psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I38	R:R:N278	5.66	No	No	0	3	3
2	R:R:A39	R:R:E41	4.53	No	No	0	4	4
3	R:R:F43	R:R:V40	3.93	Yes	No	0	6	4
4	R:R:F43	R:R:T93	5.19	Yes	No	0	6	6
5	R:R:F43	R:R:L281	3.65	Yes	No	0	6	3
6	R:R:F43	R:R:I282	3.77	Yes	No	0	6	4
7	R:R:N54	R:R:S50	4.47	Yes	Yes	1	9	8
8	R:R:D82	R:R:S50	5.89	Yes	Yes	1	9	8
9	R:R:S50	R:R:S86	4.89	Yes	Yes	1	8	8
10	R:R:M285	R:R:S50	3.07	Yes	Yes	1	6	8
11	R:R:S288	R:R:S50	3.26	Yes	Yes	1	9	8
12	R:R:S50	R:R:V289	3.23	Yes	No	0	8	6
13	R:R:L51	R:R:M83	4.24	No	No	0	6	7
14	R:R:L51	R:R:M87	4.24	No	No	0	6	5
15	R:R:A79	R:R:N54	3.13	No	Yes	0	9	9
16	R:R:D82	R:R:N54	14.81	Yes	Yes	1	9	9
17	R:R:M83	R:R:N54	7.01	No	Yes	0	7	9
18	R:R:N54	R:R:P292	6.52	Yes	No	0	9	9
19	R:R:F306	R:R:L56	7.31	No	No	0	6	7
20	R:R:A296	R:R:V57	3.39	No	No	0	8	9
21	R:R:M302	R:R:V57	3.04	No	No	0	8	9
22	R:R:C76	R:R:I58	3.27	No	No	0	7	8
23	R:R:A79	R:R:I58	3.25	No	No	0	9	8
24	R:R:A60	R:R:T305	3.36	No	No	0	8	7
25	R:R:I61	R:R:L67	4.28	Yes	Yes	4	8	9
26	R:R:I61	R:R:Y72	4.84	Yes	Yes	4	8	8
27	R:R:C76	R:R:I61	3.27	No	Yes	0	7	8
28	R:R:I309	R:R:K63	7.27	No	No	0	7	5
29	R:R:N64	R:R:N66	8.17	No	No	0	7	6
30	R:R:L67	R:R:N64	12.36	Yes	No	0	9	7
31	R:R:N64	R:R:T305	8.77	No	No	0	7	7
32	R:R:H68	R:R:K65	20.96	No	No	0	8	6
33	R:R:L67	R:R:Y72	9.38	Yes	Yes	4	9	8
34	R:R:E301	R:R:L67	5.3	No	Yes	4	7	9
35	R:R:F73	R:R:H68	6.79	No	No	0	4	8
36	R:R:P70	R:R:S69	3.56	Yes	No	0	6	7
37	R:R:S69	R:R:Y72	6.36	No	Yes	0	7	8
38	R:R:P70	R:R:Y150	4.17	Yes	Yes	5	6	8
39	R:R:M154	R:R:P70	3.35	No	Yes	5	7	6
40	R:R:P70	R:R:S159	5.34	Yes	Yes	0	6	7
41	R:R:D139	R:R:M71	4.16	No	No	0	9	9
42	R:R:M71	R:R:R140	4.96	No	Yes	0	9	9
43	R:R:S299	R:R:Y72	5.09	No	Yes	0	8	8
44	R:R:E301	R:R:Y72	4.49	No	Yes	4	7	8
45	R:R:F73	R:R:S159	6.61	No	Yes	0	4	7
46	R:R:A135	R:R:F74	8.32	No	Yes	0	7	8
47	R:R:D139	R:R:F74	4.78	No	Yes	0	9	8
48	R:R:F74	R:R:I162	5.02	Yes	No	0	8	6
49	R:R:F74	R:R:I163	3.77	Yes	No	0	8	8
50	R:R:S132	R:R:S77	3.26	No	Yes	6	8	9
51	R:R:I163	R:R:S77	9.29	No	Yes	0	8	9
52	R:R:S77	R:R:W167	6.18	Yes	Yes	0	9	9
53	R:R:L78	R:R:S132	6.01	No	No	0	9	8
54	R:R:L133	R:R:L78	4.15	No	No	0	8	9
55	R:R:V80	R:R:W167	3.68	No	Yes	0	5	9
56	R:R:D82	R:R:S86	4.42	Yes	Yes	1	9	8
57	R:R:D82	R:R:S288	8.83	Yes	Yes	1	9	9
58	R:R:L84	R:R:S125	4.5	No	No	0	6	6
59	R:R:S125	R:R:V85	6.46	No	No	0	6	8
60	R:R:M285	R:R:S86	6.13	Yes	Yes	1	6	8
61	R:R:S288	R:R:S86	4.89	Yes	Yes	1	9	8
62	R:R:M87	R:R:W91	4.65	No	Yes	0	5	7
63	R:R:M121	R:R:S88	6.13	No	No	0	5	6
64	R:R:I122	R:R:S88	9.29	No	No	0	5	6
65	R:R:L281	R:R:S89	3	No	No	0	3	6
66	R:R:M285	R:R:S89	6.13	Yes	No	0	6	6
67	R:R:A90	R:R:W91	3.89	No	Yes	0	6	7
68	R:R:I94	R:R:W91	14.09	No	Yes	0	5	7
69	R:R:F118	R:R:W91	10.02	Yes	Yes	0	6	7
70	R:R:E92	R:R:I96	5.47	No	No	0	6	4
71	R:R:N101	R:R:Y97	20.93	No	No	0	4	4
72	R:R:L98	R:R:N101	4.12	No	No	7	4	4
73	R:R:H103	R:R:L98	3.86	No	No	7	3	4
74	R:R:L99	R:R:N100	8.24	No	No	0	2	3
75	R:R:H103	R:R:N101	7.65	No	No	7	3	4
76	R:R:H103	R:R:K102	7.86	No	No	0	3	2
77	R:R:F110	R:R:I106	13.82	Yes	No	0	3	5
78	R:R:F110	R:R:I114	3.77	Yes	No	0	3	4
79	R:R:H113	R:R:R112	20.31	No	No	0	4	3
80	R:R:D115	R:R:D119	5.32	No	No	0	8	4
81	R:R:I178	R:R:N116	9.91	No	No	0	4	4
82	R:R:F118	R:R:V117	3.93	Yes	No	0	6	4
83	R:R:F118	R:R:M121	4.98	Yes	No	0	6	5
84	R:R:I178	R:R:S120	6.19	No	No	0	4	5
85	R:R:C123	R:R:F177	13.97	No	No	0	5	4
86	R:R:G174	R:R:I124	3.53	No	No	0	6	4
87	R:R:V126	R:R:W251	7.36	No	Yes	0	6	7
88	R:R:C170	R:R:V127	5.12	No	No	0	7	6
89	R:R:M193	R:R:V127	3.04	No	No	0	4	6
90	R:R:A128	R:R:W167	5.19	No	Yes	0	7	9
91	R:R:F194	R:R:M130	7.46	Yes	No	8	7	7
92	R:R:M130	R:R:W251	3.49	No	Yes	8	7	7
93	R:R:C131	R:R:M197	4.86	No	No	0	5	7
94	R:R:L133	R:R:Y295	4.69	No	Yes	0	8	9
95	R:R:L134	R:R:M197	4.24	No	No	0	7	7
96	R:R:I136	R:R:R140	6.26	No	Yes	2	9	9
97	R:R:I136	R:R:Y295	3.63	No	Yes	2	9	9
98	R:R:D139	R:R:Y150	5.75	No	Yes	0	9	8
99	R:R:R140	R:R:Y205	6.17	Yes	Yes	2	9	9
100	R:R:R140	R:R:Y295	5.14	Yes	Yes	2	9	9
101	R:R:F145	R:R:Y141	20.63	Yes	Yes	9	7	8
102	R:R:L204	R:R:Y141	9.38	Yes	Yes	0	7	8
103	R:R:H207	R:R:Y141	11.98	No	Yes	9	5	8
104	R:R:M208	R:R:Y141	3.59	No	Yes	0	9	8
105	R:R:T143	R:R:Y150	8.74	No	Yes	0	9	8
106	R:R:F145	R:R:I144	6.28	Yes	No	0	7	9
107	R:R:F145	R:R:H207	19.23	Yes	No	9	7	5
108	R:R:F145	R:R:L211	7.31	Yes	No	0	7	5
109	R:R:H152	R:R:R149	11.28	No	No	0	4	5
110	R:R:H151	R:R:Y150	6.53	No	Yes	0	4	8
111	R:R:M154	R:R:Y150	7.18	No	Yes	5	7	8
112	R:R:R158	R:R:T155	3.88	No	No	0	6	8
113	R:R:G160	R:R:S159	3.71	No	Yes	0	1	7
114	R:R:C173	R:R:F169	8.38	No	No	0	4	4
115	R:R:F177	R:R:I178	5.02	No	No	0	4	4
116	R:R:S183	R:R:Y180	10.17	No	No	0	4	3
117	R:R:E182	R:R:S181	7.19	No	No	0	4	2
118	R:R:S183	R:R:V186	4.85	No	No	0	4	4
119	R:R:I191	R:R:T259	7.6	No	No	0	4	4
120	R:R:M193	R:R:M197	4.33	No	No	0	4	7
121	R:R:F194	R:R:F195	5.36	Yes	No	0	7	4
122	R:R:F194	R:R:W251	3.01	Yes	Yes	8	7	7
123	R:R:F194	R:R:F255	26.79	Yes	No	0	7	5
124	R:R:F247	R:R:L198	4.87	No	No	0	8	6
125	R:R:L200	R:R:L204	4.15	No	Yes	0	5	7
126	R:R:L201	R:R:Y205	3.52	No	Yes	0	8	9
127	R:R:F247	R:R:L201	8.53	No	No	0	8	8
128	R:R:L244	R:R:V202	4.47	No	No	0	7	5
129	R:R:L243	R:R:Y205	5.86	No	Yes	2	8	9
130	R:R:L244	R:R:Y205	5.86	No	Yes	0	7	9
131	R:R:Y205	R:R:Y295	3.97	Yes	Yes	2	9	9
132	R:R:F209	R:R:R213	6.41	Yes	No	0	6	5
133	R:R:F209	R:R:G236	3.01	Yes	No	0	6	8
134	R:R:F209	R:R:V240	3.93	Yes	No	0	6	8
135	R:R:H215	R:R:L211	5.14	No	No	0	7	5
136	R:R:R213	R:R:S233	6.59	No	No	0	5	6
137	R:R:A220	R:R:R231	6.91	No	No	0	4	4
138	R:R:L222	R:R:P223	4.93	No	No	0	3	2
139	R:R:M234	R:R:V238	3.04	No	No	0	5	6
140	R:R:M242	R:R:T239	4.52	No	No	0	6	9
141	R:R:I294	R:R:L243	4.28	No	No	2	9	8
142	R:R:L243	R:R:Y295	5.86	No	Yes	2	8	9
143	R:R:F247	R:R:W251	8.02	No	Yes	0	8	7
144	R:R:C250	R:R:N287	9.45	No	No	0	8	9
145	R:R:I284	R:R:W251	10.57	No	Yes	0	7	7
146	R:R:N287	R:R:W251	9.04	No	Yes	0	9	7
147	R:R:P253	R:R:Y280	5.56	No	Yes	0	9	5
148	R:R:F254	R:R:F255	5.36	Yes	No	0	5	5
149	R:R:F254	R:R:L258	10.96	Yes	No	0	5	4
150	R:R:F254	R:R:F277	4.29	Yes	No	0	5	4
151	R:R:F254	R:R:I284	6.28	Yes	No	0	5	7
152	R:R:L256	R:R:T259	4.42	No	No	0	4	4
153	R:R:F273	R:R:L256	8.53	No	No	0	4	4
154	R:R:H257	R:R:L258	3.86	Yes	No	0	4	4
155	R:R:H257	R:R:M274	10.51	Yes	No	0	4	1
156	R:R:F277	R:R:H257	15.84	No	Yes	0	4	4
157	R:R:H257	R:R:Y280	3.27	Yes	Yes	0	4	5
158	R:R:L260	R:R:S263	3	Yes	No	3	3	4
159	R:R:C264	R:R:L260	4.76	Yes	Yes	3	3	3
160	R:R:C270	R:R:L260	3.17	No	Yes	3	2	3
161	R:R:F273	R:R:L260	6.09	No	Yes	0	4	3
162	R:R:C264	R:R:S263	3.44	Yes	No	3	3	4
163	R:R:C264	R:R:N267	6.3	Yes	No	3	3	3
164	R:R:C264	R:R:C270	7.28	Yes	No	3	3	2
165	R:R:P265	R:R:Q266	6.32	No	No	0	2	1
166	R:R:C270	R:R:N267	6.3	No	No	3	2	3
167	R:R:R272	R:R:Y269	4.12	No	No	0	4	4
168	R:R:F273	R:R:Y280	16.5	No	Yes	0	4	5
169	R:R:H276	R:R:S275	6.97	No	No	0	3	2
170	R:R:H276	R:R:M279	6.57	No	No	0	3	4
171	R:R:H276	R:R:Y280	8.71	No	Yes	0	3	5
172	R:R:M279	R:R:N278	9.82	No	No	0	4	3
173	R:R:M285	R:R:S288	6.13	Yes	Yes	1	6	9
174	R:R:D291	R:R:N287	10.77	No	No	0	9	9
175	R:R:L293	R:R:M290	4.24	No	No	0	6	6
176	R:R:D291	R:R:P292	3.22	No	No	0	9	9
177	R:R:I294	R:R:Y295	6.04	No	Yes	2	9	9
178	R:R:F297	R:R:R303	13.9	No	No	0	6	9
179	R:R:R298	R:R:R303	4.26	No	No	0	8	9
180	R:R:Q300	R:R:R303	11.68	No	No	0	5	9
181	R:R:F306	R:R:K307	8.69	No	No	0	6	5
182	R:R:L46	R:R:V289	2.98	No	No	0	6	6
183	R:R:L134	R:R:V138	2.98	No	No	0	7	7
184	R:R:L244	R:R:V240	2.98	No	No	0	7	8
185	R:R:N54	R:R:V57	2.96	Yes	No	0	9	9
186	R:R:L198	R:R:T248	2.95	No	No	0	6	5
187	R:R:L211	R:R:T214	2.95	No	No	0	5	5
188	R:R:I55	R:R:M83	2.92	No	No	0	5	7
189	R:R:M130	R:R:M193	2.89	No	No	0	7	4
190	R:R:M261	R:R:M274	2.89	No	No	0	4	1
191	R:R:I94	R:R:L98	2.85	No	No	0	5	4
192	R:R:A107	R:R:F110	2.77	No	Yes	0	6	3
193	R:R:A252	R:R:F194	2.77	No	Yes	0	5	7
194	R:R:A237	R:R:F209	2.77	No	Yes	0	7	6
195	R:R:E308	R:R:K63	2.7	No	No	0	5	5
196	R:R:N267	R:R:Q266	2.64	No	No	0	3	1
197	R:R:F43	R:R:V42	2.62	Yes	No	0	6	5
198	R:R:F177	R:R:V186	2.62	No	No	0	4	4
199	R:R:A81	R:R:W167	2.59	No	Yes	0	8	9
200	R:R:F118	R:R:T95	2.59	Yes	No	0	6	4
201	R:R:V142	R:R:Y150	2.52	No	Yes	0	6	8
202	R:R:M208	R:R:R140	2.48	No	Yes	0	9	9
203	R:R:F297	R:R:L293	2.44	No	No	0	6	6
204	R:R:I153	R:R:Y146	2.42	No	No	0	6	6
205	R:R:F145	R:R:Y146	2.06	Yes	No	0	7	6
206	R:R:C123	R:R:G174	1.96	No	No	0	5	6
207	R:R:A164	R:R:G165	1.95	No	No	0	4	4
208	R:R:A168	R:R:G165	1.95	No	No	0	3	4
209	R:R:G172	R:R:T171	1.82	No	No	0	3	3
210	R:R:G245	R:R:T248	1.82	No	No	0	5	5
211	R:R:G172	R:R:I175	1.76	No	No	0	3	3
212	R:R:G47	R:R:M285	1.75	No	Yes	0	6	6
213	R:R:A81	R:R:S129	1.71	No	No	0	8	9
214	R:R:A156	R:R:S159	1.71	No	Yes	0	2	7
215	R:R:C250	R:R:V246	1.71	No	No	0	8	6
216	R:R:A296	R:R:V75	1.7	No	No	0	8	8
217	R:R:G236	R:R:Q235	1.64	No	No	0	8	8
218	R:R:C311	R:R:I310	1.64	No	No	0	6	5
219	R:R:S125	R:R:S88	1.63	No	No	0	6	6
220	R:R:A60	R:R:I309	1.62	No	No	0	8	7
221	R:R:V176	R:R:V186	1.6	No	No	0	5	4
222	R:R:C189	R:R:L188	1.59	No	No	0	4	4
223	R:R:T248	R:R:V249	1.59	No	No	0	5	5
224	R:R:A137	R:R:L201	1.58	No	No	0	9	8
225	R:R:A137	R:R:L204	1.58	No	Yes	0	9	7
226	R:R:I166	R:R:S77	1.55	No	Yes	6	6	9
227	R:R:I166	R:R:S132	1.55	No	No	6	6	8
228	R:R:I49	R:R:V289	1.54	No	No	0	5	6
229	R:R:I58	R:R:V62	1.54	No	No	0	8	3
230	R:R:I61	R:R:V62	1.54	Yes	No	0	8	3
231	R:R:I206	R:R:V202	1.54	No	No	0	4	5
232	R:R:I206	R:R:V240	1.54	No	No	0	4	8
233	R:R:I49	R:R:T45	1.52	No	No	0	5	3
234	R:R:I114	R:R:T95	1.52	No	No	0	4	4
235	R:R:M290	R:R:V246	1.52	No	No	0	6	6
236	R:R:M234	R:R:T232	1.51	No	No	0	5	5
237	R:R:L204	R:R:S203	1.5	Yes	No	0	7	4
238	R:R:L44	R:R:V40	1.49	No	No	0	5	4
239	R:R:L190	R:R:V127	1.49	No	No	0	5	6
240	R:R:D119	R:R:S120	1.47	No	No	0	4	5
241	R:R:D108	R:R:V111	1.46	No	No	0	2	3
242	R:R:I187	R:R:M261	1.46	No	No	0	5	4
243	R:R:I309	R:R:L56	1.43	No	No	0	7	7
244	R:R:I187	R:R:L262	1.43	No	No	0	5	3
245	R:R:I206	R:R:L210	1.43	No	No	0	4	3
246	R:R:I96	R:R:N100	1.42	No	No	0	4	3
247	R:R:Q235	R:R:T232	1.42	No	No	0	8	5
248	R:R:E92	R:R:T93	1.41	No	No	0	6	6
249	R:R:E53	R:R:I49	1.37	No	No	0	8	5
250	R:R:R272	R:R:S275	1.32	No	No	0	4	2
251	R:R:R231	R:R:V216	1.31	No	No	0	4	6
252	R:R:R157	R:R:T155	1.29	No	No	0	4	8
253	R:R:S183	R:R:Y185	1.27	No	No	0	4	1
254	R:R:F306	R:R:I310	1.26	No	No	0	6	5
255	R:R:I153	R:R:R149	1.25	No	No	0	6	5
256	R:R:T184	R:R:Y185	1.25	No	No	0	3	1
257	R:R:L179	R:R:Y180	1.17	No	No	0	3	3
258	R:R:F110	R:R:H113	1.13	Yes	No	0	3	4
259	R:R:H215	R:R:R218	1.13	No	No	0	7	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F43	3.832	5	0	6
2	R:R:S50	4.135	6	1	8
3	R:R:N54	6.48333	6	1	9
4	R:R:I61	3.4825	4	4	8
5	R:R:L67	7.83	4	4	9
6	R:R:P70	4.105	4	5	6
7	R:R:Y72	6.032	5	4	8
8	R:R:F74	5.4725	4	0	8
9	R:R:S77	5.07	4	6	9
10	R:R:D82	8.4875	4	1	9
11	R:R:S86	5.0825	4	1	8
12	R:R:W91	8.1625	4	0	7
13	R:R:F110	5.3725	4	0	3
14	R:R:F118	5.38	4	0	6
15	R:R:R140	5.002	5	2	9
16	R:R:Y141	11.395	4	9	8
17	R:R:F145	11.102	5	9	7
18	R:R:Y150	5.815	6	5	8
19	R:R:S159	4.3425	4	0	7
20	R:R:W167	4.41	4	0	9
21	R:R:F194	9.078	5	8	7
22	R:R:L204	4.1525	4	0	7
23	R:R:Y205	5.076	5	2	9
24	R:R:F209	4.03	4	0	6
25	R:R:W251	6.915	6	8	7
26	R:R:F254	6.7225	4	0	5
27	R:R:H257	8.37	4	0	4
28	R:R:L260	4.255	4	3	3
29	R:R:C264	5.445	4	3	3
30	R:R:Y280	8.51	4	0	5
31	R:R:M285	4.642	5	1	6
32	R:R:S288	5.7775	4	1	9
33	R:R:Y295	4.88833	6	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F43	R:R:L281	22.315	3.65	Yes	No	0	6	3
2	R:R:L281	R:R:S89	24.4742	3	No	No	0	3	6
3	R:R:M285	R:R:S89	26.6094	6.13	Yes	No	0	6	6
4	R:R:M285	R:R:S50	30.3821	3.07	Yes	Yes	1	6	8
5	R:R:N54	R:R:S50	46.5484	4.47	Yes	Yes	1	9	8
6	R:R:N54	R:R:P292	95.9705	6.52	Yes	No	0	9	9
7	R:R:D291	R:R:P292	96.1711	3.22	No	No	0	9	9
8	R:R:D291	R:R:N287	96.4601	10.77	No	No	0	9	9
9	R:R:N287	R:R:W251	100	9.04	No	Yes	0	9	7
10	R:R:I284	R:R:W251	93.8915	10.57	No	Yes	0	7	7
11	R:R:F254	R:R:I284	92.7838	6.28	Yes	No	0	5	7
12	R:R:F254	R:R:L258	48.8843	10.96	Yes	No	0	5	4
13	R:R:H257	R:R:L258	47.4233	3.86	Yes	No	0	4	4
14	R:R:H257	R:R:Y280	78.8249	3.27	Yes	Yes	0	4	5
15	R:R:H276	R:R:Y280	24.8836	8.71	No	Yes	0	3	5
16	R:R:H276	R:R:M279	10.7561	6.57	No	No	0	3	4
17	R:R:F254	R:R:F277	48.8441	4.29	Yes	No	0	5	4
18	R:R:F277	R:R:H257	47.4233	15.84	No	Yes	0	4	4
19	R:R:F43	R:R:T93	11.318	5.19	Yes	No	0	6	6
20	R:R:S50	R:R:V289	11.31	3.23	Yes	No	0	8	6
21	R:R:M83	R:R:N54	56.6463	7.01	No	Yes	0	7	9
22	R:R:L51	R:R:M83	52.8415	4.24	No	No	0	6	7
23	R:R:L51	R:R:M87	50.9151	4.24	No	No	0	6	5
24	R:R:A79	R:R:N54	70.3163	3.13	No	Yes	0	9	9
25	R:R:F306	R:R:L56	12.5462	7.31	No	No	0	6	7
26	R:R:I309	R:R:L56	15.6446	1.43	No	No	0	7	7
27	R:R:A60	R:R:I309	24.8435	1.62	No	No	0	8	7
28	R:R:A60	R:R:T305	27.8777	3.36	No	No	0	8	7
29	R:R:N64	R:R:T305	30.8958	8.77	No	No	0	7	7
30	R:R:L67	R:R:N64	36.8839	12.36	Yes	No	0	9	7
31	R:R:I61	R:R:L67	33.9621	4.28	Yes	Yes	4	8	9
32	R:R:C76	R:R:I61	33.9862	3.27	No	Yes	0	7	8
33	R:R:C76	R:R:I58	34.532	3.27	No	No	0	7	8
34	R:R:A79	R:R:I58	69.5136	3.25	No	No	0	9	8
35	R:R:I61	R:R:V62	33.9862	1.54	Yes	No	0	8	3
36	R:R:I58	R:R:V62	34.532	1.54	No	No	0	8	3
37	R:R:I61	R:R:Y72	32.2764	4.84	Yes	Yes	4	8	8
38	R:R:P70	R:R:S159	14.1997	5.34	Yes	Yes	0	6	7
39	R:R:P70	R:R:Y150	34.2992	4.17	Yes	Yes	5	6	8
40	R:R:D139	R:R:Y150	35.5755	5.75	No	Yes	0	9	8
41	R:R:D139	R:R:M71	27.7412	4.16	No	No	0	9	9
42	R:R:M71	R:R:R140	28.8891	4.96	No	Yes	0	9	9
43	R:R:R140	R:R:Y205	26.5773	6.17	Yes	Yes	2	9	9
44	R:R:L201	R:R:Y205	58.5568	3.52	No	Yes	0	8	9
45	R:R:F247	R:R:L201	77.1954	8.53	No	No	0	8	8
46	R:R:F247	R:R:W251	80.7272	8.02	No	Yes	0	8	7
47	R:R:P70	R:R:S69	34.9334	3.56	Yes	No	0	6	7
48	R:R:D139	R:R:F74	18.165	4.78	No	Yes	0	9	8
49	R:R:F74	R:R:I163	11.5669	3.77	Yes	No	0	8	8
50	R:R:Y205	R:R:Y295	17.7717	3.97	Yes	Yes	2	9	9
51	R:R:L133	R:R:Y295	15.9978	4.69	No	Yes	0	8	9
52	R:R:L133	R:R:L78	14.2398	4.15	No	No	0	8	9
53	R:R:L78	R:R:S132	12.7709	6.01	No	No	0	9	8
54	R:R:S132	R:R:S77	10.0417	3.26	No	Yes	6	8	9
55	R:R:S77	R:R:W167	14.8017	6.18	Yes	Yes	0	9	9
56	R:R:M87	R:R:W91	48.9725	4.65	No	Yes	0	5	7
57	R:R:F118	R:R:W91	32.8383	10.02	Yes	Yes	0	6	7
58	R:R:F118	R:R:M121	13.6057	4.98	Yes	No	0	6	5
59	R:R:M121	R:R:S88	11.3903	6.13	No	No	0	5	6
60	R:R:I94	R:R:W91	13.6218	14.09	No	Yes	0	5	7
61	R:R:I94	R:R:L98	11.3903	2.85	No	No	0	5	4
62	R:R:F110	R:R:I114	11.3903	3.77	Yes	No	0	3	4
63	R:R:I114	R:R:T95	13.6137	1.52	No	No	0	4	4
64	R:R:F118	R:R:T95	15.7489	2.59	Yes	No	0	6	4
65	R:R:M130	R:R:M193	19.8908	2.89	No	No	0	7	4
66	R:R:M130	R:R:W251	17.7637	3.49	No	Yes	8	7	7
67	R:R:M193	R:R:M197	10.0738	4.33	No	No	0	4	7
68	R:R:F145	R:R:Y141	18.9035	20.63	Yes	Yes	9	7	8
69	R:R:L204	R:R:Y141	16.3188	9.38	Yes	Yes	0	7	8
70	R:R:A137	R:R:L204	19.0641	1.58	No	Yes	0	9	7
71	R:R:A137	R:R:L201	20.7256	1.58	No	No	0	9	8
72	R:R:M208	R:R:R140	10.8123	2.48	No	Yes	0	9	9
73	R:R:F273	R:R:L256	10.7481	8.53	No	No	0	4	4
74	R:R:F273	R:R:Y280	48.9806	16.5	No	Yes	0	4	5
75	R:R:L244	R:R:Y205	28.7125	5.86	No	Yes	0	7	9
76	R:R:F209	R:R:V240	16.5596	3.93	Yes	No	0	6	8
77	R:R:L244	R:R:V240	21.6969	2.98	No	No	0	7	8
78	R:R:C250	R:R:N287	16.1743	9.45	No	No	0	8	9
79	R:R:H257	R:R:M274	14.3121	10.51	Yes	No	0	4	1
80	R:R:F273	R:R:L260	35.3106	6.09	No	Yes	0	4	3
81	R:R:C264	R:R:L260	14.1515	4.76	Yes	Yes	3	3	3
82	R:R:C270	R:R:L260	14.1596	3.17	No	Yes	3	2	3
83	R:R:C264	R:R:N267	10.6598	6.3	Yes	No	3	3	3
84	R:R:C270	R:R:N267	10.6357	6.3	No	No	3	2	3
85	R:R:N267	R:R:Q266	14.2158	2.64	No	No	0	3	1
86	R:R:H276	R:R:S275	10.7561	6.97	No	No	0	3	2
87	R:R:C250	R:R:V246	14.2077	1.71	No	No	0	8	6
88	R:R:M290	R:R:V246	12.2251	1.52	No	No	0	6	6
89	R:R:L293	R:R:M290	10.2264	4.24	No	No	0	6	6
90	R:R:M261	R:R:M274	10.7561	2.89	No	No	0	4	1
91	R:R:S69	R:R:Y72	35.0056	6.36	No	Yes	0	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9K3H_nogp

PDB Summary
PDB	9K3H_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3
Number of Linked Nodes	245
Number of Links	259
Number of Hubs	33
Number of Links mediated by Hubs	123
Number of Communities	9
Number of Nodes involved in Communities	36
Number of Links involved in Communities	47

Path Summary
Number Of Nodes in MetaPath	92
Number Of Links MetaPath	91
Number of Shortest Paths	32604
Length Of Smallest Path	3
Average Path Length	13.9874
Length of Longest Path	29
Minimum Path Strength	1.26
Average Path Strength	5.8699
Maximum Path Strength	17.125
Minimum Path Correlation	0.7
Average Path Correlation	0.944858
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	59.8129
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.1855
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P33032
Sequence	>9K3H_nogp_Chain_R I A V E V F L T L G V I S L L E N I L V I G A I V K N K N L H S P M Y F F V C S L A V A D M L V S M S S A W E T I T I Y L L N N K H L V I A D A F V R H I D N V F D S M I C I S V V A S M C S L L A I A V D R Y V T I F Y A L R Y H H I M T A R R S G A I I A G I W A F C T G C G I V F I L Y S E S T Y V I L C L I S M F F A M L F L L V S L Y I H M F L L A R T H V K R I A A L P G A S R T S M Q G A V T V T M L L G V F T V C W A P F F L H L T L M L S C P Q N L Y C S R F M S H F N M Y L I L I M C N S V M D P L I Y A F R S Q E M R K T F K E I I C C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8INR	A	Peptide	Melanocortin	MC₅	Homo sapiens	α-MSH	Ca	chim(NtGi1-Gs)/β1/γ2	2.73	2023-09-20	doi.org/10.1038/s41421-023-00586-4
	8INR (No Gprot)	A	Peptide	Melanocortin	MC₅	Homo sapiens	α-MSH	Ca		2.73	2023-09-20	doi.org/10.1038/s41421-023-00586-4
	8IOD	A	Peptide	Melanocortin	MC₅	Homo sapiens	PG-901	Ca	chim(NtGi1-Gs)/β1/γ2	2.59	2023-09-20	doi.org/10.1038/s41421-023-00586-4
	8IOD (No Gprot)	A	Peptide	Melanocortin	MC₅	Homo sapiens	PG-901	Ca		2.59	2023-09-20	doi.org/10.1038/s41421-023-00586-4
	9K3H	A	Peptide	Melanocortin	MC₅	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.86	2025-08-06	doi.org/10.1016/j.str.2025.03.004
	9K3H (No Gprot)	A	Peptide	Melanocortin	MC₅	Homo sapiens	-	-		2.86	2025-08-06	doi.org/10.1016/j.str.2025.03.004

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9K3H_nogp.zip

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