psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:P11	4.33	Yes	No	0
2	R:R:F14	R:R:N174	13.29	Yes	No	0
3	R:R:F14	R:R:I176	3.77	Yes	Yes	0
4	R:R:L15	R:R:N174	2.75	No	No	0
5	R:R:K82	R:R:L16	2.82	No	No	4
6	R:R:I94	R:R:L16	2.85	No	No	4
7	R:R:I176	R:R:L16	5.71	Yes	No	0
8	R:R:I175	R:R:V17	3.07	No	No	0
9	R:R:I19	R:R:P20	3.39	Yes	No	0
10	R:R:I19	R:R:L22	7.14	Yes	No	0
11	R:R:H26	R:R:I19	2.65	No	Yes	0
12	R:R:I19	R:R:Y273	4.84	Yes	Yes	0
13	R:R:I19	R:R:L277	2.85	Yes	No	0
14	R:R:G21	R:R:Y273	5.79	No	Yes	0
15	R:R:I29	R:R:L22	2.85	No	No	0
16	R:R:E23	R:R:H26	4.92	No	No	0
17	R:R:S24	R:R:V25	3.23	No	No	0
18	R:R:V25	R:R:W28	6.13	No	No	0
19	R:R:I27	R:R:W88	4.7	No	No	0
20	R:R:F87	R:R:S30	10.57	Yes	No	0
21	R:R:I31	R:R:P32	6.77	No	No	0
22	R:R:F33	R:R:M83	9.95	Yes	Yes	2
23	R:R:F33	R:R:F87	5.36	Yes	Yes	2
24	R:R:F33	R:R:N280	6.04	Yes	Yes	2
25	R:R:F33	R:R:L284	3.65	Yes	Yes	2
26	R:R:C34	R:R:L84	6.35	No	No	0
27	R:R:M36	R:R:V285	4.56	No	No	0
28	R:R:M288	R:R:M36	2.89	No	No	0
29	R:R:T77	R:R:Y37	9.99	No	No	0
30	R:R:I80	R:R:Y37	13.3	No	No	0
31	R:R:G43	R:R:P291	4.06	No	No	0
32	R:R:A69	R:R:N44	3.13	No	Yes	0
33	R:R:D72	R:R:N44	9.42	No	Yes	0
34	R:R:L73	R:R:N44	12.36	No	Yes	0
35	R:R:N44	R:R:P291	4.89	Yes	No	0
36	R:R:F49	R:R:S45	6.61	No	No	0
37	R:R:L47	R:R:L65	2.77	No	No	0
38	R:R:A69	R:R:L47	4.73	No	No	0
39	R:R:L57	R:R:Y62	17.58	No	No	0
40	R:R:H58	R:R:Y63	9.8	No	No	0
41	R:R:E59	R:R:P60	4.72	No	Yes	1
42	R:R:E59	R:R:Y134	7.86	No	Yes	1
43	R:R:F64	R:R:P60	2.89	Yes	Yes	1
44	R:R:P60	R:R:Y134	9.74	Yes	Yes	1
45	R:R:L138	R:R:P60	4.93	Yes	Yes	1
46	R:R:I143	R:R:P60	5.08	Yes	Yes	1
47	R:R:D123	R:R:M61	4.16	No	No	0
48	R:R:M61	R:R:Y294	3.59	No	Yes	0
49	R:R:A119	R:R:F64	2.77	No	Yes	0
50	R:R:F64	R:R:M120	3.73	Yes	No	1
51	R:R:D123	R:R:F64	5.97	No	Yes	0
52	R:R:F64	R:R:I143	3.77	Yes	Yes	1
53	R:R:L65	R:R:Y294	18.76	No	Yes	0
54	R:R:M67	R:R:T71	4.52	No	Yes	3
55	R:R:M112	R:R:M67	2.89	Yes	No	3
56	R:R:M67	R:R:V116	4.56	No	No	0
57	R:R:E113	R:R:L68	2.65	No	No	0
58	R:R:F109	R:R:T71	3.89	Yes	Yes	3
59	R:R:M112	R:R:T71	6.02	Yes	Yes	3
60	R:R:E113	R:R:T71	2.82	No	Yes	0
61	R:R:D72	R:R:E113	5.2	No	No	0
62	R:R:D72	R:R:P287	9.66	No	No	0
63	R:R:L73	R:R:S76	3	No	No	0
64	R:R:L73	R:R:T77	2.95	No	No	0
65	R:R:F109	R:R:V74	6.55	Yes	No	0
66	R:R:I106	R:R:L75	4.28	No	No	0
67	R:R:F109	R:R:L75	8.53	Yes	No	0
68	R:R:I106	R:R:T79	4.56	No	No	2
69	R:R:T79	R:R:Y180	6.24	No	Yes	2
70	R:R:I80	R:R:P81	3.39	No	No	0
71	R:R:I80	R:R:L284	2.85	No	Yes	0
72	R:R:I86	R:R:K82	2.91	No	No	0
73	R:R:I94	R:R:K82	2.91	No	No	4
74	R:R:F87	R:R:M83	11.2	Yes	Yes	2
75	R:R:M83	R:R:T179	15.05	Yes	No	2
76	R:R:M83	R:R:N280	8.41	Yes	Yes	2
77	R:R:L84	R:R:W88	3.42	No	No	0
78	R:R:I86	R:R:K92	10.18	No	No	0
79	R:R:F89	R:R:L91	3.65	No	No	0
80	R:R:A98	R:R:I94	3.25	No	No	0
81	R:R:F96	R:R:L100	9.74	No	No	0
82	R:R:C99	R:R:M103	3.24	No	Yes	5
83	R:R:C181	R:R:C99	7.28	No	No	5
84	R:R:Q102	R:R:Y180	3.38	No	Yes	0
85	R:R:C181	R:R:M103	3.24	No	Yes	5
86	R:R:H183	R:R:M103	3.94	Yes	Yes	0
87	R:R:M103	R:R:V186	3.04	Yes	No	0
88	R:R:F104	R:R:S108	2.64	No	No	3
89	R:R:F104	R:R:V158	6.55	No	No	3
90	R:R:F104	R:R:P162	5.78	No	No	0
91	R:R:F105	R:R:F109	18.22	No	Yes	0
92	R:R:I106	R:R:Y180	3.63	No	Yes	2
93	R:R:E182	R:R:H107	6.15	Yes	No	0
94	R:R:H107	R:R:H183	3.58	No	Yes	0
95	R:R:F109	R:R:S108	2.64	Yes	No	3
96	R:R:S108	R:R:V158	4.85	No	No	3
97	R:R:F109	R:R:M112	3.73	Yes	Yes	3
98	R:R:G111	R:R:I208	3.53	No	No	0
99	R:R:M112	R:R:V151	4.56	Yes	No	0
100	R:R:I208	R:R:S114	6.19	No	No	0
101	R:R:D212	R:R:S114	5.89	Yes	No	0
102	R:R:L117	R:R:V249	2.98	No	No	0
103	R:R:D212	R:R:L118	12.21	Yes	No	0
104	R:R:L118	R:R:L215	4.15	No	No	0
105	R:R:H246	R:R:M120	6.57	Yes	No	1
106	R:R:M120	R:R:Y294	4.79	No	Yes	1
107	R:R:A121	R:R:H246	2.93	No	Yes	0
108	R:R:F122	R:R:Y125	3.09	No	Yes	0
109	R:R:D123	R:R:Y134	3.45	No	Yes	0
110	R:R:A127	R:R:R124	4.15	No	Yes	0
111	R:R:I128	R:R:R124	10.02	No	Yes	0
112	R:R:R124	R:R:T242	5.17	Yes	No	0
113	R:R:C243	R:R:R124	4.18	No	Yes	0
114	R:R:C129	R:R:Y125	6.72	No	Yes	0
115	R:R:I223	R:R:Y125	6.04	No	Yes	0
116	R:R:I137	R:R:V126	3.07	No	No	1
117	R:R:L138	R:R:V126	4.47	Yes	No	1
118	R:R:A127	R:R:Y134	2.67	No	Yes	0
119	R:R:I128	R:R:I223	11.77	No	No	0
120	R:R:I128	R:R:L240	2.85	No	No	0
121	R:R:C129	R:R:Y130	2.69	No	No	0
122	R:R:L132	R:R:R133	3.64	No	No	0
123	R:R:L138	R:R:Y134	10.55	Yes	Yes	1
124	R:R:T135	R:R:T136	3.14	No	No	0
125	R:R:I137	R:R:L138	8.56	No	Yes	1
126	R:R:K141	R:R:N140	11.19	No	No	0
127	R:R:G144	R:R:I143	3.53	No	Yes	0
128	R:R:G147	R:R:I146	3.53	No	No	0
129	R:R:I159	R:R:V155	3.07	No	No	0
130	R:R:L157	R:R:L207	2.77	No	No	0
131	R:R:I159	R:R:P160	3.39	No	No	0
132	R:R:P160	R:R:Y200	4.17	No	Yes	0
133	R:R:F161	R:R:H183	14.71	No	Yes	0
134	R:R:F161	R:R:G201	3.01	No	No	0
135	R:R:F161	R:R:V204	2.62	No	No	0
136	R:R:F163	R:R:R167	17.1	No	No	0
137	R:R:L164	R:R:N197	8.24	No	No	0
138	R:R:L165	R:R:V186	2.98	No	No	0
139	R:R:K166	R:R:R167	8.66	No	No	0
140	R:R:I176	R:R:P177	3.39	Yes	No	0
141	R:R:H178	R:R:T179	4.11	Yes	No	2
142	R:R:H178	R:R:Y180	9.8	Yes	Yes	2
143	R:R:E182	R:R:H178	4.92	Yes	Yes	2
144	R:R:H178	R:R:I276	6.63	Yes	No	0
145	R:R:N280	R:R:T179	5.85	Yes	No	2
146	R:R:E182	R:R:Y180	13.47	Yes	Yes	2
147	R:R:L283	R:R:Y180	8.21	No	Yes	0
148	R:R:E182	R:R:M184	5.41	Yes	No	0
149	R:R:H183	R:R:N197	14.03	Yes	No	0
150	R:R:G185	R:R:M184	3.49	No	No	0
151	R:R:H264	R:R:M184	5.25	No	No	0
152	R:R:I194	R:R:K195	2.91	No	No	0
153	R:R:V204	R:R:Y200	8.83	No	Yes	0
154	R:R:L211	R:R:L215	5.54	No	No	0
155	R:R:D212	R:R:I216	7	Yes	No	0
156	R:R:D212	R:R:Y254	6.9	Yes	Yes	0
157	R:R:I216	R:R:I250	4.42	No	No	0
158	R:R:L218	R:R:L222	2.77	No	No	0
159	R:R:C243	R:R:Y220	6.72	No	No	0
160	R:R:H246	R:R:Y220	8.71	Yes	No	0
161	R:R:H246	R:R:I250	6.63	Yes	No	0
162	R:R:H246	R:R:Y294	3.27	Yes	Yes	1
163	R:R:C248	R:R:I293	3.27	No	No	0
164	R:R:N290	R:R:V249	2.96	No	No	0
165	R:R:L251	R:R:T255	4.42	No	No	0
166	R:R:A252	R:R:L289	3.15	No	No	0
167	R:R:F253	R:R:Y254	6.19	No	Yes	0
168	R:R:F253	R:R:P286	2.89	No	No	0
169	R:R:F258	R:R:Y254	5.16	No	Yes	0
170	R:R:P256	R:R:T255	3.5	No	No	0
171	R:R:P256	R:R:Y282	2.78	No	Yes	0
172	R:R:F259	R:R:T263	7.78	No	No	6
173	R:R:F259	R:R:L278	8.53	No	No	6
174	R:R:S260	R:R:Y282	16.53	No	Yes	0
175	R:R:L278	R:R:T263	4.42	No	No	6
176	R:R:F266	R:R:R265	12.83	No	No	0
177	R:R:I270	R:R:P271	3.39	Yes	No	0
178	R:R:I270	R:R:I274	4.42	Yes	No	0
179	R:R:H275	R:R:I270	6.63	No	Yes	0
180	R:R:P271	R:R:Y273	11.13	No	Yes	0
181	R:R:P272	R:R:Y273	4.17	No	Yes	0
182	R:R:L284	R:R:N280	2.75	Yes	Yes	2
183	R:R:L283	R:R:L284	4.15	No	Yes	0
184	R:R:P286	R:R:P287	5.84	No	No	0
185	R:R:I292	R:R:M288	2.92	No	No	0
186	R:R:I292	R:R:L289	5.71	No	No	0
187	R:R:I293	R:R:L289	4.28	No	No	0
188	R:R:V213	R:R:Y254	2.52	No	Yes	0
189	R:R:V249	R:R:Y294	2.52	No	Yes	0
190	R:R:F87	R:R:I19	2.51	Yes	Yes	0
191	R:R:F33	R:R:L281	2.44	Yes	No	0
192	R:R:D97	R:R:F96	2.39	No	No	0
193	R:R:H268	R:R:H269	2.39	No	No	0
194	R:R:L283	R:R:Y282	2.34	No	Yes	0
195	R:R:F14	R:R:F96	2.14	Yes	No	0
196	R:R:R133	R:R:Y130	2.06	No	No	0
197	R:R:F203	R:R:Y200	2.06	No	Yes	0
198	R:R:P177	R:R:P20	1.95	No	No	0
199	R:R:A40	R:R:P287	1.87	No	No	0
200	R:R:G115	R:R:S114	1.86	No	No	0
201	R:R:G115	R:R:V150	1.84	No	No	0
202	R:R:G210	R:R:V209	1.84	No	No	0
203	R:R:G111	R:R:T110	1.82	No	No	0
204	R:R:G267	R:R:T263	1.82	No	No	0
205	R:R:A226	R:R:C129	1.81	No	No	0
206	R:R:P20	R:R:V17	1.77	No	No	0
207	R:R:P286	R:R:V285	1.77	No	No	0
208	R:R:G244	R:R:I247	1.76	No	No	0
209	R:R:C34	R:R:S30	1.72	No	No	0
210	R:R:G43	R:R:L42	1.71	No	No	0
211	R:R:A98	R:R:S95	1.71	No	No	0
212	R:R:S12	R:R:S13	1.63	No	No	0
213	R:R:A66	R:R:I51	1.62	No	No	0
214	R:R:S78	R:R:V74	1.62	No	No	0
215	R:R:A119	R:R:I146	1.62	No	No	0
216	R:R:A154	R:R:M112	1.61	No	Yes	0
217	R:R:T139	R:R:V142	1.59	No	No	0
218	R:R:G267	R:R:H275	1.59	No	No	0
219	R:R:A69	R:R:L48	1.58	No	No	0
220	R:R:A205	R:R:L206	1.58	No	No	0
221	R:R:I51	R:R:V50	1.54	No	No	0
222	R:R:I208	R:R:V209	1.54	No	No	0
223	R:R:K195	R:R:V196	1.52	No	No	0
224	R:R:L41	R:R:S45	1.5	No	No	0
225	R:R:K141	R:R:T139	1.5	No	No	0
226	R:R:L47	R:R:V50	1.49	No	No	0
227	R:R:L42	R:R:T46	1.47	No	No	0
228	R:R:I39	R:R:M288	1.46	No	No	0
229	R:R:E93	R:R:S13	1.44	No	No	0
230	R:R:I176	R:R:L189	1.43	Yes	No	0
231	R:R:I214	R:R:L211	1.43	No	No	0
232	R:R:P131	R:R:Y130	1.39	No	No	0
233	R:R:L156	R:R:L157	1.38	No	No	0
234	R:R:E93	R:R:L91	1.33	No	No	0
235	R:R:A257	R:R:Y282	1.33	No	Yes	0
236	R:R:H269	R:R:I270	1.33	No	Yes	0
237	R:R:S219	R:R:Y125	1.27	No	Yes	0
238	R:R:F259	R:R:L262	1.22	No	No	0
239	R:R:I143	R:R:Y63	1.21	Yes	No	0
240	R:R:L156	R:R:R153	1.21	No	No	0
241	R:R:I199	R:R:Y200	1.21	No	Yes	0
242	R:R:M61	R:R:Y62	1.2	No	No	0
243	R:R:L157	R:R:Y200	1.17	No	Yes	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community
1	R:R:F14	5.8825	4	0
2	R:R:I19	3.89667	6	0
3	R:R:F33	5.488	5	2
4	R:R:N44	7.45	4	0
5	R:R:P60	5.472	5	1
6	R:R:F64	3.826	5	1
7	R:R:T71	4.3125	4	3
8	R:R:M83	11.1525	4	2
9	R:R:F87	7.41	4	2
10	R:R:M103	3.365	4	5
11	R:R:F109	7.26	6	3
12	R:R:M112	3.762	5	3
13	R:R:R124	5.88	4	0
14	R:R:Y125	4.28	4	0
15	R:R:Y134	6.854	5	1
16	R:R:L138	7.1275	4	1
17	R:R:I143	3.3975	4	1
18	R:R:I176	3.575	4	0
19	R:R:H178	6.365	4	2
20	R:R:Y180	7.455	6	2
21	R:R:E182	7.4875	4	2
22	R:R:H183	9.065	4	0
23	R:R:Y200	3.488	5	0
24	R:R:D212	8	4	0
25	R:R:H246	5.622	5	1
26	R:R:Y254	5.1925	4	0
27	R:R:I270	3.9425	4	0
28	R:R:Y273	6.4825	4	0
29	R:R:N280	5.7625	4	2
30	R:R:Y282	5.745	4	0
31	R:R:L284	3.35	4	2
32	R:R:Y294	6.586	5	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:I176	19.1219	3.77	Yes	Yes	0
2	R:R:I176	R:R:L16	18.7591	5.71	Yes	No	0
3	R:R:I176	R:R:P177	41.1466	3.39	Yes	No	0
4	R:R:P177	R:R:P20	43.5656	1.95	No	No	0
5	R:R:I19	R:R:P20	50.6773	3.39	Yes	No	0
6	R:R:I19	R:R:Y273	37.0706	4.84	Yes	Yes	0
7	R:R:F87	R:R:I19	92.1867	2.51	Yes	Yes	0
8	R:R:F87	R:R:S30	13.5825	10.57	Yes	No	0
9	R:R:C34	R:R:S30	10.8612	1.72	No	No	0
10	R:R:F33	R:R:F87	72.9076	5.36	Yes	Yes	2
11	R:R:F87	R:R:M83	29.7291	11.2	Yes	Yes	2
12	R:R:F33	R:R:L284	76.0039	3.65	Yes	Yes	2
13	R:R:I80	R:R:L284	94.1219	2.85	No	Yes	0
14	R:R:I80	R:R:Y37	94.0493	13.3	No	No	0
15	R:R:T77	R:R:Y37	94.1098	9.99	No	No	0
16	R:R:L73	R:R:T77	94.255	2.95	No	No	0
17	R:R:L73	R:R:N44	94.521	12.36	No	Yes	0
18	R:R:D72	R:R:N44	66.3885	9.42	No	Yes	0
19	R:R:D72	R:R:P287	50.9434	9.66	No	No	0
20	R:R:P286	R:R:P287	47.6778	5.84	No	No	0
21	R:R:P286	R:R:V285	23.0648	1.77	No	No	0
22	R:R:M36	R:R:V285	20.5975	4.56	No	No	0
23	R:R:M288	R:R:M36	18.106	2.89	No	No	0
24	R:R:N44	R:R:P291	11.3087	4.89	Yes	No	0
25	R:R:A69	R:R:N44	100	3.13	No	Yes	0
26	R:R:A69	R:R:L47	97.1577	4.73	No	No	0
27	R:R:L47	R:R:L65	92.0295	2.77	No	No	0
28	R:R:L65	R:R:Y294	90.6144	18.76	No	Yes	0
29	R:R:M61	R:R:Y294	21.5167	3.59	No	Yes	0
30	R:R:M120	R:R:Y294	26.1369	4.79	No	Yes	1
31	R:R:F64	R:R:M120	30.5273	3.73	Yes	No	1
32	R:R:F64	R:R:P60	12.0706	2.89	Yes	Yes	1
33	R:R:D123	R:R:Y134	14.2114	3.45	No	Yes	0
34	R:R:D123	R:R:M61	15.3	4.16	No	No	0
35	R:R:L283	R:R:L284	49.492	4.15	No	Yes	0
36	R:R:L283	R:R:Y180	43.8195	8.21	No	Yes	0
37	R:R:I106	R:R:Y180	67.4528	3.63	No	Yes	2
38	R:R:I106	R:R:L75	68.6139	4.28	No	No	0
39	R:R:F109	R:R:L75	68.2511	8.53	Yes	No	0
40	R:R:F109	R:R:T71	55.7329	3.89	Yes	Yes	3
41	R:R:M83	R:R:T179	29.7895	15.05	Yes	No	2
42	R:R:H178	R:R:T179	32.9342	4.11	Yes	No	2
43	R:R:H178	R:R:Y180	18.0092	9.8	Yes	Yes	2
44	R:R:E113	R:R:T71	57.4383	2.82	No	Yes	0
45	R:R:D72	R:R:E113	57.2932	5.2	No	No	0
46	R:R:H183	R:R:M103	14.7557	3.94	Yes	Yes	0
47	R:R:H107	R:R:H183	60.9821	3.58	No	Yes	0
48	R:R:E182	R:R:H107	63.5704	6.15	Yes	No	0
49	R:R:E182	R:R:H178	16.6304	4.92	Yes	Yes	2
50	R:R:F109	R:R:S108	11.7441	2.64	Yes	No	3
51	R:R:F253	R:R:P286	37.6391	2.89	No	No	0
52	R:R:F253	R:R:Y254	36.6231	6.19	No	Yes	0
53	R:R:D212	R:R:Y254	33.7929	6.9	Yes	Yes	0
54	R:R:D212	R:R:S114	19.9202	5.89	Yes	No	0
55	R:R:I208	R:R:S114	12.627	6.19	No	No	0
56	R:R:D212	R:R:L118	10.1476	12.21	Yes	No	0
57	R:R:H246	R:R:Y294	41.7029	3.27	Yes	Yes	1
58	R:R:I223	R:R:Y125	25.0242	6.04	No	Yes	0
59	R:R:I128	R:R:I223	27.5036	11.77	No	No	0
60	R:R:I128	R:R:R124	32.6076	10.02	No	Yes	0
61	R:R:C243	R:R:R124	34.2767	4.18	No	Yes	0
62	R:R:C243	R:R:Y220	36.1877	6.72	No	No	0
63	R:R:H246	R:R:Y220	38.1229	8.71	Yes	No	0
64	R:R:C129	R:R:Y125	16.8965	6.72	No	Yes	0
65	R:R:C129	R:R:Y130	11.357	2.69	No	No	0
66	R:R:F161	R:R:H183	39.7073	14.71	No	Yes	0
67	R:R:F161	R:R:V204	34.3856	2.62	No	No	0
68	R:R:V204	R:R:Y200	31.4344	8.83	No	Yes	0
69	R:R:L157	R:R:Y200	12.8568	1.17	No	Yes	0
70	R:R:H246	R:R:I250	20.1016	6.63	Yes	No	0
71	R:R:I216	R:R:I250	18.5776	4.42	No	No	0
72	R:R:D212	R:R:I216	19.2671	7	Yes	No	0
73	R:R:I292	R:R:L289	10.4862	5.71	No	No	0
74	R:R:I292	R:R:M288	13.0503	2.92	No	No	0
75	R:R:L283	R:R:Y282	16.5094	2.34	No	Yes	0
76	R:R:P271	R:R:Y273	29.5235	11.13	No	Yes	0
77	R:R:I270	R:R:P271	26.9594	3.39	Yes	No	0
78	R:R:H275	R:R:I270	16.4611	6.63	No	Yes	0
79	R:R:G267	R:R:H275	13.7639	1.59	No	No	0
80	R:R:G267	R:R:T263	11.0547	1.82	No	No	0
81	R:R:E182	R:R:Y180	56.628	13.47	Yes	Yes	2

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8J46

PDB Summary
PDB	8J46
Class	O1
SubFamily	Odorant receptors
Type	Odorant family 52
SubType	OR52C
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.66
Date	2023-12-20
D.O.I.	10.1038/s41467-023-43983-9

Net Summary
I_min	2.62
Number of Linked Nodes	233
Number of Links	243
Number of Hubs	32
Number of Links mediated by Hubs	117
Number of Communities	6
Number of Nodes involved in Communities	38
Number of Links involved in Communities	49

Path Summary
Number Of Nodes in MetaPath	82
Number Of Links MetaPath	81
Number of Shortest Paths	23681
Length Of Smallest Path	3
Average Path Length	14.1824
Length of Longest Path	32
Minimum Path Strength	1.19
Average Path Strength	5.85371
Maximum Path Strength	13.375
Minimum Path Correlation	0.7
Average Path Correlation	0.911349
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	41.0929
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.8775
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Cytochromes
SCOP2	Family Identifier	• Cytochromes
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	-
Sequence	>8J46_Chain_R P S S F L L V I P G L E S V H I W I S I P F C A M Y L I A L L G N S T L L F V I K L H E P M Y Y F L A M L A A T D L V L S T S T I P K M L A I F W F N L K E I S F D A C L T Q M F F I H S F T G M E S G V L L A M A F D R Y V A I C Y P L R Y T T I L T N K V I G K I G M A V V L R A V L L V I P F P F L L K R L N I I P H T Y C E H M G V A K L I K V N I I Y G L F V A L L I V G L D V I L I A L S Y V L I L R A L K A L S T C G S H I C V I L A F Y T P A F F S F L T H R F G H H I P P Y I H I L L A N L Y L L V P P M L N P I I Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8W77	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	-	-	-	3.61	2023-12-20	10.1038/s41467-023-43983-9
	8J46	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	-	-	-	3.66	2023-12-20	10.1038/s41467-023-43983-9
	8HTI	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	Ocatnoic acid	-	Gs/β1/γ2	2.97	2023-12-20	10.1038/s41467-023-43983-9
	8HTI (No Gprot)	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	Ocatnoic acid	-		2.97	2023-12-20	10.1038/s41467-023-43983-9

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8J46.zip

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