psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I20	R:R:Q23	10.98	No	No	0	4	3
2	R:R:E271	R:R:T21	16.93	No	No	0	2	4
3	R:R:T21	R:R:Y275	3.75	No	No	0	4	2
4	R:R:I24	R:R:L28	4.28	No	No	0	6	5
5	R:R:I24	R:R:Y275	19.34	No	No	0	6	2
6	R:R:I25	R:R:P26	5.08	Yes	No	0	6	5
7	R:R:I25	R:R:Y29	8.46	Yes	Yes	2	6	8
8	R:R:I25	R:R:R274	3.76	Yes	No	2	6	3
9	R:R:E278	R:R:I25	12.3	Yes	Yes	2	5	6
10	R:R:F279	R:R:L28	9.74	No	No	0	5	5
11	R:R:F33	R:R:Y29	13.41	Yes	Yes	2	7	8
12	R:R:D81	R:R:Y29	17.24	No	Yes	0	5	8
13	R:R:E278	R:R:Y29	28.06	Yes	Yes	2	5	8
14	R:R:C30	R:R:I78	3.27	No	No	2	4	7
15	R:R:C30	R:R:S82	6.89	No	Yes	2	4	4
16	R:R:F33	R:R:V32	3.93	Yes	No	2	7	7
17	R:R:L282	R:R:V32	8.94	No	No	2	5	7
18	R:R:F33	R:R:F74	18.22	Yes	Yes	0	7	8
19	R:R:F33	R:R:I78	5.02	Yes	No	2	7	7
20	R:R:F33	R:R:L282	13.4	Yes	No	2	7	5
21	R:R:I34	R:R:I37	5.89	No	No	0	5	7
22	R:R:G36	R:R:N40	5.09	No	Yes	0	8	9
23	R:R:F74	R:R:I37	6.28	Yes	No	0	8	7
24	R:R:C289	R:R:N40	9.45	No	Yes	0	8	9
25	R:R:G41	R:R:S71	3.71	No	No	0	4	6
26	R:R:V42	R:R:W45	4.9	No	No	0	7	4
27	R:R:P292	R:R:S43	5.34	No	No	0	9	8
28	R:R:I46	R:R:W45	7.05	No	No	0	7	4
29	R:R:F47	R:R:L60	6.09	Yes	No	0	7	8
30	R:R:F47	R:R:V64	11.8	Yes	No	1	7	9
31	R:R:F47	R:R:Y295	26.82	Yes	Yes	1	7	9
32	R:R:F302	R:R:F47	18.22	No	Yes	1	9	7
33	R:R:F48	R:R:V64	9.18	No	No	0	4	9
34	R:R:F48	R:R:I65	8.79	No	No	0	4	5
35	R:R:F48	R:R:F68	12.86	No	No	0	4	7
36	R:R:K61	R:R:V50	9.11	No	No	0	6	5
37	R:R:I305	R:R:P51	3.39	No	No	0	5	6
38	R:R:P301	R:R:S52	3.56	No	No	0	6	6
39	R:R:I57	R:R:S53	12.39	No	No	0	7	5
40	R:R:Q133	R:R:S55	8.66	No	No	0	7	7
41	R:R:S138	R:R:S55	3.26	No	No	0	8	7
42	R:R:K139	R:R:S55	3.06	No	No	0	5	7
43	R:R:I57	R:R:L60	5.71	No	No	0	7	8
44	R:R:C299	R:R:I57	3.27	No	No	0	8	7
45	R:R:I58	R:R:S138	3.1	No	No	0	6	8
46	R:R:I58	R:R:K139	5.82	No	No	0	6	5
47	R:R:I58	R:R:S142	4.64	No	No	0	6	7
48	R:R:L114	R:R:Y59	4.69	No	Yes	0	7	7
49	R:R:I115	R:R:Y59	4.84	No	Yes	0	9	7
50	R:R:D118	R:R:Y59	8.05	No	Yes	0	8	7
51	R:R:S138	R:R:Y59	8.9	No	Yes	0	8	7
52	R:R:F111	R:R:N62	9.67	Yes	No	0	8	9
53	R:R:N62	R:R:S142	8.94	No	No	0	9	7
54	R:R:F111	R:R:I63	5.02	Yes	No	0	8	9
55	R:R:F112	R:R:I63	3.77	Yes	No	1	9	9
56	R:R:D291	R:R:I63	5.6	Yes	No	1	9	9
57	R:R:V64	R:R:Y295	10.09	No	Yes	1	9	9
58	R:R:I65	R:R:W146	5.87	No	Yes	0	5	9
59	R:R:A66	R:R:N104	3.13	No	No	0	8	8
60	R:R:D67	R:R:M70	4.16	Yes	Yes	1	9	7
61	R:R:D67	R:R:N287	12.12	Yes	Yes	1	9	9
62	R:R:D67	R:R:V288	13.15	Yes	No	1	9	8
63	R:R:D291	R:R:D67	5.32	Yes	Yes	1	9	9
64	R:R:F68	R:R:L72	21.92	No	No	0	7	4
65	R:R:L100	R:R:V69	4.47	No	No	0	5	7
66	R:R:N104	R:R:V69	10.35	No	No	0	8	7
67	R:R:F101	R:R:M70	6.22	No	Yes	0	7	7
68	R:R:M70	R:R:S108	3.07	Yes	No	1	7	9
69	R:R:M70	R:R:N287	4.21	Yes	Yes	1	7	9
70	R:R:M70	R:R:V288	3.04	Yes	No	1	7	8
71	R:R:L100	R:R:T73	4.42	No	No	0	5	7
72	R:R:A285	R:R:F74	4.16	No	Yes	0	7	8
73	R:R:F76	R:R:S97	3.96	No	Yes	0	6	5
74	R:R:I78	R:R:S82	3.1	No	Yes	2	7	4
75	R:R:D81	R:R:S82	4.42	No	Yes	0	5	4
76	R:R:L84	R:R:S82	4.5	Yes	Yes	0	3	4
77	R:R:G85	R:R:P86	4.06	No	No	4	4	4
78	R:R:G85	R:R:L89	5.13	No	No	4	4	7
79	R:R:P86	R:R:Q88	6.32	No	No	0	4	2
80	R:R:L89	R:R:P86	9.85	No	No	4	7	4
81	R:R:Q88	R:R:W87	3.29	No	No	0	2	9
82	R:R:I170	R:R:W87	4.7	No	No	0	3	9
83	R:R:K171	R:R:W87	5.8	No	No	0	3	9
84	R:R:E174	R:R:N90	7.89	Yes	No	0	5	7
85	R:R:Q162	R:R:V91	8.6	Yes	No	3	5	3
86	R:R:E174	R:R:V91	18.54	Yes	No	3	5	3
87	R:R:F92	R:R:V96	6.55	No	No	0	3	4
88	R:R:S97	R:R:V93	4.85	Yes	No	0	5	6
89	R:R:C94	R:R:L175	4.76	No	No	0	9	5
90	R:R:R95	R:R:V96	5.23	No	No	0	8	4
91	R:R:I158	R:R:R95	3.76	No	No	0	4	8
92	R:R:V154	R:R:V99	3.21	Yes	No	0	5	6
93	R:R:F101	R:R:Y102	5.16	No	Yes	0	7	5
94	R:R:Y102	R:R:Y106	4.96	Yes	Yes	1	5	8
95	R:R:N188	R:R:Y102	6.98	No	Yes	1	4	5
96	R:R:R253	R:R:Y102	3.09	Yes	Yes	1	6	5
97	R:R:L281	R:R:Y102	3.52	No	Yes	0	6	5
98	R:R:V103	R:R:V154	3.21	No	Yes	0	6	5
99	R:R:N104	R:R:W146	4.52	No	Yes	0	8	9
100	R:R:M105	R:R:Y106	3.59	No	Yes	0	8	8
101	R:R:F246	R:R:M105	3.73	Yes	No	0	9	8
102	R:R:M105	R:R:S284	3.07	No	No	0	8	8
103	R:R:I109	R:R:Y106	6.04	No	Yes	0	8	8
104	R:R:F191	R:R:Y106	20.63	Yes	Yes	0	5	8
105	R:R:H250	R:R:Y106	7.62	Yes	Yes	1	8	8
106	R:R:R253	R:R:Y106	5.14	Yes	Yes	1	6	8
107	R:R:F111	R:R:V107	3.93	Yes	No	0	8	7
108	R:R:V107	R:R:W146	4.9	No	Yes	0	7	9
109	R:R:M149	R:R:V107	6.09	No	No	0	8	7
110	R:R:N287	R:R:S108	4.47	Yes	No	1	9	9
111	R:R:F195	R:R:I109	8.79	Yes	No	0	9	8
112	R:R:F246	R:R:I109	8.79	Yes	No	0	9	8
113	R:R:I194	R:R:V110	3.07	No	No	0	6	6
114	R:R:F111	R:R:V145	7.87	Yes	No	0	8	7
115	R:R:F112	R:R:F242	3.22	Yes	Yes	1	9	9
116	R:R:F112	R:R:F246	4.29	Yes	Yes	1	9	9
117	R:R:D291	R:R:F112	4.78	Yes	Yes	1	9	9
118	R:R:F112	R:R:I294	3.77	Yes	Yes	1	9	8
119	R:R:L202	R:R:S116	6.01	No	Yes	0	8	9
120	R:R:F205	R:R:S116	10.57	Yes	Yes	0	8	9
121	R:R:S116	R:R:Y206	10.17	Yes	Yes	0	9	9
122	R:R:F117	R:R:F205	23.58	No	Yes	0	6	8
123	R:R:D118	R:R:K122	11.06	No	No	0	8	8
124	R:R:D118	R:R:V135	5.84	No	No	0	8	3
125	R:R:R119	R:R:Y206	3.09	No	Yes	0	9	9
126	R:R:I235	R:R:R119	3.76	Yes	No	0	8	9
127	R:R:L298	R:R:R119	4.86	Yes	No	0	7	9
128	R:R:V124	R:R:Y120	10.09	Yes	No	0	8	8
129	R:R:F205	R:R:Y120	11.35	Yes	No	0	8	8
130	R:R:A208	R:R:Y120	5.34	No	No	0	4	8
131	R:R:L127	R:R:Y121	4.69	No	No	0	6	6
132	R:R:W128	R:R:Y121	23.15	No	No	0	4	6
133	R:R:V135	R:R:Y121	27.76	No	No	0	3	6
134	R:R:I123	R:R:V124	4.61	No	Yes	0	8	8
135	R:R:I123	R:R:I209	4.42	No	No	0	8	8
136	R:R:K125	R:R:V124	3.04	No	Yes	0	6	8
137	R:R:K212	R:R:V124	4.55	No	Yes	0	5	8
138	R:R:K125	R:R:P126	3.35	No	No	0	6	7
139	R:R:K125	R:R:W128	10.44	No	No	0	6	4
140	R:R:L127	R:R:T129	4.42	No	No	0	6	6
141	R:R:L127	R:R:S134	3	No	No	0	6	7
142	R:R:S130	R:R:S136	3.26	No	No	0	5	4
143	R:R:S130	R:R:Y137	10.17	No	Yes	0	5	3
144	R:R:I132	R:R:Q133	5.49	No	No	0	3	7
145	R:R:I132	R:R:Y137	3.63	No	Yes	0	3	3
146	R:R:L140	R:R:Y137	5.86	No	Yes	0	3	3
147	R:R:L141	R:R:Y137	9.38	No	Yes	0	6	3
148	R:R:I144	R:R:L140	4.28	No	No	0	2	3
149	R:R:I144	R:R:V145	3.07	No	No	0	2	7
150	R:R:L150	R:R:W146	6.83	No	Yes	0	3	9
151	R:R:L148	R:R:L152	9.69	No	No	0	4	5
152	R:R:F191	R:R:M149	4.98	Yes	No	0	5	8
153	R:R:S187	R:R:V154	3.23	No	Yes	0	4	5
154	R:R:F191	R:R:V154	5.24	Yes	Yes	0	5	5
155	R:R:N156	R:R:P155	4.89	No	No	0	5	7
156	R:R:I157	R:R:I158	4.42	No	No	0	5	4
157	R:R:E178	R:R:T160	8.47	Yes	No	0	2	5
158	R:R:E166	R:R:Q162	8.92	No	Yes	0	2	5
159	R:R:E174	R:R:Q162	3.82	Yes	Yes	3	5	5
160	R:R:Q162	R:R:S177	5.78	Yes	No	3	5	3
161	R:R:L179	R:R:V164	7.45	No	No	0	2	2
162	R:R:I173	R:R:T168	7.6	No	No	0	4	3
163	R:R:C172	R:R:Q169	7.63	No	No	0	9	1
164	R:R:I173	R:R:Q169	4.12	No	No	0	4	1
165	R:R:E174	R:R:S177	5.75	Yes	No	3	5	3
166	R:R:E178	R:R:K182	4.05	Yes	No	0	2	1
167	R:R:E178	R:R:H184	3.69	Yes	No	0	2	3
168	R:R:G180	R:R:L179	6.84	No	No	0	3	2
169	R:R:R181	R:R:W183	11	No	No	0	2	2
170	R:R:H184	R:R:N188	19.13	No	No	0	3	4
171	R:R:N188	R:R:R253	4.82	No	Yes	1	4	6
172	R:R:H250	R:R:V192	5.54	Yes	No	0	8	5
173	R:R:R253	R:R:V192	6.54	Yes	No	0	6	5
174	R:R:F195	R:R:W196	10.02	Yes	No	1	9	4
175	R:R:F195	R:R:F199	5.36	Yes	Yes	1	9	7
176	R:R:F195	R:R:F242	6.43	Yes	Yes	1	9	9
177	R:R:F195	R:R:H250	35.07	Yes	Yes	1	9	8
178	R:R:F199	R:R:W196	7.02	Yes	No	1	7	4
179	R:R:H250	R:R:W196	3.17	Yes	No	1	8	4
180	R:R:F199	R:R:F242	5.36	Yes	Yes	1	7	9
181	R:R:F199	R:R:F243	7.5	Yes	Yes	1	7	7
182	R:R:F199	R:R:V247	9.18	Yes	No	0	7	5
183	R:R:F205	R:R:L201	9.74	Yes	No	0	8	7
184	R:R:F242	R:R:L202	6.09	Yes	No	0	9	8
185	R:R:I209	R:R:Y206	8.46	No	Yes	0	8	9
186	R:R:I238	R:R:Y206	9.67	No	Yes	0	8	9
187	R:R:V239	R:R:Y206	5.05	No	Yes	0	8	9
188	R:R:I209	R:R:I235	5.89	No	Yes	0	8	8
189	R:R:F236	R:R:T210	7.78	No	No	0	5	5
190	R:R:H217	R:R:I213	3.98	No	No	0	4	8
191	R:R:I213	R:R:I235	5.89	No	Yes	0	8	8
192	R:R:L298	R:R:N234	8.24	Yes	No	0	7	8
193	R:R:F236	R:R:I235	3.77	No	Yes	0	5	8
194	R:R:F236	R:R:V239	5.24	No	No	0	5	8
195	R:R:L298	R:R:S237	3	Yes	No	0	7	6
196	R:R:I238	R:R:L298	5.71	No	Yes	0	8	7
197	R:R:F243	R:R:V239	3.93	Yes	No	0	7	8
198	R:R:F240	R:R:V244	7.87	No	No	0	5	6
199	R:R:L290	R:R:V241	5.96	No	No	0	7	7
200	R:R:I294	R:R:V241	4.61	Yes	No	0	8	7
201	R:R:F242	R:R:F243	3.22	Yes	Yes	1	9	7
202	R:R:F242	R:R:F246	4.29	Yes	Yes	1	9	9
203	R:R:C245	R:R:F246	8.38	No	Yes	1	9	9
204	R:R:C245	R:R:N287	3.15	No	Yes	1	9	9
205	R:R:C245	R:R:L290	3.17	No	No	0	9	7
206	R:R:F246	R:R:N287	9.67	Yes	Yes	1	9	9
207	R:R:P248	R:R:V247	3.53	No	No	0	9	5
208	R:R:H250	R:R:Y249	8.71	Yes	Yes	0	8	7
209	R:R:R253	R:R:Y249	11.32	Yes	Yes	0	6	7
210	R:R:T280	R:R:Y249	6.24	No	Yes	0	7	7
211	R:R:L281	R:R:Y249	12.89	No	Yes	0	6	7
212	R:R:S284	R:R:Y249	5.09	No	Yes	0	8	7
213	R:R:A252	R:R:T280	5.03	No	No	0	5	7
214	R:R:I254	R:R:P255	3.39	No	No	0	5	5
215	R:R:L273	R:R:P255	3.28	No	No	0	4	5
216	R:R:Q260	R:R:Y256	13.53	No	Yes	0	3	5
217	R:R:K277	R:R:Y256	17.91	No	Yes	0	5	5
218	R:R:E262	R:R:K258	9.45	No	No	0	1	3
219	R:R:S259	R:R:Y265	7.63	No	No	0	3	1
220	R:R:K270	R:R:S259	9.18	No	No	0	3	3
221	R:R:K270	R:R:Q260	8.14	No	No	0	3	3
222	R:R:E262	R:R:Y265	4.49	No	No	0	1	1
223	R:R:Q268	R:R:S266	4.33	No	No	0	2	5
224	R:R:S266	R:R:S269	6.52	No	No	0	5	1
225	R:R:C267	R:R:E271	3.04	No	No	0	8	2
226	R:R:K270	R:R:S269	3.06	No	No	0	3	1
227	R:R:E278	R:R:R274	8.14	Yes	No	2	5	3
228	R:R:E278	R:R:Y275	5.61	Yes	No	0	5	2
229	R:R:E278	R:R:F279	3.5	Yes	No	0	5	5
230	R:R:D291	R:R:N287	4.04	Yes	Yes	1	9	9
231	R:R:D291	R:R:I294	5.6	Yes	Yes	1	9	8
232	R:R:D291	R:R:Y295	18.39	Yes	Yes	1	9	9
233	R:R:P292	R:R:Y295	6.95	No	Yes	0	9	9
234	R:R:F297	R:R:I293	7.54	No	No	0	8	7
235	R:R:I294	R:R:L298	4.28	Yes	Yes	0	8	7
236	R:R:F302	R:R:Y295	7.22	No	Yes	1	9	9
237	R:R:F296	R:R:F302	9.65	No	No	0	7	9
238	R:R:C299	R:R:P301	5.65	No	No	0	8	6
239	R:R:P301	R:R:Q300	3.16	No	No	0	6	5
240	R:R:Q300	R:R:R303	8.18	No	No	0	5	8
241	R:R:E304	R:R:Q300	5.1	No	No	0	5	5
242	R:R:C307	R:R:K308	3.23	No	No	0	4	6
243	R:R:N40	R:R:V288	2.96	Yes	No	0	9	8
244	R:R:N90	R:R:V93	2.96	No	No	0	7	6
245	R:R:I173	R:R:K176	2.91	No	No	0	4	4
246	R:R:I197	R:R:L201	2.85	No	No	0	6	7
247	R:R:E174	R:R:T168	2.82	Yes	No	0	5	3
248	R:R:E262	R:R:T261	2.82	No	No	0	1	1
249	R:R:A285	R:R:F101	2.77	No	No	0	7	7
250	R:R:A153	R:R:F191	2.77	No	Yes	0	7	5
251	R:R:A193	R:R:Y189	2.67	No	No	0	4	4
252	R:R:N161	R:R:Q162	2.64	No	Yes	0	4	5
253	R:R:F297	R:R:S237	2.64	No	No	0	8	6
254	R:R:E178	R:R:N156	2.63	Yes	No	0	2	5
255	R:R:F47	R:R:V50	2.62	Yes	No	0	7	5
256	R:R:F242	R:R:V198	2.62	Yes	No	0	9	9
257	R:R:R165	R:R:T168	2.59	No	No	0	2	3
258	R:R:F214	R:R:T210	2.59	No	No	0	4	5
259	R:R:T257	R:R:Y256	2.5	No	Yes	0	5	5
260	R:R:F56	R:R:K122	2.48	No	No	0	8	8
261	R:R:F74	R:R:K77	2.48	Yes	No	0	8	7
262	R:R:K277	R:R:R274	2.48	No	No	0	5	3
263	R:R:F296	R:R:L306	2.44	No	No	0	7	7
264	R:R:L273	R:R:Y256	2.34	No	Yes	0	4	5
265	R:R:F131	R:R:Y137	2.06	No	Yes	0	4	3
266	R:R:F68	R:R:W45	2	No	No	0	7	4
267	R:R:A35	R:R:G36	1.95	No	No	0	5	8
268	R:R:G113	R:R:S116	1.86	No	Yes	0	7	9
269	R:R:A286	R:R:C289	1.81	No	No	0	4	8
270	R:R:P51	R:R:S52	1.78	No	No	0	6	6
271	R:R:G83	R:R:L84	1.71	No	Yes	0	5	3
272	R:R:G85	R:R:L84	1.71	No	Yes	0	4	3
273	R:R:C94	R:R:V91	1.71	No	No	0	9	3
274	R:R:A98	R:R:S97	1.71	No	Yes	0	6	5
275	R:R:G41	R:R:N40	1.7	No	Yes	0	4	9
276	R:R:G80	R:R:N90	1.7	No	No	0	5	7
277	R:R:L151	R:R:P155	1.64	No	No	0	4	7
278	R:R:L159	R:R:P155	1.64	No	No	0	5	7
279	R:R:S163	R:R:S177	1.63	No	No	0	2	3
280	R:R:A193	R:R:I190	1.62	No	No	0	4	5
281	R:R:A252	R:R:M276	1.61	No	No	0	5	5
282	R:R:V110	R:R:V145	1.6	No	No	0	6	7
283	R:R:V110	R:R:V198	1.6	No	No	0	6	9
284	R:R:P26	R:R:Q22	1.58	No	No	0	5	4
285	R:R:I251	R:R:V247	1.54	No	No	0	5	5
286	R:R:K77	R:R:S97	1.53	No	Yes	0	7	5
287	R:R:M147	R:R:V143	1.52	No	No	0	4	3
288	R:R:G180	R:R:R181	1.5	No	No	0	3	2
289	R:R:I20	R:R:I24	1.47	No	No	0	4	6
290	R:R:F74	R:R:P75	1.44	Yes	No	0	8	9
291	R:R:I157	R:R:L151	1.43	No	No	0	5	4
292	R:R:I158	R:R:L159	1.43	No	No	0	4	5
293	R:R:E166	R:R:V167	1.43	No	No	0	2	2
294	R:R:I203	R:R:L200	1.43	No	No	0	4	3
295	R:R:K230	R:R:N234	1.4	No	No	0	7	8
296	R:R:P51	R:R:Y49	1.39	No	No	0	6	5
297	R:R:L79	R:R:L84	1.38	No	Yes	0	4	3
298	R:R:L79	R:R:L89	1.38	No	No	0	4	7
299	R:R:L39	R:R:N40	1.37	No	Yes	0	8	9
300	R:R:H217	R:R:K228	1.31	No	No	0	4	6
301	R:R:F240	R:R:V241	1.31	No	No	0	5	7
302	R:R:F243	R:R:I203	1.26	Yes	No	0	7	4
303	R:R:K185	R:R:R181	1.24	No	No	0	3	2
304	R:R:K229	R:R:R233	1.24	No	No	0	5	5
305	R:R:K185	R:R:Y189	1.19	No	No	0	3	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I25	7.4	4	2	6
2	R:R:Y29	16.7925	4	2	8
3	R:R:F33	10.796	5	2	7
4	R:R:N40	4.114	5	0	9
5	R:R:F47	13.11	5	1	7
6	R:R:Y59	6.62	4	0	7
7	R:R:D67	8.6875	4	1	9
8	R:R:M70	4.14	5	1	7
9	R:R:F74	6.516	5	0	8
10	R:R:S82	4.7275	4	2	4
11	R:R:L84	2.325	4	0	3
12	R:R:S97	3.0125	4	0	5
13	R:R:Y102	4.742	5	1	5
14	R:R:Y106	7.99667	6	1	8
15	R:R:F111	6.6225	4	0	8
16	R:R:F112	3.966	5	1	9
17	R:R:S116	7.1525	4	0	9
18	R:R:V124	5.5725	4	0	8
19	R:R:Y137	6.22	5	0	3
20	R:R:W146	5.53	4	0	9
21	R:R:V154	3.7225	4	0	5
22	R:R:Q162	5.952	5	3	5
23	R:R:E174	7.764	5	3	5
24	R:R:E178	4.71	4	0	2
25	R:R:F191	8.405	4	0	5
26	R:R:F195	13.134	5	1	9
27	R:R:F199	6.884	5	1	7
28	R:R:F205	13.81	4	0	8
29	R:R:Y206	7.288	5	0	9
30	R:R:I235	4.8275	4	0	8
31	R:R:F242	4.46143	7	1	9
32	R:R:F243	3.9775	4	1	7
33	R:R:F246	6.525	6	1	9
34	R:R:Y249	8.85	5	0	7
35	R:R:H250	12.022	5	1	8
36	R:R:R253	6.182	5	1	6
37	R:R:Y256	9.07	4	0	5
38	R:R:E278	11.522	5	2	5
39	R:R:N287	6.27667	6	1	9
40	R:R:D291	7.28833	6	1	9
41	R:R:I294	4.565	4	1	8
42	R:R:Y295	13.894	5	1	9
43	R:R:L298	5.218	5	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E278	R:R:Y29	33.4541	28.06	Yes	Yes	2	5	8
2	R:R:E278	R:R:R274	21.7187	8.14	Yes	No	2	5	3
3	R:R:F33	R:R:Y29	57.8525	13.41	Yes	Yes	2	7	8
4	R:R:F33	R:R:I78	16.9617	5.02	Yes	No	2	7	7
5	R:R:F33	R:R:F74	76.9359	18.22	Yes	Yes	0	7	8
6	R:R:N40	R:R:V288	11.4988	2.96	Yes	No	0	9	8
7	R:R:F101	R:R:M70	85.7439	6.22	No	Yes	0	7	7
8	R:R:A285	R:R:F101	100	2.77	No	No	0	7	7
9	R:R:A285	R:R:F74	99.2719	4.16	No	Yes	0	7	8
10	R:R:D67	R:R:M70	32.4155	4.16	Yes	Yes	1	9	7
11	R:R:D291	R:R:D67	37.9967	5.32	Yes	Yes	1	9	9
12	R:R:D291	R:R:Y295	43.1159	18.39	Yes	Yes	1	9	9
13	R:R:V64	R:R:Y295	10.2643	10.09	No	Yes	1	9	9
14	R:R:F48	R:R:V64	10.2347	9.18	No	No	0	4	9
15	R:R:M70	R:R:N287	50.3826	4.21	Yes	Yes	1	7	9
16	R:R:D291	R:R:N287	35.3428	4.04	Yes	Yes	1	9	9
17	R:R:F47	R:R:Y295	23.9475	26.82	Yes	Yes	1	7	9
18	R:R:F47	R:R:L60	20.4325	6.09	Yes	No	0	7	8
19	R:R:F101	R:R:Y102	29.8762	5.16	No	Yes	0	7	5
20	R:R:Y102	R:R:Y106	30.5563	4.96	Yes	Yes	1	5	8
21	R:R:F191	R:R:Y106	21.3121	20.63	Yes	Yes	0	5	8
22	R:R:F191	R:R:M149	12.5744	4.98	Yes	No	0	5	8
23	R:R:M149	R:R:V107	12.0421	6.09	No	No	0	8	7
24	R:R:V107	R:R:W146	10.6598	4.9	No	Yes	0	7	9
25	R:R:I57	R:R:L60	18.7729	5.71	No	No	0	7	8
26	R:R:C299	R:R:I57	15.4204	3.27	No	No	0	8	7
27	R:R:C299	R:R:P301	13.7424	5.65	No	No	0	8	6
28	R:R:D291	R:R:I63	28.1685	5.6	Yes	No	1	9	9
29	R:R:F111	R:R:I63	33.2397	5.02	Yes	No	0	8	9
30	R:R:F111	R:R:N62	22.0551	9.67	Yes	No	0	8	9
31	R:R:N62	R:R:S142	20.6357	8.94	No	No	0	9	7
32	R:R:I58	R:R:S142	19.416	4.64	No	No	0	6	7
33	R:R:I58	R:R:S138	14.0824	3.1	No	No	0	6	8
34	R:R:F111	R:R:V145	12.8775	7.87	Yes	No	0	8	7
35	R:R:I144	R:R:V145	12.7407	3.07	No	No	0	2	7
36	R:R:I144	R:R:L140	11.3473	4.28	No	No	0	2	3
37	R:R:L140	R:R:Y137	10.0166	5.86	No	Yes	0	3	3
38	R:R:S138	R:R:Y59	10.852	8.9	No	Yes	0	8	7
39	R:R:F246	R:R:N287	20.2181	9.67	Yes	Yes	1	9	9
40	R:R:K77	R:R:S97	29.2996	1.53	No	Yes	0	7	5
41	R:R:F74	R:R:K77	30.5526	2.48	Yes	No	0	8	7
42	R:R:L84	R:R:S82	15.1617	4.5	Yes	Yes	0	3	4
43	R:R:E174	R:R:N90	21.6263	7.89	Yes	No	0	5	7
44	R:R:N90	R:R:V93	24.2136	2.96	No	No	0	7	6
45	R:R:S97	R:R:V93	25.4962	4.85	Yes	No	0	5	6
46	R:R:I158	R:R:R95	11.1846	3.76	No	No	0	4	8
47	R:R:I158	R:R:L159	14.8734	1.43	No	No	0	4	5
48	R:R:L159	R:R:P155	18.5733	1.64	No	No	0	5	7
49	R:R:N156	R:R:P155	29.684	4.89	No	No	0	5	7
50	R:R:E178	R:R:N156	33.358	2.63	Yes	No	0	2	5
51	R:R:E178	R:R:H184	43.5816	3.69	Yes	No	0	2	3
52	R:R:H184	R:R:N188	47.2334	19.13	No	No	0	3	4
53	R:R:N188	R:R:Y102	26.6125	6.98	No	Yes	1	4	5
54	R:R:M105	R:R:Y106	10.9481	3.59	No	Yes	0	8	8
55	R:R:I109	R:R:Y106	20.1478	6.04	No	Yes	0	8	8
56	R:R:H250	R:R:Y106	15.4833	7.62	Yes	Yes	1	8	8
57	R:R:F195	R:R:I109	10.0943	8.79	Yes	No	0	9	8
58	R:R:F195	R:R:H250	19.3273	35.07	Yes	Yes	1	9	8
59	R:R:F242	R:R:F246	28.2462	4.29	Yes	Yes	1	9	9
60	R:R:D291	R:R:I294	28.941	5.6	Yes	Yes	1	9	8
61	R:R:F242	R:R:L202	28.808	6.09	Yes	No	0	9	8
62	R:R:L202	R:R:S116	27.5143	6.01	No	Yes	0	8	9
63	R:R:F205	R:R:S116	21.8	10.57	Yes	Yes	0	8	9
64	R:R:I294	R:R:L298	31.521	4.28	Yes	Yes	0	8	7
65	R:R:L298	R:R:R119	16.8361	4.86	Yes	No	0	7	9
66	R:R:F242	R:R:F243	16.6771	3.22	Yes	Yes	1	9	7
67	R:R:F243	R:R:V239	20.6283	3.93	Yes	No	0	7	8
68	R:R:I235	R:R:R119	10.4158	3.76	Yes	No	0	8	9
69	R:R:F205	R:R:Y120	15.62	11.35	Yes	No	0	8	8
70	R:R:V124	R:R:Y120	12.6631	10.09	Yes	No	0	8	8
71	R:R:K125	R:R:V124	14.8106	3.04	No	Yes	0	6	8
72	R:R:K125	R:R:W128	10.8261	10.44	No	No	0	6	4
73	R:R:I123	R:R:I209	12.1161	4.42	No	No	0	8	8
74	R:R:I209	R:R:Y206	14.1194	8.46	No	Yes	0	8	9
75	R:R:F195	R:R:F199	10.3456	5.36	Yes	Yes	1	9	7
76	R:R:F236	R:R:V239	12.2048	5.24	No	No	0	5	8
77	R:R:K277	R:R:R274	40.5286	2.48	No	No	0	5	3
78	R:R:K277	R:R:Y256	38.0262	17.91	No	Yes	0	5	5
79	R:R:Q260	R:R:Y256	25.7143	13.53	No	Yes	0	3	5
80	R:R:S259	R:R:Y265	10.3752	7.63	No	No	0	3	1
81	R:R:K270	R:R:S259	12.9477	9.18	No	No	0	3	3
82	R:R:K270	R:R:Q260	23.1713	8.14	No	No	0	3	3
83	R:R:I25	R:R:Y29	24.7274	8.46	Yes	Yes	2	6	8
84	R:R:I25	R:R:R274	21.1643	3.76	Yes	No	2	6	3
85	R:R:I78	R:R:S82	14.282	3.1	No	Yes	2	7	4
86	R:R:F111	R:R:V107	10.6524	3.93	Yes	No	0	8	7
87	R:R:F246	R:R:M105	12.8331	3.73	Yes	No	0	9	8
88	R:R:F246	R:R:I109	10.8815	8.79	Yes	No	0	9	8
89	R:R:F195	R:R:F242	18.6731	6.43	Yes	Yes	1	9	9
90	R:R:N188	R:R:R253	24.2506	4.82	No	Yes	1	4	6
91	R:R:R253	R:R:Y106	18.1519	5.14	Yes	Yes	1	6	8
92	R:R:F199	R:R:F243	10.1312	7.5	Yes	Yes	1	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9J05

PDB Summary
PDB	9J05
Class	A
SubFamily	Nucleotide
Type	P2Y
SubType	P2Y14
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.2
Date	2025-08-06
D.O.I.	To be published

Net Summary
I_min	3
Number of Linked Nodes	262
Number of Links	305
Number of Hubs	43
Number of Links mediated by Hubs	164
Number of Communities	4
Number of Nodes involved in Communities	42
Number of Links involved in Communities	62

Path Summary
Number Of Nodes in MetaPath	93
Number Of Links MetaPath	92
Number of Shortest Paths	64301
Length Of Smallest Path	3
Average Path Length	13.3748
Length of Longest Path	29
Minimum Path Strength	1.215
Average Path Strength	7.19251
Maximum Path Strength	25.455
Minimum Path Correlation	0.7
Average Path Correlation	0.91721
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	45.327
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.9717
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q15391
Sequence	>9J05_Chain_R I T Q Q I I P V L Y C M V F I A G I L L N G V S G W I F F Y V P S S K S F I I Y L K N I V I A D F V M S L T F P F K I L G D S G L G P W Q L N V F V C R V S A V L F Y V N M Y V S I V F F G L I S F D R Y Y K I V K P L W T S F I Q S V S Y S K L L S V I V W M L M L L L A V P N I I L T N Q S V R E V T Q I K C I E L K S E L G R K W H K A S N Y I F V A I F W I V F L L L I V F Y T A I T K K I F K S H S V K K K S S R N I F S I V F V F F V C F V P Y H I A R I P Y T K S Q T E A H Y S C Q S K E I L R Y M K E F T L L L S A A N V C L D P I I Y F F L C Q P F R E I L C K K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9J0F	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	NADH	-	Gi1/β1/γ2	2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0F (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	NADH	-		2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0I	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucuronic acid	-	Gi1/β1/γ2	2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9
	9J0I (No Gprot)	A	Nucleotide	P2Y	P2Y₁₄	Homo sapiens	UDP-Glucuronic acid	-		2.76	2025-06-04	doi.org/10.1038/s41421-025-00799-9

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9J05.zip

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