Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1B:B:L7 5.3825198
2B:B:I18 3.725407
3B:B:T34 3.73405
4B:B:M45 3.7225434
5B:B:R48 2.9125477
6B:B:R52 7.1175437
7B:B:H54 8.60167699
8B:B:K57 12.4925419
9B:B:M61 4.0875406
10B:B:W63 5.50667607
11B:B:S72 6.07499
12B:B:Q75 5.74419
13B:B:D76 6.5275499
14B:B:K78 5.775408
15B:B:I80 7.7725498
16B:B:W82 8.22429799
17B:B:Y85 11.3525474
18B:B:K89 7.13286799
19B:B:H91 5.68254115
20B:B:I93 5.0754117
21B:B:L95 4.04254118
22B:B:W99 8.695429
23B:B:Y105 4.045406
24B:B:N110 6.2025424
25B:B:Y111 4.608524
26B:B:C114 3.3954118
27B:B:Y124 5.613336116
28B:B:H142 7.20667629
29B:B:Y145 5.59333628
30B:B:C148 3.79456
31B:B:C149 2.595428
32B:B:R150 6.6225456
33B:B:F151 4.89529
34B:B:L152 3.2875403
35B:B:T159 5.4425429
36B:B:S160 3.536556
37B:B:S161 7.805429
38B:B:D163 9.435429
39B:B:W169 7.76286728
40B:B:T173 3.6775405
41B:B:F180 6.23557
42B:B:H183 5.53333659
43B:B:L190 4.14455
44B:B:F199 6.078559
45B:B:V200 5.755416
46B:B:D205 5.9725459
47B:B:K209 6.12456
48B:B:L210 4.495405
49B:B:W211 8.04658
50B:B:F222 4.614518
51B:B:H225 8.525619
52B:B:D228 4.782529
53B:B:I232 5.006518
54B:B:F235 4.33875816
55B:B:P236 5.32417
56B:B:F241 4.28616
57B:B:T243 4.416518
58B:B:G244 2.554515
59B:B:D247 6.315419
60B:B:T249 6.715416
61B:B:C250 2.93167618
62B:B:R251 8.732518
63B:B:F253 5.3616
64B:B:D258 9.7625417
65B:B:Y264 5.346505
66B:B:C271 3.83415
67B:B:V276 2.8525416
68B:B:F278 4.512517
69B:B:R283 7.586209
70B:B:L285 4.218516
71B:B:Y289 4.81143717
72B:B:D290 7.5875416
73B:B:D291 5.4075418
74B:B:N293 5.22415
75B:B:N295 6.274516
76B:B:V296 2.375405
77B:B:W297 3.91857718
78B:B:L300 5.466506
79B:B:K301 5.51405
80B:B:L308 5.8425437
81B:B:H311 9.442539
82B:B:R314 8.615418
83B:B:L318 2.986166
84B:B:G319 2.0554165
85B:B:T321 5.7925477
86B:B:M325 4.205675
87B:B:V327 4.214166
88B:B:W332 8.69333619
89B:B:D333 5.038539
90B:B:F335 6.328534
91B:B:L336 4.412597
92B:B:K337 7.1436
93B:B:W339 6.12639
94G:G:R27 5.93418
95G:G:Y40 8.515416
96G:G:N59 5.22579
97G:G:P60 8.3575479
98G:G:F61 4.30111978
99R:R:L54 3.1675407
100R:R:F58 4.455407
101R:R:N61 5.4654139
102R:R:I71 3.9375436
103R:R:I82 5.265408
104R:R:D83 3.19254237
105R:R:L85 3.7325486
106R:R:I89 5.634139
107R:R:N92 5.86254138
108R:R:L96 6.974138
109R:R:F109 4.6425404
110R:R:I122 7.795466
111R:R:Y125 5.02566
112R:R:Y126 4.505665
113R:R:L127 4.4725465
114R:R:Y128 7.40754139
115R:R:Y130 4.5875408
116R:R:L131 6.3275407
117R:R:D132 7.464139
118R:R:V139 4.275488
119R:R:R143 6.442589
120R:R:Y144 5.9425408
121R:R:V147 3.51408
122R:R:W154 7.2125405
123R:R:W169 5.954569
124R:R:S176 3.9225467
125R:R:R183 8.72466
126R:R:D188 6.0025441
127R:R:P189 3.665442
128R:R:Y197 6.195444
129R:R:W207 8.0885184
130R:R:R208 5.865444
131R:R:R212 5.73667645
132R:R:F220 5.514259
133R:R:P223 2.7885149
134R:R:F230 6.0325408
135R:R:Y231 7.32167689
136R:R:W235 7.1675405
137R:R:L243 4.6225103
138R:R:F260 5.814149
139R:R:F263 5.4575408
140R:R:F265 8.5854255
141R:R:Y267 9.5575407
142R:R:H268 5.625409
143R:R:D274 7.6025445
144R:R:R278 4.58444
145R:R:L301 4.945405
146R:R:Y306 6.8054149
147R:R:V310 7.0325409
148R:R:Y314 4.47833689
149R:R:S315 5.245437
150R:R:F321 7.085438
151R:R:R324 12.2425435
152L:L:E6 5.61333640
153L:L:R8 6.11640
154L:L:H19 4.895210
155L:L:K29 4.32440
156L:L:P33 4.2575440
157L:L:I41 4.655440
158L:L:C51 5.12440
159L:L:N53 5.814150
160L:L:S56 5.2785150
161A:A:L5 3.4975402
162A:A:I19 3.2499
163A:A:R21 4.12754264
164A:A:L37 4.974529
165A:A:L39 3.78857729
166A:A:G183 2.1625409
167A:A:I184 2.884529
168A:A:F189 7.9775409
169A:A:F191 5.71754285
170A:A:F196 7.76407
171A:A:K197 7.4406
172A:A:M198 4.8275407
173A:A:F199 6.888525
174A:A:V201 4.062529
175A:A:R208 5.9725409
176A:A:K210 5.088529
177A:A:W211 3.48333629
178A:A:F215 6.24529
179A:A:I221 4.1425428
180A:A:F223 4.444509
181A:A:Y230 4.6485128
182A:A:M243 3.6425128
183A:A:L249 3.5925409
184A:A:F250 6.135629
185A:A:W258 4.4825415
186A:A:F259 5.01529
187A:A:I264 3.214526
188A:A:I265 3.11754108
189A:A:F267 4.637109
190A:A:L283 3.1785127
191A:A:C286 4.93754126
192A:A:Y287 5.066258127
193A:A:Y302 3.18754126
194A:A:I303 2.665407
195A:A:F307 3.724528
196A:A:L310 5.24404
197A:A:E318 6.9654104
198A:A:Y320 3.8656107
199A:A:T324 6.43754109
200A:A:D328 6.72254109
201A:A:N331 9.7754108
202A:A:F334 7.00754103
203A:A:F336 5.4454288
204A:A:G352 2.095408
205A:A:F354 5.79571785
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1B:B:G244 B:B:T243 38.47141.82YesYes158
2B:B:I43 B:B:M45 10.23482.92NoYes034
3B:B:C233 B:B:S277 16.16381.72NoNo035
4B:B:C233 B:B:F278 16.05322.79NoYes037
5B:B:F278 B:B:L285 15.13627.31YesYes176
6B:B:L318 B:B:T329 26.63954.42YesNo068
7B:B:H311 B:B:T329 34.22685.48YesNo098
8B:B:G319 B:B:W63 25.61352.81YesYes057
9B:B:G244 B:B:I273 27.44315.29YesNo156
10B:B:I273 B:B:Y289 27.89264.84NoYes167
11B:B:C271 B:B:Y289 34.87254.03YesYes157
12B:B:C271 B:B:D290 35.94123.11YesYes156
13B:B:D290 B:B:R314 36.26517.87YesYes168
14B:B:R314 B:B:W332 25.561111YesYes189
15B:B:N313 B:B:W332 64.1426.78NoYes079
16B:B:D333 B:B:N313 64.22932.69YesNo097
17B:B:L70 B:B:W82 10.17347.97NoYes059
18B:B:L70 B:B:W63 10.20096.83NoYes057
19A:A:H213 A:A:W258 20.11927.41NoYes085
20A:A:W258 B:B:R314 11.11013YesYes158
21B:B:C114 B:B:G115 10.48521.96YesNo089
22A:A:K210 B:B:Y145 19.09594.78YesYes298
23A:A:H213 A:A:K210 21.07312.62NoYes089
24B:B:G202 B:B:S201 12.79981.86NoNo069
25B:B:G202 B:B:S189 13.10353.71NoNo067
26B:B:I232 B:B:S189 13.40684.64YesNo087
27B:B:H142 B:B:S161 10.791615.34YesYes299
28B:B:G162 B:B:S161 13.19463.71NoYes299
29B:B:G162 B:B:Y145 13.48235.79NoYes298
30A:A:N256 A:A:W258 27.20085.65NoYes085
31A:A:F259 A:A:N256 26.75696.04YesNo098
32B:B:D312 B:B:D333 1005.32NoYes359
33B:B:D312 R:R:R324 99.55397.15NoYes355
34R:R:I71 R:R:R324 99.80222.51YesYes365
35R:R:F321 R:R:I71 99.75887.54YesYes386
36R:R:F321 R:R:V68 99.12792.62YesNo389
37R:R:C90 R:R:V68 99.92331.71NoNo089
38R:R:C90 R:R:N65 93.04464.72NoNo089
39R:R:N65 R:R:P311 72.45244.89NoNo099
40R:R:P311 R:R:V310 53.66615.3NoYes099
41R:R:V310 R:R:Y306 35.822210.09YesYes099
42R:R:F260 R:R:Y306 34.10946.19YesYes1499
43R:R:F260 R:R:L224 33.59223.65YesNo096
44R:R:F220 R:R:L224 33.42462.44YesNo096
45R:R:F220 R:R:H268 32.18565.66YesYes099
46R:R:H268 R:R:Y267 30.60654.36YesYes097
47R:R:N271 R:R:Y267 30.080218.61NoYes057
48R:R:N271 R:R:R212 26.61648.44NoYes055
49R:R:R208 R:R:R212 16.72183.2YesYes445
50R:R:R208 R:R:Y197 22.13775.14YesYes444
51R:R:D188 R:R:P189 17.90753.22YesYes412
52L:L:K29 R:R:P189 15.6083.35YesYes402
53L:L:I41 L:L:K29 14.46172.91YesYes400
54L:L:C51 L:L:I41 13.31436.55YesYes400
55L:L:C51 R:R:V38 12.17785.12YesNo004
56L:L:L7 R:R:Y197 10.938410.55NoYes004
57R:R:N61 R:R:N65 23.70946.81YesNo099
58R:R:L96 R:R:N61 12.94926.87YesYes1389
59R:R:F58 R:R:L96 14.54842.44YesYes078
60R:R:F58 R:R:L100 13.17464.87YesNo078
61R:R:L100 R:R:L54 12.91342.77NoYes087
62R:R:V310 R:R:Y314 36.41522.52YesYes099
63R:R:N92 R:R:Y128 10.7116.98YesYes1389
64R:R:L131 R:R:N92 18.88755.49YesYes078
65R:R:L131 R:R:W169 27.218413.67YesYes079
66R:R:I89 R:R:P311 19.145.08YesNo099
67R:R:L127 R:R:W169 32.01354.56YesYes659
68R:R:C95 R:R:L127 13.74313.17NoYes065
69R:R:C95 R:R:F124 13.19832.79NoNo064
70R:R:I122 R:R:Y126 17.00933.63YesYes665
71R:R:L127 R:R:S176 19.61976.01YesYes657
72R:R:S176 R:R:Y126 17.22542.54YesYes675
73R:R:I122 R:R:R183 16.413416.28YesYes666
74R:R:R143 R:R:Y314 29.09353.09YesYes899
75A:A:F354 R:R:R143 28.08516.03YesYes859
76A:A:F354 A:A:L348 25.62816.09YesNo059
77R:R:E198 R:R:R183 13.96311.63NoYes056
78A:A:I344 A:A:L348 25.48722.85NoNo069
79A:A:I344 R:R:T241 25.27013.04NoNo066
80R:R:L243 R:R:T241 12.59532.95YesNo036
81A:A:D341 R:R:T241 12.5097.23NoNo086
82A:A:Y320 R:R:L243 10.42852.34YesYes1073
83A:A:D341 A:A:Y320 10.439911.49NoYes087
84A:A:I221 A:A:I264 13.43214.42YesYes286
85A:A:F259 A:A:I221 16.33085.02YesYes298
86A:A:F334 A:A:Y320 16.15432.06YesYes1037
87A:A:F267 A:A:F334 11.89375.36YesYes1093
88A:A:F250 A:A:I264 10.64032.51YesYes296
89B:B:M45 B:B:W339 12.91663.49YesYes349
90B:B:I232 B:B:T243 19.28883.04YesYes188
91B:B:D333 B:B:H311 44.55835.04YesYes399
92B:B:G319 B:B:L318 16.56471.71YesYes1656
93A:A:W258 B:B:W332 36.13581.87YesYes159
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:H19 R:R:C30 2.95 21 Yes No 0 4 0 1
L:L:C22 R:R:C30 7.28 21 No No 0 4 0 1
L:L:H19 R:R:N31 3.83 21 Yes No 0 6 0 1
R:R:F32 R:R:S33 5.28 0 No No 3 6 1 2
L:L:I18 R:R:F32 15.07 0 No No 0 3 0 1
L:L:N46 R:R:L34 5.49 0 No No 0 2 0 1
L:L:R48 R:R:E35 13.96 0 No No 0 3 0 1
L:L:L15 R:R:V36 5.96 0 No No 0 3 0 1
R:R:E40 R:R:V38 4.28 0 No No 4 4 1 1
L:L:C51 R:R:V38 5.12 4 Yes No 0 4 0 1
R:R:C39 R:R:R289 4.18 0 No No 8 3 2 1
R:R:E40 R:R:M41 10.83 0 No No 4 2 1 2
L:L:K49 R:R:E40 6.75 0 No No 0 4 0 1
R:R:A297 R:R:V45 5.09 0 No No 5 4 1 2
R:R:L100 R:R:L54 2.77 0 No Yes 8 7 2 1
R:R:E103 R:R:L54 3.98 22 No Yes 6 7 2 1
R:R:L301 R:R:L54 2.77 0 Yes Yes 5 7 2 1
L:L:A1 R:R:L54 3.15 0 No Yes 0 7 0 1
R:R:A102 R:R:E121 3.02 0 No No 7 5 2 1
R:R:E121 R:R:I122 8.2 0 No Yes 5 6 1 1
L:L:S2 R:R:E121 5.75 0 No No 0 5 0 1
R:R:I122 R:R:Y126 3.63 6 Yes Yes 6 5 1 1
R:R:I122 R:R:R183 16.28 6 Yes Yes 6 6 1 2
L:L:V3 R:R:I122 3.07 6 No Yes 0 6 0 1
R:R:Y125 R:R:Y126 1.99 6 Yes Yes 6 5 1 1
R:R:V129 R:R:Y125 7.57 0 No Yes 7 6 2 1
R:R:S300 R:R:Y125 3.82 0 No Yes 7 6 1 1
L:L:A1 R:R:Y125 6.67 0 No Yes 0 6 0 1
L:L:V3 R:R:Y125 5.05 6 No Yes 0 6 0 1
R:R:Y126 R:R:Y130 5.96 6 Yes Yes 5 8 1 2
R:R:S176 R:R:Y126 2.54 6 Yes Yes 7 5 2 1
R:R:A179 R:R:Y126 5.34 0 No Yes 5 5 2 1
L:L:V3 R:R:Y126 7.57 6 No Yes 0 5 0 1
R:R:V129 R:R:Y130 5.05 0 No Yes 7 8 2 2
R:R:E198 R:R:R183 11.63 0 No Yes 5 6 2 2
R:R:D188 R:R:V186 2.92 4 Yes No 1 1 1 1
R:R:V186 R:R:Y197 6.31 4 No Yes 1 4 1 1
L:L:P33 R:R:V186 5.3 4 Yes No 0 1 0 1
R:R:D188 R:R:P189 3.22 4 Yes Yes 1 2 1 1
R:R:D188 R:R:K192 12.44 4 Yes No 1 5 1 2
L:L:L7 R:R:D188 5.43 0 No Yes 0 1 0 1
R:R:K192 R:R:P189 3.35 4 No Yes 5 2 2 1
L:L:Q10 R:R:P189 4.74 4 No Yes 0 2 0 1
L:L:K29 R:R:P189 3.35 4 Yes Yes 0 2 0 1
R:R:R208 R:R:Y197 5.14 4 Yes Yes 4 4 1 1
L:L:L7 R:R:Y197 10.55 0 No Yes 0 4 0 1
L:L:P33 R:R:Y197 2.78 4 Yes Yes 0 4 0 1
R:R:E198 R:R:R208 4.65 0 No Yes 5 4 2 1
L:L:P33 R:R:N199 4.89 4 Yes No 0 4 0 1
R:R:R208 R:R:R212 3.2 4 Yes Yes 4 5 1 1
L:L:E6 R:R:R208 10.47 4 Yes Yes 0 4 0 1
R:R:N271 R:R:R212 8.44 0 No Yes 5 5 2 1
R:R:D274 R:R:R212 9.53 4 Yes Yes 5 5 1 1
R:R:R212 R:R:T275 6.47 4 Yes No 5 5 1 2
R:R:R212 R:R:R278 2.13 4 Yes Yes 5 4 1 1
L:L:E6 R:R:R212 4.65 4 Yes Yes 0 5 0 1
R:R:L296 R:R:N271 2.75 0 No No 4 5 1 2
R:R:D274 R:R:R278 8.34 4 Yes Yes 5 4 1 1
R:R:D274 R:R:I292 4.2 4 Yes No 5 5 1 2
L:L:R8 R:R:D274 8.34 4 Yes Yes 0 5 0 1
R:R:I292 R:R:L277 4.28 0 No No 5 3 2 1
L:L:R8 R:R:L277 2.43 4 Yes No 0 3 0 1
L:L:E6 R:R:R278 4.65 4 Yes Yes 0 4 0 1
L:L:R8 R:R:R278 3.2 4 Yes Yes 0 4 0 1
R:R:D284 R:R:R280 7.15 0 No No 1 2 1 2
L:L:L12 R:R:D284 13.57 0 No No 0 1 0 1
L:L:R8 R:R:R289 9.6 4 Yes No 0 3 0 1
L:L:L12 R:R:R289 3.64 0 No No 0 3 0 1
L:L:E6 R:R:N293 2.63 4 Yes No 0 4 0 1
L:L:R8 R:R:N293 8.44 4 Yes No 0 4 0 1
L:L:E6 R:R:L296 6.63 4 Yes No 0 4 0 1
L:L:A4 R:R:A297 1.79 0 No No 0 5 0 1
R:R:L301 R:R:S300 3 0 Yes No 5 7 2 1
L:L:A4 R:R:S300 3.42 0 No No 0 7 0 1
R:R:V36 R:R:V38 1.6 0 No No 3 4 1 1
R:R:N199 R:R:S184 1.49 0 No No 4 4 1 2
R:R:N293 R:R:V44 1.48 4 No No 4 4 1 2
R:R:E35 R:R:L34 1.33 0 No No 3 2 1 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

ShowSimilarityNetwork TypeNameLigandDescription

PDB Summary
PDB 9EJC
Class A
SubFamily Other
Type Uclassified
SubType ORF74
Species Human gammaherpesvirus 8
Ligand CXCL1
Other Ligand(s) -
Protein Partners Gi1/Beta1/Gamma2
PDB Resolution 2.98
Date 2025-09-03
D.O.I. doi.org/10.1038/s41467-025-63457-4
Net Summary
Imin 1.71
Number of Linked Nodes 919
Number of Links 1158
Number of Hubs 205
Number of Links mediated by Hubs 728
Number of Communities 29
Number of Nodes involved in Communities 305
Number of Links involved in Communities 444
Path Summary
Number Of Nodes in MetaPath 94
Number Of Links MetaPath 93
Number of Shortest Paths 973086
Length Of Smallest Path 3
Average Path Length 23.0425
Length of Longest Path 57
Minimum Path Strength 1.36
Average Path Strength 5.18517
Maximum Path Strength 19.655
Minimum Path Correlation 0.71
Average Path Correlation 0.979837
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.63158
Average % Of Corr. Nodes 56.7446
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 57.5434
Maximum Path Hubs % 100

Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>9EJC_Chain_B
DQLRQEAEQ LKNQIRDAR KACADATLS QITNNIDPV GRIQMRTRR 
TLRGHLAKI YAMHWGTDS RLLVSASQD GKLIIWDSY TTNKVHAIP 
LRSSWVMTC AYAPSGNYV ACGGLDNIC SIYNLKTRE GNVRVSREL 
AGHTGYLSC CRFLDDNQI VTSSGDTTC ALWDIETGQ QTTTFTGHT 
GDVMSLSLA PDTRLFVSG ACDASAKLW DVREGMCRQ TFTGHESDI 
NAICFFPNG NAFATGSDD ATCRLFDLR ADQELMTYS HDNIICGIT 
SVSFSKSGR LLLAGYDDF NCNVWDALK ADRAGVLAG HDNRVSCLG 
VTDDGMAVA TGSWDSFLK IWN


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>9EJC_Chain_G
IAQARKLVE QLKMEANID RIKVSKAAA DLMAYCEAH AKEDPLLTP 
VPASENPF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ98146
Sequence
>9EJC_Chain_R
CNFSLEVSV CEMTTVVPY TWNVGILSL IFLINVLGN GLVTYIFCK 
HRSRAGAID ILLLGICLN SLCLSISLL AEVLMFLFP NIISTGLCR 
LEIFFYYLY VYLDIFSVV CVSLVRYLL VAYSTRSWP KKQSLGWVL 
TSAAWLIAL VLSGDACRH RSRVVDPVS KQAMCYENA GNMTADWRL 
HVRTVSVTA GFLLPLALL ILFYALTWC VVRRTKLQA RRKVRGVIV 
AVVVLFFVF CFPYHVLNL LDTLLRRRW IRDSCYTRG LINVGLAVT 
SLLQALYSA VVPLIYSCL GSLFRQRMY GLFQS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainA
ProteinG Protein α Sub unit
UniProtP63096
Sequence
>9EJC_Chain_A
TLSAEDKAA VERSKMIDR NLREDGEKA AREVKLLLL GAGESGKST 
IVKQMKITG IVETHFTFK DLHFKMFDV GGQRSERKK WIHCFEGVT 
AIIFCVALS DYDLVNRMH ESMKLFDSI CNNKWFTDT SIILFLNKK 
DLFEEKIKK SPLTICYPE YAGSNTYEE AAAYIQCQF EDLNKRKDT 
KEIYTHFTC ATDTKNVQF VFDAVTDVI IKNNLKDCG LF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9EJCAOtherUclassifiedORF74Human gammaherpesvirus 8CXCL1-Gi1/β1/γ22.982025-09-03doi.org/10.1038/s41467-025-63457-4
9EJC (No Gprot) AOtherUclassifiedORF74Human gammaherpesvirus 8CXCL1-2.982025-09-03doi.org/10.1038/s41467-025-63457-4
8W1AAOtherUclassifiedORF74Human gammaherpesvirus 8---2.892025-08-27To be published




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