psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:L10	L:L:W2	3.42	No	Yes	0	0	0
2	L:L:W2	R:R:L266	7.97	Yes	No	0	0	1
3	L:L:W2	R:R:T270	8.49	Yes	No	0	0	4
4	L:L:W2	R:R:Y271	5.79	Yes	No	0	0	3
5	L:L:P4	L:L:T3	5.25	No	Yes	0	0	0
6	L:L:T3	R:R:D89	4.34	Yes	No	0	0	4
7	L:L:P4	R:R:L172	3.28	No	No	0	0	1
8	L:L:Q5	R:R:G90	4.93	No	No	0	0	5
9	L:L:Q5	R:R:V174	5.73	No	No	0	0	4
10	L:L:L8	R:R:L169	6.92	No	No	0	0	2
11	L:L:Y9	R:R:I85	9.67	No	No	0	0	5
12	L:L:Y9	R:R:H102	3.27	No	No	1	0	4
13	L:L:Y9	R:R:Y164	8.94	No	Yes	1	0	5
14	L:L:K11	L:L:L10	5.64	No	No	0	0	0
15	L:L:L10	R:R:R274	8.5	No	Yes	0	0	3
16	L:L:G12	R:R:P177	6.09	No	Yes	0	0	4
17	R:R:P29	R:R:V28	3.53	No	No	0	5	6
18	R:R:P29	R:R:T87	6.99	No	No	0	5	4
19	R:R:A83	R:R:F32	5.55	No	No	0	6	7
20	R:R:F32	R:R:Y282	7.22	No	Yes	0	7	7
21	R:R:F36	R:R:T40	6.49	No	No	0	7	6
22	R:R:C286	R:R:V38	5.12	No	No	0	7	6
23	R:R:C286	R:R:G39	3.92	No	No	0	7	8
24	R:R:L72	R:R:N43	10.98	Yes	No	3	8	9
25	R:R:N43	R:R:P289	9.77	No	No	3	9	9
26	R:R:F303	R:R:L45	7.31	No	No	0	7	6
27	R:R:L47	R:R:V69	11.92	No	No	0	7	6
28	R:R:A48	R:R:I306	4.87	No	No	0	3	5
29	R:R:F299	R:R:V49	11.8	Yes	No	0	8	7
30	R:R:F303	R:R:V49	5.24	No	No	0	7	7
31	R:R:L50	R:R:N61	4.12	Yes	No	0	6	7
32	R:R:L51	R:R:L65	4.15	No	No	0	4	6
33	R:R:G53	R:R:I306	3.53	No	No	0	5	5
34	R:R:N61	R:R:Q55	6.6	No	Yes	0	7	6
35	R:R:G302	R:R:Q55	4.93	No	Yes	0	5	6
36	R:R:N61	R:R:S58	8.94	No	No	0	7	8
37	R:R:D122	R:R:T59	5.78	No	Yes	5	8	6
38	R:R:R137	R:R:T59	7.76	Yes	Yes	5	6	6
39	R:R:A142	R:R:T59	5.03	No	Yes	0	7	6
40	R:R:R137	R:R:T60	3.88	Yes	No	0	6	7
41	R:R:L143	R:R:L62	5.54	No	No	0	3	5
42	R:R:F63	R:R:V119	3.93	Yes	No	0	7	9
43	R:R:D122	R:R:F63	8.36	No	Yes	0	8	7
44	R:R:N66	R:R:T115	4.39	No	No	0	9	8
45	R:R:I146	R:R:N66	14.16	No	No	0	7	9
46	R:R:N66	R:R:W150	7.91	No	Yes	0	9	9
47	R:R:G68	R:R:L67	3.42	No	No	0	8	9
48	R:R:L67	R:R:T115	7.37	No	No	0	9	8
49	R:R:L116	R:R:L67	4.15	No	No	0	8	9
50	R:R:G68	R:R:L72	5.13	No	Yes	0	8	8
51	R:R:A70	R:R:W150	5.19	No	Yes	0	8	9
52	R:R:D71	R:R:L72	4.07	No	Yes	0	9	8
53	R:R:D71	R:R:S112	8.83	No	No	0	9	9
54	R:R:L72	R:R:N288	5.49	Yes	No	0	8	9
55	R:R:L72	R:R:P289	4.93	Yes	No	3	8	9
56	R:R:I75	R:R:T108	12.16	No	No	0	7	8
57	R:R:I75	R:R:S285	7.74	No	No	0	7	9
58	R:R:C78	R:R:L104	3.17	No	No	0	7	5
59	R:R:C78	R:R:I105	4.91	No	No	0	7	5
60	R:R:P80	R:R:V79	3.53	No	No	0	8	7
61	R:R:V79	R:R:Y282	17.66	No	Yes	0	7	7
62	R:R:F81	R:R:F93	10.72	No	Yes	0	6	6
63	R:R:F81	R:R:V101	11.8	No	No	0	6	5
64	R:R:I105	R:R:Q82	4.12	No	No	0	5	6
65	R:R:H278	R:R:Q82	11.13	Yes	No	2	5	6
66	R:R:Q82	R:R:Y282	9.02	No	Yes	2	6	7
67	R:R:L88	R:R:T84	10.32	No	No	0	4	3
68	R:R:F93	R:R:T84	7.78	Yes	No	0	6	3
69	R:R:I85	R:R:W91	3.52	No	Yes	0	5	8
70	R:R:Y271	R:R:Y86	3.97	No	Yes	2	3	5
71	R:R:R274	R:R:Y86	8.23	Yes	Yes	2	3	5
72	R:R:I275	R:R:Y86	3.63	No	Yes	2	3	5
73	R:R:H278	R:R:Y86	13.07	Yes	Yes	2	5	5
74	R:R:F93	R:R:W91	13.03	Yes	Yes	0	6	8
75	R:R:C98	R:R:W91	3.92	No	Yes	1	9	8
76	R:R:H102	R:R:W91	5.29	No	Yes	1	4	8
77	R:R:Q166	R:R:W91	4.38	Yes	Yes	0	5	8
78	R:R:C175	R:R:W91	15.67	No	Yes	1	9	8
79	R:R:F93	R:R:L97	4.87	Yes	No	0	6	5
80	R:R:K99	R:R:L96	5.64	No	No	0	6	1
81	R:R:C175	R:R:C98	7.28	No	No	1	9	9
82	R:R:K99	R:R:L161	11.28	No	No	0	6	5
83	R:R:H102	R:R:Y164	13.07	No	Yes	1	4	5
84	R:R:F103	R:R:L161	8.53	No	No	0	6	5
85	R:R:F106	R:R:M109	7.46	No	No	0	4	7
86	R:R:F106	R:R:Y160	21.66	No	Yes	0	4	4
87	R:R:L107	R:R:W150	5.69	No	Yes	0	4	9
88	R:R:L107	R:R:S153	6.01	No	No	0	4	8
89	R:R:M109	R:R:S195	7.67	No	No	0	7	6
90	R:R:M109	R:R:W249	4.65	No	Yes	0	7	9
91	R:R:F114	R:R:H110	3.39	No	Yes	0	6	6
92	R:R:H110	R:R:S153	4.18	Yes	No	0	6	8
93	R:R:F156	R:R:H110	5.66	No	Yes	0	4	6
94	R:R:H110	R:R:S157	6.97	Yes	No	0	6	7
95	R:R:H110	R:R:S195	9.76	Yes	No	0	6	6
96	R:R:A111	R:R:W150	5.19	No	Yes	0	6	9
97	R:R:A111	R:R:S153	3.42	No	No	0	6	8
98	R:R:S113	R:R:S195	4.89	No	No	0	7	6
99	R:R:P199	R:R:S113	7.13	No	No	0	8	7
100	R:R:F245	R:R:S113	3.96	Yes	No	0	9	7
101	R:R:I149	R:R:T115	6.08	No	No	0	7	8
102	R:R:F245	R:R:L116	7.31	Yes	No	0	9	8
103	R:R:L116	R:R:Y292	7.03	No	Yes	0	8	9
104	R:R:A117	R:R:V202	3.39	No	No	0	7	6
105	R:R:V119	R:R:Y292	5.05	No	Yes	0	9	9
106	R:R:S120	R:R:T206	7.99	No	No	0	9	7
107	R:R:S120	R:R:Y207	15.26	No	Yes	0	9	9
108	R:R:D122	R:R:R137	9.53	No	Yes	5	8	6
109	R:R:R123	R:R:Y207	10.29	No	Yes	0	9	9
110	R:R:R123	R:R:Y292	8.23	No	Yes	0	9	9
111	R:R:R128	R:R:Y124	8.23	No	No	0	7	8
112	R:R:R209	R:R:Y124	14.4	No	No	0	4	8
113	R:R:T210	R:R:Y124	6.24	No	No	0	8	8
114	R:R:A126	R:R:R137	6.91	No	Yes	0	8	6
115	R:R:R128	R:R:Y129	12.35	No	No	0	7	6
116	R:R:R128	R:R:Y213	23.66	No	No	0	7	5
117	R:R:S133	R:R:Y129	5.09	No	No	0	6	6
118	R:R:L131	R:R:R134	3.64	No	No	0	6	4
119	R:R:E135	R:R:L136	3.98	No	No	0	3	3
120	R:R:P139	R:R:T138	5.25	No	No	0	2	7
121	R:R:N141	R:R:T138	8.77	No	No	0	4	7
122	R:R:F156	R:R:L152	4.87	No	No	0	4	4
123	R:R:F156	R:R:F194	15	No	No	0	4	4
124	R:R:G158	R:R:P159	4.06	No	No	0	4	7
125	R:R:M187	R:R:P159	5.03	No	No	0	5	7
126	R:R:Y160	R:R:Y163	9.93	Yes	Yes	1	4	4
127	R:R:M187	R:R:Y160	8.38	No	Yes	1	5	4
128	R:R:T191	R:R:Y160	6.24	No	Yes	0	5	4
129	R:R:Y163	R:R:Y164	7.94	Yes	Yes	1	4	5
130	R:R:R184	R:R:Y163	10.29	Yes	Yes	0	4	4
131	R:R:M187	R:R:Y163	4.79	No	Yes	1	5	4
132	R:R:D188	R:R:Y163	6.9	No	Yes	0	5	4
133	R:R:P177	R:R:Y164	9.74	Yes	Yes	0	4	5
134	R:R:A178	R:R:Q165	6.06	No	No	0	4	4
135	R:R:Q166	R:R:T173	7.09	Yes	No	0	5	5
136	R:R:L169	R:R:S167	6.01	No	No	0	2	1
137	R:R:H176	R:R:S167	9.76	Yes	No	0	4	1
138	R:R:Q168	R:R:T173	5.67	No	No	0	3	5
139	R:R:L172	R:R:N171	5.49	No	No	0	1	4
140	R:R:H176	R:R:V174	5.54	Yes	No	0	4	4
141	R:R:H176	R:R:P177	4.58	Yes	Yes	0	4	4
142	R:R:P177	R:R:R184	14.41	Yes	Yes	0	4	4
143	R:R:R183	R:R:W179	13	No	No	0	2	4
144	R:R:P182	R:R:S180	3.56	No	No	0	1	4
145	R:R:R183	R:R:S180	13.18	No	No	0	2	4
146	R:R:R184	R:R:W260	12	Yes	Yes	0	4	4
147	R:R:R185	R:R:W260	10	No	Yes	0	3	4
148	R:R:F261	R:R:R185	5.34	No	No	0	4	3
149	R:R:D188	R:R:I256	4.2	No	No	0	5	6
150	R:R:D188	R:R:W260	7.82	No	Yes	0	5	4
151	R:R:F192	R:R:Y196	4.13	No	No	0	5	8
152	R:R:F192	R:R:H253	10.18	No	No	0	5	8
153	R:R:F192	R:R:L257	4.87	No	No	0	5	6
154	R:R:F194	R:R:V193	5.24	No	No	0	4	4
155	R:R:V200	R:R:Y196	12.62	No	No	0	6	8
156	R:R:L198	R:R:P199	6.57	No	No	0	5	8
157	R:R:F245	R:R:V200	3.93	Yes	No	0	9	6
158	R:R:L201	R:R:L205	5.54	No	No	0	3	4
159	R:R:L203	R:R:Y207	8.21	Yes	Yes	0	8	9
160	R:R:F245	R:R:L203	4.87	Yes	Yes	0	9	8
161	R:R:I238	R:R:Y207	9.67	No	Yes	0	7	9
162	R:R:V241	R:R:Y207	3.79	Yes	Yes	0	8	9
163	R:R:L211	R:R:T235	7.37	No	No	0	4	6
164	R:R:I238	R:R:L211	8.56	No	No	0	7	4
165	R:R:R212	R:R:R216	5.33	No	No	0	4	5
166	R:R:T235	R:R:W215	8.49	No	No	0	6	4
167	R:R:R229	R:R:S225	6.59	No	No	0	4	3
168	R:R:R229	R:R:R232	8.53	No	No	0	4	4
169	R:R:V241	R:R:Y292	5.05	Yes	Yes	0	8	9
170	R:R:C248	R:R:L244	3.17	No	No	0	8	7
171	R:R:L244	R:R:V287	5.96	No	No	0	7	6
172	R:R:L244	R:R:V291	4.47	No	No	0	7	8
173	R:R:C248	R:R:N284	6.3	No	No	0	8	9
174	R:R:H252	R:R:W249	4.23	Yes	Yes	0	7	9
175	R:R:S281	R:R:W249	6.18	No	Yes	0	7	9
176	R:R:N284	R:R:W249	6.78	No	Yes	0	9	9
177	R:R:M250	R:R:P251	3.35	No	No	0	5	9
178	R:R:P251	R:R:S277	3.56	No	No	0	9	6
179	R:R:P251	R:R:V280	5.3	No	No	0	9	8
180	R:R:H252	R:R:H253	5.97	Yes	No	0	7	8
181	R:R:H252	R:R:I256	6.63	Yes	No	0	7	6
182	R:R:H252	R:R:S277	4.18	Yes	No	0	7	6
183	R:R:F264	R:R:L255	7.31	Yes	No	0	5	4
184	R:R:L255	R:R:R274	4.86	No	Yes	0	4	3
185	R:R:V259	R:R:W260	4.9	No	Yes	0	4	4
186	R:R:F264	R:R:V259	5.24	Yes	No	0	5	4
187	R:R:F264	R:R:P265	5.78	Yes	No	0	5	3
188	R:R:F264	R:R:T270	6.49	Yes	No	0	5	4
189	R:R:T267	R:R:T270	6.28	No	No	0	3	4
190	R:R:I275	R:R:Y271	8.46	No	No	2	3	3
191	R:R:H278	R:R:R274	15.8	Yes	Yes	2	5	3
192	R:R:H278	R:R:Y282	4.36	Yes	Yes	2	5	7
193	R:R:S281	R:R:Y282	6.36	No	Yes	0	7	7
194	R:R:N284	R:R:N288	10.9	No	No	0	9	9
195	R:R:A293	R:R:F299	6.93	No	Yes	0	7	8
196	R:R:F299	R:R:L294	4.87	Yes	No	0	8	6
197	R:R:K297	R:R:K301	8.62	No	No	0	4	5
198	R:R:K301	R:R:R304	11.14	No	No	0	5	4
199	R:R:A142	R:R:L62	3.15	No	No	0	7	5
200	R:R:I238	R:R:V234	3.07	No	No	0	7	7
201	R:R:I127	R:R:T210	3.04	No	No	0	8	8
202	R:R:M237	R:R:V241	3.04	No	Yes	0	8	8
203	R:R:M237	R:R:V295	3.04	No	No	0	8	6
204	R:R:F103	R:R:G158	3.01	No	No	0	6	4
205	R:R:L72	R:R:S285	3	Yes	No	0	8	9
206	R:R:L125	R:R:S133	3	No	No	0	5	6
207	R:R:R184	R:R:W179	3	Yes	No	0	4	4
208	R:R:L197	R:R:V193	2.98	No	No	0	4	4
209	R:R:L276	R:R:V280	2.98	No	No	0	6	8
210	R:R:L214	R:R:T210	2.95	No	No	0	7	8
211	R:R:L239	R:R:T235	2.95	No	No	0	5	6
212	R:R:A178	R:R:H176	2.93	No	Yes	0	4	4
213	R:R:I64	R:R:L50	2.85	No	Yes	0	8	6
214	R:R:I275	R:R:L279	2.85	No	No	0	3	5
215	R:R:I290	R:R:L294	2.85	No	No	0	6	6
216	L:L:M7	R:R:L266	2.83	No	No	0	0	1
217	R:R:C190	R:R:F194	2.79	No	No	0	3	4
218	R:R:C258	R:R:F264	2.79	No	Yes	0	4	5
219	R:R:C307	R:R:F303	2.79	No	No	0	6	7
220	R:R:L279	R:R:L31	2.77	No	No	0	5	4
221	R:R:L50	R:R:L65	2.77	Yes	No	0	6	6
222	R:R:A118	R:R:F63	2.77	No	Yes	0	7	7
223	R:R:A145	R:R:F63	2.77	No	Yes	0	5	7
224	L:L:A6	R:R:Y86	2.67	No	Yes	0	0	5
225	R:R:R137	R:R:S133	2.64	Yes	No	0	6	6
226	R:R:R228	R:R:S225	2.64	No	No	0	3	3
227	R:R:F32	R:R:V28	2.62	No	No	0	7	6
228	R:R:F299	R:R:V46	2.62	Yes	No	0	8	9
229	R:R:F93	R:R:V92	2.62	Yes	No	0	6	3
230	R:R:A181	R:R:W260	2.59	No	Yes	0	3	4
231	R:R:F261	R:R:I189	2.51	No	No	0	4	5
232	R:R:F299	R:R:L50	2.44	Yes	Yes	0	8	6
233	R:R:F103	R:R:L154	2.44	No	No	0	6	4
234	R:R:G53	R:R:G54	2.11	No	No	4	5	6
235	R:R:R232	R:R:W215	2	No	No	0	4	4
236	R:R:G42	R:R:V41	1.84	No	No	0	7	4
237	R:R:G68	R:R:V46	1.84	No	No	0	8	9
238	R:R:C73	R:R:C77	1.82	No	No	0	7	4
239	R:R:P139	R:R:T59	1.75	No	Yes	0	2	6
240	R:R:G302	R:R:K301	1.74	No	No	0	5	5
241	R:R:G39	R:R:L76	1.71	No	No	0	8	4
242	R:R:G151	R:R:L154	1.71	No	No	0	4	4
243	R:R:C246	R:R:V200	1.71	No	No	0	5	6
244	R:R:G204	R:R:L203	1.71	No	Yes	0	4	8
245	R:R:G39	R:R:N43	1.7	No	No	0	8	9
246	L:L:A6	L:L:T3	1.68	No	Yes	0	0	0
247	R:R:C286	R:R:I35	1.64	No	No	0	7	7
248	R:R:G53	R:R:Q55	1.64	No	Yes	4	5	6
249	R:R:G54	R:R:Q55	1.64	No	Yes	4	6	6
250	R:R:G94	R:R:Q166	1.64	No	Yes	0	7	5
251	R:R:A100	R:R:K99	1.61	No	No	0	4	6
252	R:R:V46	R:R:V69	1.6	No	No	0	9	6
253	R:R:T206	R:R:V202	1.59	No	No	0	7	6
254	R:R:C246	R:R:L247	1.59	No	No	0	5	5
255	R:R:A242	R:R:L203	1.58	No	Yes	0	8	8
256	R:R:A243	R:R:L247	1.58	No	No	0	5	5
257	R:R:T40	R:R:T44	1.57	No	No	0	6	4
258	R:R:I27	R:R:V28	1.54	No	No	0	5	6
259	R:R:I240	R:R:V241	1.54	No	Yes	0	6	8
260	R:R:I240	R:R:V291	1.54	No	No	0	6	8
261	L:L:A13	L:L:Q14	1.52	No	No	0	0	0
262	R:R:G226	R:R:R229	1.5	No	No	0	3	4
263	R:R:L45	R:R:V41	1.49	No	No	0	6	4
264	R:R:L76	R:R:T40	1.47	No	No	0	4	6
265	R:R:L121	R:R:T206	1.47	No	No	0	6	7
266	L:L:N1	L:L:T3	1.46	No	Yes	0	0	0
267	R:R:Q166	R:R:S95	1.44	Yes	No	0	5	3
268	R:R:P130	R:R:Y129	1.39	No	No	0	8	6
269	R:R:H298	R:R:S296	1.39	No	No	0	5	8
270	R:R:L125	R:R:L136	1.38	No	No	0	5	3
271	R:R:A144	R:R:R140	1.38	No	No	0	2	4
272	R:R:L255	R:R:L273	1.38	No	No	0	4	4
273	R:R:A269	R:R:R268	1.38	No	No	0	2	1
274	L:L:K11	L:L:Q14	1.36	No	No	0	0	0
275	R:R:F299	R:R:S296	1.32	Yes	No	0	8	8
276	R:R:F74	R:R:T108	1.3	No	No	0	7	8
277	R:R:R140	R:R:T138	1.29	No	No	0	4	7
278	R:R:R268	R:R:T267	1.29	No	No	0	1	3
279	R:R:I306	R:R:R52	1.25	No	No	0	5	4
280	R:R:S162	R:R:W179	1.24	No	No	0	4	4
281	R:R:K297	R:R:R300	1.24	No	No	0	4	8
282	R:R:K231	R:R:W215	1.16	No	No	0	7	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:W2	6.4175	4	0	0
2	L:L:T3	3.1825	4	0	0
3	R:R:L50	3.045	4	0	6
4	R:R:Q55	3.7025	4	4	6
5	R:R:T59	5.08	4	5	6
6	R:R:F63	4.4575	4	0	7
7	R:R:L72	5.6	6	3	8
8	R:R:Y86	6.314	5	2	5
9	R:R:W91	7.635	6	1	8
10	R:R:F93	7.804	5	0	6
11	R:R:H110	5.992	5	0	6
12	R:R:R137	6.144	5	5	6
13	R:R:W150	5.995	4	0	9
14	R:R:Y160	11.5525	4	1	4
15	R:R:Y163	7.97	5	1	4
16	R:R:Y164	9.9225	4	1	5
17	R:R:Q166	3.6375	4	0	5
18	R:R:H176	5.7025	4	0	4
19	R:R:P177	8.705	4	0	4
20	R:R:R184	9.925	4	0	4
21	R:R:L203	4.0925	4	0	8
22	R:R:Y207	9.444	5	0	9
23	R:R:V241	3.355	4	0	8
24	R:R:F245	5.0175	4	0	9
25	R:R:W249	5.46	4	0	9
26	R:R:H252	5.2525	4	0	7
27	R:R:W260	7.462	5	0	4
28	R:R:F264	5.522	5	0	5
29	R:R:R274	9.3475	4	2	3
30	R:R:H278	11.09	4	2	5
31	R:R:Y282	8.924	5	2	7
32	R:R:Y292	6.34	4	0	9
33	R:R:F299	4.99667	6	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:L10	L:L:W2	11.6572	3.42	No	Yes	0	0	0
2	L:L:W2	R:R:T270	18.0684	8.49	Yes	No	0	0	4
3	L:L:W2	R:R:Y271	11.7538	5.79	Yes	No	0	0	3
4	L:L:L10	R:R:R274	16.6138	8.5	No	Yes	0	0	3
5	L:L:A6	R:R:Y86	15.3867	2.67	No	Yes	0	0	5
6	L:L:A6	L:L:T3	13.229	1.68	No	Yes	0	0	0
7	R:R:F264	R:R:T270	26.6993	6.49	Yes	No	0	5	4
8	R:R:F264	R:R:V259	47.1391	5.24	Yes	No	0	5	4
9	R:R:V259	R:R:W260	50.1586	4.9	No	Yes	0	4	4
10	R:R:R184	R:R:W260	38.198	12	Yes	Yes	0	4	4
11	R:R:P177	R:R:R184	37.0192	14.41	Yes	Yes	0	4	4
12	R:R:H176	R:R:P177	42.6168	4.58	Yes	Yes	0	4	4
13	R:R:H176	R:R:V174	14.3251	5.54	Yes	No	0	4	4
14	R:R:L255	R:R:R274	24.3968	4.86	No	Yes	0	4	3
15	R:R:F264	R:R:L255	23.4317	7.31	Yes	No	0	5	4
16	R:R:H176	R:R:S167	14.3251	9.76	Yes	No	0	4	1
17	R:R:R184	R:R:Y163	47.5941	10.29	Yes	Yes	0	4	4
18	R:R:Y163	R:R:Y164	66.2967	7.94	Yes	Yes	1	4	5
19	R:R:D188	R:R:W260	46.7806	7.82	No	Yes	0	5	4
20	R:R:D188	R:R:Y163	46.0982	6.9	No	Yes	0	5	4
21	R:R:P177	R:R:Y164	27.3887	9.74	Yes	Yes	0	4	5
22	R:R:H102	R:R:Y164	45.9465	13.07	No	Yes	1	4	5
23	R:R:H278	R:R:R274	27.106	15.8	Yes	Yes	2	5	3
24	R:R:H278	R:R:Y282	50.2689	4.36	Yes	Yes	2	5	7
25	R:R:F32	R:R:Y282	15.2971	7.22	No	Yes	0	7	7
26	R:R:F32	R:R:V28	10.2509	2.62	No	No	0	7	6
27	R:R:S281	R:R:Y282	70.8259	6.36	No	Yes	0	7	7
28	R:R:S281	R:R:W249	72.5079	6.18	No	Yes	0	7	9
29	R:R:N284	R:R:W249	87.226	6.78	No	Yes	0	9	9
30	R:R:N284	R:R:N288	78.726	10.9	No	No	0	9	9
31	R:R:L72	R:R:N288	78.078	5.49	Yes	No	0	8	9
32	R:R:L72	R:R:N43	23.5075	10.98	Yes	No	3	8	9
33	R:R:G39	R:R:N43	21.0051	1.7	No	No	0	8	9
34	R:R:G39	R:R:L76	10.6094	1.71	No	No	0	8	4
35	R:R:G68	R:R:L72	68.937	5.13	No	Yes	0	8	8
36	R:R:G68	R:R:V46	78.3538	1.84	No	No	0	8	9
37	R:R:F299	R:R:V46	71.5773	2.62	Yes	No	0	8	9
38	R:R:F299	R:R:V49	15.7797	11.8	Yes	No	0	8	7
39	R:R:F303	R:R:V49	13.1945	5.24	No	No	0	7	7
40	R:R:F299	R:R:L50	43.451	2.44	Yes	Yes	0	8	6
41	R:R:L50	R:R:N61	33.5999	4.12	Yes	No	0	6	7
42	R:R:N61	R:R:Q55	28.5813	6.6	No	Yes	0	7	6
43	R:R:G53	R:R:Q55	10.5543	1.64	No	Yes	4	5	6
44	R:R:G302	R:R:Q55	13.1945	4.93	No	Yes	0	5	6
45	R:R:M109	R:R:W249	77.6299	4.65	No	Yes	0	7	9
46	R:R:M109	R:R:S195	100	7.67	No	No	0	7	6
47	R:R:S113	R:R:S195	82.228	4.89	No	No	0	7	6
48	R:R:F245	R:R:S113	80.9872	3.96	Yes	No	0	9	7
49	R:R:F245	R:R:L116	66.214	7.31	Yes	No	0	9	8
50	R:R:L116	R:R:Y292	78.8019	7.03	No	Yes	0	8	9
51	R:R:V119	R:R:Y292	67.3445	5.05	No	Yes	0	9	9
52	R:R:F63	R:R:V119	65.3109	3.93	Yes	No	0	7	9
53	R:R:D122	R:R:F63	59.3065	8.36	No	Yes	0	8	7
54	R:R:D122	R:R:T59	20.6466	5.78	No	Yes	5	8	6
55	R:R:D122	R:R:R137	36.5573	9.53	No	Yes	5	8	6
56	R:R:H110	R:R:S195	32.8071	9.76	Yes	No	0	6	6
57	R:R:H110	R:R:S153	15.0627	4.18	Yes	No	0	6	8
58	R:R:G68	R:R:L67	45.9948	3.42	No	No	0	8	9
59	R:R:L67	R:R:T115	11.6986	7.37	No	No	0	9	8
60	R:R:L72	R:R:S285	10.6094	3	Yes	No	0	8	9
61	R:R:H102	R:R:W91	43.4027	5.29	No	Yes	1	4	8
62	R:R:F93	R:R:W91	20.7018	13.03	Yes	Yes	0	6	8
63	R:R:Q166	R:R:W91	15.0558	4.38	Yes	Yes	0	5	8
64	R:R:M187	R:R:P159	20.2192	5.03	No	No	0	5	7
65	R:R:G158	R:R:P159	18.027	4.06	No	No	0	4	7
66	R:R:F103	R:R:G158	15.821	3.01	No	No	0	6	4
67	R:R:F106	R:R:M109	85.3302	7.46	No	No	0	4	7
68	R:R:Y160	R:R:Y163	71.1705	9.93	Yes	Yes	1	4	4
69	R:R:F156	R:R:H110	13.1876	5.66	No	Yes	0	4	6
70	R:R:F245	R:R:L203	43.127	4.87	Yes	Yes	0	9	8
71	R:R:L203	R:R:Y207	38.7012	8.21	Yes	Yes	0	8	9
72	R:R:S120	R:R:Y207	16.469	15.26	No	Yes	0	9	9
73	R:R:S120	R:R:T206	13.2014	7.99	No	No	0	9	7
74	R:R:R137	R:R:S133	30.7459	2.64	Yes	No	0	6	6
75	R:R:S133	R:R:Y129	21.4808	5.09	No	No	0	6	6
76	R:R:R128	R:R:Y129	16.7655	12.35	No	No	0	7	6
77	R:R:R128	R:R:Y124	12.1605	8.23	No	No	0	7	8
78	R:R:P139	R:R:T59	12.1605	1.75	No	Yes	0	2	6
79	R:R:F106	R:R:Y160	84.5581	21.66	No	Yes	0	4	4
80	R:R:R184	R:R:W179	15.5039	3	Yes	No	0	4	4
81	R:R:R185	R:R:W260	11.285	10	No	Yes	0	3	4
82	R:R:D188	R:R:I256	60.8093	4.2	No	No	0	5	6
83	R:R:H252	R:R:W249	58.3207	4.23	Yes	Yes	0	7	9
84	R:R:H252	R:R:I256	61.7951	6.63	Yes	No	0	7	6
85	R:R:H252	R:R:H253	16.9378	5.97	Yes	No	0	7	8
86	R:R:F192	R:R:H253	15.9176	10.18	No	No	0	5	8
87	R:R:F192	R:R:Y196	15.0283	4.13	No	No	0	5	8
88	R:R:F245	R:R:V200	18.027	3.93	Yes	No	0	9	6
89	R:R:V200	R:R:Y196	14.9662	12.62	No	No	0	6	8
90	R:R:I238	R:R:Y207	38.7633	9.67	No	Yes	0	7	9
91	R:R:C248	R:R:N284	11.5263	6.3	No	No	0	8	9
92	R:R:I238	R:R:L211	32.4073	8.56	No	No	0	7	4
93	R:R:L211	R:R:T235	29.2086	7.37	No	No	0	4	6
94	R:R:T235	R:R:W215	22.7561	8.49	No	No	0	6	4
95	R:R:R232	R:R:W215	16.4553	2	No	No	0	4	4
96	R:R:R229	R:R:R232	13.2014	8.53	No	No	0	4	4
97	R:R:H252	R:R:S277	12.126	4.18	Yes	No	0	7	6
98	R:R:T267	R:R:T270	20.7156	6.28	No	No	0	3	4
99	R:R:G302	R:R:K301	10.5818	1.74	No	No	0	5	5
100	R:R:R268	R:R:T267	13.8219	1.29	No	No	0	1	3
101	R:R:H278	R:R:Y86	23.9556	13.07	Yes	Yes	2	5	5
102	R:R:R123	R:R:Y292	13.7254	8.23	No	Yes	0	9	9
103	R:R:R123	R:R:Y207	13.2428	10.29	No	Yes	0	9	9
104	R:R:M187	R:R:Y160	12.4707	8.38	No	Yes	1	5	4
105	R:R:L116	R:R:L67	46.3877	4.15	No	No	0	8	9
106	R:R:V241	R:R:Y292	17.7926	5.05	Yes	Yes	0	8	9
107	R:R:V241	R:R:Y207	15.1592	3.79	Yes	Yes	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:W2	R:R:L266	7.97	0	Yes	No	0	1	0	1
L:L:W2	R:R:T270	8.49	0	Yes	No	0	4	0	1
L:L:W2	R:R:Y271	5.79	0	Yes	No	0	3	0	1
L:L:T3	R:R:D89	4.34	0	Yes	No	0	4	0	1
L:L:P4	R:R:L172	3.28	0	No	No	0	1	0	1
L:L:Q5	R:R:G90	4.93	0	No	No	0	5	0	1
L:L:Q5	R:R:V174	5.73	0	No	No	0	4	0	1
L:L:L8	R:R:L169	6.92	0	No	No	0	2	0	1
L:L:Y9	R:R:I85	9.67	1	No	No	0	5	0	1
L:L:Y9	R:R:H102	3.27	1	No	No	0	4	0	1
L:L:Y9	R:R:Y164	8.94	1	No	Yes	0	5	0	1
L:L:L10	R:R:R274	8.5	0	No	Yes	0	3	0	1
L:L:G12	R:R:P177	6.09	0	No	Yes	0	4	0	1
R:R:I85	R:R:W91	3.52	0	No	Yes	5	8	1	2
R:R:Y271	R:R:Y86	3.97	2	No	Yes	3	5	1	1
R:R:R274	R:R:Y86	8.23	2	Yes	Yes	3	5	1	1
R:R:I275	R:R:Y86	3.63	2	No	Yes	3	5	2	1
R:R:H278	R:R:Y86	13.07	2	Yes	Yes	5	5	2	1
R:R:H102	R:R:W91	5.29	1	No	Yes	4	8	1	2
R:R:H102	R:R:Y164	13.07	1	No	Yes	4	5	1	1
R:R:Y163	R:R:Y164	7.94	1	Yes	Yes	4	5	2	1
R:R:R184	R:R:Y163	10.29	0	Yes	Yes	4	4	2	2
R:R:P177	R:R:Y164	9.74	0	Yes	Yes	4	5	1	1
R:R:L169	R:R:S167	6.01	0	No	No	2	1	1	2
R:R:H176	R:R:S167	9.76	0	Yes	No	4	1	2	2
R:R:L172	R:R:N171	5.49	0	No	No	1	4	1	2
R:R:H176	R:R:V174	5.54	0	Yes	No	4	4	2	1
R:R:H176	R:R:P177	4.58	0	Yes	Yes	4	4	2	1
R:R:P177	R:R:R184	14.41	0	Yes	Yes	4	4	1	2
R:R:F264	R:R:L255	7.31	0	Yes	No	5	4	2	2
R:R:L255	R:R:R274	4.86	0	No	Yes	4	3	2	1
R:R:F264	R:R:T270	6.49	0	Yes	No	5	4	2	1
R:R:T267	R:R:T270	6.28	0	No	No	3	4	2	1
R:R:I275	R:R:Y271	8.46	2	No	No	3	3	2	1
R:R:H278	R:R:R274	15.8	2	Yes	Yes	5	3	2	1
L:L:M7	R:R:L266	2.83	0	No	No	0	1	0	1
L:L:A6	R:R:Y86	2.67	0	No	Yes	0	5	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7XJL_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.17
Number of Linked Nodes	264
Number of Links	282
Number of Hubs	33
Number of Links mediated by Hubs	127
Number of Communities	5
Number of Nodes involved in Communities	25
Number of Links involved in Communities	29

Path Summary
Number Of Nodes in MetaPath	108
Number Of Links MetaPath	107
Number of Shortest Paths	52740
Length Of Smallest Path	3
Average Path Length	13.2196
Length of Longest Path	27
Minimum Path Strength	1.335
Average Path Strength	6.57702
Maximum Path Strength	18.005
Minimum Path Correlation	0.7
Average Path Correlation	0.924236
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	51.3417
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.9521
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• response to nutrient levels • regulation of response to nutrient levels • regulation of biological process • negative regulation of response to food • response to stimulus • negative regulation of response to nutrient levels • negative regulation of response to stimulus • biological regulation • negative regulation of biological process • negative regulation of appetite • regulation of response to food • regulation of response to stimulus • response to food • response to chemical • regulation of biological quality • regulation of appetite • regulation of localization • multicellular organismal process • system process • renal sodium excretion • inorganic ion homeostasis • regulation of renal system process • transport • homeostatic process • regulation of system process • negative regulation of transport • localization • negative regulation of secretion • monoatomic ion homeostasis • negative regulation of renal sodium excretion • regulation of multicellular organismal process • monoatomic cation homeostasis • excretion • renal system process • sodium ion homeostasis • regulation of transport • secretion • renal tubular secretion • establishment of localization • regulation of secretion • regulation of renal sodium excretion • chemical homeostasis • negative regulation of multicellular organismal process • regulation of excretion • import into cell • organic anion transport • carboxylic acid transport • lipid localization • lipid transport • organic acid transport • monocarboxylic acid transport • fatty acid transport • lipid import into cell • macromolecule localization • long-chain fatty acid import into cell • long-chain fatty acid transport • nervous system process • sensory perception of pain • regulation of nervous system process • sensory perception • regulation of sensory perception • regulation of sensory perception of pain • heart process • negative regulation of heart rate • regulation of heart contraction • negative regulation of blood circulation • negative regulation of heart contraction • circulatory system process • regulation of blood circulation • heart contraction • blood circulation • regulation of heart rate • positive regulation of systemic arterial blood pressure • regulation of systemic arterial blood pressure • regulation of blood pressure • positive regulation of blood pressure • gastro-intestinal system smooth muscle contraction • positive regulation of smooth muscle contraction • positive regulation of biological process • muscle contraction • muscle system process • regulation of muscle system process • positive regulation of gastro-intestinal system smooth muscle contraction • regulation of gastro-intestinal system smooth muscle contraction • smooth muscle contraction • regulation of smooth muscle contraction • regulation of muscle contraction • positive regulation of muscle contraction • positive regulation of multicellular organismal process • membrane-bounded organelle • intracellular anatomical structure • dense core granule • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • secretory granule • secretory vesicle • cytoplasm • vesicle
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular anatomical structure • dense core granule • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • organelle • secretory granule • secretory vesicle • cytoplasm • vesicle • transport vesicle • extracellular region • extracellular space • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • galanin receptor activity • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • neuropeptide receptor activity • neuropeptide binding • peptide binding • amide binding • peptide hormone binding • hormone binding • neuropeptide signaling pathway • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • polyol metabolic process • organophosphate metabolic process • phosphate-containing compound metabolic process • metabolic process • alcohol metabolic process • small molecule metabolic process • inositol phosphate metabolic process • phosphorus metabolic process • behavior • feeding behavior • galanin-activated signaling pathway • regulation of localization • positive regulation of cation transmembrane transport • localization • positive regulation of monoatomic ion transport • positive regulation of monoatomic ion transmembrane transport • monoatomic cation transport • regulation of potassium ion transmembrane transporter activity • regulation of monoatomic ion transport • inorganic ion transmembrane transport • regulation of potassium ion transmembrane transport • positive regulation of cation channel activity • establishment of localization • regulation of cation channel activity • inorganic cation transmembrane transport • transmembrane transport • regulation of molecular function • regulation of transmembrane transport • potassium ion transport • regulation of potassium ion transport • transport • monoatomic ion transmembrane transport • positive regulation of biological process • regulation of transmembrane transporter activity • potassium ion transmembrane transport • regulation of monoatomic ion transmembrane transport • positive regulation of large conductance calcium-activated potassium channel activity • metal ion transport • regulation of transporter activity • monoatomic cation transmembrane transport • positive regulation of molecular function • positive regulation of transmembrane transport • monoatomic ion transport • regulation of metal ion transport • positive regulation of cellular process • regulation of monoatomic ion transmembrane transporter activity • regulation of transport • positive regulation of potassium ion transport • positive regulation of transport • positive regulation of transporter activity • positive regulation of potassium ion transmembrane transport • positive regulation of ion transmembrane transporter activity • regulation of monoatomic cation transmembrane transport • positive regulation of potassium ion transmembrane transporter activity • cell surface receptor signaling pathway • learning or memory • cognition • muscle contraction • muscle system process • phosphatidylinositol metabolic process • glycerophospholipid metabolic process • primary metabolic process • phospholipid metabolic process • glycerolipid metabolic process • lipid metabolic process • positive regulation of DNA-templated transcription • RNA metabolic process • positive regulation of macromolecule biosynthetic process • regulation of primary metabolic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • positive regulation of metabolic process • DNA-templated transcription • regulation of RNA metabolic process • transcription by RNA polymerase II • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of biosynthetic process • regulation of transcription by RNA polymerase II • positive regulation of nucleobase-containing compound metabolic process • regulation of macromolecule metabolic process • positive regulation of transcription by RNA polymerase II • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • positive regulation of RNA metabolic process • regulation of gene expression • biosynthetic process • positive regulation of RNA biosynthetic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • regulation of DNA-templated transcription • regulation of metabolic process • plasma membrane bounded cell projection organization • cellular developmental process • cell projection organization • cell development • neuron projection development • nervous system development • cellular component organization • generation of neurons • neurogenesis • neuron differentiation • cell differentiation • neuron development • cellular component organization or biogenesis
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O43603
Sequence	>7XJL_nogp_Chain_R P E A V I V P L L F A L I F L V G T V G N T L V L A V L L R G G Q A V S T T N L F I L N L G V A D L C F I L C C V P F Q A T I Y T L D G W V F G S L L C K A V H F L I F L T M H A S S F T L A A V S L D R Y L A I R Y P L H S R E L R T P R N A L A A I G L I W G L S L L F S G P Y L S Y Y Q Q S Q L A N L T V C H P A W S A P R R R A M D I C T F V F S Y L L P V L V L G L T Y A R T L R Y L W R G S G A R R A K R K V T R M I L I V A A L F C L C W M P H H A L I L C V W F G Q F P L T R A T Y A L R I L S H L V S Y A N S C V N P I V Y A L V S K H F R K G F R T I C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XBD	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.11	2022-07-13	10.1371/journal.pbio.3001714
	7XBD (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		3.11	2022-07-13	10.1371/journal.pbio.3001714
	7XJL	A	Peptide	Galanin	GAL₂	Homo sapiens	Spexin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.5	2022-06-29	10.1073/pnas.2121465119
	7XJL (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Spexin	-		3.5	2022-06-29	10.1073/pnas.2121465119
	7XJK	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.3	2022-06-29	10.1073/pnas.2121465119
	7XJK (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		3.3	2022-06-29	10.1073/pnas.2121465119
	7WQ4	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.6	2022-04-20	10.1038/s41467-022-29072-3
	7WQ4 (No Gprot)	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-		2.6	2022-04-20	10.1038/s41467-022-29072-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7XJL_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.