psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:C160	R:R:C5	7.28	No	No	0	1	8
2	R:R:I6	R:R:Q9	12.35	No	No	0	5	3
3	R:R:H261	R:R:I6	5.3	No	No	0	4	5
4	R:R:I6	R:R:K266	7.27	No	No	0	5	3
5	R:R:E7	R:R:E8	3.81	No	No	0	4	3
6	R:R:D11	R:R:E7	6.5	No	No	0	5	4
7	R:R:E8	R:R:K266	8.1	No	No	0	3	3
8	R:R:Q9	R:R:Y269	10.15	No	No	0	3	4
9	R:R:H10	R:R:N76	15.31	No	No	0	5	4
10	R:R:F167	R:R:H10	3.39	Yes	No	0	3	5
11	R:R:D13	R:R:L12	4.07	No	No	0	4	6
12	R:R:L12	R:R:T270	4.42	No	No	0	6	2
13	R:R:D13	R:R:F17	9.55	No	Yes	3	4	6
14	R:R:D13	R:R:R273	11.91	No	No	3	4	4
15	R:R:H14	R:R:W75	17.98	No	No	0	6	4
16	R:R:I274	R:R:L16	4.28	No	No	0	5	6
17	R:R:F17	R:R:Y21	11.35	Yes	Yes	0	6	8
18	R:R:F17	R:R:T74	11.67	Yes	No	0	6	5
19	R:R:F17	R:R:R273	18.17	Yes	No	3	6	4
20	R:R:A277	R:R:F17	4.16	No	Yes	0	6	6
21	R:R:I71	R:R:P18	5.08	No	No	0	7	5
22	R:R:P18	R:R:T74	3.5	No	No	0	5	5
23	R:R:V20	R:R:Y21	3.79	No	Yes	0	4	8
24	R:R:L67	R:R:Y21	8.21	No	Yes	0	8	8
25	R:R:I71	R:R:Y21	3.63	No	Yes	0	7	8
26	R:R:S280	R:R:Y21	5.09	No	Yes	0	7	8
27	R:R:F23	R:R:V27	9.18	No	No	0	5	7
28	R:R:S280	R:R:V24	9.7	No	No	0	7	7
29	R:R:I25	R:R:I29	4.42	No	No	0	7	5
30	R:R:I25	R:R:P68	3.39	No	No	0	7	9
31	R:R:I26	R:R:V27	4.61	No	No	0	6	7
32	R:R:V27	R:R:V284	4.81	No	No	0	7	7
33	R:R:C283	R:R:S28	3.44	No	No	0	8	8
34	R:R:S28	R:R:V284	4.85	No	No	0	8	7
35	R:R:I29	R:R:P30	6.77	No	No	0	5	5
36	R:R:A64	R:R:I29	3.25	No	No	0	5	5
37	R:R:A31	R:R:P287	3.74	No	No	0	7	9
38	R:R:D60	R:R:N32	8.08	Yes	No	0	9	9
39	R:R:L61	R:R:N32	4.12	No	No	0	8	9
40	R:R:N32	R:R:P287	8.15	No	No	0	9	9
41	R:R:I33	R:R:L61	4.28	No	No	0	4	8
42	R:R:S35	R:R:S57	3.26	No	No	0	8	8
43	R:R:P287	R:R:S35	5.34	No	No	0	9	8
44	R:R:F54	R:R:L36	9.74	No	No	0	6	7
45	R:R:L36	R:R:S57	6.01	No	No	0	7	8
46	R:R:C37	R:R:M301	6.48	No	Yes	0	3	5
47	R:R:C291	R:R:V38	3.42	No	No	0	7	7
48	R:R:M301	R:R:V38	6.09	Yes	No	0	5	7
49	R:R:L53	R:R:S39	6.01	Yes	No	0	8	7
50	R:R:F40	R:R:K44	11.17	No	No	0	3	6
51	R:R:Q42	R:R:S47	8.66	No	No	0	5	8
52	R:R:G50	R:R:Q42	3.29	No	No	0	7	5
53	R:R:D111	R:R:E48	11.69	No	No	0	8	6
54	R:R:E48	R:R:R126	5.82	No	No	0	6	6
55	R:R:L49	R:R:L53	4.15	No	Yes	0	8	8
56	R:R:D111	R:R:L49	6.79	No	No	0	8	8
57	R:R:L49	R:R:R112	3.64	No	No	0	8	9
58	R:R:G50	R:R:L53	3.42	No	Yes	0	7	8
59	R:R:I51	R:R:R128	6.26	No	No	4	7	2
60	R:R:A131	R:R:I51	4.87	No	No	0	8	7
61	R:R:I51	R:R:L132	4.28	No	No	4	7	3
62	R:R:C107	R:R:Y52	9.41	No	Yes	0	7	7
63	R:R:D111	R:R:Y52	6.9	No	Yes	0	8	7
64	R:R:A131	R:R:Y52	5.34	No	Yes	0	8	7
65	R:R:I108	R:R:L53	5.71	No	Yes	0	9	8
66	R:R:F104	R:R:S55	17.18	No	No	0	7	9
67	R:R:D60	R:R:L56	5.43	Yes	No	0	9	9
68	R:R:L105	R:R:L56	6.92	No	No	0	9	9
69	R:R:N97	R:R:S59	8.94	No	No	5	8	8
70	R:R:S100	R:R:S59	3.26	No	No	0	7	8
71	R:R:S101	R:R:S59	6.52	No	No	5	9	8
72	R:R:D60	R:R:S101	4.42	Yes	No	0	9	9
73	R:R:D286	R:R:D60	3.99	No	Yes	0	9	9
74	R:R:L62	R:R:L93	9.69	No	No	0	7	5
75	R:R:L67	R:R:Y63	9.38	No	Yes	0	8	7
76	R:R:M94	R:R:Y63	8.38	No	Yes	0	7	7
77	R:R:N97	R:R:Y63	13.96	No	Yes	0	8	7
78	R:R:C283	R:R:Y63	5.38	No	Yes	0	8	7
79	R:R:L93	R:R:T66	4.42	No	Yes	0	5	7
80	R:R:M94	R:R:T66	4.52	No	Yes	0	7	7
81	R:R:L69	R:R:S90	6.01	No	No	0	7	5
82	R:R:W70	R:R:Y73	3.86	No	No	0	7	5
83	R:R:S90	R:R:W70	3.71	No	No	0	5	7
84	R:R:C170	R:R:W70	3.92	No	No	0	9	7
85	R:R:F167	R:R:Y73	8.25	Yes	No	0	3	5
86	R:R:F82	R:R:W80	14.03	No	No	0	8	9
87	R:R:T168	R:R:W80	3.64	No	No	0	5	9
88	R:R:F82	R:R:L86	6.09	No	No	0	8	6
89	R:R:K88	R:R:P84	3.35	No	No	0	7	2
90	R:R:P84	R:R:T155	3.5	No	No	0	2	5
91	R:R:C87	R:R:T155	3.38	No	No	0	9	5
92	R:R:C170	R:R:C87	7.28	No	No	0	9	9
93	R:R:A91	R:R:Y171	4	No	Yes	0	5	3
94	R:R:F92	R:R:N146	13.29	No	No	0	6	7
95	R:R:F92	R:R:M149	3.73	No	No	0	6	4
96	R:R:F92	R:R:L150	17.05	No	No	0	6	5
97	R:R:M94	R:R:Y95	9.58	No	Yes	0	7	5
98	R:R:Y95	R:R:Y99	8.94	Yes	Yes	1	5	7
99	R:R:Y171	R:R:Y95	15.89	Yes	Yes	1	3	5
100	R:R:R187	R:R:Y95	22.64	Yes	Yes	1	5	5
101	R:R:M96	R:R:W139	5.82	No	Yes	0	5	9
102	R:R:E142	R:R:M96	12.18	Yes	No	6	8	5
103	R:R:M96	R:R:T143	4.52	No	No	6	5	4
104	R:R:N97	R:R:S101	5.96	No	No	5	8	9
105	R:R:F98	R:R:Y99	9.28	Yes	Yes	1	8	7
106	R:R:F239	R:R:F98	7.5	Yes	Yes	0	9	8
107	R:R:F242	R:R:F98	7.5	Yes	Yes	1	7	8
108	R:R:F98	R:R:H243	7.92	Yes	Yes	1	8	8
109	R:R:F98	R:R:T279	5.19	Yes	No	1	8	8
110	R:R:R187	R:R:Y99	16.46	Yes	Yes	1	5	7
111	R:R:S100	R:R:W139	6.18	No	Yes	0	7	9
112	R:R:E142	R:R:S100	4.31	Yes	No	0	8	7
113	R:R:P195	R:R:T102	5.25	No	No	0	9	8
114	R:R:F239	R:R:T102	3.89	Yes	No	0	9	8
115	R:R:A103	R:R:I138	3.25	No	No	0	6	7
116	R:R:F104	R:R:W139	7.02	No	Yes	0	7	9
117	R:R:D286	R:R:L105	5.43	No	No	0	9	9
118	R:R:L105	R:R:Y290	3.52	No	No	0	9	9
119	R:R:P195	R:R:T106	8.74	No	No	0	9	8
120	R:R:T106	R:R:T198	4.71	No	No	0	8	6
121	R:R:A109	R:R:I199	3.25	No	No	0	9	8
122	R:R:A109	R:R:C202	3.61	No	No	0	9	7
123	R:R:C202	R:R:V110	3.42	No	No	0	7	6
124	R:R:R112	R:R:Y290	5.14	No	No	0	9	9
125	R:R:L114	R:R:Y113	4.69	No	Yes	0	6	8
126	R:R:V117	R:R:Y113	12.62	No	Yes	2	7	8
127	R:R:Y113	R:R:Y118	6.95	Yes	Yes	2	8	6
128	R:R:C202	R:R:Y113	4.03	No	Yes	0	7	8
129	R:R:K205	R:R:Y113	7.17	No	Yes	0	4	8
130	R:R:V117	R:R:Y118	7.57	No	Yes	2	7	6
131	R:R:K121	R:R:Y118	5.97	No	Yes	2	5	6
132	R:R:F122	R:R:Y118	9.28	No	Yes	2	5	6
133	R:R:L120	R:R:P119	3.28	No	No	0	6	9
134	R:R:F122	R:R:K121	6.2	No	No	2	5	5
135	R:R:F124	R:R:L125	6.09	No	No	0	5	3
136	R:R:F130	R:R:L125	6.09	Yes	No	0	3	3
137	R:R:L132	R:R:R128	4.86	No	No	4	3	2
138	R:R:F130	R:R:V134	6.55	Yes	No	0	3	6
139	R:R:F145	R:R:L141	6.09	No	No	0	5	5
140	R:R:E142	R:R:T143	7.06	Yes	No	6	8	4
141	R:R:E142	R:R:N146	9.2	Yes	No	0	8	7
142	R:R:F145	R:R:I144	6.28	No	No	0	5	4
143	R:R:F145	R:R:F186	9.65	No	No	0	5	3
144	R:R:L183	R:R:V148	5.96	No	No	0	5	7
145	R:R:E152	R:R:W179	16.36	No	Yes	0	5	3
146	R:R:E154	R:R:Y171	10.1	No	Yes	1	4	3
147	R:R:E154	R:R:W179	16.36	No	Yes	1	4	3
148	R:R:E154	R:R:Q180	10.19	No	Yes	1	4	3
149	R:R:K173	R:R:V156	6.07	No	No	0	4	2
150	R:R:E158	R:R:L169	5.3	No	No	0	2	3
151	R:R:N166	R:R:Y159	6.98	No	No	0	4	1
152	R:R:E163	R:R:S165	11.5	No	No	0	1	4
153	R:R:D172	R:R:Y171	9.2	No	Yes	0	5	3
154	R:R:R187	R:R:Y171	4.12	Yes	Yes	1	5	3
155	R:R:E177	R:R:K173	5.4	No	No	1	2	4
156	R:R:K173	R:R:Q180	5.42	No	Yes	1	4	3
157	R:R:E253	R:R:Y174	3.37	Yes	No	1	4	5
158	R:R:S264	R:R:Y174	5.09	No	No	1	3	5
159	R:R:G265	R:R:Y174	5.79	No	No	1	1	5
160	R:R:E253	R:R:P175	6.29	Yes	No	0	4	3
161	R:R:F258	R:R:P175	13	No	No	0	2	3
162	R:R:L176	R:R:Q180	5.32	Yes	Yes	1	1	3
163	R:R:I181	R:R:L176	4.28	Yes	Yes	0	3	1
164	R:R:L176	R:R:R249	8.5	Yes	Yes	1	1	4
165	R:R:E253	R:R:L176	11.93	Yes	Yes	1	4	1
166	R:R:E177	R:R:W179	4.36	No	Yes	1	2	3
167	R:R:E177	R:R:Q180	6.37	No	Yes	1	2	3
168	R:R:Q180	R:R:W179	14.24	Yes	Yes	1	3	3
169	R:R:C250	R:R:I181	3.27	No	Yes	0	5	3
170	R:R:L183	R:R:R187	18.22	No	Yes	0	5	5
171	R:R:N184	R:R:R187	6.03	No	Yes	0	5	5
172	R:R:L246	R:R:N184	5.49	No	No	0	6	5
173	R:R:C250	R:R:L185	4.76	No	No	0	5	4
174	R:R:F186	R:R:T190	10.38	No	No	0	3	4
175	R:R:L247	R:R:T188	5.9	No	No	0	6	6
176	R:R:G191	R:R:T190	3.64	No	No	0	5	4
177	R:R:L196	R:R:Y192	3.52	No	No	0	7	9
178	R:R:T240	R:R:Y192	4.99	No	No	0	5	9
179	R:R:H243	R:R:Y192	27.22	Yes	No	0	8	9
180	R:R:I194	R:R:P195	3.39	No	No	0	6	9
181	R:R:L196	R:R:L200	4.15	No	No	0	7	5
182	R:R:F235	R:R:L196	3.65	No	No	0	9	7
183	R:R:F235	R:R:I199	3.77	No	No	0	9	8
184	R:R:N203	R:R:T232	4.39	Yes	No	0	9	8
185	R:R:R204	R:R:Y207	6.17	No	Yes	0	3	5
186	R:R:R211	R:R:Y207	13.38	No	Yes	0	4	5
187	R:R:I225	R:R:Y207	4.84	No	Yes	0	6	5
188	R:R:I224	R:R:V210	12.29	No	No	0	7	8
189	R:R:N213	R:R:T216	8.77	No	No	0	5	2
190	R:R:K221	R:R:T216	6.01	No	No	0	6	2
191	R:R:E217	R:R:E220	3.81	No	No	0	3	5
192	R:R:E220	R:R:K219	6.75	No	No	0	5	4
193	R:R:L227	R:R:V293	4.47	No	No	0	8	7
194	R:R:L289	R:R:S230	7.51	No	No	0	8	5
195	R:R:I231	R:R:L289	4.28	No	No	0	8	8
196	R:R:I231	R:R:Y290	4.84	No	No	0	8	9
197	R:R:A285	R:R:T234	3.36	No	No	0	7	6
198	R:R:L289	R:R:T234	5.9	No	No	0	8	6
199	R:R:F235	R:R:F239	7.5	No	Yes	0	9	9
200	R:R:T240	R:R:V236	4.76	No	No	0	5	5
201	R:R:F239	R:R:N282	10.87	Yes	No	0	9	9
202	R:R:P241	R:R:T240	5.25	No	No	0	9	5
203	R:R:P241	R:R:T275	3.5	No	No	0	9	7
204	R:R:L278	R:R:P241	3.28	No	No	0	8	9
205	R:R:F242	R:R:H243	6.79	Yes	Yes	1	7	8
206	R:R:F242	R:R:L246	4.87	Yes	No	1	7	6
207	R:R:F242	R:R:Y272	9.28	Yes	Yes	1	7	4
208	R:R:F242	R:R:V276	6.55	Yes	No	1	7	6
209	R:R:F242	R:R:T279	5.19	Yes	No	1	7	8
210	R:R:M245	R:R:Y272	4.79	Yes	Yes	0	5	4
211	R:R:M245	R:R:T275	4.52	Yes	No	0	5	7
212	R:R:L246	R:R:Y272	9.38	No	Yes	1	6	4
213	R:R:E253	R:R:R249	16.28	Yes	Yes	1	4	4
214	R:R:R249	R:R:Y269	4.12	Yes	No	0	4	4
215	R:R:R249	R:R:Y272	14.4	Yes	Yes	1	4	4
216	R:R:I251	R:R:L252	4.28	No	No	0	5	3
217	R:R:L252	R:R:V256	5.96	No	No	0	3	1
218	R:R:E259	R:R:N257	3.94	No	No	0	1	2
219	R:R:N263	R:R:S262	4.47	No	No	0	3	8
220	R:R:N263	R:R:R267	4.82	No	No	0	3	4
221	R:R:G265	R:R:S264	3.71	No	No	1	1	3
222	R:R:R273	R:R:Y269	12.35	No	No	0	4	4
223	R:R:V276	R:R:Y272	6.31	No	Yes	1	6	4
224	R:R:D286	R:R:N282	14.81	No	No	0	9	9
225	R:R:C291	R:R:F292	5.59	No	No	0	7	7
226	R:R:E295	R:R:G297	4.91	No	No	0	5	8
227	R:R:M301	R:R:R298	6.2	Yes	No	0	5	8
228	R:R:R298	R:R:W302	13	No	No	0	8	4
229	R:R:N303	R:R:Y299	15.12	No	No	0	5	4
230	R:R:D300	R:R:I304	5.6	No	No	0	4	4
231	R:R:L305	R:R:M301	4.24	No	Yes	0	6	5
232	R:R:S137	R:R:V134	3.23	No	No	0	4	6
233	R:R:F40	R:R:F54	3.22	No	No	0	3	6
234	R:R:S90	R:R:T66	3.2	No	Yes	0	5	7
235	R:R:S264	R:R:T268	3.2	No	No	0	3	4
236	R:R:T168	R:R:V157	3.17	No	No	0	5	1
237	R:R:T294	R:R:V293	3.17	No	No	0	8	7
238	R:R:A277	R:R:L16	3.15	No	No	0	6	6
239	R:R:C238	R:R:N282	3.15	No	No	0	8	9
240	R:R:C160	R:R:E163	3.04	No	No	0	1	1
241	R:R:L86	R:R:S83	3	No	No	0	6	8
242	R:R:L281	R:R:V24	2.98	No	No	0	5	7
243	R:R:L237	R:R:V233	2.98	No	No	0	6	5
244	R:R:C5	R:R:H10	2.95	No	No	0	8	5
245	R:R:L65	R:R:T66	2.95	No	Yes	0	5	7
246	R:R:I22	R:R:I71	2.94	No	No	0	5	7
247	R:R:I25	R:R:I26	2.94	No	No	0	7	6
248	R:R:I248	R:R:M245	2.92	No	Yes	0	4	5
249	R:R:I201	R:R:K205	2.91	No	No	0	5	4
250	R:R:G191	R:R:Y99	2.9	No	Yes	0	5	7
251	R:R:M245	R:R:M271	2.89	Yes	No	0	5	6
252	R:R:W302	R:R:Y299	2.89	No	No	0	4	4
253	R:R:I224	R:R:L228	2.85	No	Yes	0	7	8
254	R:R:I248	R:R:L252	2.85	No	No	0	4	3
255	R:R:E220	R:R:T216	2.82	No	No	0	5	2
256	R:R:A31	R:R:F292	2.77	No	No	0	7	7
257	R:R:L228	R:R:N203	2.75	Yes	Yes	0	8	9
258	R:R:H243	R:R:T188	2.74	Yes	No	0	8	6
259	R:R:F82	R:R:T81	2.59	No	No	0	8	3
260	R:R:F167	R:R:T168	2.59	Yes	No	0	3	5
261	R:R:S135	R:R:Y52	2.54	No	Yes	0	7	7
262	R:R:F104	R:R:I138	2.51	No	No	0	7	7
263	R:R:M271	R:R:R267	2.48	No	No	0	6	4
264	R:R:F167	R:R:L169	2.44	Yes	No	0	3	3
265	R:R:K77	R:R:W75	2.32	No	No	0	4	4
266	R:R:D161	R:R:Y159	2.3	No	No	0	4	1
267	R:R:L58	R:R:W139	2.28	No	Yes	0	6	9
268	R:R:H14	R:R:Y15	2.18	No	No	0	6	3
269	R:R:C37	R:R:G34	1.96	No	No	0	3	6
270	R:R:A43	R:R:G50	1.95	No	No	0	6	7
271	R:R:G297	R:R:T296	1.82	No	No	0	8	7
272	R:R:G89	R:R:K88	1.74	No	No	0	5	7
273	R:R:A85	R:R:S83	1.71	No	No	0	2	8
274	R:R:C107	R:R:V134	1.71	No	No	0	7	6
275	R:R:A209	R:R:V116	1.7	No	No	0	5	8
276	R:R:C189	R:R:T190	1.69	No	No	0	4	4
277	R:R:D300	R:R:G297	1.68	No	No	0	4	8
278	R:R:V229	R:R:V233	1.6	No	No	0	4	5
279	R:R:T198	R:R:V197	1.59	No	No	0	6	4
280	R:R:T232	R:R:V233	1.59	No	No	0	8	5
281	R:R:A147	R:R:L150	1.58	No	No	0	4	5
282	R:R:A215	R:R:N213	1.56	No	No	0	1	5
283	R:R:I288	R:R:V284	1.54	No	No	0	7	7
284	R:R:I288	R:R:V293	1.54	No	No	0	7	7
285	R:R:L228	R:R:V206	1.49	Yes	No	0	8	8
286	R:R:N166	R:R:V157	1.48	No	No	0	4	1
287	R:R:I140	R:R:I144	1.47	No	No	0	4	4
288	R:R:I304	R:R:L41	1.43	No	No	0	4	4
289	R:R:I304	R:R:L305	1.43	No	No	0	4	6
290	R:R:I181	R:R:N182	1.42	Yes	No	0	3	4
291	R:R:I199	R:R:N203	1.42	No	Yes	0	8	9
292	R:R:I231	R:R:N203	1.42	No	Yes	0	8	9
293	R:R:K45	R:R:L41	1.41	No	No	0	6	4
294	R:R:K178	R:R:N182	1.4	No	No	0	3	4
295	R:R:K219	R:R:N218	1.4	No	No	0	4	3
296	R:R:P119	R:R:Y118	1.39	No	Yes	0	9	6
297	R:R:A115	R:R:R126	1.38	No	No	0	8	6
298	R:R:P18	R:R:W75	1.35	No	No	0	5	4
299	R:R:H254	R:R:I181	1.33	No	Yes	0	1	3
300	R:R:F130	R:R:T127	1.3	Yes	No	0	3	6
301	R:R:D153	R:R:E152	1.3	No	No	0	5	5
302	R:R:F130	R:R:M133	1.24	Yes	No	0	3	3
303	R:R:K219	R:R:R223	1.24	No	No	0	4	7
304	R:R:K164	R:R:Y159	1.19	No	No	0	1	1
305	R:R:E46	R:R:F123	1.17	No	No	0	6	5
306	R:R:L228	R:R:Y207	1.17	Yes	Yes	0	8	5
307	R:R:E259	R:R:F258	1.17	No	No	0	1	2
308	R:R:R128	R:R:R129	1.07	No	No	0	2	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F17	10.98	5	3	6
2	R:R:Y21	6.414	5	0	8
3	R:R:Y52	6.0475	4	0	7
4	R:R:L53	4.8225	4	0	8
5	R:R:D60	5.48	4	0	9
6	R:R:Y63	9.275	4	0	7
7	R:R:T66	3.7725	4	0	7
8	R:R:Y95	14.2625	4	1	5
9	R:R:F98	7.478	5	1	8
10	R:R:Y99	9.395	4	1	7
11	R:R:Y113	7.092	5	2	8
12	R:R:Y118	6.232	5	2	6
13	R:R:F130	3.795	4	0	3
14	R:R:W139	5.325	4	0	9
15	R:R:E142	8.1875	4	6	8
16	R:R:F167	4.1675	4	0	3
17	R:R:Y171	8.662	5	1	3
18	R:R:L176	7.5075	4	1	1
19	R:R:W179	12.83	4	1	3
20	R:R:Q180	8.308	5	1	3
21	R:R:I181	2.575	4	0	3
22	R:R:R187	13.494	5	1	5
23	R:R:N203	2.495	4	0	9
24	R:R:Y207	6.39	4	0	5
25	R:R:L228	2.065	4	0	8
26	R:R:F239	7.44	4	0	9
27	R:R:F242	6.69667	6	1	7
28	R:R:H243	11.1675	4	1	8
29	R:R:M245	3.78	4	0	5
30	R:R:R249	10.825	4	1	4
31	R:R:E253	9.4675	4	1	4
32	R:R:Y272	8.832	5	1	4
33	R:R:M301	5.7525	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F167	R:R:H10	14.3837	3.39	Yes	No	0	3	5
2	R:R:F167	R:R:Y73	48.4357	8.25	Yes	No	0	3	5
3	R:R:W70	R:R:Y73	50.6069	3.86	No	No	0	7	5
4	R:R:S90	R:R:W70	65.1338	3.71	No	No	0	5	7
5	R:R:S90	R:R:T66	69.1896	3.2	No	Yes	0	5	7
6	R:R:M94	R:R:T66	77.1202	4.52	No	Yes	0	7	7
7	R:R:M94	R:R:Y63	80.8594	8.38	No	Yes	0	7	7
8	R:R:L67	R:R:Y63	47.1014	9.38	No	Yes	0	8	7
9	R:R:L67	R:R:Y21	45.4504	8.21	No	Yes	0	8	8
10	R:R:F17	R:R:Y21	25.1263	11.35	Yes	Yes	0	6	8
11	R:R:F17	R:R:R273	20.6936	18.17	Yes	No	3	6	4
12	R:R:R273	R:R:Y269	23.121	12.35	No	No	0	4	4
13	R:R:Q9	R:R:Y269	15.7331	10.15	No	No	0	3	4
14	R:R:I6	R:R:Q9	13.6826	12.35	No	No	0	5	3
15	R:R:I71	R:R:Y21	14.9868	3.63	No	Yes	0	7	8
16	R:R:P18	R:R:W75	11.1496	1.35	No	No	0	5	4
17	R:R:C283	R:R:Y63	38.4847	5.38	No	Yes	0	8	7
18	R:R:C283	R:R:S28	36.0121	3.44	No	No	0	8	8
19	R:R:S28	R:R:V284	33.5243	4.85	No	No	0	8	7
20	R:R:V27	R:R:V284	21.0403	4.81	No	No	0	7	7
21	R:R:I26	R:R:V27	15.8688	4.61	No	No	0	6	7
22	R:R:I25	R:R:I26	13.2605	2.94	No	No	0	7	6
23	R:R:A31	R:R:P287	45.5937	3.74	No	No	0	7	9
24	R:R:N32	R:R:P287	61.161	8.15	No	No	0	9	9
25	R:R:D60	R:R:N32	67.6065	8.08	Yes	No	0	9	9
26	R:R:D60	R:R:S101	94.3008	4.42	Yes	No	0	9	9
27	R:R:N97	R:R:S101	70.5465	5.96	No	No	5	8	9
28	R:R:N97	R:R:Y63	92.3106	13.96	No	Yes	0	8	7
29	R:R:P287	R:R:S35	15.0999	5.34	No	No	0	9	8
30	R:R:S35	R:R:S57	12.6197	3.26	No	No	0	8	8
31	R:R:L36	R:R:S57	10.1244	6.01	No	No	0	7	8
32	R:R:A31	R:R:F292	43.2944	2.77	No	No	0	7	7
33	R:R:C291	R:R:F292	40.9951	5.59	No	No	0	7	7
34	R:R:C291	R:R:V38	38.6732	3.42	No	No	0	7	7
35	R:R:M301	R:R:V38	36.5247	6.09	Yes	No	0	5	7
36	R:R:D60	R:R:L56	41.5077	5.43	Yes	No	0	9	9
37	R:R:L105	R:R:L56	40.8594	6.92	No	No	0	9	9
38	R:R:L105	R:R:Y290	100	3.52	No	No	0	9	9
39	R:R:R112	R:R:Y290	81.1609	5.14	No	No	0	9	9
40	R:R:L49	R:R:R112	78.6506	3.64	No	No	0	8	9
41	R:R:L49	R:R:L53	21.5153	4.15	No	Yes	0	8	8
42	R:R:D286	R:R:D60	70.6973	3.99	No	Yes	0	9	9
43	R:R:D286	R:R:L105	62.6461	5.43	No	No	0	9	9
44	R:R:G50	R:R:L53	12.4161	3.42	No	Yes	0	7	8
45	R:R:D111	R:R:L49	56.6001	6.79	No	No	0	8	8
46	R:R:D111	R:R:Y52	45.0886	6.9	No	Yes	0	8	7
47	R:R:A131	R:R:Y52	15.4844	5.34	No	Yes	0	8	7
48	R:R:A131	R:R:I51	12.4161	4.87	No	No	0	8	7
49	R:R:C107	R:R:Y52	24.3649	9.41	No	Yes	0	7	7
50	R:R:N97	R:R:S59	21.7791	8.94	No	No	5	8	8
51	R:R:S100	R:R:S59	42.6913	3.26	No	No	0	7	8
52	R:R:S100	R:R:W139	18.9974	6.18	No	Yes	0	7	9
53	R:R:F104	R:R:W139	11.1798	7.02	No	Yes	0	7	9
54	R:R:C170	R:R:W70	14.4139	3.92	No	No	0	9	7
55	R:R:F167	R:R:T168	28.6694	2.59	Yes	No	0	3	5
56	R:R:T168	R:R:W80	14.6023	3.64	No	No	0	5	9
57	R:R:F82	R:R:W80	12.2051	14.03	No	No	0	8	9
58	R:R:C170	R:R:C87	12.2051	7.28	No	No	0	9	9
59	R:R:Y171	R:R:Y95	27.3426	15.89	Yes	Yes	1	3	5
60	R:R:M94	R:R:Y95	69.8153	9.58	No	Yes	0	7	5
61	R:R:E142	R:R:S100	21.6736	4.31	Yes	No	0	8	7
62	R:R:E142	R:R:N146	13.9389	9.2	Yes	No	0	8	7
63	R:R:F92	R:R:N146	11.1798	13.29	No	No	0	6	7
64	R:R:Y95	R:R:Y99	49.2348	8.94	Yes	Yes	1	5	7
65	R:R:R187	R:R:Y95	10.4485	22.64	Yes	Yes	1	5	5
66	R:R:F98	R:R:Y99	63.2341	9.28	Yes	Yes	1	8	7
67	R:R:F239	R:R:F98	90.1696	7.5	Yes	Yes	0	9	8
68	R:R:F242	R:R:F98	50.2827	7.5	Yes	Yes	1	7	8
69	R:R:F98	R:R:H243	12.6423	7.92	Yes	Yes	1	8	8
70	R:R:F239	R:R:T102	13.3811	3.89	Yes	No	0	9	8
71	R:R:P195	R:R:T102	11.1873	5.25	No	No	0	9	8
72	R:R:A109	R:R:I199	28.0211	3.25	No	No	0	9	8
73	R:R:F235	R:R:I199	49.9058	3.77	No	No	0	9	8
74	R:R:F235	R:R:F239	51.3607	7.5	No	Yes	0	9	9
75	R:R:A109	R:R:C202	25.9555	3.61	No	No	0	9	7
76	R:R:C202	R:R:Y113	21.7791	4.03	No	Yes	0	7	8
77	R:R:Y113	R:R:Y118	11.0366	6.95	Yes	Yes	2	8	6
78	R:R:C107	R:R:V134	21.3419	1.71	No	No	0	7	6
79	R:R:F130	R:R:V134	15.4844	6.55	Yes	No	0	3	6
80	R:R:G191	R:R:Y99	18.0249	2.9	No	Yes	0	5	7
81	R:R:G191	R:R:T190	15.8236	3.64	No	No	0	5	4
82	R:R:F186	R:R:T190	11.3758	10.38	No	No	0	3	4
83	R:R:E154	R:R:Y171	30.1696	10.1	No	Yes	1	4	3
84	R:R:E154	R:R:Q180	19.3366	10.19	No	Yes	1	4	3
85	R:R:T168	R:R:V157	12.2051	3.17	No	No	0	5	1
86	R:R:L176	R:R:Q180	17.2936	5.32	Yes	Yes	1	1	3
87	R:R:I181	R:R:L176	13.0192	4.28	Yes	Yes	0	3	1
88	R:R:F242	R:R:Y272	50.0565	9.28	Yes	Yes	1	7	4
89	R:R:R249	R:R:Y272	40.8368	14.4	Yes	Yes	1	4	4
90	R:R:L176	R:R:R249	15.1527	8.5	Yes	Yes	1	1	4
91	R:R:H243	R:R:Y192	10.8255	27.22	Yes	No	0	8	9
92	R:R:T240	R:R:Y192	10.3581	4.99	No	No	0	5	9
93	R:R:I199	R:R:N203	30.3129	1.42	No	Yes	0	8	9
94	R:R:N203	R:R:T232	12.0995	4.39	Yes	No	0	9	8
95	R:R:L228	R:R:N203	23.4225	2.75	Yes	Yes	0	8	9
96	R:R:L228	R:R:Y207	12.0769	1.17	Yes	Yes	0	8	5
97	R:R:I288	R:R:V284	10.4561	1.54	No	No	0	7	7
98	R:R:I231	R:R:Y290	33.7882	4.84	No	No	0	8	9
99	R:R:I231	R:R:L289	13.4414	4.28	No	No	0	8	8
100	R:R:I231	R:R:N203	29.7701	1.42	No	Yes	0	8	9
101	R:R:F239	R:R:N282	54.2179	10.87	Yes	No	0	9	9
102	R:R:M245	R:R:Y272	27.7799	4.79	Yes	Yes	0	5	4
103	R:R:I248	R:R:M245	10.8783	2.92	No	Yes	0	4	5
104	R:R:M245	R:R:M271	10.8783	2.89	Yes	No	0	5	6
105	R:R:L305	R:R:M301	20	4.24	No	Yes	0	6	5
106	R:R:I304	R:R:L305	17.5499	1.43	No	No	0	4	6
107	R:R:D300	R:R:I304	10.1244	5.6	No	No	0	4	4
108	R:R:M301	R:R:R298	10.1244	6.2	Yes	No	0	5	8
109	R:R:D286	R:R:N282	53.3434	14.81	No	No	0	9	9
110	R:R:R249	R:R:Y269	26.3325	4.12	Yes	No	0	4	4
111	R:R:E253	R:R:R249	14.444	16.28	Yes	Yes	1	4	4
112	R:R:S101	R:R:S59	23.4452	6.52	No	No	5	9	8
113	R:R:R187	R:R:Y99	12.2277	16.46	Yes	Yes	1	5	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9BHL_nogp

PDB Summary
PDB	9BHL_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.25
Number of Linked Nodes	285
Number of Links	308
Number of Hubs	33
Number of Links mediated by Hubs	120
Number of Communities	6
Number of Nodes involved in Communities	39
Number of Links involved in Communities	51

Path Summary
Number Of Nodes in MetaPath	114
Number Of Links MetaPath	113
Number of Shortest Paths	47470
Length Of Smallest Path	3
Average Path Length	13.3236
Length of Longest Path	28
Minimum Path Strength	1.27
Average Path Strength	6.56443
Maximum Path Strength	20.43
Minimum Path Correlation	0.7
Average Path Correlation	0.931228
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	54.0659
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	32.9805
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • apoptotic process • cell death • programmed cell death • response to pH • response to abiotic stimulus • response to acidic pH • immune response • immune system process • positive regulation of organelle organization • regulation of cytoskeleton organization • regulation of cellular component organization • regulation of actin filament-based process • positive regulation of cellular component organization • positive regulation of biological process • regulation of actin filament bundle assembly • cellular component biogenesis • cellular component organization • cellular component assembly • positive regulation of actin filament bundle assembly • actin filament bundle organization • positive regulation of stress fiber assembly • actin filament-based process • cellular component organization or biogenesis • stress fiber assembly • positive regulation of cellular process • regulation of actin filament organization • actin cytoskeleton organization • actomyosin structure organization • positive regulation of cellular component biogenesis • positive regulation of cytoskeleton organization • actin filament organization • regulation of cellular component biogenesis • positive regulation of supramolecular fiber organization • regulation of organelle organization • regulation of stress fiber assembly • organelle organization • contractile actin filament bundle assembly • regulation of actomyosin structure organization • regulation of actin cytoskeleton organization • actin filament bundle assembly • regulation of supramolecular fiber organization • supramolecular fiber organization • cytoskeleton organization
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8IYL9
Sequence	>9BHL_nogp_Chain_R C I E E Q H D L D H Y L F P I V Y I F V I I V S I P A N I G S L C V S F L Q A K K E S E L G I Y L F S L S L S D L L Y A L T L P L W I D Y T W N K D N W T F S P A L C K G S A F L M Y M N F Y S S T A F L T C I A V D R Y L A V V Y P L K F F F L R T R R F A L M V S L S I W I L E T I F N A V M L W E D E T V V E Y C D A E K S N F T L C Y D K Y P L E K W Q I N L N L F R T C T G Y A I P L V T I L I C N R K V Y Q A V R H N K A T E N K E K K R I I K L L V S I T V T F V L C F T P F H V M L L I R C I L E H A V N F E D H S N S G K R T Y T M Y R I T V A L T S L N C V A D P I L Y C F V T E T G R Y D M W N I L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9BHL	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHL (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9JFT	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1/γ2	3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w
	9JFT (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w

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