psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E23	R:R:Y93	3.37	No	Yes	0	1	7
2	R:R:E23	R:R:R302	4.65	No	Yes	0	1	8
3	R:R:P25	R:R:S24	5.34	No	No	0	5	6
4	R:R:A26	R:R:S24	3.42	No	No	0	4	6
5	R:R:I27	R:R:R302	8.77	No	Yes	0	4	8
6	L:L:?1	R:R:S28	8.98	Yes	No	0	0	7
7	R:R:M31	R:R:R302	6.2	No	Yes	1	8	8
8	R:R:M31	R:R:S305	3.07	No	No	1	8	8
9	L:L:?1	R:R:M31	6.34	Yes	No	1	0	8
10	R:R:F32	R:R:V36	3.93	No	No	0	8	7
11	R:R:F32	R:R:S86	9.25	No	Yes	0	8	8
12	R:R:G35	R:R:I309	7.05	No	No	0	9	9
13	R:R:L79	R:R:V36	2.98	Yes	No	0	8	7
14	R:R:T82	R:R:V36	3.17	No	No	0	8	7
15	R:R:D78	R:R:N39	4.04	Yes	No	3	9	9
16	R:R:L79	R:R:N39	5.49	Yes	No	0	8	9
17	R:R:N39	R:R:P312	6.52	No	Yes	3	9	9
18	R:R:L40	R:R:L79	6.92	No	Yes	0	5	8
19	R:R:L43	R:R:V75	5.96	No	No	0	8	9
20	R:R:L46	R:R:V71	5.96	No	No	0	9	8
21	R:R:L46	R:R:T72	7.37	No	No	0	9	5
22	R:R:L66	R:R:L70	5.54	No	Yes	0	6	7
23	R:R:F67	R:R:V71	7.87	No	No	0	8	8
24	R:R:F67	R:R:M130	3.73	No	No	2	8	9
25	R:R:F315	R:R:F67	4.29	Yes	No	2	9	8
26	R:R:L154	R:R:V69	2.98	No	Yes	0	5	7
27	R:R:L70	R:R:M126	4.24	Yes	No	0	7	8
28	R:R:L70	R:R:M130	5.65	Yes	No	0	7	9
29	R:R:E133	R:R:L70	5.3	No	Yes	0	9	7
30	R:R:E73	R:R:M126	4.06	No	No	0	7	8
31	R:R:E73	R:R:L157	19.88	No	No	0	7	7
32	R:R:D78	R:R:L74	5.43	Yes	Yes	0	9	9
33	R:R:L74	R:R:M126	4.24	Yes	No	0	9	8
34	R:R:L127	R:R:L74	4.15	No	Yes	0	8	9
35	R:R:F315	R:R:L74	3.65	Yes	Yes	0	9	9
36	R:R:P312	R:R:V75	7.07	Yes	No	0	9	9
37	R:R:F76	R:R:L80	4.87	No	No	0	6	5
38	R:R:F76	R:R:Y161	5.16	No	Yes	0	6	7
39	R:R:T77	R:R:Y161	7.49	No	Yes	0	9	7
40	R:R:D78	R:R:T123	4.34	Yes	No	0	9	8
41	R:R:D78	R:R:S308	5.89	Yes	No	0	9	8
42	R:R:D78	R:R:P312	3.22	Yes	Yes	3	9	9
43	R:R:C83	R:R:L79	3.17	No	Yes	0	7	8
44	R:R:F119	R:R:G81	10.54	No	No	0	8	9
45	R:R:S86	R:R:T82	3.2	Yes	No	1	8	8
46	L:L:?1	R:R:T82	8.82	Yes	No	1	0	8
47	R:R:L84	R:R:Y111	3.52	No	No	0	5	6
48	R:R:F112	R:R:I85	6.28	No	No	0	5	6
49	R:R:A115	R:R:I85	3.25	No	No	0	5	6
50	L:L:?1	R:R:I85	5.34	Yes	No	0	0	6
51	L:L:?1	R:R:S86	11.23	Yes	Yes	1	0	8
52	R:R:T185	R:R:V89	3.17	Yes	No	1	8	7
53	L:L:?1	R:R:V89	5.57	Yes	No	1	0	7
54	R:R:T185	R:R:Y93	6.24	Yes	Yes	1	8	7
55	L:L:?1	R:R:Y93	4.38	Yes	Yes	1	0	7
56	R:R:N96	R:R:V100	11.82	No	No	0	5	3
57	R:R:C109	R:R:C187	7.28	No	No	0	9	9
58	R:R:T110	R:R:Y178	6.24	No	No	0	4	6
59	R:R:F112	R:R:W186	3.01	No	Yes	0	5	7
60	R:R:A113	R:R:Y178	8.01	No	No	0	7	6
61	R:R:F114	R:R:Y178	5.16	No	No	0	7	6
62	R:R:F188	R:R:M116	3.73	Yes	No	0	8	7
63	L:L:?1	R:R:M116	9.51	Yes	No	0	0	7
64	R:R:C168	R:R:T117	3.38	No	Yes	0	8	7
65	R:R:F188	R:R:T117	3.89	Yes	Yes	1	8	7
66	R:R:I189	R:R:T117	3.04	Yes	Yes	1	6	7
67	R:R:T117	R:R:Y200	3.75	Yes	Yes	1	7	7
68	R:R:F118	R:R:F119	11.79	Yes	No	0	7	8
69	R:R:F118	R:R:Y161	6.19	Yes	Yes	0	7	7
70	R:R:F118	R:R:S164	6.61	Yes	No	0	7	7
71	R:R:F118	R:R:L165	4.87	Yes	No	0	7	4
72	R:R:S120	R:R:Y200	5.09	No	Yes	1	7	7
73	R:R:L204	R:R:S120	3	No	No	1	7	7
74	R:R:F167	R:R:L121	4.87	No	No	0	6	7
75	R:R:L121	R:R:Y200	7.03	No	Yes	0	7	7
76	R:R:L121	R:R:L203	4.15	No	No	0	7	5
77	L:L:?1	R:R:T123	5.51	Yes	No	0	0	8
78	R:R:L207	R:R:M124	4.24	No	No	0	7	7
79	L:L:?1	R:R:M124	3.17	Yes	No	0	0	7
80	R:R:I160	R:R:L125	8.56	No	No	0	6	6
81	R:R:L125	R:R:L207	5.54	No	No	0	6	7
82	R:R:F273	R:R:L127	3.65	Yes	No	0	8	8
83	R:R:D311	R:R:L127	9.5	No	No	0	9	8
84	R:R:F128	R:R:L132	4.87	No	No	0	6	6
85	R:R:F128	R:R:S210	3.96	No	No	0	6	5
86	R:R:F315	R:R:M130	6.22	Yes	No	2	9	9
87	R:R:A131	R:R:V211	5.09	No	No	0	9	8
88	R:R:E133	R:R:Y144	5.61	No	No	0	9	8
89	R:R:N215	R:R:R134	3.62	No	Yes	2	9	9
90	R:R:R134	R:R:V218	3.92	Yes	Yes	2	9	9
91	R:R:L266	R:R:R134	6.07	Yes	Yes	2	8	9
92	R:R:M269	R:R:R134	4.96	Yes	Yes	2	9	9
93	R:R:F315	R:R:R134	3.21	Yes	Yes	2	9	9
94	R:R:L136	R:R:Y135	3.52	No	Yes	0	5	6
95	R:R:H140	R:R:Y135	9.8	No	Yes	0	5	6
96	R:R:C214	R:R:Y135	6.72	No	Yes	0	7	6
97	R:R:S217	R:R:Y135	6.36	No	Yes	0	6	6
98	R:R:F143	R:R:L136	3.65	No	No	0	4	5
99	R:R:I138	R:R:S137	3.1	No	No	0	8	9
100	R:R:S137	R:R:Y144	7.63	No	No	0	9	8
101	R:R:I138	R:R:V218	4.61	No	Yes	0	8	9
102	R:R:G139	R:R:N221	3.39	No	No	0	7	6
103	R:R:F143	R:R:R147	8.55	No	No	0	4	4
104	R:R:V148	R:R:Y144	13.88	No	No	0	5	8
105	R:R:R146	R:R:R147	7.46	No	No	0	5	4
106	R:R:L157	R:R:P158	4.93	No	No	0	7	3
107	R:R:L157	R:R:Y161	12.89	No	Yes	0	7	7
108	R:R:F167	R:R:Y196	8.25	No	Yes	0	6	6
109	R:R:F167	R:R:L199	4.87	No	No	0	6	5
110	R:R:L170	R:R:P171	4.93	No	No	0	7	9
111	R:R:L170	R:R:Y175	7.03	No	No	0	7	4
112	R:R:P171	R:R:Y196	6.95	No	Yes	0	9	6
113	R:R:L173	R:R:Y175	3.52	No	No	0	3	4
114	R:R:Q177	R:R:R190	10.51	No	No	0	3	5
115	R:R:R190	R:R:V179	5.23	No	No	0	5	4
116	R:R:W186	R:R:Y181	27.01	Yes	No	1	7	8
117	R:R:F188	R:R:Y181	3.09	Yes	No	1	8	8
118	R:R:C182	R:R:P183	3.77	No	No	0	3	8
119	R:R:C182	R:R:K295	3.23	No	No	0	3	1
120	R:R:P183	R:R:W186	8.11	No	Yes	1	8	7
121	R:R:L298	R:R:P183	6.57	Yes	No	1	6	8
122	L:L:?1	R:R:T185	3.31	Yes	Yes	1	0	8
123	R:R:F188	R:R:W186	3.01	Yes	Yes	1	8	7
124	R:R:L298	R:R:W186	6.83	Yes	Yes	1	6	7
125	R:R:L301	R:R:W186	4.56	No	Yes	0	7	7
126	R:R:F188	R:R:I189	8.79	Yes	Yes	1	8	6
127	R:R:F188	R:R:Y200	4.13	Yes	Yes	1	8	7
128	R:R:F188	R:R:F280	6.43	Yes	Yes	1	8	8
129	R:R:I189	R:R:Y196	7.25	Yes	Yes	0	6	6
130	R:R:I189	R:R:L197	4.28	Yes	No	0	6	7
131	R:R:R190	R:R:R193	9.6	No	No	0	5	5
132	R:R:G192	R:R:H191	3.18	No	Yes	5	3	6
133	R:R:H191	R:R:R193	4.51	Yes	No	5	6	5
134	R:R:H191	R:R:N287	3.83	Yes	No	0	6	6
135	R:R:E288	R:R:H191	14.77	No	Yes	0	5	6
136	R:R:G192	R:R:R193	3	No	No	5	3	5
137	R:R:Q198	R:R:Y285	4.51	No	No	0	4	5
138	R:R:L204	R:R:Y200	9.38	No	Yes	1	7	7
139	R:R:F280	R:R:Y200	5.16	Yes	Yes	1	8	7
140	R:R:A201	R:R:Y285	5.34	No	No	0	7	5
141	R:R:L204	R:R:T281	4.42	No	No	0	7	7
142	R:R:F273	R:R:I208	5.02	Yes	No	4	8	8
143	R:R:I208	R:R:S277	3.1	No	Yes	4	8	9
144	R:R:F273	R:R:V211	13.11	Yes	No	0	8	8
145	R:R:A274	R:R:L212	3.15	No	No	0	6	7
146	R:R:L266	R:R:N215	5.49	Yes	No	2	8	9
147	R:R:N215	R:R:T270	11.7	No	No	0	9	8
148	R:R:F216	R:R:T270	3.89	No	No	0	5	8
149	R:R:L222	R:R:V218	2.98	No	Yes	0	8	9
150	R:R:L266	R:R:V218	2.98	Yes	Yes	2	8	9
151	R:R:I219	R:R:L266	8.56	No	Yes	0	7	8
152	R:R:L220	R:R:R224	7.29	No	No	0	3	5
153	R:R:L222	R:R:L263	4.15	No	No	0	8	7
154	R:R:I223	R:R:L263	5.71	No	No	0	5	7
155	R:R:M225	R:R:R228	3.72	No	No	0	7	5
156	R:R:H226	R:R:R230	12.41	No	No	0	5	2
157	R:R:E259	R:R:H226	14.77	No	No	0	8	5
158	R:R:E258	R:R:R324	4.65	No	No	0	6	5
159	R:R:D261	R:R:L323	4.07	Yes	No	0	8	7
160	R:R:D261	R:R:R324	10.72	Yes	No	6	8	5
161	R:R:D261	R:R:R327	17.87	Yes	No	6	8	3
162	R:R:H262	R:R:P320	9.15	No	Yes	0	8	7
163	R:R:I264	R:R:L323	7.14	No	No	0	6	7
164	R:R:L265	R:R:M269	4.24	No	Yes	0	8	9
165	R:R:L265	R:R:P320	3.28	No	Yes	0	8	7
166	R:R:M269	R:R:V314	4.56	Yes	Yes	2	9	8
167	R:R:F315	R:R:M269	7.46	Yes	Yes	2	9	9
168	R:R:F273	R:R:S277	3.96	Yes	Yes	4	8	9
169	R:R:L304	R:R:S277	3	No	Yes	0	8	9
170	R:R:N307	R:R:S277	4.47	No	Yes	0	9	9
171	R:R:L278	R:R:T281	4.42	No	No	0	6	7
172	R:R:F303	R:R:P279	7.22	No	No	0	6	9
173	R:R:F280	R:R:L301	7.31	Yes	No	0	8	7
174	R:R:F280	R:R:L304	7.31	Yes	No	0	8	8
175	R:R:F283	R:R:S291	6.61	Yes	No	1	4	1
176	R:R:F283	R:R:W296	6.01	Yes	No	0	4	3
177	R:R:D297	R:R:F283	4.78	No	Yes	1	6	4
178	R:R:A300	R:R:F283	5.55	No	Yes	0	7	4
179	R:R:M286	R:R:S291	3.07	No	No	0	4	1
180	R:R:N287	R:R:T289	7.31	No	No	0	6	3
181	R:R:E288	R:R:R292	11.63	No	No	0	5	1
182	R:R:S290	R:R:T289	3.2	No	No	0	2	3
183	R:R:D297	R:R:S291	4.42	No	No	1	6	1
184	R:R:E294	R:R:W296	17.45	No	No	0	3	3
185	R:R:L298	R:R:R302	8.5	Yes	Yes	1	6	8
186	L:L:?1	R:R:L298	8.28	Yes	Yes	1	0	6
187	R:R:Q299	R:R:R302	8.18	No	Yes	0	4	8
188	L:L:?1	R:R:R302	7.27	Yes	Yes	1	0	8
189	R:R:F303	R:R:I306	5.02	No	No	0	6	4
190	R:R:I309	R:R:S305	3.1	No	No	0	9	8
191	L:L:?1	R:R:S305	12.35	Yes	No	1	0	8
192	R:R:D311	R:R:N307	6.73	No	No	0	9	9
193	L:L:?1	R:R:N307	7.19	Yes	No	0	0	9
194	L:L:?1	R:R:S308	6.74	Yes	No	0	0	8
195	R:R:I310	R:R:V314	3.07	No	Yes	0	7	8
196	R:R:D311	R:R:F315	4.78	No	Yes	0	9	9
197	R:R:I317	R:R:W313	11.74	No	No	0	8	6
198	R:R:F315	R:R:V314	3.93	Yes	Yes	2	9	8
199	R:R:P320	R:R:P321	5.84	Yes	No	0	7	7
200	R:R:R324	R:R:R327	21.32	No	No	6	5	3
201	R:R:L325	R:R:S328	3	No	No	0	5	4
202	R:R:L205	R:R:T281	2.95	No	No	0	6	7
203	R:R:I306	R:R:I310	2.94	No	No	0	4	7
204	R:R:P320	R:R:R319	2.88	Yes	No	0	7	9
205	R:R:E73	R:R:V69	2.85	No	Yes	0	7	7
206	R:R:I208	R:R:L212	2.85	No	No	0	8	7
207	R:R:Q97	R:R:T98	2.83	No	No	0	3	4
208	R:R:L222	R:R:M225	2.83	No	No	0	8	7
209	R:R:G38	R:R:W313	2.81	No	No	0	9	6
210	R:R:C168	R:R:F114	2.79	No	No	0	8	7
211	R:R:C182	R:R:R292	2.79	No	No	0	3	1
212	R:R:L132	R:R:L136	2.77	No	No	0	6	5
213	R:R:A122	R:R:Y161	2.67	No	Yes	0	7	7
214	R:R:L99	R:R:Q97	2.66	No	No	0	4	3
215	R:R:R150	R:R:S65	2.64	No	No	0	4	8
216	R:R:R107	R:R:S106	2.64	No	No	0	2	2
217	R:R:R150	R:R:V69	2.62	No	Yes	0	4	7
218	R:R:F128	R:R:V211	2.62	No	No	0	6	8
219	R:R:R327	R:R:T260	2.59	No	No	0	3	5
220	R:R:T194	R:R:Y196	2.5	No	Yes	0	3	6
221	R:R:F32	R:R:L90	2.44	No	No	0	8	7
222	R:R:F119	R:R:L84	2.44	No	No	0	8	5
223	R:R:N221	R:R:R224	2.41	No	No	0	6	5
224	R:R:L318	R:R:W313	2.28	No	No	0	6	6
225	R:R:D297	R:R:W186	2.23	No	Yes	1	6	7
226	R:R:G152	R:R:G153	2.11	No	No	0	5	7
227	R:R:G176	R:R:P171	2.03	No	No	0	8	9
228	R:R:A34	R:R:G35	1.95	No	No	0	6	9
229	R:R:A101	R:R:G184	1.95	No	No	0	3	5
230	R:R:A42	R:R:P312	1.87	No	Yes	0	9	9
231	R:R:A103	R:R:P104	1.87	No	No	0	5	3
232	R:R:G153	R:R:V69	1.84	No	Yes	0	7	7
233	R:R:G153	R:R:V156	1.84	No	No	0	7	4
234	R:R:A113	R:R:C187	1.81	No	No	0	7	9
235	R:R:A316	R:R:A42	1.79	No	No	0	9	9
236	R:R:A103	R:R:A108	1.79	No	No	0	5	5
237	R:R:A201	R:R:A284	1.79	No	No	0	7	5
238	R:R:P87	R:R:S86	1.78	No	Yes	0	7	8
239	R:R:P104	R:R:V100	1.77	No	No	0	3	3
240	R:R:G38	R:R:I41	1.76	No	No	0	9	5
241	R:R:C276	R:R:S277	1.72	No	Yes	0	9	9
242	R:R:A34	R:R:S33	1.71	No	No	0	6	5
243	R:R:G38	R:R:L37	1.71	No	No	0	9	5
244	R:R:C276	R:R:V275	1.71	No	No	0	9	5
245	R:R:A129	R:R:V156	1.7	No	No	0	7	4
246	R:R:S29	R:R:V30	1.62	No	No	0	4	5
247	R:R:S328	R:R:V329	1.62	No	No	0	4	4
248	R:R:D261	R:R:P320	1.61	Yes	Yes	0	8	7
249	R:R:S92	R:R:T185	1.6	No	Yes	0	5	8
250	R:R:V159	R:R:V163	1.6	No	No	0	3	3
251	R:R:G139	R:R:H140	1.59	No	No	0	7	5
252	R:R:A108	R:R:L102	1.58	No	No	0	5	3
253	R:R:A284	R:R:L197	1.58	No	No	0	5	7
254	R:R:I268	R:R:V314	1.54	No	Yes	0	5	8
255	R:R:H140	R:R:P141	1.53	No	No	0	5	9
256	R:R:C187	R:R:Q180	1.53	No	No	0	9	4
257	R:R:A101	R:R:Q180	1.52	No	No	0	3	4
258	R:R:I268	R:R:T272	1.52	No	No	0	5	7
259	R:R:I271	R:R:T272	1.52	No	No	0	6	7
260	R:R:A108	R:R:E105	1.51	No	No	0	5	4
261	R:R:A257	R:R:E259	1.51	No	No	0	5	8
262	R:R:L37	R:R:S33	1.5	No	No	0	5	5
263	R:R:L125	R:R:V163	1.49	No	No	0	6	3
264	R:R:L199	R:R:T202	1.47	No	No	0	5	4
265	R:R:E259	R:R:S229	1.44	No	No	0	8	4
266	R:R:I41	R:R:L45	1.43	No	No	0	5	7
267	R:R:L325	R:R:M326	1.41	No	No	0	5	4
268	R:R:P25	R:R:Y93	1.39	No	Yes	0	5	7
269	R:R:L99	R:R:N96	1.37	No	No	0	4	5
270	R:R:H226	R:R:T260	1.37	No	No	0	5	5
271	R:R:F112	R:R:V88	1.31	No	No	0	5	5
272	R:R:R319	R:R:V322	1.31	No	No	0	9	7
273	R:R:R107	R:R:T110	1.29	No	No	0	2	4
274	R:R:F283	R:R:I282	1.26	Yes	No	0	4	6
275	R:R:L45	R:R:R48	1.21	No	No	0	7	5
276	R:R:N96	R:R:R95	1.21	No	No	0	5	4
277	R:R:R227	R:R:R230	1.07	No	No	0	5	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V69	2.5725	4	0	7
2	R:R:L70	5.1825	4	0	7
3	R:R:L74	4.3675	4	0	9
4	R:R:D78	4.584	5	3	9
5	R:R:L79	4.64	4	0	8
6	R:R:S86	6.365	4	1	8
7	R:R:Y93	3.845	4	1	7
8	R:R:T117	3.515	4	1	7
9	R:R:F118	7.365	4	0	7
10	R:R:R134	4.356	5	2	9
11	R:R:Y135	6.6	4	0	6
12	R:R:Y161	6.88	5	0	7
13	R:R:T185	3.58	4	1	8
14	R:R:W186	7.82286	7	1	7
15	R:R:F188	4.72429	7	1	8
16	R:R:I189	5.84	4	1	6
17	R:R:H191	6.5725	4	5	6
18	R:R:Y196	6.2375	4	0	6
19	R:R:Y200	5.75667	6	1	7
20	R:R:V218	3.6225	4	2	9
21	R:R:D261	8.5675	4	6	8
22	R:R:L266	5.775	4	2	8
23	R:R:M269	5.305	4	2	9
24	R:R:F273	6.435	4	4	8
25	R:R:S277	3.25	5	4	9
26	R:R:F280	6.5525	4	1	8
27	R:R:F283	4.842	5	1	4
28	R:R:L298	7.545	4	1	6
29	R:R:R302	7.26167	6	1	8
30	R:R:P312	4.67	4	3	9
31	R:R:V314	3.275	4	2	8
32	R:R:F315	4.79143	7	2	9
33	R:R:P320	4.552	5	0	7
34	L:L:?1	7.12437	16	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y93	13.697	4.38	Yes	Yes	1	0	7
2	L:L:?1	R:R:S305	36.5872	12.35	Yes	No	1	0	8
3	L:L:?1	R:R:S86	11.3577	11.23	Yes	Yes	1	0	8
4	R:R:I309	R:R:S305	34.5103	3.1	No	No	0	9	8
5	R:R:G35	R:R:I309	31.7118	7.05	No	No	0	9	9
6	R:R:D78	R:R:T123	45.868	4.34	Yes	No	0	9	8
7	L:L:?1	R:R:T123	45.9882	5.51	Yes	No	0	0	8
8	R:R:D78	R:R:S308	45.868	5.89	Yes	No	0	9	8
9	L:L:?1	R:R:S308	46.2287	6.74	Yes	No	0	0	8
10	R:R:D78	R:R:P312	18.7363	3.22	Yes	Yes	3	9	9
11	L:L:?1	R:R:N307	85.7018	7.19	Yes	No	0	0	9
12	R:R:D311	R:R:N307	76.4757	6.73	No	No	0	9	9
13	R:R:D311	R:R:F315	86.4342	4.78	No	Yes	0	9	9
14	R:R:F315	R:R:F67	10.9969	4.29	Yes	No	2	9	8
15	R:R:D78	R:R:L74	86.8933	5.43	Yes	Yes	0	9	9
16	R:R:L74	R:R:M126	100	4.24	Yes	No	0	9	8
17	R:R:L70	R:R:M126	17.7088	4.24	Yes	No	0	7	8
18	R:R:F315	R:R:M130	10.8986	6.22	Yes	No	2	9	9
19	R:R:L70	R:R:M130	10.3411	5.65	Yes	No	0	7	9
20	R:R:E73	R:R:M126	85.0022	4.06	No	No	0	7	8
21	R:R:E73	R:R:V69	31.2965	2.85	No	Yes	0	7	7
22	R:R:E133	R:R:L70	15.0197	5.3	No	Yes	0	9	7
23	R:R:E73	R:R:L157	52.6345	19.88	No	No	0	7	7
24	R:R:D311	R:R:L127	13.85	9.5	No	No	0	9	8
25	R:R:L157	R:R:Y161	45.2011	12.89	No	Yes	0	7	7
26	R:R:F118	R:R:Y161	26.2352	6.19	Yes	Yes	0	7	7
27	R:R:F118	R:R:F119	14.5934	11.79	Yes	No	0	7	8
28	R:R:A113	R:R:C187	16.714	1.81	No	No	0	7	9
29	R:R:A113	R:R:Y178	19.9934	8.01	No	No	0	7	6
30	R:R:F114	R:R:Y178	32.3568	5.16	No	No	0	7	6
31	R:R:C168	R:R:F114	35.516	2.79	No	No	0	8	7
32	R:R:C168	R:R:T117	38.0958	3.38	No	Yes	0	8	7
33	R:R:F188	R:R:T117	33.2641	3.89	Yes	Yes	1	8	7
34	R:R:F188	R:R:M116	79.0009	3.73	Yes	No	0	8	7
35	L:L:?1	R:R:M116	80.7936	9.51	Yes	No	0	0	7
36	R:R:F188	R:R:W186	16.4626	3.01	Yes	Yes	1	8	7
37	R:R:L298	R:R:W186	24.6283	6.83	Yes	Yes	1	6	7
38	R:R:F188	R:R:I189	40.1946	8.79	Yes	Yes	1	8	6
39	R:R:F188	R:R:Y200	25.0437	4.13	Yes	Yes	1	8	7
40	R:R:L204	R:R:Y200	16.4735	9.38	No	Yes	1	7	7
41	R:R:I189	R:R:Y196	26.8693	7.25	Yes	Yes	0	6	6
42	R:R:L121	R:R:Y200	18.5396	7.03	No	Yes	0	7	7
43	R:R:F167	R:R:L121	11.3139	4.87	No	No	0	6	7
44	L:L:?1	R:R:M124	16.9327	3.17	Yes	No	0	0	7
45	R:R:L207	R:R:M124	14.2873	4.24	No	No	0	7	7
46	R:R:L125	R:R:L207	11.3795	5.54	No	No	0	6	7
47	R:R:N307	R:R:S277	32.3021	4.47	No	Yes	0	9	9
48	R:R:F273	R:R:S277	36.5435	3.96	Yes	Yes	4	8	9
49	R:R:F273	R:R:V211	56.5479	13.11	Yes	No	0	8	8
50	R:R:F128	R:R:V211	50.4919	2.62	No	No	0	6	8
51	R:R:F128	R:R:L132	44.3485	4.87	No	No	0	6	6
52	R:R:E133	R:R:Y144	10.4722	5.61	No	No	0	9	8
53	R:R:F315	R:R:R134	33.8981	3.21	Yes	Yes	2	9	9
54	R:R:R134	R:R:V218	23.1745	3.92	Yes	Yes	2	9	9
55	R:R:F315	R:R:M269	48.0324	7.46	Yes	Yes	2	9	9
56	R:R:L132	R:R:L136	41.244	2.77	No	No	0	6	5
57	R:R:L136	R:R:Y135	29.1758	3.52	No	Yes	0	5	6
58	R:R:H140	R:R:Y135	19.4687	9.8	No	Yes	0	5	6
59	R:R:F143	R:R:L136	10.0896	3.65	No	No	0	4	5
60	R:R:G139	R:R:H140	12.8881	1.59	No	No	0	7	5
61	R:R:F167	R:R:L199	12.7241	4.87	No	No	0	6	5
62	R:R:P171	R:R:Y196	15.0415	6.95	No	Yes	0	9	6
63	R:R:L298	R:R:P183	30.7936	6.57	Yes	No	1	6	8
64	R:R:C182	R:R:P183	37.7897	3.77	No	No	0	3	8
65	R:R:C182	R:R:R292	32.2147	2.79	No	No	0	3	1
66	R:R:E288	R:R:R292	29.3944	11.63	No	No	0	5	1
67	R:R:E288	R:R:H191	26.5523	14.77	No	Yes	0	5	6
68	R:R:H191	R:R:R193	11.9698	4.51	Yes	No	5	6	5
69	R:R:F188	R:R:F280	12.2213	6.43	Yes	Yes	1	8	8
70	R:R:I189	R:R:L197	14.9213	4.28	Yes	No	0	6	7
71	R:R:A284	R:R:L197	12.4508	1.58	No	No	0	5	7
72	R:R:L204	R:R:T281	12.418	4.42	No	No	0	7	7
73	R:R:L222	R:R:V218	14.7792	2.98	No	Yes	0	8	9
74	R:R:L265	R:R:M269	50.9292	4.24	No	Yes	0	8	9
75	R:R:L265	R:R:P320	48.3384	3.28	No	Yes	0	8	7
76	R:R:D261	R:R:P320	35.4613	1.61	Yes	Yes	0	8	7
77	R:R:D261	R:R:R327	22.2453	17.87	Yes	No	6	8	3
78	R:R:R327	R:R:T260	19.9825	2.59	No	No	0	3	5
79	R:R:H226	R:R:T260	17.1404	1.37	No	No	0	5	5
80	R:R:F315	R:R:V314	20.9663	3.93	Yes	Yes	2	9	8
81	R:R:L304	R:R:S277	33.7669	3	No	Yes	0	8	9
82	R:R:I310	R:R:V314	12.3196	3.07	No	Yes	0	7	8
83	R:R:D297	R:R:W186	26.9458	2.23	No	Yes	1	6	7
84	R:R:D297	R:R:F283	16.8124	4.78	No	Yes	1	6	4
85	R:R:A34	R:R:G35	28.8916	1.95	No	No	0	6	9
86	R:R:A34	R:R:S33	26.0494	1.71	No	No	0	6	5
87	R:R:L37	R:R:S33	23.1854	1.5	No	No	0	5	5
88	R:R:G38	R:R:L37	20.2995	1.71	No	No	0	9	5
89	R:R:G153	R:R:V69	15.8177	1.84	No	Yes	0	7	7
90	R:R:C187	R:R:Q180	10.0896	1.53	No	No	0	9	4
91	L:L:?1	R:R:L298	53.8588	8.28	Yes	Yes	1	0	6
92	R:R:F315	R:R:L74	31.6681	3.65	Yes	Yes	0	9	9
93	R:R:L127	R:R:L74	29.0665	4.15	No	Yes	0	8	9
94	R:R:F273	R:R:L127	39.8666	3.65	Yes	No	0	8	8
95	R:R:F280	R:R:L304	32.969	7.31	Yes	No	0	8	8
96	R:R:F280	R:R:Y200	17.523	5.16	Yes	Yes	1	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:E23	R:R:Y93	3.37	0	No	Yes	1	7	2	1
R:R:E23	R:R:R302	4.65	0	No	Yes	1	8	2	1
R:R:I27	R:R:R302	8.77	0	No	Yes	4	8	2	1
L:L:?1	R:R:S28	8.98	1	Yes	No	0	7	0	1
R:R:M31	R:R:R302	6.2	1	No	Yes	8	8	1	1
R:R:M31	R:R:S305	3.07	1	No	No	8	8	1	1
L:L:?1	R:R:M31	6.34	1	Yes	No	0	8	0	1
R:R:F32	R:R:V36	3.93	0	No	No	8	7	2	2
R:R:F32	R:R:S86	9.25	0	No	Yes	8	8	2	1
R:R:T82	R:R:V36	3.17	1	No	No	8	7	1	2
R:R:D78	R:R:T123	4.34	3	Yes	No	9	8	2	1
R:R:D78	R:R:S308	5.89	3	Yes	No	9	8	2	1
R:R:S86	R:R:T82	3.2	1	Yes	No	8	8	1	1
L:L:?1	R:R:T82	8.82	1	Yes	No	0	8	0	1
R:R:F112	R:R:I85	6.28	0	No	No	5	6	2	1
R:R:A115	R:R:I85	3.25	0	No	No	5	6	2	1
L:L:?1	R:R:I85	5.34	1	Yes	No	0	6	0	1
L:L:?1	R:R:S86	11.23	1	Yes	Yes	0	8	0	1
R:R:T185	R:R:V89	3.17	1	Yes	No	8	7	1	1
L:L:?1	R:R:V89	5.57	1	Yes	No	0	7	0	1
R:R:T185	R:R:Y93	6.24	1	Yes	Yes	8	7	1	1
L:L:?1	R:R:Y93	4.38	1	Yes	Yes	0	7	0	1
R:R:F112	R:R:W186	3.01	0	No	Yes	5	7	2	2
R:R:F188	R:R:M116	3.73	1	Yes	No	8	7	2	1
L:L:?1	R:R:M116	9.51	1	Yes	No	0	7	0	1
L:L:?1	R:R:T123	5.51	1	Yes	No	0	8	0	1
R:R:L207	R:R:M124	4.24	0	No	No	7	7	2	1
L:L:?1	R:R:M124	3.17	1	Yes	No	0	7	0	1
R:R:P183	R:R:W186	8.11	1	No	Yes	8	7	2	2
R:R:L298	R:R:P183	6.57	1	Yes	No	6	8	1	2
L:L:?1	R:R:T185	3.31	1	Yes	Yes	0	8	0	1
R:R:F188	R:R:W186	3.01	1	Yes	Yes	8	7	2	2
R:R:L298	R:R:W186	6.83	1	Yes	Yes	6	7	1	2
R:R:N307	R:R:S277	4.47	0	No	Yes	9	9	1	2
R:R:L298	R:R:R302	8.5	1	Yes	Yes	6	8	1	1
L:L:?1	R:R:L298	8.28	1	Yes	Yes	0	6	0	1
R:R:Q299	R:R:R302	8.18	0	No	Yes	4	8	2	1
L:L:?1	R:R:R302	7.27	1	Yes	Yes	0	8	0	1
R:R:I309	R:R:S305	3.1	0	No	No	9	8	2	1
L:L:?1	R:R:S305	12.35	1	Yes	No	0	8	0	1
R:R:D311	R:R:N307	6.73	0	No	No	9	9	2	1
L:L:?1	R:R:N307	7.19	1	Yes	No	0	9	0	1
L:L:?1	R:R:S308	6.74	1	Yes	No	0	8	0	1
R:R:P87	R:R:S86	1.78	0	No	Yes	7	8	2	1
R:R:S92	R:R:T185	1.6	0	No	Yes	5	8	2	1
R:R:P25	R:R:Y93	1.39	0	No	Yes	5	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7CX2_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.98
Number of Linked Nodes	245
Number of Links	277
Number of Hubs	34
Number of Links mediated by Hubs	136
Number of Communities	6
Number of Nodes involved in Communities	44
Number of Links involved in Communities	60

Path Summary
Number Of Nodes in MetaPath	97
Number Of Links MetaPath	96
Number of Shortest Paths	34444
Length Of Smallest Path	3
Average Path Length	10.9944
Length of Longest Path	24
Minimum Path Strength	1.29
Average Path Strength	5.56241
Maximum Path Strength	17.56
Minimum Path Correlation	0.7
Average Path Correlation	0.917101
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	51.8946
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.2832
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • response to ketone • response to lipid • response to hormone • response to steroid hormone • response to chemical • response to endogenous stimulus • response to progesterone • response to oxygen-containing compound • cell population proliferation • regulation of cell population proliferation • defense response • response to stress • inflammatory response • biological process involved in interspecies interaction between organisms • response to other organism • response to external stimulus • response to external biotic stimulus • response to nematode • response to biotic stimulus • response to lipopolysaccharide • response to bacterium • response to molecule of bacterial origin • response to prostaglandin • response to alcohol • cellular response to prostaglandin stimulus • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cell periphery • cellular anatomical structure • plasma membrane • membrane • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to nitrogen compound • response to peptide hormone • cellular response to peptide hormone stimulus • response to nitrogen compound • response to glucagon • cellular response to glucagon stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	P2E
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	P2E
Name	Dinoprostone
Synonyms	Dinoprostona
Identifier
Formula	C20 H32 O5
Molecular Weight	352.465
SMILES
PubChem	5280360
Formal Charge	0
Total Atoms	57
Total Chiral Atoms	4
Total Bonds	57
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P43116
Sequence	>7CX2_nogp_Chain_R E S P A I S S V M F S A G V L G N L I A L A L L A R S L F H V L V T E L V F T D L L G T C L I S P V V L A S Y A R N Q T L V A L A P E S R A C T Y F A F A M T F F S L A T M L M L F A M A L E R Y L S I G H P Y F Y Q R R V S R S G G L A V L P V I Y A V S L L F C S L P L L D Y G Q Y V Q Y C P G T W C F I R H G R T A Y L Q L Y A T L L L L L I V S V L A C N F S V I L N L I R M H R R S R A E E T D H L I L L A I M T I T F A V C S L P F T I F A Y M N E T S S R K E K W D L Q A L R F L S I N S I I D P W V F A I L R P P V L R L M R S V L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7CX2	A	Lipid	Prostanoid	EP₂	Homo sapiens	PGE2	-	Gs/β1/γ2	2.8	2021-05-05	doi.org/10.1126/sciadv.abf1268
	7CX2 (No Gprot)	A	Lipid	Prostanoid	EP₂	Homo sapiens	PGE2	-		2.8	2021-05-05	doi.org/10.1126/sciadv.abf1268
	7CX3	A	Lipid	Prostanoid	EP₂	Homo sapiens	Taprenepag	-	Gs/β1/γ2	2.8	2021-05-05	doi.org/10.1126/sciadv.abf1268
	7CX3 (No Gprot)	A	Lipid	Prostanoid	EP₂	Homo sapiens	Taprenepag	-		2.8	2021-05-05	doi.org/10.1126/sciadv.abf1268
	7CX4	A	Lipid	Prostanoid	EP₂	Homo sapiens	Evatanepag	-	Gs/β1/γ2	2.9	2021-05-05	doi.org/10.1126/sciadv.abf1268
	7CX4 (No Gprot)	A	Lipid	Prostanoid	EP₂	Homo sapiens	Evatanepag	-		2.9	2021-05-05	doi.org/10.1126/sciadv.abf1268

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