psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G158	R:R:I157	3.53	No	No	0	3	1
2	R:R:I157	R:R:W160	11.74	No	No	5	1	3
3	R:R:I157	R:R:P460	3.39	No	No	5	1	5
4	R:R:F159	R:R:L176	6.09	No	No	0	4	5
5	R:R:F159	R:R:V450	7.87	No	No	0	4	3
6	R:R:P460	R:R:W160	5.4	No	No	5	5	3
7	R:R:C161	R:R:P162	3.77	No	No	0	9	6
8	R:R:C161	R:R:K166	4.85	No	No	0	9	4
9	R:R:C161	R:R:C181	7.28	No	No	0	9	9
10	R:R:L165	R:R:P162	14.78	No	No	0	7	6
11	R:R:I459	R:R:P162	6.77	Yes	No	0	6	6
12	R:R:Q171	R:R:T167	12.76	No	No	0	3	4
13	R:R:Q180	R:R:T167	7.09	No	No	0	5	4
14	R:R:L275	R:R:Q171	3.99	Yes	No	0	8	3
15	R:R:Q171	R:R:Q278	8.96	No	No	0	3	6
16	R:R:F175	R:R:Y173	7.22	No	No	0	6	6
17	R:R:L275	R:R:Y173	3.52	Yes	No	0	8	6
18	R:R:D363	R:R:Y173	3.45	No	No	0	7	6
19	R:R:C181	R:R:F175	4.19	No	No	0	9	6
20	R:R:E446	R:R:F175	4.66	No	No	0	5	6
21	R:R:E446	R:R:L176	11.93	No	No	0	5	5
22	R:R:C181	R:R:I178	3.27	No	No	0	9	5
23	R:R:A182	R:R:T272	3.36	No	No	0	7	6
24	R:R:A182	R:R:L275	3.15	No	Yes	0	7	8
25	R:R:P183	R:R:V273	5.3	No	No	0	6	6
26	R:R:L275	R:R:P183	3.28	Yes	No	0	8	6
27	R:R:P183	R:R:Y362	8.34	No	No	0	6	5
28	R:R:P184	R:R:P186	3.9	No	No	0	6	4
29	R:R:P184	R:R:W449	6.76	No	Yes	0	6	6
30	R:R:C185	R:R:P186	3.77	No	No	0	9	4
31	R:R:C185	R:R:C260	7.28	No	No	0	9	9
32	R:R:C185	R:R:D271	3.11	No	No	0	9	4
33	R:R:L195	R:R:N187	4.12	No	No	0	7	6
34	R:R:N187	R:R:N352	4.09	No	No	0	6	7
35	R:R:I353	R:R:N187	8.5	Yes	No	0	7	6
36	R:R:M188	R:R:Y189	3.59	No	No	0	7	5
37	R:R:M188	R:R:W449	8.14	No	Yes	0	7	6
38	R:R:P471	R:R:Y189	11.13	Yes	No	0	8	5
39	R:R:E194	R:R:F190	3.5	Yes	Yes	1	7	7
40	R:R:F190	R:R:I353	3.77	Yes	Yes	1	7	7
41	R:R:F190	R:R:L473	8.53	Yes	No	1	7	5
42	R:R:F190	R:R:F476	7.5	Yes	No	0	7	7
43	R:R:D193	R:R:E196	9.09	No	No	0	3	1
44	R:R:E194	R:R:L473	3.98	Yes	No	1	7	5
45	R:R:F197	R:R:S200	5.28	No	No	0	6	4
46	R:R:F252	R:R:K199	3.72	No	No	0	6	7
47	R:R:D256	R:R:K199	9.68	No	No	0	6	7
48	R:R:F201	R:R:M477	6.22	No	No	0	8	7
49	R:R:F201	R:R:L481	7.31	No	No	0	8	7
50	R:R:I202	R:R:Y248	6.04	Yes	Yes	1	7	7
51	R:R:F252	R:R:I202	5.02	No	Yes	0	6	7
52	R:R:I202	R:R:S354	3.1	Yes	Yes	1	7	8
53	R:R:I202	R:R:Y480	3.63	Yes	No	1	7	7
54	R:R:F252	R:R:G203	4.52	No	No	0	6	5
55	R:R:L484	R:R:V205	4.47	Yes	No	0	8	5
56	R:R:S206	R:R:Y248	3.82	No	Yes	0	8	7
57	R:R:F249	R:R:S206	9.25	No	No	0	5	8
58	R:R:C209	R:R:S245	6.89	No	No	1	8	8
59	R:R:C209	R:R:L484	7.94	No	Yes	1	8	8
60	R:R:L210	R:R:S245	3	No	No	0	5	8
61	R:R:L210	R:R:L246	5.54	No	No	0	5	4
62	R:R:A212	R:R:I488	3.25	No	No	0	8	8
63	R:R:A212	R:R:V491	3.39	No	No	0	8	8
64	R:R:T213	R:R:T216	3.14	No	Yes	0	8	8
65	R:R:S242	R:R:T213	9.59	No	No	0	5	8
66	R:R:T216	R:R:T219	3.14	Yes	No	6	8	9
67	R:R:S238	R:R:T216	7.99	No	Yes	0	8	8
68	R:R:A490	R:R:T216	3.36	No	Yes	0	8	8
69	R:R:T216	R:R:V494	6.35	Yes	No	6	8	7
70	R:R:F217	R:R:V239	7.87	No	No	0	6	5
71	R:R:T219	R:R:V494	6.35	No	No	6	9	7
72	R:R:F220	R:R:I235	12.56	No	Yes	0	9	8
73	R:R:D223	R:R:I222	4.2	No	No	0	8	8
74	R:R:D223	R:R:F227	5.97	No	No	0	8	8
75	R:R:E321	R:R:R225	9.3	No	No	0	6	4
76	R:R:R226	R:R:R228	3.2	No	No	0	9	7
77	R:R:F227	R:R:R232	4.28	No	No	0	8	9
78	R:R:P230	R:R:R228	10.09	Yes	No	0	9	7
79	R:R:E231	R:R:R228	3.49	No	No	0	9	7
80	R:R:P230	R:R:Y229	4.17	Yes	Yes	0	9	9
81	R:R:T306	R:R:Y229	7.49	No	Yes	0	8	9
82	R:R:I320	R:R:Y229	7.25	Yes	Yes	0	8	9
83	R:R:F327	R:R:Y229	4.13	No	Yes	0	8	9
84	R:R:A310	R:R:P230	3.74	No	Yes	0	7	9
85	R:R:C317	R:R:P230	3.77	No	Yes	0	7	9
86	R:R:E231	R:R:I234	8.2	No	Yes	4	9	9
87	R:R:E231	R:R:W493	15.27	No	Yes	4	9	9
88	R:R:R232	R:R:Y236	4.12	No	Yes	0	9	8
89	R:R:E321	R:R:R232	4.65	No	No	0	6	9
90	R:R:P233	R:R:W299	5.4	Yes	Yes	2	7	9
91	R:R:I302	R:R:P233	6.77	Yes	Yes	2	7	7
92	R:R:L303	R:R:P233	3.28	No	Yes	0	9	7
93	R:R:P233	R:R:T306	5.25	Yes	No	0	7	8
94	R:R:I234	R:R:L303	4.28	Yes	No	0	9	9
95	R:R:F420	R:R:I234	5.02	No	Yes	4	8	9
96	R:R:A490	R:R:I234	3.25	No	Yes	0	8	9
97	R:R:I234	R:R:W493	7.05	Yes	Yes	4	9	9
98	R:R:I235	R:R:Y236	3.63	Yes	Yes	0	8	8
99	R:R:I235	R:R:S238	4.64	Yes	No	0	8	8
100	R:R:I235	R:R:V239	3.07	Yes	No	0	8	5
101	R:R:W299	R:R:Y236	15.43	Yes	Yes	2	9	8
102	R:R:H328	R:R:Y236	8.71	No	Yes	2	9	8
103	R:R:Y237	R:R:Y241	8.94	Yes	Yes	0	8	8
104	R:R:W300	R:R:Y237	3.86	Yes	Yes	3	9	8
105	R:R:Y237	R:R:Y424	7.94	Yes	Yes	3	8	8
106	R:R:S489	R:R:Y237	6.36	No	Yes	0	7	8
107	R:R:G296	R:R:Y241	7.24	No	Yes	0	8	8
108	R:R:V486	R:R:Y241	5.05	Yes	Yes	0	8	8
109	R:R:G487	R:R:Y241	5.79	No	Yes	0	9	8
110	R:R:F292	R:R:I243	6.28	Yes	No	0	9	5
111	R:R:T293	R:R:V244	3.17	No	No	0	6	7
112	R:R:L484	R:R:S245	6.01	Yes	No	1	8	8
113	R:R:I250	R:R:M247	5.83	No	No	0	4	6
114	R:R:S354	R:R:Y248	6.36	Yes	Yes	1	8	7
115	R:R:L484	R:R:Y248	4.69	Yes	Yes	1	8	7
116	R:R:F249	R:R:L253	9.74	No	No	0	5	3
117	R:R:L254	R:R:T258	2.95	Yes	No	0	4	7
118	R:R:S257	R:R:T258	3.2	No	No	0	3	7
119	R:R:K280	R:R:T258	6.01	No	No	0	7	7
120	R:R:N261	R:R:T272	2.92	No	No	0	5	6
121	R:R:N261	R:R:V274	2.96	No	No	0	5	7
122	R:R:D271	R:R:K262	15.21	No	No	0	4	3
123	R:R:C282	R:R:V274	5.12	Yes	No	0	9	7
124	R:R:G276	R:R:N346	5.09	No	No	0	7	6
125	R:R:N346	R:R:S277	8.94	No	No	0	6	7
126	R:R:N346	R:R:Q278	5.28	No	No	0	6	6
127	R:R:C282	R:R:N279	6.3	Yes	No	0	9	7
128	R:R:N279	R:R:T283	5.85	No	No	0	7	8
129	R:R:C282	R:R:V348	3.42	Yes	No	0	9	8
130	R:R:C282	R:R:C357	7.28	Yes	No	0	9	9
131	R:R:M287	R:R:T283	4.52	No	No	0	8	8
132	R:R:L288	R:R:V284	2.98	No	No	0	6	5
133	R:R:F286	R:R:L342	8.53	No	Yes	7	9	7
134	R:R:F286	R:R:V348	10.49	No	No	0	9	8
135	R:R:F286	R:R:V359	5.24	No	No	7	9	8
136	R:R:M287	R:R:T339	3.01	No	Yes	0	8	8
137	R:R:F358	R:R:L289	4.87	No	No	0	8	6
138	R:R:M294	R:R:Y290	11.97	No	Yes	0	7	9
139	R:R:L338	R:R:Y290	4.69	No	Yes	0	7	9
140	R:R:L342	R:R:Y290	4.69	Yes	Yes	0	7	9
141	R:R:F358	R:R:Y290	7.22	No	Yes	0	8	9
142	R:R:V371	R:R:Y290	7.57	No	Yes	0	7	9
143	R:R:F291	R:R:F292	5.36	Yes	Yes	2	9	9
144	R:R:F291	R:R:W332	6.01	Yes	Yes	2	9	9
145	R:R:F291	R:R:P335	5.78	Yes	No	0	9	9
146	R:R:F291	R:R:G336	3.01	Yes	No	2	9	8
147	R:R:F291	R:R:T339	5.19	Yes	Yes	2	9	8
148	R:R:F292	R:R:W332	3.01	Yes	Yes	2	9	9
149	R:R:M294	R:R:T297	3.01	No	No	0	7	6
150	R:R:A295	R:R:W332	3.89	No	Yes	0	9	9
151	R:R:L375	R:R:T297	4.42	No	No	0	6	6
152	R:R:I302	R:R:W299	7.05	Yes	Yes	2	7	9
153	R:R:H328	R:R:W299	11.64	No	Yes	2	9	9
154	R:R:A331	R:R:W299	9.08	No	Yes	2	9	9
155	R:R:W299	R:R:W332	7.5	Yes	Yes	2	9	9
156	R:R:T304	R:R:W300	7.28	No	Yes	3	7	9
157	R:R:G382	R:R:W300	4.22	No	Yes	3	8	9
158	R:R:W300	R:R:Y424	27.01	Yes	Yes	3	9	8
159	R:R:T304	R:R:V301	3.17	No	No	0	7	8
160	R:R:C378	R:R:V301	3.42	No	No	0	5	8
161	R:R:I302	R:R:I305	2.94	Yes	No	2	7	6
162	R:R:F327	R:R:I302	3.77	No	Yes	2	8	7
163	R:R:A331	R:R:I302	3.25	No	Yes	2	9	7
164	R:R:G382	R:R:T304	5.46	No	No	3	8	7
165	R:R:F327	R:R:I305	7.54	No	No	2	8	6
166	R:R:A311	R:R:W307	3.89	No	Yes	0	8	9
167	R:R:F413	R:R:W307	5.01	No	Yes	0	8	9
168	R:R:I417	R:R:W307	9.4	No	Yes	0	8	9
169	R:R:F308	R:R:G312	3.01	No	No	0	6	6
170	R:R:F308	R:R:L385	4.87	No	No	0	6	8
171	R:R:L309	R:R:W315	3.42	No	No	0	8	8
172	R:R:G312	R:R:S392	3.71	No	No	0	6	8
173	R:R:R313	R:R:W315	18.99	No	No	0	6	8
174	R:R:I320	R:R:W315	8.22	Yes	No	0	8	8
175	R:R:A319	R:R:S316	3.42	No	No	0	8	8
176	R:R:I320	R:R:S316	3.1	Yes	No	0	8	8
177	R:R:I320	R:R:K323	4.36	Yes	No	0	8	7
178	R:R:K323	R:R:Q322	6.78	No	No	0	7	6
179	R:R:H328	R:R:W332	6.35	No	Yes	2	9	9
180	R:R:T334	R:R:V330	3.17	No	No	0	5	5
181	R:R:P335	R:R:T334	3.5	No	No	0	9	5
182	R:R:G336	R:R:T339	3.64	No	Yes	2	8	8
183	R:R:M341	R:R:M345	4.33	No	No	0	5	5
184	R:R:L342	R:R:V359	4.47	Yes	No	7	7	8
185	R:R:F370	R:R:L342	6.09	No	Yes	0	8	7
186	R:R:L343	R:R:V348	4.47	No	No	0	8	8
187	R:R:D363	R:R:E349	9.09	No	No	0	7	8
188	R:R:C357	R:R:G350	3.92	No	No	0	9	8
189	R:R:D351	R:R:I353	5.6	Yes	Yes	1	9	7
190	R:R:D351	R:R:S354	4.42	Yes	Yes	1	9	8
191	R:R:D351	R:R:V356	5.84	Yes	No	1	9	8
192	R:R:D351	R:R:L361	4.07	Yes	No	0	9	7
193	R:R:D351	R:R:Y480	4.6	Yes	No	1	9	7
194	R:R:N352	R:R:Y362	5.81	No	No	0	7	5
195	R:R:I353	R:R:Y480	13.3	Yes	No	1	7	7
196	R:R:G355	R:R:S354	3.71	No	Yes	1	9	8
197	R:R:S354	R:R:V356	3.23	Yes	No	1	8	8
198	R:R:G355	R:R:V356	3.68	No	No	1	9	8
199	R:R:G360	R:R:S367	3.71	No	No	0	9	8
200	R:R:L361	R:R:Y362	4.69	No	No	0	7	5
201	R:R:A366	R:R:D363	4.63	No	No	0	5	7
202	R:R:L364	R:R:Q439	3.99	No	No	0	3	6
203	R:R:I443	R:R:L364	4.28	No	No	0	2	3
204	R:R:S367	R:R:V371	6.46	No	No	0	8	7
205	R:R:R368	R:R:Y369	10.29	No	No	0	6	3
206	R:R:Q439	R:R:R368	11.68	No	No	0	6	6
207	R:R:V371	R:R:Y435	3.79	No	No	0	7	6
208	R:R:L375	R:R:L428	6.92	No	Yes	0	6	8
209	R:R:C376	R:R:L432	3.17	No	No	0	3	6
210	R:R:L428	R:R:V379	4.47	Yes	No	0	8	8
211	R:R:L383	R:R:L425	5.54	No	No	0	5	6
212	R:R:L385	R:R:S384	4.5	No	No	0	8	4
213	R:R:L386	R:R:S421	6.01	No	No	0	8	8
214	R:R:I391	R:R:L387	7.14	No	No	0	5	5
215	R:R:I390	R:R:M414	2.92	No	No	0	7	8
216	R:R:I390	R:R:I417	4.42	No	No	0	7	8
217	R:R:H395	R:R:I391	5.3	No	No	0	7	5
218	R:R:L393	R:R:M414	8.48	No	No	0	8	8
219	R:R:L410	R:R:R397	8.5	No	No	0	8	8
220	R:R:K411	R:R:R397	16.09	No	No	0	8	8
221	R:R:N406	R:R:Q401	6.6	No	No	0	7	7
222	R:R:D403	R:R:H402	15.13	No	No	0	7	5
223	R:R:D403	R:R:R405	8.34	No	No	0	7	5
224	R:R:Q407	R:R:R405	7.01	No	No	0	7	5
225	R:R:E408	R:R:N406	3.94	No	No	0	5	7
226	R:R:L410	R:R:Q407	5.32	No	No	0	8	7
227	R:R:R416	R:R:W493	16.99	No	Yes	0	9	9
228	R:R:G418	R:R:S421	3.71	No	No	0	8	8
229	R:R:F492	R:R:V419	3.93	No	No	0	7	6
230	R:R:F420	R:R:S489	6.61	No	No	0	8	7
231	R:R:F420	R:R:W493	13.03	No	Yes	4	8	9
232	R:R:G422	R:R:S421	3.71	No	No	0	5	8
233	R:R:L423	R:R:S489	3	No	No	0	8	7
234	R:R:L428	R:R:Y424	3.52	Yes	Yes	3	8	8
235	R:R:V486	R:R:Y424	6.31	Yes	Yes	3	8	8
236	R:R:P427	R:R:V426	3.53	No	No	0	8	6
237	R:R:M482	R:R:P427	3.35	No	No	0	8	8
238	R:R:L428	R:R:V486	4.47	Yes	Yes	3	8	8
239	R:R:M482	R:R:T430	3.01	No	No	0	8	4
240	R:R:L431	R:R:T483	7.37	No	No	0	7	6
241	R:R:C434	R:R:K479	8.08	No	No	0	7	8
242	R:R:K479	R:R:Y435	4.78	No	No	0	8	6
243	R:R:N441	R:R:Y437	12.79	No	No	0	6	8
244	R:R:E472	R:R:Y437	10.1	No	No	8	6	8
245	R:R:L475	R:R:Y437	7.03	No	No	8	6	8
246	R:R:E438	R:R:W445	7.63	No	Yes	0	9	9
247	R:R:E438	R:R:L475	3.98	No	No	0	9	6
248	R:R:E438	R:R:F476	12.83	No	No	0	9	7
249	R:R:N441	R:R:V440	4.43	No	No	0	6	3
250	R:R:N441	R:R:W445	16.95	No	Yes	0	6	9
251	R:R:E446	R:R:I443	4.1	No	No	0	5	2
252	R:R:I447	R:R:T444	3.04	No	No	0	2	1
253	R:R:P471	R:R:W445	17.57	Yes	Yes	0	8	9
254	R:R:I447	R:R:P462	3.39	No	Yes	0	2	4
255	R:R:K468	R:R:T448	3	No	No	0	1	5
256	R:R:H453	R:R:W449	7.41	No	Yes	0	5	6
257	R:R:W449	R:R:Y457	9.65	Yes	No	0	6	4
258	R:R:I459	R:R:V450	3.07	Yes	No	0	6	3
259	R:R:P462	R:R:V450	3.53	Yes	No	0	4	3
260	R:R:P462	R:R:S451	3.56	Yes	No	0	4	3
261	R:R:A465	R:R:S451	3.42	No	No	0	2	3
262	R:R:K468	R:R:S451	3.06	No	No	0	1	3
263	R:R:D452	R:R:K468	6.91	No	No	0	4	1
264	R:R:C454	R:R:C461	7.28	No	No	0	9	9
265	R:R:Q456	R:R:Y457	3.38	No	No	0	1	4
266	R:R:I459	R:R:Y457	6.04	Yes	No	0	6	4
267	R:R:Q464	R:R:Y463	7.89	No	No	0	2	1
268	R:R:F476	R:R:P471	5.78	No	Yes	0	7	8
269	R:R:E472	R:R:L475	5.3	No	No	8	6	6
270	R:R:K479	R:R:T483	6.01	No	No	0	8	6
271	R:R:I485	R:R:M482	8.75	No	No	0	6	8
272	R:R:I485	R:R:I488	2.94	No	No	0	6	8
273	R:R:P471	R:R:R470	2.88	Yes	No	0	8	5
274	R:R:E194	R:R:S192	2.87	Yes	No	0	7	3
275	R:R:L285	R:R:M247	2.83	No	No	0	7	6
276	R:R:L289	R:R:M247	2.83	No	No	0	6	6
277	R:R:G389	R:R:W307	2.81	No	Yes	0	9	9
278	R:R:C240	R:R:F292	2.79	No	Yes	0	9	9
279	R:R:A198	R:R:F190	2.77	No	Yes	0	7	7
280	R:R:A388	R:R:F308	2.77	No	No	0	6	6
281	R:R:D365	R:R:K347	2.77	No	No	0	3	6
282	R:R:L375	R:R:L432	2.77	No	No	0	6	6
283	R:R:H402	R:R:V399	2.77	No	No	0	5	5
284	R:R:I400	R:R:Q407	2.74	No	No	0	7	7
285	R:R:A324	R:R:Y229	2.67	No	Yes	0	7	9
286	R:R:F215	R:R:V494	2.62	No	No	0	8	7
287	R:R:R225	R:R:V224	2.62	No	No	0	4	6
288	R:R:A469	R:R:W445	2.59	No	Yes	0	3	9
289	R:R:H164	R:R:L269	2.57	No	No	0	6	2
290	R:R:V244	R:R:Y241	2.52	No	Yes	0	7	8
291	R:R:F249	R:R:I207	2.51	No	No	0	5	4
292	R:R:F190	R:R:M477	2.49	Yes	No	0	7	7
293	R:R:F337	R:R:M341	2.49	No	No	0	4	5
294	R:R:F370	R:R:M341	2.49	No	No	0	8	5
295	R:R:F370	R:R:K347	2.48	No	No	0	8	6
296	R:R:F217	R:R:L214	2.44	No	No	0	6	5
297	R:R:F292	R:R:L288	2.44	Yes	No	0	9	6
298	R:R:F492	R:R:L423	2.44	No	No	0	7	8
299	R:R:L373	R:R:R368	2.43	No	No	0	4	6
300	R:R:I417	R:R:W493	2.35	No	Yes	0	8	9
301	R:R:K323	R:R:W326	2.32	No	No	0	7	7
302	R:R:L386	R:R:W300	2.28	No	Yes	0	8	9
303	R:R:F197	R:R:F201	2.14	No	No	0	6	8
304	R:R:G169	R:R:G170	2.11	No	No	0	3	4
305	R:R:C461	R:R:P462	1.88	No	Yes	0	9	4
306	R:R:G389	R:R:S392	1.86	No	No	0	9	8
307	R:R:G382	R:R:V381	1.84	No	No	0	8	5
308	R:R:P335	R:R:V298	1.77	No	No	0	9	6
309	R:R:P427	R:R:V486	1.77	No	Yes	0	8	8
310	R:R:G177	R:R:I178	1.76	No	No	0	4	5
311	R:R:G177	R:R:K174	1.74	No	No	0	4	3
312	R:R:G251	R:R:L254	1.71	No	Yes	0	9	4
313	R:R:G255	R:R:L254	1.71	No	Yes	0	6	4
314	R:R:G422	R:R:L425	1.71	No	No	0	5	6
315	R:R:I459	R:R:P460	1.69	Yes	No	0	6	5
316	R:R:M294	R:R:P374	1.68	No	No	0	7	9
317	R:R:D403	R:R:G404	1.68	No	No	0	7	5
318	R:R:C434	R:R:I478	1.64	No	No	0	7	6
319	R:R:A281	R:R:K280	1.61	No	No	0	5	7
320	R:R:A344	R:R:M345	1.61	No	No	0	7	5
321	R:R:T339	R:R:V340	1.59	Yes	No	0	8	7
322	R:R:C378	R:R:L377	1.59	No	No	0	5	4
323	R:R:I207	R:R:T204	1.52	No	No	0	4	4
324	R:R:K314	R:R:V396	1.52	No	No	0	8	8
325	R:R:L372	R:R:V436	1.49	No	No	0	7	4
326	R:R:L393	R:R:V396	1.49	No	No	0	8	8
327	R:R:D193	R:R:S192	1.47	No	No	0	3	3
328	R:R:E318	R:R:S316	1.44	No	No	0	9	8
329	R:R:I222	R:R:L218	1.43	No	No	0	8	5
330	R:R:M414	R:R:N394	1.4	No	No	0	8	6
331	R:R:D179	R:R:K174	1.38	No	No	0	4	3
332	R:R:L254	R:R:L285	1.38	Yes	No	0	4	7
333	R:R:I400	R:R:Q401	1.37	No	No	0	7	7
334	R:R:E194	R:R:K191	1.35	Yes	No	0	7	5
335	R:R:L372	R:R:Q439	1.33	No	No	0	7	6
336	R:R:L364	R:R:R442	1.21	No	No	0	3	6
337	R:R:H164	R:R:R163	1.13	No	No	0	6	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F190	4.76	6	1	7
2	R:R:E194	2.925	4	1	7
3	R:R:I202	4.4475	4	1	7
4	R:R:T216	4.796	5	6	8
5	R:R:Y229	5.142	5	0	9
6	R:R:P230	5.4425	4	0	9
7	R:R:P233	5.175	4	2	7
8	R:R:I234	5.56	5	4	9
9	R:R:I235	5.975	4	0	8
10	R:R:Y236	7.9725	4	2	8
11	R:R:Y237	6.775	4	3	8
12	R:R:Y241	5.908	5	0	8
13	R:R:Y248	5.2275	4	1	7
14	R:R:L254	1.9375	4	0	4
15	R:R:L275	3.485	4	0	8
16	R:R:C282	5.53	4	0	9
17	R:R:Y290	7.228	5	0	9
18	R:R:F291	5.07	5	2	9
19	R:R:F292	3.976	5	2	9
20	R:R:W299	9.35	6	2	9
21	R:R:W300	8.93	5	3	9
22	R:R:I302	4.756	5	2	7
23	R:R:W307	5.2775	4	0	9
24	R:R:I320	5.7325	4	0	8
25	R:R:W332	5.352	5	2	9
26	R:R:T339	3.3575	4	2	8
27	R:R:L342	5.945	4	7	7
28	R:R:D351	4.906	5	1	9
29	R:R:I353	7.7925	4	1	7
30	R:R:S354	4.164	5	1	8
31	R:R:Y424	11.195	4	3	8
32	R:R:L428	4.845	4	3	8
33	R:R:W445	11.185	4	0	9
34	R:R:W449	7.99	4	0	6
35	R:R:I459	4.3925	4	0	6
36	R:R:P462	3.09	4	0	4
37	R:R:P471	9.34	4	0	8
38	R:R:L484	5.7775	4	1	8
39	R:R:V486	4.4	4	3	8
40	R:R:W493	10.938	5	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F159	R:R:L176	10.5666	6.09	No	No	0	4	5
2	R:R:C161	R:R:P162	13.6116	3.77	No	No	0	9	6
3	R:R:I459	R:R:P162	12.3343	6.77	Yes	No	0	6	6
4	R:R:C161	R:R:C181	14.9313	7.28	No	No	0	9	9
5	R:R:C181	R:R:F175	18.7451	4.19	No	No	0	9	6
6	R:R:F175	R:R:Y173	37.9623	7.22	No	No	0	6	6
7	R:R:L275	R:R:Y173	41.1223	3.52	Yes	No	0	8	6
8	R:R:E446	R:R:L176	11.3052	11.93	No	No	0	5	5
9	R:R:A182	R:R:L275	99.3765	3.15	No	Yes	0	7	8
10	R:R:A182	R:R:T272	99.546	3.36	No	No	0	7	6
11	R:R:L275	R:R:P183	68.9206	3.28	Yes	No	0	8	6
12	R:R:P183	R:R:Y362	67.8582	8.34	No	No	0	6	5
13	R:R:I459	R:R:Y457	13.2484	6.04	Yes	No	0	6	4
14	R:R:W449	R:R:Y457	12.1133	9.65	Yes	No	0	6	4
15	R:R:F476	R:R:P471	15.8726	5.78	No	Yes	0	7	8
16	R:R:F190	R:R:F476	29.2027	7.5	Yes	No	0	7	7
17	R:R:F190	R:R:I353	47.972	3.77	Yes	Yes	1	7	7
18	R:R:I353	R:R:N187	22.1624	8.5	Yes	No	0	7	6
19	R:R:N352	R:R:Y362	23.7605	5.81	No	No	0	7	5
20	R:R:D351	R:R:I353	24.5778	5.6	Yes	Yes	1	9	7
21	R:R:D351	R:R:S354	17.383	4.42	Yes	Yes	1	9	8
22	R:R:S354	R:R:Y248	11.7531	6.36	Yes	Yes	1	8	7
23	R:R:P427	R:R:V486	11.4505	1.77	No	Yes	0	8	8
24	R:R:L375	R:R:L428	31.2912	6.92	No	Yes	0	6	8
25	R:R:L375	R:R:T297	31.8179	4.42	No	No	0	6	6
26	R:R:M294	R:R:T297	32.0298	3.01	No	No	0	7	6
27	R:R:M294	R:R:Y290	32.4959	11.97	No	Yes	0	7	9
28	R:R:L342	R:R:Y290	39.3184	4.69	Yes	Yes	0	7	9
29	R:R:F286	R:R:L342	42.3906	8.53	No	Yes	7	9	7
30	R:R:F286	R:R:V348	43.6316	10.49	No	No	0	9	8
31	R:R:C282	R:R:V348	44.8181	3.42	Yes	No	0	9	8
32	R:R:C282	R:R:V274	100	5.12	Yes	No	0	9	7
33	R:R:N261	R:R:V274	99.8547	2.96	No	No	0	5	7
34	R:R:N261	R:R:T272	99.7034	2.92	No	No	0	5	6
35	R:R:C282	R:R:N279	70.2282	6.3	Yes	No	0	9	7
36	R:R:N279	R:R:T283	69.9134	5.85	No	No	0	7	8
37	R:R:M287	R:R:T283	69.6531	4.52	No	No	0	8	8
38	R:R:M287	R:R:T339	69.5018	3.01	No	Yes	0	8	8
39	R:R:F291	R:R:T339	68.627	5.19	Yes	Yes	2	9	8
40	R:R:F291	R:R:W332	65.2794	6.01	Yes	Yes	2	9	9
41	R:R:W299	R:R:W332	53.6382	7.5	Yes	Yes	2	9	9
42	R:R:W299	R:R:Y236	16.9502	15.43	Yes	Yes	2	9	8
43	R:R:I235	R:R:Y236	15.5397	3.63	Yes	Yes	0	8	8
44	R:R:H328	R:R:W332	13.7085	6.35	No	Yes	2	9	9
45	R:R:H328	R:R:Y236	13.1152	8.71	No	Yes	2	9	8
46	R:R:I234	R:R:L303	23.7938	4.28	Yes	No	0	9	9
47	R:R:L303	R:R:P233	24.1147	3.28	No	Yes	0	9	7
48	R:R:P233	R:R:W299	31.1823	5.4	Yes	Yes	2	7	9
49	R:R:R232	R:R:Y236	13.5571	4.12	No	Yes	0	9	8
50	R:R:E231	R:R:R228	10.6453	3.49	No	No	0	9	7
51	R:R:P233	R:R:T306	14.6347	5.25	Yes	No	0	7	8
52	R:R:T306	R:R:Y229	13.7599	7.49	No	Yes	0	8	9
53	R:R:P230	R:R:Y229	12.7368	4.17	Yes	Yes	0	9	9
54	R:R:P230	R:R:R228	10.7119	10.09	Yes	No	0	9	7
55	R:R:I302	R:R:W299	12.7944	7.05	Yes	Yes	2	7	9
56	R:R:F327	R:R:I302	11.7683	3.77	No	Yes	2	8	7
57	R:R:F327	R:R:Y229	10.8996	4.13	No	Yes	0	8	9
58	R:R:I320	R:R:Y229	20.9426	7.25	Yes	Yes	0	8	9
59	R:R:I234	R:R:W493	12.2677	7.05	Yes	Yes	4	9	9
60	R:R:F420	R:R:I234	16.5325	5.02	No	Yes	4	8	9
61	R:R:L428	R:R:Y424	22.0988	3.52	Yes	Yes	3	8	8
62	R:R:Y237	R:R:Y424	16.9926	7.94	Yes	Yes	3	8	8
63	R:R:S489	R:R:Y237	26.633	6.36	No	Yes	0	7	8
64	R:R:F358	R:R:Y290	13.3271	7.22	No	Yes	0	8	9
65	R:R:F358	R:R:L289	12.2495	4.87	No	No	0	8	6
66	R:R:L289	R:R:M247	11.1659	2.83	No	No	0	6	6
67	R:R:V371	R:R:Y290	10.0763	7.57	No	Yes	0	7	9
68	R:R:I417	R:R:W493	16.4659	2.35	No	Yes	0	8	9
69	R:R:L361	R:R:Y362	43.7799	4.69	No	No	0	7	5
70	R:R:E438	R:R:F476	12.8488	12.83	No	No	0	9	7
71	R:R:P462	R:R:V450	10.6816	3.53	Yes	No	0	4	3
72	R:R:E446	R:R:F175	19.1022	4.66	No	No	0	5	6
73	R:R:N187	R:R:N352	23.1794	4.09	No	No	0	6	7
74	R:R:D351	R:R:L361	43.1866	4.07	Yes	No	0	9	7
75	R:R:F420	R:R:S489	25.1196	6.61	No	No	0	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8JHB_nogp

PDB Summary
PDB	8JHB_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.92
Number of Linked Nodes	310
Number of Links	337
Number of Hubs	40
Number of Links mediated by Hubs	146
Number of Communities	8
Number of Nodes involved in Communities	50
Number of Links involved in Communities	65

Path Summary
Number Of Nodes in MetaPath	76
Number Of Links MetaPath	75
Number of Shortest Paths	61778
Length Of Smallest Path	3
Average Path Length	17.7607
Length of Longest Path	38
Minimum Path Strength	1.41
Average Path Strength	5.4483
Maximum Path Strength	17.26
Minimum Path Correlation	0.7
Average Path Correlation	0.938361
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	48.2893
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.6129
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • mu-type opioid receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • ionotropic glutamate receptor binding • glutamate receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • peptide hormone receptor binding • corticotropin-releasing hormone receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • cation binding • metal ion binding • insulin-like growth factor receptor binding • developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • animal organ development • bone development • system development • regulation of body fluid levels • wound healing • response to stimulus • homotypic cell-cell adhesion • cell activation • hemostasis
Gene Ontology	Biological Process	• developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • animal organ development • bone development • system development • regulation of body fluid levels • wound healing • response to stimulus • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • cellular process • regulation of biological quality • response to wounding • platelet activation • developmental growth • growth • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • cellular response to catecholamine stimulus • serotonin receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-activating serotonin receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to hormone • response to endogenous stimulus • response to alcohol • response to prostaglandin E • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • apical part of cell • plasma membrane region • apical plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • Wnt receptor activity • G protein-coupled receptor activity • ubiquitin protein ligase binding • ubiquitin-like protein ligase binding • Wnt-protein binding • limb development • appendage development • embryonic morphogenesis • embryonic limb morphogenesis • embryo development • embryonic appendage morphogenesis • embryonic nail plate morphogenesis • anatomical structure morphogenesis • nail development • appendage morphogenesis • embryonic digit morphogenesis • limb morphogenesis • negative regulation of DNA-binding transcription factor activity • RNA metabolic process • regulation of primary metabolic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • DNA-templated transcription • regulation of RNA metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of biosynthetic process • negative regulation of molecular function • primary metabolic process • regulation of macromolecule metabolic process • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • regulation of molecular function • regulation of gene expression • biosynthetic process • regulation of DNA-binding transcription factor activity • metabolic process • regulation of macromolecule biosynthetic process • regulation of DNA-templated transcription • macromolecule metabolic process • regulation of metabolic process • cell surface receptor signaling pathway • canonical Wnt signaling pathway • Wnt signaling pathway • head development • brain development • nervous system development • central nervous system development • cell proliferation in midbrain • midbrain development • neural precursor cell proliferation • ear morphogenesis • embryonic organ morphogenesis • ear development • sensory organ morphogenesis • inner ear development • inner ear morphogenesis • animal organ morphogenesis • embryonic organ development • non-canonical Wnt signaling pathway • negative regulation of signaling • regulation of canonical Wnt signaling pathway • negative regulation of biological process • regulation of signal transduction • negative regulation of cell communication • negative regulation of Wnt signaling pathway • negative regulation of cellular process • regulation of signaling • regulation of Wnt signaling pathway • negative regulation of response to stimulus • negative regulation of signal transduction • negative regulation of canonical Wnt signaling pathway • regulation of response to stimulus • regulation of cell communication • epithelium development • epidermis development • molting cycle process • hair cycle • tissue development • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • embryonic epithelial tube formation • chordate embryonic development • tube formation • epithelial tube formation • tube morphogenesis • primary neural tube formation • embryo development ending in birth or egg hatching • epithelial tube morphogenesis • morphogenesis of embryonic epithelium • neural tube development • tube development • morphogenesis of an epithelium • tissue morphogenesis • neural tube closure • neural tube formation • anatomical structure formation involved in morphogenesis • tube closure • regulation of body fluid levels • wound healing • cell activation • hemostasis • blood coagulation • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • Wnt signaling pathway, planar cell polarity pathway • establishment of planar polarity • establishment of body hair or bristle planar orientation • establishment of tissue polarity • morphogenesis of a polarized epithelium • establishment of body hair planar orientation • brain morphogenesis • midbrain morphogenesis • cell surface • apicolateral plasma membrane • organelle subcompartment • endomembrane system • endoplasmic reticulum subcompartment • nuclear outer membrane-endoplasmic reticulum membrane network • endoplasmic reticulum • endoplasmic reticulum membrane • intracellular vesicle • cytoplasmic vesicle membrane • vesicle membrane • cytoplasmic vesicle • intracellular membraneless organelle • ciliary basal body • microtubule organizing center • cytoskeleton • membraneless organelle • microtubule cytoskeleton
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O60353
Sequence	>8JHB_nogp_Chain_R I G F W C P R H L K T S G G Q G Y K F L G I D Q C A P P C P N M Y F K S D E L E F A K S F I G T V S I F C L C A T L F T F L T F L I D V R R F R Y P E R P I I Y Y S V C Y S I V S L M Y F I G F L L G D S T A C N K E L G D T V V L G S Q N K A C T V L F M L L Y F F T M A G T V W W V I L T I T W F L A A G R K W S C E A I E Q K A V W F H A V A W G T P G F L T V M L L A M N K V E G D N I S G V C F V G L Y D L D A S R Y F V L L P L C L C V F V G L S L L L A G I I S L N H V R Q V I Q H D G R N Q E K L K K F M I R I G V F S G L Y L V P L V T L L G C Y V Y E Q V N R I T W E I T W V S D H C R Q Y H I P C P Y Q A K A K A R P E L A L F M I K Y L M T L I V G I S A V F W V G Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8JH7	F	Protein	Frizzled	FZD₆	Homo sapiens	-	-	-	3.2	2024-01-17	10.1038/s41421-023-00627-y
	8JHB	F	Protein	Frizzled	FZD₆	Homo sapiens	-	-	chim(NtGsXLas-Gs)/β1/γ2	3.3	2024-01-17	10.1038/s41421-023-00627-y
	8JHB (No Gprot)	F	Protein	Frizzled	FZD₆	Homo sapiens	-	-		3.3	2024-01-17	10.1038/s41421-023-00627-y

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