psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L53	R:R:Q54	5.32	No	No	0	3	3
2	R:R:H57	R:R:L53	12.86	No	No	0	4	3
3	L:L:R26	R:R:L53	3.64	No	No	0	0	3
4	R:R:L55	R:R:Y311	4.69	No	No	0	3	3
5	R:R:L59	R:R:Q58	5.32	No	No	0	4	2
6	R:R:L315	R:R:L59	4.15	No	No	0	1	4
7	R:R:F122	R:R:K60	7.44	Yes	No	0	4	5
8	R:R:L66	R:R:W322	14.81	No	Yes	0	5	5
9	R:R:V114	R:R:Y67	6.31	No	Yes	0	7	8
10	R:R:L118	R:R:Y67	7.03	No	Yes	0	7	8
11	R:R:L318	R:R:Y67	3.52	No	Yes	0	3	8
12	R:R:H321	R:R:Y67	9.8	No	Yes	0	5	8
13	R:R:W322	R:R:Y67	4.82	Yes	Yes	0	5	8
14	R:R:V70	R:R:W322	4.9	No	Yes	0	7	5
15	R:R:C329	R:R:V70	5.12	Yes	No	0	7	7
16	R:R:C329	R:R:V73	5.12	Yes	No	0	7	5
17	R:R:C79	R:R:L75	3.17	No	No	0	4	6
18	R:R:G77	R:R:V76	3.68	No	No	0	8	5
19	R:R:A103	R:R:N78	4.69	No	No	0	9	9
20	R:R:D106	R:R:N78	6.73	Yes	No	0	9	9
21	R:R:N78	R:R:P332	9.77	No	No	0	9	9
22	R:R:C79	R:R:V107	3.42	No	No	0	4	7
23	R:R:L80	R:R:W337	3.42	No	Yes	0	6	7
24	R:R:I85	R:R:L81	4.28	No	Yes	0	7	9
25	R:R:A103	R:R:L81	3.15	No	Yes	0	9	9
26	R:R:A336	R:R:L81	3.15	No	Yes	7	7	9
27	R:R:L81	R:R:W337	7.97	Yes	Yes	7	9	7
28	R:R:E345	R:R:V84	5.7	Yes	No	0	5	8
29	R:R:R90	R:R:V88	5.23	No	No	5	5	5
30	R:R:L91	R:R:V88	4.47	No	No	5	7	5
31	R:R:E345	R:R:V88	7.13	Yes	No	5	5	5
32	R:R:H92	R:R:R89	4.51	No	No	0	6	6
33	R:R:L91	R:R:R90	6.07	No	No	5	7	5
34	R:R:E345	R:R:R90	5.82	Yes	No	5	5	5
35	R:R:L91	R:R:N96	6.87	No	No	0	7	8
36	R:R:N93	R:R:T95	4.39	No	No	0	7	8
37	R:R:N93	R:R:N96	12.26	No	No	0	7	8
38	R:R:R170	R:R:V94	9.15	Yes	No	0	4	6
39	R:R:S176	R:R:V94	3.23	No	No	0	7	6
40	R:R:F342	R:R:N96	3.62	No	No	0	8	8
41	R:R:F97	R:R:N101	15.71	No	No	0	6	9
42	R:R:F97	R:R:S176	7.93	No	No	0	6	7
43	R:R:D158	R:R:L98	4.07	No	No	0	8	7
44	R:R:N101	R:R:V180	5.91	No	No	0	9	7
45	R:R:D106	R:R:L102	5.43	Yes	Yes	4	9	9
46	R:R:L102	R:R:T151	4.42	Yes	No	0	9	7
47	R:R:I155	R:R:L102	4.28	No	Yes	0	8	9
48	R:R:L102	R:R:N331	8.24	Yes	Yes	4	9	9
49	R:R:S105	R:R:V147	4.85	No	Yes	0	8	7
50	R:R:S105	R:R:S148	6.52	No	No	0	8	9
51	R:R:D106	R:R:S148	4.42	Yes	No	0	9	9
52	R:R:D106	R:R:N331	6.73	Yes	Yes	4	9	9
53	R:R:M109	R:R:T144	6.02	Yes	No	0	8	8
54	R:R:M109	R:R:V145	6.09	Yes	No	0	8	7
55	R:R:M109	R:R:S148	4.6	Yes	No	0	8	9
56	R:R:A112	R:R:T144	3.36	No	No	0	3	8
57	R:R:C113	R:R:M325	3.24	No	No	0	7	7
58	L:L:?33	R:R:C113	3.93	Yes	No	0	0	7
59	R:R:P115	R:R:V114	5.3	No	No	0	8	7
60	R:R:L116	R:R:W127	4.56	No	Yes	0	6	8
61	R:R:L116	R:R:V137	8.94	No	No	0	6	6
62	R:R:Q141	R:R:T117	4.25	No	No	3	6	6
63	L:L:V28	R:R:T117	3.17	No	No	0	0	6
64	L:L:?33	R:R:T117	3.65	Yes	No	3	0	6
65	R:R:F122	R:R:L118	3.65	Yes	No	0	4	7
66	R:R:W127	R:R:Y120	3.86	Yes	No	0	8	5
67	L:L:R26	R:R:Y120	5.14	No	No	0	0	5
68	L:L:V28	R:R:Y120	5.05	No	No	0	0	5
69	R:R:E123	R:R:R125	3.49	Yes	No	2	4	5
70	R:R:E123	R:R:V128	4.28	Yes	No	2	4	3
71	R:R:R125	R:R:V128	5.23	No	No	2	5	3
72	R:R:F129	R:R:W127	4.01	Yes	Yes	2	7	8
73	R:R:L133	R:R:W127	3.42	No	Yes	2	6	8
74	R:R:C134	R:R:W127	5.22	Yes	Yes	2	9	8
75	R:R:H200	R:R:W127	8.46	Yes	Yes	2	5	8
76	R:R:C211	R:R:W127	5.22	Yes	Yes	2	9	8
77	R:R:F129	R:R:L133	6.09	Yes	No	2	7	6
78	R:R:G130	R:R:H200	3.18	No	Yes	0	8	5
79	R:R:G131	R:R:H200	9.53	No	Yes	0	2	5
80	R:R:C134	R:R:H135	4.42	Yes	No	0	9	7
81	R:R:C134	R:R:H200	8.85	Yes	Yes	2	9	5
82	R:R:C134	R:R:C211	7.28	Yes	Yes	2	9	9
83	R:R:L136	R:R:L140	6.92	No	No	0	4	5
84	R:R:Q141	R:R:V137	4.3	No	No	0	6	6
85	R:R:C211	R:R:F138	8.38	Yes	No	0	9	5
86	R:R:F139	R:R:V143	3.93	No	No	0	6	5
87	R:R:A195	R:R:F139	4.16	No	No	0	5	6
88	L:L:?33	R:R:Q141	16.47	Yes	No	3	0	6
89	R:R:P142	R:R:Y146	5.56	No	Yes	0	5	7
90	R:R:A191	R:R:P142	3.74	No	No	0	7	5
91	R:R:S187	R:R:V143	4.85	No	No	0	8	5
92	R:R:V145	R:R:Y146	5.05	No	Yes	3	7	7
93	L:L:F31	R:R:V145	18.35	Yes	No	3	0	7
94	R:R:S187	R:R:Y146	5.09	No	Yes	0	8	7
95	R:R:L229	R:R:Y146	4.69	No	Yes	3	4	7
96	R:R:T233	R:R:Y146	8.74	No	Yes	0	5	7
97	L:L:F31	R:R:Y146	7.22	Yes	Yes	3	0	7
98	R:R:V147	R:R:W184	12.26	Yes	No	0	7	9
99	R:R:S187	R:R:V147	3.23	No	Yes	0	8	7
100	R:R:P237	R:R:V149	3.53	No	No	0	9	8
101	R:R:F150	R:R:I183	5.02	No	No	0	6	7
102	R:R:F150	R:R:L186	3.65	No	No	0	6	4
103	R:R:F287	R:R:L152	4.87	No	No	0	9	8
104	R:R:L152	R:R:N331	4.12	No	Yes	4	8	9
105	R:R:L152	R:R:Y335	4.69	No	Yes	4	8	9
106	R:R:P237	R:R:T153	3.5	No	No	0	9	7
107	R:R:I183	R:R:T154	4.56	No	No	0	7	7
108	R:R:I155	R:R:Y335	3.63	No	Yes	0	8	9
109	R:R:A156	R:R:I241	3.25	No	No	0	9	8
110	R:R:A156	R:R:Y245	4	No	Yes	0	9	9
111	R:R:D158	R:R:R170	9.53	No	Yes	0	8	4
112	R:R:R159	R:R:Y245	9.26	No	Yes	4	9	9
113	R:R:I283	R:R:R159	3.76	Yes	No	4	7	9
114	R:R:R159	R:R:Y335	7.2	No	Yes	4	9	9
115	R:R:V164	R:R:Y160	8.83	No	No	0	7	8
116	R:R:S244	R:R:Y160	6.36	No	No	0	8	8
117	R:R:R247	R:R:Y160	9.26	No	No	0	4	8
118	R:R:R170	R:R:V162	5.23	Yes	No	0	4	8
119	R:R:H165	R:R:V164	11.07	No	No	0	6	7
120	R:R:I171	R:R:L175	4.28	No	No	0	4	4
121	R:R:L173	R:R:S176	4.5	No	No	0	6	7
122	R:R:R174	R:R:Y178	11.32	No	No	0	6	3
123	R:R:L186	R:R:L190	4.15	No	No	0	4	5
124	R:R:L192	R:R:P193	3.28	No	No	0	4	8
125	R:R:P193	R:R:Y225	9.74	No	No	0	8	5
126	R:R:H197	R:R:V196	5.54	No	No	0	5	4
127	R:R:H197	R:R:W215	21.16	No	Yes	0	5	5
128	L:L:D14	R:R:Y199	10.34	No	No	0	0	4
129	R:R:H200	R:R:R209	9.03	Yes	No	0	5	5
130	R:R:F214	R:R:V201	3.93	Yes	No	1	4	1
131	L:L:N16	R:R:V201	4.43	Yes	No	1	0	1
132	R:R:E202	R:R:R209	18.61	No	No	0	2	5
133	R:R:L203	R:R:V208	4.47	No	No	0	1	3
134	R:R:K204	R:R:P205	3.35	No	No	0	1	4
135	R:R:H206	R:R:V208	12.45	No	No	0	1	3
136	R:R:F214	R:R:L210	7.31	Yes	No	1	4	4
137	L:L:Y20	R:R:L210	8.21	Yes	No	1	0	4
138	R:R:E212	R:R:F214	12.83	No	Yes	1	4	4
139	L:L:Y20	R:R:E212	5.61	Yes	No	1	0	4
140	L:L:P27	R:R:E212	7.86	Yes	No	1	0	4
141	R:R:E213	R:R:W215	11.99	No	Yes	0	5	5
142	L:L:R30	R:R:E213	3.49	Yes	No	0	0	5
143	L:L:N16	R:R:F214	6.04	Yes	Yes	1	0	4
144	L:L:Y20	R:R:F214	8.25	Yes	Yes	1	0	4
145	R:R:Q218	R:R:W215	3.29	No	Yes	0	1	5
146	R:R:R222	R:R:W215	5	No	Yes	0	4	5
147	R:R:Q218	R:R:S217	8.66	No	No	0	1	3
148	R:R:Q218	R:R:Q221	12.8	No	No	0	1	4
149	R:R:E219	R:R:Q223	12.74	No	No	0	4	3
150	R:R:Q223	R:R:R222	4.67	No	No	0	3	4
151	R:R:L303	R:R:Q223	3.99	No	No	0	4	3
152	R:R:L229	R:R:Y225	18.76	No	No	3	4	5
153	L:L:R30	R:R:Y225	5.14	Yes	No	3	0	5
154	R:R:A226	R:R:D302	4.63	No	No	0	5	5
155	R:R:L299	R:R:W227	13.67	No	No	0	5	5
156	L:L:R30	R:R:L229	6.07	Yes	No	3	0	4
157	R:R:H295	R:R:T233	5.48	No	No	0	8	5
158	R:R:L235	R:R:Y234	3.52	No	Yes	0	4	8
159	R:R:L238	R:R:Y234	3.52	No	Yes	0	6	8
160	R:R:L292	R:R:Y234	9.38	No	Yes	0	5	8
161	R:R:H295	R:R:Y234	11.98	No	Yes	0	8	8
162	R:R:L236	R:R:P237	4.93	No	No	0	5	9
163	R:R:F287	R:R:L238	6.09	No	No	0	9	6
164	R:R:A288	R:R:L238	4.73	No	No	0	6	6
165	R:R:L280	R:R:Y245	7.03	Yes	Yes	0	7	9
166	R:R:I283	R:R:Y245	7.25	Yes	Yes	4	7	9
167	R:R:V284	R:R:Y245	5.05	No	Yes	0	7	9
168	R:R:F277	R:R:S249	3.96	No	No	0	6	5
169	R:R:L280	R:R:S249	6.01	Yes	No	0	7	5
170	R:R:L252	R:R:T276	4.42	No	No	0	8	7
171	R:R:R255	R:R:V257	3.92	No	No	6	6	4
172	R:R:D269	R:R:R255	4.76	No	No	6	4	6
173	R:R:R255	R:R:R273	8.53	No	No	6	6	7
174	R:R:P258	R:R:V257	3.53	No	No	0	4	4
175	R:R:D269	R:R:V257	4.38	No	No	6	4	4
176	R:R:S264	R:R:T262	3.2	No	No	0	4	3
177	R:R:Q265	R:R:T262	7.09	No	No	0	1	3
178	R:R:A266	R:R:R270	4.15	No	No	0	3	3
179	R:R:D267	R:R:R270	4.76	No	No	0	1	3
180	R:R:R272	R:R:W268	4	No	No	0	5	3
181	R:R:D269	R:R:R273	17.87	No	No	6	4	7
182	R:R:I283	R:R:I334	4.42	Yes	No	0	7	8
183	R:R:F287	R:R:W291	5.01	No	Yes	0	9	8
184	R:R:C290	R:R:S327	5.16	No	No	0	9	9
185	R:R:H295	R:R:W291	6.35	No	Yes	0	8	8
186	R:R:A324	R:R:W291	3.89	No	Yes	0	8	8
187	R:R:S327	R:R:W291	8.65	No	Yes	0	9	8
188	R:R:L292	R:R:P293	3.28	No	No	0	5	9
189	R:R:C320	R:R:P293	3.77	No	No	0	7	9
190	R:R:L323	R:R:P293	4.93	No	No	0	8	9
191	R:R:L294	R:R:N298	4.12	No	No	0	7	6
192	R:R:C320	R:R:L294	3.17	No	No	0	7	7
193	R:R:F297	R:R:F313	10.72	Yes	Yes	1	4	4
194	R:R:F297	R:R:V316	6.55	Yes	No	0	4	5
195	R:R:F297	R:R:Q317	7.03	Yes	No	0	4	4
196	L:L:R30	R:R:N298	6.03	Yes	No	0	0	6
197	R:R:D302	R:R:R301	3.57	No	No	0	5	4
198	L:L:P27	R:R:R301	12.97	Yes	No	0	0	4
199	L:L:R30	R:R:D302	9.53	Yes	No	0	0	5
200	R:R:D304	R:R:P305	4.83	No	No	0	3	3
201	R:R:A307	R:R:D304	4.63	No	No	0	2	3
202	L:L:R23	R:R:H306	18.05	No	No	0	0	2
203	R:R:D309	R:R:P310	6.44	No	No	0	1	3
204	R:R:D309	R:R:Y311	4.6	No	No	0	1	3
205	L:L:I25	R:R:F313	12.56	No	Yes	1	0	4
206	L:L:P27	R:R:F313	4.33	Yes	Yes	1	0	4
207	L:L:P27	R:R:Q317	3.16	Yes	No	0	0	4
208	L:L:V28	R:R:Q317	10.03	No	No	0	0	4
209	R:R:H321	R:R:M325	10.51	No	No	0	5	7
210	L:L:?33	R:R:H321	6.36	Yes	No	0	0	5
211	R:R:L323	R:R:W322	3.42	No	Yes	0	8	5
212	R:R:N331	R:R:Y335	4.65	Yes	Yes	4	9	9
213	R:R:F333	R:R:W337	4.01	No	Yes	0	6	7
214	R:R:I334	R:R:Y335	4.84	No	Yes	0	8	9
215	R:R:A336	R:R:W337	7.78	No	Yes	7	7	7
216	R:R:A336	R:R:F342	6.93	No	No	0	7	8
217	R:R:L346	R:R:W337	5.69	No	Yes	0	7	7
218	R:R:H339	R:R:L338	3.86	No	No	0	8	7
219	R:R:D340	R:R:R343	4.76	No	No	0	5	8
220	R:R:E344	R:R:K348	5.4	No	No	0	4	4
221	R:R:E345	R:R:L349	3.98	Yes	No	0	5	6
222	L:L:D14	L:L:I15	5.6	No	No	0	0	0
223	L:L:N16	L:L:P17	4.89	Yes	No	0	0	0
224	L:L:N16	L:L:Y20	8.14	Yes	Yes	1	0	0
225	L:L:S22	L:L:W19	6.18	No	No	0	0	0
226	L:L:R23	L:L:W19	4	No	No	0	0	0
227	L:L:I25	L:L:R23	8.77	No	No	0	0	0
228	L:L:I25	L:L:P27	5.08	No	Yes	1	0	0
229	L:L:F31	L:L:R30	3.21	Yes	Yes	3	0	0
230	L:L:?33	L:L:F31	6.03	Yes	Yes	3	0	0
231	R:R:E123	R:R:P124	3.14	Yes	No	0	4	4
232	R:R:A312	R:R:D309	3.09	No	No	0	4	1
233	R:R:I183	R:R:V147	3.07	No	Yes	0	7	7
234	R:R:I241	R:R:T153	3.04	No	No	0	8	7
235	R:R:L75	R:R:V71	2.98	No	No	0	6	7
236	R:R:L163	R:R:V248	2.98	No	No	0	8	8
237	R:R:L210	R:R:V208	2.98	No	No	0	4	3
238	R:R:L242	R:R:V284	2.98	No	No	0	4	7
239	R:R:L280	R:R:V248	2.98	Yes	No	0	7	8
240	R:R:L280	R:R:T276	2.95	Yes	No	0	7	7
241	R:R:I85	R:R:I99	2.94	No	No	0	7	8
242	R:R:P305	R:R:R222	2.88	No	No	0	3	4
243	R:R:Q54	R:R:V56	2.87	No	No	0	3	2
244	R:R:I155	R:R:L98	2.85	No	No	0	8	7
245	R:R:I308	R:R:L300	2.85	No	No	0	1	5
246	R:R:H206	R:R:S52	2.79	No	No	0	1	4
247	R:R:A121	R:R:F122	2.77	No	Yes	0	5	4
248	R:R:L230	R:R:L231	2.77	No	No	8	6	5
249	R:R:L230	R:R:L235	2.77	No	No	8	6	4
250	R:R:L231	R:R:L235	2.77	No	No	8	5	4
251	R:R:L299	R:R:L303	2.77	No	No	0	5	4
252	R:R:L55	R:R:Q58	2.66	No	No	0	3	2
253	R:R:F129	R:R:V128	2.62	Yes	No	2	7	3
254	R:R:D267	R:R:Q263	2.61	No	No	0	1	4
255	R:R:H339	R:R:L279	2.57	No	No	0	8	8
256	R:R:S244	R:R:Y245	2.54	No	Yes	0	8	9
257	R:R:V286	R:R:Y330	2.52	No	No	0	7	6
258	R:R:F122	R:R:I63	2.51	Yes	No	0	4	5
259	R:R:F297	R:R:I308	2.51	Yes	No	1	4	1
260	R:R:F313	R:R:I308	2.51	Yes	No	1	4	1
261	R:R:L349	R:R:R87	2.43	No	No	0	6	5
262	R:R:D207	R:R:R125	2.38	No	No	0	4	5
263	R:R:L108	R:R:W184	2.28	No	No	0	7	9
264	R:R:H339	R:R:R275	2.26	No	No	0	8	7
265	R:R:G131	R:R:G132	2.11	No	No	0	2	2
266	R:R:C329	R:R:G74	1.96	Yes	No	0	7	8
267	R:R:A103	R:R:G100	1.95	No	No	0	9	6
268	R:R:G314	R:R:V56	1.84	No	No	0	3	2
269	R:R:G61	R:R:V64	1.84	No	No	0	3	5
270	R:R:G100	R:R:V82	1.84	No	No	0	6	7
271	R:R:A328	R:R:C110	1.81	No	No	0	9	6
272	R:R:G61	R:R:K60	1.74	No	No	0	3	5
273	R:R:C290	R:R:S326	1.72	No	No	0	9	5
274	R:R:C329	R:R:S326	1.72	Yes	No	0	7	5
275	R:R:G77	R:R:L80	1.71	No	No	0	8	6
276	R:R:C290	R:R:V289	1.71	No	No	0	9	6
277	R:R:C134	R:R:T198	1.69	Yes	No	2	9	5
278	R:R:C211	R:R:T198	1.69	Yes	No	2	9	5
279	L:L:G24	R:R:Q54	1.64	No	No	0	0	3
280	R:R:E123	R:R:G126	1.64	Yes	No	0	4	5
281	R:R:S68	R:R:V69	1.62	No	No	0	5	4
282	R:R:A328	R:R:M109	1.61	No	Yes	0	9	8
283	R:R:V72	R:R:V73	1.6	No	No	0	6	5
284	R:R:V72	R:R:V76	1.6	No	No	0	6	5
285	R:R:V157	R:R:V240	1.6	No	No	0	6	7
286	R:R:V161	R:R:V162	1.6	No	No	0	5	8
287	R:R:V246	R:R:V250	1.6	No	No	0	3	3
288	R:R:V281	R:R:V285	1.6	No	No	0	5	4
289	R:R:V282	R:R:V286	1.6	No	No	0	6	7
290	R:R:C110	R:R:L75	1.59	No	No	0	6	6
291	R:R:I283	R:R:V282	1.54	Yes	No	0	7	6
292	R:R:I334	R:R:V286	1.54	No	No	0	8	7
293	R:R:H165	R:R:P166	1.53	No	No	0	6	8
294	R:R:A194	R:R:E213	1.51	No	No	0	4	5
295	R:R:L65	R:R:S68	1.5	No	No	0	6	5
296	R:R:L175	R:R:S172	1.5	No	No	0	4	4
297	L:L:G29	R:R:R301	1.5	No	No	0	0	4
298	R:R:L104	R:R:V107	1.49	No	No	0	6	7
299	R:R:L236	R:R:V240	1.49	No	No	0	5	7
300	R:R:L242	R:R:V246	1.49	No	No	0	4	3
301	R:R:N254	R:R:V250	1.48	No	No	0	4	3
302	R:R:I63	R:R:L315	1.43	No	No	0	5	1
303	R:R:A119	R:R:F129	1.39	No	Yes	0	5	7
304	R:R:L133	R:R:L136	1.38	No	No	0	6	4
305	R:R:D207	R:R:K204	1.38	No	No	0	4	1
306	R:R:R174	R:R:S172	1.32	No	No	0	6	4
307	R:R:R168	R:R:V161	1.31	No	No	0	4	5
308	R:R:V201	R:R:Y199	1.26	No	No	0	1	4
309	R:R:I171	R:R:R170	1.25	No	Yes	0	4	4
310	R:R:Q221	R:R:R220	1.17	No	No	0	4	4
311	R:R:E344	R:R:R347	1.16	No	No	0	4	5
312	R:R:R343	R:R:W337	1	No	Yes	0	8	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y67	6.296	5	0	8
2	R:R:L81	4.6375	4	7	9
3	R:R:L102	5.5925	4	4	9
4	R:R:D106	5.8275	4	4	9
5	R:R:M109	4.58	4	0	8
6	R:R:F122	4.0925	4	0	4
7	R:R:E123	3.1375	4	2	4
8	R:R:W127	4.96429	7	2	8
9	R:R:F129	3.5275	4	2	7
10	R:R:C134	5.492	5	2	9
11	R:R:Y146	6.05833	6	3	7
12	R:R:V147	5.8525	4	0	7
13	R:R:R170	6.29	4	0	4
14	R:R:H200	7.81	5	2	5
15	R:R:C211	5.6425	4	2	9
16	R:R:F214	7.672	5	1	4
17	R:R:W215	10.36	4	0	5
18	R:R:Y234	7.1	4	0	8
19	R:R:Y245	5.855	6	4	9
20	R:R:L280	4.7425	4	0	7
21	R:R:I283	4.2425	4	4	7
22	R:R:W291	5.975	4	0	8
23	R:R:F297	6.7025	4	1	4
24	R:R:F313	7.53	4	1	4
25	R:R:W322	6.9875	4	0	5
26	R:R:C329	3.48	4	0	7
27	R:R:N331	5.935	4	4	9
28	R:R:Y335	5.002	5	4	9
29	R:R:W337	4.97833	6	7	7
30	R:R:E345	5.6575	4	5	5
31	L:L:N16	5.875	4	1	0
32	L:L:Y20	7.5525	4	1	0
33	L:L:P27	6.68	5	1	0
34	L:L:R30	5.57833	6	3	0
35	L:L:F31	8.7025	4	3	0
36	L:L:?33	7.288	5	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:R26	R:R:L53	10.0409	3.64	No	No	0	0	3
2	L:L:R26	R:R:Y120	11.6238	5.14	No	No	0	0	5
3	L:L:V28	R:R:Y120	50.6386	5.05	No	No	0	0	5
4	L:L:V28	R:R:T117	55.6072	3.17	No	No	0	0	6
5	L:L:?33	R:R:T117	55.9738	3.65	Yes	No	3	0	6
6	L:L:?33	R:R:H321	42.3089	6.36	Yes	No	0	0	5
7	R:R:H321	R:R:Y67	39.901	9.8	No	Yes	0	5	8
8	R:R:L118	R:R:Y67	30.3367	7.03	No	Yes	0	7	8
9	R:R:F122	R:R:L118	28.3994	3.65	Yes	No	0	4	7
10	R:R:F122	R:R:I63	18.5296	2.51	Yes	No	0	4	5
11	R:R:I63	R:R:L315	16.519	1.43	No	No	0	5	1
12	R:R:L315	R:R:L59	14.4961	4.15	No	No	0	1	4
13	R:R:L59	R:R:Q58	12.461	5.32	No	No	0	4	2
14	R:R:L55	R:R:Q58	10.4137	2.66	No	No	0	3	2
15	R:R:W322	R:R:Y67	23.5287	4.82	Yes	Yes	0	5	8
16	R:R:V70	R:R:W322	14.7345	4.9	No	Yes	0	7	5
17	R:R:C329	R:R:V70	14.16	5.12	Yes	No	0	7	7
18	R:R:C329	R:R:V73	11.0799	5.12	Yes	No	0	7	5
19	R:R:A328	R:R:C110	11.031	1.81	No	No	0	9	6
20	R:R:A328	R:R:M109	12.8277	1.61	No	Yes	0	9	8
21	R:R:M109	R:R:V145	99.6883	6.09	Yes	No	0	8	7
22	L:L:F31	R:R:V145	94.2614	18.35	Yes	No	3	0	7
23	L:L:?33	L:L:F31	92.0858	6.03	Yes	Yes	3	0	0
24	R:R:A103	R:R:N78	43.9773	4.69	No	No	0	9	9
25	R:R:D106	R:R:N78	46.8618	6.73	Yes	No	0	9	9
26	R:R:D106	R:R:S148	100	4.42	Yes	No	0	9	9
27	R:R:M109	R:R:S148	94.4937	4.6	Yes	No	0	8	9
28	R:R:A103	R:R:L81	39.6871	3.15	No	Yes	0	9	9
29	R:R:L81	R:R:W337	11.3182	7.97	Yes	Yes	7	9	7
30	R:R:A336	R:R:L81	24.4393	3.15	No	Yes	7	7	9
31	R:R:L91	R:R:N96	19.813	6.87	No	No	0	7	8
32	R:R:F342	R:R:N96	24.9649	3.62	No	No	0	8	8
33	R:R:A336	R:R:F342	26.6699	6.93	No	No	0	7	8
34	R:R:D106	R:R:L102	26.7983	5.43	Yes	Yes	4	9	9
35	R:R:I155	R:R:L102	24.8671	4.28	No	Yes	0	8	9
36	R:R:I155	R:R:L98	30.0189	2.85	No	No	0	8	7
37	R:R:D158	R:R:L98	28.3444	4.07	No	No	0	8	7
38	R:R:D158	R:R:R170	26.6638	9.53	No	Yes	0	8	4
39	R:R:R170	R:R:V94	10.9882	9.15	Yes	No	0	4	6
40	R:R:D106	R:R:N331	54.556	6.73	Yes	Yes	4	9	9
41	L:L:F31	R:R:Y146	29.09	7.22	Yes	Yes	3	0	7
42	R:R:S187	R:R:Y146	19.7397	5.09	No	Yes	0	8	7
43	R:R:S187	R:R:V147	15.9262	3.23	No	Yes	0	8	7
44	R:R:L116	R:R:W127	32.9952	4.56	No	Yes	0	6	8
45	R:R:W127	R:R:Y120	40.1149	3.86	Yes	No	0	8	5
46	R:R:L116	R:R:V137	33.8385	8.94	No	No	0	6	6
47	R:R:F129	R:R:V128	23.217	2.62	Yes	No	2	7	3
48	R:R:F129	R:R:W127	28.7172	4.01	Yes	Yes	2	7	8
49	R:R:R125	R:R:V128	11.6299	5.23	No	No	2	5	3
50	R:R:H200	R:R:W127	17.3379	8.46	Yes	Yes	2	5	8
51	R:R:L229	R:R:Y146	15.3639	4.69	No	Yes	3	4	7
52	L:L:R30	R:R:L229	11.5138	6.07	Yes	No	3	0	4
53	L:L:F31	L:L:R30	63.4725	3.21	Yes	Yes	3	0	0
54	R:R:T233	R:R:Y146	23.5409	8.74	No	Yes	0	5	7
55	R:R:N331	R:R:Y335	49.6119	4.65	Yes	Yes	4	9	9
56	R:R:R159	R:R:Y335	53.8288	7.2	No	Yes	4	9	9
57	R:R:R159	R:R:Y245	48.6647	9.26	No	Yes	4	9	9
58	R:R:A156	R:R:Y245	15.7367	4	No	Yes	0	9	9
59	R:R:A156	R:R:I241	13.8116	3.25	No	No	0	9	8
60	R:R:I241	R:R:T153	11.8744	3.04	No	No	0	8	7
61	R:R:I183	R:R:V147	10.9332	3.07	No	Yes	0	7	7
62	R:R:F287	R:R:W291	10.0043	5.01	No	Yes	0	9	8
63	R:R:H295	R:R:W291	13.5	6.35	No	Yes	0	8	8
64	R:R:H295	R:R:T233	22.4042	5.48	No	No	0	8	5
65	R:R:F287	R:R:L152	20.1491	4.87	No	No	0	9	8
66	R:R:I334	R:R:Y335	10.8293	4.84	No	Yes	0	8	9
67	R:R:S244	R:R:Y245	11.8744	2.54	No	Yes	0	8	9
68	R:R:E213	R:R:W215	31.2229	11.99	No	Yes	0	5	5
69	L:L:R30	R:R:E213	34.7247	3.49	Yes	No	0	0	5
70	R:R:E212	R:R:F214	21.1147	12.83	No	Yes	1	4	4
71	L:L:P27	R:R:E212	36.6986	7.86	Yes	No	1	0	4
72	L:L:P27	R:R:Q317	14.4411	3.16	Yes	No	0	0	4
73	L:L:V28	R:R:Q317	20.3813	10.03	No	No	0	0	4
74	L:L:Y20	R:R:E212	14.0072	5.61	Yes	No	1	0	4
75	R:R:L210	R:R:V208	14.3433	2.98	No	No	0	4	3
76	R:R:R222	R:R:W215	17.9185	5	No	Yes	0	4	5
77	R:R:Q223	R:R:R222	10.1082	4.67	No	No	0	3	4
78	R:R:D302	R:R:R301	40.2371	3.57	No	No	0	5	4
79	L:L:P27	R:R:R301	38.1654	12.97	Yes	No	0	0	4
80	R:R:L238	R:R:Y234	12.9072	3.52	No	Yes	0	6	8
81	R:R:L292	R:R:Y234	10.3832	9.38	No	Yes	0	5	8
82	R:R:L292	R:R:P293	10.1448	3.28	No	No	0	5	9
83	R:R:L280	R:R:Y245	13.6405	7.03	Yes	Yes	0	7	9
84	R:R:Q141	R:R:V137	35.0364	4.3	No	No	0	6	6
85	L:L:?33	R:R:Q141	35.9347	16.47	Yes	No	3	0	6
86	R:R:F287	R:R:L238	11.2938	6.09	No	No	0	9	6
87	R:R:L152	R:R:Y335	15.2723	4.69	No	Yes	4	8	9
88	L:L:R30	R:R:D302	42.1866	9.53	Yes	No	0	0	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L53	R:R:Q54	5.32	0	No	No	3	3	1	1
R:R:H57	R:R:L53	12.86	0	No	No	4	3	2	1
L:L:R26	R:R:L53	3.64	0	No	No	0	3	0	1
R:R:H321	R:R:Y67	9.8	0	No	Yes	5	8	1	2
R:R:M109	R:R:V145	6.09	0	Yes	No	8	7	2	1
R:R:C113	R:R:M325	3.24	0	No	No	7	7	1	2
L:L:?33	R:R:C113	3.93	3	Yes	No	0	7	0	1
R:R:Q141	R:R:T117	4.25	3	No	No	6	6	1	1
L:L:V28	R:R:T117	3.17	0	No	No	0	6	0	1
L:L:?33	R:R:T117	3.65	3	Yes	No	0	6	0	1
R:R:W127	R:R:Y120	3.86	2	Yes	No	8	5	2	1
L:L:R26	R:R:Y120	5.14	0	No	No	0	5	0	1
L:L:V28	R:R:Y120	5.05	0	No	No	0	5	0	1
R:R:Q141	R:R:V137	4.3	3	No	No	6	6	1	2
L:L:?33	R:R:Q141	16.47	3	Yes	No	0	6	0	1
R:R:P142	R:R:Y146	5.56	0	No	Yes	5	7	2	1
R:R:V145	R:R:Y146	5.05	3	No	Yes	7	7	1	1
L:L:F31	R:R:V145	18.35	3	Yes	No	0	7	0	1
R:R:S187	R:R:Y146	5.09	0	No	Yes	8	7	2	1
R:R:L229	R:R:Y146	4.69	3	No	Yes	4	7	1	1
R:R:T233	R:R:Y146	8.74	0	No	Yes	5	7	2	1
L:L:F31	R:R:Y146	7.22	3	Yes	Yes	0	7	0	1
R:R:P193	R:R:Y225	9.74	0	No	No	8	5	2	1
L:L:D14	R:R:Y199	10.34	0	No	No	0	4	0	1
R:R:F214	R:R:V201	3.93	1	Yes	No	4	1	1	1
L:L:N16	R:R:V201	4.43	1	Yes	No	0	1	0	1
R:R:F214	R:R:L210	7.31	1	Yes	No	4	4	1	1
L:L:Y20	R:R:L210	8.21	1	Yes	No	0	4	0	1
R:R:E212	R:R:F214	12.83	1	No	Yes	4	4	1	1
L:L:Y20	R:R:E212	5.61	1	Yes	No	0	4	0	1
L:L:P27	R:R:E212	7.86	1	Yes	No	0	4	0	1
R:R:E213	R:R:W215	11.99	0	No	Yes	5	5	1	2
L:L:R30	R:R:E213	3.49	3	Yes	No	0	5	0	1
L:L:N16	R:R:F214	6.04	1	Yes	Yes	0	4	0	1
L:L:Y20	R:R:F214	8.25	1	Yes	Yes	0	4	0	1
R:R:L229	R:R:Y225	18.76	3	No	No	4	5	1	1
L:L:R30	R:R:Y225	5.14	3	Yes	No	0	5	0	1
R:R:A226	R:R:D302	4.63	0	No	No	5	5	2	1
L:L:R30	R:R:L229	6.07	3	Yes	No	0	4	0	1
R:R:L294	R:R:N298	4.12	0	No	No	7	6	2	1
R:R:F297	R:R:F313	10.72	1	Yes	Yes	4	4	2	1
R:R:F297	R:R:Q317	7.03	1	Yes	No	4	4	2	1
L:L:R30	R:R:N298	6.03	3	Yes	No	0	6	0	1
R:R:D302	R:R:R301	3.57	0	No	No	5	4	1	1
L:L:P27	R:R:R301	12.97	1	Yes	No	0	4	0	1
L:L:R30	R:R:D302	9.53	3	Yes	No	0	5	0	1
L:L:R23	R:R:H306	18.05	0	No	No	0	2	0	1
L:L:I25	R:R:F313	12.56	1	No	Yes	0	4	0	1
L:L:P27	R:R:F313	4.33	1	Yes	Yes	0	4	0	1
L:L:P27	R:R:Q317	3.16	1	Yes	No	0	4	0	1
L:L:V28	R:R:Q317	10.03	0	No	No	0	4	0	1
R:R:H321	R:R:M325	10.51	0	No	No	5	7	1	2
L:L:?33	R:R:H321	6.36	3	Yes	No	0	5	0	1
R:R:L210	R:R:V208	2.98	1	No	No	4	3	1	2
R:R:Q54	R:R:V56	2.87	0	No	No	3	2	1	2
R:R:F297	R:R:I308	2.51	1	Yes	No	4	1	2	2
R:R:F313	R:R:I308	2.51	1	Yes	No	4	1	1	2
L:L:G24	R:R:Q54	1.64	0	No	No	0	3	0	1
R:R:A194	R:R:E213	1.51	0	No	No	4	5	2	1
L:L:G29	R:R:R301	1.5	0	No	No	0	4	0	1
R:R:V201	R:R:Y199	1.26	1	No	No	1	4	1	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9K27_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.15
Number of Linked Nodes	284
Number of Links	312
Number of Hubs	36
Number of Links mediated by Hubs	140
Number of Communities	8
Number of Nodes involved in Communities	52
Number of Links involved in Communities	68

Path Summary
Number Of Nodes in MetaPath	89
Number Of Links MetaPath	88
Number of Shortest Paths	46181
Length Of Smallest Path	3
Average Path Length	13.0391
Length of Longest Path	29
Minimum Path Strength	1.41
Average Path Strength	5.88258
Maximum Path Strength	16.575
Minimum Path Correlation	0.7
Average Path Correlation	0.948215
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	63.9126
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.2712
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• reduction of food intake in response to dietary excess • multicellular organismal process • response to nutrient levels • response to stimulus • homeostatic process • eating behavior • feeding behavior • behavior • multicellular organismal-level homeostasis • response to dietary excess • energy homeostasis • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • developmental process • multicellular organism development • anatomical structure development • autonomic nervous system development • nervous system development • system development • response to insulin • fat cell differentiation • cellular developmental process • cell differentiation • cellular process • anatomical structure homeostasis • tissue homeostasis • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • biological regulation • G protein-coupled receptor signaling pathway • signal transduction • cell communication • primary metabolic process • metabolic process • lipid metabolic process • energy derivation by oxidation of organic compounds • energy reserve metabolic process • generation of precursor metabolites and energy • response to hexose • response to monosaccharide • response to carbohydrate • response to glucose • regulation of multicellular organism growth • regulation of growth • regulation of developmental growth • regulation of developmental process • developmental growth • growth • multicellular organism growth • regulation of multicellular organismal process • cellular anatomical structure • extracellular region • intracellular anatomical structure • cytoplasm • GTPase regulator activity • enzyme regulator activity • enzyme activator activity • GTPase activator activity • molecular function activator activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • protein binding • signaling receptor binding • G protein-coupled receptor binding • cation binding • metal ion binding • regulation of signaling • cell surface receptor signaling pathway • regulation of Wnt signaling pathway • regulation of canonical Wnt signaling pathway • canonical Wnt signaling pathway • regulation of signal transduction • regulation of response to stimulus • regulation of cell communication • Wnt signaling pathway • neuropeptide signaling pathway • regulation of body fluid levels • wound healing • hemostasis • blood coagulation • response to stress • coagulation • regulation of biological quality • response to wounding • regulation of protein stability • protein stabilization • phospholipase C-activating serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • phospholipase C-activating G protein-coupled receptor signaling pathway • rhythmic process • entrainment of circadian clock • circadian rhythm • response to external stimulus • regulation of circadian rhythm • hormone-mediated signaling pathway • cellular response to endogenous stimulus • cellular response to chemical stimulus • cellular response to hormone stimulus • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • glutamate receptor signaling pathway • system process • sensory perception • nervous system process • sensory perception of itch • adenylate cyclase-activating G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • establishment of organelle localization • regulated exocytosis • cellular localization • transport • cell activation involved in immune response • leukocyte degranulation • myeloid leukocyte activation • myeloid leukocyte mediated immunity • vesicle-mediated transport • leukocyte activation • localization • secretion by cell • organelle localization • leukocyte activation involved in immune response • establishment of localization in cell • mast cell activation • leukocyte mediated immunity • mast cell mediated immunity • immune response • secretion • cell activation • vacuolar localization • export from cell • mast cell degranulation • establishment of localization • myeloid cell activation involved in immune response • immune effector process • mast cell activation involved in immune response • exocytosis • immune system process • lysosome localization • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • detection of light stimulus • response to light stimulus • phototransduction • detection of external stimulus • detection of visible light • detection of abiotic stimulus • detection of stimulus • response to radiation • phototransduction, visible light • regulation of cell activation • regulation of platelet activation • platelet activation • phospholipase C-activating G protein-coupled glutamate receptor signaling pathway • G protein-coupled glutamate receptor signaling pathway • cellular response to nitrogen compound • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • cellular response to oxygen-containing compound • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • membrane-bounded organelle • nuclear membrane • nucleus • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • organelle envelope • organelle • nuclear envelope • organelle membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • Golgi apparatus • postsynapse • synapse • cell junction • postsynaptic cytosol • cytosol • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • cellular response to ketone • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • photoreceptor disc membrane • neuropeptide binding • peptide binding • peptide receptor activity • molecular transducer activity • neuropeptide Y receptor activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • neuropeptide receptor activity • multi-multicellular organism process • reproductive process • female pregnancy • multi-organism reproductive process • regulation of hormone levels • hormone metabolic process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?33
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P49683
Sequence	>9K27_nogp_Chain_R S L Q L V H Q L K G L I V L L Y S V V V V V G L V G N C L L V L V I A R V R R L H N V T N F L I G N L A L S D V L M C T A C V P L T L A Y A F E P R G W V F G G G L C H L V F F L Q P V T V Y V S V F T L T T I A V D R Y V V L V H P L R R R I S L R L S A Y A V L A I W A L S A V L A L P A A V H T Y H V E L K P H D V R L C E E F W G S Q E R Q R Q L Y A W G L L L V T Y L L P L L V I L L S Y V R V S V K L R N R V V P G C V T Q S Q A D W D R A R R R R T F C L L V V I V V V F A V C W L P L H V F N L L R D L D P H A I D P Y A F G L V Q L L C H W L A M S S A C Y N P F I Y A W L H D S F R E E L R K L L V A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	L
Protein	PrRP31
UniProt	P81277
Sequence	>9K27_nogp_Chain_L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZPS	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP20	-	chim(NtGi1-Gs-CtGi1)/β1/γ2	2.97	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPS (No Gprot)	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP20	-		2.97	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPT	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP20	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.96	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	8ZPT (No Gprot)	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP20	-		2.96	2024-09-25	doi.org/10.1038/s41421-024-00724-6
	9K26	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP31	-	Gi1/β1/γ2	3	2025-01-29	To be published
	9K26 (No Gprot)	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP31	-		3	2025-01-29	To be published
	9K27	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP31	-	chim(NtGi1-Gq)/β1/γ2	2.68	2025-01-29	To be published
	9K27 (No Gprot)	A	Peptide	Prolactin-Releasing Peptide	PrRP	Homo sapiens	PrRP31	-		2.68	2025-01-29	To be published

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Download 9K27_nogp.zip

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