psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y22	9.77	Yes	Yes	1	0	6
2	L:L:?1	R:R:Y26	4.19	Yes	Yes	1	0	8
3	L:L:?1	R:R:R75	7.23	Yes	Yes	1	0	6
4	L:L:?1	R:R:Y79	6.28	Yes	Yes	1	0	5
5	L:L:?1	R:R:F95	6.52	Yes	Yes	1	0	5
6	L:L:?1	R:R:Y99	14.65	Yes	Yes	1	0	4
7	L:L:?1	R:R:Y103	9.07	Yes	No	1	0	7
8	L:L:?1	R:R:L151	4.12	Yes	No	1	0	8
9	L:L:?1	R:R:F152	18.85	Yes	No	1	0	3
10	L:L:?1	R:R:L155	4.12	Yes	No	1	0	4
11	L:L:?1	R:R:R156	11.57	Yes	Yes	1	0	5
12	L:L:?1	R:R:V170	5.32	Yes	Yes	1	0	5
13	L:L:?1	R:R:F250	10.15	Yes	Yes	1	0	5
14	L:L:?1	R:R:D253	6.46	Yes	No	1	0	4
15	L:L:?1	R:R:K257	6.71	Yes	No	1	0	5
16	L:L:?1	R:R:H274	6.89	Yes	Yes	1	0	5
17	L:L:?1	R:R:L278	7.41	Yes	Yes	1	0	5
18	R:R:T15	R:R:Y19	21.22	No	Yes	1	4	5
19	R:R:T15	R:R:V170	6.35	No	Yes	1	4	5
20	R:R:D171	R:R:T15	7.23	Yes	No	1	4	4
21	R:R:D16	R:R:F17	14.33	No	No	0	4	4
22	R:R:R18	R:R:V170	6.54	No	Yes	0	4	5
23	R:R:L271	R:R:R18	14.58	No	No	0	3	4
24	R:R:R18	R:R:S275	6.59	No	No	0	4	4
25	R:R:Y19	R:R:Y79	14.89	Yes	Yes	1	5	5
26	R:R:H82	R:R:Y19	9.8	No	Yes	0	4	5
27	R:R:V170	R:R:Y19	5.05	Yes	Yes	1	5	5
28	R:R:D171	R:R:Y19	8.05	Yes	Yes	1	4	5
29	R:R:F20	R:R:V24	6.55	No	No	0	4	5
30	R:R:Y22	R:R:Y26	6.95	Yes	Yes	1	6	8
31	R:R:Y22	R:R:Y79	11.91	Yes	Yes	1	6	5
32	R:R:S275	R:R:Y22	11.45	No	Yes	0	4	6
33	R:R:C279	R:R:T25	10.14	No	No	0	5	4
34	R:R:L72	R:R:Y26	11.72	No	Yes	0	8	8
35	R:R:R75	R:R:Y26	4.12	Yes	Yes	1	6	8
36	R:R:S282	R:R:Y26	7.63	No	Yes	0	6	8
37	R:R:I76	R:R:T27	4.56	No	No	0	7	5
38	R:R:I29	R:R:L283	4.28	Yes	No	0	7	5
39	R:R:C286	R:R:I29	6.55	No	Yes	0	7	7
40	R:R:L30	R:R:L34	6.92	No	No	0	6	6
41	R:R:L30	R:R:P73	6.57	No	No	0	6	9
42	R:R:G33	R:R:V69	5.52	No	No	0	8	5
43	R:R:L34	R:R:V69	4.47	No	No	0	6	5
44	R:R:D65	R:R:N37	6.73	Yes	No	0	9	9
45	R:R:L66	R:R:N37	5.49	No	No	0	7	9
46	R:R:N37	R:R:P289	8.15	No	No	0	9	9
47	R:R:F294	R:R:L39	6.09	No	No	0	7	6
48	R:R:L41	R:R:Y45	11.72	No	Yes	0	6	3
49	R:R:F299	R:R:V43	18.35	Yes	No	0	8	7
50	R:R:R302	R:R:V43	5.23	Yes	No	0	5	7
51	R:R:F44	R:R:V55	6.55	No	No	0	6	7
52	R:R:F44	R:R:I59	6.28	No	No	0	6	5
53	R:R:F44	R:R:Y293	10.32	No	Yes	0	6	7
54	R:R:T51	R:R:Y47	12.48	No	Yes	2	6	5
55	R:R:R53	R:R:Y47	11.32	No	Yes	2	6	5
56	R:R:E298	R:R:Y47	7.86	No	Yes	2	6	5
57	R:R:R302	R:R:Y47	6.17	Yes	Yes	2	5	5
58	R:R:E50	R:R:R302	11.63	No	Yes	0	6	5
59	R:R:R53	R:R:T51	10.35	No	No	2	6	6
60	R:R:C111	R:R:F57	12.57	No	Yes	0	6	7
61	R:R:F57	R:R:R115	6.41	Yes	No	4	7	8
62	R:R:D134	R:R:F57	7.17	No	Yes	4	8	7
63	R:R:F57	R:R:I137	6.28	Yes	No	0	7	5
64	R:R:I112	R:R:M58	4.37	No	No	0	8	8
65	R:R:M58	R:R:Y293	11.97	No	Yes	0	8	7
66	R:R:F108	R:R:N60	15.71	No	No	6	7	9
67	R:R:N60	R:R:S138	8.94	No	No	0	9	5
68	R:R:N60	R:R:W142	5.65	No	Yes	6	9	9
69	R:R:D65	R:R:L61	4.07	Yes	No	0	9	9
70	R:R:L109	R:R:L61	5.54	Yes	No	0	8	9
71	R:R:L61	R:R:Y293	5.86	No	Yes	0	9	7
72	R:R:D65	R:R:S105	4.42	Yes	No	0	9	9
73	R:R:D65	R:R:S285	5.89	Yes	No	0	9	8
74	R:R:D288	R:R:D65	10.65	No	Yes	0	9	9
75	R:R:L67	R:R:N101	4.12	No	No	0	7	8
76	R:R:K98	R:R:Q68	6.78	Yes	Yes	0	6	7
77	R:R:N101	R:R:Q68	9.24	No	Yes	0	8	7
78	R:R:M102	R:R:Q68	6.8	No	Yes	0	7	7
79	R:R:Q68	R:R:S285	12.99	Yes	No	0	7	8
80	R:R:R75	R:R:S71	5.27	Yes	No	1	6	7
81	R:R:K98	R:R:S71	6.12	Yes	No	1	6	7
82	R:R:L74	R:R:W84	5.69	No	Yes	0	6	8
83	R:R:C94	R:R:L74	4.76	No	No	0	4	6
84	R:R:K98	R:R:R75	19.8	Yes	Yes	1	6	6
85	R:R:F169	R:R:R75	23.52	Yes	Yes	1	4	6
86	R:R:F77	R:R:N81	10.87	No	No	0	4	3
87	R:R:F77	R:R:F86	9.65	No	Yes	0	4	6
88	R:R:Y78	R:R:Y79	5.96	Yes	Yes	1	5	5
89	R:R:W84	R:R:Y78	4.82	Yes	Yes	1	8	5
90	R:R:C168	R:R:Y78	8.06	Yes	Yes	1	9	5
91	R:R:F169	R:R:Y78	4.13	Yes	Yes	1	4	5
92	R:R:D171	R:R:Y78	6.9	Yes	Yes	1	4	5
93	R:R:V170	R:R:Y79	8.83	Yes	Yes	1	5	5
94	R:R:D83	R:R:P85	6.44	No	No	0	4	3
95	R:R:F86	R:R:W84	15.03	Yes	Yes	0	6	8
96	R:R:C91	R:R:W84	11.75	No	Yes	1	9	8
97	R:R:C168	R:R:W84	18.28	Yes	Yes	1	9	8
98	R:R:F86	R:R:P85	8.67	Yes	No	0	6	3
99	R:R:G87	R:R:P88	4.06	No	No	0	7	3
100	R:R:C168	R:R:C91	7.28	Yes	No	1	9	9
101	R:R:M92	R:R:P153	6.71	No	No	0	7	4
102	R:R:F93	R:R:L97	12.18	No	No	0	5	5
103	R:R:F95	R:R:Y99	10.32	Yes	Yes	1	5	4
104	R:R:F95	R:R:R156	6.41	Yes	Yes	1	5	5
105	R:R:F169	R:R:F95	4.29	Yes	Yes	1	4	5
106	R:R:V100	R:R:Y96	17.66	No	Yes	0	4	5
107	R:R:C146	R:R:Y96	5.38	No	Yes	0	4	5
108	R:R:P153	R:R:Y96	5.56	No	Yes	0	4	5
109	R:R:K98	R:R:Y99	9.55	Yes	Yes	1	6	4
110	R:R:K98	R:R:L278	4.23	Yes	Yes	1	6	5
111	R:R:F152	R:R:Y99	13.41	No	Yes	1	3	4
112	R:R:Y246	R:R:Y99	5.96	Yes	Yes	1	6	4
113	R:R:C149	R:R:V100	6.83	No	No	0	7	4
114	R:R:M102	R:R:Y246	4.79	No	Yes	0	7	6
115	R:R:Y103	R:R:Y246	4.96	No	Yes	1	7	6
116	R:R:H247	R:R:Y103	7.62	Yes	No	1	8	7
117	R:R:A104	R:R:W142	7.78	No	Yes	0	7	9
118	R:R:F243	R:R:I106	15.07	No	No	0	9	7
119	R:R:F108	R:R:Y107	9.28	No	Yes	0	7	5
120	R:R:C111	R:R:Y107	6.72	No	Yes	0	6	5
121	R:R:G141	R:R:Y107	7.24	No	Yes	0	7	5
122	R:R:F108	R:R:W142	11.02	No	Yes	6	7	9
123	R:R:F239	R:R:L109	4.87	No	Yes	0	9	8
124	R:R:D288	R:R:L109	9.5	No	Yes	0	9	8
125	R:R:L109	R:R:Y292	8.21	Yes	Yes	0	8	9
126	R:R:I200	R:R:V110	4.61	No	No	0	7	7
127	R:R:I112	R:R:R116	5.01	No	Yes	5	8	9
128	R:R:I112	R:R:Y292	4.84	No	Yes	5	8	9
129	R:R:S113	R:R:V201	6.46	No	No	0	9	8
130	R:R:C204	R:R:S113	5.16	No	No	0	6	9
131	R:R:F126	R:R:R115	4.28	Yes	No	0	5	8
132	R:R:D134	R:R:R115	5.96	No	No	4	8	8
133	R:R:F119	R:R:R116	5.34	No	Yes	0	8	9
134	R:R:I232	R:R:R116	5.01	No	Yes	0	7	9
135	R:R:R116	R:R:Y292	7.2	Yes	Yes	5	9	9
136	R:R:F117	R:R:M121	4.98	Yes	No	3	8	7
137	R:R:F117	R:R:Y122	6.19	Yes	Yes	3	8	7
138	R:R:C204	R:R:F117	9.78	No	Yes	0	6	8
139	R:R:F117	R:R:K207	4.96	Yes	No	0	8	4
140	R:R:W118	R:R:Y122	4.82	No	Yes	3	5	7
141	R:R:R125	R:R:W118	4	No	No	3	5	5
142	R:R:F126	R:R:W118	6.01	Yes	No	0	5	5
143	R:R:F119	R:R:L120	6.09	No	No	0	8	8
144	R:R:F119	R:R:F126	11.79	No	Yes	0	8	5
145	R:R:L120	R:R:T208	4.42	No	No	0	8	8
146	R:R:L120	R:R:L212	4.15	No	Yes	0	8	8
147	R:R:M121	R:R:Y122	10.78	No	Yes	3	7	7
148	R:R:R125	R:R:Y122	8.23	No	Yes	3	5	7
149	R:R:H127	R:R:K130	9.17	No	No	0	5	7
150	R:R:D128	R:R:Q131	14.36	No	No	0	5	3
151	R:R:I139	R:R:L135	5.71	No	No	0	2	3
152	R:R:I139	R:R:L143	4.28	No	No	0	2	4
153	R:R:C149	R:R:F152	4.19	No	No	0	7	3
154	R:R:L151	R:R:L155	8.3	No	No	1	8	4
155	R:R:L151	R:R:M185	8.48	No	No	1	8	4
156	R:R:L154	R:R:R175	8.5	No	No	0	4	4
157	R:R:L155	R:R:M185	5.65	No	No	1	4	4
158	R:R:L172	R:R:R156	7.29	No	Yes	0	4	5
159	R:R:K257	R:R:R156	11.14	No	Yes	1	5	5
160	R:R:R175	R:R:T157	6.47	No	No	0	4	4
161	R:R:K167	R:R:L172	4.23	No	No	0	4	4
162	R:R:C168	R:R:F169	9.78	Yes	Yes	1	9	4
163	R:R:D171	R:R:V170	5.84	Yes	Yes	1	4	5
164	R:R:N178	R:R:V177	5.91	No	No	0	1	2
165	R:R:N178	R:R:Q181	17.17	No	No	0	1	4
166	R:R:E260	R:R:L179	6.63	No	No	0	3	3
167	R:R:M186	R:R:P251	5.03	No	No	0	4	6
168	R:R:F254	R:R:M186	4.98	No	No	0	4	4
169	R:R:E190	R:R:H247	12.31	No	Yes	1	5	8
170	R:R:E190	R:R:F250	8.16	No	Yes	1	5	5
171	R:R:E190	R:R:P251	11	No	No	1	5	6
172	R:R:G193	R:R:I192	5.29	No	No	0	5	4
173	R:R:G193	R:R:P197	4.06	No	Yes	0	5	9
174	R:R:F194	R:R:L198	10.96	No	No	0	8	6
175	R:R:F194	R:R:H247	28.28	No	Yes	0	8	8
176	R:R:P197	R:R:T196	5.25	Yes	No	0	9	5
177	R:R:L198	R:R:L240	4.15	No	No	0	6	5
178	R:R:K207	R:R:Y203	16.72	No	No	0	4	3
179	R:R:I232	R:R:T205	4.56	No	No	0	7	9
180	R:R:A236	R:R:T205	5.03	No	No	0	7	9
181	R:R:K207	R:R:W206	6.96	No	No	0	4	3
182	R:R:L210	R:R:W206	10.25	No	No	0	4	3
183	R:R:I232	R:R:T208	4.56	No	No	0	7	8
184	R:R:L229	R:R:V209	5.96	Yes	No	0	5	5
185	R:R:L212	R:R:L229	4.15	Yes	Yes	0	8	5
186	R:R:L229	R:R:Q213	3.99	Yes	No	0	5	4
187	R:R:D214	R:R:M218	8.32	No	No	0	5	2
188	R:R:D214	R:R:K225	12.44	No	No	0	5	6
189	R:R:M218	R:R:Y216	8.38	No	No	0	2	4
190	R:R:D221	R:R:E224	5.2	No	No	0	5	5
191	R:R:D221	R:R:K225	4.15	No	No	0	5	6
192	R:R:L229	R:R:Q226	3.99	Yes	No	0	5	4
193	R:R:K230	R:R:Q226	4.07	No	No	0	6	4
194	R:R:K227	R:R:M231	4.32	No	Yes	0	7	7
195	R:R:C235	R:R:Y292	12.1	No	Yes	0	7	9
196	R:R:I291	R:R:V238	6.14	No	No	0	7	6
197	R:R:F239	R:R:F243	9.65	No	No	0	9	9
198	R:R:C242	R:R:N284	12.6	No	Yes	0	7	9
199	R:R:F243	R:R:N284	10.87	No	Yes	0	9	9
200	R:R:H247	R:R:Y246	14.16	Yes	Yes	1	8	6
201	R:R:F250	R:R:Y246	6.19	Yes	Yes	1	5	6
202	R:R:L278	R:R:Y246	4.69	Yes	Yes	1	5	6
203	R:R:H274	R:R:S249	8.37	Yes	No	0	5	4
204	R:R:F250	R:R:P251	5.78	Yes	No	1	5	6
205	R:R:I270	R:R:L252	7.14	No	No	0	4	4
206	R:R:D253	R:R:K257	13.83	No	No	1	4	5
207	R:R:D253	R:R:H274	26.47	No	Yes	1	4	5
208	R:R:I261	R:R:L255	4.28	No	No	0	1	4
209	R:R:I261	R:R:V256	4.61	No	Yes	0	1	2
210	R:R:R267	R:R:V256	10.46	No	Yes	0	3	2
211	R:R:I270	R:R:V256	6.14	No	Yes	0	4	2
212	R:R:N259	R:R:R267	7.23	No	No	0	1	3
213	R:R:L265	R:R:R268	8.5	No	No	0	2	2
214	R:R:H274	R:R:L278	7.71	Yes	Yes	1	5	5
215	R:R:D288	R:R:N284	9.42	No	Yes	0	9	9
216	R:R:F299	R:R:Y293	8.25	Yes	Yes	0	8	7
217	R:R:N297	R:R:R300	8.44	No	No	0	6	8
218	R:R:E298	R:R:R301	9.3	No	No	0	6	5
219	R:R:E298	R:R:R302	8.14	No	Yes	2	6	5
220	R:R:E260	R:R:L255	3.98	No	No	0	3	4
221	R:R:F254	R:R:S182	3.96	No	No	0	4	4
222	R:R:F273	R:R:S249	3.96	No	No	0	5	4
223	R:R:R268	R:R:V269	3.92	No	No	0	2	3
224	R:R:R156	R:R:T174	3.88	Yes	No	0	5	3
225	R:R:F17	R:R:I272	3.77	No	No	0	4	1
226	L:L:?1	R:R:A148	3.75	Yes	No	0	0	4
227	R:R:M231	R:R:R116	3.72	Yes	Yes	0	7	9
228	R:R:F86	R:R:L90	3.65	Yes	No	0	6	5
229	R:R:I145	R:R:Y107	3.63	No	Yes	0	8	5
230	R:R:K132	R:R:Y133	3.58	No	No	0	4	4
231	R:R:P32	R:R:V31	3.53	No	No	0	5	5
232	R:R:G36	R:R:I35	3.53	No	No	0	8	4
233	R:R:P197	R:R:V110	3.53	Yes	No	0	9	7
234	R:R:G189	R:R:I188	3.53	No	No	0	5	4
235	R:R:C204	R:R:V114	3.42	No	No	0	6	6
236	R:R:A277	R:R:S249	3.42	No	No	0	6	4
237	R:R:A266	R:R:S263	3.42	No	No	0	1	6
238	R:R:I106	R:R:P197	3.39	No	Yes	0	7	9
239	R:R:D221	R:R:G223	3.35	No	No	0	5	3
240	R:R:A54	R:R:I56	3.25	No	No	0	7	6
241	R:R:S182	R:R:V177	3.23	No	No	0	4	2
242	R:R:F294	R:R:F299	3.22	No	Yes	0	7	8
243	R:R:A62	R:R:L41	3.15	No	No	0	8	6
244	R:R:I29	R:R:S282	3.1	Yes	No	0	7	6
245	R:R:I56	R:R:S138	3.1	No	No	0	6	5
246	R:R:F93	R:R:Y96	3.09	No	Yes	0	5	5
247	R:R:I35	R:R:V31	3.07	No	No	0	4	5
248	R:R:I188	R:R:V184	3.07	No	No	0	4	2
249	R:R:M231	R:R:S295	3.07	Yes	No	0	7	6
250	R:R:I29	R:R:T25	3.04	Yes	No	0	7	4
251	R:R:I291	R:R:T234	3.04	No	No	0	7	5
252	R:R:F294	R:R:G36	3.01	No	No	0	7	8
253	R:R:L135	R:R:S138	3	No	No	0	3	5
254	R:R:L212	R:R:S211	3	Yes	No	0	8	4
255	R:R:L191	R:R:V195	2.98	No	No	0	4	4
256	R:R:L199	R:R:V195	2.98	No	No	0	3	4
257	R:R:L233	R:R:V209	2.98	No	No	0	5	5
258	R:R:L271	R:R:V256	2.98	No	Yes	0	3	2
259	R:R:N284	R:R:V238	2.96	Yes	No	0	9	6
260	R:R:L191	R:R:T187	2.95	No	No	0	4	4
261	R:R:I59	R:R:I63	2.94	No	No	0	5	5
262	R:R:W42	R:R:Y45	2.89	No	Yes	0	3	3
263	R:R:I76	R:R:L30	2.85	No	No	0	7	6
264	R:R:I63	R:R:L41	2.85	No	No	0	5	6
265	R:R:K225	R:R:L212	2.82	No	Yes	0	6	8
266	R:R:G87	R:R:W84	2.81	No	Yes	0	7	8
267	R:R:L34	R:R:L70	2.77	No	No	0	6	5
268	R:R:A40	R:R:F299	2.77	No	Yes	0	9	8
269	R:R:L66	R:R:L70	2.77	No	No	0	7	5
270	R:R:L198	R:R:L202	2.77	No	No	0	6	3
271	R:R:L283	R:R:L287	2.77	No	No	0	5	6
272	R:R:A64	R:R:W142	2.59	No	Yes	0	8	9
273	R:R:F126	R:R:K130	2.48	Yes	No	0	5	7
274	R:R:F299	R:R:L303	2.44	Yes	No	0	8	6
275	R:R:L135	R:R:Y136	2.34	No	No	0	3	1
276	R:R:G89	R:R:P88	2.03	No	No	0	3	3
277	R:R:A140	R:R:G141	1.95	No	No	0	3	7
278	R:R:A236	R:R:G237	1.95	No	No	0	7	4
279	R:R:A244	R:R:P245	1.87	No	No	0	5	9
280	R:R:A277	R:R:P245	1.87	No	No	0	6	9
281	R:R:G189	R:R:I192	1.76	No	No	0	5	4
282	R:R:C279	R:R:I21	1.64	No	No	0	5	5
283	R:R:L172	R:R:P173	1.64	No	No	0	4	5
284	R:R:L280	R:R:P245	1.64	No	No	0	7	9
285	R:R:C129	R:R:K130	1.62	No	No	0	3	7
286	R:R:S182	R:R:V183	1.62	No	No	0	4	3
287	R:R:A266	R:R:I261	1.62	No	No	0	1	1
288	R:R:A281	R:R:M102	1.61	No	No	0	8	7
289	R:R:A228	R:R:M231	1.61	No	Yes	0	7	7
290	R:R:S258	R:R:T174	1.6	No	No	0	2	3
291	R:R:S295	R:R:T296	1.6	No	No	0	6	8
292	R:R:T25	R:R:V24	1.59	No	No	0	4	5
293	R:R:T187	R:R:V183	1.59	No	No	0	4	3
294	R:R:A23	R:R:L80	1.58	No	No	0	5	4
295	R:R:I270	R:R:V269	1.54	No	No	0	4	3
296	R:R:M48	R:R:V55	1.52	No	No	0	5	7
297	R:R:L147	R:R:V150	1.49	No	No	0	4	4
298	R:R:L154	R:R:V150	1.49	No	No	0	4	4
299	R:R:I21	R:R:I272	1.47	No	No	0	5	1
300	R:R:G46	R:R:Y45	1.45	No	Yes	0	4	3
301	R:R:I38	R:R:L66	1.43	No	No	0	3	7
302	R:R:I76	R:R:L80	1.43	No	No	0	7	4
303	R:R:P123	R:R:Y122	1.39	No	Yes	0	8	7
304	R:R:P217	R:R:Y216	1.39	No	No	0	3	4
305	R:R:E224	R:R:L222	1.33	No	No	0	5	4
306	R:R:D134	R:R:Q131	1.31	No	No	0	8	3
307	R:R:I137	R:R:Y133	1.21	No	No	0	5	4
308	R:R:N176	R:R:R175	1.21	No	No	0	4	4
309	R:R:N297	R:R:R301	1.21	No	No	0	6	5
310	R:R:K49	R:R:Y45	1.19	No	Yes	0	6	3
311	R:R:K215	R:R:Y216	1.19	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	7.94778	18	1	0
2	R:R:Y19	11.802	5	1	5
3	R:R:Y22	10.02	4	1	6
4	R:R:Y26	6.922	5	1	8
5	R:R:I29	4.2425	4	0	7
6	R:R:Y45	4.3125	4	0	3
7	R:R:Y47	9.4575	4	2	5
8	R:R:F57	8.1075	4	4	7
9	R:R:D65	6.352	5	0	9
10	R:R:Q68	8.9525	4	0	7
11	R:R:R75	11.988	5	1	6
12	R:R:Y78	5.974	5	1	5
13	R:R:Y79	9.574	5	1	5
14	R:R:W84	9.73	6	1	8
15	R:R:F86	9.25	4	0	6
16	R:R:F95	6.885	4	1	5
17	R:R:Y96	7.9225	4	0	5
18	R:R:K98	9.296	5	1	6
19	R:R:Y99	10.778	5	1	4
20	R:R:Y107	6.7175	4	0	5
21	R:R:L109	7.03	4	0	8
22	R:R:R116	5.256	5	5	9
23	R:R:F117	6.4775	4	3	8
24	R:R:Y122	6.282	5	3	7
25	R:R:F126	6.14	4	0	5
26	R:R:W142	6.76	4	6	9
27	R:R:R156	8.058	5	1	5
28	R:R:C168	10.85	4	1	9
29	R:R:F169	10.43	4	1	4
30	R:R:V170	6.32167	6	1	5
31	R:R:D171	7.005	4	1	4
32	R:R:P197	4.0575	4	0	9
33	R:R:L212	3.53	4	0	8
34	R:R:L229	4.5225	4	0	5
35	R:R:M231	3.18	4	0	7
36	R:R:Y246	6.79167	6	1	6
37	R:R:H247	15.5925	4	1	8
38	R:R:F250	7.57	4	1	5
39	R:R:V256	6.0475	4	0	2
40	R:R:H274	12.36	4	1	5
41	R:R:L278	6.01	4	1	5
42	R:R:N284	8.9625	4	0	9
43	R:R:Y292	8.0875	4	5	9
44	R:R:Y293	9.1	4	0	7
45	R:R:F299	7.006	5	0	8
46	R:R:R302	7.7925	4	2	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:V170	32.5378	5.32	Yes	Yes	1	0	5
2	R:R:S282	R:R:Y26	10.5093	7.63	No	Yes	0	6	8
3	L:L:?1	R:R:R75	18.7868	7.23	Yes	Yes	1	0	6
4	R:R:K98	R:R:R75	40.2574	19.8	Yes	Yes	1	6	6
5	R:R:K98	R:R:Q68	88.947	6.78	Yes	Yes	0	6	7
6	R:R:Q68	R:R:S285	99.9939	12.99	Yes	No	0	7	8
7	R:R:D65	R:R:S285	100	5.89	Yes	No	0	9	8
8	R:R:D65	R:R:N37	12.2646	6.73	Yes	No	0	9	9
9	R:R:L66	R:R:N37	10.5459	5.49	No	No	0	7	9
10	L:L:?1	R:R:Y99	18.6829	14.65	Yes	Yes	1	0	4
11	R:R:K98	R:R:Y99	26.0604	9.55	Yes	Yes	1	6	4
12	L:L:?1	R:R:L278	18.6951	7.41	Yes	Yes	1	0	5
13	R:R:K98	R:R:L278	22.3157	4.23	Yes	Yes	1	6	5
14	R:R:D65	R:R:L61	54.1265	4.07	Yes	No	0	9	9
15	R:R:L61	R:R:Y293	17.4795	5.86	No	Yes	0	9	7
16	R:R:F299	R:R:Y293	13.6614	8.25	Yes	Yes	0	8	7
17	R:R:L109	R:R:L61	39.1252	5.54	Yes	No	0	8	9
18	R:R:L109	R:R:Y292	76.487	8.21	Yes	Yes	0	8	9
19	R:R:R116	R:R:Y292	73.5609	7.2	Yes	Yes	5	9	9
20	R:R:F119	R:R:R116	68.236	5.34	No	Yes	0	8	9
21	R:R:F119	R:R:F126	49.1417	11.79	No	Yes	0	8	5
22	R:R:F126	R:R:R115	29.3857	4.28	Yes	No	0	5	8
23	R:R:F57	R:R:R115	24.9099	6.41	Yes	No	4	7	8
24	R:R:C111	R:R:F57	20.4219	12.57	No	Yes	0	6	7
25	R:R:D288	R:R:D65	46.242	10.65	No	Yes	0	9	9
26	R:R:D288	R:R:L109	38.9358	9.5	No	Yes	0	9	8
27	R:R:C111	R:R:Y107	19.2531	6.72	No	Yes	0	6	5
28	R:R:F108	R:R:Y107	14.5371	9.28	No	Yes	0	7	5
29	R:R:M102	R:R:Y246	11.674	4.79	No	Yes	0	7	6
30	R:R:F169	R:R:R75	14.9952	23.52	Yes	Yes	1	4	6
31	R:R:F126	R:R:W118	16.9032	6.01	Yes	No	0	5	5
32	R:R:W118	R:R:Y122	14.5126	4.82	No	Yes	3	5	7
33	R:R:F117	R:R:Y122	10.9389	6.19	Yes	Yes	3	8	7
34	R:R:F119	R:R:L120	21.5765	6.09	No	No	0	8	8
35	R:R:R18	R:R:V170	26.1602	6.54	No	Yes	0	4	5
36	R:R:L271	R:R:R18	25.2235	14.58	No	No	0	3	4
37	R:R:L271	R:R:V256	23.7451	2.98	No	Yes	0	3	2
38	R:R:I261	R:R:V256	10.2731	4.61	No	Yes	0	1	2
39	R:R:L120	R:R:L212	20.5034	4.15	No	Yes	0	8	8
40	R:R:K225	R:R:L212	11.4908	2.82	No	Yes	0	6	8
41	R:R:M102	R:R:Q68	11.3767	6.8	No	Yes	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:Y22	9.77	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Y26	4.19	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:R75	7.23	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Y79	6.28	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F95	6.52	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y99	14.65	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:Y103	9.07	1	Yes	No	0	7	0	1
L:L:?1	R:R:L151	4.12	1	Yes	No	0	8	0	1
L:L:?1	R:R:F152	18.85	1	Yes	No	0	3	0	1
L:L:?1	R:R:L155	4.12	1	Yes	No	0	4	0	1
L:L:?1	R:R:R156	11.57	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:V170	5.32	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F250	10.15	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:D253	6.46	1	Yes	No	0	4	0	1
L:L:?1	R:R:K257	6.71	1	Yes	No	0	5	0	1
L:L:?1	R:R:H274	6.89	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L278	7.41	1	Yes	Yes	0	5	0	1
R:R:T15	R:R:Y19	21.22	1	No	Yes	4	5	2	2
R:R:T15	R:R:V170	6.35	1	No	Yes	4	5	2	1
R:R:D171	R:R:T15	7.23	1	Yes	No	4	4	2	2
R:R:R18	R:R:V170	6.54	0	No	Yes	4	5	2	1
R:R:R18	R:R:S275	6.59	0	No	No	4	4	2	2
R:R:Y19	R:R:Y79	14.89	1	Yes	Yes	5	5	2	1
R:R:V170	R:R:Y19	5.05	1	Yes	Yes	5	5	1	2
R:R:D171	R:R:Y19	8.05	1	Yes	Yes	4	5	2	2
R:R:Y22	R:R:Y26	6.95	1	Yes	Yes	6	8	1	1
R:R:Y22	R:R:Y79	11.91	1	Yes	Yes	6	5	1	1
R:R:S275	R:R:Y22	11.45	0	No	Yes	4	6	2	1
R:R:L72	R:R:Y26	11.72	0	No	Yes	8	8	2	1
R:R:R75	R:R:Y26	4.12	1	Yes	Yes	6	8	1	1
R:R:S282	R:R:Y26	7.63	0	No	Yes	6	8	2	1
R:R:R75	R:R:S71	5.27	1	Yes	No	6	7	1	2
R:R:K98	R:R:S71	6.12	1	Yes	No	6	7	2	2
R:R:K98	R:R:R75	19.8	1	Yes	Yes	6	6	2	1
R:R:F169	R:R:R75	23.52	1	Yes	Yes	4	6	2	1
R:R:Y78	R:R:Y79	5.96	1	Yes	Yes	5	5	2	1
R:R:F169	R:R:Y78	4.13	1	Yes	Yes	4	5	2	2
R:R:D171	R:R:Y78	6.9	1	Yes	Yes	4	5	2	2
R:R:V170	R:R:Y79	8.83	1	Yes	Yes	5	5	1	1
R:R:F95	R:R:Y99	10.32	1	Yes	Yes	5	4	1	1
R:R:F95	R:R:R156	6.41	1	Yes	Yes	5	5	1	1
R:R:F169	R:R:F95	4.29	1	Yes	Yes	4	5	2	1
R:R:K98	R:R:Y99	9.55	1	Yes	Yes	6	4	2	1
R:R:K98	R:R:L278	4.23	1	Yes	Yes	6	5	2	1
R:R:F152	R:R:Y99	13.41	1	No	Yes	3	4	1	1
R:R:Y246	R:R:Y99	5.96	1	Yes	Yes	6	4	2	1
R:R:Y103	R:R:Y246	4.96	1	No	Yes	7	6	1	2
R:R:H247	R:R:Y103	7.62	1	Yes	No	8	7	2	1
R:R:C149	R:R:F152	4.19	0	No	No	7	3	2	1
R:R:L151	R:R:L155	8.3	1	No	No	8	4	1	1
R:R:L151	R:R:M185	8.48	1	No	No	8	4	1	2
R:R:L155	R:R:M185	5.65	1	No	No	4	4	1	2
R:R:L172	R:R:R156	7.29	0	No	Yes	4	5	2	1
R:R:K257	R:R:R156	11.14	1	No	Yes	5	5	1	1
R:R:D171	R:R:V170	5.84	1	Yes	Yes	4	5	2	1
R:R:E190	R:R:H247	12.31	1	No	Yes	5	8	2	2
R:R:E190	R:R:F250	8.16	1	No	Yes	5	5	2	1
R:R:E190	R:R:P251	11	1	No	No	5	6	2	2
R:R:H247	R:R:Y246	14.16	1	Yes	Yes	8	6	2	2
R:R:F250	R:R:Y246	6.19	1	Yes	Yes	5	6	1	2
R:R:L278	R:R:Y246	4.69	1	Yes	Yes	5	6	1	2
R:R:H274	R:R:S249	8.37	1	Yes	No	5	4	1	2
R:R:F250	R:R:P251	5.78	1	Yes	No	5	6	1	2
R:R:D253	R:R:K257	13.83	1	No	No	4	5	1	1
R:R:D253	R:R:H274	26.47	1	No	Yes	4	5	1	1
R:R:H274	R:R:L278	7.71	1	Yes	Yes	5	5	1	1
R:R:R156	R:R:T174	3.88	1	Yes	No	5	3	1	2
L:L:?1	R:R:A148	3.75	1	Yes	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8KH5_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.99
Number of Linked Nodes	268
Number of Links	311
Number of Hubs	46
Number of Links mediated by Hubs	169
Number of Communities	6
Number of Nodes involved in Communities	52
Number of Links involved in Communities	85

Path Summary
Number Of Nodes in MetaPath	42
Number Of Links MetaPath	41
Number of Shortest Paths	70817
Length Of Smallest Path	3
Average Path Length	14.8514
Length of Longest Path	31
Minimum Path Strength	1.29
Average Path Strength	7.58664
Maximum Path Strength	21.66
Minimum Path Correlation	0.7
Average Path Correlation	0.924283
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	46.0264
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	52.6781
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multicellular organismal process • multicellular organismal-level homeostasis • leukocyte homeostasis • T cell homeostasis • homeostatic process • immune system process • homeostasis of number of cells • lymphocyte homeostasis • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell communication • negative regulation of biological process • negative regulation of interleukin-2 production • regulation of cytokine production • cytokine production • negative regulation of cellular process • regulation of multicellular organismal process • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • regulation of interleukin-2 production • negative regulation of metabolic process • interleukin-2 production • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • negative regulation of gene expression • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular organelle • intracellular anatomical structure • organelle • intracellular membrane-bounded organelle • intracellular membraneless organelle • centrosome • microtubule organizing center • cytoskeleton • centriolar satellite
Gene Ontology	Cellular Component	• cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular organelle • intracellular anatomical structure • organelle • intracellular membrane-bounded organelle • intracellular membraneless organelle • centrosome • microtubule organizing center • cytoskeleton • centriolar satellite • membraneless organelle • microtubule cytoskeleton • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network • organelle membrane • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	LPS
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	LPS
Name	Lysophosphotidylserine
Synonyms	LYSOPHOSPHOTIDYLSERINE
Identifier
Formula	C21 H44 N O9 P
Molecular Weight	485.549
SMILES
PubChem	17754066
Formal Charge	0
Total Atoms	76
Total Chiral Atoms	4
Total Bonds	75
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BXC1
Sequence	>8KH5_nogp_Chain_R T D F R Y F I Y A V T Y T V I L V P G L I G N I L A L W V F Y G Y M K E T K R A V I F M I N L A I A D L L Q V L S L P L R I F Y Y L N H D W P F G P G L C M F C F Y L K Y V N M Y A S I Y F L V C I S V R R F W F L M Y P F R F H D C K Q K Y D L Y I S I A G W L I I C L A C V L F P L L R T K C F V D L P T R N V N L A Q S V V M M T I G E L I G F V T P L L I V L Y C T W K T V L S L Q D K Y P M A Q D L G E K Q K A L K M I L T C A G V F L I C F A P Y H F S F P L D F L V K S N E I K S C L A R R V I L I F H S V A L C L A S L N S C L D P V I Y Y F S T N E F R R R L S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8IZB	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-	Gs/β1/γ2	3.06	2023-11-01	10.1371/journal.pbio.3002387
	8IZB (No Gprot)	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-		3.06	2023-11-01	10.1371/journal.pbio.3002387
	7XV3	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-	chim(NtGi1-Gs)/β1/γ2	2.76	2023-02-15	10.1038/s41467-023-36575-0
	7XV3 (No Gprot)	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-		2.76	2023-02-15	10.1038/s41467-023-36575-0
	8KH5	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-	Gs/β1/γ2	2.83	2023-10-11	10.1038/s41467-023-41654-3
	8KH5 (No Gprot)	A	Orphan	Orphan	GPR174	Homo sapiens	Lysophosphatidylserine	-		2.83	2023-10-11	10.1038/s41467-023-41654-3

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