psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:P11	4.33	No	No	0
2	R:R:F14	R:R:I176	3.77	No	Yes	0
3	R:R:L15	R:R:N174	5.49	No	No	0
4	R:R:K82	R:R:L16	2.82	No	Yes	4
5	R:R:I86	R:R:L16	4.28	No	Yes	0
6	R:R:I94	R:R:L16	2.85	No	Yes	4
7	R:R:I176	R:R:L16	5.71	Yes	Yes	0
8	R:R:I175	R:R:V17	3.07	No	No	0
9	R:R:I19	R:R:P20	3.39	Yes	Yes	0
10	R:R:I19	R:R:L22	4.28	Yes	No	0
11	R:R:I19	R:R:I29	2.94	Yes	No	0
12	R:R:I19	R:R:L277	5.71	Yes	No	0
13	R:R:L22	R:R:Y273	3.52	No	No	0
14	R:R:S24	R:R:V25	3.23	No	No	0
15	R:R:V25	R:R:W28	6.13	No	No	0
16	R:R:H26	R:R:I27	7.95	No	No	0
17	R:R:H26	R:R:N90	7.65	No	No	0
18	R:R:F87	R:R:S30	3.96	No	No	0
19	R:R:I31	R:R:P32	3.39	No	No	0
20	R:R:C34	R:R:I31	3.27	No	No	0
21	R:R:F33	R:R:M83	3.73	Yes	No	2
22	R:R:F33	R:R:F87	5.36	Yes	No	0
23	R:R:F33	R:R:N280	6.04	Yes	Yes	2
24	R:R:F33	R:R:L284	2.44	Yes	Yes	2
25	R:R:M36	R:R:V285	3.04	No	Yes	0
26	R:R:M288	R:R:M36	4.33	No	No	0
27	R:R:T77	R:R:Y37	6.24	No	No	0
28	R:R:I80	R:R:Y37	13.3	Yes	No	0
29	R:R:L41	R:R:L73	6.92	No	Yes	0
30	R:R:G43	R:R:P291	4.06	No	No	0
31	R:R:A69	R:R:N44	3.13	No	Yes	0
32	R:R:D72	R:R:N44	9.42	No	Yes	0
33	R:R:L73	R:R:N44	12.36	Yes	Yes	0
34	R:R:N44	R:R:P291	4.89	Yes	No	0
35	R:R:L47	R:R:P291	4.93	No	No	0
36	R:R:K52	R:R:L48	4.23	No	No	0
37	R:R:L57	R:R:Y62	9.38	No	No	0
38	R:R:F64	R:R:P60	2.89	Yes	Yes	1
39	R:R:D123	R:R:P60	6.44	Yes	Yes	1
40	R:R:P60	R:R:Y134	9.74	Yes	Yes	1
41	R:R:L138	R:R:P60	4.93	Yes	Yes	1
42	R:R:I143	R:R:P60	3.39	Yes	Yes	1
43	R:R:D123	R:R:M61	9.7	Yes	No	0
44	R:R:M61	R:R:R124	8.69	No	Yes	0
45	R:R:M67	R:R:Y63	16.76	No	No	0
46	R:R:I143	R:R:Y63	2.42	Yes	No	0
47	R:R:A119	R:R:F64	2.77	No	Yes	0
48	R:R:F64	R:R:M120	4.98	Yes	Yes	1
49	R:R:D123	R:R:F64	7.17	Yes	Yes	1
50	R:R:F64	R:R:I143	3.77	Yes	Yes	1
51	R:R:L65	R:R:M120	4.24	No	Yes	1
52	R:R:L65	R:R:Y294	16.41	No	Yes	1
53	R:R:E113	R:R:L68	3.98	No	No	0
54	R:R:F109	R:R:T71	3.89	Yes	No	5
55	R:R:M112	R:R:T71	3.01	Yes	No	5
56	R:R:D72	R:R:P287	9.66	No	No	0
57	R:R:L73	R:R:S76	3	Yes	No	0
58	R:R:L73	R:R:T77	2.95	Yes	No	0
59	R:R:F109	R:R:V74	7.87	Yes	No	0
60	R:R:I106	R:R:L75	4.28	Yes	No	0
61	R:R:F109	R:R:L75	8.53	Yes	No	0
62	R:R:S78	R:R:T79	3.2	No	Yes	0
63	R:R:I80	R:R:T79	3.04	Yes	Yes	0
64	R:R:Q102	R:R:T79	2.83	Yes	Yes	2
65	R:R:I106	R:R:T79	4.56	Yes	Yes	2
66	R:R:I80	R:R:P81	3.39	Yes	No	0
67	R:R:I80	R:R:L84	2.85	Yes	No	0
68	R:R:I80	R:R:L284	5.71	Yes	Yes	0
69	R:R:I94	R:R:K82	4.36	No	No	4
70	R:R:M83	R:R:T179	15.05	No	Yes	2
71	R:R:M83	R:R:N280	9.82	No	Yes	2
72	R:R:I86	R:R:K92	11.63	No	No	0
73	R:R:F87	R:R:T179	2.59	No	Yes	0
74	R:R:F89	R:R:W88	37.08	No	No	0
75	R:R:E93	R:R:L91	18.55	No	No	0
76	R:R:A98	R:R:I94	3.25	No	No	0
77	R:R:A98	R:R:S95	3.42	No	No	0
78	R:R:F96	R:R:L100	9.74	Yes	No	0
79	R:R:F96	R:R:K166	4.96	Yes	No	0
80	R:R:C99	R:R:M103	3.24	No	Yes	2
81	R:R:C181	R:R:C99	7.28	Yes	No	2
82	R:R:F105	R:R:T101	2.59	No	No	0
83	R:R:I106	R:R:Q102	5.49	Yes	Yes	2
84	R:R:Q102	R:R:Y180	3.38	Yes	Yes	2
85	R:R:C181	R:R:Q102	3.05	Yes	Yes	2
86	R:R:C181	R:R:M103	3.24	Yes	Yes	2
87	R:R:H183	R:R:M103	3.94	Yes	Yes	0
88	R:R:M103	R:R:V186	3.04	Yes	No	2
89	R:R:F104	R:R:V158	6.55	No	No	0
90	R:R:F104	R:R:I159	3.77	No	Yes	0
91	R:R:F104	R:R:P162	5.78	No	No	0
92	R:R:F105	R:R:F109	4.29	No	Yes	0
93	R:R:I106	R:R:Y180	3.63	Yes	Yes	2
94	R:R:E182	R:R:H107	7.39	No	No	0
95	R:R:H107	R:R:H183	3.58	No	Yes	0
96	R:R:F109	R:R:S108	5.28	Yes	No	0
97	R:R:S108	R:R:V158	4.85	No	No	0
98	R:R:F109	R:R:M112	2.49	Yes	Yes	5
99	R:R:G111	R:R:T110	3.64	No	No	0
100	R:R:M112	R:R:V151	7.61	Yes	No	0
101	R:R:A154	R:R:M112	3.22	No	Yes	0
102	R:R:E113	R:R:F253	13.99	No	Yes	0
103	R:R:D212	R:R:S114	8.83	No	No	0
104	R:R:M120	R:R:V116	3.04	Yes	No	0
105	R:R:L117	R:R:V249	2.98	No	Yes	0
106	R:R:F253	R:R:L117	2.44	Yes	No	0
107	R:R:D212	R:R:L118	5.43	No	No	0
108	R:R:L118	R:R:L215	6.92	No	No	0
109	R:R:H246	R:R:M120	3.94	Yes	Yes	1
110	R:R:M120	R:R:Y294	3.59	Yes	Yes	1
111	R:R:A121	R:R:H246	2.93	No	Yes	0
112	R:R:F122	R:R:Y125	3.09	No	Yes	0
113	R:R:D123	R:R:Y134	10.34	Yes	Yes	1
114	R:R:D123	R:R:L138	5.43	Yes	Yes	1
115	R:R:C243	R:R:R124	2.79	No	Yes	0
116	R:R:R124	R:R:S245	2.64	Yes	No	1
117	R:R:H246	R:R:R124	14.67	Yes	Yes	1
118	R:R:R124	R:R:Y294	5.14	Yes	Yes	1
119	R:R:C129	R:R:Y125	6.72	No	Yes	0
120	R:R:I223	R:R:Y125	3.63	No	Yes	0
121	R:R:V126	R:R:Y134	2.52	No	Yes	1
122	R:R:I137	R:R:V126	3.07	No	No	0
123	R:R:L138	R:R:V126	2.98	Yes	No	1
124	R:R:A127	R:R:Y134	2.67	No	Yes	0
125	R:R:I128	R:R:I223	10.3	No	No	0
126	R:R:C129	R:R:Y130	2.69	No	No	0
127	R:R:R133	R:R:T136	19.41	No	No	0
128	R:R:I137	R:R:R133	2.51	No	No	0
129	R:R:L138	R:R:Y134	4.69	Yes	Yes	1
130	R:R:I143	R:R:L138	2.85	Yes	Yes	1
131	R:R:T139	R:R:V142	4.76	No	No	0
132	R:R:I146	R:R:V142	3.07	No	No	0
133	R:R:K145	R:R:M148	4.32	No	No	0
134	R:R:R153	R:R:V150	3.92	No	No	0
135	R:R:I159	R:R:V155	3.07	Yes	No	0
136	R:R:I159	R:R:L156	2.85	Yes	No	0
137	R:R:I159	R:R:P160	3.39	Yes	No	0
138	R:R:P160	R:R:Y200	4.17	No	Yes	0
139	R:R:F161	R:R:H183	14.71	Yes	Yes	0
140	R:R:F161	R:R:Y200	7.22	Yes	Yes	6
141	R:R:F161	R:R:G201	3.01	Yes	No	0
142	R:R:F161	R:R:V204	2.62	Yes	No	6
143	R:R:L165	R:R:V186	2.98	No	No	0
144	R:R:I176	R:R:P177	3.39	Yes	No	0
145	R:R:I176	R:R:L189	2.85	Yes	No	0
146	R:R:H178	R:R:T179	4.11	Yes	Yes	2
147	R:R:H178	R:R:Y180	9.8	Yes	Yes	2
148	R:R:E182	R:R:H178	2.46	No	Yes	2
149	R:R:H178	R:R:I276	6.63	Yes	No	0
150	R:R:N280	R:R:T179	5.85	Yes	Yes	2
151	R:R:E182	R:R:Y180	7.86	No	Yes	2
152	R:R:L283	R:R:Y180	8.21	No	Yes	0
153	R:R:C181	R:R:V186	3.42	Yes	No	2
154	R:R:H183	R:R:N197	3.83	Yes	Yes	0
155	R:R:H264	R:R:M184	11.82	No	No	0
156	R:R:A187	R:R:N197	3.13	No	Yes	0
157	R:R:I194	R:R:K195	8.72	No	No	0
158	R:R:I198	R:R:K195	4.36	No	No	0
159	R:R:I198	R:R:N197	7.08	No	Yes	0
160	R:R:V204	R:R:Y200	10.09	No	Yes	6
161	R:R:F203	R:R:L207	17.05	No	No	0
162	R:R:I208	R:R:V204	3.07	No	No	0
163	R:R:I208	R:R:V209	3.07	No	No	0
164	R:R:D212	R:R:Y254	4.6	No	Yes	0
165	R:R:V213	R:R:Y254	3.79	No	Yes	0
166	R:R:I214	R:R:L218	2.85	No	No	0
167	R:R:I216	R:R:Y220	2.42	No	Yes	0
168	R:R:I216	R:R:I250	4.42	No	No	1
169	R:R:I216	R:R:Y254	2.42	No	Yes	1
170	R:R:S219	R:R:Y220	2.54	No	Yes	0
171	R:R:C243	R:R:Y220	6.72	No	Yes	0
172	R:R:H246	R:R:Y220	8.71	Yes	Yes	0
173	R:R:I247	R:R:Y220	6.04	No	Yes	0
174	R:R:K238	R:R:S241	9.18	No	No	0
175	R:R:S245	R:R:Y294	3.82	No	Yes	1
176	R:R:H246	R:R:I250	6.63	Yes	No	1
177	R:R:H246	R:R:Y294	3.27	Yes	Yes	1
178	R:R:I247	R:R:L251	2.85	No	No	0
179	R:R:N290	R:R:V249	2.96	No	Yes	0
180	R:R:V249	R:R:Y294	2.52	Yes	Yes	0
181	R:R:I250	R:R:Y254	2.42	No	Yes	1
182	R:R:F253	R:R:Y254	6.19	Yes	Yes	0
183	R:R:F253	R:R:P286	2.89	Yes	No	0
184	R:R:P256	R:R:T255	3.5	No	No	0
185	R:R:P256	R:R:Y282	6.95	No	Yes	0
186	R:R:F258	R:R:L262	13.4	No	No	0
187	R:R:F259	R:R:T263	7.78	No	No	0
188	R:R:F259	R:R:L278	2.44	No	No	3
189	R:R:F259	R:R:Y282	22.69	No	Yes	3
190	R:R:S260	R:R:Y282	2.54	No	Yes	0
191	R:R:F261	R:R:R265	3.21	No	No	0
192	R:R:F266	R:R:L262	2.44	No	No	0
193	R:R:H264	R:R:R265	9.03	No	No	0
194	R:R:H268	R:R:H269	3.58	No	No	0
195	R:R:I270	R:R:P271	3.39	No	Yes	3
196	R:R:I270	R:R:I274	7.36	No	Yes	3
197	R:R:H275	R:R:I270	9.28	No	No	0
198	R:R:P271	R:R:Y273	5.56	Yes	No	3
199	R:R:I274	R:R:P271	3.39	Yes	Yes	3
200	R:R:I274	R:R:Y273	16.92	Yes	No	3
201	R:R:I274	R:R:L278	2.85	Yes	No	3
202	R:R:L278	R:R:Y282	5.86	No	Yes	3
203	R:R:L284	R:R:N280	2.75	Yes	Yes	2
204	R:R:L283	R:R:L284	2.77	No	Yes	0
205	R:R:L289	R:R:V285	4.47	No	Yes	0
206	R:R:P286	R:R:P287	5.84	No	No	0
207	R:R:L289	R:R:M288	2.83	No	No	0
208	R:R:D97	R:R:F96	2.39	No	Yes	0
209	R:R:I31	R:R:W28	2.35	No	No	0
210	R:R:L157	R:R:Y200	2.34	No	Yes	0
211	R:R:E59	R:R:Y62	2.24	No	No	0
212	R:R:F14	R:R:F96	2.14	No	Yes	0
213	R:R:F266	R:R:R265	2.14	No	No	0
214	R:R:G21	R:R:P20	2.03	No	Yes	0
215	R:R:P177	R:R:P20	1.95	No	Yes	0
216	R:R:P271	R:R:P272	1.95	Yes	No	0
217	R:R:A40	R:R:P287	1.87	No	No	0
218	R:R:G115	R:R:S114	1.86	No	No	0
219	R:R:G115	R:R:V150	1.84	No	No	0
220	R:R:G210	R:R:V209	1.84	No	No	0
221	R:R:G43	R:R:T46	1.82	No	No	0
222	R:R:A226	R:R:C129	1.81	No	No	0
223	R:R:P20	R:R:V17	1.77	Yes	No	0
224	R:R:P286	R:R:V285	1.77	No	Yes	0
225	R:R:G111	R:R:I208	1.76	No	No	0
226	R:R:G144	R:R:I143	1.76	No	Yes	0
227	R:R:G147	R:R:I146	1.76	No	No	0
228	R:R:G244	R:R:I247	1.76	No	No	0
229	R:R:G147	R:R:M67	1.75	No	No	0
230	R:R:G185	R:R:M184	1.75	No	No	0
231	R:R:G185	R:R:K188	1.74	No	No	0
232	R:R:G43	R:R:L42	1.71	No	No	0
233	R:R:A257	R:R:S260	1.71	No	No	0
234	R:R:I276	R:R:P20	1.69	No	Yes	0
235	R:R:E23	R:R:G21	1.64	No	No	0
236	R:R:L132	R:R:P131	1.64	No	No	0
237	R:R:C248	R:R:I293	1.64	No	No	0
238	R:R:S12	R:R:S13	1.63	No	No	0
239	R:R:A66	R:R:I51	1.62	No	No	0
240	R:R:A149	R:R:K145	1.61	No	No	0
241	R:R:S45	R:R:T46	1.6	No	No	0
242	R:R:S241	R:R:T242	1.6	No	No	0
243	R:R:C34	R:R:L84	1.59	No	No	0
244	R:R:G267	R:R:H275	1.59	No	No	0
245	R:R:A69	R:R:L48	1.58	No	No	0
246	R:R:A205	R:R:L206	1.58	No	No	0
247	R:R:A252	R:R:L289	1.58	No	No	0
248	R:R:E59	R:R:P60	1.57	No	Yes	0
249	R:R:I51	R:R:V50	1.54	No	No	0
250	R:R:I293	R:R:V249	1.54	No	Yes	0
251	R:R:K141	R:R:T139	1.5	No	No	0
252	R:R:L281	R:R:V285	1.49	No	Yes	0
253	R:R:I39	R:R:M288	1.46	No	No	0
254	R:R:E93	R:R:S13	1.44	No	No	0
255	R:R:K141	R:R:K145	1.44	No	No	0
256	R:R:I214	R:R:L211	1.43	No	No	0
257	R:R:I223	R:R:L240	1.43	No	No	0
258	R:R:I175	R:R:N174	1.42	No	No	0
259	R:R:A85	R:R:F89	1.39	No	No	0
260	R:R:P131	R:R:Y130	1.39	No	No	0
261	R:R:L207	R:R:L211	1.38	No	No	0
262	R:R:L164	R:R:N197	1.37	No	Yes	0
263	R:R:E93	R:R:L15	1.33	No	No	0
264	R:R:H183	R:R:M184	1.31	Yes	No	0
265	R:R:S219	R:R:Y125	1.27	No	Yes	0
266	R:R:T135	R:R:Y134	1.25	No	Yes	0
267	R:R:I27	R:R:W88	1.17	No	No	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community
1	R:R:L16	3.915	4	4
2	R:R:I19	4.08	4	0
3	R:R:P20	2.166	5	0
4	R:R:F33	4.3925	4	2
5	R:R:N44	7.45	4	0
6	R:R:P60	4.82667	6	1
7	R:R:F64	4.316	5	1
8	R:R:L73	6.3075	4	0
9	R:R:T79	3.4075	4	2
10	R:R:I80	5.658	5	0
11	R:R:F96	4.8075	4	0
12	R:R:Q102	3.6875	4	2
13	R:R:M103	3.365	4	2
14	R:R:I106	4.49	4	2
15	R:R:F109	5.39167	6	5
16	R:R:M112	4.0825	4	5
17	R:R:M120	3.958	5	1
18	R:R:D123	7.816	5	1
19	R:R:R124	6.786	5	1
20	R:R:Y125	3.6775	4	0
21	R:R:Y134	5.20167	6	1
22	R:R:L138	4.176	5	1
23	R:R:I143	2.838	5	1
24	R:R:I159	3.27	4	0
25	R:R:F161	6.89	4	6
26	R:R:I176	3.93	4	0
27	R:R:H178	5.75	4	2
28	R:R:T179	6.9	4	2
29	R:R:Y180	6.576	5	2
30	R:R:C181	4.2475	4	2
31	R:R:H183	5.474	5	0
32	R:R:N197	3.8525	4	0
33	R:R:Y200	5.955	4	6
34	R:R:Y220	5.286	5	0
35	R:R:H246	6.69167	6	1
36	R:R:V249	2.5	4	0
37	R:R:F253	6.3775	4	0
38	R:R:Y254	3.884	5	1
39	R:R:P271	3.5725	4	3
40	R:R:I274	7.63	4	3
41	R:R:N280	6.115	4	2
42	R:R:Y282	9.51	4	3
43	R:R:L284	3.4175	4	2
44	R:R:V285	2.6925	4	0
45	R:R:Y294	5.79167	6	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community
1	R:R:F14	R:R:I176	10.0592	3.77	No	Yes	0
2	R:R:I176	R:R:P177	24.7358	3.39	Yes	No	0
3	R:R:P177	R:R:P20	26.4154	1.95	No	Yes	0
4	R:R:P20	R:R:V17	13.7718	1.77	Yes	No	0
5	R:R:I175	R:R:V17	12.0629	3.07	No	No	0
6	R:R:I175	R:R:N174	10.3504	1.42	No	No	0
7	R:R:I176	R:R:L16	11.7296	5.71	Yes	Yes	0
8	R:R:I19	R:R:P20	36.731	3.39	Yes	Yes	0
9	R:R:I19	R:R:L22	32.0329	4.28	Yes	No	0
10	R:R:L22	R:R:Y273	30.3643	3.52	No	No	0
11	R:R:I276	R:R:P20	79.2498	1.69	No	Yes	0
12	R:R:H178	R:R:I276	80.5887	6.63	Yes	No	0
13	R:R:H178	R:R:T179	20.4205	4.11	Yes	Yes	2
14	R:R:N280	R:R:T179	19.7373	5.85	Yes	Yes	2
15	R:R:L284	R:R:N280	20.2154	2.75	Yes	Yes	2
16	R:R:I80	R:R:L284	42.3082	5.71	Yes	Yes	0
17	R:R:H178	R:R:Y180	59.5069	9.8	Yes	Yes	2
18	R:R:L283	R:R:Y180	20.4462	8.21	No	Yes	0
19	R:R:L283	R:R:L284	20.6715	2.77	No	Yes	0
20	R:R:Q102	R:R:Y180	20.7722	3.38	Yes	Yes	2
21	R:R:Q102	R:R:T79	32.1867	2.83	Yes	Yes	2
22	R:R:I80	R:R:T79	59.1717	3.04	Yes	Yes	0
23	R:R:I106	R:R:Y180	22.1734	3.63	Yes	Yes	2
24	R:R:I106	R:R:T79	26.7469	4.56	Yes	Yes	2
25	R:R:I80	R:R:Y37	100	13.3	Yes	No	0
26	R:R:T77	R:R:Y37	99.8425	6.24	No	No	0
27	R:R:L73	R:R:T77	99.6813	2.95	Yes	No	0
28	R:R:L73	R:R:N44	99.1758	12.36	Yes	Yes	0
29	R:R:D72	R:R:N44	97.2526	9.42	No	Yes	0
30	R:R:D72	R:R:P287	97.0401	9.66	No	No	0
31	R:R:P286	R:R:P287	96.6042	5.84	No	No	0
32	R:R:F253	R:R:P286	94.2048	2.89	Yes	No	0
33	R:R:F253	R:R:L117	40.885	2.44	Yes	No	0
34	R:R:L117	R:R:V249	40.4894	2.98	No	Yes	0
35	R:R:V249	R:R:Y294	38.7622	2.52	Yes	Yes	0
36	R:R:M120	R:R:Y294	28.5675	3.59	Yes	Yes	1
37	R:R:F64	R:R:M120	57.0672	4.98	Yes	Yes	1
38	R:R:F64	R:R:P60	18.8472	2.89	Yes	Yes	1
39	R:R:F253	R:R:Y254	52.7172	6.19	Yes	Yes	0
40	R:R:I250	R:R:Y254	39.1725	2.42	No	Yes	1
41	R:R:H246	R:R:I250	38.8556	6.63	Yes	No	1
42	R:R:H246	R:R:M120	30.6354	3.94	Yes	Yes	1
43	R:R:D123	R:R:M61	16.2921	9.7	Yes	No	0
44	R:R:M61	R:R:R124	17.2647	8.69	No	Yes	0
45	R:R:D123	R:R:F64	15.6272	7.17	Yes	Yes	1
46	R:R:D123	R:R:Y134	17.3325	10.34	Yes	Yes	1
47	R:R:D123	R:R:L138	12.0922	5.43	Yes	Yes	1
48	R:R:F64	R:R:I143	20.633	3.77	Yes	Yes	1
49	R:R:I143	R:R:Y63	12.8469	2.42	Yes	No	0
50	R:R:M67	R:R:Y63	11.5849	16.76	No	No	0
51	R:R:C181	R:R:Q102	12.7754	3.05	Yes	Yes	2
52	R:R:C181	R:R:M103	10.9676	3.24	Yes	Yes	2
53	R:R:H183	R:R:M103	10.768	3.94	Yes	Yes	0
54	R:R:V126	R:R:Y134	14.8488	2.52	No	Yes	1
55	R:R:L138	R:R:V126	19.4406	2.98	Yes	No	1
56	R:R:I137	R:R:V126	26.0033	3.07	No	No	0
57	R:R:I137	R:R:R133	17.3398	2.51	No	No	0
58	R:R:G147	R:R:M67	10.3247	1.75	No	No	0
59	R:R:I274	R:R:Y273	20.1659	16.92	Yes	No	3
60	R:R:I274	R:R:L278	13.433	2.85	Yes	No	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8W77

PDB Summary
PDB	8W77
Class	A
SubFamily	Olfactory receptors
Type	Olfactory
SubType	OR52C
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.61
Date	2023-12-20
D.O.I.	10.1038/s41467-023-43983-9

Net Summary
I_min	2.42
Number of Linked Nodes	238
Number of Links	267
Number of Hubs	45
Number of Links mediated by Hubs	158
Number of Communities	6
Number of Nodes involved in Communities	47
Number of Links involved in Communities	67

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	73268
Length Of Smallest Path	3
Average Path Length	20.7699
Length of Longest Path	38
Minimum Path Strength	1.385
Average Path Strength	5.51338
Maximum Path Strength	19.235
Minimum Path Correlation	0.7
Average Path Correlation	0.910065
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	28.2963
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	52.6566
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • organic cyclic compound binding • tetrapyrrole binding • heme binding • electron transfer activity • cation binding • transition metal ion binding • iron ion binding • ion binding • metal ion binding • small molecule binding
Gene Ontology	Biological Process	• cellular metabolic process • electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy
Gene Ontology	Cellular Component	• periplasmic space • cellular anatomical entity
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	-
Sequence	>8W77_Chain_R P S S F L L V I P G L E S V H I W I S I P F C A M Y L I A L L G N S T L L F V I K L H E P M Y Y F L A M L A A T D L V L S T S T I P K M L A I F W F N L K E I S F D A C L T Q M F F I H S F T G M E S G V L L A M A F D R Y V A I C Y P L R Y T T I L T N K V I G K I G M A V V L R A V L L V I P F P F L L K R L N I I P H T Y C E H M G V A K L I K V N I I Y G L F V A L L I V G L D V I L I A L S Y V L I L R A L K A L S T C G S H I C V I L A F Y T P A F F S F L T H R F G H H I P P Y I H I L L A N L Y L L V P P M L N P I I Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8HTI	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	Ocatnoic Acid	-	Gs/&β;1/&γ;2	2.97	2023-12-20	10.1038/s41467-023-43983-9
	8J46	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	-	-	-	3.66	2023-12-20	10.1038/s41467-023-43983-9
	8W77	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	-	-	-	3.61	2023-12-20	10.1038/s41467-023-43983-9

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8W77.zip

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