Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1A:A:L30 3.795445
2A:A:K34 4.5625404
3A:A:H41 6.142526
4A:A:L43 4.2675427
5A:A:L45 5.9525428
6A:A:L46 3.5325418
7A:A:S51 4.278529
8A:A:K53 7.845429
9A:A:I56 4.93427
10A:A:Q59 4.4125429
11A:A:M60 3.69833629
12A:A:I207 4.0875419
13A:A:F212 5.802529
14A:A:V217 3.4025425
15A:A:F219 7.818528
16A:A:H220 9.5775417
17A:A:M221 4.156528
18A:A:F222 9.294517
19A:A:V224 7.225419
20A:A:Q227 5.938519
21A:A:R232 8.1754178
22A:A:K233 5.768336179
23A:A:W234 8.046519
24A:A:C237 3.7775418
25A:A:F238 7.14167619
26A:A:I245 3.686527
27A:A:Y253 8.58538
28A:A:L270 5.64506
29A:A:F273 5.64839
30A:A:W277 10.48736
31A:A:W281 10.565615
32A:A:I288 4.526529
33A:A:L289 4.015439
34A:A:F290 5.31167629
35A:A:N292 3.9625409
36A:A:Q294 8.235436
37A:A:L297 4.08438
38A:A:V301 2.345437
39A:A:I308 8.0475437
40A:A:Y311 5.5475436
41A:A:F312 4.522538
42A:A:F315 13.5925436
43A:A:Y318 5.418536
44A:A:E330 9.14433
45A:A:V334 4.562534
46A:A:T335 4.4875404
47A:A:K338 8.6275435
48A:A:Y339 5.275633
49A:A:F340 7.78833637
50A:A:F345 6.47167638
51A:A:C359 4.18435
52A:A:Y360 10.272528
53A:A:F363 8.5175435
54A:A:T364 6.115429
55A:A:D368 8.87429
56A:A:N371 9.415629
57A:A:R373 6.27425
58A:A:I375 3.6625429
59A:A:F376 5.24833628
60A:A:I383 4.01667628
61A:A:Q384 4.38406
62A:A:R385 7.6225125
63A:A:H387 5.244528
64A:A:L388 3.644128
65A:A:Y391 8.28571724
66A:A:E392 8.654126
67A:A:L394 5.851676128
68B:B:L7 3.17408
69B:B:I18 3.8325457
70B:B:L30 4.546515
71B:B:Q32 5.7575411
72B:B:T34 3.365415
73B:B:I37 4.2225402
74B:B:V40 4.3954133
75B:B:L51 5.715449
76B:B:H54 8.756549
77B:B:K57 11.57419
78B:B:Y59 5.78418
79B:B:M61 4.296546
80B:B:W63 6.84714747
81B:B:L70 8.085445
82B:B:V71 4.8125108
83B:B:Q75 8.05419
84B:B:D76 7.432509
85B:B:K78 4.9125408
86B:B:L79 3.7654107
87B:B:I80 5.506548
88B:B:I81 4.294107
89B:B:W82 7.24143749
90B:B:D83 8.356548
91B:B:Y85 7.47544
92B:B:T86 7.5575446
93B:B:N88 11.1125447
94B:B:K89 4.39749
95B:B:I93 4.8275407
96B:B:L95 4.234108
97B:B:W99 8.09143719
98B:B:M101 5.38419
99B:B:Y105 3.91667606
100B:B:N110 5.0825464
101B:B:Y111 4.714564
102B:B:V112 4.75754108
103B:B:C114 4.3025108
104B:B:L117 4.84419
105B:B:C121 3.34468
106B:B:I123 3.8025466
107B:B:Y124 6.248336106
108B:B:T128 3.6625403
109B:B:L139 5.76569
110B:B:H142 6.30375869
111B:B:Y145 5.062508
112B:B:L146 3.765467
113B:B:R150 7.7925456
114B:B:F151 3.838509
115B:B:L152 4.874553
116B:B:D154 5.1466
117B:B:I157 3.612567
118B:B:V158 3.766555
119B:B:T159 6.048569
120B:B:D163 7.864569
121B:B:L168 3.3325406
122B:B:W169 9.36167668
123B:B:Q176 6.6125464
124B:B:F180 8.49557
125B:B:H183 6.09857759
126B:B:V187 5.1275459
127B:B:L190 3.77833655
128B:B:L192 3.716555
129B:B:F199 6.065659
130B:B:V200 8.5525476
131B:B:C204 6.1885177
132B:B:D205 6.7775459
133B:B:K209 7.38556
134B:B:W211 8.585658
135B:B:D212 5.8475409
136B:B:Q220 5.3575477
137B:B:F222 7.80667678
138B:B:H225 7.4675879
139B:B:I229 5.9375477
140B:B:F234 5.384505
141B:B:F235 7.90714716
142B:B:P236 6.365417
143B:B:N237 8.705415
144B:B:F241 8.05857776
145B:B:T243 5.89578
146B:B:S245 7.07479
147B:B:D247 8.056579
148B:B:T249 6.924576
149B:B:R251 11.24478
150B:B:F253 6.85167676
151B:B:L255 3.17476
152B:B:D258 11.0125477
153B:B:Q259 4.068506
154B:B:M262 4.945414
155B:B:T263 6.915471
156B:B:Y264 4.66333615
157B:B:C271 5.1415
158B:B:F278 7.88517
159B:B:R283 6.1345139
160B:B:L285 6.27516
161B:B:Y289 8.52333617
162B:B:D290 5.63516
163B:B:C294 4.32405
164B:B:N295 6.868516
165B:B:V296 4.5575405
166B:B:W297 5.534518
167B:B:L300 3.275416
168B:B:K301 6.005405
169B:B:L308 7.025407
170B:B:H311 8.3525159
171B:B:R314 10.6483618
172B:B:T329 6.18408
173B:B:W332 11.3257719
174B:B:D333 7.6885159
175B:B:L336 4.124547
176B:B:K337 5.4925156
177B:B:I338 4.1275445
178G:G:Q18 6.39459
179G:G:L19 5.755459
180G:G:E22 9.9275459
181G:G:Y40 7.5125416
182G:G:D48 7.35254139
183G:G:L51 3.0745136
184G:G:F61 5.14748
185R:R:E8 6.174143
186R:R:H10 7.85254145
187R:R:D13 8.2265144
188R:R:F17 4.9854146
189R:R:Y21 5.06714798
190R:R:I25 4.4725407
191R:R:I29 3.362505
192R:R:N32 5.954509
193R:R:L36 3.84254197
194R:R:L49 4.575428
195R:R:I51 4.59407
196R:R:Y52 5.278507
197R:R:L56 6.7175489
198R:R:Y63 7.98429797
199R:R:L67 6.795498
200R:R:W70 5.625407
201R:R:Y73 8.2775405
202R:R:W75 8.2854114
203R:R:D78 6.135145
204R:R:W80 8.685717119
205R:R:F82 5.06254118
206R:R:L86 5.35254116
207R:R:M96 3.52585
208R:R:N97 6.8175498
209R:R:F98 7.1725498
210R:R:Y99 6.182587
211R:R:F104 7.48857787
212R:R:D111 5.745428
213R:R:Y113 6.7425168
214R:R:L120 4.182526
215R:R:F122 4.964165
216R:R:R126 4.63526
217R:R:S135 3.2925487
218R:R:W139 6.4075489
219R:R:E154 7.11754204
220R:R:T155 5.3045115
221R:R:D172 6.63254145
222R:R:Q180 8.7154203
223R:R:N184 7.145405
224R:R:R187 10.6475485
225R:R:Y192 7.7525409
226R:R:Y207 4.63254235
227R:R:T216 6.6654122
228R:R:E220 7.01254125
229R:R:I224 4.05754127
230R:R:L228 3.626508
231R:R:T240 5.1275405
232R:R:F242 5.99571797
233R:R:H243 9.4875408
234R:R:C250 2.7825405
235R:R:Y272 6.42694
236R:R:R273 8.1045144
237R:R:T275 3.2125497
238R:R:D286 9.7425489
239R:R:L289 3.63408
240R:R:Y290 6.318529
241R:R:C291 3.205407
242R:R:T296 5.2254127
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1B:B:A56 B:B:D76 15.31563.09NoYes079
2A:A:Y37 B:B:A56 15.37672.67NoNo047
3A:A:R42 A:A:Y37 17.94218.52NoNo094
4A:A:H387 A:A:I383 74.8376.63YesYes288
5A:A:H41 A:A:I383 75.34645.3YesYes268
6A:A:F219 A:A:H41 79.67687.92YesYes286
7A:A:F219 A:A:L43 56.78266.09YesYes287
8A:A:L43 A:A:M221 28.44142.83YesYes278
9A:A:L45 A:A:M221 57.20987.07YesYes288
10A:A:K53 A:A:L45 94.02228.46YesYes298
11A:A:K53 A:A:S51 94.127.65YesYes299
12A:A:A48 A:A:S51 95.89881.71NoYes089
13A:A:A48 A:A:R265 95.94742.77NoNo089
14A:A:D252 A:A:R265 95.99617.15NoNo089
15A:A:D252 A:A:N254 96.14185.39NoNo089
16A:A:N254 A:A:Y311 96.19046.98NoYes096
17A:A:Y253 A:A:Y311 96.31317.94YesYes386
18A:A:I308 A:A:Y253 97.235712.09YesYes378
19A:A:F312 A:A:I308 97.20663.77YesYes387
20A:A:F312 A:A:L266 39.63388.53YesNo388
21A:A:F345 A:A:L266 39.62192.44YesNo388
22A:A:F345 A:A:V248 39.91849.18YesNo087
23A:A:F246 A:A:V248 39.8945.24NoNo097
24A:A:F246 A:A:L272 1004.87NoNo098
25A:A:L272 A:A:R231 99.95154.86NoNo089
26A:A:R231 A:A:W234 99.90326NoYes099
27A:A:F238 A:A:W234 37.20476.01YesYes199
28A:A:F238 A:A:V241 17.70823.93YesNo099
29A:A:R42 A:A:V241 17.63222.62NoNo099
30A:A:F212 A:A:F219 28.491712.86YesYes298
31A:A:F212 A:A:M221 28.43944.98YesYes298
32A:A:I245 A:A:L43 28.46235.71YesYes277
33A:A:I245 A:A:L45 36.77882.85YesYes278
34A:A:F312 A:A:L270 59.49232.44YesYes086
35A:A:F345 A:A:L270 40.407412.18YesYes086
36A:A:F273 A:A:F345 40.08666.43YesYes398
37A:A:F246 A:A:F273 60.15487.5NoYes099
38A:A:I348 A:A:L270 20.26434.28NoYes046
39A:A:F273 A:A:I348 20.26385.02YesNo094
40A:A:I235 A:A:W234 22.70433.52NoYes099
41A:A:Q227 A:A:W234 39.37228.76YesYes199
42B:B:C148 B:B:T102 28.75833.38NoNo068
43B:B:C149 B:B:T102 29.00053.38NoNo088
44B:B:C121 B:B:C149 14.61073.64YesNo088
45B:B:D163 B:B:H142 31.96563.78YesYes699
46B:B:D163 B:B:G144 32.27335.03YesNo098
47B:B:G144 B:B:N119 32.3356.79NoNo089
48B:B:H142 B:B:T159 15.20855.48YesYes699
49B:B:C149 B:B:I157 14.63363.27NoYes087
50A:A:Q227 B:B:N119 32.40097.92YesNo099
51A:A:I235 A:A:L282 22.16272.85NoNo099
52B:B:Q75 B:B:W99 12.48266.57YesYes199
53B:B:W332 B:B:Y59 18.02582.89YesYes198
54A:A:L282 A:A:N279 22.10056.87NoNo098
55A:A:W281 B:B:D290 16.06837.82YesYes156
56A:A:H387 A:A:Y391 73.61715.44YesYes284
57A:A:Y391 R:R:L49 38.16233.52YesYes248
58A:A:Y391 R:R:D111 34.93158.05YesYes248
59R:R:L49 R:R:R112 16.28793.64YesNo089
60B:B:F199 B:B:L190 19.16112.44YesYes595
61B:B:F199 B:B:W211 18.050813.03YesYes598
62G:G:E22 G:G:L19 12.331414.58YesYes599
63B:B:K15 G:G:L19 12.79982.82NoYes069
64B:B:E12 B:B:K15 12.24352.7NoNo046
65B:B:E12 B:B:R8 10.57432.33NoNo043
66B:B:Q9 B:B:R8 10.01792.34NoNo033
67B:B:L308 B:B:V296 11.03934.47YesYes075
68B:B:L308 B:B:W339 10.978714.81YesNo079
69B:B:C271 B:B:Y289 15.98324.03YesYes157
70B:B:C271 B:B:D290 16.18413.11YesYes156
71B:B:C294 B:B:L308 10.96663.17YesYes057
72B:B:H311 B:B:T329 12.78448.21YesYes098
73B:B:D333 B:B:H311 27.09248.82YesYes1599
74B:B:D333 B:B:N313 28.62882.69YesNo097
75B:B:N313 B:B:W332 28.93835.65NoYes079
76R:R:I108 R:R:L49 21.71065.71NoYes298
77R:R:I108 R:R:Y290 15.91627.25NoYes299
78R:R:L105 R:R:Y290 28.96737.03NoYes099
79R:R:F235 R:R:L105 22.44842.44NoNo099
80R:R:F235 R:R:L196 22.18936.09NoNo097
81R:R:L196 R:R:Y192 21.94345.86NoYes079
82R:R:H243 R:R:Y192 14.327316.33YesYes089
83R:R:F242 R:R:H243 10.67699.05YesYes078
84R:R:R112 R:R:Y290 15.94454.12NoYes099
85R:R:D111 R:R:Y52 34.77166.9YesYes087
86R:R:S135 R:R:Y52 32.05532.54YesYes077
87R:R:F104 R:R:S135 30.62262.64YesYes877
88R:R:F104 R:R:W139 29.188611.02YesYes879
89R:R:M96 R:R:W139 29.0123.49YesYes859
90R:R:L62 R:R:M96 14.50852.83NoYes075
91R:R:L62 R:R:N97 13.96414.12NoYes078
92R:R:N97 R:R:Y63 13.23213.96YesYes987
93R:R:M96 R:R:N146 11.0584.21YesNo857
94R:R:F92 R:R:N146 10.88462.42NoNo067
95R:R:F92 R:R:M149 10.70312.49NoNo064
96A:A:F238 B:B:W99 13.095712.03YesYes199
97A:A:N279 A:A:W281 22.0393.39NoYes085
98B:B:C148 B:B:L190 26.42696.35NoYes565
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9JFT
Class A
SubFamily Orphan
Type Orphan
SubType GPR65
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners Gs/Beta1/Gamma2
PDB Resolution 3.27
Date 2025-08-13
D.O.I. doi.org/10.1038/s41422-025-01092-w
Net Summary
Imin 2.41
Number of Linked Nodes 866
Number of Links 1171
Number of Hubs 242
Number of Links mediated by Hubs 836
Number of Communities 23
Number of Nodes involved in Communities 336
Number of Links involved in Communities 527
Path Summary
Number Of Nodes in MetaPath 99
Number Of Links MetaPath 98
Number of Shortest Paths 14783509
Length Of Smallest Path 3
Average Path Length 48.2695
Length of Longest Path 71
Minimum Path Strength 1.355
Average Path Strength 6.46779
Maximum Path Strength 25.67
Minimum Path Correlation 0.7
Average Path Correlation 0.998098
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.32558
Average % Of Corr. Nodes 29.0977
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 62.5597
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• fibroblast proliferation   • cell population proliferation   • cellular process   • cellular response to nitrogen compound   • cellular response to stimulus   • response to dopamine   • regulation of cellular process   • response to stimulus   • signaling   • cellular response to dopamine   • response to monoamine   • cell communication   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • signal transduction   • regulation of biological process   • G protein-coupled dopamine receptor signaling pathway   • biological regulation   • response to oxygen-containing compound   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to monoamine stimulus   • response to chemical   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • synapse   • cell junction   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • apoptotic process   • cell death   • programmed cell death   • response to pH   • response to abiotic stimulus   • response to acidic pH   • immune response   • immune system process   • positive regulation of organelle organization   • regulation of cytoskeleton organization   • regulation of cellular component organization   • regulation of actin filament-based process   • positive regulation of cellular component organization   • positive regulation of biological process   • regulation of actin filament bundle assembly   • cellular component biogenesis   • cellular component organization   • cellular component assembly   • positive regulation of actin filament bundle assembly   • actin filament bundle organization   • positive regulation of stress fiber assembly   • actin filament-based process   • cellular component organization or biogenesis   • stress fiber assembly   • positive regulation of cellular process   • regulation of actin filament organization   • actin cytoskeleton organization   • actomyosin structure organization   • positive regulation of cellular component biogenesis   • positive regulation of cytoskeleton organization   • actin filament organization   • regulation of cellular component biogenesis   • positive regulation of supramolecular fiber organization   • regulation of organelle organization   • regulation of stress fiber assembly   • organelle organization   • contractile actin filament bundle assembly   • regulation of actomyosin structure organization   • regulation of actin cytoskeleton organization   • actin filament bundle assembly   • regulation of supramolecular fiber organization   • supramolecular fiber organization   • cytoskeleton organization   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • cellular response to monoamine stimulus   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • intracellular membrane-bounded organelle   • intracellular organelle   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • G-protein beta/gamma-subunit complex binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • metal ion binding
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainA
ProteinG Protein α Sub unit
UniProtP63092
Sequence
>9JFT_Chain_A
DQRNEEKAQ REANKKIEK QLQKDKQVY RATHRLLLL GASGKSTIV 
KQMRISGIF ETKFQVDKV NFHMFDVGG QRDERRKWI QCFNDVTAI 
IFVVSSYNR LQEALNLFK SIWNNRWLR TISVILFLN KQDLLAEKV 
LAGKSKIED YFPEFARYT TPEDATPEP GEDPRVTRA KYFIRDEFL 
RISTASGDG RHYCYPHFT CAVDTENRR FNDCRDIIQ RMHLRQYEL 
LDNDDAI


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>9JFT_Chain_B
SELDQLRQE AEQLKNQIR DARKACADA TLSQITNNI DPVGRIQMR 
TRRTLRGHL AKIYAMHWG TDSRLLVSA SQDGKLIIW DSYTTNKVH 
AIPLRSSWV MTCAYAPSG NYVACGGLD NICSIYNLK TREGNVRVS 
RELAGHTGY LSCCRFLDD NQIVTSSGD TTCALWDIE TGQQTTTFT 
GHTGDVMSL SLAPDTRLF VSGACDASA KLWDVREGM CRQTFTGHE 
SDINAICFF PNGNAFATG SDDATCRLF DLRADQELM TYSHDNIIC 
GITSVSFSK SGRLLLAGY DDFNCNVWD ALKADRAGV LAGHDNRVS 
CLGVTDDGM AVATGSWDS FLKIWN


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>9JFT_Chain_G
ASIAQARKL VEQLKMEAN IDRIKVSKA AADLMAYCE AHAKEDPLL 
TPVPASENP FR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ8IYL9
Sequence
>9JFT_Chain_R
EQHDLDHYL FPIVYIFVI IVSIPANIG SLCVSFLQA KKESELGIY 
LFSLSLSDL LYALTLPLW IDYTWNKDN WTFSPALCK GSAFLMYMN 
FYSSTAFLT CIAVDRYLA VVYPLKFFF LRTRRFALM VSLSIWILE 
TIFNAVMLW EDETVVEYC NFTLCYDKY PLEKWQINL NLFRTCTGY 
AIPLVTILI CNRKVYQAV RHNKATENK EKKRIIKLL VSITVFVLC 
FTPFHVMLL IRCILEHAV NNSGKRTYT MYRITVALT SLNCVADPI 
LYCFVTETG RYI


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9BHLAOrphanOrphanGPR65Homo sapiens--Gs/β12.82025-01-22doi.org/10.1016/j.cell.2024.11.036
9BHL (No Gprot) AOrphanOrphanGPR65Homo sapiens--2.82025-01-22doi.org/10.1016/j.cell.2024.11.036
9JFTAOrphanOrphanGPR65Homo sapiens--Gs/β1/γ23.272025-08-13doi.org/10.1038/s41422-025-01092-w
9JFT (No Gprot) AOrphanOrphanGPR65Homo sapiens--3.272025-08-13doi.org/10.1038/s41422-025-01092-w




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