psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D88	17.62	Yes	No	1	0	6
2	L:L:?1	R:R:V89	16.58	Yes	No	0	0	4
3	L:L:?1	R:R:S92	6.96	Yes	No	0	0	6
4	L:L:?1	R:R:F167	4.52	Yes	Yes	1	0	4
5	L:L:?1	R:R:S177	4.18	Yes	Yes	0	0	5
6	L:L:?1	R:R:F251	21.46	Yes	No	1	0	6
7	L:L:?1	R:R:Y255	10.87	Yes	Yes	1	0	6
8	L:L:?1	R:R:F276	7.91	Yes	No	1	0	5
9	L:L:?1	R:R:Y280	5.44	Yes	Yes	1	0	7
10	R:R:K11	R:R:W277	8.12	No	Yes	0	5	4
11	R:R:A66	R:R:L15	4.73	No	No	0	6	6
12	R:R:L15	R:R:W277	12.53	No	Yes	0	6	4
13	R:R:I19	R:R:M62	5.83	No	Yes	0	5	7
14	R:R:A22	R:R:S284	3.42	No	No	0	7	7
15	R:R:D54	R:R:N26	5.39	Yes	No	5	9	9
16	R:R:N26	R:R:T55	5.85	No	No	0	9	8
17	R:R:N26	R:R:P287	6.52	No	No	5	9	9
18	R:R:L27	R:R:T31	4.42	No	No	0	3	4
19	R:R:V33	R:R:V48	4.81	No	No	0	7	5
20	R:R:E303	R:R:H36	3.69	No	No	0	4	5
21	R:R:L39	R:R:N44	8.24	Yes	No	0	8	8
22	R:R:I41	R:R:N44	8.5	No	No	0	7	8
23	R:R:T42	R:R:V125	4.76	No	No	0	6	7
24	R:R:D105	R:R:T43	7.23	No	No	0	9	8
25	R:R:F297	R:R:N44	9.67	Yes	No	0	8	8
26	R:R:C101	R:R:F46	5.59	No	Yes	6	6	7
27	R:R:F46	R:R:I102	3.77	Yes	No	0	7	8
28	R:R:D105	R:R:F46	3.58	No	Yes	0	9	7
29	R:R:F46	R:R:V125	11.8	Yes	No	0	7	7
30	R:R:F46	R:R:M128	3.73	Yes	No	6	7	5
31	R:R:F46	R:R:L129	4.87	Yes	No	0	7	7
32	R:R:F297	R:R:I47	7.54	Yes	No	0	8	8
33	R:R:H98	R:R:S49	11.16	Yes	No	7	8	9
34	R:R:L129	R:R:S49	7.51	No	No	0	7	9
35	R:R:S49	R:R:W133	3.71	No	No	7	9	9
36	R:R:D54	R:R:L50	8.14	Yes	No	0	9	9
37	R:R:H98	R:R:L50	3.86	Yes	No	0	8	9
38	R:R:D54	R:R:S95	4.42	Yes	No	0	9	9
39	R:R:D54	R:R:S283	5.89	Yes	No	0	9	9
40	R:R:D54	R:R:P287	4.83	Yes	No	5	9	9
41	R:R:F91	R:R:L56	18.27	Yes	No	0	6	6
42	R:R:S283	R:R:V57	4.85	No	No	0	9	7
43	R:R:A58	R:R:M62	4.83	No	Yes	0	7	7
44	R:R:F60	R:R:F83	3.22	No	No	4	5	4
45	R:R:C87	R:R:F60	6.98	No	No	4	4	5
46	R:R:F60	R:R:F91	5.36	No	Yes	4	5	6
47	R:R:A61	R:R:D88	4.63	No	No	1	6	6
48	R:R:A61	R:R:Y280	4	No	Yes	1	6	7
49	R:R:M62	R:R:Y280	14.37	Yes	Yes	0	7	7
50	R:R:M62	R:R:S283	3.07	Yes	No	0	7	9
51	R:R:F64	R:R:W84	20.04	No	No	0	4	6
52	R:R:N65	R:R:W277	12.43	No	Yes	1	6	4
53	R:R:N65	R:R:Y280	5.81	No	Yes	1	6	7
54	R:R:D273	R:R:T69	4.34	No	No	0	3	4
55	R:R:I70	R:R:S71	3.1	No	No	0	5	4
56	R:R:D163	R:R:R73	3.57	No	No	0	3	4
57	R:R:F76	R:R:W74	20.04	No	Yes	2	6	8
58	R:R:V80	R:R:W74	3.68	No	Yes	2	4	8
59	R:R:C81	R:R:W74	3.92	No	Yes	2	9	8
60	R:R:C165	R:R:W74	6.53	No	Yes	2	9	8
61	R:R:F76	R:R:V80	5.24	No	No	2	6	4
62	R:R:N77	R:R:T79	5.85	No	No	0	8	2
63	R:R:N77	R:R:V80	5.91	No	No	0	8	4
64	R:R:D82	R:R:Q78	3.92	No	No	0	5	3
65	R:R:K158	R:R:Q78	4.07	Yes	No	0	4	3
66	R:R:C165	R:R:C81	7.28	No	No	2	9	9
67	R:R:D82	R:R:I144	12.59	No	No	1	5	5
68	R:R:D82	R:R:Y149	10.34	No	Yes	1	5	5
69	R:R:C87	R:R:F83	8.38	No	No	4	4	4
70	R:R:N85	R:R:W84	3.39	No	No	0	4	6
71	R:R:F167	R:R:N85	19.33	Yes	No	0	4	4
72	R:R:F141	R:R:S86	6.61	No	No	0	5	5
73	R:R:I144	R:R:S86	9.29	No	No	0	5	5
74	R:R:C87	R:R:F91	4.19	No	Yes	4	4	6
75	R:R:D88	R:R:Y280	3.45	No	Yes	1	6	7
76	R:R:S140	R:R:V89	3.23	No	No	0	7	4
77	R:R:F91	R:R:L90	7.31	Yes	No	0	6	4
78	R:R:L90	R:R:S140	6.01	No	No	0	4	7
79	R:R:S136	R:R:T93	3.2	No	No	0	8	6
80	R:R:S181	R:R:T93	7.99	No	No	0	6	6
81	R:R:A94	R:R:W133	6.48	No	No	0	7	9
82	R:R:I96	R:R:P185	3.39	No	Yes	0	8	8
83	R:R:F244	R:R:I96	3.77	Yes	No	3	9	8
84	R:R:I96	R:R:W248	5.87	No	Yes	3	8	8
85	R:R:A132	R:R:M97	3.22	No	No	0	7	6
86	R:R:H98	R:R:W133	10.58	Yes	No	7	8	9
87	R:R:L99	R:R:N286	4.12	No	No	0	8	9
88	R:R:L99	R:R:Y290	4.69	No	Yes	0	8	9
89	R:R:C100	R:R:P185	3.77	No	Yes	0	7	8
90	R:R:C100	R:R:I188	4.91	No	No	0	7	6
91	R:R:C101	R:R:M128	3.24	No	No	6	6	5
92	R:R:I102	R:R:Y290	4.84	No	Yes	0	8	9
93	R:R:M189	R:R:S103	6.13	No	No	0	8	9
94	R:R:S103	R:R:T192	6.4	No	No	0	9	7
95	R:R:S103	R:R:Y193	7.63	No	Yes	0	9	9
96	R:R:D105	R:R:Y116	3.45	No	Yes	0	9	7
97	R:R:R106	R:R:Y290	5.14	No	Yes	0	9	9
98	R:R:Y107	R:R:Y108	3.97	No	No	0	8	4
99	R:R:I111	R:R:Y107	7.25	Yes	No	0	7	8
100	R:R:T192	R:R:Y107	8.74	No	No	0	7	8
101	R:R:K112	R:R:Y108	5.97	Yes	No	8	5	4
102	R:R:K119	R:R:Y108	10.75	No	No	8	5	4
103	R:R:A109	R:R:Y116	8.01	No	Yes	0	8	7
104	R:R:I110	R:R:I196	10.3	No	No	0	8	8
105	R:R:I111	R:R:K112	5.82	Yes	Yes	0	7	5
106	R:R:E199	R:R:I111	4.1	No	Yes	0	5	7
107	R:R:E115	R:R:K112	8.1	No	Yes	0	4	5
108	R:R:K112	R:R:K119	4.31	Yes	No	8	5	5
109	R:R:P117	R:R:Y116	4.17	No	Yes	0	3	7
110	R:R:I120	R:R:Y116	8.46	No	Yes	0	6	7
111	R:R:G122	R:R:T121	3.64	No	No	0	2	7
112	R:R:T121	R:R:T124	3.14	No	No	0	7	5
113	R:R:I139	R:R:S177	3.1	No	Yes	0	5	5
114	R:R:I139	R:R:V180	3.07	No	No	0	5	4
115	R:R:F141	R:R:F145	4.29	No	No	0	5	3
116	R:R:I142	R:R:P143	15.24	No	No	0	6	5
117	R:R:I144	R:R:Y149	13.3	No	Yes	1	5	5
118	R:R:L146	R:R:W148	15.94	No	No	0	4	5
119	R:R:T150	R:R:Y149	7.49	Yes	Yes	0	3	5
120	R:R:F167	R:R:Y149	3.09	Yes	Yes	1	4	5
121	R:R:Y149	R:R:Y173	4.96	Yes	Yes	0	5	7
122	R:R:H154	R:R:T150	8.21	Yes	Yes	0	2	3
123	R:R:L155	R:R:T150	10.32	No	Yes	0	3	3
124	R:R:N152	R:R:T151	5.85	No	No	9	2	3
125	R:R:E153	R:R:T151	4.23	No	No	9	1	3
126	R:R:E153	R:R:N152	6.57	No	No	9	1	2
127	R:R:H154	R:R:K158	17.03	Yes	Yes	2	2	4
128	R:R:H154	R:R:I166	3.98	Yes	No	2	2	4
129	R:R:H154	R:R:V168	8.3	Yes	No	2	2	3
130	R:R:C165	R:R:K158	4.85	No	Yes	2	9	4
131	R:R:I166	R:R:K158	4.36	No	Yes	2	4	4
132	R:R:E160	R:R:H161	7.39	No	No	0	4	5
133	R:R:I166	R:R:V168	6.14	No	No	2	4	3
134	R:R:F167	R:R:V169	3.93	Yes	Yes	1	4	3
135	R:R:F167	R:R:Y255	3.09	Yes	Yes	1	4	6
136	R:R:V169	R:R:Y173	7.57	Yes	Yes	0	3	7
137	R:R:V169	R:R:Y255	3.79	Yes	Yes	1	3	6
138	R:R:N170	R:R:P172	8.15	No	No	0	5	2
139	R:R:N170	R:R:Y173	3.49	No	Yes	0	5	7
140	R:R:K171	R:R:P172	3.35	No	No	0	3	2
141	R:R:I175	R:R:K171	7.27	No	No	0	5	3
142	R:R:K171	R:R:M260	12.96	No	No	0	3	4
143	R:R:S177	R:R:Y173	3.82	Yes	Yes	0	5	7
144	R:R:S178	R:R:Y255	6.36	No	Yes	0	5	6
145	R:R:S178	R:R:V256	3.23	No	No	0	5	6
146	R:R:S179	R:R:V180	3.23	No	No	0	4	4
147	R:R:F182	R:R:W183	8.02	Yes	No	0	8	4
148	R:R:C186	R:R:F182	12.57	No	Yes	3	6	8
149	R:R:F182	R:R:F244	6.43	Yes	Yes	3	8	9
150	R:R:F182	R:R:F252	24.65	Yes	No	0	8	7
151	R:R:I184	R:R:P185	3.39	No	Yes	0	5	8
152	R:R:C186	R:R:F244	4.19	No	Yes	3	6	9
153	R:R:F244	R:R:M189	8.71	Yes	No	0	9	8
154	R:R:F191	R:R:R195	9.62	No	Yes	0	3	5
155	R:R:L237	R:R:Y193	7.03	No	Yes	0	8	9
156	R:R:I240	R:R:Y193	4.84	No	Yes	0	8	9
157	R:R:Y193	R:R:Y290	3.97	Yes	Yes	0	9	9
158	R:R:T201	R:R:Y197	6.24	No	No	0	5	5
159	R:R:A234	R:R:Y197	5.34	No	No	0	6	5
160	R:R:E199	R:R:R202	15.12	No	No	0	5	4
161	R:R:I239	R:R:K235	4.36	No	No	0	7	6
162	R:R:F293	R:R:T236	15.56	Yes	No	0	7	8
163	R:R:G238	R:R:M241	3.49	No	No	0	5	8
164	R:R:F293	R:R:I239	3.77	Yes	No	0	7	7
165	R:R:F293	R:R:I240	5.02	Yes	No	0	7	8
166	R:R:G242	R:R:M241	3.49	No	No	0	5	8
167	R:R:F244	R:R:W248	4.01	Yes	Yes	3	9	8
168	R:R:I245	R:R:L249	4.28	No	Yes	0	5	6
169	R:R:C247	R:R:I278	3.27	No	No	0	9	7
170	R:R:C247	R:R:N282	6.3	No	Yes	0	9	9
171	R:R:F252	R:R:W248	6.01	No	Yes	0	7	8
172	R:R:N282	R:R:W248	9.04	Yes	Yes	0	9	8
173	R:R:L249	R:R:L253	5.54	Yes	No	0	6	5
174	R:R:F251	R:R:F276	5.36	No	No	1	6	5
175	R:R:I258	R:R:W254	14.09	No	No	0	3	4
176	R:R:V272	R:R:W254	11.03	No	No	0	4	4
177	R:R:L275	R:R:W254	3.42	No	No	0	5	4
178	R:R:I258	R:R:T259	4.56	No	No	0	3	3
179	R:R:L275	R:R:V271	4.47	No	No	0	5	4
180	R:R:F276	R:R:V272	5.24	No	No	0	5	4
181	R:R:W277	R:R:Y280	6.75	Yes	Yes	1	4	7
182	R:R:L281	R:R:L285	5.54	No	No	0	5	6
183	R:R:N282	R:R:N286	12.26	Yes	No	0	9	9
184	R:R:F293	R:R:I289	7.54	Yes	No	0	7	8
185	R:R:A291	R:R:F297	4.16	No	Yes	0	7	8
186	R:R:F293	R:R:Y292	7.22	Yes	No	0	7	5
187	R:R:R298	R:R:Y292	7.2	No	No	0	8	5
188	R:R:F297	R:R:N294	9.67	Yes	No	0	8	8
189	R:R:E303	R:R:Q306	6.37	No	No	0	4	4
190	R:R:I41	R:R:T43	3.04	No	No	0	7	8
191	R:R:K11	R:R:T69	3	No	No	0	5	4
192	R:R:L75	R:R:S71	3	No	No	0	2	4
193	R:R:L90	R:R:S136	3	No	No	0	4	8
194	R:R:L285	R:R:S284	3	No	No	0	6	7
195	R:R:L8	R:R:T12	2.95	No	No	0	4	6
196	R:R:L13	R:R:T17	2.95	No	No	0	5	4
197	R:R:L28	R:R:T304	2.95	No	No	0	6	4
198	R:R:A53	R:R:H98	2.93	No	Yes	0	8	8
199	R:R:I142	R:R:L146	2.85	No	No	0	6	4
200	R:R:E296	R:R:L39	2.65	No	Yes	0	6	8
201	R:R:F64	R:R:S67	2.64	No	No	0	4	4
202	R:R:F297	R:R:V29	2.62	Yes	No	0	8	9
203	R:R:F297	R:R:V33	2.62	Yes	No	0	8	7
204	R:R:R195	R:R:V198	2.62	Yes	No	0	5	4
205	R:R:F301	R:R:V288	2.62	No	No	0	7	6
206	R:R:V156	R:R:Y157	2.52	No	No	0	4	3
207	R:R:I111	R:R:R195	2.51	Yes	Yes	0	7	5
208	R:R:V68	R:R:W74	2.45	No	Yes	0	3	8
209	R:R:V68	R:R:W84	2.45	No	No	0	3	6
210	R:R:F182	R:R:L249	2.44	Yes	Yes	0	8	6
211	R:R:I18	R:R:W277	2.35	No	Yes	0	7	4
212	R:R:H37	R:R:R35	2.26	No	No	0	5	6
213	R:R:G72	R:R:S71	1.86	No	No	0	3	4
214	R:R:G137	R:R:S136	1.86	No	No	0	3	8
215	R:R:G137	R:R:S140	1.86	No	No	0	3	7
216	R:R:G122	R:R:V125	1.84	No	No	0	2	7
217	R:R:A22	R:R:A58	1.79	No	No	0	7	7
218	R:R:A200	R:R:A233	1.79	No	No	0	8	8
219	R:R:G25	R:R:L28	1.71	No	No	0	8	6
220	R:R:A300	R:R:S32	1.71	No	No	0	6	8
221	R:R:C100	R:R:V104	1.71	No	No	0	7	6
222	R:R:G147	R:R:L146	1.71	No	No	0	3	4
223	R:R:G238	R:R:L237	1.71	No	No	0	5	8
224	R:R:A58	R:R:V23	1.7	No	No	0	7	6
225	R:R:A51	R:R:V29	1.7	No	No	0	9	9
226	R:R:A51	R:R:V30	1.7	No	No	0	9	7
227	R:R:A174	R:R:V169	1.7	No	Yes	0	5	3
228	R:R:G279	R:R:N282	1.7	No	Yes	0	7	9
229	R:R:M97	R:R:P185	1.68	No	Yes	0	6	8
230	R:R:K112	R:R:P113	1.67	Yes	No	0	5	8
231	R:R:C131	R:R:I127	1.64	No	No	0	3	2
232	R:R:L249	R:R:P250	1.64	Yes	No	0	6	9
233	R:R:S21	R:R:S284	1.63	No	No	0	5	7
234	R:R:S20	R:R:V16	1.62	No	No	0	4	5
235	R:R:S32	R:R:V33	1.62	No	No	0	8	7
236	R:R:S135	R:R:V180	1.62	No	No	0	3	4
237	R:R:A243	R:R:I289	1.62	No	No	0	6	8
238	R:R:S32	R:R:T304	1.6	No	No	0	8	4
239	R:R:T130	R:R:V134	1.59	No	No	0	5	4
240	R:R:C186	R:R:L190	1.59	No	No	0	6	5
241	R:R:T150	R:R:T151	1.57	Yes	No	0	3	3
242	R:R:I70	R:R:S67	1.55	No	No	0	5	4
243	R:R:I176	R:R:S177	1.55	No	Yes	0	4	5
244	R:R:I176	R:R:S179	1.55	No	No	0	4	4
245	R:R:I258	R:R:S257	1.55	No	No	0	3	4
246	R:R:I34	R:R:V30	1.54	No	No	0	3	7
247	R:R:I289	R:R:V288	1.54	No	No	0	8	6
248	R:R:H161	R:R:P162	1.53	No	No	0	5	3
249	R:R:I19	R:R:T63	1.52	No	No	0	5	7
250	R:R:F24	R:R:G25	1.51	No	No	0	3	8
251	R:R:A307	R:R:E303	1.51	No	No	0	5	4
252	R:R:G72	R:R:R73	1.5	No	No	0	3	4
253	R:R:L59	R:R:V23	1.49	No	No	0	5	6
254	R:R:L274	R:R:V271	1.49	No	No	0	4	4
255	R:R:G147	R:R:Y149	1.45	No	Yes	0	3	5
256	R:R:K38	R:R:L39	1.41	No	Yes	0	5	8
257	R:R:L10	R:R:L13	1.38	No	No	0	5	5
258	R:R:E199	R:R:I110	1.37	No	No	0	5	8
259	R:R:H36	R:R:L39	1.29	No	Yes	0	5	8
260	R:R:I127	R:R:R123	1.25	No	No	0	2	4
261	R:R:F24	R:R:L27	1.22	No	No	0	3	3
262	R:R:L237	R:R:Y197	1.17	No	No	0	8	5
263	R:R:Q203	R:R:R202	1.17	No	No	0	6	4
264	R:R:E164	R:R:R73	1.16	No	No	0	4	4
265	R:R:H36	R:R:R35	1.13	No	No	0	5	6
266	R:R:H161	R:R:Y157	1.09	No	No	0	5	3
267	R:R:R195	R:R:W194	1	Yes	No	0	5	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	10.6156	9	1	0
2	R:R:L39	3.3975	4	0	8
3	R:R:F46	5.55667	6	6	7
4	R:R:D54	5.734	5	5	9
5	R:R:M62	7.025	4	0	7
6	R:R:W74	7.324	5	2	8
7	R:R:F91	8.7825	4	4	6
8	R:R:H98	7.1325	4	7	8
9	R:R:I111	4.92	4	0	7
10	R:R:K112	5.174	5	8	5
11	R:R:Y116	6.0225	4	0	7
12	R:R:Y149	6.77167	6	1	5
13	R:R:T150	6.8975	4	0	3
14	R:R:H154	9.38	4	2	2
15	R:R:K158	7.5775	4	2	4
16	R:R:F167	6.792	5	1	4
17	R:R:V169	4.2475	4	1	3
18	R:R:Y173	4.96	4	0	7
19	R:R:S177	3.1625	4	0	5
20	R:R:F182	10.822	5	3	8
21	R:R:P185	3.0575	4	0	8
22	R:R:Y193	5.8675	4	0	9
23	R:R:R195	3.9375	4	0	5
24	R:R:F244	5.422	5	3	9
25	R:R:W248	6.2325	4	3	8
26	R:R:L249	3.475	4	0	6
27	R:R:Y255	6.0275	4	1	6
28	R:R:W277	8.436	5	1	4
29	R:R:Y280	6.63667	6	1	7
30	R:R:N282	7.325	4	0	9
31	R:R:Y290	4.66	4	0	9
32	R:R:F293	7.822	5	0	7
33	R:R:F297	6.04667	6	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y280	92.299	5.44	Yes	Yes	1	0	7
2	R:R:W277	R:R:Y280	10.7032	6.75	Yes	Yes	1	4	7
3	R:R:M62	R:R:Y280	96.9779	14.37	Yes	Yes	0	7	7
4	R:R:A58	R:R:M62	12.6649	4.83	No	Yes	0	7	7
5	R:R:M62	R:R:S283	99.3108	3.07	Yes	No	0	7	9
6	R:R:D54	R:R:S283	99.5626	5.89	Yes	No	0	9	9
7	R:R:D54	R:R:L50	99.9602	8.14	Yes	No	0	9	9
8	R:R:H98	R:R:L50	100	3.86	Yes	No	0	8	9
9	R:R:H98	R:R:S49	98.4094	11.16	Yes	No	7	8	9
10	R:R:L129	R:R:S49	99.9867	7.51	No	No	0	7	9
11	R:R:F46	R:R:L129	99.8476	4.87	Yes	No	0	7	7
12	R:R:D105	R:R:F46	48.1609	3.58	No	Yes	0	9	7
13	R:R:D105	R:R:T43	42.309	7.23	No	No	0	9	8
14	R:R:I41	R:R:T43	41.0763	3.04	No	No	0	7	8
15	R:R:I41	R:R:N44	39.8171	8.5	No	No	0	7	8
16	R:R:F297	R:R:N44	26.6088	9.67	Yes	No	0	8	8
17	R:R:F297	R:R:V33	15.3092	2.62	Yes	No	0	8	7
18	R:R:S32	R:R:V33	12.4727	1.62	No	No	0	8	7
19	R:R:L39	R:R:N44	14.0102	8.24	Yes	No	0	8	8
20	R:R:F46	R:R:I102	85.9898	3.77	Yes	No	0	7	8
21	L:L:?1	R:R:V89	24.2958	16.58	Yes	No	0	0	4
22	R:R:S140	R:R:V89	22.8577	3.23	No	No	0	7	4
23	R:R:L90	R:R:S140	15.2495	6.01	No	No	0	4	7
24	L:L:?1	R:R:F167	56.1667	4.52	Yes	Yes	1	0	4
25	R:R:F167	R:R:N85	27.5035	19.33	Yes	No	0	4	4
26	R:R:N85	R:R:W84	26.2642	3.39	No	No	0	4	6
27	R:R:F64	R:R:W84	14.547	20.04	No	No	0	4	6
28	R:R:F64	R:R:S67	12.983	2.64	No	No	0	4	4
29	R:R:I70	R:R:S67	11.4057	1.55	No	No	0	5	4
30	R:R:V68	R:R:W84	12.0021	2.45	No	No	0	3	6
31	R:R:V68	R:R:W74	10.7164	2.45	No	Yes	0	3	8
32	R:R:F167	R:R:Y149	32.1691	3.09	Yes	Yes	1	4	5
33	R:R:T150	R:R:Y149	15.117	7.49	Yes	Yes	0	3	5
34	R:R:I102	R:R:Y290	85.3337	4.84	No	Yes	0	8	9
35	R:R:L99	R:R:Y290	19.3386	4.69	No	Yes	0	8	9
36	R:R:L99	R:R:N286	18.1523	4.12	No	No	0	8	9
37	R:R:N282	R:R:N286	16.9329	12.26	Yes	No	0	9	9
38	R:R:N282	R:R:W248	13.036	9.04	Yes	Yes	0	9	8
39	R:R:Y193	R:R:Y290	66.8368	3.97	Yes	Yes	0	9	9
40	R:R:S103	R:R:Y193	50.0497	7.63	No	Yes	0	9	9
41	R:R:M189	R:R:S103	26.6883	6.13	No	No	0	8	9
42	R:R:F244	R:R:M189	25.4357	8.71	Yes	No	0	9	8
43	R:R:F244	R:R:I96	11.8166	3.77	Yes	No	3	9	8
44	R:R:I96	R:R:P185	18.7753	3.39	No	Yes	0	8	8
45	R:R:S103	R:R:T192	28.9814	6.4	No	No	0	9	7
46	R:R:T192	R:R:Y107	27.6493	8.74	No	No	0	7	8
47	R:R:I111	R:R:Y107	19.0139	7.25	Yes	No	0	7	8
48	L:L:?1	R:R:S177	15.5809	4.18	Yes	Yes	0	0	5
49	R:R:L237	R:R:Y193	10.8026	7.03	No	Yes	0	8	9
50	R:R:I240	R:R:Y193	16.3364	4.84	No	Yes	0	8	9
51	R:R:F293	R:R:I240	15.0374	5.02	Yes	No	0	7	8
52	L:L:?1	R:R:F276	14.1891	7.91	Yes	No	1	0	5
53	R:R:F276	R:R:V272	12.7179	5.24	No	No	0	5	4
54	R:R:V272	R:R:W254	11.1671	11.03	No	No	0	4	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D88	17.62	1	Yes	No	0	6	0	1
L:L:?1	R:R:V89	16.58	1	Yes	No	0	4	0	1
L:L:?1	R:R:S92	6.96	1	Yes	No	0	6	0	1
L:L:?1	R:R:F167	4.52	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:S177	4.18	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F251	21.46	1	Yes	No	0	6	0	1
L:L:?1	R:R:Y255	10.87	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:F276	7.91	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y280	5.44	1	Yes	Yes	0	7	0	1
R:R:A61	R:R:D88	4.63	1	No	No	6	6	2	1
R:R:A61	R:R:Y280	4	1	No	Yes	6	7	2	1
R:R:M62	R:R:Y280	14.37	0	Yes	Yes	7	7	2	1
R:R:N65	R:R:W277	12.43	1	No	Yes	6	4	2	2
R:R:N65	R:R:Y280	5.81	1	No	Yes	6	7	2	1
R:R:F167	R:R:N85	19.33	1	Yes	No	4	4	1	2
R:R:D88	R:R:Y280	3.45	1	No	Yes	6	7	1	1
R:R:S140	R:R:V89	3.23	0	No	No	7	4	2	1
R:R:I139	R:R:S177	3.1	0	No	Yes	5	5	2	1
R:R:F167	R:R:Y149	3.09	1	Yes	Yes	4	5	1	2
R:R:Y149	R:R:Y173	4.96	1	Yes	Yes	5	7	2	2
R:R:F167	R:R:V169	3.93	1	Yes	Yes	4	3	1	2
R:R:F167	R:R:Y255	3.09	1	Yes	Yes	4	6	1	1
R:R:V169	R:R:Y173	7.57	1	Yes	Yes	3	7	2	2
R:R:V169	R:R:Y255	3.79	1	Yes	Yes	3	6	2	1
R:R:S177	R:R:Y173	3.82	0	Yes	Yes	5	7	1	2
R:R:S178	R:R:Y255	6.36	0	No	Yes	5	6	2	1
R:R:F251	R:R:F276	5.36	1	No	No	6	5	1	1
R:R:F276	R:R:V272	5.24	1	No	No	5	4	1	2
R:R:W277	R:R:Y280	6.75	1	Yes	Yes	4	7	2	1
R:R:I176	R:R:S177	1.55	0	No	Yes	4	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9M55_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.07
Number of Linked Nodes	246
Number of Links	267
Number of Hubs	33
Number of Links mediated by Hubs	130
Number of Communities	9
Number of Nodes involved in Communities	47
Number of Links involved in Communities	58

Path Summary
Number Of Nodes in MetaPath	55
Number Of Links MetaPath	54
Number of Shortest Paths	29382
Length Of Smallest Path	3
Average Path Length	14.6475
Length of Longest Path	33
Minimum Path Strength	1.21
Average Path Strength	6.15568
Maximum Path Strength	19.54
Minimum Path Correlation	0.7
Average Path Correlation	0.922005
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	45.3816
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.608
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	B7Q337
Sequence	>9M55_nogp_Chain_R L K L V L K T L A L V T I I S S A V F G N L L V V T S V I R H H K L R I T T N Y F I V S L A L A D T L V A L F A M T F N A S V T I S G R W L F N Q T V C D F W N S C D V L F S T A S I M H L C C I S V D R Y Y A I I K P L E Y P T K I T G R T V A I M L T C A W V S S G L I S F I P I F L G W Y T T N E H L V Y K V E H P D E C I F V V N K P Y A I I S S S V S F W I P C C I M L F T Y W R I Y V E A T R Q E K M L C K A A K T L G I I M G A F I L C W L P F F L W Y V S I T M L V V D L L F W I G Y L N S S L N P V I Y A Y F N R E F R Q A F K E T L Q A I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9M55	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	DPMF	-	chim(NtGi1-Gs)/β1/γ2	3.39	2025-12-17	10.1093/pnasnexus/pgaf376
	9M55 (No Gprot)	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	DPMF	-		3.39	2025-12-17	10.1093/pnasnexus/pgaf376
	9M57	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	Octopamine	-	chim(NtGi1-Gs)/β1/γ2	3.65	2025-12-17	10.1093/pnasnexus/pgaf376
	9M57 (No Gprot)	A	Amine	Adrenergic	Oct-Beta2	Ixodes scapularis	Octopamine	-		3.65	2025-12-17	10.1093/pnasnexus/pgaf376

2D representation of the interactions of this orthosteric/allosteric ligand.

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

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Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.