N291	28.8913	4.04	Yes	No	0	9	9
15	R:R:S288	R:R:Y81	36.5453	7.63	No	Yes	0	9	7
16	R:R:D41	R:R:S288	36.5292	4.42	Yes	No	0	7	9
17	R:R:D73	R:R:N45	21.2454	8.08	Yes	Yes	2	9	9
18	R:R:A70	R:R:N45	25.0482	4.69	No	Yes	0	9	9
19	R:R:A70	R:R:V48	22.5157	3.39	No	No	0	9	8
20	R:R:V48	R:R:Y306	21.2253	3.79	No	Yes	0	8	6
21	R:R:S51	R:R:Y306	12.3694	3.82	No	Yes	0	8	6
22	R:R:E305	R:R:S51	11.0267	5.75	Yes	No	0	6	8
23	L:L:?1	R:R:M107	15.927	4.18	Yes	No	0	0	6
24	R:R:M107	R:R:P80	14.3713	6.71	No	No	0	6	6
25	R:R:P80	R:R:V76	15.7702	5.3	No	No	0	6	7
26	R:R:D73	R:R:L69	100	4.07	Yes	Yes	2	9	9
27	R:R:I121	R:R:L69	20.2565	4.28	Yes	Yes	2	9	9
28	R:R:I121	R:R:V66	30.3505	6.14	Yes	No	0	9	8
29	R:R:F302	R:R:V66	27.5888	2.62	No	No	0	8	8
30	R:R:F302	R:R:N63	14.1019	6.04	No	No	0	8	8
31	R:R:F247	R:R:I115	20.2525	3.77	Yes	Yes	0	9	7
32	R:R:F247	R:R:I118	19.7942	6.28	Yes	No	0	9	9
33	R:R:I118	R:R:Y295	24.196	4.84	No	Yes	0	9	9
34	R:R:I121	R:R:Y295	14.2547	6.04	Yes	Yes	2	9	9
35	R:R:F247	R:R:N287	10.7051	3.62	Yes	No	0	9	9
36	R:R:L69	R:R:N117	87.8598	4.12	Yes	No	0	9	7
37	R:R:N117	R:R:S68	84.2539	5.96	No	No	0	7	9
38	R:R:S68	R:R:V148	83.0359	3.23	No	Yes	0	9	7
39	R:R:F65	R:R:V148	75.5588	5.24	Yes	Yes	0	7	7
40	R:R:F65	R:R:Y139	62.5864	4.13	Yes	Yes	5	7	6
41	R:R:P80	R:R:Y79	24.9879	4.17	No	Yes	0	6	5
42	R:R:S103	R:R:Y79	13.2377	5.09	No	Yes	0	5	5
43	R:R:C177	R:R:S103	12.1643	3.44	Yes	No	0	9	5
44	L:L:?1	R:R:Y187	29.8119	3.46	Yes	Yes	1	0	6
45	R:R:N162	R:R:Y187	16.6707	4.65	Yes	Yes	1	4	6
46	R:R:C127	R:R:Y139	50.2372	2.69	No	Yes	0	5	6
47	R:R:C127	R:R:H131	48.8181	2.95	No	No	0	5	6
48	R:R:H131	R:R:Y126	47.3911	8.71	No	Yes	0	6	8
49	R:R:C130	R:R:Y126	17.7842	8.06	No	Yes	0	7	8
50	R:R:R209	R:R:Y126	28.2963	7.2	No	Yes	0	4	8
51	R:R:C130	R:R:L213	12.9683	4.76	No	No	0	7	5
52	L:L:?1	R:R:F179	12.104	17.09	Yes	Yes	1	0	4
53	R:R:I174	R:R:Y281	10.7453	7.25	No	Yes	1	1	5
54	R:R:F277	R:R:Y281	37.699	5.16	Yes	Yes	1	3	5
55	L:L:?1	R:R:Q181	12.6226	4.91	Yes	Yes	1	0	3
56	R:R:F196	R:R:N255	11.6739	14.5	No	Yes	0	8	7
57	R:R:I212	R:R:R209	25.4181	2.51	No	No	0	3	4
58	R:R:I212	R:R:W211	23.8624	3.52	No	Yes	0	3	5
59	R:R:F237	R:R:W211	12.9402	8.02	Yes	Yes	0	6	5
60	R:R:L213	R:R:Q216	11.5613	1.33	No	No	0	5	4
61	R:R:F277	R:R:R173	22.3589	19.24	Yes	No	1	3	5
62	R:R:R173	R:R:V269	20.4333	1.31	No	No	0	5	3
63	R:R:F302	R:R:N299	11.3	9.67	No	No	0	8	8
64	R:R:P265	R:R:V269	16.1481	1.77	No	No	0	3	3
65	R:R:D264	R:R:P265	13.8648	1.61	No	No	0	4	3
66	R:R:V76	R:R:Y81	17.2737	13.88	No	Yes	0	7	7
67	R:R:N255	R:R:W251	14.8899	4.52	Yes	Yes	1	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:M107	4.18	1	Yes	No	0	6	0	1
L:L:?1	R:R:G108	8.84	1	Yes	No	0	4	0	1
L:L:?1	R:R:I112	4.22	1	Yes	No	0	6	0	1
L:L:?1	R:R:F179	17.09	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:Q181	4.91	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:Y187	3.46	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:V191	5.5	1	Yes	No	0	5	0	1
L:L:?1	R:R:H195	4.75	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:W251	5.89	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:L254	4.09	1	Yes	No	0	6	0	1
L:L:?1	R:R:N255	5.07	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:Y281	3.46	1	Yes	Yes	0	5	0	1
R:R:M107	R:R:P80	6.71	0	No	No	6	6	1	2
R:R:V111	R:R:W251	7.36	0	No	Yes	7	8	2	1
R:R:F116	R:R:I112	7.54	0	No	No	5	6	2	1
R:R:H195	R:R:I112	7.95	1	Yes	No	5	6	1	1
R:R:H195	R:R:I115	11.93	1	Yes	Yes	5	7	1	2
R:R:I115	R:R:W251	5.87	1	Yes	Yes	7	8	2	1
R:R:P161	R:R:Y187	9.74	0	No	Yes	6	6	2	1
R:R:N162	R:R:T167	8.77	1	Yes	Yes	4	4	2	2
R:R:N162	R:R:Y187	4.65	1	Yes	Yes	4	6	2	1
R:R:F179	R:R:T167	7.78	1	Yes	Yes	4	4	1	2
R:R:T167	R:R:Y187	8.74	1	Yes	Yes	4	6	2	1
R:R:F277	R:R:I174	3.77	1	Yes	No	3	1	2	2
R:R:I174	R:R:Y281	7.25	1	No	Yes	1	5	2	1
R:R:T178	R:R:Y281	4.99	0	No	Yes	4	5	2	1
R:R:F179	R:R:Q181	5.86	1	Yes	Yes	4	3	1	1
R:R:F179	R:R:Y187	11.35	1	Yes	Yes	4	6	1	1
R:R:F179	R:R:T188	3.89	1	Yes	No	4	5	1	2
R:R:Q181	R:R:T188	4.25	1	Yes	No	3	5	1	2
R:R:Q181	R:R:V261	7.16	1	Yes	No	3	3	1	2
R:R:S184	R:R:Y187	5.09	0	No	Yes	4	6	2	1
R:R:N255	R:R:V192	4.43	1	Yes	No	7	5	1	2
R:R:H195	R:R:W251	6.35	1	Yes	Yes	5	8	1	1
R:R:F196	R:R:N255	14.5	0	No	Yes	8	7	2	1
R:R:N255	R:R:W251	4.52	1	Yes	Yes	7	8	1	1
R:R:A284	R:R:W251	7.78	0	No	Yes	7	8	2	1
R:R:N287	R:R:W251	13.56	0	No	Yes	9	8	2	1
R:R:L254	R:R:S280	6.01	1	No	No	6	7	1	2
R:R:L254	R:R:Y281	22.27	1	No	Yes	6	5	1	1
R:R:F277	R:R:Y281	5.16	1	Yes	Yes	3	5	2	1
R:R:Y281	R:R:Y285	4.96	1	Yes	No	5	6	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7VGY_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.39
Number of Linked Nodes	252
Number of Links	287
Number of Hubs	43
Number of Links mediated by Hubs	159
Number of Communities	6
Number of Nodes involved in Communities	50
Number of Links involved in Communities	71

Path Summary
Number Of Nodes in MetaPath	68
Number Of Links MetaPath	67
Number of Shortest Paths	55326
Length Of Smallest Path	3
Average Path Length	13.1334
Length of Longest Path	31
Minimum Path Strength	1.395
Average Path Strength	5.70039
Maximum Path Strength	17.065
Minimum Path Correlation	0.7
Average Path Correlation	0.921471
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	45.5028
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.7808
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• rhythmic process • circadian rhythm • behavior • multicellular organismal process • reproductive process • multicellular organismal reproductive process • reproductive behavior • mating behavior • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • protein-containing complex • receptor complex • cell periphery • cellular anatomical structure • plasma membrane • membrane • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell cortex • cytoplasm • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • cytoskeletal protein binding • spectrin binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to stress • response to hypoxia • response to stress • response to oxygen levels • response to abiotic stimulus • cell population proliferation • phospholipase C-activating G protein-coupled receptor signaling pathway • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • dendrite • dendritic tree • neuron projection • non-motile cilium • 9+0 non-motile cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• G protein-coupled receptor-like • Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	ML2
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	ML2
Name	N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
Synonyms	N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
Identifier
Formula	C13 H15 I N2 O2
Molecular Weight	358.175
SMILES
PubChem	115348
Formal Charge	0
Total Atoms	33
Total Chiral Atoms	0
Total Bonds	34
Total Aromatic Bonds	10


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P48039
Sequence	>7VGY_nogp_Chain_R P S W L A S A L A C V L I F T I V V D I L G N L L V I L S V Y R N K K L R N A G N I F V V S L A V A D L V V A I Y P Y P L V L M S I F N N G W N L G Y L H C Q V S G F L M G L S V I G S I F N I T G I A I N R Y C Y I C H S L K Y D K L Y S S K N S L C Y V L L I W L L T L A A V L P N L R A G T L Q Y D P R I Y S C T F A Q S V S S A Y T I A V V V F H F L V P M I I V I F C Y L R I W I L V L Q V R Q R V K P F R N F V T M F V V F V L F A I C W A P L N F I G L A V A S D P A S M V P R I P E W L F V A S Y Y M A Y F N S C L N A I I Y G L L N Q N F R K E Y R R I I V S L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7VGY	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Iodomelatonin	-	Gi1/β1/γ2	3.1	2022-03-02	doi.org/10.1038/s41467-022-28111-3
	7VGY (No Gprot)	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Iodomelatonin	-		3.1	2022-03-02	doi.org/10.1038/s41467-022-28111-3
	7VGZ	A	Melatonin	Melatonin	MT₁	Homo sapiens	Remalteon	-	Gi1/β1/γ2	3.3	2022-03-02	doi.org/10.1038/s41467-022-28111-3
	7VGZ (No Gprot)	A	Melatonin	Melatonin	MT₁	Homo sapiens	Remalteon	-		3.3	2022-03-02	doi.org/10.1038/s41467-022-28111-3
	6ME2	A	Melatonin	Melatonin	MT₁	Homo sapiens	Ramelteon	-	-	2.8	2019-04-24	doi.org/10.1038/s41586-019-1141-3
	6ME3	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Phenylmelatonin	-	-	2.9	2019-04-24	doi.org/10.1038/s41586-019-1141-3
	6ME4	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Iodomelatonin	-	-	3.2	2019-04-24	doi.org/10.1038/s41586-019-1141-3
	6ME5	A	Melatonin	Melatonin	MT₁	Homo sapiens	Agomelatine	-	-	3.2	2019-04-24	doi.org/10.1038/s41586-019-1141-3
	7DB6	A	Melatonin	Melatonin	MT₁	Homo sapiens	Ramelteon	-	Gi1/β1/γ2	3.3	2021-08-18	doi.org/10.1038/s41594-021-00634-1
	7DB6 (No Gprot)	A	Melatonin	Melatonin	MT₁	Homo sapiens	Ramelteon	-		3.3	2021-08-18	doi.org/10.1038/s41594-021-00634-1
	6PS8	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Phenylmelatonin	-	-	3.3	2019-11-13	doi.org/10.1107/S2052252519013137

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