psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:P11	4.33	Yes	No	0
2	R:R:F14	R:R:I94	2.51	Yes	Yes	0
3	R:R:F14	R:R:F96	2.14	Yes	No	0
4	R:R:F14	R:R:N174	13.29	Yes	No	0
5	R:R:F14	R:R:I176	3.77	Yes	No	0
6	R:R:L15	R:R:N174	2.75	No	No	0
7	R:R:K82	R:R:L16	2.82	No	Yes	3
8	R:R:I86	R:R:L16	2.85	No	Yes	3
9	R:R:I94	R:R:L16	2.85	Yes	Yes	3
10	R:R:I176	R:R:L16	5.71	No	Yes	0
11	R:R:P20	R:R:V17	1.77	Yes	Yes	0
12	R:R:E23	R:R:V17	5.7	No	Yes	3
13	R:R:K92	R:R:V17	6.07	Yes	Yes	3
14	R:R:I19	R:R:P20	3.39	Yes	Yes	0
15	R:R:I19	R:R:L22	4.28	Yes	No	4
16	R:R:I19	R:R:I29	2.94	Yes	No	4
17	R:R:I19	R:R:Y273	3.63	Yes	No	4
18	R:R:G21	R:R:P20	2.03	No	Yes	0
19	R:R:P177	R:R:P20	1.95	No	Yes	0
20	R:R:I29	R:R:L22	4.28	No	No	4
21	R:R:E23	R:R:K92	2.7	No	Yes	3
22	R:R:H26	R:R:I27	2.65	No	No	0
23	R:R:F87	R:R:S30	10.57	Yes	No	2
24	R:R:S30	R:R:W88	4.94	No	Yes	2
25	R:R:I31	R:R:P32	8.47	No	No	0
26	R:R:F33	R:R:M83	9.95	Yes	Yes	2
27	R:R:F33	R:R:F87	5.36	Yes	Yes	2
28	R:R:F33	R:R:N280	6.04	Yes	Yes	2
29	R:R:F33	R:R:L284	3.65	Yes	Yes	2
30	R:R:A35	R:R:C34	1.81	No	No	0
31	R:R:M36	R:R:V285	6.09	No	No	0
32	R:R:M288	R:R:M36	4.33	No	No	0
33	R:R:L41	R:R:Y37	2.34	No	No	0
34	R:R:T77	R:R:Y37	9.99	No	No	0
35	R:R:I80	R:R:Y37	13.3	Yes	No	0
36	R:R:I39	R:R:M288	8.75	No	No	0
37	R:R:A40	R:R:P287	1.87	No	Yes	0
38	R:R:L41	R:R:L73	2.77	No	No	0
39	R:R:G43	R:R:T46	1.82	No	No	0
40	R:R:G43	R:R:P291	4.06	No	No	0
41	R:R:A69	R:R:N44	3.13	No	Yes	0
42	R:R:D72	R:R:N44	9.42	Yes	Yes	0
43	R:R:L73	R:R:N44	15.1	No	Yes	0
44	R:R:N44	R:R:P291	4.89	Yes	No	0
45	R:R:L47	R:R:T46	2.95	No	No	0
46	R:R:A69	R:R:L47	3.15	No	No	0
47	R:R:L47	R:R:P291	6.57	No	No	0
48	R:R:F49	R:R:K52	4.96	No	No	0
49	R:R:L57	R:R:Y62	11.72	No	No	0
50	R:R:H58	R:R:Y63	4.36	No	No	0
51	R:R:E59	R:R:P60	4.72	No	Yes	0
52	R:R:F64	R:R:P60	2.89	Yes	Yes	1
53	R:R:P60	R:R:Y134	9.74	Yes	Yes	0
54	R:R:L138	R:R:P60	11.49	No	Yes	1
55	R:R:M61	R:R:Y62	3.59	Yes	No	0
56	R:R:L65	R:R:M61	8.48	No	Yes	1
57	R:R:D123	R:R:M61	4.16	No	Yes	0
58	R:R:M61	R:R:R124	3.72	Yes	Yes	0
59	R:R:M61	R:R:Y294	4.79	Yes	Yes	1
60	R:R:I143	R:R:Y63	4.84	Yes	No	0
61	R:R:A119	R:R:F64	2.77	No	Yes	0
62	R:R:F64	R:R:M120	3.73	Yes	Yes	1
63	R:R:D123	R:R:F64	4.78	No	Yes	0
64	R:R:F64	R:R:L138	2.44	Yes	No	1
65	R:R:F64	R:R:I143	5.02	Yes	Yes	1
66	R:R:L65	R:R:M120	4.24	No	Yes	1
67	R:R:L65	R:R:Y294	16.41	No	Yes	1
68	R:R:M67	R:R:V116	4.56	No	Yes	0
69	R:R:F109	R:R:T71	3.89	Yes	No	5
70	R:R:M112	R:R:T71	15.05	Yes	No	5
71	R:R:E113	R:R:T71	4.23	No	No	0
72	R:R:D72	R:R:S76	4.42	Yes	No	7
73	R:R:D72	R:R:E113	2.6	Yes	No	0
74	R:R:D72	R:R:P287	9.66	Yes	Yes	7
75	R:R:F109	R:R:V74	7.87	Yes	No	0
76	R:R:I106	R:R:L75	4.28	No	No	0
77	R:R:F109	R:R:L75	8.53	Yes	No	0
78	R:R:E113	R:R:L75	6.63	No	No	0
79	R:R:P287	R:R:S76	5.34	Yes	No	7
80	R:R:F105	R:R:S78	2.64	Yes	No	0
81	R:R:I80	R:R:T79	3.04	Yes	No	0
82	R:R:I106	R:R:T79	4.56	No	No	0
83	R:R:I80	R:R:P81	3.39	Yes	No	0
84	R:R:I80	R:R:L84	4.28	Yes	No	0
85	R:R:I80	R:R:L284	4.28	Yes	Yes	0
86	R:R:I86	R:R:K82	2.91	No	No	3
87	R:R:I94	R:R:K82	2.91	Yes	No	3
88	R:R:F87	R:R:M83	11.2	Yes	Yes	2
89	R:R:M83	R:R:T179	15.05	Yes	Yes	2
90	R:R:M83	R:R:N280	8.41	Yes	Yes	2
91	R:R:L84	R:R:W88	11.39	No	Yes	0
92	R:R:I86	R:R:K92	5.82	No	Yes	3
93	R:R:F87	R:R:W88	2	Yes	Yes	2
94	R:R:F87	R:R:T179	2.59	Yes	Yes	2
95	R:R:F89	R:R:W88	3.01	No	Yes	0
96	R:R:F89	R:R:L91	4.87	No	No	0
97	R:R:K92	R:R:N90	5.6	Yes	No	0
98	R:R:A98	R:R:I94	3.25	No	Yes	0
99	R:R:D97	R:R:F96	2.39	No	No	0
100	R:R:F96	R:R:L100	9.74	No	No	0
101	R:R:C181	R:R:C99	7.28	No	No	3
102	R:R:F105	R:R:T101	2.59	Yes	No	0
103	R:R:H107	R:R:M103	2.63	No	No	6
104	R:R:M103	R:R:P162	3.35	No	No	0
105	R:R:H183	R:R:M103	2.63	Yes	No	6
106	R:R:F104	R:R:F105	4.29	Yes	Yes	0
107	R:R:F104	R:R:S108	2.64	Yes	No	5
108	R:R:F104	R:R:V158	6.55	Yes	No	5
109	R:R:F104	R:R:I159	2.51	Yes	No	0
110	R:R:F104	R:R:P162	5.78	Yes	No	0
111	R:R:F105	R:R:F109	2.14	Yes	Yes	0
112	R:R:I106	R:R:Y180	3.63	No	Yes	0
113	R:R:H107	R:R:H183	3.58	No	Yes	6
114	R:R:F109	R:R:S108	3.96	Yes	No	5
115	R:R:S108	R:R:V158	4.85	No	No	5
116	R:R:F109	R:R:M112	2.49	Yes	Yes	5
117	R:R:G111	R:R:T110	1.82	No	No	0
118	R:R:G111	R:R:I208	3.53	No	Yes	0
119	R:R:G115	R:R:S114	1.86	No	No	0
120	R:R:D212	R:R:S114	5.89	Yes	No	0
121	R:R:G115	R:R:V150	1.84	No	No	8
122	R:R:G115	R:R:R153	4.5	No	No	8
123	R:R:L117	R:R:V249	2.98	No	Yes	0
124	R:R:F253	R:R:L117	2.44	No	No	0
125	R:R:D212	R:R:L118	8.14	Yes	No	0
126	R:R:L118	R:R:L215	8.3	No	No	0
127	R:R:H246	R:R:M120	3.94	Yes	Yes	1
128	R:R:M120	R:R:Y294	3.59	Yes	Yes	1
129	R:R:A121	R:R:H246	2.93	No	Yes	0
130	R:R:F122	R:R:Y125	3.09	No	No	0
131	R:R:D123	R:R:Y134	4.6	No	Yes	0
132	R:R:R124	R:R:T242	3.88	Yes	No	0
133	R:R:C243	R:R:R124	6.96	No	Yes	0
134	R:R:C129	R:R:Y125	6.72	No	No	0
135	R:R:V126	R:R:Y134	2.52	No	Yes	0
136	R:R:A127	R:R:Y134	2.67	No	Yes	0
137	R:R:I128	R:R:I223	10.3	No	No	0
138	R:R:C129	R:R:Y130	2.69	No	No	0
139	R:R:A226	R:R:C129	1.81	No	No	0
140	R:R:I137	R:R:R133	2.51	No	No	0
141	R:R:I143	R:R:L138	4.28	Yes	No	1
142	R:R:N140	R:R:T139	4.39	No	No	0
143	R:R:G144	R:R:I143	3.53	No	Yes	0
144	R:R:K145	R:R:M148	7.2	No	No	0
145	R:R:G147	R:R:I146	3.53	No	No	0
146	R:R:G147	R:R:V150	1.84	No	No	0
147	R:R:A149	R:R:L152	3.15	No	No	0
148	R:R:R153	R:R:V150	11.77	No	No	8
149	R:R:I159	R:R:P160	6.77	No	No	0
150	R:R:F161	R:R:H183	14.71	No	Yes	0
151	R:R:F161	R:R:G201	3.01	No	No	0
152	R:R:F161	R:R:V204	2.62	No	No	0
153	R:R:L164	R:R:N197	12.36	No	No	6
154	R:R:L164	R:R:Y200	2.34	No	Yes	6
155	R:R:L165	R:R:V186	2.98	No	No	0
156	R:R:L168	R:R:R167	2.43	No	No	0
157	R:R:I176	R:R:P177	3.39	No	No	0
158	R:R:H178	R:R:T179	4.11	Yes	Yes	2
159	R:R:H178	R:R:Y180	9.8	Yes	Yes	2
160	R:R:E182	R:R:H178	9.85	No	Yes	2
161	R:R:H178	R:R:I276	6.63	Yes	No	0
162	R:R:N280	R:R:T179	5.85	Yes	Yes	2
163	R:R:E182	R:R:Y180	13.47	No	Yes	2
164	R:R:N280	R:R:Y180	2.33	Yes	Yes	2
165	R:R:L283	R:R:Y180	8.21	No	Yes	0
166	R:R:E182	R:R:M184	2.71	No	No	0
167	R:R:H183	R:R:N197	11.48	Yes	No	6
168	R:R:I194	R:R:K195	2.91	No	No	0
169	R:R:V196	R:R:Y200	6.31	No	Yes	0
170	R:R:N197	R:R:Y200	3.49	No	Yes	6
171	R:R:I199	R:R:Y200	7.25	No	Yes	0
172	R:R:F203	R:R:I199	12.56	No	No	0
173	R:R:I208	R:R:V209	3.07	Yes	No	0
174	R:R:G210	R:R:V209	1.84	No	No	0
175	R:R:L211	R:R:L215	5.54	No	No	0
176	R:R:D212	R:R:I216	9.8	Yes	Yes	1
177	R:R:D212	R:R:Y254	8.05	Yes	Yes	1
178	R:R:V213	R:R:Y254	2.52	No	Yes	0
179	R:R:I216	R:R:Y220	2.42	Yes	Yes	0
180	R:R:I216	R:R:I250	4.42	Yes	No	1
181	R:R:I216	R:R:Y254	2.42	Yes	Yes	1
182	R:R:C243	R:R:Y220	6.72	No	Yes	0
183	R:R:H246	R:R:Y220	8.71	Yes	Yes	0
184	R:R:I247	R:R:Y220	9.67	No	Yes	0
185	R:R:I223	R:R:L240	2.85	No	No	0
186	R:R:L237	R:R:S241	3	No	No	0
187	R:R:H246	R:R:I250	6.63	Yes	No	1
188	R:R:H246	R:R:Y294	3.27	Yes	Yes	1
189	R:R:C248	R:R:I293	3.27	No	Yes	0
190	R:R:N290	R:R:V249	2.96	No	Yes	0
191	R:R:V249	R:R:Y294	2.52	Yes	Yes	0
192	R:R:I250	R:R:Y254	2.42	No	Yes	1
193	R:R:L251	R:R:T255	2.95	No	No	0
194	R:R:F253	R:R:Y254	6.19	No	Yes	0
195	R:R:F253	R:R:P286	2.89	No	No	0
196	R:R:P256	R:R:T255	5.25	No	No	0
197	R:R:P256	R:R:Y282	6.95	No	No	0
198	R:R:A257	R:R:Y282	4	No	No	0
199	R:R:L278	R:R:S260	3	No	No	0
200	R:R:S260	R:R:Y282	13.99	No	No	0
201	R:R:L278	R:R:T263	5.9	No	No	0
202	R:R:F266	R:R:R265	6.41	No	No	0
203	R:R:I270	R:R:P271	3.39	Yes	Yes	4
204	R:R:I270	R:R:I274	8.83	Yes	Yes	4
205	R:R:H275	R:R:I270	10.61	No	Yes	4
206	R:R:P271	R:R:P272	1.95	Yes	No	0
207	R:R:P271	R:R:Y273	5.56	Yes	No	4
208	R:R:I274	R:R:P271	5.08	Yes	Yes	4
209	R:R:I274	R:R:Y273	4.84	Yes	No	4
210	R:R:H275	R:R:I274	5.3	No	Yes	4
211	R:R:L284	R:R:N280	2.75	Yes	Yes	2
212	R:R:L281	R:R:V285	7.45	No	No	0
213	R:R:L283	R:R:L284	4.15	No	Yes	0
214	R:R:P286	R:R:V285	1.77	No	No	0
215	R:R:P286	R:R:P287	5.84	No	Yes	0
216	R:R:I293	R:R:L289	5.71	Yes	No	0
217	R:R:G267	R:R:I270	1.76	No	Yes	0
218	R:R:G185	R:R:M184	1.75	No	No	0
219	R:R:G43	R:R:L42	1.71	No	No	0
220	R:R:A98	R:R:S95	1.71	No	No	0
221	R:R:C99	R:R:V186	1.71	No	No	3
222	R:R:C181	R:R:V186	1.71	No	No	3
223	R:R:I276	R:R:P20	1.69	No	Yes	0
224	R:R:C99	R:R:I94	1.64	No	Yes	3
225	R:R:C181	R:R:I94	1.64	No	Yes	3
226	R:R:S12	R:R:S13	1.63	No	No	0
227	R:R:S24	R:R:V25	1.62	No	No	0
228	R:R:A66	R:R:I51	1.62	No	No	0
229	R:R:A239	R:R:I128	1.62	No	No	0
230	R:R:A154	R:R:I208	1.62	No	Yes	0
231	R:R:V151	R:R:V155	1.6	No	No	0
232	R:R:C34	R:R:L84	1.59	No	No	0
233	R:R:T139	R:R:V142	1.59	No	No	0
234	R:R:A69	R:R:L48	1.58	No	No	0
235	R:R:A205	R:R:L206	1.58	No	No	0
236	R:R:A252	R:R:L289	1.58	No	No	0
237	R:R:T135	R:R:T136	1.57	No	No	0
238	R:R:I208	R:R:S114	1.55	Yes	No	0
239	R:R:I175	R:R:V17	1.54	No	Yes	0
240	R:R:I51	R:R:V50	1.54	No	No	0
241	R:R:I137	R:R:V126	1.54	No	No	0
242	R:R:I146	R:R:V142	1.54	No	No	0
243	R:R:I293	R:R:V249	1.54	Yes	Yes	0
244	R:R:M112	R:R:V116	1.52	Yes	Yes	0
245	R:R:M112	R:R:V151	1.52	Yes	No	0
246	R:R:M120	R:R:V116	1.52	Yes	Yes	0
247	R:R:K195	R:R:V196	1.52	No	No	0
248	R:R:L41	R:R:S45	1.5	No	No	0
249	R:R:L42	R:R:S45	1.5	No	No	0
250	R:R:K141	R:R:T139	1.5	No	No	0
251	R:R:L22	R:R:V25	1.49	No	No	0
252	R:R:L68	R:R:V116	1.49	No	Yes	0
253	R:R:I292	R:R:I293	1.47	No	Yes	0
254	R:R:E93	R:R:S13	1.44	No	No	0
255	R:R:Q102	R:R:S78	1.44	No	No	0
256	R:R:K141	R:R:K145	1.44	No	No	0
257	R:R:I223	R:R:L224	1.43	No	No	0
258	R:R:I274	R:R:L278	1.43	Yes	No	0
259	R:R:L152	R:R:M148	1.41	No	No	0
260	R:R:P131	R:R:Y130	1.39	No	No	0
261	R:R:L152	R:R:L156	1.38	No	No	0
262	R:R:E93	R:R:L15	1.33	No	No	0
263	R:R:E93	R:R:L91	1.33	No	No	0
264	R:R:S219	R:R:Y125	1.27	No	No	0
265	R:R:I128	R:R:R124	1.25	No	Yes	0
266	R:R:T135	R:R:Y134	1.25	No	Yes	0
267	R:R:V25	R:R:W28	1.23	No	No	0
268	R:R:F14	R:R:L189	1.22	Yes	No	0
269	R:R:F33	R:R:L277	1.22	Yes	No	0
270	R:R:I31	R:R:W28	1.17	No	No	0
271	R:R:R133	R:R:Y130	1.03	No	No	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community
1	R:R:F14	4.54333	6	0
2	R:R:L16	3.5575	4	3
3	R:R:V17	3.77	4	3
4	R:R:I19	3.56	4	4
5	R:R:P20	2.166	5	0
6	R:R:F33	5.244	5	2
7	R:R:N44	8.135	4	0
8	R:R:P60	7.21	4	1
9	R:R:M61	4.948	5	1
10	R:R:F64	3.605	6	1
11	R:R:D72	6.525	4	7
12	R:R:I80	5.658	5	0
13	R:R:M83	11.1525	4	2
14	R:R:F87	6.344	5	2
15	R:R:W88	5.335	4	2
16	R:R:K92	5.0475	4	3
17	R:R:I94	2.46667	6	3
18	R:R:F104	4.354	5	5
19	R:R:F105	2.915	4	0
20	R:R:F109	4.81333	6	5
21	R:R:M112	5.145	4	5
22	R:R:V116	2.2725	4	0
23	R:R:M120	3.404	5	1
24	R:R:R124	3.9525	4	0
25	R:R:Y134	4.156	5	0
26	R:R:I143	4.4175	4	1
27	R:R:H178	7.5975	4	2
28	R:R:T179	6.9	4	2
29	R:R:Y180	7.488	5	2
30	R:R:H183	8.1	4	6
31	R:R:Y200	4.8475	4	6
32	R:R:I208	2.4425	4	0
33	R:R:D212	7.97	4	1
34	R:R:I216	4.765	4	1
35	R:R:Y220	6.88	4	0
36	R:R:H246	5.096	5	1
37	R:R:V249	2.5	4	0
38	R:R:Y254	4.32	5	1
39	R:R:I270	6.1475	4	4
40	R:R:P271	3.995	4	4
41	R:R:I274	5.096	5	4
42	R:R:N280	5.076	5	2
43	R:R:L284	3.7075	4	2
44	R:R:P287	5.6775	4	7
45	R:R:I293	2.9975	4	0
46	R:R:Y294	6.116	5	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:I94	13.2227	2.51	Yes	Yes	0
2	R:R:I94	R:R:L16	11.6475	2.85	Yes	Yes	3
3	R:R:F14	R:R:I176	21.3132	3.77	Yes	No	0
4	R:R:I176	R:R:L16	14.1599	5.71	No	Yes	0
5	R:R:I176	R:R:P177	36.0716	3.39	No	No	0
6	R:R:P177	R:R:P20	37.4323	1.95	No	Yes	0
7	R:R:P20	R:R:V17	10.9361	1.77	Yes	Yes	0
8	R:R:I19	R:R:P20	39.7527	3.39	Yes	Yes	0
9	R:R:I19	R:R:L22	10.3602	4.28	Yes	No	4
10	R:R:I19	R:R:Y273	27.7947	3.63	Yes	No	4
11	R:R:F89	R:R:W88	10.682	3.01	No	Yes	0
12	R:R:I276	R:R:P20	78.4214	1.69	No	Yes	0
13	R:R:H178	R:R:I276	79.1893	6.63	Yes	No	0
14	R:R:H178	R:R:T179	10.0045	4.11	Yes	Yes	2
15	R:R:H178	R:R:Y180	75.0508	9.8	Yes	Yes	2
16	R:R:N280	R:R:Y180	14.4591	2.33	Yes	Yes	2
17	R:R:L84	R:R:W88	12.6242	11.39	No	Yes	0
18	R:R:I106	R:R:Y180	85.682	3.63	No	Yes	0
19	R:R:I106	R:R:L75	100	4.28	No	No	0
20	R:R:E113	R:R:L75	35.0836	6.63	No	No	0
21	R:R:D72	R:R:E113	47.0359	2.6	Yes	No	0
22	R:R:D72	R:R:P287	36.5628	9.66	Yes	Yes	7
23	R:R:P286	R:R:P287	35.4844	5.84	No	Yes	0
24	R:R:I80	R:R:L84	15.3286	4.28	Yes	No	0
25	R:R:I80	R:R:Y37	13.5445	13.3	Yes	No	0
26	R:R:L41	R:R:Y37	10.507	2.34	No	No	0
27	R:R:D72	R:R:N44	26.3437	9.42	Yes	Yes	0
28	R:R:N44	R:R:P291	10.2473	4.89	Yes	No	0
29	R:R:F109	R:R:L75	78.2633	8.53	Yes	No	0
30	R:R:F109	R:R:M112	84.2536	2.49	Yes	Yes	5
31	R:R:M112	R:R:V116	91.8248	1.52	Yes	Yes	0
32	R:R:M120	R:R:V116	91.5086	1.52	Yes	Yes	0
33	R:R:L65	R:R:M120	10.0158	4.24	No	Yes	1
34	R:R:M120	R:R:Y294	17.1522	3.59	Yes	Yes	1
35	R:R:M61	R:R:Y294	20.8616	4.79	Yes	Yes	1
36	R:R:F64	R:R:M120	55.6798	3.73	Yes	Yes	1
37	R:R:F64	R:R:P60	23.8708	2.89	Yes	Yes	1
38	R:R:P60	R:R:Y134	21.3189	9.74	Yes	Yes	0
39	R:R:D123	R:R:F64	22.561	4.78	No	Yes	0
40	R:R:D123	R:R:Y134	32.3735	4.6	No	Yes	0
41	R:R:M61	R:R:R124	17.4232	3.72	Yes	Yes	0
42	R:R:E113	R:R:T71	14.318	4.23	No	No	0
43	R:R:F105	R:R:F109	39.2559	2.14	Yes	Yes	0
44	R:R:I106	R:R:T79	18.6822	4.56	No	No	0
45	R:R:F104	R:R:F105	32.4131	4.29	Yes	Yes	0
46	R:R:F104	R:R:P162	54.0029	5.78	Yes	No	0
47	R:R:M103	R:R:P162	50.9316	3.35	No	No	0
48	R:R:F109	R:R:S108	35.8458	3.96	Yes	No	5
49	R:R:F104	R:R:S108	32.3114	2.64	Yes	No	5
50	R:R:H183	R:R:M103	43.6032	2.63	Yes	No	6
51	R:R:F253	R:R:P286	31.0806	2.89	No	No	0
52	R:R:F253	R:R:Y254	26.6034	6.19	No	Yes	0
53	R:R:D212	R:R:Y254	38.0081	8.05	Yes	Yes	1
54	R:R:D212	R:R:S114	62.8331	5.89	Yes	No	0
55	R:R:I208	R:R:S114	18.4564	1.55	Yes	No	0
56	R:R:G115	R:R:S114	42.4402	1.86	No	No	0
57	R:R:G115	R:R:V150	36.4442	1.84	No	No	8
58	R:R:V249	R:R:Y294	11.495	2.52	Yes	Yes	0
59	R:R:H246	R:R:M120	48.086	3.94	Yes	Yes	1
60	R:R:C129	R:R:Y125	11.6813	6.72	No	No	0
61	R:R:C129	R:R:Y130	19.4162	2.69	No	No	0
62	R:R:R133	R:R:Y130	27.1059	1.03	No	No	0
63	R:R:I137	R:R:R133	30.9338	2.51	No	No	0
64	R:R:I137	R:R:V126	34.7505	1.54	No	No	0
65	R:R:V126	R:R:Y134	38.5558	2.52	No	Yes	0
66	R:R:H246	R:R:Y220	20.4325	8.71	Yes	Yes	0
67	R:R:I128	R:R:R124	12.2121	1.25	No	Yes	0
68	R:R:G147	R:R:V150	33.5309	1.84	No	No	0
69	R:R:G147	R:R:I146	30.5386	3.53	No	No	0
70	R:R:I146	R:R:V142	27.535	1.54	No	No	0
71	R:R:T139	R:R:V142	24.5201	1.59	No	No	0
72	R:R:K141	R:R:T139	18.4564	1.5	No	No	0
73	R:R:K141	R:R:K145	15.4076	1.44	No	No	0
74	R:R:K145	R:R:M148	12.3476	7.2	No	No	0
75	R:R:F161	R:R:H183	10.9925	14.71	No	Yes	0
76	R:R:H183	R:R:N197	29.7821	11.48	Yes	No	6
77	R:R:N197	R:R:Y200	22.386	3.49	No	Yes	6
78	R:R:V196	R:R:Y200	11.2579	6.31	No	Yes	0
79	R:R:I216	R:R:Y220	22.911	2.42	Yes	Yes	0
80	R:R:H246	R:R:I250	36.2918	6.63	Yes	No	1
81	R:R:I216	R:R:I250	17.1522	4.42	Yes	No	1
82	R:R:I274	R:R:Y273	19.5065	4.84	Yes	No	4
83	R:R:I274	R:R:L278	13.0702	1.43	Yes	No	0
84	R:R:L278	R:R:S260	10.0158	3	No	No	0
85	R:R:I80	R:R:T79	17.4853	3.04	Yes	No	0
86	R:R:I250	R:R:Y254	18.2757	2.42	No	Yes	1
87	R:R:D123	R:R:M61	12.5847	4.16	No	Yes	0
88	R:R:D212	R:R:I216	36.1281	9.8	Yes	Yes	1

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8W77

PDB Summary
PDB	8W77
Class	O1
SubFamily	Odorant receptors
Type	Odorant family 52
SubType	OR52C
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.61
Date	2023-12-20
D.O.I.	10.1038/s41467-023-43983-9

Net Summary
I_min	1.77
Number of Linked Nodes	231
Number of Links	271
Number of Hubs	46
Number of Links mediated by Hubs	160
Number of Communities	8
Number of Nodes involved in Communities	60
Number of Links involved in Communities	82

Path Summary
Number Of Nodes in MetaPath	89
Number Of Links MetaPath	88
Number of Shortest Paths	46580
Length Of Smallest Path	3
Average Path Length	13.8654
Length of Longest Path	34
Minimum Path Strength	1.2
Average Path Strength	4.41318
Maximum Path Strength	12.85
Minimum Path Correlation	0.7
Average Path Correlation	0.914606
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	39.5066
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.3394
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	-
Sequence	>8W77_Chain_R P S S F L L V I P G L E S V H I W I S I P F C A M Y L I A L L G N S T L L F V I K L H E P M Y Y F L A M L A A T D L V L S T S T I P K M L A I F W F N L K E I S F D A C L T Q M F F I H S F T G M E S G V L L A M A F D R Y V A I C Y P L R Y T T I L T N K V I G K I G M A V V L R A V L L V I P F P F L L K R L N I I P H T Y C E H M G V A K L I K V N I I Y G L F V A L L I V G L D V I L I A L S Y V L I L R A L K A L S T C G S H I C V I L A F Y T P A F F S F L T H R F G H H I P P Y I H I L L A N L Y L L V P P M L N P I I Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8W77	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	-	-	-	3.61	2023-12-20	10.1038/s41467-023-43983-9
	8J46	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	-	-	-	3.66	2023-12-20	10.1038/s41467-023-43983-9
	8HTI	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	Ocatnoic acid	-	Gs/β1/γ2	2.97	2023-12-20	10.1038/s41467-023-43983-9
	8HTI (No Gprot)	O1	Odorant receptors	Odorant family 52	OR52C	Homo sapiens	Ocatnoic acid	-		2.97	2023-12-20	10.1038/s41467-023-43983-9

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8W77.zip

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