psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E8	R:R:H10	12.31	No	Yes	3	3	5
2	R:R:D172	R:R:E8	3.9	Yes	No	3	5	3
3	R:R:E8	R:R:R273	5.82	No	Yes	3	3	4
4	R:R:K266	R:R:Q9	6.78	No	No	0	3	3
5	R:R:D13	R:R:H10	6.3	Yes	Yes	3	4	5
6	R:R:H10	R:R:K77	5.24	Yes	No	0	5	4
7	R:R:D78	R:R:H10	7.56	Yes	Yes	3	5	5
8	R:R:D11	R:R:Y15	8.05	No	No	0	5	3
9	R:R:D13	R:R:L12	4.07	Yes	No	0	4	6
10	R:R:L12	R:R:L16	4.15	No	No	0	6	6
11	R:R:I274	R:R:L12	5.71	No	No	0	5	6
12	R:R:D13	R:R:F17	3.58	Yes	No	3	4	6
13	R:R:D13	R:R:D78	9.31	Yes	Yes	3	4	5
14	R:R:D13	R:R:R273	17.87	Yes	Yes	3	4	4
15	R:R:H14	R:R:Y15	18.51	No	No	0	6	3
16	R:R:H14	R:R:W75	16.93	No	Yes	0	6	4
17	R:R:F17	R:R:T74	10.38	No	No	0	6	5
18	R:R:F17	R:R:R273	3.21	No	Yes	3	6	4
19	R:R:V20	R:R:Y21	3.79	No	Yes	0	4	8
20	R:R:L67	R:R:Y21	4.69	Yes	Yes	1	8	8
21	R:R:I71	R:R:Y21	6.04	No	Yes	1	7	8
22	R:R:A277	R:R:Y21	4	No	Yes	0	6	8
23	R:R:S280	R:R:Y21	11.45	No	Yes	0	7	8
24	R:R:S280	R:R:V24	4.85	No	No	0	7	7
25	R:R:I25	R:R:I29	4.42	Yes	Yes	0	7	5
26	R:R:I25	R:R:L67	7.14	Yes	Yes	0	7	8
27	R:R:I25	R:R:P68	3.39	Yes	No	0	7	9
28	R:R:V27	R:R:V284	3.21	No	No	0	7	7
29	R:R:N32	R:R:S28	4.47	Yes	No	0	9	8
30	R:R:I29	R:R:P30	3.39	Yes	No	0	5	5
31	R:R:I29	R:R:L61	4.28	Yes	No	0	5	8
32	R:R:A64	R:R:I29	3.25	No	Yes	0	5	5
33	R:R:A31	R:R:P287	3.74	No	No	0	7	9
34	R:R:D60	R:R:N32	8.08	No	Yes	0	9	9
35	R:R:L61	R:R:N32	10.98	No	Yes	0	8	9
36	R:R:N32	R:R:P287	3.26	Yes	No	0	9	9
37	R:R:C37	R:R:G34	3.92	No	No	0	3	6
38	R:R:S35	R:R:S57	6.52	No	No	0	8	8
39	R:R:C291	R:R:S35	3.44	Yes	No	0	7	8
40	R:R:L36	R:R:S57	6.01	No	No	0	7	8
41	R:R:L36	R:R:L58	4.15	No	No	0	7	6
42	R:R:C291	R:R:V38	3.42	Yes	No	0	7	7
43	R:R:F54	R:R:S39	5.28	No	No	0	6	7
44	R:R:F40	R:R:K44	8.69	No	No	0	3	6
45	R:R:K44	R:R:L41	5.64	No	No	0	6	4
46	R:R:E46	R:R:R128	9.3	No	No	0	6	2
47	R:R:E48	R:R:R126	3.49	No	No	0	6	6
48	R:R:I108	R:R:L49	5.71	No	No	0	9	8
49	R:R:D111	R:R:L49	5.43	No	No	0	8	8
50	R:R:L49	R:R:R112	3.64	No	No	0	8	9
51	R:R:A131	R:R:I51	6.5	No	Yes	0	8	7
52	R:R:I51	R:R:L132	7.14	Yes	No	0	7	3
53	R:R:I51	R:R:S135	3.1	Yes	No	0	7	7
54	R:R:C107	R:R:Y52	5.38	No	Yes	0	7	7
55	R:R:D111	R:R:Y52	6.9	No	Yes	0	8	7
56	R:R:A131	R:R:Y52	4	No	Yes	0	8	7
57	R:R:V134	R:R:Y52	7.57	No	Yes	0	6	7
58	R:R:L53	R:R:Y290	3.52	No	Yes	0	8	9
59	R:R:C291	R:R:L53	3.17	Yes	No	0	7	8
60	R:R:F54	R:R:L58	7.31	No	No	0	6	6
61	R:R:F104	R:R:S55	17.18	Yes	No	0	7	9
62	R:R:S135	R:R:S55	4.89	No	No	0	7	9
63	R:R:D60	R:R:L56	8.14	No	No	4	9	9
64	R:R:F104	R:R:L56	4.87	Yes	No	4	7	9
65	R:R:D286	R:R:L56	10.86	Yes	No	4	9	9
66	R:R:S100	R:R:S59	6.52	No	No	4	7	8
67	R:R:F104	R:R:S59	3.96	Yes	No	4	7	8
68	R:R:S59	R:R:W139	7.41	No	Yes	4	8	9
69	R:R:D286	R:R:D60	11.98	Yes	No	4	9	9
70	R:R:L62	R:R:L93	5.54	No	No	0	7	5
71	R:R:L62	R:R:N97	4.12	No	Yes	0	7	8
72	R:R:L67	R:R:Y63	8.21	Yes	Yes	1	8	7
73	R:R:M94	R:R:Y63	8.38	No	Yes	0	7	7
74	R:R:N97	R:R:Y63	13.96	Yes	Yes	1	8	7
75	R:R:F98	R:R:Y63	9.28	Yes	Yes	1	8	7
76	R:R:S280	R:R:Y63	6.36	No	Yes	0	7	7
77	R:R:C283	R:R:Y63	6.72	No	Yes	1	8	7
78	R:R:L93	R:R:T66	10.32	No	No	0	5	7
79	R:R:I71	R:R:L67	7.14	No	Yes	1	7	8
80	R:R:L69	R:R:W80	6.83	No	Yes	2	7	9
81	R:R:L69	R:R:L86	4.15	No	Yes	2	7	6
82	R:R:L69	R:R:S90	6.01	No	No	2	7	5
83	R:R:W70	R:R:Y73	6.75	No	Yes	0	7	5
84	R:R:S90	R:R:W70	6.18	No	No	0	5	7
85	R:R:M94	R:R:W70	6.98	No	No	0	7	7
86	R:R:D72	R:R:W75	4.47	No	Yes	2	5	4
87	R:R:D72	R:R:N76	5.39	No	No	2	5	4
88	R:R:D78	R:R:Y73	6.9	Yes	Yes	0	5	5
89	R:R:W80	R:R:Y73	15.43	Yes	Yes	0	9	5
90	R:R:C170	R:R:Y73	4.03	No	Yes	0	9	5
91	R:R:N76	R:R:W75	9.04	No	Yes	2	4	4
92	R:R:D172	R:R:D78	3.99	Yes	Yes	3	5	5
93	R:R:F167	R:R:N79	25.37	No	No	0	3	4
94	R:R:F82	R:R:W80	9.02	Yes	Yes	2	8	9
95	R:R:L86	R:R:W80	9.11	Yes	Yes	2	6	9
96	R:R:C87	R:R:W80	13.06	No	Yes	2	9	9
97	R:R:S90	R:R:W80	3.71	No	Yes	2	5	9
98	R:R:T168	R:R:W80	3.64	No	Yes	0	5	9
99	R:R:F82	R:R:T81	5.19	Yes	No	0	8	3
100	R:R:F82	R:R:L86	3.65	Yes	Yes	2	8	6
101	R:R:L86	R:R:S83	4.5	Yes	No	0	6	8
102	R:R:P84	R:R:T155	8.74	No	Yes	0	2	5
103	R:R:C87	R:R:T155	5.07	No	Yes	2	9	5
104	R:R:C170	R:R:C87	7.28	No	No	2	9	9
105	R:R:D153	R:R:K88	8.3	No	No	0	5	7
106	R:R:K88	R:R:T155	4.5	No	Yes	0	7	5
107	R:R:A91	R:R:M149	3.22	No	No	0	5	4
108	R:R:Y95	R:R:Y99	5.96	No	Yes	6	5	7
109	R:R:Y171	R:R:Y95	11.91	No	No	0	3	5
110	R:R:R187	R:R:Y95	7.2	Yes	No	6	5	5
111	R:R:M96	R:R:W139	3.49	Yes	Yes	0	5	9
112	R:R:E142	R:R:M96	4.06	No	Yes	0	8	5
113	R:R:M96	R:R:N146	4.21	Yes	No	0	5	7
114	R:R:F98	R:R:N97	6.04	Yes	Yes	1	8	8
115	R:R:C283	R:R:N97	3.15	No	Yes	1	8	8
116	R:R:F242	R:R:F98	4.29	Yes	Yes	1	7	8
117	R:R:F98	R:R:T279	9.08	Yes	No	1	8	8
118	R:R:T102	R:R:Y99	3.75	No	Yes	0	8	7
119	R:R:E142	R:R:Y99	4.49	No	Yes	0	8	7
120	R:R:R187	R:R:Y99	12.35	Yes	Yes	6	5	7
121	R:R:H243	R:R:Y99	4.36	Yes	Yes	0	8	7
122	R:R:F104	R:R:S100	3.96	Yes	No	4	7	7
123	R:R:S100	R:R:W139	3.71	No	Yes	4	7	9
124	R:R:N282	R:R:S101	4.47	No	No	0	9	9
125	R:R:F239	R:R:T102	3.89	No	No	0	9	8
126	R:R:A103	R:R:I138	4.87	No	No	0	6	7
127	R:R:F104	R:R:I138	8.79	Yes	No	0	7	7
128	R:R:F104	R:R:W139	11.02	Yes	Yes	4	7	9
129	R:R:L105	R:R:Y290	7.03	No	Yes	0	9	9
130	R:R:P195	R:R:T106	5.25	No	No	0	9	8
131	R:R:T106	R:R:T198	6.28	No	No	0	8	6
132	R:R:I108	R:R:Y290	7.25	No	Yes	0	9	9
133	R:R:R112	R:R:Y290	4.12	No	Yes	0	9	9
134	R:R:L114	R:R:Y113	3.52	No	Yes	5	6	8
135	R:R:V117	R:R:Y113	7.57	No	Yes	5	7	8
136	R:R:Y113	R:R:Y118	9.93	Yes	Yes	5	8	6
137	R:R:C202	R:R:Y113	6.72	Yes	Yes	0	7	8
138	R:R:K205	R:R:Y113	5.97	No	Yes	0	4	8
139	R:R:F122	R:R:L114	7.31	Yes	No	5	5	6
140	R:R:L114	R:R:L125	5.54	No	No	5	6	3
141	R:R:V117	R:R:Y118	12.62	No	Yes	5	7	6
142	R:R:F122	R:R:Y118	5.16	Yes	Yes	5	5	6
143	R:R:F122	R:R:K121	3.72	Yes	No	0	5	5
144	R:R:F122	R:R:L125	3.65	Yes	No	5	5	3
145	R:R:F123	R:R:R126	3.21	No	No	0	5	6
146	R:R:F124	R:R:L125	7.31	No	No	0	5	3
147	R:R:F130	R:R:V134	3.93	No	No	0	3	6
148	R:R:F145	R:R:L141	6.09	No	No	0	5	5
149	R:R:F145	R:R:I144	3.77	No	No	0	5	4
150	R:R:F145	R:R:F186	4.29	No	No	0	5	3
151	R:R:E154	R:R:M149	6.77	Yes	No	0	4	4
152	R:R:E152	R:R:W151	4.36	No	No	0	5	4
153	R:R:E152	R:R:E177	10.15	No	No	0	5	2
154	R:R:E154	R:R:Y171	8.98	Yes	No	0	4	3
155	R:R:E154	R:R:E177	5.07	Yes	No	7	4	2
156	R:R:E154	R:R:Q180	7.65	Yes	Yes	7	4	3
157	R:R:T155	R:R:T168	3.14	Yes	No	0	5	5
158	R:R:C170	R:R:T155	5.07	No	Yes	2	9	5
159	R:R:E158	R:R:V156	5.7	No	No	0	2	2
160	R:R:E158	R:R:L169	9.28	No	No	0	2	3
161	R:R:E158	R:R:K173	6.75	No	No	0	2	4
162	R:R:N166	R:R:Y159	4.65	No	No	0	4	1
163	R:R:F167	R:R:L169	4.87	No	No	0	3	3
164	R:R:Y171	R:R:Y272	4.96	No	Yes	0	3	4
165	R:R:D172	R:R:Y269	11.49	Yes	No	0	5	4
166	R:R:D172	R:R:R273	7.15	Yes	Yes	3	5	4
167	R:R:P175	R:R:Y174	8.34	No	No	8	3	5
168	R:R:E253	R:R:Y174	5.61	No	No	8	4	5
169	R:R:E253	R:R:P175	9.43	No	No	8	4	3
170	R:R:L176	R:R:Q180	5.32	No	Yes	0	1	3
171	R:R:L176	R:R:R249	9.72	No	No	0	1	4
172	R:R:E177	R:R:Q180	16.57	No	Yes	7	2	3
173	R:R:N182	R:R:W179	6.78	No	No	0	4	3
174	R:R:L183	R:R:Q180	5.32	No	Yes	0	5	3
175	R:R:L183	R:R:R187	17.01	No	Yes	0	5	5
176	R:R:N184	R:R:R187	6.03	No	Yes	0	5	5
177	R:R:L246	R:R:N184	16.48	No	No	0	6	5
178	R:R:C250	R:R:N184	3.15	Yes	No	0	5	5
179	R:R:C250	R:R:L185	3.17	Yes	No	0	5	4
180	R:R:F186	R:R:T190	15.56	No	No	0	3	4
181	R:R:H243	R:R:T188	8.21	Yes	No	0	8	6
182	R:R:C189	R:R:T190	3.38	No	No	0	4	4
183	R:R:G191	R:R:P195	4.06	No	No	0	5	9
184	R:R:L196	R:R:Y192	5.86	No	Yes	0	7	9
185	R:R:T240	R:R:Y192	7.49	Yes	Yes	0	5	9
186	R:R:H243	R:R:Y192	16.33	Yes	Yes	0	8	9
187	R:R:I194	R:R:P195	3.39	No	No	0	6	9
188	R:R:L196	R:R:L200	4.15	No	No	0	7	5
189	R:R:F235	R:R:L196	6.09	No	No	0	9	7
190	R:R:F235	R:R:I199	5.02	No	No	0	9	8
191	R:R:L200	R:R:T232	4.42	No	No	0	5	8
192	R:R:L228	R:R:N203	6.87	Yes	No	0	8	9
193	R:R:N203	R:R:T232	4.39	No	No	0	9	8
194	R:R:Q208	R:R:R204	4.67	No	No	0	4	3
195	R:R:L228	R:R:V206	4.47	Yes	No	0	8	8
196	R:R:R211	R:R:Y207	9.26	No	Yes	9	4	5
197	R:R:I225	R:R:Y207	6.04	No	Yes	9	6	5
198	R:R:I224	R:R:V210	7.68	No	No	0	7	8
199	R:R:I225	R:R:R211	6.26	No	No	9	6	4
200	R:R:N213	R:R:T216	8.77	No	No	0	5	2
201	R:R:K221	R:R:T216	6.01	No	No	0	6	2
202	R:R:E217	R:R:K219	6.75	No	No	0	3	4
203	R:R:K222	R:R:N218	8.39	No	No	0	5	3
204	R:R:R223	R:R:V293	3.92	No	No	0	7	7
205	R:R:L227	R:R:V293	7.45	No	No	0	8	7
206	R:R:L289	R:R:S230	6.01	Yes	No	0	8	5
207	R:R:I231	R:R:L289	4.28	No	Yes	0	8	8
208	R:R:I231	R:R:Y290	9.67	No	Yes	0	8	9
209	R:R:T240	R:R:V236	6.35	Yes	No	0	5	5
210	R:R:F239	R:R:N282	12.08	No	No	0	9	9
211	R:R:P241	R:R:T240	3.5	No	Yes	0	9	5
212	R:R:T240	R:R:V244	3.17	Yes	No	0	5	6
213	R:R:P241	R:R:T275	3.5	No	No	0	9	7
214	R:R:F242	R:R:H243	9.05	Yes	Yes	0	7	8
215	R:R:F242	R:R:L246	6.09	Yes	No	1	7	6
216	R:R:F242	R:R:Y272	8.25	Yes	Yes	1	7	4
217	R:R:F242	R:R:T279	9.08	Yes	No	1	7	8
218	R:R:I248	R:R:M245	7.29	No	No	0	4	5
219	R:R:M245	R:R:M271	10.11	No	No	0	5	6
220	R:R:L246	R:R:Y272	5.86	No	Yes	1	6	4
221	R:R:C250	R:R:L247	3.17	Yes	No	0	5	6
222	R:R:R249	R:R:Y269	8.23	No	No	0	4	4
223	R:R:G265	R:R:T268	3.64	No	No	0	1	4
224	R:R:M271	R:R:T268	4.52	No	No	0	6	4
225	R:R:Y269	R:R:Y272	11.91	No	Yes	0	4	4
226	R:R:R273	R:R:T270	6.47	Yes	No	0	4	2
227	R:R:T275	R:R:Y272	3.75	No	Yes	0	7	4
228	R:R:V276	R:R:Y272	3.79	No	Yes	0	6	4
229	R:R:D286	R:R:N282	8.08	Yes	No	0	9	9
230	R:R:D286	R:R:P287	8.05	Yes	No	0	9	9
231	R:R:F292	R:R:I288	5.02	No	No	0	7	7
232	R:R:T294	R:R:T296	3.14	No	No	0	8	7
233	R:R:G297	R:R:T296	3.64	No	No	0	8	7
234	R:R:I248	R:R:V244	3.07	No	No	0	4	6
235	R:R:M96	R:R:T143	3.01	Yes	No	0	5	4
236	R:R:K266	R:R:T270	3	No	No	0	3	2
237	R:R:L281	R:R:V24	2.98	No	No	0	5	7
238	R:R:L252	R:R:T268	2.95	No	No	0	3	4
239	R:R:I22	R:R:I71	2.94	No	No	0	5	7
240	R:R:I25	R:R:I26	2.94	Yes	No	0	7	6
241	R:R:N79	R:R:T81	2.92	No	No	0	4	3
242	R:R:G265	R:R:Y174	2.9	No	No	0	1	5
243	R:R:Q42	R:R:S47	2.89	No	No	0	5	8
244	R:R:I224	R:R:L228	2.85	No	Yes	0	7	8
245	R:R:I234	R:R:L289	2.85	No	Yes	0	6	8
246	R:R:I251	R:R:L247	2.85	No	No	0	5	6
247	R:R:Q42	R:R:T296	2.83	No	No	0	5	7
248	R:R:E220	R:R:T216	2.82	No	No	0	5	2
249	R:R:C160	R:R:F167	2.79	No	No	0	1	3
250	R:R:C238	R:R:F239	2.79	No	No	0	8	9
251	R:R:C291	R:R:F292	2.79	Yes	No	0	7	7
252	R:R:A115	R:R:R126	2.77	No	No	0	8	6
253	R:R:P18	R:R:W75	2.7	No	Yes	0	5	4
254	R:R:H254	R:R:I181	2.65	No	No	0	1	3
255	R:R:F23	R:R:V27	2.62	No	No	0	5	7
256	R:R:D111	R:R:E48	2.6	No	No	0	8	6
257	R:R:R129	R:R:T127	2.59	No	No	0	4	6
258	R:R:F23	R:R:I26	2.51	No	No	0	5	6
259	R:R:F92	R:R:M149	2.49	No	No	0	6	4
260	R:R:D72	R:R:F82	2.39	No	Yes	2	5	8
261	R:R:E295	R:R:R298	2.33	No	No	0	5	8
262	R:R:R204	R:R:Y207	2.06	No	Yes	0	3	5
263	R:R:G50	R:R:S47	1.86	No	No	0	7	8
264	R:R:G297	R:R:V38	1.84	No	No	0	8	7
265	R:R:G191	R:R:T102	1.82	No	No	0	5	8
266	R:R:G191	R:R:T190	1.82	No	No	0	5	4
267	R:R:A109	R:R:C202	1.81	No	Yes	0	9	7
268	R:R:A285	R:R:C238	1.81	No	No	0	7	8
269	R:R:G34	R:R:I33	1.76	No	No	0	6	4
270	R:R:G89	R:R:K88	1.74	No	No	0	5	7
271	R:R:A85	R:R:S83	1.71	No	No	0	2	8
272	R:R:C202	R:R:V110	1.71	Yes	No	0	7	6
273	R:R:A209	R:R:V116	1.7	No	No	0	5	8
274	R:R:A209	R:R:V117	1.7	No	No	0	5	7
275	R:R:C202	R:R:T198	1.69	Yes	No	0	7	6
276	R:R:L120	R:R:P119	1.64	No	No	0	6	9
277	R:R:C250	R:R:I181	1.64	Yes	No	0	5	3
278	R:R:L278	R:R:P241	1.64	No	No	0	8	9
279	R:R:A43	R:R:I51	1.62	No	Yes	0	6	7
280	R:R:V229	R:R:V233	1.6	No	No	0	4	5
281	R:R:T168	R:R:V157	1.59	No	No	0	5	1
282	R:R:A215	R:R:N213	1.56	No	No	0	1	5
283	R:R:M133	R:R:S137	1.53	No	No	0	3	4
284	R:R:K221	R:R:V210	1.52	No	No	0	6	8
285	R:R:L183	R:R:V148	1.49	No	No	0	5	7
286	R:R:I29	R:R:I33	1.47	Yes	No	0	5	4
287	R:R:I201	R:R:K205	1.45	No	No	0	5	4
288	R:R:K221	R:R:N218	1.4	No	No	0	6	3
289	R:R:A43	R:R:F40	1.39	No	No	0	6	3
290	R:R:P119	R:R:Y118	1.39	No	Yes	0	9	6
291	R:R:L227	R:R:L289	1.38	No	Yes	0	8	8
292	R:R:E220	R:R:K219	1.35	No	No	0	5	4
293	R:R:A193	R:R:Y192	1.33	No	Yes	0	5	9
294	R:R:F130	R:R:T127	1.3	No	No	0	3	6
295	R:R:R128	R:R:T127	1.29	No	No	0	2	6
296	R:R:H254	R:R:N257	1.28	No	No	0	1	2
297	R:R:M271	R:R:R267	1.24	No	No	0	6	4
298	R:R:L228	R:R:Y207	1.17	Yes	Yes	0	8	5
299	R:R:E295	R:R:Y299	1.12	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:H10	7.8525	4	3	5
2	R:R:D13	8.226	5	3	4
3	R:R:Y21	5.994	5	1	8
4	R:R:I25	4.4725	4	0	7
5	R:R:I29	3.362	5	0	5
6	R:R:N32	6.6975	4	0	9
7	R:R:I51	4.59	4	0	7
8	R:R:Y52	5.9625	4	0	7
9	R:R:Y63	8.81833	6	1	7
10	R:R:L67	6.795	4	1	8
11	R:R:Y73	8.2775	4	0	5
12	R:R:W75	8.285	4	2	4
13	R:R:D78	6.94	4	3	5
14	R:R:W80	8.68571	7	2	9
15	R:R:F82	5.0625	4	2	8
16	R:R:L86	5.3525	4	2	6
17	R:R:M96	3.6925	4	0	5
18	R:R:N97	6.8175	4	1	8
19	R:R:F98	7.1725	4	1	8
20	R:R:Y99	6.182	5	6	7
21	R:R:F104	8.29667	6	4	7
22	R:R:Y113	6.742	5	5	8
23	R:R:Y118	7.275	4	5	6
24	R:R:F122	4.96	4	5	5
25	R:R:W139	6.4075	4	4	9
26	R:R:E154	7.1175	4	7	4
27	R:R:T155	5.304	5	2	5
28	R:R:D172	6.6325	4	3	5
29	R:R:Q180	8.715	4	7	3
30	R:R:R187	10.6475	4	6	5
31	R:R:Y192	7.7525	4	0	9
32	R:R:C202	2.9825	4	0	7
33	R:R:Y207	4.6325	4	9	5
34	R:R:L228	3.84	4	0	8
35	R:R:T240	5.1275	4	0	5
36	R:R:F242	7.352	5	1	7
37	R:R:H243	9.4875	4	0	8
38	R:R:C250	2.7825	4	0	5
39	R:R:Y272	6.42	6	1	4
40	R:R:R273	8.104	5	3	4
41	R:R:D286	9.7425	4	4	9
42	R:R:L289	3.63	4	0	8
43	R:R:Y290	6.318	5	0	9
44	R:R:C291	3.205	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D72	R:R:W75	14.0366	4.47	No	Yes	2	5	4
2	R:R:D72	R:R:F82	19.6313	2.39	No	Yes	2	5	8
3	R:R:F82	R:R:W80	44.159	9.02	Yes	Yes	2	8	9
4	R:R:W80	R:R:Y73	43.4819	15.43	Yes	Yes	0	9	5
5	R:R:D78	R:R:Y73	34.8013	6.9	Yes	Yes	0	5	5
6	R:R:D172	R:R:D78	38.7819	3.99	Yes	Yes	3	5	5
7	R:R:W70	R:R:Y73	28.1185	6.75	No	Yes	0	7	5
8	R:R:M94	R:R:W70	52.081	6.98	No	No	0	7	7
9	R:R:M94	R:R:Y63	52.8306	8.38	No	Yes	0	7	7
10	R:R:L67	R:R:Y63	29.2791	8.21	Yes	Yes	1	8	7
11	R:R:D172	R:R:Y269	52.1112	11.49	Yes	No	0	5	4
12	R:R:Y269	R:R:Y272	53.0724	11.91	No	Yes	0	4	4
13	R:R:F242	R:R:Y272	29.9199	8.25	Yes	Yes	1	7	4
14	R:R:F242	R:R:F98	42.8261	4.29	Yes	Yes	1	7	8
15	R:R:F98	R:R:Y63	39.5859	9.28	Yes	Yes	1	8	7
16	R:R:I25	R:R:L67	28.318	7.14	Yes	Yes	0	7	8
17	R:R:I25	R:R:I29	26.3412	4.42	Yes	Yes	0	7	5
18	R:R:I29	R:R:L61	25.9241	4.28	Yes	No	0	5	8
19	R:R:L61	R:R:N32	25.9	10.98	No	Yes	0	8	9
20	R:R:D286	R:R:N282	14.0577	8.08	Yes	No	0	9	9
21	R:R:F239	R:R:N282	15.0552	12.08	No	No	0	9	9
22	R:R:F239	R:R:T102	16.7327	3.89	No	No	0	9	8
23	R:R:T102	R:R:Y99	40.3355	3.75	No	Yes	0	8	7
24	R:R:Y95	R:R:Y99	26.0148	5.96	No	Yes	6	5	7
25	R:R:Y171	R:R:Y95	25.9816	11.91	No	No	0	3	5
26	R:R:Y171	R:R:Y272	25.643	4.96	No	Yes	0	3	4
27	R:R:H243	R:R:Y99	71.8573	4.36	Yes	Yes	0	8	7
28	R:R:F242	R:R:H243	68.0762	9.05	Yes	Yes	0	7	8
29	R:R:E142	R:R:Y99	76.7719	4.49	No	Yes	0	8	7
30	R:R:E142	R:R:M96	76.107	4.06	No	Yes	0	8	5
31	R:R:M96	R:R:W139	74.23	3.49	Yes	Yes	0	5	9
32	R:R:F104	R:R:W139	71.8543	11.02	Yes	Yes	4	7	9
33	R:R:F104	R:R:S55	100	17.18	Yes	No	0	7	9
34	R:R:S135	R:R:S55	98.924	4.89	No	No	0	7	9
35	R:R:I51	R:R:S135	97.8419	3.1	Yes	No	0	7	7
36	R:R:A131	R:R:I51	91.2226	6.5	No	Yes	0	8	7
37	R:R:A131	R:R:Y52	90.0982	4	No	Yes	0	8	7
38	R:R:D111	R:R:Y52	80.8433	6.9	No	Yes	0	8	7
39	R:R:D111	R:R:L49	75.0582	5.43	No	No	0	8	8
40	R:R:I108	R:R:L49	36.9201	5.71	No	No	0	9	8
41	R:R:I108	R:R:Y290	35.6173	7.25	No	Yes	0	9	9
42	R:R:L53	R:R:Y290	47.3024	3.52	No	Yes	0	8	9
43	R:R:C291	R:R:L53	44.5852	3.17	Yes	No	0	7	8
44	R:R:C291	R:R:S35	16.8989	3.44	Yes	No	0	7	8
45	R:R:L49	R:R:R112	36.911	3.64	No	No	0	8	9
46	R:R:R112	R:R:Y290	35.6083	4.12	No	Yes	0	9	9
47	R:R:S35	R:R:S57	14.097	6.52	No	No	0	8	8
48	R:R:L36	R:R:S57	11.2891	6.01	No	No	0	7	8
49	R:R:C291	R:R:V38	19.6947	3.42	Yes	No	0	7	7
50	R:R:D286	R:R:L56	10.0257	10.86	Yes	No	4	9	9
51	R:R:F104	R:R:L56	32.477	4.87	Yes	No	4	7	9
52	R:R:S90	R:R:W70	23.6331	6.18	No	No	0	5	7
53	R:R:S90	R:R:W80	19.3139	3.71	No	Yes	2	5	9
54	R:R:C170	R:R:Y73	13.1903	4.03	No	Yes	0	9	5
55	R:R:F82	R:R:T81	22.3243	5.19	Yes	No	0	8	3
56	R:R:N79	R:R:T81	19.5436	2.92	No	No	0	4	3
57	R:R:F167	R:R:N79	16.7568	25.37	No	No	0	3	4
58	R:R:G191	R:R:T102	42.4482	1.82	No	No	0	5	8
59	R:R:G191	R:R:P195	32.9726	4.06	No	No	0	5	9
60	R:R:P195	R:R:T106	30.2101	5.25	No	No	0	9	8
61	R:R:T106	R:R:T198	28.8197	6.28	No	No	0	8	6
62	R:R:C202	R:R:T198	27.4233	1.69	Yes	No	0	7	6
63	R:R:C202	R:R:Y113	23.1978	6.72	Yes	Yes	0	7	8
64	R:R:F167	R:R:L169	11.1652	4.87	No	No	0	3	3
65	R:R:T240	R:R:V244	10.1043	3.17	Yes	No	0	5	6
66	R:R:H243	R:R:Y192	34.3539	16.33	Yes	Yes	0	8	9
67	R:R:L196	R:R:Y192	25.0778	5.86	No	Yes	0	7	9
68	R:R:L196	R:R:L200	22.1037	4.15	No	No	0	7	5
69	R:R:L200	R:R:T232	21.1002	4.42	No	No	0	5	8
70	R:R:N203	R:R:T232	20.0816	4.39	No	No	0	9	8
71	R:R:L228	R:R:N203	19.054	6.87	Yes	No	0	8	9
72	R:R:I224	R:R:L228	11.8483	2.85	No	Yes	0	7	8
73	R:R:I224	R:R:V210	10.872	7.68	No	No	0	7	8
74	R:R:I231	R:R:Y290	19.4741	9.67	No	Yes	0	8	9
75	R:R:I231	R:R:L289	16.8868	4.28	No	Yes	0	8	8
76	R:R:G297	R:R:V38	16.8989	1.84	No	No	0	8	7
77	R:R:G297	R:R:T296	14.097	3.64	No	No	0	8	7
78	R:R:D60	R:R:N32	24.4975	8.08	No	Yes	0	9	9
79	R:R:D60	R:R:L56	22.6145	8.14	No	No	4	9	9
80	R:R:D172	R:R:R273	11.1924	7.15	Yes	Yes	3	5	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9JFT_nogp

PDB Summary
PDB	9JFT_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.1
Number of Linked Nodes	265
Number of Links	299
Number of Hubs	44
Number of Links mediated by Hubs	162
Number of Communities	9
Number of Nodes involved in Communities	54
Number of Links involved in Communities	71

Path Summary
Number Of Nodes in MetaPath	81
Number Of Links MetaPath	80
Number of Shortest Paths	68452
Length Of Smallest Path	3
Average Path Length	17.913
Length of Longest Path	37
Minimum Path Strength	1.295
Average Path Strength	6.5303
Maximum Path Strength	17.72
Minimum Path Correlation	0.7
Average Path Correlation	0.924493
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.125
Average % Of Corr. Nodes	41.3228
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.2559
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein-containing complex binding • binding • G-protein beta/gamma-subunit complex binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell communication • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Biological Process
Gene Ontology	Cellular Component	• protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cellular anatomical structure • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • apoptotic process • cell death • programmed cell death • response to pH • response to abiotic stimulus • response to acidic pH • immune response • immune system process • positive regulation of organelle organization • regulation of cytoskeleton organization • regulation of cellular component organization • regulation of actin filament-based process • positive regulation of cellular component organization • positive regulation of biological process • regulation of actin filament bundle assembly • cellular component biogenesis • cellular component organization • cellular component assembly • positive regulation of actin filament bundle assembly • actin filament bundle organization • positive regulation of stress fiber assembly • actin filament-based process • cellular component organization or biogenesis • stress fiber assembly • positive regulation of cellular process • regulation of actin filament organization • actin cytoskeleton organization • actomyosin structure organization • positive regulation of cellular component biogenesis • positive regulation of cytoskeleton organization • actin filament organization • regulation of cellular component biogenesis • positive regulation of supramolecular fiber organization • regulation of organelle organization • regulation of stress fiber assembly • organelle organization • contractile actin filament bundle assembly • regulation of actomyosin structure organization • regulation of actin cytoskeleton organization • actin filament bundle assembly • regulation of supramolecular fiber organization • supramolecular fiber organization • cytoskeleton organization • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8IYL9
Sequence	>9JFT_nogp_Chain_R E Q H D L D H Y L F P I V Y I F V I I V S I P A N I G S L C V S F L Q A K K E S E L G I Y L F S L S L S D L L Y A L T L P L W I D Y T W N K D N W T F S P A L C K G S A F L M Y M N F Y S S T A F L T C I A V D R Y L A V V Y P L K F F F L R T R R F A L M V S L S I W I L E T I F N A V M L W E D E T V V E Y C N F T L C Y D K Y P L E K W Q I N L N L F R T C T G Y A I P L V T I L I C N R K V Y Q A V R H N K A T E N K E K K R I I K L L V S I T V F V L C F T P F H V M L L I R C I L E H A V N N S G K R T Y T M Y R I T V A L T S L N C V A D P I L Y C F V T E T G R Y I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9BHL	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHL (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9JFT	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1/γ2	3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w
	9JFT (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9JFT_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.