Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:N5 5.7075450
2L:L:Y9 9.605410
3R:R:F36 6.33417
4R:R:L50 3.9975406
5R:R:L62 3.31405
6R:R:L67 4.32529
7R:R:D71 6.208509
8R:R:F81 6.2175406
9R:R:W91 5.51548
10R:R:F106 10.405414
11R:R:L107 3.635404
12R:R:R123 3.8625429
13R:R:Y129 4.085406
14R:R:R137 4.83333676
15R:R:F156 4.69584
16R:R:Y160 12.17414
17R:R:Y163 7.42333614
18R:R:Y164 16.505415
19R:R:Q166 6.28445
20R:R:P177 5.4375414
21R:R:M187 4.405415
22R:R:Y207 5.195629
23R:R:L211 4.3325404
24R:R:F245 4.932529
25R:R:W249 6.526539
26R:R:H252 6.1125437
27R:R:H253 8.1175438
28R:R:W260 6.46504
29R:R:F264 5.915465
30R:R:R274 7.7275433
31R:R:L279 2.0975405
32R:R:Y282 4.98857717
33R:R:N284 4.9925409
34R:R:N288 5.2375429
35R:R:Y292 4.87833629
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:L10 R:R:R274 11.34659.72NoYes003
2R:R:I35 R:R:L279 12.21571.43NoYes075
3R:R:I35 R:R:Y282 13.53253.63NoYes077
4R:R:Q82 R:R:Y282 98.07944.51NoYes167
5L:L:Y9 R:R:Q82 1003.38YesNo106
6L:L:Y9 R:R:I85 15.562414.51YesNo005
7L:L:N5 R:R:I85 14.3089.91YesNo005
8L:L:Y9 R:R:Y164 94.321612.91YesYes105
9R:R:V79 R:R:Y282 25.92526.31NoYes177
10R:R:F36 R:R:V79 24.0156.55YesNo177
11R:R:F36 R:R:I75 25.17573.77YesNo077
12R:R:I75 R:R:S285 26.34154.64NoNo079
13R:R:D71 R:R:S285 26.77355.89YesNo099
14R:R:D71 R:R:N43 49.44054.04YesNo099
15R:R:N43 R:R:P289 24.915411.4NoNo099
16R:R:S281 R:R:Y282 78.99865.09NoYes077
17R:R:S281 R:R:W249 78.86859.88NoYes079
18R:R:N284 R:R:W249 72.80493.39YesYes099
19R:R:N284 R:R:N288 39.14025.45YesYes099
20R:R:D71 R:R:N288 36.76686.73YesYes099
21R:R:P289 R:R:V46 15.10961.77NoNo099
22R:R:A293 R:R:V46 12.64255.09NoNo079
23R:R:L72 R:R:N43 22.43792.75NoNo089
24R:R:L47 R:R:L72 17.51421.38NoNo078
25R:R:L47 R:R:L65 12.59041.38NoNo076
26R:R:L50 R:R:L65 10.12344.15YesNo066
27R:R:Y163 R:R:Y164 85.61919.93YesYes145
28R:R:M187 R:R:Y163 45.6674.79YesYes154
29R:R:M187 R:R:P159 46.41133.35YesNo057
30R:R:G158 R:R:P159 45.33914.06NoNo047
31R:R:F103 R:R:G158 44.25653.01NoNo064
32R:R:F103 R:R:S157 38.68736.61NoNo067
33R:R:L107 R:R:S157 37.54236.01YesNo047
34R:R:L107 R:R:S153 32.8583YesNo048
35R:R:A111 R:R:S153 31.66093.42NoNo068
36R:R:A111 R:R:W150 30.45337.78NoNo069
37R:R:N66 R:R:W150 28.00717.91NoNo099
38R:R:I146 R:R:N66 24.25967.08NoNo079
39R:R:I146 R:R:L62 22.98962.85NoYes075
40R:R:A142 R:R:L62 19.11733.15NoYes075
41R:R:A142 R:R:T59 17.80575.03NoNo076
42R:R:R137 R:R:T59 11.09143.88YesNo066
43R:R:D71 R:R:L67 17.47254.07YesYes099
44R:R:N288 R:R:Y292 22.81794.65YesYes299
45R:R:L67 R:R:Y292 15.97885.86YesYes299
46R:R:Y160 R:R:Y163 32.873611.91YesYes144
47R:R:F106 R:R:Y160 37.365325.79YesYes144
48R:R:F106 R:R:I105 26.77876.28YesNo045
49R:R:F81 R:R:I105 25.51923.77YesNo065
50R:R:F81 R:R:W91 19.22148.02YesYes068
51R:R:H278 R:R:R274 13.407610.16NoYes353
52R:R:F106 R:R:H110 11.27885.66YesNo046
53R:R:F245 R:R:N284 37.08954.83YesYes099
54R:R:F245 R:R:L203 31.74933.65YesNo298
55R:R:R123 R:R:Y292 14.02185.14YesYes299
56R:R:L203 R:R:Y207 25.51924.69NoYes289
57R:R:I238 R:R:Y207 43.75687.25NoYes079
58R:R:I238 R:R:L211 39.14025.71NoYes074
59R:R:L211 R:R:T210 19.46082.95YesNo048
60R:R:T210 R:R:Y124 17.74324.99NoNo088
61R:R:R128 R:R:Y124 14.27686.17NoNo078
62R:R:R184 R:R:W260 11.736810NoYes044
63R:R:H253 R:R:W249 12.076.35YesYes389
64R:R:V241 R:R:Y292 17.83695.05NoYes089
65R:R:L211 R:R:T235 17.63395.9YesNo046
66R:R:T235 R:R:W215 15.895512.13NoNo064
67R:R:H252 R:R:H278 18.27934.78YesNo375
68R:R:H252 R:R:W249 19.67429.52YesYes379
69R:R:R123 R:R:Y207 12.27815.14YesYes299
70R:R:V241 R:R:Y207 12.72063.79NoYes089
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:G1 R:R:Y271 7.24 0 No No 0 3 0 1
L:L:W2 R:R:L266 13.67 0 No No 0 1 0 1
L:L:W2 R:R:Y271 22.19 0 No No 0 3 0 1
L:L:N5 R:R:I85 9.91 5 Yes No 0 5 0 1
L:L:N5 R:R:G90 3.39 5 Yes No 0 5 0 1
L:L:N5 R:R:V174 4.43 5 Yes No 0 4 0 1
L:L:N5 R:R:H176 5.1 5 Yes No 0 4 0 1
L:L:S6 R:R:Y86 7.63 0 No No 0 5 0 1
L:L:G8 R:R:H176 7.94 0 No No 0 4 0 1
L:L:Y9 R:R:Q82 3.38 1 Yes No 0 6 0 1
L:L:Y9 R:R:I85 14.51 1 Yes No 0 5 0 1
L:L:Y9 R:R:H102 7.62 1 Yes No 0 4 0 1
L:L:Y9 R:R:Y164 12.91 1 Yes Yes 0 5 0 1
L:L:L10 R:R:F264 4.87 0 No Yes 0 5 0 1
L:L:L10 R:R:R274 9.72 0 No Yes 0 3 0 1
L:L:L11 R:R:L266 4.15 0 No No 0 1 0 1
R:R:C78 R:R:Q82 4.58 1 No No 7 6 2 1
R:R:C78 R:R:Y282 4.03 1 No Yes 7 7 2 2
R:R:Q82 R:R:Y282 4.51 1 No Yes 6 7 1 2
R:R:R274 R:R:Y86 6.17 3 Yes No 3 5 1 1
R:R:H278 R:R:Y86 7.62 3 No No 5 5 2 1
R:R:H102 R:R:Y164 34.84 1 No Yes 4 5 1 1
R:R:Y163 R:R:Y164 9.93 1 Yes Yes 4 5 2 1
R:R:P177 R:R:Y163 4.17 1 Yes Yes 4 4 1 2
R:R:R184 R:R:Y163 10.29 1 No Yes 4 4 2 2
R:R:P177 R:R:Y164 8.34 1 Yes Yes 4 5 1 1
R:R:H176 R:R:V174 15.22 5 No No 4 4 1 1
R:R:P177 R:R:R184 7.21 1 Yes No 4 4 1 2
R:R:L255 R:R:R274 4.86 0 No Yes 4 3 2 1
R:R:F264 R:R:V259 3.93 6 Yes No 5 4 1 2
R:R:F264 R:R:P265 5.78 6 Yes No 5 3 1 2
R:R:F264 R:R:T270 9.08 6 Yes No 5 4 1 2
R:R:P265 R:R:T270 8.74 6 No No 3 4 2 2
R:R:I275 R:R:Y271 8.46 0 No No 3 3 2 1
R:R:H278 R:R:R274 10.16 3 No Yes 5 3 2 1
L:L:G12 R:R:P177 2.03 0 No Yes 0 4 0 1
R:R:D89 R:R:G90 1.68 0 No No 4 5 2 1
R:R:L172 R:R:V174 1.49 0 No No 1 4 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7XBD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.35
Number of Linked Nodes 258
Number of Links 278
Number of Hubs 35
Number of Links mediated by Hubs 137
Number of Communities 9
Number of Nodes involved in Communities 56
Number of Links involved in Communities 70
Path Summary
Number Of Nodes in MetaPath 71
Number Of Links MetaPath 70
Number of Shortest Paths 38797
Length Of Smallest Path 3
Average Path Length 14.4094
Length of Longest Path 37
Minimum Path Strength 1.24
Average Path Strength 6.09172
Maximum Path Strength 22.385
Minimum Path Correlation 0.7
Average Path Correlation 0.933455
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.0303
Average % Of Corr. Nodes 53.8225
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 46.1792
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • cell communication   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • neuropeptide signaling pathway   • positive regulation of cytosolic calcium ion concentration   • regulation of biological quality   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • polyol metabolic process   • organophosphate metabolic process   • phosphate-containing compound metabolic process   • metabolic process   • alcohol metabolic process   • small molecule metabolic process   • inositol phosphate metabolic process   • phosphorus metabolic process   • behavior   • multicellular organismal process   • feeding behavior   • galanin-activated signaling pathway   • regulation of localization   • positive regulation of cation transmembrane transport   • localization   • positive regulation of monoatomic ion transport   • positive regulation of monoatomic ion transmembrane transport   • monoatomic cation transport   • regulation of potassium ion transmembrane transporter activity   • regulation of monoatomic ion transport   • inorganic ion transmembrane transport   • regulation of potassium ion transmembrane transport   • positive regulation of cation channel activity   • establishment of localization   • regulation of cation channel activity   • inorganic cation transmembrane transport   • transmembrane transport   • regulation of molecular function   • regulation of transmembrane transport   • potassium ion transport   • regulation of potassium ion transport   • transport   • monoatomic ion transmembrane transport   • positive regulation of biological process   • regulation of transmembrane transporter activity   • potassium ion transmembrane transport   • regulation of monoatomic ion transmembrane transport   • positive regulation of large conductance calcium-activated potassium channel activity   • metal ion transport   • regulation of transporter activity   • monoatomic cation transmembrane transport   • positive regulation of molecular function   • positive regulation of transmembrane transport   • monoatomic ion transport   • regulation of metal ion transport   • positive regulation of cellular process   • regulation of monoatomic ion transmembrane transporter activity   • regulation of transport   • positive regulation of potassium ion transport   • positive regulation of transport   • positive regulation of transporter activity   • positive regulation of potassium ion transmembrane transport   • positive regulation of ion transmembrane transporter activity   • regulation of monoatomic cation transmembrane transport   • positive regulation of potassium ion transmembrane transporter activity   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell surface receptor signaling pathway   • phospholipase C-activating G protein-coupled receptor signaling pathway   • system process   • learning or memory   • nervous system process   • cognition   • muscle contraction   • muscle system process   • phosphatidylinositol metabolic process   • glycerophospholipid metabolic process   • primary metabolic process   • phospholipid metabolic process   • glycerolipid metabolic process   • lipid metabolic process   • positive regulation of DNA-templated transcription   • RNA metabolic process   • positive regulation of macromolecule biosynthetic process   • regulation of primary metabolic process   • nucleobase-containing compound metabolic process   • RNA biosynthetic process   • nucleic acid biosynthetic process   • positive regulation of metabolic process   • DNA-templated transcription   • regulation of RNA metabolic process   • transcription by RNA polymerase II   • positive regulation of biosynthetic process   • positive regulation of macromolecule metabolic process   • regulation of nucleobase-containing compound metabolic process   • regulation of RNA biosynthetic process   • regulation of biosynthetic process   • regulation of transcription by RNA polymerase II   • positive regulation of nucleobase-containing compound metabolic process   • regulation of macromolecule metabolic process   • positive regulation of transcription by RNA polymerase II   • nucleobase-containing compound biosynthetic process   • gene expression   • macromolecule biosynthetic process   • nucleic acid metabolic process   • positive regulation of RNA metabolic process   • regulation of gene expression   • biosynthetic process   • positive regulation of RNA biosynthetic process   • regulation of macromolecule biosynthetic process   • macromolecule metabolic process   • regulation of DNA-templated transcription   • regulation of metabolic process   • developmental process   • plasma membrane bounded cell projection organization   • cellular developmental process   • cell projection organization   • cell development   • neuron projection development   • nervous system development   • cellular component organization   • generation of neurons   • neurogenesis   • multicellular organism development   • neuron differentiation   • cell differentiation   • neuron development   • anatomical structure development   • cellular component organization or biogenesis   • system development   • membrane-bounded organelle   • cell projection   • cellular anatomical structure   • organelle   • cilium   • plasma membrane bounded cell projection   • membrane   • cell periphery   • plasma membrane   • protein binding   • binding   • G-protein beta-subunit binding   • fibroblast proliferation   • cell population proliferation   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to oxygen-containing compound   • response to nitrogen compound   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to monoamine stimulus   • response to chemical   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • synapse   • cell junction   • molecular transducer activity   • molecular function activator activity   • signaling receptor binding   • signaling receptor activity   • neuropeptide activity   • signaling receptor activator activity   • hormone activity   • molecular function regulator activity   • neuropeptide hormone activity   • signaling receptor regulator activity   • receptor ligand activity   • galanin receptor activity   • peptide receptor activity   • G protein-coupled receptor activity   • G protein-coupled peptide receptor activity   • transmembrane signaling receptor activity   • neuropeptide receptor activity   • galanin receptor binding   • G protein-coupled receptor binding   • neuropeptide receptor binding   • type 2 galanin receptor binding   • type 1 galanin receptor binding   • type 3 galanin receptor binding   • positive regulation of cell communication   • positive regulation of steroid hormone secretion   • regulation of system process   • regulation of glucocorticoid secretion   • positive regulation of cortisol secretion   • positive regulation of glucocorticoid secretion   • regulation of steroid hormone secretion   • cortisol secretion   • positive regulation of corticosteroid hormone secretion   • regulation of hormone levels   • lipid transport   • regulation of corticosteroid hormone secretion   • regulation of secretion   • endocrine hormone secretion   • positive regulation of lipid transport   • lipid export from cell   • regulation of cortisol secretion   • positive regulation of multicellular organismal process   • glucocorticoid secretion   • regulation of endocrine process   • corticosteroid hormone secretion   • regulation of hormone secretion   • steroid hormone secretion   • regulation of lipid transport   • organic hydroxy compound transport   • positive regulation of secretion by cell   • hormone secretion   • secretion by cell   • regulation of secretion by cell   • positive regulation of hormone secretion   • positive regulation of secretion   • signal release   • regulation of multicellular organismal process   • regulation of signaling   • secretion   • lipid localization   • export from cell   • cell-cell signaling   • positive regulation of lipid localization   • endocrine process   • regulation of lipid localization   • macromolecule localization   • hormone transport   • regulation of cell communication   • positive regulation of signaling   • response to xenobiotic stimulus   • response to estrogen   • positive regulation of programmed cell death   • regulation of apoptotic process   • regulation of programmed cell death   • cell death   • positive regulation of apoptotic process   • apoptotic process   • programmed cell death   • intracellular signal transduction   • protein kinase A signaling   • regulation of developmental process   • epidermis development   • molting cycle process   • regulation of hair cycle   • catagen   • hair cycle phase   • positive regulation of hair follicle maturation   • positive regulation of developmental process   • regulation of timing of catagen   • skin epidermis development   • hair follicle development   • positive regulation of timing of catagen   • hair follicle maturation   • regulation of hair follicle maturation   • epithelium development   • regulation of multicellular organismal development   • biological phase   • hair cycle   • animal organ development   • developmental maturation   • tissue development   • positive regulation of hair follicle development   • skin development   • anatomical structure maturation   • molting cycle   • regulation of hair follicle development   • hair cycle process   • negative regulation of lymphocyte proliferation   • regulation of leukocyte activation   • negative regulation of biological process   • regulation of cell activation   • lymphocyte activation   • negative regulation of lymphocyte activation   • leukocyte proliferation   • leukocyte activation   • negative regulation of mononuclear cell proliferation   • negative regulation of leukocyte proliferation   • lymphocyte proliferation   • negative regulation of cellular process   • regulation of immune system process   • regulation of lymphocyte proliferation   • regulation of leukocyte proliferation   • negative regulation of cell population proliferation   • cell activation   • negative regulation of cell activation   • negative regulation of immune system process   • regulation of cell population proliferation   • mononuclear cell proliferation   • immune system process   • regulation of mononuclear cell proliferation   • negative regulation of multicellular organismal process   • negative regulation of leukocyte activation   • regulation of lymphocyte activation   • regulation of hormone metabolic process   • steroid metabolic process   • regulation of steroid metabolic process   • regulation of lipid metabolic process   • hormone metabolic process   • glucocorticoid metabolic process   • regulation of glucocorticoid metabolic process   • response to immobilization stress   • response to stress   • response to peptide hormone   • response to insulin   • protein localization   • establishment of protein localization   • cellular localization   • nitrogen compound transport   • protein localization to extracellular region   • peptide secretion   • amide transport   • cellular macromolecule localization   • establishment of protein localization to extracellular region   • protein secretion   • peptide transport   • protein transport   • peptide hormone secretion   • insulin secretion   • intracellular anatomical structure   • intracellular vesicle   • intracellular membrane-bounded organelle   • endomembrane system   • intracellular organelle   • cytoplasmic vesicle   • secretory granule   • secretory vesicle   • cytoplasm   • somatodendritic compartment   • cell body   • neuronal cell body   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • sensory perception of chemical stimulus   • sensory perception   • sensory perception of taste   • sensory organ development   • eye development   • retina development in camera-type eye   • visual system development   • camera-type eye development   • sensory system development   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signaling cassette   • synaptic signaling   • cellular response to acetylcholine   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • organelle membrane   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtO43603
Sequence
>7XBD_nogp_Chain_R
EAVIVPLLF ALIFLVGTV GNTLVLAVL LRGGQAVST TNLFILNLG 
VADLCFILC CVPFQATIY TLDGWVFGS LLCKAVHFL IFLTMHASS 
FTLAAVSLD RYLAIRYPL HSRELRTPR NALAAIGLI WGLSLLFSG 
PYLSYYRQS QLANLTVCH PAWSAPRRR AMDICTFVF SYLLPVLVL 
GLTYARTLR YLWRAVDPV AAGSGARRA KRKVTRMIL IVAALFCLC 
WMPHHALIL CVWFGQFPL TRATYALRI LSHLVSYAN SCVNPIVYA 
LVSKHFR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7XBDAPeptideGalaninGAL2Homo sapiensGalanin-chim(NtGi2L-Gs-CtGq)/β1/γ23.112022-07-1310.1371/journal.pbio.3001714
7XBD (No Gprot) APeptideGalaninGAL2Homo sapiensGalanin-3.112022-07-1310.1371/journal.pbio.3001714
7XJLAPeptideGalaninGAL2Homo sapiensSpexin-chim(NtGi2L-Gs-CtGq)/β1/γ23.52022-06-2910.1073/pnas.2121465119
7XJL (No Gprot) APeptideGalaninGAL2Homo sapiensSpexin-3.52022-06-2910.1073/pnas.2121465119
7XJKAPeptideGalaninGAL2Homo sapiensGalanin-chim(NtGi2L-Gs-CtGq)/β1/γ23.32022-06-2910.1073/pnas.2121465119
7XJK (No Gprot) APeptideGalaninGAL2Homo sapiensGalanin-3.32022-06-2910.1073/pnas.2121465119
7WQ4APeptideGalaninGAL2Homo sapiensGalanin-chim(NtGi1-Gs-CtGq)/β1/γ22.62022-04-2010.1038/s41467-022-29072-3
7WQ4 (No Gprot) APeptideGalaninGAL2Homo sapiensGalanin-2.62022-04-2010.1038/s41467-022-29072-3




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Download 7XBD_nogp.zip



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