psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:T1	R:R:Y199	3.75	No	No	0	0	4
2	L:L:N5	L:L:Y9	22.1	No	No	0	0	0
3	L:L:N5	R:R:P205	6.52	No	No	0	0	4
4	L:L:R15	L:L:W8	4	No	No	3	0	0
5	L:L:W8	R:R:L210	4.56	No	Yes	3	0	4
6	L:L:Y9	R:R:H206	4.36	No	No	0	0	1
7	L:L:I14	L:L:S11	6.19	No	No	0	0	0
8	L:L:G13	R:R:P310	4.06	No	No	0	0	3
9	L:L:R15	R:R:V208	6.54	No	Yes	3	0	3
10	L:L:R15	R:R:L210	4.86	No	Yes	3	0	4
11	L:L:P16	R:R:E212	17.29	No	No	0	0	4
12	L:L:P16	R:R:R301	5.76	No	No	0	0	4
13	L:L:V17	R:R:A121	3.39	No	No	0	0	5
14	L:L:V17	R:R:Q317	7.16	No	No	0	0	4
15	L:L:V17	R:R:L318	4.47	No	No	0	0	3
16	L:L:G18	R:R:T117	5.46	No	No	0	0	6
17	L:L:F20	L:L:R19	12.83	Yes	Yes	0	0	0
18	L:L:R19	R:R:Y225	8.23	Yes	Yes	6	0	5
19	L:L:R19	R:R:L229	4.86	Yes	Yes	6	0	4
20	L:L:?21	L:L:F20	6.03	Yes	Yes	0	0	0
21	L:L:F20	R:R:V145	7.87	Yes	No	0	0	7
22	L:L:F20	R:R:Y146	5.16	Yes	Yes	0	0	7
23	L:L:F20	R:R:N298	3.62	Yes	No	0	0	6
24	L:L:?21	R:R:C113	7.86	Yes	No	1	0	7
25	L:L:?21	R:R:Q141	16.47	Yes	Yes	1	0	6
26	L:L:?21	R:R:H321	3.18	Yes	Yes	1	0	5
27	R:R:H57	R:R:K60	5.24	No	No	0	4	5
28	R:R:L59	R:R:L62	6.92	No	No	0	4	4
29	R:R:G61	R:R:K60	3.49	No	No	0	3	5
30	R:R:F122	R:R:K60	6.2	Yes	No	0	4	5
31	R:R:L66	R:R:Y67	4.69	No	Yes	1	5	8
32	R:R:L66	R:R:W322	12.53	No	No	1	5	5
33	R:R:V114	R:R:Y67	6.31	No	Yes	0	7	8
34	R:R:L318	R:R:Y67	3.52	No	Yes	0	3	8
35	R:R:H321	R:R:Y67	8.71	Yes	Yes	1	5	8
36	R:R:W322	R:R:Y67	5.79	No	Yes	1	5	8
37	R:R:V70	R:R:W322	6.13	No	No	0	7	5
38	R:R:C329	R:R:V70	3.42	No	No	0	7	7
39	R:R:V114	R:R:V71	4.81	No	No	0	7	7
40	R:R:G74	R:R:V73	3.68	No	Yes	0	8	5
41	R:R:C329	R:R:V73	3.42	No	Yes	0	7	5
42	R:R:F333	R:R:V73	3.93	No	Yes	0	6	5
43	R:R:A103	R:R:N78	4.69	No	Yes	0	9	9
44	R:R:D106	R:R:N78	10.77	Yes	Yes	2	9	9
45	R:R:N78	R:R:V107	2.96	Yes	No	0	9	7
46	R:R:N78	R:R:P332	11.4	Yes	No	2	9	9
47	R:R:I99	R:R:L81	4.28	No	No	0	8	9
48	R:R:A103	R:R:L81	4.73	No	No	0	9	9
49	R:R:L83	R:R:R87	3.64	No	No	0	4	5
50	R:R:L346	R:R:V84	5.96	No	No	0	7	8
51	R:R:I85	R:R:L91	4.28	No	No	7	7	7
52	R:R:I85	R:R:N96	4.25	No	No	7	7	8
53	R:R:L349	R:R:R87	3.64	No	No	0	6	5
54	R:R:L91	R:R:V88	4.47	No	No	0	7	5
55	R:R:E345	R:R:V88	12.84	No	No	0	5	5
56	R:R:H92	R:R:R89	9.03	No	No	0	6	6
57	R:R:E345	R:R:R90	10.47	No	No	8	5	5
58	R:R:K348	R:R:R90	4.95	No	No	8	4	5
59	R:R:L91	R:R:N96	12.36	No	No	7	7	8
60	R:R:N93	R:R:N96	16.35	No	No	0	7	8
61	R:R:D158	R:R:T95	5.78	Yes	No	0	8	8
62	R:R:F97	R:R:S176	5.28	No	No	0	6	7
63	R:R:L98	R:R:T154	2.95	No	No	0	7	7
64	R:R:I155	R:R:L98	4.28	Yes	No	0	8	7
65	R:R:D158	R:R:L98	4.07	Yes	No	0	8	7
66	R:R:N101	R:R:V180	7.39	No	No	0	9	7
67	R:R:D106	R:R:L102	6.79	Yes	No	0	9	9
68	R:R:L102	R:R:T151	5.9	No	No	0	9	7
69	R:R:L104	R:R:L108	5.54	No	No	0	6	7
70	R:R:M109	R:R:S105	3.07	Yes	No	2	8	8
71	R:R:S105	R:R:V147	4.85	No	Yes	0	8	7
72	R:R:S105	R:R:S148	4.89	No	No	2	8	9
73	R:R:D106	R:R:S148	2.94	Yes	No	2	9	9
74	R:R:A328	R:R:D106	4.63	No	Yes	0	9	9
75	R:R:D106	R:R:P332	3.22	Yes	No	2	9	9
76	R:R:M109	R:R:T144	7.53	Yes	No	0	8	8
77	R:R:M109	R:R:V145	3.04	Yes	No	0	8	7
78	R:R:M109	R:R:S148	6.13	Yes	No	2	8	9
79	R:R:A112	R:R:L140	3.15	No	No	0	3	5
80	R:R:C113	R:R:Q141	7.63	No	Yes	1	7	6
81	R:R:C113	R:R:H321	2.95	No	Yes	1	7	5
82	R:R:P115	R:R:V114	5.3	No	No	0	8	7
83	R:R:L116	R:R:T117	2.95	No	No	0	6	6
84	R:R:L116	R:R:V137	5.96	No	No	1	6	6
85	R:R:L116	R:R:Q141	3.99	No	Yes	1	6	6
86	R:R:F122	R:R:L118	6.09	Yes	No	0	4	7
87	R:R:A119	R:R:E123	4.53	No	No	0	5	4
88	R:R:W127	R:R:Y120	6.75	Yes	No	0	8	5
89	R:R:E212	R:R:Y120	4.49	No	No	0	4	5
90	R:R:D207	R:R:R125	7.15	No	No	0	4	5
91	R:R:R125	R:R:R209	3.2	No	No	0	5	5
92	R:R:F129	R:R:W127	5.01	No	Yes	0	7	8
93	R:R:C134	R:R:W127	6.53	Yes	Yes	0	9	8
94	R:R:R209	R:R:W127	4	No	Yes	0	5	8
95	R:R:F129	R:R:V128	7.87	No	No	0	7	3
96	R:R:G131	R:R:H200	3.18	No	No	0	2	5
97	R:R:L133	R:R:L136	4.15	No	No	0	6	4
98	R:R:L133	R:R:V137	2.98	No	No	0	6	6
99	R:R:C134	R:R:H135	8.85	Yes	No	0	9	7
100	R:R:C134	R:R:H200	4.42	Yes	No	0	9	5
101	R:R:C134	R:R:C211	3.64	Yes	No	0	9	9
102	R:R:Q141	R:R:V137	5.73	Yes	No	1	6	6
103	R:R:F138	R:R:T198	12.97	No	No	0	5	5
104	R:R:E213	R:R:F138	3.5	No	No	0	5	5
105	R:R:F139	R:R:V143	5.24	No	No	0	6	5
106	R:R:A195	R:R:F139	4.16	No	No	0	5	6
107	R:R:L140	R:R:T144	2.95	No	No	0	5	8
108	R:R:P142	R:R:Y146	5.56	No	Yes	0	5	7
109	R:R:A191	R:R:P142	3.74	No	No	0	7	5
110	R:R:S187	R:R:V143	4.85	No	No	0	8	5
111	R:R:S187	R:R:Y146	7.63	No	Yes	0	8	7
112	R:R:L229	R:R:Y146	5.86	Yes	Yes	0	4	7
113	R:R:I183	R:R:V147	3.07	No	Yes	0	7	7
114	R:R:V147	R:R:W184	19.61	Yes	No	0	7	9
115	R:R:S187	R:R:V147	3.23	No	Yes	0	8	7
116	R:R:P237	R:R:V149	3.53	Yes	No	0	9	8
117	R:R:F150	R:R:I183	7.54	No	No	0	6	7
118	R:R:F150	R:R:L186	3.65	No	No	0	6	4
119	R:R:I155	R:R:T151	3.04	Yes	No	0	8	7
120	R:R:L152	R:R:N331	5.49	No	No	4	8	9
121	R:R:L152	R:R:Y335	3.52	No	Yes	4	8	9
122	R:R:P237	R:R:T153	3.5	Yes	No	0	9	7
123	R:R:I155	R:R:R159	3.76	Yes	No	4	8	9
124	R:R:I155	R:R:Y335	6.04	Yes	Yes	4	8	9
125	R:R:A156	R:R:I241	6.5	No	No	9	9	8
126	R:R:A156	R:R:Y245	4	No	Yes	9	9	9
127	R:R:D158	R:R:R170	10.72	Yes	Yes	0	8	4
128	R:R:R159	R:R:Y335	11.32	No	Yes	4	9	9
129	R:R:V164	R:R:Y160	10.09	No	Yes	0	7	8
130	R:R:S244	R:R:Y160	7.63	No	Yes	0	8	8
131	R:R:R247	R:R:Y160	6.17	No	Yes	0	4	8
132	R:R:L163	R:R:V162	2.98	No	No	0	8	8
133	R:R:R170	R:R:V162	9.15	Yes	No	0	4	8
134	R:R:H165	R:R:V164	6.92	No	No	0	6	7
135	R:R:K251	R:R:V164	4.55	No	No	0	5	7
136	R:R:L167	R:R:P166	3.28	No	No	0	5	8
137	R:R:I171	R:R:L175	5.71	No	No	0	4	4
138	R:R:L173	R:R:S176	3	No	No	0	6	7
139	R:R:L186	R:R:L190	4.15	No	No	0	4	5
140	R:R:L192	R:R:P193	4.93	No	No	0	4	8
141	R:R:L192	R:R:V196	2.98	No	No	0	4	4
142	R:R:H197	R:R:Q221	16.07	No	Yes	0	5	4
143	R:R:H200	R:R:R209	7.9	No	No	0	5	5
144	R:R:L203	R:R:V201	4.47	No	No	0	1	1
145	R:R:F214	R:R:V201	5.24	Yes	No	0	4	1
146	R:R:E202	R:R:K204	18.9	No	No	0	2	1
147	R:R:L203	R:R:V208	2.98	No	Yes	3	1	3
148	R:R:L203	R:R:L210	8.3	No	Yes	3	1	4
149	R:R:H206	R:R:P205	3.05	No	No	0	1	4
150	R:R:L210	R:R:V208	2.98	Yes	Yes	3	4	3
151	R:R:F214	R:R:L210	3.65	Yes	Yes	0	4	4
152	R:R:E212	R:R:F214	7	No	Yes	0	4	4
153	R:R:Q218	R:R:W215	7.67	No	No	0	1	5
154	R:R:R222	R:R:W215	33.99	No	No	0	4	5
155	R:R:Q221	R:R:S217	4.33	Yes	No	0	4	3
156	R:R:E219	R:R:Q223	3.82	No	No	0	4	3
157	R:R:Q221	R:R:R222	3.5	Yes	No	0	4	4
158	R:R:Q221	R:R:Y225	5.64	Yes	Yes	0	4	5
159	R:R:P305	R:R:R222	5.76	No	No	0	3	4
160	R:R:L303	R:R:Q223	6.65	No	No	0	4	3
161	R:R:L229	R:R:Y225	3.52	Yes	Yes	6	4	5
162	R:R:A226	R:R:D302	3.09	No	No	0	5	5
163	R:R:L229	R:R:T233	4.42	Yes	No	0	4	5
164	R:R:H295	R:R:L230	3.86	Yes	No	0	8	6
165	R:R:L230	R:R:L299	5.54	No	No	0	6	5
166	R:R:L231	R:R:L235	6.92	No	No	0	5	4
167	R:R:H295	R:R:T233	6.85	Yes	No	0	8	5
168	R:R:L235	R:R:Y234	3.52	No	Yes	0	4	8
169	R:R:L238	R:R:Y234	3.52	No	Yes	0	6	8
170	R:R:L292	R:R:Y234	8.21	No	Yes	0	5	8
171	R:R:H295	R:R:Y234	9.8	Yes	Yes	0	8	8
172	R:R:L236	R:R:P237	4.93	No	Yes	0	5	9
173	R:R:A288	R:R:L238	3.15	No	No	0	6	6
174	R:R:I241	R:R:Y245	3.63	No	Yes	9	8	9
175	R:R:L242	R:R:V246	2.98	No	No	0	4	3
176	R:R:L280	R:R:Y245	7.03	No	Yes	0	7	9
177	R:R:I283	R:R:Y245	6.04	No	Yes	0	7	9
178	R:R:F277	R:R:S249	9.25	Yes	No	0	6	5
179	R:R:N254	R:R:V250	4.43	No	No	0	4	3
180	R:R:L252	R:R:R255	3.64	No	No	0	8	6
181	R:R:L252	R:R:R273	10.93	No	Yes	0	8	7
182	R:R:R253	R:R:R273	4.26	No	Yes	5	5	7
183	R:R:F277	R:R:R253	6.41	Yes	No	5	6	5
184	R:R:R255	R:R:R272	4.26	No	Yes	0	6	5
185	R:R:R272	R:R:W268	10	Yes	No	0	5	3
186	R:R:D269	R:R:R270	7.15	No	No	0	4	3
187	R:R:D269	R:R:R272	9.53	No	Yes	5	4	5
188	R:R:D269	R:R:R273	3.57	No	Yes	5	4	7
189	R:R:R272	R:R:R273	4.26	Yes	Yes	5	5	7
190	R:R:F277	R:R:R273	5.34	Yes	Yes	5	6	7
191	R:R:F277	R:R:R274	5.34	Yes	No	0	6	5
192	R:R:I283	R:R:L279	7.14	No	No	0	7	8
193	R:R:I334	R:R:V282	3.07	No	No	0	8	6
194	R:R:I283	R:R:Y335	3.63	No	Yes	0	7	9
195	R:R:F287	R:R:W291	16.04	No	No	0	9	8
196	R:R:C290	R:R:S327	6.89	No	No	0	9	9
197	R:R:H295	R:R:W291	8.46	Yes	No	0	8	8
198	R:R:S327	R:R:W291	8.65	No	No	0	9	8
199	R:R:L292	R:R:P293	4.93	No	No	0	5	9
200	R:R:L323	R:R:P293	3.28	No	No	0	8	9
201	R:R:L294	R:R:N298	5.49	No	No	0	7	6
202	R:R:A324	R:R:L294	6.3	No	No	0	8	7
203	R:R:L300	R:R:V296	2.98	No	No	0	5	5
204	R:R:F297	R:R:F313	6.43	No	No	0	4	4
205	R:R:F297	R:R:V316	5.24	No	No	0	4	5
206	R:R:C320	R:R:F297	5.59	No	No	0	7	4
207	R:R:L299	R:R:L303	8.3	No	No	10	5	4
208	R:R:F313	R:R:R301	9.62	No	No	0	4	4
209	R:R:Q317	R:R:R301	12.85	No	No	0	4	4
210	R:R:D304	R:R:P305	6.44	No	No	0	3	3
211	R:R:D304	R:R:H306	13.87	No	No	0	3	2
212	R:R:A307	R:R:D309	3.09	No	No	0	2	1
213	R:R:H321	R:R:M325	7.88	Yes	No	0	5	7
214	R:R:N331	R:R:Y335	3.49	No	Yes	4	9	9
215	R:R:F333	R:R:W337	15.03	No	No	0	6	7
216	R:R:A336	R:R:W337	6.48	No	No	0	7	7
217	R:R:L346	R:R:W337	4.56	No	No	0	7	7
218	R:R:F342	R:R:S341	6.61	No	No	0	8	6
219	R:R:E345	R:R:K348	8.1	No	No	8	5	4
220	R:R:N93	R:R:T95	2.92	No	No	0	7	8
221	R:R:N101	R:R:T151	2.92	No	No	0	9	7
222	R:R:F287	R:R:P237	2.89	No	Yes	0	9	9
223	R:R:Q58	R:R:V56	2.87	No	No	0	2	2
224	R:R:I63	R:R:L62	2.85	No	No	0	5	4
225	R:R:I334	R:R:L279	2.85	No	No	0	8	8
226	L:L:P2	R:R:Y199	2.78	No	No	0	0	4
227	R:R:P193	R:R:Y225	2.78	No	Yes	0	8	5
228	R:R:L346	R:R:L80	2.77	No	No	0	7	6
229	R:R:A119	R:R:F129	2.77	No	No	0	5	7
230	R:R:A194	R:R:F138	2.77	No	No	0	4	5
231	R:R:A336	R:R:F342	2.77	No	No	0	7	8
232	R:R:H135	R:R:T198	2.74	No	No	0	7	5
233	R:R:C329	R:R:Y330	2.69	No	No	0	7	6
234	R:R:F122	R:R:V64	2.62	Yes	No	0	4	5
235	R:R:R170	R:R:V94	2.62	Yes	No	0	4	6
236	R:R:F97	R:R:V180	2.62	No	No	0	6	7
237	R:R:H339	R:R:L338	2.57	No	No	0	8	7
238	R:R:Q54	R:R:Q58	2.56	No	No	0	3	2
239	R:R:S326	R:R:Y330	2.54	No	No	0	5	6
240	R:R:V56	R:R:Y311	2.52	No	No	0	2	3
241	R:R:V248	R:R:Y160	2.52	No	Yes	0	8	8
242	R:R:V284	R:R:Y245	2.52	No	Yes	0	7	9
243	R:R:F277	R:R:L280	2.44	Yes	No	0	6	7
244	R:R:I63	R:R:Y67	2.42	No	Yes	0	5	8
245	R:R:D309	R:R:F313	2.39	No	No	0	1	4
246	L:L:R19	R:R:D302	2.38	Yes	No	0	0	5
247	R:R:D340	R:R:R343	2.38	No	No	0	5	8
248	R:R:L231	R:R:W227	2.28	No	No	0	5	5
249	R:R:L299	R:R:W227	2.28	No	No	10	5	5
250	R:R:L303	R:R:W227	2.28	No	No	10	4	5
251	R:R:G130	R:R:G131	2.11	No	No	0	8	2
252	R:R:G131	R:R:G132	2.11	No	No	0	2	2
253	R:R:F214	R:R:Y199	2.06	Yes	No	0	4	4
254	L:L:P2	R:R:G216	2.03	No	No	0	0	3
255	R:R:A103	R:R:G100	1.95	No	No	0	9	6
256	R:R:G77	R:R:V76	1.84	No	No	0	8	5
257	R:R:G126	R:R:V208	1.84	No	Yes	0	5	3
258	R:R:G228	R:R:L231	1.71	No	No	0	4	5
259	R:R:C290	R:R:V286	1.71	No	No	0	9	7
260	R:R:A312	R:R:V316	1.7	No	No	0	4	5
261	L:L:I4	L:L:P2	1.69	No	No	0	0	0
262	L:L:I4	L:L:P6	1.69	No	No	0	0	0
263	R:R:K204	R:R:P205	1.67	No	No	0	1	4
264	R:R:G314	R:R:Q317	1.64	No	No	0	3	4
265	L:L:N5	L:L:P6	1.63	No	No	0	0	0
266	L:L:A7	L:L:I4	1.62	No	No	0	0	0
267	R:R:S68	R:R:V69	1.62	No	No	0	5	4
268	R:R:S244	R:R:V240	1.62	No	No	0	8	7
269	R:R:D309	R:R:P310	1.61	No	No	0	1	3
270	R:R:V69	R:R:V73	1.6	No	Yes	0	4	5
271	R:R:V72	R:R:V73	1.6	No	Yes	0	6	5
272	R:R:V246	R:R:V250	1.6	No	No	0	3	3
273	R:R:V281	R:R:V282	1.6	No	No	0	5	6
274	R:R:V285	R:R:V286	1.6	No	No	0	4	7
275	R:R:V285	R:R:V289	1.6	No	No	0	4	6
276	R:R:T153	R:R:V240	1.59	No	No	0	7	7
277	R:R:E123	R:R:P124	1.57	No	No	0	4	4
278	R:R:H165	R:R:P166	1.53	No	No	0	6	8
279	R:R:L65	R:R:S68	1.5	No	No	0	6	5
280	R:R:L175	R:R:S172	1.5	No	No	0	4	4
281	R:R:L75	R:R:V107	1.49	No	No	0	6	7
282	R:R:L80	R:R:V76	1.49	No	No	0	6	5
283	R:R:L349	R:R:V84	1.49	No	No	0	6	8
284	R:R:L104	R:R:V107	1.49	No	No	0	6	7
285	R:R:L190	R:R:V232	1.49	No	No	0	5	4
286	R:R:L242	R:R:V284	1.49	No	No	0	4	7
287	R:R:L292	R:R:V296	1.49	No	No	0	5	5
288	R:R:L280	R:R:T276	1.47	No	No	0	7	7
289	R:R:D340	R:R:S341	1.47	No	No	0	5	6
290	R:R:D158	R:R:V161	1.46	Yes	No	0	8	5
291	L:L:D3	L:L:T1	1.45	No	No	0	0	0
292	R:R:I63	R:R:L315	1.43	No	No	0	5	1
293	R:R:I334	R:R:L338	1.43	No	No	0	8	7
294	R:R:A121	R:R:F122	1.39	No	Yes	0	5	4
295	R:R:A188	R:R:F139	1.39	No	No	0	4	6
296	R:R:L59	R:R:Q58	1.33	No	No	0	4	2
297	R:R:R174	R:R:S172	1.32	No	No	0	6	4
298	R:R:D340	R:R:E344	1.3	No	No	0	5	4
299	R:R:I171	R:R:R170	1.25	No	Yes	0	4	4
300	L:L:R12	R:R:L55	1.21	No	No	0	0	3
301	R:R:L175	R:R:Y178	1.17	No	No	0	4	3
302	R:R:L224	R:R:Y225	1.17	No	Yes	0	3	5
303	R:R:H165	R:R:R168	1.13	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:R19	7.075	4	6	0
2	L:L:F20	7.102	5	0	0
3	L:L:?21	8.385	4	1	0
4	R:R:Y67	5.24	6	1	8
5	R:R:V73	2.846	5	0	5
6	R:R:N78	7.455	4	2	9
7	R:R:D106	5.67	5	2	9
8	R:R:M109	4.9425	4	2	8
9	R:R:F122	4.075	4	0	4
10	R:R:W127	5.5725	4	0	8
11	R:R:C134	5.86	4	0	9
12	R:R:Q141	8.455	4	1	6
13	R:R:Y146	6.0525	4	0	7
14	R:R:V147	7.69	4	0	7
15	R:R:I155	4.28	4	4	8
16	R:R:D158	5.5075	4	0	8
17	R:R:Y160	6.6025	4	0	8
18	R:R:R170	5.935	4	0	4
19	R:R:V208	3.585	4	3	3
20	R:R:L210	4.87	5	3	4
21	R:R:F214	4.4875	4	0	4
22	R:R:Q221	7.385	4	0	4
23	R:R:Y225	4.268	5	6	5
24	R:R:L229	4.665	4	6	4
25	R:R:Y234	6.2625	4	0	8
26	R:R:P237	3.7125	4	0	9
27	R:R:Y245	4.644	5	9	9
28	R:R:R272	7.0125	4	5	5
29	R:R:R273	5.672	5	5	7
30	R:R:F277	5.756	5	5	6
31	R:R:H295	7.2425	4	0	8
32	R:R:H321	5.68	4	1	5
33	R:R:Y335	5.6	5	4	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:I4	L:L:P6	10.4653	1.69	No	No	0	0	0
2	L:L:I4	L:L:P2	13.0019	1.69	No	No	0	0	0
3	L:L:P2	R:R:Y199	15.5021	2.78	No	No	0	0	4
4	R:R:F214	R:R:Y199	19.2019	2.06	Yes	No	0	4	4
5	R:R:F313	R:R:R301	11.7255	9.62	No	No	0	4	4
6	L:L:P16	R:R:R301	57.7793	5.76	No	No	0	0	4
7	L:L:P16	R:R:E212	56.8422	17.29	No	No	0	0	4
8	R:R:E212	R:R:F214	29.8287	7	No	Yes	0	4	4
9	R:R:Q317	R:R:R301	66.6007	12.85	No	No	0	4	4
10	L:L:V17	R:R:Q317	68.3012	7.16	No	No	0	0	4
11	L:L:V17	R:R:L318	74.6991	4.47	No	No	0	0	3
12	L:L:?21	R:R:H321	96.385	3.18	Yes	Yes	1	0	5
13	R:R:H321	R:R:Y67	99.2124	8.71	Yes	Yes	1	5	8
14	R:R:L318	R:R:Y67	75.4625	3.52	No	Yes	0	3	8
15	L:L:?21	L:L:F20	100	6.03	Yes	Yes	0	0	0
16	L:L:F20	L:L:R19	49.5921	12.83	Yes	Yes	0	0	0
17	L:L:R19	R:R:Y225	11.8709	8.23	Yes	Yes	6	0	5
18	L:L:R19	R:R:L229	35.9157	4.86	Yes	Yes	6	0	4
19	L:L:F20	R:R:Y146	44.107	5.16	Yes	Yes	0	0	7
20	R:R:L229	R:R:Y146	51.8943	5.86	Yes	Yes	0	4	7
21	L:L:F20	R:R:V145	75.7573	7.87	Yes	No	0	0	7
22	R:R:I63	R:R:Y67	10.4653	2.42	No	Yes	0	5	8
23	R:R:W322	R:R:Y67	32.9388	5.79	No	Yes	1	5	8
24	R:R:V70	R:R:W322	31.921	6.13	No	No	0	7	5
25	R:R:C329	R:R:V70	30.786	3.42	No	No	0	7	7
26	R:R:C329	R:R:V73	27.3326	3.42	No	Yes	0	7	5
27	R:R:F333	R:R:V73	20.2076	3.93	No	Yes	0	6	5
28	R:R:M109	R:R:V145	75.1595	3.04	Yes	No	0	8	7
29	R:R:M109	R:R:S148	72.0252	6.13	Yes	No	2	8	9
30	R:R:D106	R:R:S148	88.9167	2.94	Yes	No	2	9	9
31	R:R:D106	R:R:N78	13.0826	10.77	Yes	Yes	2	9	9
32	R:R:F333	R:R:W337	18.9918	15.03	No	No	0	6	7
33	R:R:L346	R:R:W337	10.2472	4.56	No	No	0	7	7
34	R:R:D106	R:R:L102	77.6719	6.79	Yes	No	0	9	9
35	R:R:L102	R:R:T151	76.6823	5.9	No	No	0	9	7
36	R:R:I155	R:R:T151	70.5752	3.04	Yes	No	0	8	7
37	R:R:I155	R:R:L98	30.7779	4.28	Yes	No	0	8	7
38	R:R:D158	R:R:L98	28.1162	4.07	Yes	No	0	8	7
39	R:R:D158	R:R:T95	13.0261	5.78	Yes	No	0	8	8
40	R:R:N93	R:R:T95	11.6124	2.92	No	No	0	7	8
41	R:R:N93	R:R:N96	10.1785	16.35	No	No	0	7	8
42	R:R:S187	R:R:Y146	23.346	7.63	No	Yes	0	8	7
43	R:R:S187	R:R:V147	21.2255	3.23	No	Yes	0	8	7
44	R:R:E212	R:R:Y120	30.9758	4.49	No	No	0	4	5
45	R:R:W127	R:R:Y120	29.853	6.75	Yes	No	0	8	5
46	R:R:C134	R:R:W127	14.0318	6.53	Yes	Yes	0	9	8
47	R:R:L229	R:R:T233	86.9658	4.42	Yes	No	0	4	5
48	R:R:H295	R:R:T233	85.0028	6.85	Yes	No	0	8	5
49	R:R:H295	R:R:W291	48.2874	8.46	Yes	No	0	8	8
50	R:R:F287	R:R:W291	35.4673	16.04	No	No	0	9	8
51	R:R:F287	R:R:P237	33.3024	2.89	No	Yes	0	9	9
52	R:R:I155	R:R:Y335	43.1255	6.04	Yes	Yes	4	8	9
53	R:R:P237	R:R:T153	26.759	3.5	Yes	No	0	9	7
54	R:R:I283	R:R:Y335	39.4983	3.63	No	Yes	0	7	9
55	R:R:I283	R:R:Y245	30.5154	6.04	No	Yes	0	7	9
56	R:R:D158	R:R:R170	13.0261	10.72	Yes	Yes	0	8	4
57	R:R:T153	R:R:V240	24.5618	1.59	No	No	0	7	7
58	R:R:S244	R:R:V240	22.3564	1.62	No	No	0	8	7
59	R:R:S244	R:R:Y160	20.143	7.63	No	Yes	0	8	8
60	R:R:V164	R:R:Y160	13.4542	10.09	No	Yes	0	7	8
61	R:R:H295	R:R:L230	13.4906	3.86	Yes	No	0	8	6
62	R:R:L230	R:R:L299	11.261	5.54	No	No	0	6	5
63	R:R:H295	R:R:Y234	24.5981	9.8	Yes	Yes	0	8	8
64	R:R:L292	R:R:Y234	11.4064	8.21	No	Yes	0	5	8
65	R:R:L280	R:R:Y245	19.7875	7.03	No	Yes	0	7	9
66	R:R:F277	R:R:L280	17.0733	2.44	Yes	No	0	6	7
67	R:R:F277	R:R:R273	11.4347	5.34	Yes	Yes	5	6	7
68	R:R:S327	R:R:W291	11.3458	8.65	No	No	0	9	8
69	R:R:S105	R:R:V147	17.974	4.85	No	Yes	0	8	7
70	R:R:S105	R:R:S148	17.772	4.89	No	No	2	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:T1	R:R:Y199	3.75	0	No	No	0	4	0	1
L:L:N5	R:R:P205	6.52	0	No	No	0	4	0	1
L:L:W8	R:R:L210	4.56	3	No	Yes	0	4	0	1
L:L:Y9	R:R:H206	4.36	0	No	No	0	1	0	1
L:L:G13	R:R:P310	4.06	0	No	No	0	3	0	1
L:L:R15	R:R:V208	6.54	3	No	Yes	0	3	0	1
L:L:R15	R:R:L210	4.86	3	No	Yes	0	4	0	1
L:L:P16	R:R:E212	17.29	0	No	No	0	4	0	1
L:L:P16	R:R:R301	5.76	0	No	No	0	4	0	1
L:L:V17	R:R:A121	3.39	0	No	No	0	5	0	1
L:L:V17	R:R:Q317	7.16	0	No	No	0	4	0	1
L:L:V17	R:R:L318	4.47	0	No	No	0	3	0	1
L:L:G18	R:R:T117	5.46	0	No	No	0	6	0	1
L:L:R19	R:R:Y225	8.23	6	Yes	Yes	0	5	0	1
L:L:R19	R:R:L229	4.86	6	Yes	Yes	0	4	0	1
L:L:F20	R:R:V145	7.87	0	Yes	No	0	7	0	1
L:L:F20	R:R:Y146	5.16	0	Yes	Yes	0	7	0	1
L:L:F20	R:R:N298	3.62	0	Yes	No	0	6	0	1
L:L:?21	R:R:C113	7.86	1	Yes	No	0	7	0	1
L:L:?21	R:R:Q141	16.47	1	Yes	Yes	0	6	0	1
L:L:?21	R:R:H321	3.18	1	Yes	Yes	0	5	0	1
R:R:L318	R:R:Y67	3.52	0	No	Yes	3	8	1	2
R:R:H321	R:R:Y67	8.71	1	Yes	Yes	5	8	1	2
R:R:M109	R:R:V145	3.04	2	Yes	No	8	7	2	1
R:R:C113	R:R:Q141	7.63	1	No	Yes	7	6	1	1
R:R:C113	R:R:H321	2.95	1	No	Yes	7	5	1	1
R:R:L116	R:R:T117	2.95	1	No	No	6	6	2	1
R:R:L116	R:R:V137	5.96	1	No	No	6	6	2	2
R:R:L116	R:R:Q141	3.99	1	No	Yes	6	6	2	1
R:R:E212	R:R:Y120	4.49	0	No	No	4	5	1	2
R:R:Q141	R:R:V137	5.73	1	Yes	No	6	6	1	2
R:R:P142	R:R:Y146	5.56	0	No	Yes	5	7	2	1
R:R:S187	R:R:Y146	7.63	0	No	Yes	8	7	2	1
R:R:L229	R:R:Y146	5.86	6	Yes	Yes	4	7	1	1
R:R:L203	R:R:V208	2.98	3	No	Yes	1	3	2	1
R:R:L203	R:R:L210	8.3	3	No	Yes	1	4	2	1
R:R:H206	R:R:P205	3.05	0	No	No	1	4	1	1
R:R:L210	R:R:V208	2.98	3	Yes	Yes	4	3	1	1
R:R:F214	R:R:L210	3.65	0	Yes	Yes	4	4	2	1
R:R:E212	R:R:F214	7	0	No	Yes	4	4	1	2
R:R:Q221	R:R:Y225	5.64	0	Yes	Yes	4	5	2	1
R:R:L229	R:R:Y225	3.52	6	Yes	Yes	4	5	1	1
R:R:A226	R:R:D302	3.09	0	No	No	5	5	2	1
R:R:L229	R:R:T233	4.42	6	Yes	No	4	5	1	2
R:R:L294	R:R:N298	5.49	0	No	No	7	6	2	1
R:R:F313	R:R:R301	9.62	0	No	No	4	4	2	1
R:R:Q317	R:R:R301	12.85	0	No	No	4	4	1	1
R:R:H321	R:R:M325	7.88	1	Yes	No	5	7	1	2
L:L:P2	R:R:Y199	2.78	0	No	No	0	4	0	1
R:R:P193	R:R:Y225	2.78	0	No	Yes	8	5	2	1
R:R:D309	R:R:F313	2.39	0	No	No	1	4	2	2
L:L:R19	R:R:D302	2.38	6	Yes	No	0	5	0	1
R:R:F214	R:R:Y199	2.06	0	Yes	No	4	4	2	1
L:L:P2	R:R:G216	2.03	0	No	No	0	3	0	1
R:R:G126	R:R:V208	1.84	0	No	Yes	5	3	2	1
R:R:K204	R:R:P205	1.67	0	No	No	1	4	2	1
R:R:G314	R:R:Q317	1.64	0	No	No	3	4	2	1
R:R:D309	R:R:P310	1.61	0	No	No	1	3	2	1
R:R:A121	R:R:F122	1.39	0	No	Yes	5	4	1	2
L:L:R12	R:R:L55	1.21	0	No	No	0	3	0	1
R:R:L224	R:R:Y225	1.17	0	No	Yes	3	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8ZPS_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.94
Number of Linked Nodes	282
Number of Links	303
Number of Hubs	33
Number of Links mediated by Hubs	123
Number of Communities	10
Number of Nodes involved in Communities	45
Number of Links involved in Communities	53

Path Summary
Number Of Nodes in MetaPath	71
Number Of Links MetaPath	70
Number of Shortest Paths	52351
Length Of Smallest Path	3
Average Path Length	16.5637
Length of Longest Path	35
Minimum Path Strength	1.33
Average Path Strength	5.86126
Maximum Path Strength	20.83
Minimum Path Correlation	0.7
Average Path Correlation	0.934957
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	50.7674
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.2425
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• multi-multicellular organism process • multicellular organismal process • reproductive process • female pregnancy • multi-organism reproductive process • regulation of hormone levels • biological regulation • metabolic process • cellular process • regulation of biological quality • hormone metabolic process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • G protein-coupled receptor signaling pathway • signal transduction • cell communication • behavior • feeding behavior • membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • cell periphery • plasma membrane • membrane • neuron projection • protein binding • binding • prolactin-releasing peptide receptor binding • signaling receptor binding • G protein-coupled receptor binding • neuropeptide receptor binding • hormone activity • molecular function activator activity • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • neuropeptide activity • neuropeptide hormone activity • reduction of food intake in response to dietary excess • response to nutrient levels • homeostatic process • eating behavior • multicellular organismal-level homeostasis • response to dietary excess • energy homeostasis • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • developmental process • multicellular organism development • anatomical structure development • autonomic nervous system development • nervous system development • system development • response to insulin • fat cell differentiation • cellular developmental process • cell differentiation • anatomical structure homeostasis • tissue homeostasis • primary metabolic process • lipid metabolic process • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • response to hexose • response to monosaccharide • response to carbohydrate • response to glucose • regulation of multicellular organism growth • regulation of growth • regulation of developmental growth • regulation of developmental process • developmental growth • growth • multicellular organism growth • regulation of multicellular organismal process • extracellular region • intracellular anatomical structure • cytoplasm • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of smell • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • skeletal system development • bone development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?21
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P49683
Sequence	>8ZPS_nogp_Chain_R Q L V H Q L K G L I V L L Y S V V V V V G L V G N C L L V L V I A R V R R L H N V T N F L I G N L A L S D V L M C T A C V P L T L A Y A F E P R G W V F G G G L C H L V F F L Q P V T V Y V S V F T L T T I A V D R Y V V L V H P L R R R I S L R L S A Y A V L A I W A L S A V L A L P A A V H T Y H V E L K P H D V R L C E E F W G S Q E R Q R Q L Y A W G L L L V T Y L L P L L V I L L S Y V R V S V K L R N R V A D W D R A R R R R T F C L L V V I V V V F A V C W L P L H V F N L L R D L D P H A I D P Y A F G L V Q L L C H W L A M S S A C Y N P F I Y A W L H D S F R E E L R K L L V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZPS	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP20	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.97	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPS (No Gprot)	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP20	-		2.97	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPT	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP20	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.96	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPT (No Gprot)	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP20	-		2.96	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	9K26	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP31	-	Gi1/β1/γ2	3	2025-01-29	To be published
	9K26 (No Gprot)	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP31	-		3	2025-01-29	To be published
	9K27	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP31	-	chim(NtGi1-Gq)/β1/γ2	2.68	2025-01-29	To be published
	9K27 (No Gprot)	A	Peptide	Prolactin-releasing peptide	PrRP	Homo sapiens	PrRP31	-		2.68	2025-01-29	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ZPS_nogp.zip

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