psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:N6	A:A:T9	5.85	No	No	0	4	6
2	A:A:K12	A:A:R13	4.95	No	No	0	4	9
3	A:A:K16	A:A:R13	6.19	No	No	0	5	9
4	A:A:K16	A:A:R17	8.66	No	No	0	5	8
5	A:A:K20	A:A:R17	3.71	No	No	0	5	8
6	A:A:R22	B:B:H91	4.51	No	Yes	0	6	5
7	A:A:S23	B:B:N88	8.94	No	No	0	8	7
8	A:A:I26	B:B:K89	5.82	No	Yes	0	8	9
9	A:A:I26	B:B:A92	3.25	No	No	0	8	6
10	A:A:D32	A:A:Q29	3.92	No	No	0	2	9
11	A:A:K34	B:B:L55	4.23	Yes	Yes	0	9	6
12	A:A:K34	R:R:E322	10.8	Yes	No	0	9	9
13	A:A:R42	A:A:Y37	9.26	Yes	Yes	1	9	9
14	A:A:D240	A:A:Y37	3.45	No	Yes	1	6	9
15	A:A:Y37	B:B:L55	4.69	Yes	Yes	0	9	6
16	A:A:M38	R:R:E322	4.06	No	No	0	7	9
17	A:A:N218	A:A:T40	5.85	No	No	0	4	7
18	A:A:H220	A:A:T40	8.21	Yes	No	0	7	7
19	A:A:F219	A:A:H41	7.92	Yes	No	8	8	6
20	A:A:H41	A:A:T242	5.48	No	No	8	6	8
21	A:A:H41	A:A:I383	7.95	No	Yes	8	6	8
22	A:A:H220	A:A:R42	3.39	Yes	Yes	1	7	9
23	A:A:F222	A:A:R42	4.28	Yes	Yes	1	7	9
24	A:A:D240	A:A:R42	7.15	No	Yes	1	6	9
25	A:A:F219	A:A:L43	4.87	Yes	No	0	8	7
26	A:A:I245	A:A:L43	4.28	No	No	0	7	7
27	A:A:L44	A:A:L46	8.3	No	No	0	9	8
28	A:A:F238	A:A:L44	19.49	Yes	No	0	9	9
29	A:A:L45	A:A:M221	7.07	No	No	0	8	8
30	A:A:I245	A:A:L45	8.56	No	No	0	7	8
31	A:A:G47	A:A:S51	3.71	No	No	0	9	9
32	A:A:A48	A:A:S51	3.42	No	No	0	8	9
33	A:A:D49	A:A:N50	5.39	No	Yes	17	8	9
34	A:A:D49	A:A:R265	8.34	No	Yes	17	8	9
35	A:A:D249	A:A:N50	4.04	No	Yes	0	8	9
36	A:A:D252	A:A:N50	4.04	No	Yes	17	8	9
37	A:A:N50	A:A:R265	12.05	Yes	Yes	17	9	9
38	A:A:K53	A:A:S51	4.59	No	No	0	9	9
39	A:A:D223	A:A:K53	12.44	No	No	0	9	9
40	A:A:K53	A:A:V247	3.04	No	No	0	9	7
41	A:A:I56	A:A:V247	3.07	No	No	0	7	7
42	A:A:F290	A:A:I56	3.77	Yes	No	0	9	7
43	A:A:F212	A:A:V57	3.93	Yes	No	0	9	7
44	A:A:M60	A:A:Q59	6.8	No	No	0	9	9
45	A:A:F212	A:A:M60	3.73	Yes	No	0	9	9
46	A:A:R61	A:A:T210	11.64	No	No	0	8	7
47	A:A:I207	A:A:V224	4.61	No	No	0	9	9
48	A:A:D223	A:A:F208	3.58	No	No	0	9	5
49	A:A:E209	A:A:H220	6.15	No	Yes	1	9	7
50	A:A:E209	A:A:F222	12.83	No	Yes	1	9	7
51	A:A:M221	A:A:T210	4.52	No	No	0	8	7
52	A:A:H220	A:A:K211	6.55	Yes	No	0	7	4
53	A:A:F212	A:A:F219	13.93	Yes	Yes	0	9	8
54	A:A:F212	A:A:M221	4.98	Yes	No	0	9	8
55	A:A:N218	A:A:Q213	9.24	No	No	0	4	3
56	A:A:D215	A:A:V214	5.84	No	No	8	5	6
57	A:A:F376	A:A:V214	6.55	Yes	No	8	8	6
58	A:A:D215	A:A:R373	5.96	No	No	8	5	5
59	A:A:D215	A:A:F376	7.17	No	Yes	8	5	8
60	A:A:F219	A:A:V217	6.55	Yes	No	8	8	5
61	A:A:F376	A:A:V217	7.87	Yes	No	8	8	5
62	A:A:F219	A:A:F376	4.29	Yes	Yes	8	8	8
63	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
64	A:A:F222	A:A:H220	4.53	Yes	Yes	1	7	7
65	A:A:F222	B:B:W99	20.04	Yes	Yes	0	7	9
66	A:A:V224	A:A:W234	3.68	No	Yes	15	9	9
67	A:A:F238	A:A:V224	5.24	Yes	No	15	9	9
68	A:A:Q227	A:A:W234	6.57	Yes	Yes	0	9	9
69	A:A:Q227	B:B:L117	5.32	Yes	No	0	9	9
70	A:A:Q227	B:B:N119	10.56	Yes	No	0	9	9
71	A:A:Q227	B:B:Y145	4.51	Yes	Yes	0	9	8
72	A:A:E230	A:A:R228	12.79	Yes	No	1	9	9
73	A:A:R228	B:B:D186	5.96	No	Yes	1	9	9
74	A:A:E230	A:A:R232	11.63	Yes	No	0	9	8
75	A:A:E230	B:B:D186	5.2	Yes	Yes	1	9	9
76	A:A:R231	A:A:W234	9	No	Yes	15	9	9
77	A:A:I235	A:A:R231	5.01	No	No	15	9	9
78	A:A:L272	A:A:R231	8.5	No	No	0	8	9
79	A:A:R232	B:B:D228	10.72	No	No	0	8	9
80	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
81	A:A:K233	B:B:M188	8.64	Yes	No	1	9	8
82	A:A:K233	B:B:C204	4.85	Yes	Yes	1	9	7
83	A:A:K233	B:B:D228	6.91	Yes	No	1	9	9
84	A:A:K233	B:B:N230	4.2	Yes	No	0	9	9
85	A:A:I235	A:A:W234	3.52	No	Yes	15	9	9
86	A:A:F238	A:A:W234	4.01	Yes	Yes	15	9	9
87	A:A:I235	A:A:L282	4.28	No	No	0	9	9
88	A:A:Q236	A:A:W281	10.95	No	Yes	1	8	5
89	A:A:Q236	B:B:R314	4.67	No	Yes	1	8	8
90	A:A:C237	B:B:Y59	5.38	No	Yes	1	8	8
91	A:A:C237	B:B:M101	4.86	No	Yes	1	8	9
92	A:A:C237	B:B:L117	3.17	No	No	0	8	9
93	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
94	A:A:F238	B:B:W99	12.03	Yes	Yes	0	9	9
95	A:A:N239	B:B:W332	5.65	No	Yes	0	8	9
96	A:A:D240	B:B:K57	6.91	No	Yes	1	6	9
97	A:A:I285	A:A:V241	3.07	No	No	0	7	9
98	A:A:I383	A:A:T242	3.04	Yes	No	8	8	8
99	A:A:A243	A:A:I288	3.25	No	No	0	8	9
100	A:A:I244	A:A:V287	3.07	No	No	0	8	6
101	A:A:F246	A:A:V248	3.93	No	No	0	9	7
102	A:A:F246	A:A:L272	7.31	No	No	0	9	8
103	A:A:F246	A:A:F273	5.36	No	Yes	0	9	9
104	A:A:N292	A:A:V247	4.43	No	No	0	9	7
105	A:A:A269	A:A:V248	3.39	No	No	0	9	7
106	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
107	A:A:D249	A:A:S251	5.89	No	No	0	8	9
108	A:A:D249	A:A:K293	15.21	No	No	0	8	9
109	A:A:L291	A:A:S250	4.5	No	No	0	8	6
110	A:A:L296	A:A:S251	4.5	No	No	0	6	9
111	A:A:K300	A:A:S251	4.59	No	No	0	9	9
112	A:A:D252	A:A:N264	4.04	No	No	0	8	9
113	A:A:D252	A:A:R265	8.34	No	Yes	17	8	9
114	A:A:L297	A:A:Y253	3.52	No	Yes	0	8	8
115	A:A:K300	A:A:Y253	9.55	No	Yes	21	9	8
116	A:A:S306	A:A:Y253	5.09	No	Yes	21	7	8
117	A:A:I308	A:A:Y253	6.04	No	Yes	0	7	8
118	A:A:Y253	A:A:Y311	9.93	Yes	No	0	8	6
119	A:A:N264	A:A:Y311	8.14	No	No	0	9	6
120	A:A:E268	A:A:R265	11.63	No	Yes	0	9	9
121	A:A:F312	A:A:L266	6.09	No	No	0	8	8
122	A:A:I341	A:A:L266	5.71	No	No	0	8	8
123	A:A:L270	A:A:Q267	5.32	No	No	0	6	4
124	A:A:N271	A:A:Q267	6.6	No	No	0	5	4
125	A:A:E344	A:A:L270	5.3	Yes	No	0	5	6
126	A:A:F345	A:A:L270	9.74	Yes	No	0	8	6
127	A:A:I276	A:A:L272	4.28	No	No	0	8	8
128	A:A:F273	A:A:W277	6.01	Yes	Yes	4	9	6
129	A:A:F273	A:A:V287	5.24	Yes	No	4	9	6
130	A:A:F273	A:A:L289	7.31	Yes	No	4	9	9
131	A:A:F273	A:A:F345	4.29	Yes	Yes	4	9	8
132	A:A:F273	A:A:I348	5.02	Yes	No	0	9	4
133	A:A:K274	A:A:N278	4.2	No	No	0	5	8
134	A:A:V287	A:A:W277	4.9	No	Yes	4	6	6
135	A:A:S352	A:A:W277	4.94	No	Yes	0	5	6
136	A:A:H357	A:A:W277	28.56	No	Yes	0	7	6
137	A:A:N278	A:A:S352	5.96	No	No	0	8	5
138	A:A:L282	A:A:N279	9.61	No	No	0	9	8
139	A:A:R280	A:A:W281	20.99	No	Yes	0	5	5
140	A:A:W281	B:B:D290	8.93	Yes	Yes	1	5	6
141	A:A:W281	B:B:R314	18.99	Yes	Yes	1	5	8
142	A:A:I382	A:A:S286	9.29	No	No	0	6	8
143	A:A:D378	A:A:I288	7	No	No	0	7	9
144	A:A:F345	A:A:L289	10.96	Yes	No	4	8	9
145	A:A:C359	A:A:L289	4.76	No	No	4	5	9
146	A:A:F290	A:A:T364	6.49	Yes	No	18	9	9
147	A:A:F290	A:A:N371	6.04	Yes	No	18	9	9
148	A:A:F290	A:A:I375	3.77	Yes	No	0	9	9
149	A:A:F363	A:A:L291	3.65	Yes	No	0	5	8
150	A:A:K293	A:A:N292	5.6	No	No	0	9	9
151	A:A:K293	A:A:L296	5.64	No	No	0	9	6
152	A:A:K338	A:A:Q294	6.78	No	No	4	5	6
153	A:A:F363	A:A:Q294	10.54	Yes	No	4	5	6
154	A:A:C365	A:A:D295	4.67	No	No	0	8	9
155	A:A:E299	A:A:L302	6.63	No	No	0	6	2
156	A:A:K300	A:A:S306	3.06	No	No	21	9	7
157	A:A:V301	A:A:V334	3.21	No	Yes	0	7	4
158	A:A:E309	A:A:K307	14.85	No	No	0	4	6
159	A:A:D310	A:A:K307	5.53	No	No	0	3	6
160	A:A:F315	A:A:I308	15.07	Yes	No	0	6	7
161	A:A:E309	A:A:F315	4.66	No	Yes	0	4	6
162	A:A:F312	A:A:F340	7.5	No	Yes	12	8	7
163	A:A:E344	A:A:F312	8.16	Yes	No	12	5	8
164	A:A:E314	A:A:P313	6.29	No	No	0	6	6
165	A:A:E314	A:A:E344	5.07	No	Yes	0	6	5
166	A:A:F315	A:A:R336	14.97	Yes	No	0	6	5
167	A:A:F315	A:A:F340	12.86	Yes	Yes	0	6	7
168	A:A:P321	A:A:Y318	5.56	Yes	No	12	5	6
169	A:A:F340	A:A:Y318	11.35	Yes	No	12	7	6
170	A:A:D343	A:A:Y318	11.49	No	No	12	3	6
171	A:A:P321	A:A:T320	3.5	Yes	No	0	5	1
172	A:A:T320	A:A:T335	3.14	No	No	0	1	4
173	A:A:R336	A:A:T320	3.88	No	No	0	5	1
174	A:A:A324	A:A:P321	3.74	No	Yes	0	3	5
175	A:A:D343	A:A:P321	4.83	No	Yes	12	3	5
176	A:A:A324	A:A:Y339	9.34	No	Yes	0	3	3
177	A:A:E330	A:A:P326	3.14	Yes	No	0	3	1
178	A:A:E327	A:A:P328	11	No	No	0	4	1
179	A:A:E327	A:A:E330	6.34	No	Yes	22	4	3
180	A:A:E330	A:A:V334	5.7	Yes	Yes	0	3	4
181	A:A:E330	A:A:T335	5.64	Yes	No	0	3	4
182	A:A:D331	A:A:R333	9.53	No	No	0	4	5
183	A:A:D331	A:A:V334	8.76	No	Yes	0	4	4
184	A:A:K338	A:A:Y339	5.97	No	Yes	4	5	3
185	A:A:F363	A:A:K338	12.41	Yes	No	4	5	5
186	A:A:R342	A:A:Y339	8.23	Yes	Yes	4	4	3
187	A:A:F363	A:A:Y339	6.19	Yes	Yes	4	5	3
188	A:A:E344	A:A:F340	3.5	Yes	Yes	12	5	7
189	A:A:L346	A:A:R342	3.64	Yes	Yes	4	4	4
190	A:A:P361	A:A:R342	8.65	No	Yes	4	5	4
191	A:A:F363	A:A:R342	6.41	Yes	Yes	4	5	4
192	A:A:E344	A:A:R347	5.82	Yes	No	0	5	4
193	A:A:L346	A:A:S349	7.51	Yes	No	4	4	7
194	A:A:C359	A:A:L346	3.17	No	Yes	4	5	4
195	A:A:L346	A:A:P361	4.93	Yes	No	4	4	5
196	A:A:S349	A:A:T350	6.4	No	No	0	7	4
197	A:A:C359	A:A:S349	3.44	No	No	4	5	7
198	A:A:G353	A:A:S352	3.71	No	No	0	4	5
199	A:A:G353	A:A:H357	3.18	No	No	0	4	7
200	A:A:G355	A:A:Y358	5.79	No	No	0	2	4
201	A:A:R356	A:A:R389	11.73	Yes	No	23	2	4
202	A:A:R385	A:A:Y358	6.17	No	No	0	5	4
203	A:A:Y358	R:R:K408	5.97	No	No	0	4	7
204	A:A:D378	A:A:Y360	11.49	No	Yes	0	7	8
205	A:A:D381	A:A:Y360	9.2	No	Yes	24	8	8
206	A:A:I382	A:A:Y360	8.46	No	Yes	0	6	8
207	A:A:R385	A:A:Y360	9.26	No	Yes	24	5	8
208	A:A:H362	A:A:R374	10.16	No	No	0	9	4
209	A:A:D378	A:A:H362	13.87	No	No	0	7	9
210	A:A:D368	A:A:T364	4.34	No	No	18	9	9
211	A:A:N371	A:A:T364	8.77	No	No	18	9	9
212	A:A:C365	A:A:V367	3.42	No	No	0	8	9
213	A:A:D368	A:A:E370	12.99	No	No	0	9	4
214	A:A:D368	A:A:N371	13.46	No	No	18	9	9
215	A:A:E370	A:A:R374	15.12	No	No	0	4	4
216	A:A:F376	A:A:R373	8.55	Yes	No	8	8	5
217	A:A:N377	A:A:R373	7.23	No	No	0	4	5
218	A:A:F376	A:A:R380	12.83	Yes	No	0	8	7
219	A:A:N377	A:A:R380	8.44	No	No	0	4	7
220	A:A:D381	A:A:R385	15.48	No	No	24	8	5
221	A:A:Y391	R:R:R232	7.2	No	No	0	4	6
222	A:A:L393	R:R:L414	4.15	No	No	0	8	9
223	A:A:L393	R:R:F417	17.05	No	No	0	8	8
224	A:A:L394	R:R:K413	12.69	No	No	0	8	9
225	B:B:L4	G:G:Q11	9.32	No	Yes	0	4	3
226	B:B:D5	B:B:R8	5.96	No	No	0	1	3
227	B:B:D5	B:B:Q9	7.83	No	No	0	1	3
228	B:B:L7	B:B:Q6	6.65	Yes	No	0	8	1
229	B:B:E10	B:B:L7	6.63	No	Yes	25	8	8
230	B:B:L7	G:G:Q11	11.98	Yes	Yes	0	8	3
231	B:B:L7	G:G:L15	5.54	Yes	No	25	8	2
232	B:B:E10	G:G:L15	7.95	No	No	25	8	2
233	B:B:L14	G:G:Q18	5.32	No	No	0	8	9
234	B:B:N16	B:B:R19	7.23	No	No	0	1	4
235	B:B:Q17	G:G:E22	7.65	No	Yes	0	4	9
236	B:B:I18	B:B:R22	3.76	No	No	0	7	6
237	B:B:I18	G:G:M21	4.37	No	No	26	7	1
238	B:B:I18	G:G:E22	4.1	No	Yes	26	7	9
239	B:B:K23	B:B:R19	7.43	No	No	0	2	4
240	B:B:A21	G:G:R27	4.15	No	No	0	4	8
241	B:B:D258	B:B:R22	7.15	No	No	0	7	6
242	B:B:Q259	B:B:R22	7.01	Yes	No	0	6	6
243	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
244	B:B:C25	G:G:R27	11.14	No	No	0	3	8
245	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
246	B:B:A28	B:B:D27	3.09	No	No	0	4	8
247	B:B:D27	G:G:K29	9.68	No	No	0	8	4
248	B:B:S31	B:B:T29	4.8	No	No	27	1	3
249	B:B:Q32	B:B:T29	9.92	No	No	27	1	3
250	B:B:L30	B:B:T34	4.42	No	Yes	0	5	5
251	B:B:L30	B:B:M262	4.24	No	No	0	5	4
252	B:B:L30	G:G:A34	4.73	No	No	0	5	6
253	B:B:Q32	B:B:S31	5.78	No	No	27	1	1
254	B:B:I33	B:B:T34	3.04	No	Yes	0	3	5
255	B:B:I37	B:B:T34	3.04	Yes	Yes	0	2	5
256	B:B:L300	B:B:T34	4.42	Yes	Yes	0	6	5
257	B:B:I37	B:B:N36	4.25	Yes	No	0	2	1
258	B:B:I37	B:B:R283	3.76	Yes	No	0	2	9
259	B:B:D38	B:B:P39	3.22	No	No	0	1	1
260	B:B:G41	B:B:R42	6	No	No	0	1	2
261	B:B:I43	B:B:V296	3.07	No	Yes	0	3	5
262	B:B:L308	B:B:M45	9.9	No	No	0	7	4
263	B:B:M45	G:G:L50	4.24	No	No	0	4	9
264	B:B:R46	B:B:R48	14.93	No	No	0	5	7
265	B:B:K337	B:B:T47	9.01	Yes	No	7	6	3
266	B:B:T47	B:B:W339	8.49	No	Yes	7	3	9
267	B:B:N340	B:B:R48	7.23	No	No	0	9	7
268	B:B:R49	G:G:F61	6.41	No	Yes	0	7	8
269	B:B:R52	B:B:T50	9.06	No	No	0	7	3
270	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
271	B:B:L51	B:B:W82	15.94	No	Yes	11	9	9
272	B:B:L336	B:B:L51	5.54	No	No	11	7	9
273	B:B:F335	B:B:R52	5.34	No	No	0	4	7
274	B:B:H54	B:B:I58	9.28	Yes	No	11	9	9
275	B:B:H54	B:B:S72	5.58	Yes	Yes	11	9	9
276	B:B:H54	B:B:S74	9.76	Yes	No	0	9	9
277	B:B:H54	B:B:I80	13.26	Yes	Yes	11	9	8
278	B:B:H54	B:B:W82	7.41	Yes	Yes	11	9	9
279	B:B:D76	B:B:L55	10.86	No	Yes	0	9	6
280	B:B:K57	B:B:Y59	9.55	Yes	Yes	1	9	8
281	B:B:K57	B:B:Q75	6.78	Yes	Yes	1	9	9
282	B:B:K57	B:B:W332	12.76	Yes	Yes	1	9	9
283	B:B:I58	B:B:S72	3.1	No	Yes	11	9	9
284	B:B:Q75	B:B:Y59	18.04	Yes	Yes	1	9	8
285	B:B:M101	B:B:Y59	3.59	Yes	Yes	1	9	8
286	B:B:S316	B:B:Y59	3.82	No	Yes	1	9	8
287	B:B:W332	B:B:Y59	8.68	Yes	Yes	1	9	8
288	B:B:A60	B:B:T102	3.36	No	No	0	7	8
289	B:B:M61	B:B:W63	8.14	Yes	Yes	5	6	7
290	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
291	B:B:G319	B:B:M61	3.49	No	Yes	0	5	6
292	B:B:A328	B:B:M61	3.22	No	Yes	5	5	6
293	B:B:H62	B:B:Y105	3.27	No	No	0	6	6
294	B:B:H62	B:B:R150	13.54	No	No	0	6	6
295	B:B:L70	B:B:W63	13.67	No	Yes	0	5	7
296	B:B:S84	B:B:W63	4.94	No	Yes	5	5	7
297	B:B:T321	B:B:W63	13.34	No	Yes	5	7	7
298	B:B:A328	B:B:W63	3.89	No	Yes	5	5	7
299	B:B:S67	B:B:T321	4.8	No	No	5	5	7
300	B:B:D323	B:B:S67	8.83	No	No	5	7	5
301	B:B:L69	B:B:R68	3.64	No	No	5	5	5
302	B:B:D83	B:B:R68	17.87	No	No	5	8	5
303	B:B:R68	B:B:Y85	12.35	No	Yes	5	5	4
304	B:B:D83	B:B:L69	4.07	No	No	5	8	5
305	B:B:I81	B:B:V71	3.07	No	No	0	7	8
306	B:B:V112	B:B:V71	4.81	No	No	0	8	8
307	B:B:S72	B:B:W82	4.94	Yes	Yes	11	9	9
308	B:B:L336	B:B:S72	6.01	No	Yes	11	7	9
309	B:B:A73	B:B:L79	3.15	No	No	0	9	7
310	B:B:A73	B:B:V100	5.09	No	No	0	9	9
311	B:B:A73	B:B:C103	3.61	No	No	0	9	8
312	B:B:Q75	B:B:W99	6.57	Yes	Yes	0	9	9
313	B:B:Q75	B:B:V100	4.3	Yes	No	0	9	9
314	B:B:D76	B:B:K78	5.53	No	No	0	9	8
315	B:B:G77	B:B:L95	5.13	No	Yes	0	8	8
316	B:B:A92	B:B:K78	3.21	No	No	0	6	8
317	B:B:K78	B:B:P94	8.36	No	No	0	8	5
318	B:B:L79	B:B:L95	4.15	No	Yes	16	7	8
319	B:B:C114	B:B:L79	7.94	Yes	No	16	8	7
320	B:B:I80	B:B:W82	12.92	Yes	Yes	11	8	9
321	B:B:I80	B:B:K89	4.36	Yes	Yes	11	8	9
322	B:B:I81	B:B:L126	4.28	No	No	0	7	5
323	B:B:K89	B:B:W82	9.28	Yes	Yes	11	9	9
324	B:B:L336	B:B:W82	3.42	No	Yes	11	7	9
325	B:B:D83	B:B:T86	7.23	No	No	0	8	6
326	B:B:S84	B:B:Y85	3.82	No	Yes	5	5	4
327	B:B:S84	G:G:F61	6.61	No	Yes	5	5	8
328	B:B:Y85	G:G:P60	9.74	Yes	No	0	4	9
329	B:B:Y85	G:G:F61	5.16	Yes	Yes	5	4	8
330	B:B:N88	B:B:T86	10.24	No	No	0	7	6
331	B:B:H91	B:B:V90	6.92	Yes	No	0	5	5
332	B:B:H91	B:B:L126	7.71	Yes	No	0	5	5
333	B:B:H91	B:B:V133	4.15	Yes	No	0	5	4
334	B:B:I93	B:B:P94	3.39	No	No	0	7	5
335	B:B:I93	B:B:Y124	7.25	No	Yes	0	7	6
336	B:B:I93	B:B:V133	7.68	No	No	0	7	4
337	B:B:C114	B:B:L95	3.17	Yes	Yes	16	8	8
338	B:B:L95	B:B:Y124	3.52	Yes	Yes	16	8	6
339	B:B:D118	B:B:S97	10.31	No	No	0	9	8
340	B:B:L117	B:B:W99	4.56	No	Yes	0	9	9
341	B:B:G116	B:B:M101	3.49	No	Yes	0	9	9
342	B:B:M101	B:B:Y145	7.18	Yes	Yes	1	9	8
343	B:B:C148	B:B:T102	3.38	No	No	0	6	8
344	B:B:C149	B:B:T102	3.38	No	No	0	8	8
345	B:B:G109	B:B:Y105	4.35	No	No	0	5	6
346	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
347	B:B:N110	B:B:S108	5.96	Yes	No	28	4	6
348	B:B:D154	B:B:S108	7.36	No	No	28	6	6
349	B:B:G109	B:B:N110	3.39	No	Yes	0	5	4
350	B:B:K127	B:B:N110	8.39	No	Yes	0	4	4
351	B:B:D154	B:B:N110	9.42	No	Yes	28	6	4
352	B:B:N125	B:B:Y111	8.14	No	No	0	4	4
353	B:B:F151	B:B:Y111	3.09	Yes	No	0	9	4
354	B:B:D154	B:B:Y111	6.9	No	No	0	6	4
355	B:B:V112	B:B:Y124	3.79	No	Yes	0	8	6
356	B:B:C114	B:B:S122	3.44	Yes	No	16	8	8
357	B:B:C114	B:B:Y124	5.38	Yes	Yes	16	8	6
358	B:B:G144	B:B:N119	3.39	No	No	0	8	9
359	B:B:C121	B:B:L139	3.17	No	No	0	8	9
360	B:B:C121	B:B:L146	3.17	No	No	0	8	7
361	B:B:S122	B:B:Y124	6.36	No	Yes	16	8	6
362	B:B:I123	B:B:I171	5.89	No	No	0	6	6
363	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
364	B:B:N125	B:B:S136	8.94	No	No	0	4	4
365	B:B:G131	B:B:T128	3.64	No	No	0	4	3
366	B:B:E130	B:B:R129	6.98	No	No	0	3	3
367	B:B:N132	B:B:R134	3.62	No	No	0	3	3
368	B:B:E138	B:B:V135	4.28	No	No	0	6	4
369	B:B:G174	B:B:R137	6	No	No	0	4	5
370	B:B:L139	B:B:W169	13.67	No	Yes	0	9	8
371	B:B:H142	B:B:L146	5.14	Yes	No	9	9	7
372	B:B:H142	B:B:T159	5.48	Yes	Yes	9	9	9
373	B:B:H142	B:B:S161	16.74	Yes	No	9	9	9
374	B:B:H142	B:B:T165	4.11	Yes	Yes	9	9	7
375	B:B:H142	B:B:W169	9.52	Yes	Yes	9	9	8
376	B:B:G144	B:B:T143	3.64	No	No	0	8	5
377	B:B:D163	B:B:T143	10.12	No	No	0	9	5
378	B:B:G162	B:B:Y145	5.79	No	Yes	0	9	8
379	B:B:D186	B:B:Y145	5.75	Yes	Yes	1	9	8
380	B:B:M188	B:B:Y145	4.79	No	Yes	1	8	8
381	B:B:L146	B:B:T159	4.42	No	Yes	9	7	9
382	B:B:S147	B:B:S160	4.89	No	No	0	9	6
383	B:B:C148	B:B:R150	6.96	No	No	0	6	6
384	B:B:C148	B:B:L190	3.17	No	Yes	0	6	5
385	B:B:C149	B:B:T159	5.07	No	Yes	0	8	9
386	B:B:F151	B:B:I157	6.28	Yes	No	0	9	7
387	B:B:L152	B:B:Q156	6.65	No	No	0	3	5
388	B:B:D153	B:B:N155	4.04	No	No	0	5	3
389	B:B:D153	B:B:Q156	7.83	No	No	0	5	5
390	B:B:D170	B:B:N155	10.77	No	No	29	9	3
391	B:B:E172	B:B:N155	14.46	No	No	29	6	3
392	B:B:L168	B:B:Q156	5.32	No	No	0	6	5
393	B:B:I157	B:B:T159	3.04	No	Yes	0	7	9
394	B:B:L190	B:B:V158	4.47	Yes	No	0	5	5
395	B:B:T159	B:B:W169	9.7	Yes	Yes	9	9	8
396	B:B:S160	B:B:V187	4.85	No	Yes	0	6	9
397	B:B:L190	B:B:S160	4.5	Yes	No	0	5	6
398	B:B:D163	B:B:S161	7.36	No	No	9	9	9
399	B:B:S161	B:B:T165	4.8	No	Yes	9	9	7
400	B:B:D163	B:B:T165	13.01	No	Yes	9	9	7
401	B:B:C166	B:B:V187	3.42	No	Yes	6	8	9
402	B:B:C166	B:B:S201	3.44	No	Yes	6	8	9
403	B:B:A167	B:B:W169	5.19	No	Yes	9	4	8
404	B:B:A167	B:B:Q176	6.06	No	Yes	9	4	4
405	B:B:L168	B:B:T177	4.42	No	No	0	6	4
406	B:B:Q176	B:B:W169	14.24	Yes	Yes	9	4	8
407	B:B:D170	B:B:E172	14.29	No	No	29	9	6
408	B:B:D170	B:B:T173	10.12	No	No	0	9	5
409	B:B:G174	B:B:Q175	3.29	No	No	0	4	4
410	B:B:T177	B:B:T178	4.71	No	No	0	4	4
411	B:B:F180	B:B:T178	5.19	Yes	No	0	7	4
412	B:B:F180	B:B:F199	7.5	Yes	Yes	6	7	9
413	B:B:F180	B:B:W211	14.03	Yes	Yes	6	7	8
414	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
415	B:B:H183	B:B:V187	8.3	Yes	Yes	6	9	9
416	B:B:H183	B:B:S201	5.58	Yes	Yes	6	9	9
417	B:B:A203	B:B:H183	8.78	No	Yes	6	8	9
418	B:B:H183	B:B:S207	6.97	Yes	Yes	6	9	5
419	B:B:H183	B:B:K209	19.65	Yes	Yes	6	9	6
420	B:B:H183	B:B:W211	4.23	Yes	Yes	6	9	8
421	B:B:D205	B:B:T184	10.12	No	No	0	9	3
422	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
423	B:B:S201	B:B:V187	3.23	Yes	Yes	6	9	9
424	B:B:A203	B:B:V187	3.39	No	Yes	6	8	9
425	B:B:C204	B:B:M188	3.24	Yes	No	1	7	8
426	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
427	B:B:F199	B:B:L190	6.09	Yes	Yes	0	9	5
428	B:B:F234	B:B:S191	3.96	No	No	0	5	8
429	B:B:F199	B:B:L192	4.87	Yes	No	0	9	5
430	B:B:A193	B:B:D195	3.09	No	No	0	4	5
431	B:B:G238	B:B:P194	4.06	No	No	0	7	4
432	B:B:D195	B:B:R197	5.96	No	No	0	5	5
433	B:B:R197	B:B:R214	10.66	No	No	0	5	9
434	B:B:L198	B:B:L210	5.54	No	Yes	0	3	5
435	B:B:F199	B:B:W211	9.02	Yes	Yes	6	9	8
436	B:B:L210	B:B:V200	4.47	Yes	No	0	5	6
437	B:B:I232	B:B:V200	6.14	Yes	No	0	8	6
438	B:B:F234	B:B:V200	9.18	No	No	0	5	6
439	B:B:S201	B:B:W211	7.41	Yes	Yes	6	9	8
440	B:B:G202	B:B:I229	5.29	No	No	0	6	7
441	B:B:A203	B:B:D205	3.09	No	No	0	8	9
442	B:B:C204	B:B:D228	12.45	Yes	No	1	7	9
443	B:B:D205	B:B:S207	10.31	No	Yes	0	9	5
444	B:B:K209	B:B:S207	3.06	Yes	Yes	6	6	5
445	B:B:K209	B:B:W211	9.28	Yes	Yes	6	6	8
446	B:B:C218	B:B:K209	6.47	No	Yes	6	5	6
447	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
448	B:B:L210	B:B:R219	6.07	Yes	Yes	2	5	5
449	B:B:L210	B:B:Q220	5.32	Yes	Yes	2	5	7
450	B:B:L210	B:B:L255	5.54	Yes	No	0	5	6
451	B:B:C218	B:B:W211	5.22	No	Yes	6	5	8
452	B:B:D212	B:B:E215	12.99	No	No	2	9	3
453	B:B:D212	B:B:M217	8.32	No	Yes	2	9	3
454	B:B:D212	B:B:R219	5.96	No	Yes	2	9	5
455	B:B:R214	B:B:V213	5.23	No	No	0	9	4
456	B:B:E215	B:B:R214	3.49	No	No	0	3	9
457	B:B:E215	B:B:M217	4.06	No	Yes	2	3	3
458	B:B:M217	B:B:R219	9.93	Yes	Yes	2	3	5
459	B:B:C218	G:G:E17	3.04	No	No	0	5	6
460	B:B:Q220	B:B:R219	4.67	Yes	Yes	2	7	5
461	B:B:F222	B:B:Q220	8.2	No	Yes	2	8	7
462	B:B:D258	B:B:Q220	11.75	No	Yes	0	7	7
463	B:B:F222	B:B:F241	13.93	No	Yes	2	8	6
464	B:B:F222	B:B:F253	10.72	No	Yes	2	8	6
465	B:B:H225	B:B:I229	3.98	Yes	No	2	9	7
466	B:B:H225	B:B:T243	8.21	Yes	Yes	2	9	8
467	B:B:H225	B:B:S245	11.16	Yes	No	2	9	9
468	B:B:D247	B:B:H225	11.35	Yes	Yes	2	9	9
469	B:B:H225	B:B:T249	8.21	Yes	Yes	2	9	6
470	B:B:H225	B:B:R251	18.05	Yes	Yes	2	9	8
471	B:B:D247	B:B:E226	10.39	Yes	No	0	9	3
472	B:B:S227	B:B:S245	4.89	No	No	2	6	9
473	B:B:D247	B:B:S227	8.83	Yes	No	2	9	6
474	B:B:I229	B:B:T243	4.56	No	Yes	2	7	8
475	B:B:D246	B:B:N230	10.77	No	No	0	9	9
476	B:B:A231	B:B:V276	3.39	No	No	0	5	6
477	B:B:F241	B:B:I232	5.02	Yes	Yes	0	6	8
478	B:B:I232	B:B:T243	4.56	Yes	Yes	0	8	8
479	B:B:F234	B:B:F241	5.36	No	Yes	0	5	6
480	B:B:F235	B:B:P236	13	Yes	No	19	6	7
481	B:B:F235	B:B:F278	9.65	Yes	No	0	6	7
482	B:B:F235	B:B:G282	4.52	Yes	No	19	6	9
483	B:B:F235	G:G:L37	7.31	Yes	No	0	6	7
484	B:B:F235	G:G:Y40	5.16	Yes	Yes	19	6	6
485	B:B:G282	B:B:P236	4.06	No	No	19	9	7
486	B:B:P236	G:G:Y40	5.56	No	Yes	19	7	6
487	B:B:N237	G:G:Y40	16.28	No	Yes	0	5	6
488	B:B:N239	B:B:R256	15.67	No	No	0	2	9
489	B:B:F241	B:B:F253	10.72	Yes	Yes	2	6	6
490	B:B:F241	B:B:L255	3.65	Yes	No	0	6	6
491	B:B:A242	B:B:L285	3.15	No	No	0	4	6
492	B:B:F253	B:B:T243	7.78	Yes	Yes	2	6	8
493	B:B:G244	B:B:I273	3.53	No	No	0	5	6
494	B:B:D247	B:B:S245	10.31	Yes	No	2	9	9
495	B:B:D247	B:B:T249	11.56	Yes	Yes	2	9	6
496	B:B:R251	B:B:T249	9.06	Yes	Yes	2	8	6
497	B:B:S265	B:B:T249	4.8	No	Yes	0	2	6
498	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
499	B:B:C250	B:B:I273	6.55	No	No	0	8	6
500	B:B:F253	B:B:R251	4.28	Yes	Yes	2	6	8
501	B:B:E260	B:B:R251	6.98	No	Yes	2	6	8
502	B:B:R251	B:B:T263	6.47	Yes	No	2	8	1
503	B:B:L252	B:B:L261	4.15	No	No	0	7	5
504	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
505	B:B:E260	B:B:F253	5.83	No	Yes	2	6	6
506	B:B:A257	B:B:D254	4.63	No	No	0	7	9
507	B:B:D254	B:B:L261	5.43	No	No	0	9	5
508	B:B:D254	G:G:A33	3.09	No	No	0	9	7
509	B:B:R256	G:G:I28	7.52	No	No	0	9	4
510	B:B:R256	G:G:D36	5.96	No	No	0	9	5
511	B:B:E260	B:B:T263	5.64	No	No	2	6	1
512	B:B:M262	B:B:Y264	8.38	No	Yes	0	4	5
513	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
514	B:B:W297	B:B:Y264	6.75	No	Yes	0	8	5
515	B:B:H266	B:B:N268	3.83	No	No	1	4	4
516	B:B:H266	B:B:R304	5.64	No	Yes	1	4	5
517	B:B:N268	B:B:R304	3.62	No	Yes	1	4	5
518	B:B:I269	B:B:Y289	4.84	No	Yes	1	4	7
519	B:B:D291	B:B:I269	4.2	Yes	No	1	8	4
520	B:B:C271	B:B:Y289	4.03	Yes	Yes	1	5	7
521	B:B:C271	B:B:D290	3.11	Yes	Yes	1	5	6
522	B:B:C271	B:B:D291	7.78	Yes	Yes	1	5	8
523	B:B:I273	B:B:Y289	13.3	No	Yes	0	6	7
524	B:B:S275	B:B:T274	3.2	No	No	0	8	8
525	B:B:D290	B:B:T274	5.78	Yes	No	1	6	8
526	B:B:R314	B:B:T274	7.76	Yes	No	1	8	8
527	B:B:S277	B:B:V320	4.85	No	No	0	5	7
528	B:B:F278	B:B:L285	8.53	No	No	0	7	6
529	B:B:S279	B:B:S281	3.26	No	No	13	9	9
530	B:B:S279	G:G:D48	5.89	No	Yes	13	9	9
531	B:B:S281	G:G:D48	10.31	No	Yes	13	9	9
532	B:B:L300	B:B:R283	6.07	Yes	No	0	6	9
533	B:B:R283	G:G:L51	9.72	No	Yes	0	9	6
534	B:B:L284	G:G:L51	4.15	No	Yes	13	5	6
535	B:B:L286	B:B:V296	5.96	No	Yes	0	7	5
536	B:B:L286	B:B:V327	5.96	No	No	0	7	6
537	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
538	B:B:C294	B:B:G288	3.92	Yes	No	7	5	7
539	B:B:G288	B:B:V315	3.68	No	No	7	7	7
540	B:B:D291	B:B:Y289	3.45	Yes	Yes	1	8	7
541	B:B:N295	B:B:Y289	13.96	Yes	Yes	1	6	7
542	B:B:W297	B:B:Y289	6.75	No	Yes	1	8	7
543	B:B:D290	B:B:R314	16.68	Yes	Yes	1	6	8
544	B:B:D291	B:B:N293	6.73	Yes	No	0	8	5
545	B:B:A309	B:B:N293	4.69	No	No	0	3	5
546	B:B:C294	B:B:V315	5.12	Yes	No	7	5	7
547	B:B:C294	B:B:T329	3.38	Yes	Yes	7	5	8
548	B:B:C294	B:B:W339	3.92	Yes	Yes	7	5	9
549	B:B:N295	B:B:W297	5.65	Yes	No	1	6	8
550	B:B:N295	B:B:R304	4.82	Yes	Yes	1	6	5
551	B:B:N295	B:B:V307	5.91	Yes	No	1	6	3
552	B:B:D298	B:B:K301	8.3	No	Yes	30	9	5
553	B:B:D298	B:B:D303	7.98	No	No	30	9	2
554	B:B:L300	G:G:C41	3.17	Yes	No	0	6	7
555	B:B:D303	B:B:K301	8.3	No	Yes	30	2	5
556	B:B:R304	B:B:V307	3.92	Yes	No	1	5	3
557	B:B:L308	B:B:W339	10.25	No	Yes	0	7	9
558	B:B:H311	B:B:T329	6.85	Yes	Yes	7	9	8
559	B:B:H311	B:B:S331	12.55	Yes	No	7	9	9
560	B:B:D333	B:B:H311	7.56	Yes	Yes	7	9	9
561	B:B:H311	B:B:K337	7.86	Yes	Yes	7	9	6
562	B:B:H311	B:B:W339	4.23	Yes	Yes	7	9	9
563	B:B:D312	B:B:D333	6.65	No	Yes	0	5	9
564	B:B:N313	B:B:W332	3.39	No	Yes	0	7	9
565	B:B:R314	B:B:W332	22.99	Yes	Yes	1	8	9
566	B:B:T329	B:B:V315	4.76	Yes	No	7	8	7
567	B:B:S316	B:B:W332	4.94	No	Yes	1	9	9
568	B:B:L318	B:B:T329	4.42	No	Yes	0	6	8
569	B:B:V320	B:B:V327	4.81	No	No	0	7	6
570	B:B:D323	B:B:T321	10.12	No	No	5	7	7
571	B:B:D323	B:B:M325	5.54	No	No	0	7	5
572	B:B:M325	G:G:P49	3.35	No	No	0	5	7
573	B:B:M325	G:G:P60	6.71	No	No	0	5	9
574	B:B:A326	G:G:F61	5.55	No	Yes	0	7	8
575	B:B:T329	B:B:W339	13.34	Yes	Yes	7	8	9
576	B:B:D333	B:B:S331	5.89	Yes	No	7	9	9
577	B:B:D333	B:B:F335	11.94	Yes	No	0	9	4
578	B:B:K337	B:B:W339	9.28	Yes	Yes	7	6	9
579	B:B:I338	G:G:F61	3.77	No	Yes	0	5	8
580	B:B:N340	G:G:N59	5.45	No	No	0	9	9
581	B:B:N340	G:G:F61	4.83	No	Yes	0	9	8
582	G:G:R13	G:G:V16	6.54	No	No	0	6	7
583	G:G:K14	G:G:Q18	9.49	No	No	0	4	9
584	G:G:M21	G:G:Q18	6.8	No	No	0	1	9
585	G:G:E22	G:G:M21	4.06	Yes	No	26	9	1
586	G:G:E22	G:G:I25	5.47	Yes	No	0	9	2
587	G:G:I25	G:G:R27	3.76	No	No	0	2	8
588	G:G:I28	G:G:K32	7.27	No	No	0	4	5
589	G:G:K29	G:G:S31	3.06	No	No	0	4	9
590	G:G:K29	G:G:K32	4.31	No	No	0	4	5
591	G:G:H44	G:G:Y40	23.96	No	Yes	0	6	6
592	G:G:A43	G:G:E42	3.02	No	No	0	4	1
593	G:G:E47	G:G:H44	7.39	No	No	0	3	6
594	G:G:D48	G:G:P49	6.44	Yes	No	0	9	7
595	G:G:D48	G:G:L51	8.14	Yes	Yes	13	9	6
596	G:G:N59	G:G:V54	4.43	No	No	0	9	6
597	G:G:E58	G:G:P55	15.72	No	No	0	5	5
598	G:G:E58	G:G:S57	5.75	No	No	0	5	6
599	R:R:C165	R:R:P166	3.77	No	No	0	9	6
600	R:R:C165	R:R:C185	7.28	No	No	0	9	9
601	R:R:E168	R:R:P166	6.29	No	No	31	5	6
602	R:R:L169	R:R:P166	6.57	No	No	31	6	6
603	R:R:H462	R:R:R167	11.28	No	No	0	6	3
604	R:R:E168	R:R:L169	10.6	No	No	31	5	6
605	R:R:E168	R:R:Y461	10.1	No	No	0	5	4
606	R:R:L169	R:R:P188	6.57	No	No	0	6	5
607	R:R:D184	R:R:K170	11.06	No	No	0	6	5
608	R:R:I171	R:R:Y177	12.09	No	Yes	0	4	6
609	R:R:D184	R:R:I171	5.6	No	No	0	6	4
610	R:R:G176	R:R:R183	9.01	No	No	0	2	3
611	R:R:S186	R:R:Y177	6.36	No	Yes	0	6	6
612	R:R:Q279	R:R:Y177	24.8	Yes	Yes	0	7	6
613	R:R:H282	R:R:Y177	7.62	No	Yes	0	6	6
614	R:R:Q279	R:R:S178	5.78	Yes	No	0	7	3
615	R:R:D367	R:R:S178	4.42	Yes	No	0	6	3
616	R:R:F179	R:R:L180	7.31	No	No	0	5	4
617	R:R:F179	R:R:P187	13	No	Yes	0	5	5
618	R:R:F179	R:R:P188	4.33	No	No	0	5	5
619	R:R:C185	R:R:V182	3.42	No	No	0	9	5
620	R:R:P187	R:R:S186	3.56	Yes	No	0	5	6
621	R:R:S186	R:R:T276	9.59	No	No	0	6	5
622	R:R:P187	R:R:V277	7.07	Yes	No	0	5	6
623	R:R:P187	R:R:Y366	9.74	Yes	No	0	5	5
624	R:R:M192	R:R:P188	5.03	No	No	0	7	5
625	R:R:C189	R:R:P190	7.53	No	No	0	9	3
626	R:R:C189	R:R:C264	7.28	No	No	0	9	9
627	R:R:N191	R:R:P190	8.15	No	No	0	4	3
628	R:R:M192	R:R:Y193	4.79	No	No	0	7	5
629	R:R:M192	R:R:N356	7.01	No	Yes	0	7	6
630	R:R:W453	R:R:Y193	6.75	No	No	0	5	5
631	R:R:P475	R:R:Y193	4.17	Yes	No	0	8	5
632	R:R:F194	R:R:P475	5.78	No	Yes	0	6	8
633	R:R:F194	R:R:L477	7.31	No	No	0	6	5
634	R:R:F194	R:R:F480	4.29	No	No	0	6	6
635	R:R:R195	R:R:R196	6.4	No	No	32	4	4
636	R:R:E198	R:R:R195	8.14	No	No	32	7	4
637	R:R:E197	R:R:R196	6.98	No	No	0	4	4
638	R:R:E198	R:R:R196	5.82	No	No	32	7	4
639	R:R:E197	R:R:S200	7.19	No	No	0	4	3
640	R:R:E198	R:R:L477	9.28	No	No	0	7	5
641	R:R:F256	R:R:R203	19.24	No	No	0	6	7
642	R:R:F205	R:R:I209	5.02	No	Yes	0	7	5
643	R:R:F205	R:R:L481	17.05	No	No	0	7	8
644	R:R:I206	R:R:S358	4.64	No	No	0	7	8
645	R:R:G207	R:R:S210	3.71	No	No	0	6	8
646	R:R:I209	R:R:L485	8.56	Yes	No	0	5	7
647	R:R:C213	R:R:L214	4.76	No	No	33	8	4
648	R:R:C213	R:R:S249	3.44	No	No	33	8	8
649	R:R:C213	R:R:L488	4.76	No	No	0	8	8
650	R:R:L214	R:R:S249	6.01	No	No	33	4	8
651	R:R:F253	R:R:L214	4.87	No	No	0	5	4
652	R:R:T217	R:R:T220	7.85	Yes	No	10	8	8
653	R:R:A242	R:R:T217	5.03	No	Yes	10	8	8
654	R:R:M246	R:R:T217	4.52	No	Yes	0	5	8
655	R:R:S494	R:R:T217	7.99	Yes	Yes	10	8	8
656	R:R:S494	R:R:T220	3.2	Yes	No	10	8	8
657	R:R:T220	R:R:V495	3.17	No	Yes	0	8	8
658	R:R:A242	R:R:F221	4.16	No	Yes	0	8	7
659	R:R:F221	R:R:V243	6.55	Yes	No	0	7	5
660	R:R:F221	R:R:M246	4.98	Yes	No	0	7	5
661	R:R:F224	R:R:V228	6.55	No	No	0	9	6
662	R:R:F224	R:R:F231	3.22	No	No	0	9	9
663	R:R:F224	R:R:I239	8.79	No	No	0	9	8
664	R:R:D227	R:R:I226	5.6	No	No	0	8	7
665	R:R:I226	R:R:K502	7.27	No	No	0	7	9
666	R:R:D227	R:R:R230	5.96	No	No	0	8	9
667	R:R:F231	R:R:R230	9.62	No	No	0	9	9
668	R:R:R232	R:R:S321	6.59	No	No	0	6	6
669	R:R:R236	R:R:Y233	10.29	No	Yes	0	9	9
670	R:R:T310	R:R:Y233	4.99	No	Yes	0	8	9
671	R:R:I324	R:R:Y233	7.25	No	Yes	0	9	9
672	R:R:E325	R:R:Y233	5.61	No	Yes	0	7	9
673	R:R:A328	R:R:Y233	6.67	No	Yes	0	8	9
674	R:R:F331	R:R:Y233	7.22	No	Yes	0	8	9
675	R:R:A314	R:R:P234	3.74	No	No	0	8	9
676	R:R:P234	R:R:S321	7.13	No	No	0	9	6
677	R:R:I324	R:R:P234	3.39	No	No	0	9	9
678	R:R:E235	R:R:W497	11.99	No	Yes	0	9	9
679	R:R:F240	R:R:R236	6.41	Yes	No	0	8	9
680	R:R:P237	R:R:W303	5.4	No	Yes	14	8	9
681	R:R:I306	R:R:P237	3.39	No	No	14	7	8
682	R:R:I238	R:R:S494	3.1	No	Yes	0	9	8
683	R:R:I238	R:R:W497	3.52	No	Yes	0	9	9
684	R:R:F240	R:R:I239	7.54	Yes	No	0	8	8
685	R:R:F240	R:R:W303	22.05	Yes	Yes	14	8	9
686	R:R:F240	R:R:H332	3.39	Yes	No	14	8	9
687	R:R:Y241	R:R:Y245	5.96	Yes	No	0	8	8
688	R:R:Y241	R:R:Y428	9.93	Yes	Yes	10	8	8
689	R:R:P493	R:R:Y241	8.34	Yes	Yes	10	8	8
690	R:R:S494	R:R:Y241	5.09	Yes	Yes	10	8	8
691	R:R:A242	R:R:S494	3.42	No	Yes	10	8	8
692	R:R:C244	R:R:F296	4.19	No	No	0	9	8
693	R:R:A299	R:R:C244	3.61	No	No	0	9	9
694	R:R:C244	R:R:G300	3.92	No	No	0	9	8
695	R:R:G300	R:R:Y245	4.35	No	No	0	8	8
696	R:R:V490	R:R:Y245	5.05	No	No	0	8	8
697	R:R:M246	R:R:S249	9.2	No	No	0	5	8
698	R:R:F296	R:R:M247	9.95	No	No	0	8	5
699	R:R:L293	R:R:V248	4.47	No	No	0	6	7
700	R:R:T297	R:R:V248	6.35	No	No	0	6	7
701	R:R:I251	R:R:L289	5.71	No	No	0	6	7
702	R:R:I251	R:R:I292	5.89	No	No	0	6	5
703	R:R:I251	R:R:L293	11.42	No	No	0	6	6
704	R:R:F252	R:R:S358	5.28	No	No	0	8	8
705	R:R:F252	R:R:L488	3.65	No	No	0	8	8
706	R:R:F253	R:R:L257	8.53	No	No	0	5	4
707	R:R:L258	R:R:V262	8.94	No	No	0	4	6
708	R:R:D260	R:R:E259	5.2	No	No	0	6	6
709	R:R:E259	R:R:R261	3.49	No	No	0	6	3
710	R:R:N265	R:R:S275	4.47	No	No	0	4	3
711	R:R:N283	R:R:T278	4.39	No	Yes	0	7	6
712	R:R:G280	R:R:Q279	3.29	No	Yes	0	6	7
713	R:R:E353	R:R:Q279	5.1	No	Yes	0	7	7
714	R:R:G280	R:R:H282	4.77	No	No	0	6	6
715	R:R:S281	R:R:T287	3.2	No	Yes	3	6	7
716	R:R:N350	R:R:S281	4.47	No	No	0	6	6
717	R:R:I352	R:R:S281	4.64	Yes	No	3	8	6
718	R:R:C286	R:R:I352	4.91	No	Yes	3	9	8
719	R:R:C286	R:R:C361	7.28	No	No	3	9	9
720	R:R:M288	R:R:T287	3.01	No	Yes	0	5	7
721	R:R:I352	R:R:T287	3.04	Yes	Yes	3	8	7
722	R:R:C361	R:R:L289	3.17	No	No	0	9	7
723	R:R:F290	R:R:M291	3.73	Yes	No	0	9	7
724	R:R:F290	R:R:Y294	8.25	Yes	Yes	3	9	9
725	R:R:F290	R:R:L346	6.09	Yes	Yes	3	9	7
726	R:R:F290	R:R:I352	10.05	Yes	Yes	3	9	8
727	R:R:F290	R:R:V363	5.24	Yes	Yes	3	9	9
728	R:R:L347	R:R:M291	7.07	No	No	0	8	7
729	R:R:M298	R:R:Y294	10.78	No	Yes	0	7	9
730	R:R:L346	R:R:Y294	5.86	Yes	Yes	3	7	9
731	R:R:F362	R:R:Y294	7.22	No	Yes	0	7	9
732	R:R:F295	R:R:F296	8.57	Yes	No	0	8	8
733	R:R:F295	R:R:W336	5.01	Yes	No	0	8	9
734	R:R:F295	R:R:P339	7.22	Yes	Yes	0	8	9
735	R:R:F295	R:R:G340	3.01	Yes	No	0	8	7
736	R:R:F295	R:R:T343	10.38	Yes	No	0	8	9
737	R:R:M298	R:R:T297	3.01	No	No	0	7	6
738	R:R:M298	R:R:P339	3.35	No	Yes	0	7	9
739	R:R:S301	R:R:Y382	6.36	No	Yes	0	6	5
740	R:R:P339	R:R:V302	3.53	Yes	No	0	9	5
741	R:R:V302	R:R:Y382	6.31	No	Yes	0	5	5
742	R:R:I306	R:R:W303	7.05	No	Yes	14	7	9
743	R:R:H332	R:R:W303	8.46	No	Yes	14	9	9
744	R:R:A335	R:R:W303	9.08	No	Yes	0	9	9
745	R:R:W303	R:R:W336	14.06	Yes	No	14	9	9
746	R:R:T308	R:R:W304	7.28	No	No	0	7	9
747	R:R:W304	R:R:Y428	24.12	No	Yes	0	9	8
748	R:R:V305	R:R:Y382	3.79	No	Yes	0	8	5
749	R:R:V305	R:R:V385	3.21	No	No	0	8	4
750	R:R:F331	R:R:I306	3.77	No	No	0	8	7
751	R:R:G386	R:R:T308	5.46	No	No	0	9	7
752	R:R:F331	R:R:I309	3.77	No	No	0	8	6
753	R:R:L390	R:R:W311	4.56	No	Yes	0	8	9
754	R:R:G393	R:R:W311	4.22	No	Yes	0	9	9
755	R:R:F417	R:R:W311	5.01	No	Yes	0	8	9
756	R:R:F312	R:R:L313	3.65	No	No	0	7	8
757	R:R:F312	R:R:V316	6.55	No	No	0	7	7
758	R:R:F312	R:R:L389	10.96	No	No	0	7	8
759	R:R:I324	R:R:L313	4.28	No	No	0	9	8
760	R:R:P317	R:R:V316	5.3	No	No	0	7	7
761	R:R:S396	R:R:V316	9.7	No	No	0	8	7
762	R:R:P317	R:R:W319	8.11	No	No	0	7	8
763	R:R:K326	R:R:K327	4.31	No	No	0	5	6
764	R:R:H332	R:R:W336	7.41	No	No	14	9	9
765	R:R:I338	R:R:S334	3.1	No	No	0	4	5
766	R:R:I338	R:R:P339	3.39	No	Yes	0	4	9
767	R:R:I344	R:R:T343	3.04	No	No	0	7	9
768	R:R:L346	R:R:V363	7.45	Yes	Yes	3	7	9
769	R:R:F374	R:R:L346	17.05	No	Yes	0	8	7
770	R:R:I352	R:R:L347	4.28	Yes	No	0	8	8
771	R:R:K351	R:R:M349	8.64	No	No	0	6	4
772	R:R:A370	R:R:K351	4.82	No	No	0	6	6
773	R:R:E353	R:R:G364	3.27	No	Yes	3	7	8
774	R:R:D367	R:R:E353	9.09	Yes	No	3	6	7
775	R:R:D355	R:R:N356	4.04	Yes	Yes	20	9	6
776	R:R:D355	R:R:I357	5.6	Yes	Yes	20	9	8
777	R:R:D355	R:R:V360	4.38	Yes	No	0	9	7
778	R:R:D355	R:R:L365	4.07	Yes	No	0	9	6
779	R:R:D355	R:R:Y484	11.49	Yes	No	20	9	8
780	R:R:I357	R:R:N356	8.5	Yes	Yes	20	8	6
781	R:R:N356	R:R:Y366	3.49	Yes	No	0	6	5
782	R:R:I357	R:R:Y484	6.04	Yes	No	20	8	8
783	R:R:F362	R:R:V363	5.24	No	Yes	0	7	9
784	R:R:F362	R:R:L365	3.65	No	No	0	7	6
785	R:R:G364	R:R:V363	3.68	Yes	Yes	3	8	9
786	R:R:D367	R:R:G364	5.03	Yes	Yes	3	6	8
787	R:R:G364	R:R:L371	5.13	Yes	Yes	3	8	8
788	R:R:A370	R:R:D367	4.63	No	Yes	0	6	6
789	R:R:D369	R:R:V368	4.38	No	No	0	2	3
790	R:R:R372	R:R:V368	5.23	No	No	0	6	3
791	R:R:D369	R:R:Y373	3.45	No	No	0	2	2
792	R:R:L371	R:R:V375	5.96	Yes	No	3	8	7
793	R:R:L371	R:R:Y439	3.52	Yes	Yes	3	8	5
794	R:R:L371	R:R:Q443	5.32	Yes	No	0	8	5
795	R:R:Q443	R:R:R372	12.85	No	No	0	5	6
796	R:R:V375	R:R:Y439	3.79	No	Yes	3	7	5
797	R:R:L376	R:R:Y439	7.03	No	Yes	0	6	5
798	R:R:F440	R:R:L376	4.87	No	No	0	4	6
799	R:R:C380	R:R:I436	3.27	No	No	0	3	6
800	R:R:L429	R:R:V387	4.47	No	No	0	7	6
801	R:R:L389	R:R:S388	6.01	No	No	0	8	3
802	R:R:I394	R:R:M418	4.37	No	Yes	0	7	8
803	R:R:L397	R:R:M418	7.07	No	Yes	0	8	8
804	R:R:N398	R:R:R401	4.82	No	No	0	6	9
805	R:R:I404	R:R:V400	3.07	Yes	Yes	0	7	8
806	R:R:Q411	R:R:R401	9.35	Yes	No	0	7	9
807	R:R:M418	R:R:R401	4.96	Yes	No	0	8	9
808	R:R:I404	R:R:P405	3.39	Yes	No	34	7	7
809	R:R:E409	R:R:I404	5.47	No	Yes	0	6	7
810	R:R:I404	R:R:Q411	8.23	Yes	Yes	34	7	7
811	R:R:P405	R:R:Q411	20.53	No	Yes	34	7	7
812	R:R:E409	R:R:K408	21.6	No	No	0	6	7
813	R:R:D412	R:R:N410	16.16	No	No	0	4	7
814	R:R:L414	R:R:Q411	7.99	No	Yes	0	9	7
815	R:R:Q411	R:R:V415	4.3	Yes	No	0	7	8
816	R:R:M418	R:R:V415	3.04	Yes	No	0	8	8
817	R:R:I419	R:R:K416	5.82	No	No	0	5	7
818	R:R:F417	R:R:W497	3.01	No	Yes	0	8	9
819	R:R:R420	R:R:W497	19.99	No	Yes	0	9	9
820	R:R:I421	R:R:W497	4.7	No	Yes	0	8	9
821	R:R:F496	R:R:V423	5.24	No	No	0	6	6
822	R:R:F424	R:R:P493	7.22	No	Yes	0	9	8
823	R:R:F424	R:R:F496	5.36	No	No	0	9	6
824	R:R:F424	R:R:W497	11.02	No	Yes	0	9	9
825	R:R:I492	R:R:L427	5.71	No	No	10	8	7
826	R:R:L427	R:R:P493	4.93	No	Yes	10	7	8
827	R:R:L432	R:R:Y428	4.69	No	Yes	0	7	8
828	R:R:P493	R:R:Y428	5.56	Yes	Yes	10	8	8
829	R:R:L429	R:R:L433	4.15	No	No	0	7	4
830	R:R:P431	R:R:V430	3.53	No	No	0	9	5
831	R:R:M486	R:R:P431	3.35	No	No	0	7	9
832	R:R:M482	R:R:V434	3.04	No	No	0	6	5
833	R:R:M486	R:R:V434	6.09	No	No	0	7	5
834	R:R:V435	R:R:Y439	5.05	No	Yes	0	7	5
835	R:R:C438	R:R:K483	6.47	No	Yes	0	7	8
836	R:R:K483	R:R:Y439	3.58	Yes	Yes	0	8	5
837	R:R:Y441	R:R:Y445	7.94	No	No	0	9	4
838	R:R:W449	R:R:Y441	8.68	Yes	No	0	9	9
839	R:R:L479	R:R:Y441	8.21	No	No	0	6	9
840	R:R:E442	R:R:R446	4.65	No	No	0	9	6
841	R:R:A444	R:R:Y445	4	No	No	0	3	4
842	R:R:E450	R:R:R446	4.65	No	No	0	6	6
843	R:R:E450	R:R:G447	4.91	No	No	0	6	3
844	R:R:I448	R:R:S473	4.64	No	No	0	3	3
845	R:R:S473	R:R:W449	6.18	No	Yes	0	3	9
846	R:R:P475	R:R:W449	20.27	Yes	Yes	0	8	9
847	R:R:F480	R:R:W449	5.01	No	Yes	0	6	9
848	R:R:M472	R:R:T452	3.01	No	No	0	1	5
849	R:R:R457	R:R:W453	20.99	No	No	0	4	5
850	R:R:I454	R:R:P466	3.39	No	No	0	3	5
851	R:R:P466	R:R:Q455	7.9	No	No	0	5	3
852	R:R:E456	R:R:R457	10.47	No	No	0	4	4
853	R:R:E460	R:R:R457	13.96	No	No	0	3	4
854	R:R:C458	R:R:C465	7.28	No	No	35	9	9
855	R:R:I463	R:R:P464	5.08	No	No	0	5	5
856	R:R:D476	R:R:L479	6.79	No	No	0	5	6
857	R:R:F480	R:R:L479	3.65	No	No	0	6	6
858	R:R:K483	R:R:Y484	8.36	Yes	No	0	8	8
859	R:R:I492	R:R:P493	3.39	No	Yes	10	8	8
860	A:A:K58	A:A:T55	3	No	No	0	9	9
861	A:A:G355	A:A:R356	3	No	Yes	0	2	2
862	B:B:L318	B:B:S275	3	No	No	0	6	8
863	R:R:L379	R:R:S301	3	No	No	0	7	6
864	R:R:L390	R:R:S425	3	No	No	0	8	8
865	B:B:L284	B:B:V40	2.98	No	No	13	5	3
866	B:B:V40	G:G:L51	2.98	No	Yes	13	3	6
867	B:B:L168	B:B:V213	2.98	No	No	0	6	4
868	B:B:L318	B:B:V327	2.98	No	No	0	6	6
869	R:R:L432	R:R:V383	2.98	No	No	0	7	8
870	R:R:L433	R:R:V383	2.98	No	No	0	4	8
871	R:R:L391	R:R:V387	2.98	No	No	0	4	6
872	R:R:L307	R:R:T310	2.95	No	No	0	9	8
873	A:A:I245	A:A:I375	2.94	No	No	0	7	9
874	B:B:I157	B:B:I171	2.94	No	No	0	7	6
875	R:R:I211	R:R:I212	2.94	No	No	0	3	5
876	A:A:I383	A:A:M386	2.92	Yes	No	0	8	3
877	B:B:N132	B:B:T128	2.92	No	No	0	3	3
878	R:R:I489	R:R:M486	2.92	No	No	0	5	7
879	B:B:I37	B:B:K301	2.91	Yes	Yes	0	2	5
880	B:B:G64	B:B:Y105	2.9	No	No	0	5	6
881	R:R:G491	R:R:Y241	2.9	No	Yes	0	9	8
882	A:A:K34	A:A:M35	2.88	Yes	No	0	9	8
883	A:A:Q384	R:R:V400	2.87	No	Yes	0	6	8
884	B:B:Q259	G:G:V30	2.87	Yes	No	0	6	8
885	A:A:L30	B:B:I80	2.85	No	Yes	0	9	8
886	G:G:E58	G:G:V54	2.85	No	No	0	5	6
887	R:R:I454	R:R:L180	2.85	No	No	0	3	4
888	R:R:I209	R:R:L488	2.85	Yes	No	0	5	8
889	R:R:I226	R:R:L222	2.85	No	No	0	7	6
890	R:R:I436	R:R:L376	2.85	No	No	0	6	6
891	R:R:I436	R:R:L379	2.85	No	No	0	6	7
892	R:R:I489	R:R:L485	2.85	No	No	0	5	7
893	B:B:Q176	B:B:T179	2.83	Yes	No	0	4	4
894	R:R:L250	R:R:M247	2.83	No	No	0	4	5
895	B:B:E130	B:B:T128	2.82	No	No	0	3	3
896	R:R:K327	R:R:L330	2.82	No	No	0	6	6
897	A:A:K20	B:B:N88	2.8	No	No	0	5	7
898	B:B:D118	B:B:I120	2.8	No	No	0	9	6
899	R:R:C458	R:R:R459	2.79	No	No	35	9	4
900	R:R:C465	R:R:R459	2.79	No	No	35	9	4
901	A:A:D27	B:B:K89	2.77	No	Yes	0	7	9
902	A:A:A372	A:A:F212	2.77	No	Yes	0	8	9
903	B:B:D20	B:B:K23	2.77	No	No	0	2	2
904	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
905	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
906	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
907	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
908	G:G:A56	G:G:R62	2.77	No	No	0	4	7
909	R:R:H181	R:R:V182	2.77	No	No	0	4	5
910	R:R:D412	R:R:K413	2.77	No	No	0	4	9
911	B:B:E138	B:B:I120	2.73	No	No	0	6	6
912	B:B:N237	B:B:N239	2.72	No	No	0	5	2
913	A:A:K34	A:A:Q31	2.71	Yes	No	0	9	5
914	B:B:D66	B:B:L69	2.71	No	No	0	8	5
915	A:A:E392	R:R:K413	2.7	No	No	0	6	9
916	R:R:P464	R:R:W164	2.7	No	No	0	5	4
917	R:R:E442	R:R:K483	2.7	No	Yes	0	9	8
918	A:A:Y37	B:B:A56	2.67	Yes	No	0	9	7
919	B:B:A302	B:B:Y264	2.67	No	Yes	0	2	5
920	A:A:E33	B:B:L55	2.65	No	Yes	0	9	6
921	A:A:H387	A:A:I383	2.65	No	Yes	0	8	8
922	A:A:R356	A:A:T284	2.59	Yes	No	23	2	4
923	A:A:R389	A:A:T284	2.59	No	No	23	4	4
924	B:B:R49	B:B:T87	2.59	No	No	0	7	5
925	R:R:F231	R:R:T223	2.59	No	No	0	9	9
926	R:R:A315	R:R:W311	2.59	No	Yes	0	8	9
927	R:R:S200	R:R:Y204	2.54	No	No	0	3	4
928	B:B:I123	B:B:R137	2.51	No	No	0	6	5
929	R:R:F256	R:R:I206	2.51	No	No	0	6	7
930	R:R:F374	R:R:I345	2.51	No	No	0	8	4
931	R:R:F221	R:R:L218	2.44	Yes	No	0	7	4
932	R:R:F374	R:R:L342	2.44	No	No	0	8	7
933	B:B:F292	B:B:N313	2.42	No	No	0	4	7
934	A:A:D354	A:A:R356	2.38	No	Yes	0	3	2
935	A:A:E314	A:A:R317	2.33	No	No	0	6	2
936	R:R:E197	R:R:F201	2.33	No	No	0	4	6
937	R:R:K327	R:R:W319	2.32	No	No	0	6	8
938	A:A:R280	A:A:R283	2.13	No	No	0	5	3
939	A:A:G206	A:A:G226	2.11	No	No	0	8	9
940	A:A:G225	A:A:G226	2.11	No	No	0	9	9
941	B:B:G115	B:B:G116	2.11	No	No	0	9	9
942	B:B:G324	G:G:P49	2.03	No	No	0	9	7
943	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
944	B:B:C271	B:B:G272	1.96	Yes	No	0	5	4
945	B:B:C317	B:B:G330	1.96	No	No	0	7	5
946	R:R:C286	R:R:G354	1.96	No	No	3	9	8
947	R:R:C361	R:R:G354	1.96	No	No	3	9	8
948	A:A:A303	A:A:G304	1.95	No	No	0	5	5
949	B:B:A140	B:B:G141	1.95	No	No	0	5	5
950	B:B:A309	B:B:G310	1.95	No	No	0	3	5
951	R:R:C465	R:R:P466	1.88	No	No	0	9	5
952	B:B:A106	B:B:P107	1.87	No	No	0	6	6
953	B:B:A193	B:B:P194	1.87	No	No	0	4	4
954	R:R:A377	R:R:P378	1.87	No	No	0	4	9
955	R:R:G422	R:R:S425	1.86	No	No	0	7	8
956	B:B:G41	B:B:V40	1.84	No	No	0	1	3
957	B:B:G244	B:B:V276	1.84	No	No	0	5	6
958	B:B:G306	B:B:V296	1.84	No	Yes	0	4	5
959	R:R:G255	R:R:V360	1.84	No	No	0	8	7
960	R:R:G499	R:R:V498	1.84	No	No	0	7	7
961	B:B:G185	B:B:T164	1.82	No	No	0	5	6
962	B:B:G182	B:B:T181	1.82	No	No	0	6	2
963	B:B:G224	B:B:T223	1.82	No	No	0	6	2
964	R:R:G354	R:R:T278	1.82	No	Yes	0	8	6
965	A:A:A366	A:A:C365	1.81	No	No	0	9	8
966	R:R:G176	R:R:I171	1.76	No	No	0	2	4
967	R:R:G207	R:R:I206	1.76	No	No	0	6	7
968	A:A:G36	A:A:M35	1.75	No	No	0	4	8
969	A:A:P326	A:A:T325	1.75	No	No	0	1	2
970	A:A:P332	A:A:T335	1.75	No	No	0	1	4
971	B:B:P107	B:B:T65	1.75	No	No	0	6	1
972	G:G:P53	G:G:T52	1.75	No	No	0	8	4
973	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
974	B:B:G324	B:B:K280	1.74	No	No	0	9	1
975	R:R:C264	R:R:S275	1.72	No	No	0	9	3
976	B:B:C233	B:B:V276	1.71	No	No	0	3	6
977	R:R:A216	R:R:S215	1.71	No	No	0	8	3
978	A:A:G52	A:A:N292	1.7	No	No	0	9	9
979	A:A:G206	B:B:N119	1.7	No	No	0	8	9
980	A:A:A298	A:A:V334	1.7	No	Yes	0	4	4
981	A:A:A337	A:A:V301	1.7	No	No	0	8	7
982	B:B:A305	B:B:V296	1.7	No	Yes	0	4	5
983	R:R:A216	R:R:V495	1.7	No	Yes	0	8	8
984	R:R:A263	R:R:V262	1.7	No	No	0	7	6
985	R:R:A285	R:R:V262	1.7	No	No	0	5	6
986	R:R:A487	R:R:V435	1.7	No	No	0	5	7
987	A:A:A366	A:A:T55	1.68	No	No	0	9	9
988	G:G:A10	G:G:T6	1.68	No	No	0	2	3
989	R:R:A263	R:R:T278	1.68	No	Yes	0	7	6
990	B:B:K301	B:B:P39	1.67	Yes	No	0	5	1
991	A:A:E327	A:A:G329	1.64	No	No	22	4	7
992	A:A:E330	A:A:G329	1.64	Yes	No	22	3	7
993	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
994	R:R:L199	R:R:P190	1.64	No	No	0	6	3
995	R:R:C458	R:R:I463	1.64	No	No	0	9	5
996	B:B:A248	B:B:I269	1.62	No	No	0	5	4
997	R:R:A202	R:R:I357	1.62	No	Yes	0	7	8
998	G:G:A35	G:G:M38	1.61	No	No	0	2	4
999	R:R:A348	R:R:M349	1.61	No	No	0	7	4
1000	A:A:S54	A:A:T55	1.6	No	No	0	9	9
1001	B:B:S207	B:B:T223	1.6	Yes	No	0	5	2
1002	R:R:V384	R:R:V385	1.6	No	No	0	3	4
1003	R:R:V495	R:R:V498	1.6	Yes	No	0	8	7
1004	B:B:A11	G:G:L15	1.58	No	No	0	5	2
1005	B:B:A299	B:B:L300	1.58	No	Yes	0	5	6
1006	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
1007	A:A:C39	A:A:N218	1.57	No	No	0	9	4
1008	B:B:T165	B:B:T181	1.57	Yes	No	0	7	2
1009	B:B:T179	B:B:T181	1.57	No	No	0	4	2
1010	G:G:A56	G:G:N59	1.56	No	No	0	4	9
1011	R:R:C264	R:R:D260	1.56	No	No	0	9	6
1012	R:R:I426	R:R:V430	1.54	No	No	0	5	5
1013	B:B:M262	B:B:S31	1.53	No	No	0	4	1
1014	R:R:K318	R:R:V400	1.52	No	Yes	0	8	8
1015	R:R:I448	R:R:T452	1.52	No	No	0	3	5
1016	A:A:A298	A:A:E299	1.51	No	No	0	4	6
1017	G:G:A39	G:G:E42	1.51	No	No	0	3	1
1018	R:R:F440	R:R:G437	1.51	No	No	0	4	5
1019	R:R:K284	R:R:T287	1.5	No	Yes	0	6	7
1020	A:A:L388	R:R:V400	1.49	No	Yes	0	8	8
1021	A:A:D11	A:A:S7	1.47	No	No	0	2	6
1022	B:B:L152	B:B:T196	1.47	No	No	0	3	1
1023	R:R:I209	R:R:I212	1.47	Yes	No	0	5	5
1024	R:R:L342	R:R:T341	1.47	No	No	0	7	4
1025	R:R:I394	R:R:I395	1.47	No	No	0	7	5
1026	B:B:I37	G:G:M38	1.46	Yes	No	0	2	4
1027	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1028	G:G:A43	G:G:H44	1.46	No	No	0	4	6
1029	R:R:N265	R:R:T278	1.46	No	Yes	0	4	6
1030	B:B:D322	B:B:T65	1.45	No	No	0	1	1
1031	R:R:D227	R:R:T229	1.45	No	No	0	8	4
1032	B:B:M217	G:G:K20	1.44	Yes	No	0	3	6
1033	G:G:Q11	G:G:S8	1.44	Yes	No	0	3	4
1034	R:R:P475	R:R:R474	1.44	Yes	No	0	8	4
1035	R:R:I254	R:R:L289	1.43	No	No	0	4	7
1036	G:G:Q11	G:G:T6	1.42	Yes	No	0	3	3
1037	R:R:Q455	R:R:T451	1.42	No	No	0	3	3
1038	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
1039	R:R:P378	R:R:Y382	1.39	No	Yes	0	9	5
1040	A:A:L394	R:R:L414	1.38	No	No	0	8	9
1041	A:A:K216	A:A:Q213	1.36	No	No	0	4	3
1042	A:A:D295	A:A:L296	1.36	No	No	0	9	6
1043	B:B:E12	B:B:K15	1.35	No	No	0	4	6
1044	G:G:E47	G:G:K46	1.35	No	No	0	3	1
1045	R:R:E407	R:R:K408	1.35	No	No	0	6	7
1046	B:B:N35	B:B:Q32	1.32	No	No	0	1	1
1047	R:R:F219	R:R:V495	1.31	No	Yes	0	7	8
1048	A:A:D229	A:A:E230	1.3	No	Yes	0	8	9
1049	A:A:R13	A:A:T9	1.29	No	No	0	9	6
1050	B:B:E10	B:B:Q13	1.27	No	No	0	8	1
1051	A:A:Q390	A:A:R389	1.17	No	No	0	4	4
1052	B:B:R8	G:G:Q11	1.17	No	Yes	0	3	3
1053	B:B:Q44	B:B:R42	1.17	No	No	0	4	2
1054	B:B:E138	B:B:R96	1.16	No	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:K34	5.155	4	0	9
2	A:A:Y37	5.0175	4	1	9
3	A:A:R42	6.02	4	1	9
4	A:A:N50	6.38	4	17	9
5	A:A:F212	5.868	5	0	9
6	A:A:F219	7.19167	6	8	8
7	A:A:H220	5.766	5	1	7
8	A:A:F222	10.42	4	1	7
9	A:A:Q227	6.74	4	0	9
10	A:A:E230	7.73	4	1	9
11	A:A:K233	5.636	5	1	9
12	A:A:W234	5.356	5	15	9
13	A:A:F238	8.94	5	15	9
14	A:A:Y253	6.826	5	21	8
15	A:A:R265	10.09	4	17	9
16	A:A:F273	5.53833	6	4	9
17	A:A:W277	11.1025	4	4	6
18	A:A:W281	14.965	4	1	5
19	A:A:F290	5.0175	4	18	9
20	A:A:F315	11.89	4	0	6
21	A:A:P321	4.4075	4	12	5
22	A:A:E330	4.492	5	22	3
23	A:A:V334	4.8425	4	0	4
24	A:A:Y339	7.4325	4	4	3
25	A:A:F340	8.8025	4	12	7
26	A:A:R342	6.7325	4	4	4
27	A:A:E344	5.57	5	12	5
28	A:A:F345	8.215	4	4	8
29	A:A:L346	4.8125	4	4	4
30	A:A:R356	4.925	4	23	2
31	A:A:Y360	9.6025	4	24	8
32	A:A:F363	7.84	5	4	5
33	A:A:F376	7.87667	6	8	8
34	A:A:I383	4.14	4	8	8
35	B:B:L7	7.7	4	25	8
36	B:B:T34	3.73	4	0	5
37	B:B:I37	3.084	5	0	2
38	B:B:H54	7.78	6	11	9
39	B:B:L55	5.6075	4	0	6
40	B:B:K57	9	4	1	9
41	B:B:Y59	8.17667	6	1	8
42	B:B:M61	4.9275	4	5	6
43	B:B:W63	8.796	5	5	7
44	B:B:S72	4.9075	4	11	9
45	B:B:Q75	8.9225	4	1	9
46	B:B:I80	8.3475	4	11	8
47	B:B:W82	8.985	6	11	9
48	B:B:Y85	7.7675	4	5	4
49	B:B:K89	4.794	5	11	9
50	B:B:H91	5.8225	4	0	5
51	B:B:L95	3.9925	4	16	8
52	B:B:W99	10.8	4	0	9
53	B:B:M101	4.78	4	1	9
54	B:B:N110	6.79	4	28	4
55	B:B:C114	4.9825	4	16	8
56	B:B:Y124	5.435	6	16	6
57	B:B:H142	8.198	5	9	9
58	B:B:Y145	5.26667	6	1	8
59	B:B:F151	4.368	5	0	9
60	B:B:T159	5.542	5	9	9
61	B:B:T165	5.8725	4	9	7
62	B:B:W169	10.464	5	9	8
63	B:B:Q176	6.1925	4	9	4
64	B:B:F180	7.4325	4	6	7
65	B:B:H183	8.91833	6	6	9
66	B:B:D186	5.005	4	1	9
67	B:B:V187	4.638	5	6	9
68	B:B:L190	4.5575	4	0	5
69	B:B:F199	6.87	4	6	9
70	B:B:S201	4.915	4	6	9
71	B:B:C204	5.122	5	1	7
72	B:B:S207	5.485	4	6	5
73	B:B:K209	9.494	5	6	6
74	B:B:L210	5.388	5	2	5
75	B:B:W211	8.19833	6	6	8
76	B:B:M217	5.9375	4	2	3
77	B:B:R219	6.6575	4	2	5
78	B:B:Q220	7.485	4	2	7
79	B:B:H225	8.91714	7	2	9
80	B:B:I232	5.4775	4	0	8
81	B:B:F235	7.06833	6	19	6
82	B:B:F241	6.90833	6	2	6
83	B:B:T243	6.2775	4	2	8
84	B:B:D247	10.488	5	2	9
85	B:B:T249	8.4075	4	2	6
86	B:B:R251	8.968	5	2	8
87	B:B:F253	7.866	5	2	6
88	B:B:Q259	4.37	4	0	6
89	B:B:Y264	5.39667	6	0	5
90	B:B:C271	4.22	4	1	5
91	B:B:Y289	7.19	7	1	7
92	B:B:D290	8.625	4	1	6
93	B:B:D291	5.54	4	1	8
94	B:B:C294	4.085	4	7	5
95	B:B:N295	7.585	4	1	6
96	B:B:V296	3.1425	4	0	5
97	B:B:L300	3.81	4	0	6
98	B:B:K301	5.295	4	30	5
99	B:B:R304	4.5	4	1	5
100	B:B:H311	7.81	5	7	9
101	B:B:R314	14.218	5	1	8
102	B:B:T329	6.55	5	7	8
103	B:B:W332	9.735	6	1	9
104	B:B:D333	8.01	4	7	9
105	B:B:K337	7.6625	4	7	6
106	B:B:W339	8.25167	6	7	9
107	G:G:Q11	5.066	5	0	3
108	G:G:E22	5.32	4	26	9
109	G:G:Y40	12.74	4	19	6
110	G:G:D48	7.695	4	13	9
111	G:G:L51	5.314	5	13	6
112	G:G:F61	5.38833	6	5	8
113	R:R:Y177	12.7175	4	0	6
114	R:R:P187	8.3425	4	0	5
115	R:R:I209	4.475	4	0	5
116	R:R:T217	6.3475	4	10	8
117	R:R:F221	4.5325	4	0	7
118	R:R:Y233	7.005	6	0	9
119	R:R:F240	9.8475	4	14	8
120	R:R:Y241	6.444	5	10	8
121	R:R:T278	2.3375	4	0	6
122	R:R:Q279	9.7425	4	0	7
123	R:R:T287	2.6875	4	3	7
124	R:R:F290	6.672	5	3	9
125	R:R:Y294	8.0275	4	3	9
126	R:R:F295	6.838	5	0	8
127	R:R:W303	11.0167	6	14	9
128	R:R:W311	4.095	4	0	9
129	R:R:P339	4.3725	4	0	9
130	R:R:L346	9.1125	4	3	7
131	R:R:I352	5.384	5	3	8
132	R:R:D355	5.916	5	20	9
133	R:R:N356	5.76	4	20	6
134	R:R:I357	5.44	4	20	8
135	R:R:V363	5.4025	4	3	9
136	R:R:G364	4.2775	4	3	8
137	R:R:D367	5.7925	4	3	6
138	R:R:L371	4.9825	4	3	8
139	R:R:Y382	4.4625	4	0	5
140	R:R:V400	2.2375	4	0	8
141	R:R:I404	5.04	4	34	7
142	R:R:Q411	10.08	5	34	7
143	R:R:M418	4.86	4	0	8
144	R:R:Y428	11.075	4	10	8
145	R:R:Y439	4.594	5	3	5
146	R:R:W449	10.035	4	0	9
147	R:R:P475	7.915	4	0	8
148	R:R:K483	5.2775	4	0	8
149	R:R:P493	5.888	5	10	8
150	R:R:S494	4.56	5	10	8
151	R:R:V495	1.945	4	0	8
152	R:R:W497	9.03833	6	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:Y85	G:G:P60	16.6899	9.74	Yes	No	0	4	9
2	B:B:M325	G:G:P60	17.228	6.71	No	No	0	5	9
3	B:B:M325	G:G:P49	23.1491	3.35	No	No	0	5	7
4	G:G:D48	G:G:P49	24.7629	6.44	Yes	No	0	9	7
5	G:G:D48	G:G:L51	26.3765	8.14	Yes	Yes	13	9	6
6	B:B:R283	G:G:L51	30.141	9.72	No	Yes	0	9	6
7	B:B:I37	B:B:R283	15.3412	3.76	Yes	No	0	2	9
8	B:B:I37	B:B:T34	17.7579	3.04	Yes	Yes	0	2	5
9	B:B:L30	B:B:T34	34.4368	4.42	No	Yes	0	5	5
10	B:B:L30	B:B:M262	34.9725	4.24	No	No	0	5	4
11	B:B:M262	B:B:Y264	36.3114	8.38	No	Yes	0	4	5
12	B:B:W297	B:B:Y264	44.8602	6.75	No	Yes	0	8	5
13	B:B:W297	B:B:Y289	45.1195	6.75	No	Yes	1	8	7
14	B:B:C271	B:B:Y289	49.1345	4.03	Yes	Yes	1	5	7
15	B:B:C271	B:B:D290	51.2789	3.11	Yes	Yes	1	5	6
16	B:B:D290	B:B:R314	51.4802	16.68	Yes	Yes	1	6	8
17	B:B:R314	B:B:W332	61.6648	22.99	Yes	Yes	1	8	9
18	B:B:K57	B:B:W332	15.2996	12.76	Yes	Yes	1	9	9
19	B:B:L300	B:B:R283	15.338	6.07	Yes	No	0	6	9
20	B:B:L300	B:B:T34	16.1436	4.42	Yes	Yes	0	6	5
21	B:B:K57	B:B:Q75	15.3265	6.78	Yes	Yes	1	9	9
22	B:B:W332	B:B:Y59	47.4273	8.68	Yes	Yes	1	9	8
23	B:B:Q75	B:B:Y59	15.3278	18.04	Yes	Yes	1	9	8
24	A:A:F290	A:A:I56	99.263	3.77	Yes	No	0	9	7
25	A:A:I56	A:A:V247	99.3063	3.07	No	No	0	7	7
26	A:A:N292	A:A:V247	99.6082	4.43	No	No	0	9	7
27	A:A:K293	A:A:N292	99.6943	5.6	No	No	0	9	9
28	A:A:D249	A:A:K293	49.8692	15.21	No	No	0	8	9
29	A:A:D249	A:A:S251	49.8318	5.89	No	No	0	8	9
30	A:A:K300	A:A:S251	99.8067	4.59	No	No	0	9	9
31	A:A:K300	A:A:Y253	99.7731	9.55	No	Yes	21	9	8
32	A:A:I308	A:A:Y253	100	6.04	No	Yes	0	7	8
33	A:A:F315	A:A:I308	99.9977	15.07	Yes	No	0	6	7
34	A:A:F315	A:A:F340	99.5579	12.86	Yes	Yes	0	6	7
35	A:A:E344	A:A:F340	99.5919	3.5	Yes	Yes	12	5	7
36	A:A:E344	A:A:L270	99.6613	5.3	Yes	No	0	5	6
37	A:A:F345	A:A:L270	99.6514	9.74	Yes	No	0	8	6
38	A:A:F345	A:A:V248	49.6007	7.87	Yes	No	0	8	7
39	A:A:F246	A:A:V248	49.5648	3.93	No	No	0	9	7
40	A:A:F246	A:A:L272	99.4206	7.31	No	No	0	9	8
41	A:A:L272	A:A:R231	99.3203	8.5	No	No	0	8	9
42	A:A:R231	A:A:W234	99.077	9	No	Yes	15	9	9
43	A:A:Q227	A:A:W234	62.5784	6.57	Yes	Yes	0	9	9
44	A:A:Q227	B:B:L117	16.7672	5.32	Yes	No	0	9	9
45	A:A:C237	B:B:L117	16.3077	3.17	No	No	0	8	9
46	A:A:C237	B:B:Y59	16.2412	5.38	No	Yes	1	8	8
47	A:A:K293	A:A:L296	49.8692	5.64	No	No	0	9	6
48	A:A:L296	A:A:S251	49.9781	4.5	No	No	0	6	9
49	A:A:F273	A:A:F345	49.8888	4.29	Yes	Yes	4	9	8
50	A:A:F246	A:A:F273	49.9064	5.36	No	Yes	0	9	9
51	A:A:Q227	B:B:Y145	17.9591	4.51	Yes	Yes	0	9	8
52	B:B:M101	B:B:Y145	16.5071	7.18	Yes	Yes	1	9	8
53	B:B:M101	B:B:Y59	16.3092	3.59	Yes	Yes	1	9	8
54	A:A:F238	A:A:W234	36.417	4.01	Yes	Yes	15	9	9
55	A:A:F238	B:B:W99	36.1085	12.03	Yes	Yes	0	9	9
56	B:B:Q75	B:B:W99	33.419	6.57	Yes	Yes	0	9	9
57	A:A:Q227	B:B:N119	32.9455	10.56	Yes	No	0	9	9
58	A:A:D378	A:A:H362	97.2815	13.87	No	No	0	7	9
59	A:A:H362	A:A:R374	97.3921	10.16	No	No	0	9	4
60	A:A:E370	A:A:R374	97.5027	15.12	No	No	0	4	4
61	A:A:D368	A:A:E370	97.6133	12.99	No	No	0	9	4
62	A:A:D368	A:A:T364	48.8619	4.34	No	No	18	9	9
63	A:A:F290	A:A:T364	48.9134	6.49	Yes	No	18	9	9
64	A:A:D368	A:A:N371	48.8619	13.46	No	No	18	9	9
65	A:A:F290	A:A:N371	48.9134	6.04	Yes	No	18	9	9
66	A:A:D378	A:A:Y360	96.9495	11.49	No	Yes	0	7	8
67	A:A:R385	A:A:Y358	96.3959	6.17	No	No	0	5	4
68	A:A:R385	A:A:Y360	96.4992	9.26	No	Yes	24	5	8
69	A:A:Y358	R:R:K408	95.62	5.97	No	No	0	4	7
70	R:R:E409	R:R:K408	95.3982	21.6	No	No	0	6	7
71	R:R:E409	R:R:I404	95.2873	5.47	No	Yes	0	6	7
72	R:R:I404	R:R:Q411	94.6138	8.23	Yes	Yes	34	7	7
73	R:R:L414	R:R:Q411	93.287	7.99	No	Yes	0	9	7
74	A:A:L393	R:R:L414	92.619	4.15	No	No	0	8	9
75	A:A:L393	R:R:F417	92.5076	17.05	No	No	0	8	8
76	R:R:F417	R:R:W497	91.7272	3.01	No	Yes	0	8	9
77	R:R:I238	R:R:W497	47.1253	3.52	No	Yes	0	9	9
78	R:R:I238	R:R:S494	47.0104	3.1	No	Yes	0	9	8
79	R:R:S494	R:R:Y241	42.3979	5.09	Yes	Yes	10	8	8
80	R:R:Y241	R:R:Y245	84.2324	5.96	Yes	No	0	8	8
81	R:R:G300	R:R:Y245	83.763	4.35	No	No	0	8	8
82	R:R:C244	R:R:G300	83.5283	3.92	No	No	0	9	8
83	R:R:C244	R:R:F296	83.0588	4.19	No	No	0	9	8
84	R:R:F295	R:R:F296	82.3543	8.57	Yes	No	0	8	8
85	R:R:F295	R:R:W336	24.0283	5.01	Yes	No	0	8	9
86	R:R:W303	R:R:W336	15.1384	14.06	Yes	No	14	9	9
87	R:R:F240	R:R:R236	11.0569	6.41	Yes	No	0	8	9
88	R:R:R236	R:R:Y233	10.5764	10.29	No	Yes	0	9	9
89	R:R:I324	R:R:Y233	12.2591	7.25	No	Yes	0	9	9
90	R:R:F424	R:R:W497	44.1578	11.02	No	Yes	0	9	9
91	R:R:F424	R:R:P493	43.8119	7.22	No	Yes	0	9	8
92	R:R:P493	R:R:Y241	42.2794	8.34	Yes	Yes	10	8	8
93	B:B:G144	B:B:N119	32.6829	3.39	No	No	0	8	9
94	B:B:G144	B:B:T143	32.6172	3.64	No	No	0	8	5
95	B:B:D163	B:B:T143	32.5515	10.12	No	No	0	9	5
96	B:B:D163	B:B:S161	16.0328	7.36	No	No	9	9	9
97	B:B:H142	B:B:S161	15.9649	16.74	Yes	No	9	9	9
98	B:B:H142	B:B:T159	30.6755	5.48	Yes	Yes	9	9	9
99	B:B:C149	B:B:T159	27.6408	5.07	No	Yes	0	8	9
100	B:B:C149	B:B:T102	27.5022	3.38	No	No	0	8	8
101	B:B:C148	B:B:T102	27.2252	3.38	No	No	0	6	8
102	B:B:C148	B:B:L190	26.5413	3.17	No	Yes	0	6	5
103	B:B:F199	B:B:L190	24.5815	6.09	Yes	Yes	0	9	5
104	B:B:F180	B:B:F199	22.4776	7.5	Yes	Yes	6	7	9
105	B:B:F180	B:B:T178	22.233	5.19	Yes	No	0	7	4
106	B:B:T177	B:B:T178	22.0938	4.71	No	No	0	4	4
107	B:B:L168	B:B:T177	21.9545	4.42	No	No	0	6	4
108	B:B:L168	B:B:V213	20.7	2.98	No	No	0	6	4
109	B:B:R214	B:B:V213	20.5606	5.23	No	No	0	9	4
110	B:B:E215	B:B:R214	19.7234	3.49	No	No	0	3	9
111	B:B:Q220	B:B:R219	13.2454	4.67	Yes	Yes	2	7	5
112	B:B:D163	B:B:T165	16.4529	13.01	No	Yes	9	9	7
113	B:B:H142	B:B:T165	15.9691	4.11	Yes	Yes	9	9	7
114	R:R:F295	R:R:P339	57.8322	7.22	Yes	Yes	0	8	9
115	R:R:M298	R:R:P339	53.072	3.35	No	Yes	0	7	9
116	R:R:M298	R:R:Y294	51.1685	10.78	No	Yes	0	7	9
117	R:R:F362	R:R:Y294	28.0029	7.22	No	Yes	0	7	9
118	R:R:F362	R:R:L365	20.3813	3.65	No	No	0	7	6
119	R:R:D355	R:R:L365	20.1421	4.07	Yes	No	0	9	6
120	R:R:D355	R:R:N356	17.2847	4.04	Yes	Yes	20	9	6
121	R:R:M192	R:R:N356	12.9834	7.01	No	Yes	0	7	6
122	R:R:F290	R:R:Y294	14.3688	8.25	Yes	Yes	3	9	9
123	R:R:G364	R:R:V363	21.542	3.68	Yes	Yes	3	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8JHI

PDB Summary
PDB	8JHI
Class	F
SubFamily	Protein
Type	Frizzled
SubType	FZD3
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	chim(NtGsXLas-Gs)/Beta1/Gamma2
PDB Resolution	3.2
Date	2024-01-17
D.O.I.	10.1038/s41421-023-00627-y

Net Summary
I_min	3.01
Number of Linked Nodes	904
Number of Links	1054
Number of Hubs	152
Number of Links mediated by Hubs	558
Number of Communities	35
Number of Nodes involved in Communities	242
Number of Links involved in Communities	325

Path Summary
Number Of Nodes in MetaPath	124
Number Of Links MetaPath	123
Number of Shortest Paths	11712461
Length Of Smallest Path	3
Average Path Length	63.0841
Length of Longest Path	95
Minimum Path Strength	1.295
Average Path Strength	7.88578
Maximum Path Strength	20.99
Minimum Path Correlation	0.7
Average Path Correlation	0.998065
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.78571
Average % Of Corr. Nodes	28.3699
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.2976
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • mu-type opioid receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • opioid receptor binding • beta-2 adrenergic receptor binding • adrenergic receptor binding • ionotropic glutamate receptor binding • glutamate receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • peptide hormone receptor binding • corticotropin-releasing hormone receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • D1 dopamine receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • cation binding • metal ion binding • insulin-like growth factor receptor binding • developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • animal organ development • bone development • system development • regulation of body fluid levels • wound healing • response to stimulus • homotypic cell-cell adhesion • cell activation • hemostasis
Gene Ontology	Biological Process	• developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • animal organ development • bone development • system development • regulation of body fluid levels • wound healing • response to stimulus • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • cellular process • regulation of biological quality • response to wounding • platelet activation • developmental growth • growth • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • cellular response to catecholamine stimulus • serotonin receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-activating serotonin receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to hormone • response to endogenous stimulus • response to alcohol • response to prostaglandin E • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • apical part of cell • plasma membrane region • apical plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • transmembrane signaling receptor activity • signaling receptor activity • Wnt receptor activity • G protein-coupled receptor activity • PDZ domain binding • protein domain specific binding • Wnt-protein binding • response to xenobiotic stimulus • cell surface receptor signaling pathway • canonical Wnt signaling pathway • Wnt signaling pathway • head development • brain development • nervous system development • central nervous system development • cell proliferation in midbrain • midbrain development • neural precursor cell proliferation • ear morphogenesis • embryonic organ morphogenesis • ear development • embryonic morphogenesis • embryo development • anatomical structure morphogenesis • sensory organ morphogenesis • inner ear development • inner ear morphogenesis • animal organ morphogenesis • embryonic organ development • non-canonical Wnt signaling pathway • epithelium development • epidermis development • molting cycle process • hair cycle • tissue development • skin development • skin epidermis development • hair follicle development • molting cycle • hair cycle process • sympathetic nervous system development • ganglion development • autonomic nervous system development • sympathetic ganglion development • cellular developmental process • generation of neurons • neurogenesis • neuron differentiation • cell differentiation • neuron migration • motor neuron migration • cell migration • cell motility • regulation of mitotic cell cycle, embryonic • negative regulation of biological process • negative regulation of cell cycle • mitotic cell cycle • negative regulation of mitotic cell cycle • mitotic cell cycle, embryonic • regulation of mitotic cell cycle • negative regulation of cellular process • negative regulation of mitotic cell cycle, embryonic • cell cycle • regulation of cell cycle • commissural neuron axon guidance • axonogenesis • cell projection organization • plasma membrane bounded cell projection morphogenesis • cell development • neuron projection development • cell morphogenesis • cellular component organization • cell projection morphogenesis • neuron projection morphogenesis • cellular component organization or biogenesis • plasma membrane bounded cell projection organization • axon guidance • axon development • cell morphogenesis involved in neuron differentiation • neuron projection guidance • neuron development • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of execution phase of apoptosis • regulation of programmed cell death • cell death • regulation of execution phase of apoptosis • execution phase of apoptosis • negative regulation of apoptotic process • apoptotic process • programmed cell death • post-anal tail morphogenesis • response to electrical stimulus • response to abiotic stimulus • embryonic epithelial tube formation • chordate embryonic development • tube formation • epithelial tube formation • tube morphogenesis • primary neural tube formation • embryo development ending in birth or egg hatching • epithelial tube morphogenesis • morphogenesis of embryonic epithelium • neural tube development • tube development • morphogenesis of an epithelium • tissue morphogenesis • neural tube closure • neural tube formation • anatomical structure formation involved in morphogenesis • tube closure • Wnt signaling pathway, planar cell polarity pathway • dopaminergic neuron axon guidance • serotonergic neuron axon guidance • brain morphogenesis • midbrain morphogenesis • neuroblast proliferation • positive regulation of nervous system development • positive regulation of cell population proliferation • regulation of developmental process • positive regulation of biological process • regulation of neuroblast proliferation • regulation of cell differentiation • regulation of neurogenesis • regulation of cell development • regulation of nervous system development • positive regulation of developmental process • positive regulation of cell differentiation • positive regulation of neurogenesis • regulation of multicellular organismal process • positive regulation of cellular process • regulation of neural precursor cell proliferation • regulation of multicellular organismal development • positive regulation of cell development • positive regulation of neural precursor cell proliferation • regulation of cell population proliferation • positive regulation of multicellular organismal process • positive regulation of neuroblast proliferation • establishment of planar polarity • establishment of tissue polarity • morphogenesis of a polarized epithelium • cell surface • filopodium tip • actin-based cell projection • filopodium • somatodendritic compartment • dendrite • dendritic tree • glutamatergic synapse • presynaptic active zone membrane • presynaptic membrane • synaptic membrane • presynapse • presynaptic active zone • cell body • neuronal cell body • axon • lateral plasma membrane
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8JHI_Chain_A N S K T E D K R A Q K R A E K K R S K L I D K Q L Q D E K M G Y M C T H R L L L L G A D N S G K S T I V K Q M R G I F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8JHI_Chain_B L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8JHI_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q9NPG1
Sequence	>8JHI_Chain_R W C P R E L K I D G Y S F L H V R D C S P P C P N M Y F R R E E L S F A R Y F I G L I S I I C L S A T L F T F L T F L I D V T R F R Y P E R P I I F Y A V C Y M M V S L I F F I G F L L E D R V A C N S T V T Q G S H N K A C T M L F M I L Y F F T M A G S V W W V I L T I T W F L A A V P K W G S E A I E K K A L L F H A S A W G I P G T L T I I L L A M N K I E G D N I S G V C F V G L Y D V D A L R Y F V L A P L C L Y V V V G V S L L L G I I S L N R V R I E I P L E K E N Q D K L V K F M I R I G V F S I L Y L V P L L V V I G C Y F Y E Q A Y R G I W E T T W I Q E R C R E Y H I P C P M S R P D L I L F L M K Y L M A L I V G I P S V F W V G S K K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8QW4	F	Protein	Frizzled	FZD₃	Homo sapiens	-	-	-	2.9	2024-09-04	doi.org/10.1038/s41467-024-51451-1
	8JHC	F	Protein	Frizzled	FZD₃	Homo sapiens	-	-	-	3.3	2024-01-17	10.1038/s41421-023-00627-y
	8JHI (No Gprot)	F	Protein	Frizzled	FZD₃	Homo sapiens	-	-		3.2	2024-01-17	10.1038/s41421-023-00627-y

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