psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:N14	A:A:R13	6.03	No	No	0	3	4
2	A:A:K17	A:A:R20	11.14	No	No	0	4	3
3	A:A:A18	A:A:E21	3.02	No	No	0	4	2
4	A:A:Q19	B:B:D83	7.83	No	Yes	13	4	8
5	A:A:Q19	B:B:T86	9.92	No	Yes	13	4	6
6	A:A:Q19	B:B:N88	15.85	No	No	13	4	7
7	A:A:E27	A:A:N23	6.57	No	No	0	6	7
8	A:A:N23	B:B:N88	14.98	No	No	0	7	7
9	A:A:K25	A:A:K28	8.62	No	No	0	5	4
10	A:A:K25	A:A:Q29	4.07	No	No	0	5	4
11	A:A:I26	B:B:K89	8.72	No	Yes	0	9	9
12	A:A:E27	B:B:K89	14.85	No	Yes	0	6	9
13	A:A:D33	A:A:Q29	7.83	No	No	0	5	4
14	A:A:L30	B:B:K89	4.23	No	Yes	0	5	9
15	A:A:D33	B:B:K78	6.91	No	No	0	5	8
16	A:A:K34	B:B:L55	7.05	No	No	0	4	6
17	A:A:R42	A:A:Y37	14.4	No	Yes	0	9	4
18	A:A:Y37	B:B:L55	5.86	Yes	No	16	4	6
19	A:A:Y37	B:B:A56	5.34	Yes	No	16	4	7
20	A:A:Y37	B:B:D76	4.6	Yes	Yes	16	4	9
21	A:A:R38	R:R:P136	14.41	No	Yes	0	4	5
22	A:A:H220	A:A:T40	6.85	No	No	0	7	7
23	A:A:F219	A:A:H41	7.92	Yes	No	0	8	6
24	A:A:H41	A:A:T242	5.48	No	No	0	6	8
25	A:A:H41	A:A:I383	3.98	No	Yes	0	6	8
26	A:A:F222	A:A:R42	4.28	Yes	No	0	7	9
27	A:A:D240	A:A:R42	7.15	Yes	No	0	6	9
28	A:A:F219	A:A:L43	3.65	Yes	No	0	8	7
29	A:A:I245	A:A:L43	5.71	No	No	0	7	7
30	A:A:L44	A:A:L46	6.92	Yes	Yes	1	9	8
31	A:A:F238	A:A:L44	20.7	Yes	Yes	1	9	9
32	A:A:L44	A:A:V241	2.98	Yes	No	1	9	9
33	A:A:I244	A:A:L44	7.14	Yes	Yes	1	8	9
34	A:A:K53	A:A:L45	8.46	Yes	No	21	9	8
35	A:A:D223	A:A:L45	4.07	No	No	21	9	8
36	A:A:L46	A:A:R231	3.64	Yes	Yes	0	8	9
37	A:A:I235	A:A:L46	4.28	No	Yes	0	9	8
38	A:A:I244	A:A:L46	4.28	Yes	Yes	1	8	8
39	A:A:G47	A:A:K53	6.97	No	Yes	0	9	9
40	A:A:D252	A:A:N50	4.04	No	No	0	8	9
41	A:A:N50	A:A:R265	3.62	No	Yes	0	9	9
42	A:A:G52	A:A:T55	5.46	No	No	0	9	9
43	A:A:D223	A:A:K53	8.3	No	Yes	21	9	9
44	A:A:K53	A:A:V247	3.04	Yes	Yes	0	9	7
45	A:A:I56	A:A:V247	3.07	No	Yes	0	7	7
46	A:A:I56	A:A:N371	5.66	No	Yes	0	7	9
47	A:A:T210	A:A:V57	7.93	No	No	0	7	7
48	A:A:Q59	A:A:T369	8.5	No	No	0	9	9
49	A:A:F212	A:A:M60	8.71	No	No	0	9	9
50	A:A:A372	A:A:M60	3.22	No	No	0	8	9
51	A:A:F208	A:A:G226	3.01	No	No	0	5	9
52	A:A:M221	A:A:T210	7.53	No	No	0	8	7
53	A:A:H220	A:A:K211	11.79	No	No	0	7	4
54	A:A:F212	A:A:F219	10.72	No	Yes	0	9	8
55	A:A:F212	A:A:M221	7.46	No	No	0	9	8
56	A:A:N218	A:A:Q213	7.92	No	No	0	4	3
57	A:A:D215	A:A:V214	4.38	No	No	14	5	6
58	A:A:R373	A:A:V214	5.23	Yes	No	14	5	6
59	A:A:F376	A:A:V214	13.11	Yes	No	14	8	6
60	A:A:D215	A:A:R373	5.96	No	Yes	14	5	5
61	A:A:D215	A:A:F376	7.17	No	Yes	14	5	8
62	A:A:F219	A:A:V217	5.24	Yes	No	0	8	5
63	A:A:V217	R:R:M133	3.04	No	No	0	5	7
64	A:A:F219	A:A:F376	6.43	Yes	Yes	0	8	8
65	A:A:F222	A:A:H220	3.39	Yes	No	0	7	7
66	A:A:F222	A:A:F238	5.36	Yes	Yes	1	7	9
67	A:A:F222	B:B:W99	16.04	Yes	Yes	1	7	9
68	A:A:Q227	A:A:V224	5.73	Yes	No	2	9	9
69	A:A:V224	A:A:W234	13.48	No	No	2	9	9
70	A:A:G226	A:A:Q227	3.29	No	Yes	0	9	9
71	A:A:Q227	A:A:W234	4.38	Yes	No	2	9	9
72	A:A:Q227	B:B:N119	5.28	Yes	No	0	9	9
73	A:A:Q227	B:B:R145	3.5	Yes	Yes	2	9	8
74	A:A:E230	A:A:R228	12.79	No	No	2	9	9
75	A:A:R228	B:B:T164	5.17	No	No	0	9	6
76	A:A:R228	B:B:D186	8.34	No	Yes	2	9	9
77	A:A:E230	A:A:R232	12.79	No	No	0	9	8
78	A:A:E230	B:B:D186	6.5	No	Yes	2	9	9
79	A:A:R231	A:A:W234	7	Yes	No	0	9	9
80	A:A:L272	A:A:R231	6.07	No	Yes	0	8	9
81	A:A:R232	B:B:D228	15.48	No	Yes	0	8	9
82	A:A:K233	B:B:R145	4.95	Yes	Yes	2	9	8
83	A:A:K233	B:B:M188	11.52	Yes	No	2	9	8
84	A:A:K233	B:B:C204	4.85	Yes	No	2	9	7
85	A:A:K233	B:B:D228	9.68	Yes	Yes	2	9	9
86	A:A:K233	B:B:N230	6.99	Yes	No	2	9	9
87	A:A:K233	B:B:D246	5.53	Yes	No	2	9	9
88	A:A:I235	A:A:L282	4.28	No	Yes	0	9	9
89	A:A:Q236	A:A:W281	7.67	No	Yes	0	8	5
90	A:A:C237	B:B:Y59	6.72	No	Yes	1	8	8
91	A:A:C237	B:B:Q75	3.05	No	Yes	1	8	9
92	A:A:C237	B:B:M101	4.86	No	No	0	8	9
93	A:A:F238	A:A:V241	5.24	Yes	No	1	9	9
94	A:A:F238	B:B:W99	14.03	Yes	Yes	1	9	9
95	A:A:D240	A:A:N239	4.04	Yes	No	1	6	8
96	A:A:N239	B:B:K57	12.59	No	Yes	1	8	9
97	A:A:N239	B:B:W332	9.04	No	Yes	1	8	9
98	A:A:D240	B:B:K57	9.68	Yes	Yes	1	6	9
99	A:A:D240	B:B:Q75	5.22	Yes	Yes	1	6	9
100	A:A:I285	A:A:V241	3.07	No	No	0	7	9
101	A:A:C379	A:A:T242	5.07	No	No	0	8	8
102	A:A:A243	A:A:I288	3.25	No	No	0	8	9
103	A:A:I244	A:A:L282	5.71	Yes	Yes	0	8	9
104	A:A:I244	A:A:I285	4.42	Yes	No	0	8	7
105	A:A:I244	A:A:V287	3.07	Yes	No	1	8	6
106	A:A:I245	A:A:I375	5.89	No	No	0	7	9
107	A:A:F246	A:A:V248	6.55	Yes	No	0	9	7
108	A:A:F246	A:A:L272	7.31	Yes	No	0	9	8
109	A:A:F246	A:A:F273	4.29	Yes	Yes	1	9	9
110	A:A:F246	A:A:L289	4.87	Yes	Yes	1	9	9
111	A:A:F290	A:A:V247	3.93	Yes	Yes	0	9	7
112	A:A:N292	A:A:V247	4.43	Yes	Yes	0	9	7
113	A:A:A269	A:A:V248	3.39	No	No	0	9	7
114	A:A:F345	A:A:V248	3.93	Yes	No	0	8	7
115	A:A:D249	A:A:S251	10.31	No	No	22	8	9
116	A:A:D249	A:A:D252	10.65	No	No	22	8	8
117	A:A:D249	A:A:K293	8.3	No	No	0	8	9
118	A:A:L291	A:A:S250	4.5	No	No	0	8	6
119	A:A:I341	A:A:S250	3.1	No	No	0	8	6
120	A:A:D252	A:A:S251	5.89	No	No	22	8	9
121	A:A:L296	A:A:S251	9.01	No	No	0	6	9
122	A:A:K300	A:A:Y253	10.75	No	Yes	0	9	8
123	A:A:V301	A:A:Y253	3.79	Yes	Yes	0	7	8
124	A:A:I308	A:A:Y253	10.88	No	Yes	0	7	8
125	A:A:Y253	A:A:Y311	8.94	Yes	Yes	0	8	6
126	A:A:N264	A:A:Y311	8.14	No	Yes	0	9	6
127	A:A:E268	A:A:R265	12.79	No	Yes	0	9	9
128	A:A:L266	A:A:L270	4.15	No	Yes	0	8	6
129	A:A:F312	A:A:L266	4.87	Yes	No	0	8	8
130	A:A:I341	A:A:L266	7.14	No	No	0	8	8
131	A:A:L270	A:A:Q267	3.99	Yes	No	0	6	4
132	A:A:N271	A:A:Q267	7.92	No	No	0	5	4
133	A:A:E344	A:A:L270	6.63	No	Yes	0	5	6
134	A:A:F345	A:A:L270	8.53	Yes	Yes	0	8	6
135	A:A:I348	A:A:L270	4.28	No	Yes	0	4	6
136	A:A:I276	A:A:L272	4.28	No	No	0	8	8
137	A:A:F273	A:A:W277	7.02	Yes	Yes	1	9	6
138	A:A:F273	A:A:V287	5.24	Yes	No	1	9	6
139	A:A:F273	A:A:L289	3.65	Yes	Yes	1	9	9
140	A:A:F273	A:A:F345	8.57	Yes	Yes	1	9	8
141	A:A:F273	A:A:I348	5.02	Yes	No	0	9	4
142	A:A:C359	A:A:F273	5.59	Yes	Yes	1	5	9
143	A:A:K274	A:A:N278	6.99	No	No	0	5	8
144	A:A:I348	A:A:K274	5.82	No	No	0	4	5
145	A:A:I276	A:A:L282	5.71	No	Yes	0	8	9
146	A:A:V287	A:A:W277	4.9	No	Yes	1	6	6
147	A:A:S349	A:A:W277	9.88	Yes	Yes	1	7	6
148	A:A:H357	A:A:W277	25.39	No	Yes	0	7	6
149	A:A:C359	A:A:W277	3.92	Yes	Yes	1	5	6
150	A:A:N278	A:A:S352	2.98	No	No	0	8	5
151	A:A:L282	A:A:N279	12.36	Yes	No	0	9	8
152	A:A:R280	A:A:W281	24.99	No	Yes	0	5	5
153	A:A:R280	A:A:R283	4.26	No	No	0	5	3
154	A:A:R280	B:B:F292	3.21	No	No	0	5	4
155	A:A:W281	B:B:D290	10.05	Yes	Yes	1	5	6
156	A:A:W281	B:B:R314	14.99	Yes	Yes	1	5	8
157	A:A:R283	A:A:R356	8.53	No	No	0	3	2
158	A:A:I382	A:A:S286	9.29	No	No	0	6	8
159	A:A:F290	A:A:I288	5.02	Yes	No	0	9	9
160	A:A:D378	A:A:I288	12.59	No	No	0	7	9
161	A:A:L289	A:A:L291	6.92	Yes	No	0	9	8
162	A:A:F345	A:A:L289	8.53	Yes	Yes	1	8	9
163	A:A:C359	A:A:L289	4.76	Yes	Yes	1	5	9
164	A:A:F290	A:A:T364	9.08	Yes	Yes	17	9	9
165	A:A:F290	A:A:N371	6.04	Yes	Yes	17	9	9
166	A:A:F290	A:A:I375	5.02	Yes	No	0	9	9
167	A:A:F363	A:A:L291	3.65	Yes	No	0	5	8
168	A:A:N292	A:A:T364	7.31	Yes	Yes	0	9	9
169	A:A:K293	A:A:L296	7.05	No	No	0	9	6
170	A:A:K338	A:A:Q294	10.85	Yes	No	1	5	6
171	A:A:F363	A:A:Q294	12.88	Yes	No	1	5	6
172	A:A:C365	A:A:D295	9.34	No	No	0	8	9
173	A:A:L297	A:A:V301	2.98	No	Yes	0	8	7
174	A:A:R333	A:A:V301	14.38	No	Yes	0	5	7
175	A:A:V301	A:A:V334	4.81	Yes	Yes	0	7	4
176	A:A:D331	A:A:L302	4.07	Yes	No	1	4	2
177	A:A:L302	A:A:V334	2.98	No	Yes	1	2	4
178	A:A:S306	A:A:Y311	3.82	No	Yes	0	7	6
179	A:A:E309	A:A:K307	5.4	No	No	0	4	6
180	A:A:F315	A:A:I308	13.82	Yes	No	0	6	7
181	A:A:E309	A:A:F315	8.16	No	Yes	0	4	6
182	A:A:F312	A:A:F340	4.29	Yes	Yes	18	8	7
183	A:A:E344	A:A:F312	12.83	No	Yes	18	5	8
184	A:A:E314	A:A:P313	7.86	Yes	No	0	6	6
185	A:A:E314	A:A:R317	3.49	Yes	No	0	6	2
186	A:A:F315	A:A:R336	22.45	Yes	No	0	6	5
187	A:A:F315	A:A:F340	21.43	Yes	Yes	0	6	7
188	A:A:P321	A:A:Y318	5.56	No	No	0	5	6
189	A:A:F340	A:A:Y318	12.38	Yes	No	0	7	6
190	A:A:D343	A:A:Y318	14.94	No	No	0	3	6
191	A:A:P321	A:A:T320	3.5	No	No	0	5	1
192	A:A:R336	A:A:T320	3.88	No	No	0	5	1
193	A:A:D323	A:A:P321	4.83	No	No	0	4	5
194	A:A:A324	A:A:Y339	8.01	No	Yes	0	3	3
195	A:A:P326	A:A:T335	8.74	No	No	0	1	4
196	A:A:E327	A:A:P328	11	No	No	0	4	1
197	A:A:E330	A:A:V334	8.56	Yes	Yes	1	3	4
198	A:A:E330	A:A:T335	11.29	Yes	No	0	3	4
199	A:A:E330	A:A:K338	9.45	Yes	Yes	1	3	5
200	A:A:D331	A:A:P332	6.44	Yes	No	0	4	1
201	A:A:D331	A:A:R333	10.72	Yes	No	0	4	5
202	A:A:D331	A:A:V334	5.84	Yes	Yes	1	4	4
203	A:A:K338	A:A:V334	3.04	Yes	Yes	1	5	4
204	A:A:T335	A:A:Y339	3.75	No	Yes	0	4	3
205	A:A:F363	A:A:K338	11.17	Yes	Yes	1	5	5
206	A:A:R342	A:A:Y339	11.32	Yes	Yes	1	4	3
207	A:A:F363	A:A:Y339	11.35	Yes	Yes	1	5	3
208	A:A:E344	A:A:F340	11.66	No	Yes	18	5	7
209	A:A:L346	A:A:R342	4.86	No	Yes	1	4	4
210	A:A:P361	A:A:R342	5.76	No	Yes	1	5	4
211	A:A:F363	A:A:R342	7.48	Yes	Yes	1	5	4
212	A:A:D343	A:A:R347	5.96	No	No	0	3	4
213	A:A:L346	A:A:S349	3	No	Yes	1	4	7
214	A:A:L346	A:A:P361	6.57	No	No	1	4	5
215	A:A:C359	A:A:S349	3.44	Yes	Yes	1	5	7
216	A:A:G353	A:A:H357	3.18	No	No	0	4	7
217	A:A:D354	A:A:R356	11.91	No	No	0	3	2
218	A:A:G355	A:A:Y358	5.79	No	No	0	2	4
219	A:A:H357	A:A:R356	3.39	No	No	0	7	2
220	A:A:Y358	A:A:Y360	2.98	No	Yes	0	4	8
221	A:A:R385	A:A:Y358	8.23	No	No	0	5	4
222	A:A:C359	A:A:P361	3.77	Yes	No	1	5	5
223	A:A:H362	A:A:Y360	3.27	No	Yes	9	9	8
224	A:A:D378	A:A:Y360	11.49	No	Yes	9	7	8
225	A:A:D381	A:A:Y360	5.75	No	Yes	9	8	8
226	A:A:I382	A:A:Y360	4.84	No	Yes	0	6	8
227	A:A:H362	A:A:R374	9.03	No	No	0	9	4
228	A:A:D378	A:A:H362	8.82	No	No	9	7	9
229	A:A:D368	A:A:T364	8.67	Yes	Yes	17	9	9
230	A:A:N371	A:A:T364	7.31	Yes	Yes	17	9	9
231	A:A:D368	A:A:E370	6.5	Yes	No	0	9	4
232	A:A:D368	A:A:N371	13.46	Yes	Yes	17	9	9
233	A:A:E370	A:A:R374	3.49	No	No	0	4	4
234	A:A:N371	A:A:R374	3.62	Yes	No	0	9	4
235	A:A:F376	A:A:R373	3.21	Yes	Yes	14	8	5
236	A:A:N377	A:A:R373	4.82	No	Yes	14	4	5
237	A:A:F376	A:A:N377	4.83	Yes	No	14	8	4
238	A:A:F376	R:R:M133	7.46	Yes	No	0	8	7
239	A:A:Q384	A:A:R380	3.5	No	No	9	6	7
240	A:A:R380	R:R:P132	4.32	No	Yes	9	7	9
241	A:A:R380	R:R:M133	4.96	No	No	0	7	7
242	A:A:D381	A:A:R385	10.72	No	No	9	8	5
243	A:A:D381	R:R:K218	13.83	No	No	9	8	7
244	A:A:I383	A:A:M386	4.37	Yes	No	0	8	3
245	A:A:H387	A:A:I383	6.63	Yes	Yes	9	8	8
246	A:A:I383	R:R:P132	3.39	Yes	Yes	9	8	9
247	A:A:Q384	R:R:P132	6.32	No	Yes	9	6	9
248	A:A:Q384	R:R:K218	8.14	No	No	9	6	7
249	A:A:R385	R:R:K218	4.95	No	No	9	5	7
250	A:A:H387	A:A:Q390	4.95	Yes	No	0	8	4
251	A:A:H387	R:R:A128	4.39	Yes	No	0	8	8
252	A:A:H387	R:R:P132	3.05	Yes	Yes	9	8	9
253	A:A:L388	A:A:L393	5.54	Yes	No	0	8	8
254	A:A:L388	A:A:L394	5.54	Yes	Yes	23	8	8
255	A:A:L388	R:R:V129	4.47	Yes	No	0	8	9
256	A:A:L388	R:R:A215	3.15	Yes	No	23	8	8
257	A:A:L394	A:A:R389	3.64	Yes	No	0	8	4
258	A:A:Q390	A:A:Y391	13.53	No	No	0	4	4
259	A:A:Y391	R:R:R125	16.46	No	Yes	0	4	9
260	A:A:Y391	R:R:A128	4	No	No	0	4	8
261	A:A:E392	R:R:R332	6.98	No	No	0	6	9
262	A:A:L393	R:R:I211	4.28	No	No	0	8	9
263	A:A:L394	R:R:A215	3.15	Yes	No	23	8	8
264	A:A:L394	R:R:A219	4.73	Yes	No	0	8	6
265	B:B:D5	B:B:Q9	13.05	No	No	0	1	3
266	B:B:E10	B:B:Q6	3.82	No	No	0	8	1
267	B:B:L7	G:G:A12	3.15	No	No	0	8	5
268	B:B:L7	G:G:R13	9.72	No	No	0	8	6
269	B:B:L7	G:G:V16	2.98	No	No	0	8	7
270	B:B:E12	B:B:R8	3.49	No	No	0	4	3
271	B:B:L14	G:G:L19	4.15	No	Yes	0	8	9
272	B:B:L14	G:G:K20	4.23	No	No	0	8	6
273	B:B:K15	G:G:L19	8.46	No	Yes	0	6	9
274	B:B:Q17	G:G:A23	4.55	No	No	0	4	8
275	B:B:I18	B:B:R22	7.52	Yes	No	3	7	6
276	B:B:I18	G:G:E22	16.4	Yes	Yes	3	7	9
277	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
278	B:B:I18	G:G:R27	7.52	Yes	Yes	3	7	8
279	B:B:A21	G:G:R27	4.15	No	Yes	0	4	8
280	B:B:Q259	B:B:R22	8.18	Yes	No	0	6	6
281	B:B:R22	G:G:E22	4.65	No	Yes	3	6	9
282	B:B:C25	B:B:Q259	4.58	No	Yes	0	3	6
283	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
284	B:B:A28	B:B:D27	4.63	No	No	0	4	8
285	B:B:D27	G:G:S31	8.83	No	No	0	8	9
286	B:B:S31	B:B:T29	3.2	No	No	0	1	3
287	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
288	B:B:L30	B:B:S31	3	No	No	1	5	1
289	B:B:L30	B:B:M262	7.07	No	Yes	1	5	4
290	B:B:M262	B:B:S31	6.13	Yes	No	1	4	1
291	B:B:L300	B:B:T34	11.79	No	Yes	1	6	5
292	B:B:T34	G:G:M38	3.01	Yes	No	1	5	4
293	B:B:I37	B:B:R283	3.76	No	Yes	0	2	9
294	B:B:I37	G:G:E42	5.47	No	No	0	2	1
295	B:B:D38	B:B:P39	4.83	No	No	0	1	1
296	B:B:K301	B:B:P39	3.35	No	No	0	5	1
297	B:B:I43	B:B:V40	4.61	No	No	0	3	3
298	B:B:R283	B:B:V40	6.54	Yes	No	1	9	3
299	B:B:D298	B:B:V40	5.84	No	No	1	9	3
300	B:B:Q44	B:B:R42	12.85	No	No	0	4	2
301	B:B:A305	B:B:I43	3.25	No	No	0	4	3
302	B:B:L308	B:B:M45	4.24	No	No	0	7	4
303	B:B:T47	B:B:T50	4.71	No	No	6	3	3
304	B:B:K337	B:B:T47	13.51	Yes	No	6	6	3
305	B:B:T47	B:B:W339	9.7	No	Yes	6	3	9
306	B:B:N340	B:B:R48	10.85	No	No	0	9	7
307	B:B:R49	B:B:T87	5.17	No	No	0	7	5
308	B:B:R52	B:B:T50	10.35	No	No	6	7	3
309	B:B:K337	B:B:T50	12.01	Yes	No	6	6	3
310	B:B:L51	B:B:L70	4.15	Yes	No	7	9	5
311	B:B:L51	B:B:W82	18.22	Yes	Yes	7	9	9
312	B:B:L336	B:B:L51	5.54	No	Yes	0	7	9
313	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
314	B:B:F335	B:B:R52	8.55	Yes	No	6	4	7
315	B:B:R52	R:R:Y57	11.32	No	Yes	6	7	5
316	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
317	B:B:H54	B:B:S72	9.76	Yes	No	7	9	9
318	B:B:H54	B:B:S74	15.34	Yes	No	0	9	9
319	B:B:H54	B:B:I80	11.93	Yes	No	7	9	8
320	B:B:H54	B:B:W82	3.17	Yes	Yes	7	9	9
321	B:B:D76	B:B:L55	14.93	Yes	No	16	9	6
322	B:B:A56	B:B:D76	3.09	No	Yes	16	7	9
323	B:B:K57	B:B:Y59	5.97	Yes	Yes	1	9	8
324	B:B:K57	B:B:Q75	9.49	Yes	Yes	1	9	9
325	B:B:K57	B:B:W332	25.53	Yes	Yes	1	9	9
326	B:B:C317	B:B:I58	3.27	Yes	No	0	7	9
327	B:B:Q75	B:B:Y59	15.78	Yes	Yes	1	9	8
328	B:B:W332	B:B:Y59	9.65	Yes	Yes	1	9	8
329	B:B:A60	B:B:C103	3.61	No	No	0	7	8
330	B:B:M61	B:B:W63	6.98	Yes	Yes	7	6	7
331	B:B:C317	B:B:M61	3.24	Yes	Yes	0	7	6
332	B:B:G319	B:B:M61	5.24	No	Yes	0	5	6
333	B:B:A328	B:B:M61	3.22	No	Yes	7	5	6
334	B:B:H62	B:B:R150	11.28	No	No	0	6	6
335	B:B:L70	B:B:W63	10.25	No	Yes	7	5	7
336	B:B:S84	B:B:W63	4.94	No	Yes	0	5	7
337	B:B:T321	B:B:W63	12.13	Yes	Yes	7	7	7
338	B:B:A328	B:B:W63	3.89	No	Yes	7	5	7
339	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
340	B:B:D322	B:B:T65	4.34	No	No	0	1	1
341	B:B:D66	B:B:R68	9.53	No	No	0	8	5
342	B:B:S67	B:B:T321	7.99	No	Yes	7	5	7
343	B:B:D323	B:B:S67	8.83	No	No	7	7	5
344	B:B:D83	B:B:R68	13.1	Yes	No	13	8	5
345	B:B:R68	B:B:Y85	14.4	No	No	13	5	4
346	B:B:L69	B:B:V90	2.98	No	No	0	5	5
347	B:B:L69	B:B:Y105	7.03	No	Yes	0	5	6
348	B:B:L70	B:B:W82	6.83	No	Yes	7	5	9
349	B:B:L79	B:B:V71	4.47	Yes	No	0	7	8
350	B:B:I81	B:B:V71	4.61	No	No	0	7	8
351	B:B:V71	B:B:Y105	6.31	No	Yes	0	8	6
352	B:B:S72	B:B:W82	7.41	No	Yes	7	9	9
353	B:B:L336	B:B:S72	3	No	No	0	7	9
354	B:B:A73	B:B:V100	3.39	No	No	0	9	9
355	B:B:A73	B:B:C103	3.61	No	No	0	9	8
356	B:B:D76	B:B:S74	7.36	Yes	No	0	9	9
357	B:B:Q75	B:B:W99	13.14	Yes	Yes	1	9	9
358	B:B:D76	B:B:K78	11.06	Yes	No	0	9	8
359	B:B:L79	B:B:L95	4.15	Yes	Yes	12	7	8
360	B:B:C103	B:B:L79	3.17	No	Yes	0	8	7
361	B:B:L79	B:B:V112	2.98	Yes	Yes	12	7	8
362	B:B:C114	B:B:L79	6.35	No	Yes	12	8	7
363	B:B:I80	B:B:W82	15.27	No	Yes	7	8	9
364	B:B:H91	B:B:I81	6.63	No	No	0	5	7
365	B:B:I81	B:B:L126	4.28	No	Yes	0	7	5
366	B:B:K89	B:B:W82	11.6	Yes	Yes	0	9	9
367	B:B:D83	B:B:Y85	3.45	Yes	No	13	8	4
368	B:B:D83	B:B:T86	8.67	Yes	Yes	13	8	6
369	B:B:S84	B:B:Y85	5.09	No	No	0	5	4
370	B:B:N88	B:B:T86	10.24	No	Yes	13	7	6
371	B:B:H91	B:B:V90	5.54	No	No	0	5	5
372	B:B:H91	B:B:V133	4.15	No	No	0	5	4
373	B:B:I93	B:B:P94	3.39	No	No	0	7	5
374	B:B:I93	B:B:Y124	6.04	No	Yes	0	7	6
375	B:B:I93	B:B:V133	7.68	No	No	0	7	4
376	B:B:L95	B:B:V100	4.47	Yes	No	12	8	9
377	B:B:C114	B:B:L95	6.35	No	Yes	12	8	8
378	B:B:L95	B:B:Y124	5.86	Yes	Yes	0	8	6
379	B:B:E138	B:B:R96	3.49	No	No	0	6	6
380	B:B:D118	B:B:S97	10.31	No	No	0	9	8
381	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
382	B:B:L117	B:B:W99	7.97	No	Yes	0	9	9
383	B:B:C114	B:B:V100	3.42	No	No	12	8	9
384	B:B:G116	B:B:M101	5.24	No	No	0	9	9
385	B:B:M101	B:B:R145	9.93	No	Yes	0	9	8
386	B:B:C148	B:B:T102	3.38	No	No	0	6	8
387	B:B:C149	B:B:T102	5.07	Yes	No	0	8	8
388	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
389	B:B:V112	B:B:Y105	3.79	Yes	Yes	12	8	6
390	B:B:L126	B:B:Y105	4.69	Yes	Yes	12	5	6
391	B:B:A106	B:B:F151	5.55	No	Yes	0	6	9
392	B:B:N110	B:B:S108	8.94	No	No	0	4	6
393	B:B:D154	B:B:S108	8.83	No	No	0	6	6
394	B:B:N110	B:B:Y111	4.65	No	Yes	0	4	4
395	B:B:I123	B:B:Y111	3.63	Yes	Yes	0	6	4
396	B:B:N125	B:B:Y111	10.47	No	Yes	24	4	4
397	B:B:S136	B:B:Y111	5.09	No	Yes	24	4	4
398	B:B:D154	B:B:Y111	8.05	No	Yes	0	6	4
399	B:B:V112	B:B:Y124	3.79	Yes	Yes	0	8	6
400	B:B:L126	B:B:V112	5.96	Yes	Yes	12	5	8
401	B:B:G115	B:B:L146	3.42	No	Yes	0	9	7
402	B:B:E138	B:B:I120	5.47	No	No	0	6	6
403	B:B:C121	B:B:L139	6.35	Yes	No	0	8	9
404	B:B:C121	B:B:L146	3.17	Yes	Yes	2	8	7
405	B:B:C121	B:B:C149	5.46	Yes	Yes	2	8	8
406	B:B:C121	B:B:T159	3.38	Yes	Yes	2	8	9
407	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
408	B:B:E138	B:B:S122	5.75	No	No	0	6	8
409	B:B:I123	B:B:L139	4.28	Yes	No	0	6	9
410	B:B:F151	B:B:I123	3.77	Yes	Yes	0	9	6
411	B:B:I123	B:B:I171	5.89	Yes	No	0	6	6
412	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
413	B:B:N125	B:B:S136	2.98	No	No	24	4	4
414	B:B:L126	B:B:V133	4.47	Yes	No	0	5	4
415	B:B:E130	B:B:T128	11.29	No	No	0	3	3
416	B:B:E130	B:B:N132	3.94	No	No	0	3	3
417	B:B:R134	B:B:V135	9.15	No	No	0	3	4
418	B:B:R137	B:B:S136	3.95	No	No	0	5	4
419	B:B:L139	B:B:W169	18.22	No	Yes	0	9	8
420	B:B:H142	B:B:L146	3.86	Yes	Yes	2	9	7
421	B:B:H142	B:B:T159	8.21	Yes	Yes	2	9	9
422	B:B:H142	B:B:S161	15.34	Yes	Yes	2	9	9
423	B:B:D163	B:B:H142	5.04	Yes	Yes	2	9	9
424	B:B:H142	B:B:T165	5.48	Yes	No	2	9	7
425	B:B:A167	B:B:H142	4.39	No	Yes	2	4	9
426	B:B:H142	B:B:W169	3.17	Yes	Yes	2	9	8
427	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
428	B:B:G162	B:B:R145	6	No	Yes	2	9	8
429	B:B:D186	B:B:R145	7.15	Yes	Yes	2	9	8
430	B:B:M188	B:B:R145	6.2	No	Yes	2	8	8
431	B:B:C149	B:B:L146	3.17	Yes	Yes	2	8	7
432	B:B:L146	B:B:T159	5.9	Yes	Yes	2	7	9
433	B:B:S147	B:B:S160	4.89	No	No	0	9	6
434	B:B:C148	B:B:R150	6.96	No	No	0	6	6
435	B:B:C148	B:B:L190	9.52	No	No	0	6	5
436	B:B:C149	B:B:T159	3.38	Yes	Yes	2	8	9
437	B:B:L192	B:B:R150	4.86	Yes	No	0	5	6
438	B:B:F151	B:B:I157	10.05	Yes	Yes	0	9	7
439	B:B:L152	B:B:Q156	5.32	Yes	Yes	5	3	5
440	B:B:L152	B:B:V158	4.47	Yes	Yes	5	3	5
441	B:B:L152	B:B:L168	4.15	Yes	Yes	5	3	6
442	B:B:L152	B:B:L192	4.15	Yes	Yes	5	3	5
443	B:B:L152	B:B:T196	4.42	Yes	No	5	3	1
444	B:B:D153	B:B:Q156	5.22	No	Yes	0	5	5
445	B:B:D170	B:B:N155	10.77	Yes	No	5	9	3
446	B:B:I171	B:B:N155	4.25	No	No	0	6	3
447	B:B:E172	B:B:N155	10.52	No	No	5	6	3
448	B:B:L168	B:B:Q156	5.32	Yes	Yes	5	6	5
449	B:B:D170	B:B:Q156	5.22	Yes	Yes	5	9	5
450	B:B:I157	B:B:T159	3.04	Yes	Yes	2	7	9
451	B:B:I157	B:B:W169	3.52	Yes	Yes	2	7	8
452	B:B:I157	B:B:I171	5.89	Yes	No	0	7	6
453	B:B:L190	B:B:V158	2.98	No	Yes	0	5	5
454	B:B:L192	B:B:V158	2.98	Yes	Yes	5	5	5
455	B:B:F199	B:B:V158	6.55	Yes	Yes	5	9	5
456	B:B:T159	B:B:W169	9.7	Yes	Yes	2	9	8
457	B:B:S160	B:B:V187	4.85	No	No	0	6	9
458	B:B:L190	B:B:S160	9.01	No	No	0	5	6
459	B:B:G162	B:B:S161	3.71	No	Yes	2	9	9
460	B:B:D163	B:B:S161	5.89	Yes	Yes	2	9	9
461	B:B:D186	B:B:G162	3.35	Yes	No	2	9	9
462	B:B:D163	B:B:T165	14.45	Yes	No	2	9	7
463	B:B:T165	B:B:T181	4.71	No	No	0	7	2
464	B:B:C166	B:B:F180	4.19	No	Yes	5	8	7
465	B:B:C166	B:B:F199	5.59	No	Yes	5	8	9
466	B:B:C166	B:B:S201	3.44	No	Yes	5	8	9
467	B:B:A167	B:B:W169	5.19	No	Yes	2	4	8
468	B:B:A167	B:B:Q176	3.03	No	Yes	2	4	4
469	B:B:L168	B:B:T178	5.9	Yes	No	0	6	4
470	B:B:L168	B:B:V213	4.47	Yes	No	0	6	4
471	B:B:Q176	B:B:W169	15.33	Yes	Yes	2	4	8
472	B:B:D170	B:B:E172	6.5	Yes	No	5	9	6
473	B:B:D170	B:B:T173	5.78	Yes	No	0	9	5
474	B:B:Q175	B:B:T173	7.09	No	No	0	4	5
475	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
476	B:B:T177	B:B:T178	3.14	No	No	0	4	4
477	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
478	B:B:F180	B:B:F199	11.79	Yes	Yes	5	7	9
479	B:B:F180	B:B:W211	18.04	Yes	Yes	5	7	8
480	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
481	B:B:H183	B:B:V187	5.54	Yes	No	5	9	9
482	B:B:H183	B:B:S201	5.58	Yes	Yes	5	9	9
483	B:B:A203	B:B:H183	8.78	No	Yes	5	8	9
484	B:B:D205	B:B:H183	7.56	Yes	Yes	5	9	9
485	B:B:H183	B:B:K209	18.34	Yes	Yes	5	9	6
486	B:B:H183	B:B:W211	4.23	Yes	Yes	5	9	8
487	B:B:D205	B:B:T184	10.12	Yes	No	0	9	3
488	B:B:D205	B:B:G185	5.03	Yes	No	0	9	5
489	B:B:C204	B:B:D186	4.67	No	Yes	2	7	9
490	B:B:S201	B:B:V187	3.23	Yes	No	5	9	9
491	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
492	B:B:C233	B:B:S191	3.44	No	No	0	3	8
493	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
494	B:B:L192	B:B:T196	4.42	Yes	No	5	5	1
495	B:B:F199	B:B:L192	3.65	Yes	Yes	5	9	5
496	B:B:A193	B:B:D195	4.63	No	No	0	4	5
497	B:B:A193	B:B:F234	4.16	No	Yes	0	4	5
498	B:B:G238	B:B:P194	4.06	No	No	0	7	4
499	B:B:D195	B:B:R197	3.57	No	Yes	0	5	5
500	B:B:L198	B:B:R197	18.22	No	Yes	3	3	5
501	B:B:D212	B:B:R197	8.34	Yes	Yes	3	9	5
502	B:B:R197	B:B:R214	6.4	Yes	No	3	5	9
503	B:B:L198	B:B:L210	12.46	No	Yes	3	3	5
504	B:B:D212	B:B:L198	4.07	Yes	No	3	9	3
505	B:B:F199	B:B:W211	8.02	Yes	Yes	5	9	8
506	B:B:L210	B:B:V200	4.47	Yes	Yes	3	5	6
507	B:B:I232	B:B:V200	4.61	Yes	Yes	3	8	6
508	B:B:F234	B:B:V200	14.42	Yes	Yes	0	5	6
509	B:B:F241	B:B:V200	14.42	Yes	Yes	3	6	6
510	B:B:S201	B:B:W211	6.18	Yes	Yes	5	9	8
511	B:B:G202	B:B:I229	3.53	No	Yes	0	6	7
512	B:B:A203	B:B:D205	4.63	No	Yes	5	8	9
513	B:B:C204	B:B:D228	10.89	No	Yes	2	7	9
514	B:B:D205	B:B:S207	10.31	Yes	No	0	9	5
515	B:B:K209	B:B:S207	3.06	Yes	No	0	6	5
516	B:B:K209	B:B:W211	11.6	Yes	Yes	5	6	8
517	B:B:C218	B:B:K209	6.47	No	Yes	5	5	6
518	B:B:K209	B:B:T221	16.52	Yes	No	0	6	7
519	B:B:L210	B:B:R219	3.64	Yes	No	3	5	5
520	B:B:L210	B:B:Q220	5.32	Yes	Yes	3	5	7
521	B:B:L210	B:B:L255	8.3	Yes	No	3	5	6
522	B:B:C218	B:B:W211	11.75	No	Yes	5	5	8
523	B:B:D212	B:B:R214	5.96	Yes	No	3	9	9
524	B:B:D212	B:B:E215	10.39	Yes	No	3	9	3
525	B:B:D212	B:B:R219	13.1	Yes	No	3	9	5
526	B:B:E215	B:B:M217	4.06	No	No	0	3	3
527	B:B:E215	B:B:R219	11.63	No	No	3	3	5
528	B:B:F222	B:B:Q220	9.37	Yes	Yes	3	8	7
529	B:B:L255	B:B:Q220	5.32	No	Yes	3	6	7
530	B:B:D258	B:B:Q220	7.83	Yes	Yes	3	7	7
531	B:B:Q220	G:G:I25	5.49	Yes	No	0	7	2
532	B:B:T221	G:G:Q18	5.67	No	No	0	7	9
533	B:B:F222	B:B:F241	10.72	Yes	Yes	3	8	6
534	B:B:F222	B:B:F253	10.72	Yes	Yes	3	8	6
535	B:B:D258	B:B:F222	4.78	Yes	Yes	3	7	8
536	B:B:G224	B:B:T223	3.64	No	No	0	6	2
537	B:B:H225	B:B:I229	10.61	Yes	Yes	3	9	7
538	B:B:H225	B:B:T243	9.58	Yes	Yes	3	9	8
539	B:B:H225	B:B:S245	13.95	Yes	No	3	9	9
540	B:B:H225	B:B:R251	10.16	Yes	Yes	3	9	8
541	B:B:D247	B:B:E226	12.99	Yes	No	0	9	3
542	B:B:D247	B:B:S227	5.89	Yes	No	0	9	6
543	B:B:D228	B:B:D246	6.65	Yes	No	2	9	9
544	B:B:I229	B:B:T243	4.56	Yes	Yes	3	7	8
545	B:B:I229	B:B:S245	6.19	Yes	No	3	7	9
546	B:B:D246	B:B:N230	10.77	No	No	2	9	9
547	B:B:A231	B:B:V276	3.39	No	No	0	5	6
548	B:B:F241	B:B:I232	8.79	Yes	Yes	3	6	8
549	B:B:I232	B:B:T243	4.56	Yes	Yes	3	8	8
550	B:B:C233	B:B:V276	3.42	No	No	0	3	6
551	B:B:C233	B:B:F278	4.19	No	Yes	0	3	7
552	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
553	B:B:F235	B:B:P236	11.56	Yes	Yes	10	6	7
554	B:B:F235	B:B:N237	9.67	Yes	Yes	10	6	5
555	B:B:A240	B:B:F235	4.16	No	Yes	10	6	6
556	B:B:F235	B:B:F278	9.65	Yes	Yes	10	6	7
557	B:B:F235	B:B:G282	4.52	Yes	No	10	6	9
558	B:B:F235	G:G:L37	12.18	Yes	No	10	6	7
559	B:B:F235	G:G:Y40	4.13	Yes	Yes	10	6	6
560	B:B:F278	B:B:P236	4.33	Yes	Yes	10	7	7
561	B:B:G282	B:B:P236	4.06	No	Yes	10	9	7
562	B:B:P236	G:G:Y40	8.34	Yes	Yes	10	7	6
563	B:B:G238	B:B:N237	3.39	No	Yes	0	7	5
564	B:B:N237	B:B:N239	13.62	Yes	No	0	5	2
565	B:B:N237	G:G:D36	4.04	Yes	No	0	5	5
566	B:B:N237	G:G:Y40	6.98	Yes	Yes	10	5	6
567	B:B:N239	B:B:R256	13.26	No	No	0	2	9
568	B:B:A240	G:G:L37	4.73	No	No	10	6	7
569	B:B:F241	B:B:F253	11.79	Yes	Yes	3	6	6
570	B:B:F241	B:B:L255	6.09	Yes	No	3	6	6
571	B:B:A242	B:B:L285	3.15	No	Yes	0	4	6
572	B:B:F253	B:B:T243	6.49	Yes	Yes	3	6	8
573	B:B:G244	B:B:I273	5.29	No	No	0	5	6
574	B:B:D247	B:B:S245	4.42	Yes	No	0	9	9
575	B:B:D247	B:B:T249	5.78	Yes	Yes	0	9	6
576	B:B:R251	B:B:T249	3.88	Yes	Yes	3	8	6
577	B:B:T249	B:B:T263	3.14	Yes	No	3	6	1
578	B:B:S265	B:B:T249	3.2	No	Yes	0	2	6
579	B:B:C250	B:B:Y264	5.38	No	Yes	0	8	5
580	B:B:C250	B:B:I273	3.27	No	No	0	8	6
581	B:B:E260	B:B:R251	9.3	No	Yes	0	6	8
582	B:B:R251	B:B:T263	16.82	Yes	No	3	8	1
583	B:B:L252	B:B:L261	4.15	No	No	0	7	5
584	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
585	B:B:L252	G:G:L37	4.15	No	No	0	7	7
586	B:B:E260	B:B:F253	3.5	No	Yes	0	6	6
587	B:B:D254	B:B:R256	13.1	Yes	No	0	9	9
588	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
589	B:B:D254	B:B:L261	4.07	Yes	No	0	9	5
590	B:B:D254	G:G:A33	4.63	Yes	No	0	9	7
591	B:B:R256	G:G:D36	11.91	No	No	0	9	5
592	B:B:D258	G:G:E22	3.9	Yes	Yes	3	7	9
593	B:B:D258	G:G:R27	15.48	Yes	Yes	3	7	8
594	B:B:M262	B:B:Y264	5.99	Yes	Yes	1	4	5
595	B:B:A302	B:B:M262	4.83	No	Yes	1	2	4
596	B:B:L285	B:B:Y264	9.38	Yes	Yes	0	6	5
597	B:B:W297	B:B:Y264	15.43	Yes	Yes	1	8	5
598	B:B:A302	B:B:Y264	4	No	Yes	1	2	5
599	B:B:I269	B:B:S265	3.1	No	No	0	4	2
600	B:B:H266	B:B:N268	3.83	No	No	0	4	4
601	B:B:H266	B:B:W297	6.35	No	Yes	1	4	8
602	B:B:H266	B:B:R304	5.64	No	No	1	4	5
603	B:B:I269	B:B:N268	5.66	No	No	0	4	4
604	B:B:C271	B:B:Y289	4.03	No	Yes	1	5	7
605	B:B:C271	B:B:D290	4.67	No	Yes	1	5	6
606	B:B:C271	B:B:D291	7.78	No	No	1	5	8
607	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
608	B:B:I273	B:B:Y289	14.51	No	Yes	0	6	7
609	B:B:S275	B:B:T274	3.2	No	No	0	8	8
610	B:B:D290	B:B:T274	4.34	Yes	No	1	6	8
611	B:B:R314	B:B:T274	9.06	Yes	No	1	8	8
612	B:B:L318	B:B:S275	9.01	No	No	0	6	8
613	B:B:L318	B:B:S277	4.5	No	No	0	6	5
614	B:B:F278	B:B:G282	3.01	Yes	No	10	7	9
615	B:B:F278	B:B:L285	9.74	Yes	Yes	0	7	6
616	B:B:S279	G:G:D48	10.31	No	Yes	0	9	9
617	B:B:S279	G:G:L50	4.5	No	No	0	9	9
618	B:B:S281	G:G:D48	10.31	No	Yes	1	9	9
619	B:B:S281	G:G:L51	3	No	Yes	1	9	6
620	B:B:D298	B:B:R283	14.29	No	Yes	1	9	9
621	B:B:L300	B:B:R283	9.72	No	Yes	1	6	9
622	B:B:L284	B:B:V296	5.96	No	No	0	5	5
623	B:B:L286	B:B:V327	4.47	No	No	0	7	6
624	B:B:A287	B:B:Y289	5.34	No	Yes	0	6	7
625	B:B:G288	B:B:V315	3.68	No	Yes	0	7	7
626	B:B:D291	B:B:Y289	4.6	No	Yes	1	8	7
627	B:B:N295	B:B:Y289	16.28	Yes	Yes	1	6	7
628	B:B:W297	B:B:Y289	9.65	Yes	Yes	1	8	7
629	B:B:D290	B:B:R314	9.53	Yes	Yes	1	6	8
630	B:B:D291	B:B:N293	4.04	No	No	0	8	5
631	B:B:F292	B:B:N313	7.25	No	No	0	4	7
632	B:B:N293	B:B:V307	4.43	No	No	0	5	3
633	B:B:A309	B:B:N293	6.25	No	No	0	3	5
634	B:B:C294	B:B:L308	4.76	No	No	0	5	7
635	B:B:C294	B:B:V315	5.12	No	Yes	0	5	7
636	B:B:C294	B:B:T329	3.38	No	No	0	5	8
637	B:B:N295	B:B:W297	3.39	Yes	Yes	1	6	8
638	B:B:N295	B:B:R304	9.64	Yes	No	1	6	5
639	B:B:N295	B:B:V307	5.91	Yes	No	0	6	3
640	B:B:R304	B:B:W297	11	No	Yes	1	5	8
641	B:B:D298	B:B:K301	6.91	No	No	0	9	5
642	B:B:L300	G:G:M38	7.07	No	No	1	6	4
643	B:B:L308	B:B:W339	17.08	No	Yes	0	7	9
644	B:B:H311	B:B:V315	5.54	Yes	Yes	6	9	7
645	B:B:H311	B:B:T329	9.58	Yes	No	6	9	8
646	B:B:H311	B:B:S331	12.55	Yes	No	6	9	9
647	B:B:D333	B:B:H311	6.3	Yes	Yes	6	9	9
648	B:B:H311	B:B:K337	14.41	Yes	Yes	6	9	6
649	B:B:H311	B:B:W339	3.17	Yes	Yes	6	9	9
650	B:B:D312	B:B:D333	7.98	No	Yes	0	5	9
651	B:B:D312	R:R:K333	12.44	No	No	0	5	6
652	B:B:N313	B:B:R314	3.62	No	Yes	1	7	8
653	B:B:N313	B:B:W332	3.39	No	Yes	1	7	9
654	B:B:R314	B:B:W332	34.99	Yes	Yes	1	8	9
655	B:B:L318	B:B:V315	2.98	No	Yes	0	6	7
656	B:B:S331	B:B:V315	3.23	No	Yes	6	9	7
657	B:B:C317	B:B:S316	5.16	Yes	No	0	7	9
658	B:B:S316	B:B:W332	6.18	No	Yes	0	9	9
659	B:B:C317	B:B:G330	3.92	Yes	No	0	7	5
660	B:B:V320	B:B:V327	6.41	No	No	0	7	6
661	B:B:D323	B:B:T321	7.23	No	Yes	7	7	7
662	B:B:G324	B:B:T321	3.64	No	Yes	0	9	7
663	B:B:D323	B:B:M325	9.7	No	No	0	7	5
664	B:B:M325	G:G:P49	5.03	No	No	0	5	7
665	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
666	B:B:T329	B:B:W339	12.13	No	Yes	6	8	9
667	B:B:D333	B:B:S331	5.89	Yes	No	6	9	9
668	B:B:D333	B:B:F335	13.14	Yes	Yes	6	9	4
669	B:B:F335	B:B:K337	3.72	Yes	Yes	6	4	6
670	B:B:F335	R:R:Y57	8.25	Yes	Yes	6	4	5
671	B:B:K337	B:B:W339	9.28	Yes	Yes	6	6	9
672	G:G:L15	G:G:Q18	5.32	No	No	0	2	9
673	G:G:L19	G:G:Q18	3.99	Yes	No	0	9	9
674	G:G:E22	G:G:R27	4.65	Yes	Yes	3	9	8
675	G:G:I25	G:G:R27	3.76	No	Yes	0	2	8
676	G:G:I28	G:G:K32	8.72	No	No	0	4	5
677	G:G:K29	G:G:S31	3.06	No	No	0	4	9
678	G:G:H44	G:G:Y40	28.31	No	Yes	0	6	6
679	G:G:D48	G:G:L51	9.5	Yes	Yes	1	9	6
680	G:G:L51	G:G:T52	5.9	Yes	No	0	6	4
681	R:R:I27	R:R:T29	9.12	No	No	0	2	3
682	R:R:I27	R:R:Q30	12.35	No	Yes	0	2	4
683	R:R:Q30	R:R:T307	15.59	Yes	No	19	4	5
684	R:R:Q30	R:R:W308	5.48	Yes	No	19	4	5
685	R:R:Q30	R:R:W311	3.29	Yes	Yes	19	4	7
686	R:R:F31	R:R:I35	15.07	No	No	20	4	4
687	R:R:F31	R:R:V85	5.24	No	Yes	20	4	5
688	R:R:F31	R:R:I89	15.07	No	No	20	4	4
689	R:R:I34	R:R:V85	3.07	Yes	Yes	0	7	5
690	R:R:I34	R:R:W311	14.09	Yes	Yes	0	7	7
691	R:R:F314	R:R:I34	3.77	Yes	Yes	0	7	7
692	R:R:I35	R:R:V85	6.14	No	Yes	20	4	5
693	R:R:F40	R:R:V36	5.24	No	No	0	4	4
694	R:R:A315	R:R:I37	4.87	No	No	0	4	8
695	R:R:L81	R:R:T38	10.32	Yes	No	0	8	6
696	R:R:F40	R:R:V318	7.87	No	No	0	4	6
697	R:R:S77	R:R:V41	3.23	No	Yes	0	6	7
698	R:R:L81	R:R:V41	4.47	Yes	Yes	0	8	7
699	R:R:A317	R:R:V41	5.09	No	Yes	0	9	7
700	R:R:V318	R:R:V41	3.21	No	Yes	0	6	7
701	R:R:C42	R:R:S77	5.16	No	No	0	6	6
702	R:R:G44	R:R:L43	5.13	No	No	0	8	4
703	R:R:L43	R:R:V47	2.98	No	No	0	4	7
704	R:R:N45	R:R:T70	4.39	No	No	0	9	9
705	R:R:N45	R:R:N73	10.9	No	No	0	9	9
706	R:R:N45	R:R:P321	14.66	No	No	0	9	9
707	R:R:L46	R:R:V50	5.96	No	No	0	4	4
708	R:R:F74	R:R:L46	9.74	No	No	0	7	4
709	R:R:L335	R:R:V47	4.47	No	No	0	7	7
710	R:R:I48	R:R:T70	10.64	No	No	0	8	9
711	R:R:F67	R:R:V49	5.24	No	No	0	6	7
712	R:R:T70	R:R:V49	4.76	No	No	0	9	7
713	R:R:L71	R:R:V49	4.47	No	No	0	5	7
714	R:R:E334	R:R:T51	5.64	Yes	No	0	7	8
715	R:R:L335	R:R:T51	7.37	No	No	0	7	8
716	R:R:M338	R:R:T51	6.02	No	No	0	5	8
717	R:R:L52	R:R:L59	4.15	No	No	0	7	8
718	R:R:L52	R:R:N63	4.12	No	Yes	0	7	9
719	R:R:F67	R:R:L52	6.09	No	No	0	6	7
720	R:R:K55	R:R:Y57	14.33	No	Yes	6	6	5
721	R:R:E334	R:R:K55	24.3	Yes	No	6	7	6
722	R:R:K55	R:R:M338	5.76	No	No	0	6	5
723	R:R:L59	R:R:S56	3	No	No	0	8	7
724	R:R:L58	R:R:Y57	8.21	No	Yes	6	8	5
725	R:R:E334	R:R:Y57	5.61	Yes	Yes	6	7	5
726	R:R:L58	R:R:T330	5.9	No	No	0	8	7
727	R:R:E334	R:R:L58	11.93	Yes	No	6	7	8
728	R:R:K64	R:R:L59	5.64	No	No	0	5	8
729	R:R:N63	R:R:T60	4.39	Yes	No	0	9	7
730	R:R:G141	R:R:L61	5.13	No	No	0	4	5
731	R:R:A144	R:R:L61	6.3	No	No	0	7	5
732	R:R:N328	R:R:N63	4.09	No	Yes	25	9	9
733	R:R:N63	R:R:V331	7.39	Yes	No	25	9	8
734	R:R:A144	R:R:K64	3.21	No	No	0	7	5
735	R:R:K64	R:R:V145	3.04	No	No	0	5	4
736	R:R:F65	R:R:V120	7.87	No	No	0	8	6
737	R:R:F65	R:R:L148	4.87	No	No	0	8	7
738	R:R:I121	R:R:V66	3.07	Yes	No	0	9	8
739	R:R:L148	R:R:S68	7.51	No	No	0	7	9
740	R:R:S68	R:R:W152	4.94	No	Yes	0	9	9
741	R:R:L69	R:R:T117	10.32	No	No	0	9	8
742	R:R:H320	R:R:L69	3.86	Yes	No	0	9	9
743	R:R:I110	R:R:S72	4.64	No	No	0	7	8
744	R:R:S114	R:R:S72	3.26	No	No	0	9	8
745	R:R:S72	R:R:W152	4.94	No	Yes	0	8	9
746	R:R:N73	R:R:S114	10.43	No	No	0	9	9
747	R:R:A317	R:R:N73	4.69	No	No	0	9	9
748	R:R:F74	R:R:V78	5.24	No	No	0	7	4
749	R:R:L76	R:R:V80	7.45	No	No	0	7	7
750	R:R:I110	R:R:L76	12.85	No	No	0	7	7
751	R:R:S77	R:R:V78	3.23	No	No	0	6	4
752	R:R:L79	R:R:V78	2.98	No	No	0	5	4
753	R:R:L106	R:R:L79	4.15	No	No	0	5	5
754	R:R:F314	R:R:L81	12.18	Yes	Yes	0	7	8
755	R:R:F83	R:R:F95	11.79	No	Yes	11	5	6
756	R:R:F83	R:R:W99	16.04	No	Yes	11	5	5
757	R:R:M177	R:R:V84	10.65	Yes	No	4	3	7
758	R:R:F314	R:R:V84	3.93	Yes	No	4	7	7
759	R:R:I89	R:R:V85	3.07	No	Yes	20	4	5
760	R:R:F95	R:R:T86	9.08	Yes	No	0	6	5
761	R:R:S87	R:R:W93	7.41	No	Yes	11	5	8
762	R:R:F171	R:R:S87	6.61	No	No	11	3	5
763	R:R:S88	R:R:W176	9.88	No	Yes	0	5	3
764	R:R:S88	R:R:W311	3.71	No	Yes	0	5	7
765	R:R:I94	R:R:R90	6.26	No	No	0	3	4
766	R:R:R91	R:R:W176	4	No	Yes	0	3	3
767	R:R:F95	R:R:W93	19.04	Yes	Yes	11	6	8
768	R:R:C100	R:R:W93	9.14	No	Yes	11	9	8
769	R:R:F171	R:R:W93	6.01	No	Yes	11	3	8
770	R:R:C178	R:R:W93	9.14	No	Yes	11	9	8
771	R:R:F95	R:R:I94	11.3	Yes	No	0	6	3
772	R:R:F95	R:R:W99	6.01	Yes	Yes	11	6	5
773	R:R:F102	R:R:V98	3.93	No	No	0	4	3
774	R:R:F102	R:R:W99	7.02	No	Yes	0	4	5
775	R:R:S103	R:R:W99	9.88	No	Yes	0	5	5
776	R:R:C100	R:R:C178	7.28	No	No	11	9	9
777	R:R:N101	R:R:V169	4.43	No	No	0	6	4
778	R:R:A104	R:R:V169	5.09	No	No	0	5	4
779	R:R:C159	R:R:L105	3.17	No	No	0	8	7
780	R:R:L105	R:R:P162	3.28	No	No	0	7	7
781	R:R:L105	R:R:L163	4.15	No	No	0	7	6
782	R:R:S111	R:R:Y107	6.36	No	Yes	0	6	8
783	R:R:M177	R:R:Y107	5.99	Yes	Yes	4	3	8
784	R:R:V179	R:R:Y107	5.05	Yes	Yes	4	3	8
785	R:R:Y107	R:R:Y286	5.96	Yes	Yes	4	8	7
786	R:R:F314	R:R:Y107	7.22	Yes	Yes	4	7	8
787	R:R:C159	R:R:L108	3.17	No	Yes	0	8	6
788	R:R:L108	R:R:V179	2.98	Yes	Yes	0	6	3
789	R:R:L108	R:R:Y188	3.52	Yes	Yes	0	6	8
790	R:R:L108	R:R:W192	5.69	Yes	Yes	0	6	6
791	R:R:L109	R:R:W152	6.83	No	Yes	0	6	9
792	R:R:C159	R:R:L109	4.76	No	No	0	8	6
793	R:R:S111	R:R:W283	4.94	No	Yes	0	6	8
794	R:R:S112	R:R:S155	3.26	No	No	0	7	8
795	R:R:S112	R:R:W192	3.71	No	Yes	4	7	6
796	R:R:C196	R:R:S112	6.89	No	No	4	7	7
797	R:R:A113	R:R:W152	7.78	No	Yes	0	8	9
798	R:R:A113	R:R:S155	3.42	No	No	0	8	8
799	R:R:M115	R:R:P200	3.35	No	No	0	8	9
800	R:R:F279	R:R:M115	8.71	Yes	No	8	9	8
801	R:R:M115	R:R:W283	22.1	No	Yes	8	8	8
802	R:R:H154	R:R:L116	10.29	No	No	0	4	6
803	R:R:L116	R:R:P200	6.57	No	No	0	6	9
804	R:R:I121	R:R:T117	3.04	Yes	No	0	9	8
805	R:R:I151	R:R:T117	6.08	No	No	0	6	8
806	R:R:L118	R:R:M204	4.24	Yes	No	8	9	8
807	R:R:F279	R:R:L118	4.87	Yes	Yes	8	9	9
808	R:R:H320	R:R:L118	14.14	Yes	Yes	8	9	9
809	R:R:L118	R:R:Y324	5.86	Yes	Yes	8	9	9
810	R:R:G119	R:R:V203	3.68	No	No	0	6	6
811	R:R:I151	R:R:V120	7.68	No	No	0	6	6
812	R:R:I121	R:R:R125	5.01	Yes	Yes	8	9	9
813	R:R:I121	R:R:Y324	9.67	Yes	Yes	8	9	9
814	R:R:A122	R:R:M204	3.22	No	No	0	9	8
815	R:R:A122	R:R:Y208	4	No	Yes	0	9	9
816	R:R:I123	R:R:V203	3.07	No	No	0	6	6
817	R:R:D124	R:R:Y135	9.2	No	Yes	0	9	8
818	R:R:R125	R:R:Y208	10.29	Yes	Yes	8	9	9
819	R:R:R125	R:R:Y324	6.17	Yes	Yes	8	9	9
820	R:R:Y126	R:R:Y127	6.95	Yes	Yes	15	9	5
821	R:R:L130	R:R:Y126	7.03	Yes	Yes	15	6	9
822	R:R:Y126	R:R:Y131	5.96	Yes	Yes	15	9	6
823	R:R:C207	R:R:Y126	4.03	No	Yes	0	6	9
824	R:R:Y127	R:R:Y131	3.97	Yes	Yes	15	5	6
825	R:R:K138	R:R:Y127	4.78	No	Yes	15	5	5
826	R:R:I139	R:R:Y127	8.46	No	Yes	0	6	5
827	R:R:A128	R:R:Y135	8.01	No	Yes	0	8	8
828	R:R:L130	R:R:V129	2.98	Yes	No	0	6	9
829	R:R:I211	R:R:V129	6.14	No	No	0	9	9
830	R:R:L130	R:R:Y131	5.86	Yes	Yes	15	6	6
831	R:R:L130	R:R:V214	2.98	Yes	No	0	6	6
832	R:R:K138	R:R:Y131	7.17	No	Yes	15	5	6
833	R:R:M137	R:R:V134	3.04	No	No	0	5	5
834	R:R:K138	R:R:V134	7.59	No	No	0	5	5
835	R:R:P136	R:R:Y135	4.17	Yes	Yes	0	5	8
836	R:R:I139	R:R:Y135	4.84	No	Yes	0	6	8
837	R:R:I139	R:R:R143	3.76	No	No	0	6	6
838	R:R:G141	R:R:T140	3.64	No	No	0	4	8
839	R:R:L153	R:R:V149	2.98	No	No	0	3	3
840	R:R:H154	R:R:Y150	6.53	No	No	0	4	2
841	R:R:I151	R:R:W152	3.52	No	Yes	0	6	9
842	R:R:H154	R:R:W195	32.8	No	Yes	0	4	4
843	R:R:I157	R:R:W195	4.7	No	Yes	0	4	4
844	R:R:F191	R:R:G158	3.01	No	No	0	4	6
845	R:R:L160	R:R:P161	4.93	No	Yes	0	5	6
846	R:R:P161	R:R:P162	5.84	Yes	No	4	6	7
847	R:R:P161	R:R:W166	9.46	Yes	No	0	6	6
848	R:R:P161	R:R:Y188	5.56	Yes	Yes	4	6	8
849	R:R:P162	R:R:Y188	6.95	No	Yes	4	7	8
850	R:R:E185	R:R:S167	5.75	No	No	0	5	5
851	R:R:C178	R:R:V169	3.42	No	No	0	9	4
852	R:R:A181	R:R:E170	4.53	No	No	26	4	2
853	R:R:E170	R:R:R184	8.14	No	Yes	26	2	3
854	R:R:F171	R:R:W176	5.01	No	Yes	0	3	3
855	R:R:D172	R:R:K175	15.21	No	Yes	0	3	2
856	R:R:D172	R:R:H183	5.04	No	No	0	3	6
857	R:R:D172	R:R:K298	5.53	No	Yes	0	3	1
858	R:R:F174	R:R:K298	3.72	No	Yes	4	2	1
859	R:R:F174	R:R:P303	18.78	No	No	0	2	3
860	R:R:E306	R:R:F174	8.16	Yes	No	4	5	2
861	R:R:K175	R:R:W182	6.96	Yes	Yes	4	2	5
862	R:R:K175	R:R:Y286	7.17	Yes	Yes	4	2	7
863	R:R:E293	R:R:K175	8.1	Yes	Yes	4	4	2
864	R:R:E306	R:R:K175	12.15	Yes	Yes	4	5	2
865	R:R:K175	R:R:T310	6.01	Yes	No	4	2	6
866	R:R:T307	R:R:W176	4.85	No	Yes	0	5	3
867	R:R:M177	R:R:V179	4.56	Yes	Yes	4	3	3
868	R:R:F314	R:R:M177	3.73	Yes	Yes	4	7	3
869	R:R:V179	R:R:W182	7.36	Yes	Yes	4	3	5
870	R:R:A181	R:R:R184	4.15	No	Yes	26	4	3
871	R:R:W182	R:R:Y188	3.86	Yes	Yes	4	5	8
872	R:R:T189	R:R:W182	12.13	No	Yes	4	6	5
873	R:R:W182	R:R:W192	6.56	Yes	Yes	4	5	6
874	R:R:W182	R:R:Y286	6.75	Yes	Yes	4	5	7
875	R:R:I290	R:R:W182	10.57	Yes	Yes	4	7	5
876	R:R:H183	R:R:R184	5.64	No	Yes	0	6	3
877	R:R:E185	R:R:G187	4.91	No	No	0	5	4
878	R:R:F191	R:R:Y188	4.13	No	Yes	0	4	8
879	R:R:I290	R:R:T189	4.56	Yes	No	4	7	6
880	R:R:A294	R:R:T189	5.03	No	No	0	6	6
881	R:R:F191	R:R:W195	8.02	No	Yes	0	4	4
882	R:R:C196	R:R:W192	3.92	No	Yes	4	7	6
883	R:R:W192	R:R:Y286	3.86	Yes	Yes	4	6	7
884	R:R:M287	R:R:W192	3.49	Yes	Yes	0	7	6
885	R:R:M287	R:R:Q193	8.16	Yes	No	0	7	6
886	R:R:I290	R:R:Q193	6.86	Yes	No	0	7	6
887	R:R:A291	R:R:Q193	4.55	No	No	0	5	6
888	R:R:C196	R:R:W195	3.92	No	Yes	0	7	4
889	R:R:A197	R:R:M287	4.83	No	Yes	0	8	7
890	R:R:L198	R:R:L202	5.54	No	No	0	5	4
891	R:R:F199	R:R:P200	4.33	No	No	0	5	9
892	R:R:F201	R:R:L205	7.31	Yes	No	0	6	5
893	R:R:F201	R:R:L276	4.87	Yes	No	0	6	8
894	R:R:F201	R:R:F279	10.72	Yes	Yes	0	6	9
895	R:R:F201	R:R:M280	6.22	Yes	No	0	6	5
896	R:R:F279	R:R:M204	4.98	Yes	No	8	9	8
897	R:R:F210	R:R:V206	3.93	No	No	0	6	3
898	R:R:I272	R:R:Y208	7.25	No	Yes	0	8	9
899	R:R:V275	R:R:Y208	5.05	No	Yes	0	8	9
900	R:R:L276	R:R:Y208	3.52	No	Yes	0	8	9
901	R:R:Y208	R:R:Y324	4.96	Yes	Yes	8	9	9
902	R:R:F210	R:R:R213	6.41	No	No	0	6	4
903	R:R:F212	R:R:R216	11.76	Yes	No	27	6	6
904	R:R:F212	R:R:L269	7.31	Yes	No	27	6	7
905	R:R:L269	R:R:R216	6.07	No	No	27	7	6
906	R:R:T271	R:R:W327	13.34	No	No	0	9	7
907	R:R:V274	R:R:W327	4.9	No	No	0	7	7
908	R:R:A278	R:R:C319	3.61	No	No	0	6	6
909	R:R:F279	R:R:W283	7.02	Yes	Yes	8	9	8
910	R:R:T282	R:R:W283	4.85	No	Yes	8	8	8
911	R:R:S316	R:R:T282	4.8	No	No	8	9	8
912	R:R:C319	R:R:T282	3.38	No	No	0	6	8
913	R:R:M287	R:R:W283	4.65	Yes	Yes	0	7	8
914	R:R:S313	R:R:W283	8.65	No	Yes	0	7	8
915	R:R:S316	R:R:W283	14.83	No	Yes	8	9	8
916	R:R:H320	R:R:W283	4.23	Yes	Yes	8	9	8
917	R:R:G284	R:R:P285	4.06	No	No	0	6	9
918	R:R:G284	R:R:M287	3.49	No	Yes	0	6	7
919	R:R:L312	R:R:P285	3.28	No	No	0	7	9
920	R:R:I290	R:R:Y286	7.25	Yes	Yes	4	7	7
921	R:R:T310	R:R:Y286	4.99	No	Yes	4	6	7
922	R:R:S313	R:R:Y286	12.72	No	Yes	0	7	7
923	R:R:V289	R:R:V301	3.21	No	Yes	0	5	4
924	R:R:A309	R:R:V289	3.39	No	No	0	6	5
925	R:R:S292	R:R:S300	3.26	No	No	4	5	3
926	R:R:E293	R:R:K298	8.1	Yes	Yes	4	4	1
927	R:R:E293	R:R:V301	4.28	Yes	Yes	4	4	4
928	R:R:E293	R:R:E306	12.69	Yes	Yes	4	4	5
929	R:R:L295	R:R:W296	7.97	No	No	0	5	3
930	R:R:E306	R:R:K298	9.45	Yes	Yes	4	5	1
931	R:R:L305	R:R:V301	2.98	No	Yes	0	4	4
932	R:R:E306	R:R:V301	5.7	Yes	Yes	4	5	4
933	R:R:P303	R:R:S302	3.56	No	No	0	3	4
934	R:R:L305	R:R:S302	6.01	No	No	0	4	4
935	R:R:T307	R:R:W311	6.06	No	Yes	19	5	7
936	R:R:W308	R:R:W311	6.56	No	Yes	19	5	7
937	R:R:H320	R:R:S316	8.37	Yes	No	8	9	9
938	R:R:I323	R:R:Y324	6.04	No	Yes	0	8	9
939	R:R:N328	R:R:T330	4.39	No	No	0	9	7
940	R:R:N328	R:R:V331	7.39	No	No	25	9	8
941	R:R:K329	R:R:R332	7.43	No	No	0	6	9
942	R:R:L336	R:R:R332	3.64	No	No	0	5	9
943	R:R:N101	R:R:V97	2.96	No	No	0	6	3
944	A:A:L393	R:R:T271	2.95	No	No	0	8	9
945	B:B:L30	B:B:T34	2.95	No	Yes	1	5	5
946	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
947	R:R:I28	R:R:I32	2.94	No	No	0	5	3
948	R:R:I34	R:R:I37	2.94	Yes	No	0	7	8
949	R:R:D124	R:R:S62	2.94	No	No	0	9	8
950	R:R:N142	R:R:T140	2.92	No	No	0	5	8
951	R:R:Q30	R:R:S304	2.89	Yes	No	0	4	1
952	B:B:Q259	G:G:V30	2.87	Yes	No	0	6	8
953	A:A:E370	A:A:T369	2.82	No	No	0	4	9
954	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
955	R:R:G96	R:R:W93	2.81	No	Yes	0	7	8
956	A:A:K293	A:A:N292	2.8	No	Yes	0	9	9
957	B:B:K301	B:B:N35	2.8	No	No	0	5	1
958	B:B:K127	B:B:N110	2.8	No	No	0	4	4
959	B:B:D118	B:B:I120	2.8	No	No	0	9	6
960	B:B:F235	G:G:C41	2.79	Yes	No	0	6	7
961	R:R:C266	R:R:R216	2.79	No	No	0	5	6
962	A:A:A337	A:A:F315	2.77	No	Yes	0	8	6
963	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
964	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
965	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
966	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
967	R:R:A147	R:R:F65	2.77	No	No	0	6	8
968	R:R:L109	R:R:L156	2.77	No	No	0	6	4
969	R:R:A268	R:R:F212	2.77	No	Yes	0	8	6
970	R:R:L322	R:R:L326	2.77	No	No	0	6	6
971	A:A:K216	A:A:Q213	2.71	No	No	0	4	3
972	B:B:D83	B:B:L69	2.71	Yes	No	0	8	5
973	R:R:A180	R:R:Y188	2.67	No	Yes	0	6	8
974	R:R:R184	R:R:S168	2.64	Yes	No	0	3	3
975	R:R:F199	R:R:V203	2.62	No	No	0	5	6
976	B:B:D20	B:B:Q17	2.61	No	No	0	2	4
977	B:B:A326	B:B:W63	2.59	No	Yes	0	7	7
978	R:R:A33	R:R:W308	2.59	No	No	0	4	5
979	A:A:E327	A:A:E330	2.54	No	Yes	0	4	3
980	R:R:F40	R:R:I39	2.51	No	No	0	4	5
981	R:R:S292	R:R:W296	2.47	No	No	4	5	3
982	R:R:S300	R:R:W296	2.47	No	No	4	3	3
983	B:B:L284	B:B:R283	2.43	No	Yes	0	5	9
984	B:B:R283	G:G:L51	2.43	Yes	Yes	1	9	6
985	A:A:E314	A:A:F312	2.33	Yes	Yes	18	6	8
986	A:A:E314	A:A:F340	2.33	Yes	Yes	18	6	7
987	R:R:E185	R:R:Y188	2.24	No	Yes	0	5	8
988	R:R:E173	R:R:W176	2.18	No	Yes	0	1	3
989	B:B:R46	B:B:R48	2.13	No	No	0	5	7
990	A:A:G225	A:A:G226	2.11	No	No	0	9	9
991	R:R:F67	R:R:Y53	2.06	No	No	0	6	4
992	A:A:A303	A:A:G304	1.95	No	No	0	5	5
993	A:A:A39	R:R:P136	1.87	No	Yes	0	5	5
994	B:B:A106	B:B:P107	1.87	No	No	0	6	6
995	R:R:A294	R:R:P186	1.87	No	No	0	6	4
996	A:A:G47	A:A:S51	1.86	No	No	0	9	9
997	B:B:G77	B:B:S98	1.86	No	No	0	8	8
998	B:B:G144	B:B:S161	1.86	No	Yes	0	8	9
999	B:B:G306	B:B:V296	1.84	No	No	0	4	5
1000	B:B:G174	B:B:T173	1.82	No	No	0	4	5
1001	B:B:G182	B:B:T181	1.82	No	No	0	6	2
1002	R:R:A215	R:R:A268	1.79	No	No	0	8	8
1003	R:R:G325	R:R:I48	1.76	No	No	0	7	8
1004	A:A:P326	A:A:T325	1.75	No	No	0	1	2
1005	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1006	R:R:G277	R:R:M280	1.75	No	No	0	6	5
1007	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
1008	A:A:A351	A:A:S352	1.71	No	No	0	4	5
1009	R:R:G337	R:R:L336	1.71	No	No	0	3	5
1010	A:A:G52	A:A:N292	1.7	No	Yes	0	9	9
1011	A:A:A298	A:A:V334	1.7	No	Yes	0	4	4
1012	B:B:G131	B:B:N132	1.7	No	No	0	4	3
1013	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
1014	B:B:E260	B:B:G224	1.64	No	No	0	6	6
1015	R:R:L81	R:R:P82	1.64	Yes	No	0	8	8
1016	A:A:I26	B:B:A92	1.62	No	No	0	9	6
1017	B:B:I33	G:G:A34	1.62	No	No	0	3	6
1018	B:B:A92	B:B:I80	1.62	No	No	0	6	8
1019	B:B:A140	B:B:I120	1.62	No	No	0	5	6
1020	B:B:A248	B:B:I269	1.62	No	No	0	5	4
1021	G:G:A10	G:G:I9	1.62	No	No	0	2	2
1022	R:R:S292	R:R:V301	1.62	No	Yes	4	5	4
1023	A:A:S54	A:A:T55	1.6	No	No	0	9	9
1024	A:A:S349	A:A:T350	1.6	Yes	No	0	7	4
1025	R:R:V145	R:R:V149	1.6	No	No	0	4	3
1026	A:A:Q35	R:R:P136	1.58	No	Yes	0	3	5
1027	B:B:A11	G:G:L19	1.58	No	Yes	0	5	9
1028	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
1029	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
1030	A:A:C365	A:A:D368	1.56	No	Yes	0	8	9
1031	G:G:A39	G:G:D36	1.54	No	No	0	3	5
1032	A:A:I285	A:A:T284	1.52	No	No	0	7	4
1033	B:B:I33	B:B:T34	1.52	No	Yes	0	3	5
1034	G:G:K20	G:G:V16	1.52	No	No	0	6	7
1035	R:R:I28	R:R:T29	1.52	No	No	0	5	3
1036	A:A:A22	A:A:E21	1.51	No	No	0	4	2
1037	A:A:A298	A:A:E299	1.51	No	No	0	4	6
1038	A:A:A316	A:A:E309	1.51	No	No	0	2	4
1039	R:R:F212	R:R:G209	1.51	Yes	No	0	6	2
1040	A:A:K58	A:A:T55	1.5	No	No	0	9	9
1041	R:R:K267	R:R:T271	1.5	No	No	0	8	9
1042	R:R:L205	R:R:V206	1.49	No	No	0	5	3
1043	R:R:L322	R:R:V318	1.49	No	No	0	6	6
1044	A:A:N218	A:A:T40	1.46	No	No	0	4	7
1045	B:B:D27	G:G:V30	1.46	No	No	0	8	8
1046	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1047	G:G:A43	G:G:H44	1.46	No	No	0	4	6
1048	G:G:K29	G:G:K32	1.44	No	No	0	4	5
1049	B:B:E10	G:G:V16	1.43	No	No	0	8	7
1050	R:R:I194	R:R:L198	1.43	No	No	0	3	5
1051	A:A:E16	B:B:T86	1.41	No	Yes	0	4	6
1052	G:G:K20	G:G:N24	1.4	No	No	0	6	1
1053	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
1054	A:A:D33	A:A:K32	1.38	No	No	0	5	4
1055	A:A:A48	A:A:R265	1.38	No	Yes	0	8	9
1056	R:R:L75	R:R:L79	1.38	No	No	0	7	5
1057	A:A:E21	A:A:K17	1.35	No	No	0	2	4
1058	A:A:E392	R:R:K267	1.35	No	No	0	6	8
1059	B:B:K280	G:G:E47	1.35	No	No	0	1	3
1060	G:G:E17	G:G:K14	1.35	No	No	0	6	4
1061	A:A:E27	A:A:Q31	1.27	No	No	0	6	4
1062	A:A:F208	A:A:I207	1.26	No	No	0	5	9
1063	R:R:F201	R:R:L198	1.22	Yes	No	0	6	5
1064	A:A:D49	A:A:R265	1.19	No	Yes	0	8	9
1065	A:A:D229	A:A:R231	1.19	No	Yes	0	8	9
1066	B:B:D5	B:B:R8	1.19	No	No	0	1	3
1067	A:A:E209	A:A:F208	1.17	No	No	0	9	5
1068	B:B:E130	B:B:R134	1.16	No	No	0	3	3
1069	G:G:E17	G:G:R13	1.16	No	No	0	6	6
1070	R:R:E92	R:R:R90	1.16	No	No	0	4	4
1071	A:A:D310	A:A:Y311	1.15	No	Yes	0	3	6
1072	B:B:R48	B:B:R49	1.07	No	No	0	7	7
1073	R:R:F164	R:R:W166	1	No	No	0	5	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Y37	7.55	4	16	4
2	A:A:L44	9.435	4	1	9
3	A:A:L46	4.78	4	1	8
4	A:A:K53	6.6925	4	21	9
5	A:A:F219	6.792	5	0	8
6	A:A:F222	7.2675	4	1	7
7	A:A:Q227	4.436	5	2	9
8	A:A:R231	4.475	4	0	9
9	A:A:K233	7.25333	6	2	9
10	A:A:F238	11.3325	4	1	9
11	A:A:D240	6.5225	4	1	6
12	A:A:I244	4.924	5	1	8
13	A:A:F246	5.755	4	1	9
14	A:A:V247	3.6175	4	0	7
15	A:A:Y253	8.59	4	0	8
16	A:A:R265	4.745	4	0	9
17	A:A:L270	5.516	5	0	6
18	A:A:F273	5.62571	7	1	9
19	A:A:W277	10.222	5	1	6
20	A:A:W281	14.425	4	1	5
21	A:A:L282	7.015	4	0	9
22	A:A:L289	5.746	5	1	9
23	A:A:F290	5.818	5	17	9
24	A:A:N292	4.06	4	0	9
25	A:A:V301	6.49	4	0	7
26	A:A:Y311	5.5125	4	0	6
27	A:A:F312	6.08	4	18	8
28	A:A:E314	4.0025	4	18	6
29	A:A:F315	13.726	5	0	6
30	A:A:E330	7.96	4	1	3
31	A:A:D331	6.7675	4	1	4
32	A:A:V334	4.48833	6	1	4
33	A:A:K338	8.6275	4	1	5
34	A:A:Y339	8.6075	4	1	3
35	A:A:F340	10.418	5	18	7
36	A:A:R342	7.355	4	1	4
37	A:A:F345	7.39	4	1	8
38	A:A:S349	4.48	4	1	7
39	A:A:C359	4.296	5	1	5
40	A:A:Y360	5.666	5	9	8
41	A:A:F363	9.306	5	1	5
42	A:A:T364	8.0925	4	17	9
43	A:A:D368	7.5475	4	17	9
44	A:A:N371	7.218	5	17	9
45	A:A:R373	4.805	4	14	5
46	A:A:F376	7.035	6	14	8
47	A:A:I383	4.5925	4	9	8
48	A:A:H387	4.755	4	9	8
49	A:A:L388	4.675	4	23	8
50	A:A:L394	4.265	4	23	8
51	B:B:I18	8.6725	4	3	7
52	B:B:T34	4.8175	4	1	5
53	B:B:L51	7.028	5	7	9
54	B:B:H54	8.7	6	7	9
55	B:B:K57	12.652	5	1	9
56	B:B:Y59	9.53	4	1	8
57	B:B:M61	4.67	4	7	6
58	B:B:W63	6.79667	6	7	7
59	B:B:Q75	9.336	5	1	9
60	B:B:D76	8.208	5	16	9
61	B:B:L79	4.224	5	12	7
62	B:B:W82	10.4167	6	7	9
63	B:B:D83	7.152	5	13	8
64	B:B:T86	7.56	4	13	6
65	B:B:K89	8.228	5	0	9
66	B:B:L95	5.2075	4	12	8
67	B:B:W99	11.472	5	1	9
68	B:B:Y105	5.32667	6	12	6
69	B:B:Y111	6.378	5	24	4
70	B:B:V112	4.13	4	12	8
71	B:B:C121	4.59	4	2	8
72	B:B:I123	4.3925	4	0	6
73	B:B:Y124	5.418	5	0	6
74	B:B:L126	4.85	4	12	5
75	B:B:H142	6.49857	7	2	9
76	B:B:R145	6.28833	6	2	8
77	B:B:L146	3.904	5	2	7
78	B:B:C149	4.27	4	2	8
79	B:B:F151	4.982	5	0	9
80	B:B:L152	4.502	5	5	3
81	B:B:Q156	5.27	4	5	5
82	B:B:I157	5.625	4	2	7
83	B:B:V158	4.245	4	5	5
84	B:B:T159	5.60167	6	2	9
85	B:B:S161	6.7	4	2	9
86	B:B:D163	8.1525	4	2	9
87	B:B:L168	4.96	4	5	6
88	B:B:W169	9.18833	6	2	8
89	B:B:D170	7.0675	4	5	9
90	B:B:Q176	6.7725	4	2	4
91	B:B:F180	9.006	5	5	7
92	B:B:H183	8.33833	6	5	9
93	B:B:D186	6.002	5	2	9
94	B:B:L192	4.012	5	5	5
95	B:B:R197	9.1325	4	3	5
96	B:B:F199	7.12	5	5	9
97	B:B:V200	9.48	4	3	6
98	B:B:S201	4.6075	4	5	9
99	B:B:D205	7.53	5	5	9
100	B:B:K209	11.198	5	5	6
101	B:B:L210	6.838	5	3	5
102	B:B:W211	9.97	6	5	8
103	B:B:D212	8.372	5	3	9
104	B:B:Q220	6.666	5	3	7
105	B:B:F222	8.8975	4	3	8
106	B:B:H225	9.152	5	3	9
107	B:B:D228	10.675	4	2	9
108	B:B:I229	6.2225	4	3	7
109	B:B:I232	5.65	4	3	8
110	B:B:F234	7.05	4	0	5
111	B:B:F235	7.3325	8	10	6
112	B:B:P236	7.0725	4	10	7
113	B:B:N237	7.54	5	10	5
114	B:B:F241	9.09667	6	3	6
115	B:B:T243	6.2975	4	3	8
116	B:B:D247	7.27	4	0	9
117	B:B:T249	4	4	3	6
118	B:B:R251	10.04	4	3	8
119	B:B:F253	8.125	4	3	6
120	B:B:D254	6.6075	4	0	9
121	B:B:D258	7.9975	4	3	7
122	B:B:Q259	5.045	4	0	6
123	B:B:M262	6.005	4	1	4
124	B:B:Y264	7.28333	6	1	5
125	B:B:F278	6.184	5	10	7
126	B:B:R283	6.52833	6	1	9
127	B:B:L285	5.9625	4	0	6
128	B:B:Y289	9.06833	6	1	7
129	B:B:D290	6.388	5	1	6
130	B:B:N295	8.805	4	1	6
131	B:B:W297	9.164	5	1	8
132	B:B:H311	8.59167	6	6	9
133	B:B:R314	14.438	5	1	8
134	B:B:V315	4.11	5	6	7
135	B:B:C317	3.8975	4	0	7
136	B:B:T321	7.7475	4	7	7
137	B:B:W332	14.7967	6	1	9
138	B:B:D333	8.3275	4	6	9
139	B:B:F335	8.415	4	6	4
140	B:B:K337	10.586	5	6	6
141	B:B:W339	8.26429	7	6	9
142	G:G:L19	4.545	4	0	9
143	G:G:E22	7.4	4	3	9
144	G:G:R27	7.112	5	3	8
145	G:G:Y40	11.94	4	10	6
146	G:G:D48	8.2225	4	1	9
147	G:G:L51	4.482	5	1	6
148	R:R:Q30	7.92	5	19	4
149	R:R:I34	5.9675	4	0	7
150	R:R:V41	4	4	0	7
151	R:R:Y57	9.544	5	6	5
152	R:R:N63	4.9975	4	25	9
153	R:R:L81	7.1525	4	0	8
154	R:R:V85	4.38	4	20	5
155	R:R:W93	8.925	6	11	8
156	R:R:F95	11.444	5	11	6
157	R:R:W99	9.7375	4	11	5
158	R:R:Y107	6.116	5	4	8
159	R:R:L108	3.84	4	0	6
160	R:R:L118	7.2775	4	8	9
161	R:R:I121	5.1975	4	8	9
162	R:R:R125	9.4825	4	8	9
163	R:R:Y126	5.9925	4	15	9
164	R:R:Y127	6.04	4	15	5
165	R:R:L130	4.7125	4	15	6
166	R:R:Y131	5.74	4	15	6
167	R:R:P132	4.27	4	9	9
168	R:R:Y135	6.555	4	0	8
169	R:R:P136	5.5075	4	0	5
170	R:R:W152	5.602	5	0	9
171	R:R:P161	6.4475	4	4	6
172	R:R:K175	9.26667	6	4	2
173	R:R:W176	5.184	5	0	3
174	R:R:M177	6.2325	4	4	3
175	R:R:V179	4.9875	4	4	3
176	R:R:W182	7.74143	7	4	5
177	R:R:R184	5.1425	4	26	3
178	R:R:Y188	4.13286	7	4	8
179	R:R:W192	4.53833	6	4	6
180	R:R:W195	12.36	4	0	4
181	R:R:F201	6.068	5	0	6
182	R:R:Y208	5.845	6	8	9
183	R:R:F212	5.8375	4	27	6
184	R:R:F279	7.26	5	8	9
185	R:R:W283	8.90875	8	8	8
186	R:R:Y286	6.95714	7	4	7
187	R:R:M287	4.924	5	0	7
188	R:R:I290	7.31	4	4	7
189	R:R:E293	8.2925	4	4	4
190	R:R:K298	6.7	4	4	1
191	R:R:V301	3.558	5	4	4
192	R:R:E306	9.63	5	4	5
193	R:R:W311	6.742	5	19	7
194	R:R:F314	6.166	5	4	7
195	R:R:H320	7.65	4	8	9
196	R:R:Y324	6.54	5	8	9
197	R:R:E334	11.87	4	6	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:M61	B:B:W63	11.084	6.98	Yes	Yes	7	6	7
2	B:B:C317	B:B:M61	11.5171	3.24	Yes	Yes	0	7	6
3	B:B:C317	B:B:S316	14.6112	5.16	Yes	No	0	7	9
4	B:B:S316	B:B:W332	14.7522	6.18	No	Yes	0	9	9
5	B:B:R314	B:B:W332	48.8402	34.99	Yes	Yes	1	8	9
6	B:B:R314	B:B:T274	61.933	9.06	Yes	No	1	8	8
7	B:B:S275	B:B:T274	99.9052	3.2	No	No	0	8	8
8	B:B:L318	B:B:S275	99.9369	9.01	No	No	0	6	8
9	B:B:L318	B:B:V315	100	2.98	No	Yes	0	6	7
10	B:B:H311	B:B:V315	66.7473	5.54	Yes	Yes	6	9	7
11	B:B:D333	B:B:H311	33.2129	6.3	Yes	Yes	6	9	9
12	B:B:D333	B:B:F335	66.1205	13.14	Yes	Yes	6	9	4
13	B:B:F335	R:R:Y57	99.202	8.25	Yes	Yes	6	4	5
14	R:R:L58	R:R:Y57	97.8716	8.21	No	Yes	6	8	5
15	R:R:L58	R:R:T330	97.9833	5.9	No	No	0	8	7
16	R:R:N328	R:R:T330	97.8439	4.39	No	No	0	9	7
17	R:R:N328	R:R:N63	97.5371	4.09	No	Yes	25	9	9
18	R:R:L52	R:R:N63	97.2853	4.12	No	Yes	0	7	9
19	R:R:F67	R:R:L52	95.6003	6.09	No	No	0	6	7
20	R:R:F67	R:R:V49	95.3181	5.24	No	No	0	6	7
21	R:R:T70	R:R:V49	95.0356	4.76	No	No	0	9	7
22	R:R:N45	R:R:T70	94.6111	4.39	No	No	0	9	9
23	R:R:N45	R:R:N73	94.3276	10.9	No	No	0	9	9
24	R:R:N73	R:R:S114	64.1377	10.43	No	No	0	9	9
25	R:R:S114	R:R:S72	63.9953	3.26	No	No	0	9	8
26	R:R:S72	R:R:W152	63.4333	4.94	No	Yes	0	8	9
27	R:R:I151	R:R:W152	55.7654	3.52	No	Yes	0	6	9
28	R:R:I151	R:R:T117	55.1259	6.08	No	No	0	6	8
29	R:R:I121	R:R:T117	54.1093	3.04	Yes	No	0	9	8
30	R:R:I121	R:R:R125	52.2432	5.01	Yes	Yes	8	9	9
31	A:A:Y391	R:R:R125	57.2964	16.46	No	Yes	0	4	9
32	A:A:Y391	R:R:A128	36.8061	4	No	No	0	4	8
33	R:R:A128	R:R:Y135	16.9263	8.01	No	Yes	0	8	8
34	B:B:S331	B:B:V315	33.1809	3.23	No	Yes	6	9	7
35	B:B:D333	B:B:S331	33.1543	5.89	Yes	No	6	9	9
36	B:B:H311	B:B:K337	33.2673	14.41	Yes	Yes	6	9	6
37	B:B:F335	B:B:K337	33.3872	3.72	Yes	Yes	6	4	6
38	A:A:F219	A:A:H41	25.2176	7.92	Yes	No	0	8	6
39	A:A:H41	A:A:I383	26.3711	3.98	No	Yes	0	6	8
40	A:A:H387	A:A:I383	27.1321	6.63	Yes	Yes	9	8	8
41	A:A:H387	A:A:Q390	20.1344	4.95	Yes	No	0	8	4
42	A:A:Q390	A:A:Y391	20.321	13.53	No	No	0	4	4
43	A:A:H387	R:R:A128	20.5634	4.39	Yes	No	0	8	8
44	A:A:F219	A:A:L43	20.2237	3.65	Yes	No	0	8	7
45	A:A:I245	A:A:L43	19.8379	5.71	No	No	0	7	7
46	B:B:W332	B:B:Y59	32.8806	9.65	Yes	Yes	1	9	8
47	A:A:F290	A:A:I375	19.067	5.02	Yes	No	0	9	9
48	A:A:I245	A:A:I375	19.4524	5.89	No	No	0	7	9
49	A:A:C237	B:B:Y59	29.7763	6.72	No	Yes	1	8	8
50	A:A:C237	B:B:M101	30.1071	4.86	No	No	0	8	9
51	B:B:M101	B:B:R145	29.943	9.93	No	Yes	0	9	8
52	A:A:H387	R:R:P132	13.1748	3.05	Yes	Yes	9	8	9
53	A:A:W281	B:B:R314	19.7871	14.99	Yes	Yes	1	5	8
54	A:A:F273	A:A:W277	22.1463	7.02	Yes	Yes	1	9	6
55	A:A:H357	A:A:W277	40.3667	25.39	No	Yes	0	7	6
56	A:A:H357	A:A:R356	40.6785	3.39	No	No	0	7	2
57	A:A:R283	A:A:R356	41.0482	8.53	No	No	0	3	2
58	A:A:R280	A:A:R283	41.2638	4.26	No	No	0	5	3
59	A:A:R280	A:A:W281	40.6226	24.99	No	Yes	0	5	5
60	A:A:C359	A:A:W277	11.3264	3.92	Yes	Yes	1	5	6
61	A:A:L289	A:A:L291	10.3167	6.92	Yes	No	0	9	8
62	A:A:K338	A:A:V334	12.6749	3.04	Yes	Yes	1	5	4
63	A:A:F363	A:A:K338	15.8406	11.17	Yes	Yes	1	5	5
64	A:A:E344	A:A:F340	10.741	11.66	No	Yes	18	5	7
65	A:A:E344	A:A:L270	13.0471	6.63	No	Yes	0	5	6
66	R:R:L130	R:R:V129	13.0339	2.98	Yes	No	0	6	9
67	R:R:I139	R:R:Y127	15.1879	8.46	No	Yes	0	6	5
68	R:R:I139	R:R:Y135	15.5749	4.84	No	Yes	0	6	8
69	B:B:G162	B:B:R145	30.0711	6	No	Yes	2	9	8
70	B:B:G162	B:B:S161	30.0539	3.71	No	Yes	2	9	9
71	B:B:H142	B:B:S161	29.2655	15.34	Yes	Yes	2	9	9
72	B:B:H142	B:B:L146	10.8319	3.86	Yes	Yes	2	9	7
73	B:B:C149	B:B:L146	10.4915	3.17	Yes	Yes	2	8	7
74	B:B:C149	B:B:T102	20.8177	5.07	Yes	No	0	8	8
75	B:B:C148	B:B:T102	20.5883	3.38	No	No	0	6	8
76	B:B:K209	B:B:T221	12.0427	16.52	Yes	No	0	6	7
77	B:B:T221	G:G:Q18	11.335	5.67	No	No	0	7	9
78	B:B:H142	B:B:T159	13.2759	8.21	Yes	Yes	2	9	9
79	B:B:C149	B:B:T159	10.5397	3.38	Yes	Yes	2	8	9
80	B:B:C148	B:B:L190	13.3402	9.52	No	No	0	6	5
81	B:B:C271	B:B:D290	26.3425	4.67	No	Yes	1	5	6
82	B:B:C271	B:B:Y289	25.7485	4.03	No	Yes	1	5	7
83	B:B:W297	B:B:Y289	24.8324	9.65	Yes	Yes	1	8	7
84	B:B:W297	B:B:Y264	18.9892	15.43	Yes	Yes	1	8	5
85	B:B:L285	B:B:Y264	12.2129	9.38	Yes	Yes	0	6	5
86	B:B:F278	B:B:L285	11.8564	9.74	Yes	Yes	0	7	6
87	R:R:A317	R:R:N73	30.6074	4.69	No	No	0	9	9
88	R:R:A317	R:R:V41	30.4349	5.09	No	Yes	0	9	7
89	R:R:L81	R:R:V41	28.148	4.47	Yes	Yes	0	8	7
90	R:R:F314	R:R:L81	27.7618	12.18	Yes	Yes	0	7	8
91	R:R:F314	R:R:I34	13.3749	3.77	Yes	Yes	0	7	7
92	R:R:I34	R:R:W311	11.9309	14.09	Yes	Yes	0	7	7
93	R:R:F314	R:R:Y107	17.9617	7.22	Yes	Yes	4	7	8
94	A:A:W281	B:B:D290	21.2246	10.05	Yes	Yes	1	5	6
95	B:B:D290	B:B:T274	37.9404	4.34	Yes	No	1	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8KH4

PDB Summary
PDB	8KH4
Class	A
SubFamily	Orphan
Type	Orphan
SubType	GPR161
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	3.1
Date	2023-10-11
D.O.I.	10.1038/s41467-023-41654-3

Net Summary
I_min	2.98
Number of Linked Nodes	835
Number of Links	1073
Number of Hubs	197
Number of Links mediated by Hubs	694
Number of Communities	27
Number of Nodes involved in Communities	286
Number of Links involved in Communities	422

Path Summary
Number Of Nodes in MetaPath	96
Number Of Links MetaPath	95
Number of Shortest Paths	2736191
Length Of Smallest Path	3
Average Path Length	38.351
Length of Longest Path	71
Minimum Path Strength	1.215
Average Path Strength	7.13031
Maximum Path Strength	30.26
Minimum Path Correlation	0.7
Average Path Correlation	0.985343
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2
Average % Of Corr. Nodes	33.8213
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.8506
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • negative regulation of signaling • regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning • chordate embryonic development • negative regulation of biological process • pattern specification process • regulation of signal transduction • embryo development • negative regulation of cell communication • multicellular organism development • embryo development ending in birth or egg hatching • dorsal/ventral neural tube patterning • negative regulation of smoothened signaling pathway • negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning • anatomical structure development • negative regulation of cellular process • smoothened signaling pathway involved in dorsal/ventral neural tube patterning • regulation of smoothened signaling pathway • system development • developmental process • epithelium development • regulation of signaling • neural tube development • cell surface receptor signaling pathway • tube development • negative regulation of response to stimulus • nervous system development • tissue development • negative regulation of signal transduction • regionalization • smoothened signaling pathway • dorsal/ventral pattern formation • regulation of response to stimulus • neural tube patterning • regulation of cell communication • membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • intracellular anatomical structure • membrane • intracellular vesicle • intracellular membrane-bounded organelle • intracellular organelle • cytoplasmic vesicle membrane • bounding membrane of organelle • cytoplasmic vesicle
Gene Ontology	Cellular Component	• membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • intracellular anatomical structure • membrane • intracellular vesicle • intracellular membrane-bounded organelle • intracellular organelle • cytoplasmic vesicle membrane • bounding membrane of organelle • cytoplasmic vesicle • vesicle membrane • endocytic vesicle membrane • cytoplasm • vesicle • organelle membrane • endocytic vesicle • glial cell projection • endosome • recycling endosome • endomembrane system • plasma membrane • ciliary membrane • cell periphery • plasma membrane region • cell projection membrane • neuron projection • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • protein-containing complex binding • binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • protein binding • signaling receptor binding • G protein-coupled receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • D1 dopamine receptor binding • dopamine receptor binding • molecular function activator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase activator activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • cellular response to endogenous stimulus • response to hormone • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • extracellular membrane-bounded organelle • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • trans-Golgi network • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8KH4_Chain_A Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G A D N S G K S T I V K Q M R I F E T K F Q V D K V N F H M F D V G G Q R D E R R K W I Q C F N D V T A I I F V V D S S D Y N R L Q E A L N L F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N A R R I F N D C R D I I Q R M H L R Q Y E L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8KH4_Chain_B D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G R L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8KH4_Chain_G I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q8N6U8
Sequence	>8KH4_Chain_R I I T Q F I A I I V I T I F V C L G N L V I V V T L Y K K S Y L L T L S N K F V F S L T L S N F L L S V L V L P F V V T S S I R R E W I F G V V W C N F S A L L Y L L I S S A S M L T L G V I A I D R Y Y A V L Y P M V Y P M K I T G N R A V M A L V Y I W L H S L I G C L P P L F G W S S V E F D E F K W M C V A A W H R E P G Y T A F W Q I W C A L F P F L V M L V C Y G F I F R V A R V K A C K A L I T I L V V L G A F M V T W G P Y M V V I A S E A L W G K S S V S P S L E T W A T W L S F A S A V C H P L I Y G L W N K T V R K E L L G M Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8SMV	A	Orphan	Orphan	GPR161	Homo sapiens	-	-	Gs/β1/γ2	2.74	2024-02-21	10.1038/s41594-024-01223-8
	8SMV (No Gprot)	A	Orphan	Orphan	GPR161	Homo sapiens	-	-		2.74	2024-02-21	10.1038/s41594-024-01223-8
	8KH4	A	Orphan	Orphan	GPR161	Homo sapiens	-	-	Gs/β1/γ2	3.1	2023-10-11	10.1038/s41467-023-41654-3
	8KH4 (No Gprot)	A	Orphan	Orphan	GPR161	Homo sapiens	-	-		3.1	2023-10-11	10.1038/s41467-023-41654-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8KH4.zip

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