psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:G1	R:R:Y271	7.24	No	No	0	0	3
2	L:L:W2	R:R:L266	13.67	No	No	0	0	1
3	L:L:W2	R:R:Y271	22.19	No	No	0	0	3
4	L:L:S6	L:L:T3	6.4	No	No	0	0	0
5	L:L:N5	R:R:I85	9.91	Yes	No	0	0	5
6	L:L:N5	R:R:G90	3.39	Yes	No	0	0	5
7	L:L:N5	R:R:V174	4.43	Yes	No	5	0	4
8	L:L:N5	R:R:H176	5.1	Yes	No	5	0	4
9	L:L:S6	R:R:Y86	7.63	No	No	0	0	5
10	L:L:A7	L:L:V16	3.39	No	No	0	0	0
11	L:L:G8	L:L:V16	3.68	No	No	0	0	0
12	L:L:G8	R:R:H176	7.94	No	No	0	0	4
13	L:L:Y9	R:R:Q82	3.38	Yes	No	1	0	6
14	L:L:Y9	R:R:I85	14.51	Yes	No	0	0	5
15	L:L:Y9	R:R:H102	7.62	Yes	No	1	0	4
16	L:L:Y9	R:R:Y164	12.91	Yes	Yes	1	0	5
17	L:L:L10	L:L:L11	4.15	No	No	0	0	0
18	L:L:L10	R:R:F264	4.87	No	Yes	0	0	5
19	L:L:L10	R:R:R274	9.72	No	Yes	0	0	3
20	L:L:L11	R:R:L266	4.15	No	No	0	0	1
21	L:L:G12	L:L:P13	4.06	No	No	0	0	0
22	L:L:A15	L:L:H14	4.39	No	No	0	0	0
23	R:R:P29	R:R:V28	5.3	No	No	0	5	6
24	R:R:L279	R:R:L31	4.15	Yes	No	0	5	4
25	R:R:A83	R:R:F32	8.32	No	No	0	6	7
26	R:R:F32	R:R:Y282	7.22	No	Yes	0	7	7
27	R:R:I35	R:R:Y282	3.63	No	Yes	0	7	7
28	R:R:F36	R:R:T40	7.78	Yes	No	0	7	6
29	R:R:F36	R:R:I75	3.77	Yes	No	0	7	7
30	R:R:F36	R:R:V79	6.55	Yes	No	1	7	7
31	R:R:F36	R:R:P80	7.22	Yes	No	1	7	8
32	R:R:G39	R:R:I75	5.29	No	No	0	8	7
33	R:R:C286	R:R:G39	3.92	No	No	0	7	8
34	R:R:G42	R:R:V41	3.68	No	No	0	7	4
35	R:R:G42	R:R:P289	4.06	No	No	0	7	9
36	R:R:D71	R:R:N43	4.04	Yes	No	0	9	9
37	R:R:N43	R:R:P289	11.4	No	No	0	9	9
38	R:R:A293	R:R:V46	5.09	No	No	0	7	9
39	R:R:R52	R:R:V49	3.92	No	No	0	4	7
40	R:R:F299	R:R:V49	3.93	No	No	0	8	7
41	R:R:L50	R:R:N61	4.12	Yes	No	0	6	7
42	R:R:L50	R:R:L65	4.15	Yes	No	0	6	6
43	R:R:F299	R:R:L50	4.87	No	Yes	0	8	6
44	R:R:G54	R:R:Q55	4.93	No	No	0	6	6
45	R:R:L62	R:R:V57	4.47	Yes	No	0	5	6
46	R:R:N61	R:R:S58	4.47	No	No	0	7	8
47	R:R:R137	R:R:T59	3.88	Yes	No	0	6	6
48	R:R:A142	R:R:T59	5.03	No	No	0	7	6
49	R:R:R137	R:R:T60	3.88	Yes	No	0	6	7
50	R:R:D122	R:R:F63	8.36	No	No	0	8	7
51	R:R:I146	R:R:N66	7.08	No	No	0	7	9
52	R:R:N66	R:R:W150	7.91	No	No	0	9	9
53	R:R:D71	R:R:L67	4.07	Yes	Yes	0	9	9
54	R:R:L67	R:R:T115	4.42	Yes	No	0	9	8
55	R:R:L116	R:R:L67	5.54	No	Yes	2	8	9
56	R:R:L67	R:R:Y292	5.86	Yes	Yes	2	9	9
57	R:R:D71	R:R:S112	10.31	Yes	No	0	9	9
58	R:R:D71	R:R:S285	5.89	Yes	No	0	9	9
59	R:R:D71	R:R:N288	6.73	Yes	Yes	0	9	9
60	R:R:C78	R:R:F74	9.78	No	No	1	7	7
61	R:R:F74	R:R:T108	5.19	No	No	0	7	8
62	R:R:F74	R:R:Y282	4.13	No	Yes	1	7	7
63	R:R:I75	R:R:S285	4.64	No	No	0	7	9
64	R:R:C78	R:R:Q82	4.58	No	No	1	7	6
65	R:R:C78	R:R:Y282	4.03	No	Yes	1	7	7
66	R:R:P80	R:R:V79	3.53	No	No	1	8	7
67	R:R:V79	R:R:Y282	6.31	No	Yes	1	7	7
68	R:R:F81	R:R:W91	8.02	Yes	Yes	0	6	8
69	R:R:F81	R:R:V101	10.49	Yes	No	0	6	5
70	R:R:F81	R:R:I105	3.77	Yes	No	0	6	5
71	R:R:Q82	R:R:Y282	4.51	No	Yes	1	6	7
72	R:R:R274	R:R:Y86	6.17	Yes	No	3	3	5
73	R:R:H278	R:R:Y86	7.62	No	No	3	5	5
74	R:R:C98	R:R:W91	10.45	No	Yes	4	9	8
75	R:R:C175	R:R:W91	6.53	No	Yes	4	9	8
76	R:R:Q166	R:R:S95	8.66	Yes	No	0	5	3
77	R:R:C98	R:R:Q166	7.63	No	Yes	4	9	5
78	R:R:C175	R:R:C98	7.28	No	No	4	9	9
79	R:R:K99	R:R:R165	3.71	No	No	0	6	4
80	R:R:H102	R:R:Y164	34.84	No	Yes	1	4	5
81	R:R:F103	R:R:S157	6.61	No	No	0	6	7
82	R:R:F103	R:R:L161	4.87	No	No	0	6	5
83	R:R:F106	R:R:I105	6.28	Yes	No	0	4	5
84	R:R:F106	R:R:H110	5.66	Yes	No	0	4	6
85	R:R:F106	R:R:Y160	25.79	Yes	Yes	1	4	4
86	R:R:F106	R:R:T191	3.89	Yes	No	1	4	5
87	R:R:L107	R:R:L154	4.15	Yes	No	0	4	4
88	R:R:L107	R:R:S157	6.01	Yes	No	0	4	7
89	R:R:M109	R:R:W249	3.49	No	Yes	0	7	9
90	R:R:F156	R:R:H110	6.79	Yes	No	0	4	6
91	R:R:A111	R:R:W150	7.78	No	No	0	6	9
92	R:R:A111	R:R:S153	3.42	No	No	0	6	8
93	R:R:P199	R:R:S113	5.34	No	No	2	8	7
94	R:R:F245	R:R:S113	6.61	Yes	No	2	9	7
95	R:R:F114	R:R:F156	4.29	No	Yes	8	6	4
96	R:R:L116	R:R:N288	4.12	No	Yes	2	8	9
97	R:R:L116	R:R:Y292	3.52	No	Yes	2	8	9
98	R:R:A117	R:R:V202	3.39	No	No	0	7	6
99	R:R:R123	R:R:V119	3.92	Yes	No	2	9	9
100	R:R:V119	R:R:Y292	5.05	No	Yes	2	9	9
101	R:R:L203	R:R:S120	4.5	No	No	2	8	9
102	R:R:S120	R:R:T206	6.4	No	No	0	9	7
103	R:R:S120	R:R:Y207	7.63	No	Yes	2	9	9
104	R:R:D122	R:R:R137	11.91	No	Yes	0	8	6
105	R:R:R123	R:R:Y207	5.14	Yes	Yes	2	9	9
106	R:R:R123	R:R:Y292	5.14	Yes	Yes	2	9	9
107	R:R:R128	R:R:Y124	6.17	No	No	0	7	8
108	R:R:R209	R:R:Y124	7.2	No	No	0	4	8
109	R:R:T210	R:R:Y124	4.99	No	No	0	8	8
110	R:R:A126	R:R:R137	6.91	No	Yes	0	8	6
111	R:R:R128	R:R:Y129	11.32	No	Yes	0	7	6
112	R:R:R128	R:R:Y213	23.66	No	No	0	7	5
113	R:R:P139	R:R:T138	3.5	No	No	0	2	7
114	R:R:R140	R:R:T138	3.88	No	No	0	4	7
115	R:R:F156	R:R:L155	3.65	Yes	No	0	4	4
116	R:R:F156	R:R:F194	7.5	Yes	No	0	4	4
117	R:R:G158	R:R:P159	4.06	No	No	0	4	7
118	R:R:M187	R:R:P159	3.35	Yes	No	0	5	7
119	R:R:Y160	R:R:Y163	11.91	Yes	Yes	1	4	4
120	R:R:M187	R:R:Y160	5.99	Yes	Yes	1	5	4
121	R:R:T191	R:R:Y160	4.99	No	Yes	1	5	4
122	R:R:S162	R:R:W179	6.18	No	No	0	4	4
123	R:R:Y163	R:R:Y164	9.93	Yes	Yes	1	4	5
124	R:R:P177	R:R:Y163	4.17	Yes	Yes	1	4	4
125	R:R:R184	R:R:Y163	10.29	No	Yes	1	4	4
126	R:R:M187	R:R:Y163	4.79	Yes	Yes	1	5	4
127	R:R:D188	R:R:Y163	3.45	No	Yes	0	5	4
128	R:R:P177	R:R:Y164	8.34	Yes	Yes	1	4	5
129	R:R:A178	R:R:R165	8.3	No	No	0	4	4
130	R:R:Q166	R:R:T173	4.25	Yes	No	0	5	5
131	R:R:C175	R:R:Q166	4.58	No	Yes	4	9	5
132	R:R:H176	R:R:V174	15.22	No	No	5	4	4
133	R:R:P177	R:R:R184	7.21	Yes	No	1	4	4
134	R:R:R183	R:R:W179	4	No	No	0	2	4
135	R:R:M187	R:R:W179	3.49	Yes	No	0	5	4
136	R:R:P182	R:R:S180	7.13	No	No	0	1	4
137	R:R:R183	R:R:S180	3.95	No	No	0	2	4
138	R:R:R184	R:R:W260	10	No	Yes	0	4	4
139	R:R:R185	R:R:W260	10	No	Yes	0	3	4
140	R:R:D188	R:R:I256	4.2	No	No	0	5	6
141	R:R:D188	R:R:W260	6.7	No	Yes	0	5	4
142	R:R:F192	R:R:Y196	5.16	No	No	3	5	8
143	R:R:F192	R:R:L197	6.09	No	No	0	5	4
144	R:R:F192	R:R:H253	14.71	No	Yes	3	5	8
145	R:R:F194	R:R:V193	3.93	No	No	0	4	4
146	R:R:M250	R:R:Y196	9.58	No	No	0	5	8
147	R:R:H253	R:R:Y196	5.44	Yes	No	3	8	8
148	R:R:F245	R:R:P199	4.33	Yes	No	2	9	8
149	R:R:F245	R:R:V200	5.24	Yes	No	0	9	6
150	R:R:L203	R:R:Y207	4.69	No	Yes	2	8	9
151	R:R:F245	R:R:L203	3.65	Yes	No	2	9	8
152	R:R:I238	R:R:Y207	7.25	No	Yes	0	7	9
153	R:R:V241	R:R:Y207	3.79	No	Yes	0	8	9
154	R:R:L211	R:R:T235	5.9	Yes	No	0	4	6
155	R:R:I238	R:R:L211	5.71	No	Yes	0	7	4
156	R:R:R216	R:R:Y213	20.58	No	No	0	5	5
157	R:R:K231	R:R:W215	3.48	No	No	0	7	4
158	R:R:T235	R:R:W215	12.13	No	No	0	6	4
159	R:R:R216	R:R:V218	10.46	No	No	0	5	5
160	R:R:D219	R:R:P220	6.44	No	No	0	4	4
161	R:R:A227	R:R:P220	3.74	No	No	0	4	4
162	R:R:A223	R:R:R228	4.15	No	No	0	2	3
163	R:R:M237	R:R:V295	4.56	No	No	0	8	6
164	R:R:V241	R:R:Y292	5.05	No	Yes	0	8	9
165	R:R:F245	R:R:N284	4.83	Yes	Yes	0	9	9
166	R:R:C248	R:R:N284	6.3	No	Yes	0	8	9
167	R:R:H252	R:R:W249	9.52	Yes	Yes	3	7	9
168	R:R:H253	R:R:W249	6.35	Yes	Yes	3	8	9
169	R:R:S281	R:R:W249	9.88	No	Yes	0	7	9
170	R:R:N284	R:R:W249	3.39	Yes	Yes	0	9	9
171	R:R:M250	R:R:P251	3.35	No	No	0	5	9
172	R:R:P251	R:R:V280	5.3	No	No	0	9	8
173	R:R:H252	R:R:H253	5.97	Yes	Yes	3	7	8
174	R:R:H252	R:R:S277	4.18	Yes	No	0	7	6
175	R:R:H252	R:R:H278	4.78	Yes	No	3	7	5
176	R:R:L255	R:R:R274	4.86	No	Yes	0	4	3
177	R:R:F264	R:R:V259	3.93	Yes	No	0	5	4
178	R:R:F264	R:R:P265	5.78	Yes	No	6	5	3
179	R:R:F264	R:R:T270	9.08	Yes	No	6	5	4
180	R:R:P265	R:R:T267	6.99	No	No	0	3	3
181	R:R:P265	R:R:T270	8.74	No	No	6	3	4
182	R:R:I275	R:R:Y271	8.46	No	No	0	3	3
183	R:R:H278	R:R:R274	10.16	No	Yes	3	5	3
184	R:R:S281	R:R:Y282	5.09	No	Yes	0	7	7
185	R:R:N284	R:R:N288	5.45	Yes	Yes	0	9	9
186	R:R:N288	R:R:Y292	4.65	Yes	Yes	2	9	9
187	R:R:K297	R:R:R300	9.9	No	No	0	4	8
188	R:R:L198	R:R:P199	3.28	No	No	0	5	8
189	R:R:R229	R:R:R236	3.2	No	No	9	4	6
190	R:R:A142	R:R:L62	3.15	No	Yes	0	7	5
191	R:R:M109	R:R:S195	3.07	No	No	0	7	6
192	R:R:I238	R:R:V234	3.07	No	No	0	7	7
193	R:R:I240	R:R:V291	3.07	No	No	0	6	8
194	R:R:F103	R:R:G158	3.01	No	No	0	6	4
195	R:R:F261	R:R:W260	3.01	No	Yes	0	4	4
196	R:R:L107	R:R:S153	3	Yes	No	0	4	8
197	R:R:L169	R:R:S167	3	No	No	0	2	1
198	R:R:R232	R:R:W215	3	No	No	0	4	4
199	R:R:L121	R:R:V202	2.98	No	No	0	6	6
200	R:R:L214	R:R:V234	2.98	No	No	0	7	7
201	R:R:L244	R:R:V287	2.98	No	No	0	7	6
202	R:R:L76	R:R:T40	2.95	No	No	0	4	6
203	R:R:L88	R:R:T84	2.95	No	No	0	4	3
204	R:R:L88	R:R:T87	2.95	No	No	0	4	4
205	R:R:L121	R:R:T206	2.95	No	No	0	6	7
206	R:R:L211	R:R:T210	2.95	Yes	No	0	4	8
207	R:R:I27	R:R:L31	2.85	No	No	0	5	4
208	R:R:I64	R:R:L50	2.85	No	Yes	0	8	6
209	R:R:I146	R:R:L62	2.85	No	Yes	0	7	5
210	R:R:I149	R:R:N66	2.83	No	No	0	7	9
211	R:R:Q168	R:R:T173	2.83	No	No	0	3	5
212	R:R:K99	R:R:L161	2.82	No	No	0	6	5
213	R:R:L143	R:R:L62	2.77	No	Yes	0	3	5
214	R:R:A145	R:R:F63	2.77	No	No	0	5	7
215	R:R:L211	R:R:L239	2.77	Yes	No	0	4	5
216	R:R:A293	R:R:F299	2.77	No	No	0	7	8
217	R:R:L72	R:R:N43	2.75	No	No	0	8	9
218	R:R:A242	R:R:Y207	2.67	No	Yes	0	8	9
219	R:R:F32	R:R:V28	2.62	No	No	0	7	6
220	R:R:A70	R:R:W150	2.59	No	No	0	8	9
221	R:R:F81	R:R:T84	2.59	Yes	No	0	6	3
222	R:R:A181	R:R:W260	2.59	No	Yes	0	3	4
223	R:R:S133	R:R:Y129	2.54	No	Yes	0	6	6
224	R:R:F261	R:R:I189	2.51	No	No	0	4	5
225	R:R:L131	R:R:R134	2.43	No	No	0	6	4
226	R:R:G53	R:R:G54	2.11	No	No	0	5	6
227	L:L:G12	R:R:P177	2.03	No	Yes	0	0	4
228	R:R:G39	R:R:V38	1.84	No	No	0	8	6
229	R:R:A283	R:R:C248	1.81	No	No	0	5	8
230	R:R:P289	R:R:V46	1.77	No	No	0	9	9
231	R:R:P139	R:R:T59	1.75	No	No	0	2	6
232	R:R:G68	R:R:L67	1.71	No	Yes	0	8	9
233	R:R:C246	R:R:V200	1.71	No	No	0	5	6
234	R:R:C73	R:R:T108	1.69	No	No	0	7	8
235	R:R:D89	R:R:G90	1.68	No	No	0	4	5
236	R:R:A269	R:R:T267	1.68	No	No	0	2	3
237	R:R:G262	R:R:Q263	1.64	No	No	0	3	4
238	R:R:A118	R:R:I149	1.62	No	No	0	7	7
239	R:R:A227	R:R:K231	1.61	No	No	0	4	7
240	R:R:A254	R:R:M250	1.61	No	No	0	6	5
241	R:R:V241	R:R:V291	1.6	No	No	0	8	8
242	R:R:V287	R:R:V291	1.6	No	No	0	6	8
243	R:R:C77	R:R:L104	1.59	No	No	0	4	5
244	R:R:A100	R:R:L97	1.58	No	No	0	4	5
245	R:R:A293	R:R:L294	1.58	No	No	0	7	6
246	R:R:G224	R:R:R228	1.5	No	No	0	3	3
247	L:L:L4	L:L:V16	1.49	No	No	0	0	0
248	R:R:L30	R:R:V26	1.49	No	No	0	5	6
249	R:R:L45	R:R:V41	1.49	No	No	0	6	4
250	R:R:L47	R:R:V69	1.49	No	No	0	7	6
251	R:R:L172	R:R:V174	1.49	No	No	0	1	4
252	R:R:L72	R:R:T44	1.47	No	No	0	8	4
253	R:R:N141	R:R:T138	1.46	No	No	0	4	7
254	R:R:K233	R:R:M237	1.44	No	No	0	7	8
255	R:R:I35	R:R:L279	1.43	No	Yes	0	7	5
256	R:R:I275	R:R:L279	1.43	No	Yes	0	3	5
257	R:R:G94	R:R:W91	1.41	No	Yes	0	7	8
258	R:R:P130	R:R:Y129	1.39	No	Yes	0	8	6
259	R:R:H298	R:R:S296	1.39	No	No	0	5	8
260	R:R:L47	R:R:L65	1.38	No	No	0	7	6
261	R:R:L47	R:R:L72	1.38	No	No	0	7	8
262	R:R:L104	R:R:L107	1.38	No	Yes	0	5	4
263	R:R:L125	R:R:L136	1.38	No	No	7	5	3
264	R:R:L148	R:R:L152	1.38	No	No	0	3	4
265	R:R:L197	R:R:L201	1.38	No	No	0	4	3
266	R:R:L201	R:R:L205	1.38	No	No	0	3	4
267	R:R:L276	R:R:L279	1.38	No	Yes	0	6	5
268	R:R:R229	R:R:S225	1.32	No	No	0	4	3
269	R:R:I127	R:R:R123	1.25	No	Yes	0	8	9
270	R:R:K233	R:R:R229	1.24	No	No	9	7	4
271	R:R:K233	R:R:R236	1.24	No	No	9	7	6
272	R:R:F114	R:R:L152	1.22	No	No	8	6	4
273	R:R:F156	R:R:L152	1.22	Yes	No	8	4	4
274	R:R:L125	R:R:R137	1.21	No	Yes	7	5	6
275	R:R:L136	R:R:R137	1.21	No	Yes	7	3	6
276	R:R:L97	R:R:W91	1.14	No	Yes	0	5	8
277	R:R:H132	R:R:Y129	1.09	No	Yes	0	5	6
278	R:R:R228	R:R:R232	1.07	No	No	0	3	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:N5	5.7075	4	5	0
2	L:L:Y9	9.605	4	1	0
3	R:R:F36	6.33	4	1	7
4	R:R:L50	3.9975	4	0	6
5	R:R:L62	3.31	4	0	5
6	R:R:L67	4.32	5	2	9
7	R:R:D71	6.208	5	0	9
8	R:R:F81	6.2175	4	0	6
9	R:R:W91	5.51	5	4	8
10	R:R:F106	10.405	4	1	4
11	R:R:L107	3.635	4	0	4
12	R:R:R123	3.8625	4	2	9
13	R:R:Y129	4.085	4	0	6
14	R:R:R137	4.83333	6	7	6
15	R:R:F156	4.69	5	8	4
16	R:R:Y160	12.17	4	1	4
17	R:R:Y163	7.42333	6	1	4
18	R:R:Y164	16.505	4	1	5
19	R:R:Q166	6.28	4	4	5
20	R:R:P177	5.4375	4	1	4
21	R:R:M187	4.405	4	1	5
22	R:R:Y207	5.195	6	2	9
23	R:R:L211	4.3325	4	0	4
24	R:R:F245	4.932	5	2	9
25	R:R:W249	6.526	5	3	9
26	R:R:H252	6.1125	4	3	7
27	R:R:H253	8.1175	4	3	8
28	R:R:W260	6.46	5	0	4
29	R:R:F264	5.915	4	6	5
30	R:R:R274	7.7275	4	3	3
31	R:R:L279	2.0975	4	0	5
32	R:R:Y282	4.98857	7	1	7
33	R:R:N284	4.9925	4	0	9
34	R:R:N288	5.2375	4	2	9
35	R:R:Y292	4.87833	6	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:L10	R:R:R274	11.3465	9.72	No	Yes	0	0	3
2	R:R:I35	R:R:L279	12.2157	1.43	No	Yes	0	7	5
3	R:R:I35	R:R:Y282	13.5325	3.63	No	Yes	0	7	7
4	R:R:Q82	R:R:Y282	98.0794	4.51	No	Yes	1	6	7
5	L:L:Y9	R:R:Q82	100	3.38	Yes	No	1	0	6
6	L:L:Y9	R:R:I85	15.5624	14.51	Yes	No	0	0	5
7	L:L:N5	R:R:I85	14.308	9.91	Yes	No	0	0	5
8	L:L:Y9	R:R:Y164	94.3216	12.91	Yes	Yes	1	0	5
9	R:R:V79	R:R:Y282	25.9252	6.31	No	Yes	1	7	7
10	R:R:F36	R:R:V79	24.015	6.55	Yes	No	1	7	7
11	R:R:F36	R:R:I75	25.1757	3.77	Yes	No	0	7	7
12	R:R:I75	R:R:S285	26.3415	4.64	No	No	0	7	9
13	R:R:D71	R:R:S285	26.7735	5.89	Yes	No	0	9	9
14	R:R:D71	R:R:N43	49.4405	4.04	Yes	No	0	9	9
15	R:R:N43	R:R:P289	24.9154	11.4	No	No	0	9	9
16	R:R:S281	R:R:Y282	78.9986	5.09	No	Yes	0	7	7
17	R:R:S281	R:R:W249	78.8685	9.88	No	Yes	0	7	9
18	R:R:N284	R:R:W249	72.8049	3.39	Yes	Yes	0	9	9
19	R:R:N284	R:R:N288	39.1402	5.45	Yes	Yes	0	9	9
20	R:R:D71	R:R:N288	36.7668	6.73	Yes	Yes	0	9	9
21	R:R:P289	R:R:V46	15.1096	1.77	No	No	0	9	9
22	R:R:A293	R:R:V46	12.6425	5.09	No	No	0	7	9
23	R:R:L72	R:R:N43	22.4379	2.75	No	No	0	8	9
24	R:R:L47	R:R:L72	17.5142	1.38	No	No	0	7	8
25	R:R:L47	R:R:L65	12.5904	1.38	No	No	0	7	6
26	R:R:L50	R:R:L65	10.1234	4.15	Yes	No	0	6	6
27	R:R:Y163	R:R:Y164	85.6191	9.93	Yes	Yes	1	4	5
28	R:R:M187	R:R:Y163	45.667	4.79	Yes	Yes	1	5	4
29	R:R:M187	R:R:P159	46.4113	3.35	Yes	No	0	5	7
30	R:R:G158	R:R:P159	45.3391	4.06	No	No	0	4	7
31	R:R:F103	R:R:G158	44.2565	3.01	No	No	0	6	4
32	R:R:F103	R:R:S157	38.6873	6.61	No	No	0	6	7
33	R:R:L107	R:R:S157	37.5423	6.01	Yes	No	0	4	7
34	R:R:L107	R:R:S153	32.858	3	Yes	No	0	4	8
35	R:R:A111	R:R:S153	31.6609	3.42	No	No	0	6	8
36	R:R:A111	R:R:W150	30.4533	7.78	No	No	0	6	9
37	R:R:N66	R:R:W150	28.0071	7.91	No	No	0	9	9
38	R:R:I146	R:R:N66	24.2596	7.08	No	No	0	7	9
39	R:R:I146	R:R:L62	22.9896	2.85	No	Yes	0	7	5
40	R:R:A142	R:R:L62	19.1173	3.15	No	Yes	0	7	5
41	R:R:A142	R:R:T59	17.8057	5.03	No	No	0	7	6
42	R:R:R137	R:R:T59	11.0914	3.88	Yes	No	0	6	6
43	R:R:D71	R:R:L67	17.4725	4.07	Yes	Yes	0	9	9
44	R:R:N288	R:R:Y292	22.8179	4.65	Yes	Yes	2	9	9
45	R:R:L67	R:R:Y292	15.9788	5.86	Yes	Yes	2	9	9
46	R:R:Y160	R:R:Y163	32.8736	11.91	Yes	Yes	1	4	4
47	R:R:F106	R:R:Y160	37.3653	25.79	Yes	Yes	1	4	4
48	R:R:F106	R:R:I105	26.7787	6.28	Yes	No	0	4	5
49	R:R:F81	R:R:I105	25.5192	3.77	Yes	No	0	6	5
50	R:R:F81	R:R:W91	19.2214	8.02	Yes	Yes	0	6	8
51	R:R:H278	R:R:R274	13.4076	10.16	No	Yes	3	5	3
52	R:R:F106	R:R:H110	11.2788	5.66	Yes	No	0	4	6
53	R:R:F245	R:R:N284	37.0895	4.83	Yes	Yes	0	9	9
54	R:R:F245	R:R:L203	31.7493	3.65	Yes	No	2	9	8
55	R:R:R123	R:R:Y292	14.0218	5.14	Yes	Yes	2	9	9
56	R:R:L203	R:R:Y207	25.5192	4.69	No	Yes	2	8	9
57	R:R:I238	R:R:Y207	43.7568	7.25	No	Yes	0	7	9
58	R:R:I238	R:R:L211	39.1402	5.71	No	Yes	0	7	4
59	R:R:L211	R:R:T210	19.4608	2.95	Yes	No	0	4	8
60	R:R:T210	R:R:Y124	17.7432	4.99	No	No	0	8	8
61	R:R:R128	R:R:Y124	14.2768	6.17	No	No	0	7	8
62	R:R:R184	R:R:W260	11.7368	10	No	Yes	0	4	4
63	R:R:H253	R:R:W249	12.07	6.35	Yes	Yes	3	8	9
64	R:R:V241	R:R:Y292	17.8369	5.05	No	Yes	0	8	9
65	R:R:L211	R:R:T235	17.6339	5.9	Yes	No	0	4	6
66	R:R:T235	R:R:W215	15.8955	12.13	No	No	0	6	4
67	R:R:H252	R:R:H278	18.2793	4.78	Yes	No	3	7	5
68	R:R:H252	R:R:W249	19.6742	9.52	Yes	Yes	3	7	9
69	R:R:R123	R:R:Y207	12.2781	5.14	Yes	Yes	2	9	9
70	R:R:V241	R:R:Y207	12.7206	3.79	No	Yes	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:G1	R:R:Y271	7.24	0	No	No	0	3	0	1
L:L:W2	R:R:L266	13.67	0	No	No	0	1	0	1
L:L:W2	R:R:Y271	22.19	0	No	No	0	3	0	1
L:L:N5	R:R:I85	9.91	5	Yes	No	0	5	0	1
L:L:N5	R:R:G90	3.39	5	Yes	No	0	5	0	1
L:L:N5	R:R:V174	4.43	5	Yes	No	0	4	0	1
L:L:N5	R:R:H176	5.1	5	Yes	No	0	4	0	1
L:L:S6	R:R:Y86	7.63	0	No	No	0	5	0	1
L:L:G8	R:R:H176	7.94	0	No	No	0	4	0	1
L:L:Y9	R:R:Q82	3.38	1	Yes	No	0	6	0	1
L:L:Y9	R:R:I85	14.51	1	Yes	No	0	5	0	1
L:L:Y9	R:R:H102	7.62	1	Yes	No	0	4	0	1
L:L:Y9	R:R:Y164	12.91	1	Yes	Yes	0	5	0	1
L:L:L10	R:R:F264	4.87	0	No	Yes	0	5	0	1
L:L:L10	R:R:R274	9.72	0	No	Yes	0	3	0	1
L:L:L11	R:R:L266	4.15	0	No	No	0	1	0	1
R:R:C78	R:R:Q82	4.58	1	No	No	7	6	2	1
R:R:C78	R:R:Y282	4.03	1	No	Yes	7	7	2	2
R:R:Q82	R:R:Y282	4.51	1	No	Yes	6	7	1	2
R:R:R274	R:R:Y86	6.17	3	Yes	No	3	5	1	1
R:R:H278	R:R:Y86	7.62	3	No	No	5	5	2	1
R:R:H102	R:R:Y164	34.84	1	No	Yes	4	5	1	1
R:R:Y163	R:R:Y164	9.93	1	Yes	Yes	4	5	2	1
R:R:P177	R:R:Y163	4.17	1	Yes	Yes	4	4	1	2
R:R:R184	R:R:Y163	10.29	1	No	Yes	4	4	2	2
R:R:P177	R:R:Y164	8.34	1	Yes	Yes	4	5	1	1
R:R:H176	R:R:V174	15.22	5	No	No	4	4	1	1
R:R:P177	R:R:R184	7.21	1	Yes	No	4	4	1	2
R:R:L255	R:R:R274	4.86	0	No	Yes	4	3	2	1
R:R:F264	R:R:V259	3.93	6	Yes	No	5	4	1	2
R:R:F264	R:R:P265	5.78	6	Yes	No	5	3	1	2
R:R:F264	R:R:T270	9.08	6	Yes	No	5	4	1	2
R:R:P265	R:R:T270	8.74	6	No	No	3	4	2	2
R:R:I275	R:R:Y271	8.46	0	No	No	3	3	2	1
R:R:H278	R:R:R274	10.16	3	No	Yes	5	3	2	1
L:L:G12	R:R:P177	2.03	0	No	Yes	0	4	0	1
R:R:D89	R:R:G90	1.68	0	No	No	4	5	2	1
R:R:L172	R:R:V174	1.49	0	No	No	1	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7XBD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.35
Number of Linked Nodes	258
Number of Links	278
Number of Hubs	35
Number of Links mediated by Hubs	137
Number of Communities	9
Number of Nodes involved in Communities	56
Number of Links involved in Communities	70

Path Summary
Number Of Nodes in MetaPath	71
Number Of Links MetaPath	70
Number of Shortest Paths	38797
Length Of Smallest Path	3
Average Path Length	14.4094
Length of Longest Path	37
Minimum Path Strength	1.24
Average Path Strength	6.09172
Maximum Path Strength	22.385
Minimum Path Correlation	0.7
Average Path Correlation	0.933377
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	53.821
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.1792
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • molecular function activator activity • signaling receptor binding • neuropeptide activity • signaling receptor activator activity • hormone activity • protein binding • molecular function regulator activity • neuropeptide hormone activity • signaling receptor regulator activity • receptor ligand activity • galanin receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • neuropeptide receptor activity • galanin receptor binding • G protein-coupled receptor binding • neuropeptide receptor binding • type 2 galanin receptor binding • type 1 galanin receptor binding • type 3 galanin receptor binding • positive regulation of cell communication • multicellular organismal process • regulation of localization • system process • regulation of cellular process • positive regulation of steroid hormone secretion • regulation of system process • cell communication • regulation of glucocorticoid secretion • localization • positive regulation of cortisol secretion • positive regulation of glucocorticoid secretion • regulation of steroid hormone secretion • regulation of biological quality
Gene Ontology	Biological Process	• positive regulation of cell communication • multicellular organismal process • regulation of localization • system process • regulation of cellular process • positive regulation of steroid hormone secretion • regulation of system process • cell communication • regulation of glucocorticoid secretion • localization • positive regulation of cortisol secretion • positive regulation of glucocorticoid secretion • regulation of steroid hormone secretion • regulation of biological quality • regulation of biological process • cortisol secretion • positive regulation of corticosteroid hormone secretion • regulation of hormone levels • lipid transport • regulation of corticosteroid hormone secretion • establishment of localization • regulation of secretion • endocrine hormone secretion • positive regulation of lipid transport • lipid export from cell • regulation of cortisol secretion • positive regulation of multicellular organismal process • glucocorticoid secretion • regulation of endocrine process • corticosteroid hormone secretion • regulation of hormone secretion • transport • signaling • steroid hormone secretion • positive regulation of biological process • regulation of lipid transport • organic hydroxy compound transport • positive regulation of secretion by cell • hormone secretion • secretion by cell • regulation of secretion by cell • positive regulation of hormone secretion • positive regulation of secretion • signal release • regulation of multicellular organismal process • positive regulation of cellular process • regulation of signaling • secretion • regulation of transport • biological regulation • lipid localization • export from cell • cell-cell signaling • positive regulation of lipid localization • endocrine process • positive regulation of transport • regulation of lipid localization • macromolecule localization • hormone transport • regulation of cell communication • cellular process • positive regulation of signaling • response to stimulus • response to chemical • response to xenobiotic stimulus • cellular response to stimulus • G protein-coupled receptor signaling pathway • signal transduction • neuropeptide signaling pathway • response to hormone • response to endogenous stimulus • response to estrogen • positive regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • cell death • positive regulation of apoptotic process • apoptotic process • programmed cell death • regulation of developmental process • epidermis development • molting cycle process • regulation of hair cycle • catagen • hair cycle phase • positive regulation of hair follicle maturation • positive regulation of developmental process • multicellular organism development • regulation of timing of catagen • skin epidermis development • hair follicle development • anatomical structure development • positive regulation of timing of catagen • hair follicle maturation • developmental process • regulation of hair follicle maturation • epithelium development • regulation of multicellular organismal development • biological phase • hair cycle • animal organ development • developmental maturation • tissue development • positive regulation of hair follicle development • skin development • anatomical structure maturation • molting cycle • regulation of hair follicle development • hair cycle process • behavior • feeding behavior • positive regulation of cation transmembrane transport • monoatomic ion transmembrane transport • regulation of transmembrane transporter activity • regulation of monoatomic ion transmembrane transport • positive regulation of large conductance calcium-activated potassium channel activity • monoatomic cation transmembrane transport • positive regulation of molecular function • positive regulation of monoatomic ion transport • positive regulation of transmembrane transport • monoatomic ion transport • positive regulation of monoatomic ion transmembrane transport • monoatomic cation transport • regulation of monoatomic ion transport • positive regulation of cation channel activity • transmembrane transport • regulation of molecular function • regulation of transmembrane transport • positive regulation of transporter activity • positive regulation of ion transmembrane transporter activity • regulation of monoatomic cation transmembrane transport • negative regulation of lymphocyte proliferation • regulation of leukocyte activation • negative regulation of biological process • regulation of cell activation • lymphocyte activation • negative regulation of lymphocyte activation • leukocyte proliferation • leukocyte activation • negative regulation of mononuclear cell proliferation • negative regulation of leukocyte proliferation • lymphocyte proliferation • negative regulation of cellular process • regulation of immune system process • regulation of lymphocyte proliferation • regulation of leukocyte proliferation • negative regulation of cell population proliferation • cell population proliferation • cell activation • negative regulation of cell activation • negative regulation of immune system process • regulation of cell population proliferation • mononuclear cell proliferation • immune system process • regulation of mononuclear cell proliferation • negative regulation of multicellular organismal process • negative regulation of leukocyte activation • regulation of lymphocyte activation • regulation of hormone metabolic process • steroid metabolic process • regulation of steroid metabolic process • regulation of lipid metabolic process • primary metabolic process • hormone metabolic process • regulation of primary metabolic process • glucocorticoid metabolic process • regulation of glucocorticoid metabolic process • metabolic process • regulation of metabolic process • lipid metabolic process • nervous system development • system development • response to immobilization stress • response to stress • response to peptide hormone • response to insulin • response to oxygen-containing compound • response to nitrogen compound • parental behavior • reproductive process • multicellular organismal reproductive process • reproductive behavior • positive regulation of DNA-templated transcription • RNA metabolic process • positive regulation of macromolecule biosynthetic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • positive regulation of metabolic process • DNA-templated transcription • regulation of RNA metabolic process • transcription by RNA polymerase II • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of biosynthetic process • regulation of transcription by RNA polymerase II • regulation of macromolecule metabolic process • positive regulation of transcription by RNA polymerase II • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • positive regulation of RNA metabolic process • regulation of gene expression • biosynthetic process • positive regulation of RNA biosynthetic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • regulation of DNA-templated transcription • establishment of protein localization • nitrogen compound transport • protein localization to extracellular region • peptide secretion • amide transport • intracellular protein localization • establishment of protein localization to extracellular region • protein secretion • peptide transport • protein transport • peptide hormone secretion • insulin secretion • membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • secretory granule • secretory vesicle • cytoplasm • vesicle • extracellular region
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • secretory granule • secretory vesicle • cytoplasm • vesicle • extracellular region • somatodendritic compartment • cell body • neuronal cell body • extracellular space • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • galanin receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • neuropeptide receptor activity • neuropeptide binding • peptide binding • amide binding • peptide hormone binding • hormone binding • neuropeptide signaling pathway • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • polyol metabolic process • organophosphate metabolic process • phosphate-containing compound metabolic process • metabolic process • alcohol metabolic process • small molecule metabolic process • inositol phosphate metabolic process • phosphorus metabolic process • behavior • feeding behavior • galanin-activated signaling pathway • regulation of localization • positive regulation of cation transmembrane transport • transport • monoatomic ion transmembrane transport • positive regulation of biological process • regulation of transmembrane transporter activity • regulation of monoatomic ion transmembrane transport • positive regulation of large conductance calcium-activated potassium channel activity • monoatomic cation transmembrane transport • localization • positive regulation of molecular function • positive regulation of monoatomic ion transport • positive regulation of transmembrane transport • monoatomic ion transport • positive regulation of monoatomic ion transmembrane transport • monoatomic cation transport • positive regulation of cellular process • regulation of transport • regulation of monoatomic ion transport • positive regulation of cation channel activity • establishment of localization • transmembrane transport • regulation of molecular function • regulation of transmembrane transport • positive regulation of transport • positive regulation of transporter activity • positive regulation of ion transmembrane transporter activity • regulation of monoatomic cation transmembrane transport • cell surface receptor signaling pathway • learning or memory • cognition • muscle contraction • muscle system process • phosphatidylinositol metabolic process • glycerophospholipid metabolic process • primary metabolic process • phospholipid metabolic process • glycerolipid metabolic process • lipid metabolic process • positive regulation of DNA-templated transcription • RNA metabolic process • positive regulation of macromolecule biosynthetic process • regulation of primary metabolic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • positive regulation of metabolic process • DNA-templated transcription • regulation of RNA metabolic process • transcription by RNA polymerase II • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of biosynthetic process • regulation of transcription by RNA polymerase II • regulation of macromolecule metabolic process • positive regulation of transcription by RNA polymerase II • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • positive regulation of RNA metabolic process • regulation of gene expression • biosynthetic process • positive regulation of RNA biosynthetic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • regulation of DNA-templated transcription • regulation of metabolic process • plasma membrane bounded cell projection organization • cellular developmental process • cell projection organization • cell development • neuron projection development • nervous system development • cellular component organization • generation of neurons • neurogenesis • neuron differentiation • cell differentiation • neuron development • cellular component organization or biogenesis
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O43603
Sequence	>7XBD_nogp_Chain_R E A V I V P L L F A L I F L V G T V G N T L V L A V L L R G G Q A V S T T N L F I L N L G V A D L C F I L C C V P F Q A T I Y T L D G W V F G S L L C K A V H F L I F L T M H A S S F T L A A V S L D R Y L A I R Y P L H S R E L R T P R N A L A A I G L I W G L S L L F S G P Y L S Y Y R Q S Q L A N L T V C H P A W S A P R R R A M D I C T F V F S Y L L P V L V L G L T Y A R T L R Y L W R A V D P V A A G S G A R R A K R K V T R M I L I V A A L F C L C W M P H H A L I L C V W F G Q F P L T R A T Y A L R I L S H L V S Y A N S C V N P I V Y A L V S K H F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7WQ4	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.6	2022-04-20	doi.org/10.1038/s41467-022-29072-3
	7WQ4 (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		2.6	2022-04-20	doi.org/10.1038/s41467-022-29072-3
	7XJK	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.3	2022-06-29	doi.org/10.1073/pnas.2121465119
	7XJK (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		3.3	2022-06-29	doi.org/10.1073/pnas.2121465119
	7XJL	A	Peptide	Galanin	GAL₂	Homo sapiens	Spexin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.5	2022-06-29	doi.org/10.1073/pnas.2121465119
	7XJL (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Spexin	-		3.5	2022-06-29	doi.org/10.1073/pnas.2121465119
	7XBD	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.11	2022-07-13	doi.org/10.1371/journal.pbio.3001714
	7XBD (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		3.11	2022-07-13	doi.org/10.1371/journal.pbio.3001714

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7XBD_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.