psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:F3	L:L:P5	15.89	Yes	No	7	0	0
2	L:L:F3	R:R:Q37	5.86	Yes	No	0	0	1
3	L:L:F3	R:R:D103	7.17	Yes	No	7	0	4
4	L:L:F3	R:R:N104	4.83	Yes	No	0	0	4
5	L:L:F3	R:R:T307	6.49	Yes	No	0	0	4
6	L:L:Q4	R:R:I293	5.49	No	No	0	0	4
7	L:L:P5	R:R:D103	4.83	No	No	7	0	4
8	L:L:Q6	L:L:R7	5.84	No	Yes	0	0	0
9	L:L:Q6	R:R:W109	2.19	No	Yes	0	0	8
10	L:L:Q6	R:R:Q123	3.84	No	No	0	0	7
11	L:L:R7	R:R:S176	5.27	Yes	No	0	0	6
12	L:L:R7	R:R:E205	10.47	Yes	Yes	0	0	4
13	L:L:R7	R:R:T217	2.59	Yes	No	0	0	5
14	L:L:R7	R:R:L290	2.43	Yes	No	0	0	5
15	L:L:F8	R:R:V127	3.93	No	No	0	0	7
16	L:L:F8	R:R:L220	2.44	No	Yes	1	0	5
17	L:L:F8	R:R:W287	5.01	No	Yes	1	0	7
18	R:R:F32	R:R:L30	2.44	No	No	8	5	2
19	R:R:F189	R:R:L30	3.65	No	No	8	1	2
20	R:R:H188	R:R:T31	4.11	Yes	No	0	1	4
21	R:R:F189	R:R:F32	4.29	No	No	8	1	5
22	R:R:F32	R:R:V191	5.24	No	No	0	5	4
23	R:R:S33	R:R:T107	4.8	No	No	0	5	4
24	R:R:Y35	R:R:Y36	2.98	Yes	No	0	4	4
25	R:R:M190	R:R:Y35	2.39	No	Yes	2	2	4
26	R:R:D192	R:R:Y35	21.84	Yes	Yes	2	5	4
27	R:R:Y198	R:R:Y35	19.86	Yes	Yes	2	2	4
28	R:R:I106	R:R:Y36	3.63	No	No	0	4	4
29	R:R:H38	R:R:Q37	6.18	Yes	No	0	4	1
30	R:R:Q37	R:R:T107	4.25	No	No	0	1	4
31	R:R:H38	R:R:V42	8.3	Yes	Yes	5	4	4
32	R:R:H38	R:R:V308	4.15	Yes	No	0	4	3
33	R:R:H38	R:R:Y309	8.71	Yes	No	5	4	1
34	R:R:P41	R:R:T39	5.25	No	No	0	1	3
35	R:R:T39	R:R:V42	3.17	No	Yes	0	3	4
36	R:R:P41	R:R:S40	3.56	No	No	0	1	2
37	R:R:F46	R:R:V42	2.62	Yes	Yes	5	5	4
38	R:R:V42	R:R:Y309	6.31	Yes	No	5	4	1
39	R:R:F46	R:R:M45	6.22	Yes	No	0	5	4
40	R:R:F46	R:R:Y309	2.06	Yes	No	5	5	1
41	R:R:F46	R:R:P312	7.22	Yes	No	0	5	3
42	R:R:I47	R:R:L101	4.28	No	No	0	5	7
43	R:R:A49	R:R:W316	3.89	No	Yes	0	5	5
44	R:R:M97	R:R:Y50	3.59	Yes	No	0	7	7
45	R:R:W316	R:R:Y50	8.68	Yes	No	0	5	7
46	R:R:L52	R:R:L55	5.54	No	No	0	5	5
47	R:R:I53	R:R:W316	3.52	No	Yes	6	7	5
48	R:R:F320	R:R:I53	5.02	No	No	6	5	7
49	R:R:I53	R:R:S323	4.64	No	Yes	6	7	7
50	R:R:F54	R:R:M58	11.2	No	No	0	6	6
51	R:R:F54	R:R:I94	2.51	No	No	0	6	5
52	R:R:F54	R:R:M97	8.71	No	Yes	0	6	7
53	R:R:L56	R:R:S323	3	No	Yes	0	5	7
54	R:R:C57	R:R:S323	3.44	No	Yes	0	8	7
55	R:R:G60	R:R:V59	1.84	No	No	0	8	5
56	R:R:D89	R:R:N61	4.04	Yes	Yes	3	9	9
57	R:R:L90	R:R:N61	9.61	No	Yes	0	7	9
58	R:R:N61	R:R:P326	4.89	Yes	No	3	9	9
59	R:R:P326	R:R:V64	1.77	No	No	0	9	9
60	R:R:A86	R:R:C65	1.81	No	No	0	9	7
61	R:R:F66	R:R:I67	6.28	No	No	0	4	7
62	R:R:F66	R:R:K70	2.48	No	No	0	4	5
63	R:R:F336	R:R:I67	5.02	Yes	No	0	8	7
64	R:R:L83	R:R:V68	5.96	No	No	0	6	6
65	R:R:F336	R:R:V68	3.93	Yes	No	0	8	6
66	R:R:H73	R:R:N71	7.65	No	No	0	5	5
67	R:R:M74	R:R:N71	7.01	No	No	0	7	5
68	R:R:H75	R:R:R72	12.41	No	No	0	7	6
69	R:R:M74	R:R:N79	5.61	No	No	0	7	8
70	R:R:N79	R:R:T76	8.77	No	No	0	8	7
71	R:R:E140	R:R:V77	2.85	No	No	0	8	7
72	R:R:E140	R:R:T78	4.23	No	No	0	8	8
73	R:R:F336	R:R:N79	4.83	Yes	No	0	8	8
74	R:R:F81	R:R:M80	4.98	Yes	No	0	8	5
75	R:R:A158	R:R:M80	3.22	No	No	0	7	5
76	R:R:A136	R:R:F81	2.77	No	Yes	0	7	8
77	R:R:F81	R:R:I137	8.79	Yes	No	0	8	9
78	R:R:F336	R:R:I82	2.51	Yes	No	0	8	8
79	R:R:N84	R:R:T133	5.85	No	No	0	9	8
80	R:R:I162	R:R:N84	7.08	No	No	11	8	9
81	R:R:N84	R:R:W166	4.52	No	No	11	9	9
82	R:R:L85	R:R:T133	4.42	Yes	No	0	9	8
83	R:R:L134	R:R:L85	4.15	No	Yes	0	8	9
84	R:R:L85	R:R:N325	4.12	Yes	No	12	9	9
85	R:R:L85	R:R:Y329	2.34	Yes	No	12	9	9
86	R:R:S130	R:R:S88	4.89	No	No	3	9	8
87	R:R:D89	R:R:S322	5.89	Yes	No	0	9	9
88	R:R:D89	R:R:P326	8.05	Yes	No	3	9	9
89	R:R:G93	R:R:V92	3.68	No	Yes	0	7	7
90	R:R:C96	R:R:V92	3.42	No	Yes	0	7	7
91	R:R:S126	R:R:V92	4.85	No	Yes	0	8	7
92	R:R:S322	R:R:V92	4.85	No	Yes	0	9	7
93	R:R:F95	R:R:I94	5.02	No	No	0	6	5
94	R:R:F95	R:R:V122	2.62	No	No	0	6	5
95	R:R:C96	R:R:Q123	3.05	No	No	0	7	7
96	R:R:C96	R:R:F319	4.19	No	No	0	7	7
97	R:R:M97	R:R:P98	13.42	Yes	No	0	7	8
98	R:R:F319	R:R:T100	6.49	No	No	0	7	6
99	R:R:N104	R:R:P312	6.52	No	No	0	4	3
100	R:R:G108	R:R:I106	1.76	No	No	0	4	4
101	R:R:I106	R:R:P110	3.39	No	No	0	4	3
102	R:R:G108	R:R:T107	1.82	No	No	0	4	4
103	R:R:F111	R:R:W109	17.04	No	Yes	0	7	8
104	R:R:C116	R:R:W109	11.75	No	Yes	4	9	8
105	R:R:S119	R:R:W109	2.47	No	Yes	0	5	8
106	R:R:C203	R:R:W109	11.75	Yes	Yes	4	9	8
107	R:R:F111	R:R:P110	11.56	No	No	0	7	3
108	R:R:F111	R:R:T115	5.19	No	No	0	7	6
109	R:R:D112	R:R:N113	6.73	No	No	0	8	3
110	R:R:A114	R:R:D112	4.63	No	No	0	1	8
111	R:R:D112	R:R:T115	5.78	No	No	0	8	6
112	R:R:N113	R:R:V182	2.96	No	No	0	3	5
113	R:R:C116	R:R:L180	3.17	No	No	4	9	5
114	R:R:C116	R:R:C203	7.28	No	Yes	4	9	9
115	R:R:K117	R:R:L180	4.23	No	No	0	7	5
116	R:R:G120	R:R:S119	1.86	No	No	0	5	5
117	R:R:G120	R:R:Q123	4.93	No	No	0	5	7
118	R:R:L121	R:R:M173	2.83	No	Yes	0	6	7
119	R:R:A177	R:R:L121	6.3	No	No	0	5	6
120	R:R:M125	R:R:V122	4.56	No	No	0	6	5
121	R:R:G124	R:R:M173	5.24	No	Yes	0	5	7
122	R:R:L170	R:R:M125	7.07	No	No	0	4	6
123	R:R:S126	R:R:V127	3.23	No	No	0	8	7
124	R:R:V127	R:R:W283	3.68	No	Yes	0	7	8
125	R:R:S128	R:R:W132	2.47	Yes	Yes	1	6	6
126	R:R:M173	R:R:S128	3.07	Yes	Yes	0	7	6
127	R:R:H223	R:R:S128	2.79	Yes	Yes	1	5	6
128	R:R:I224	R:R:S128	4.64	Yes	Yes	1	6	6
129	R:R:A129	R:R:W166	7.78	No	No	0	7	9
130	R:R:I224	R:R:V131	4.61	Yes	No	0	6	8
131	R:R:P228	R:R:V131	3.53	Yes	No	0	9	8
132	R:R:F279	R:R:V131	2.62	No	No	0	9	8
133	R:R:V135	R:R:W132	2.45	Yes	Yes	1	7	6
134	R:R:I165	R:R:W132	7.05	No	Yes	0	7	6
135	R:R:H223	R:R:W132	15.87	Yes	Yes	1	5	6
136	R:R:P228	R:R:W132	6.76	Yes	Yes	1	9	6
137	R:R:P228	R:R:V135	3.53	Yes	Yes	1	9	7
138	R:R:I232	R:R:V135	6.14	No	Yes	1	8	7
139	R:R:A138	R:R:I232	3.25	No	No	1	9	8
140	R:R:A138	R:R:Y236	4	No	Yes	1	9	9
141	R:R:C144	R:R:E140	3.04	No	No	0	8	8
142	R:R:R141	R:R:Y236	5.14	No	Yes	0	9	9
143	R:R:R141	R:R:Y329	2.06	No	No	0	9	9
144	R:R:F142	R:R:V146	10.49	Yes	No	0	8	6
145	R:R:F142	R:R:M235	11.2	Yes	No	0	8	7
146	R:R:F142	R:R:I239	7.54	Yes	No	0	8	8
147	R:R:R143	R:R:R150	6.4	No	No	0	5	4
148	R:R:H147	R:R:V146	5.54	No	No	0	6	6
149	R:R:K242	R:R:V146	3.04	No	No	0	4	6
150	R:R:H147	R:R:R150	24.83	No	No	0	6	4
151	R:R:K157	R:R:L153	4.23	No	No	0	5	6
152	R:R:K157	R:R:T154	6.01	No	No	0	5	7
153	R:R:I162	R:R:W166	2.35	No	No	11	8	9
154	R:R:H223	R:R:I172	7.95	Yes	No	0	5	5
155	R:R:L220	R:R:M173	4.24	Yes	Yes	0	5	7
156	R:R:C174	R:R:P175	1.88	No	No	0	4	7
157	R:R:S176	R:R:Y216	8.9	No	No	0	6	6
158	R:R:T179	R:R:W207	20.62	No	Yes	0	5	5
159	R:R:C203	R:R:L180	3.17	Yes	No	4	9	5
160	R:R:A206	R:R:T181	3.36	No	No	0	3	5
161	R:R:C203	R:R:V182	5.12	Yes	No	0	9	5
162	R:R:T183	R:R:W204	3.64	No	Yes	0	3	3
163	R:R:E186	R:R:R184	12.79	No	No	0	1	1
164	R:R:E185	R:R:H188	8.62	No	Yes	9	1	1
165	R:R:E185	R:R:L200	6.63	No	No	9	1	1
166	R:R:E186	R:R:H187	4.92	No	No	0	1	3
167	R:R:H187	R:R:H188	2.39	No	Yes	0	3	1
168	R:R:H188	R:R:L200	2.57	Yes	No	9	1	1
169	R:R:M190	R:R:Y198	2.39	No	Yes	2	2	2
170	R:R:N195	R:R:V191	2.96	No	No	0	6	4
171	R:R:D192	R:R:R194	10.72	Yes	No	2	5	4
172	R:R:D192	R:R:R196	2.38	Yes	Yes	2	5	6
173	R:R:D192	R:R:Y198	2.3	Yes	Yes	2	5	2
174	R:R:R194	R:R:R196	8.53	No	Yes	2	4	6
175	R:R:R194	R:R:Y198	4.12	No	Yes	2	4	2
176	R:R:R196	R:R:S197	2.64	Yes	No	0	6	3
177	R:R:R196	R:R:Y198	6.17	Yes	Yes	2	6	2
178	R:R:P199	R:R:Y201	11.13	No	No	0	4	3
179	R:R:A206	R:R:W204	5.19	No	Yes	0	3	3
180	R:R:E205	R:R:W207	3.27	Yes	Yes	0	4	5
181	R:R:E205	R:R:R213	11.63	Yes	No	0	4	4
182	R:R:P208	R:R:W207	4.05	No	Yes	0	3	5
183	R:R:M212	R:R:W207	6.98	No	Yes	0	3	5
184	R:R:E209	R:R:M212	4.06	No	No	0	2	3
185	R:R:M212	R:R:V215	4.56	No	No	0	3	4
186	R:R:D294	R:R:R213	8.34	No	No	0	5	4
187	R:R:R214	R:R:Y295	12.35	No	No	0	3	4
188	R:R:L220	R:R:Y216	5.86	Yes	No	0	5	6
189	R:R:D294	R:R:T217	10.12	No	No	0	5	5
190	R:R:L220	R:R:W287	2.28	Yes	Yes	1	5	7
191	R:R:F221	R:R:Y225	3.09	Yes	Yes	1	6	8
192	R:R:F221	R:R:W287	13.03	Yes	Yes	1	6	7
193	R:R:F221	R:R:L291	2.44	Yes	No	0	6	6
194	R:R:H223	R:R:I224	7.95	Yes	Yes	1	5	6
195	R:R:I224	R:R:W287	2.35	Yes	Yes	1	6	7
196	R:R:L229	R:R:Y225	4.69	No	Yes	0	6	8
197	R:R:W283	R:R:Y225	1.93	Yes	Yes	1	8	8
198	R:R:L284	R:R:Y225	5.86	No	Yes	0	5	8
199	R:R:W287	R:R:Y225	6.75	Yes	Yes	1	7	8
200	R:R:A227	R:R:P228	1.87	No	Yes	0	5	9
201	R:R:L229	R:R:T280	8.84	No	No	0	6	5
202	R:R:I232	R:R:Y236	4.84	No	Yes	1	8	9
203	R:R:M235	R:R:Y236	3.59	No	Yes	0	7	9
204	R:R:I239	R:R:Y236	2.42	No	Yes	0	8	9
205	R:R:L272	R:R:Y236	3.52	No	Yes	0	8	9
206	R:R:K242	R:R:L243	2.82	No	No	0	4	8
207	R:R:R260	R:R:R263	11.73	No	No	0	2	3
208	R:R:R260	R:R:R264	4.26	No	No	0	2	5
209	R:R:R265	R:R:S262	3.95	No	No	0	6	4
210	R:R:R264	R:R:R267	7.46	No	No	0	5	7
211	R:R:R267	R:R:V268	7.85	No	No	0	7	8
212	R:R:L272	R:R:M271	2.83	No	No	0	8	8
213	R:R:F332	R:R:M271	3.73	No	No	0	6	8
214	R:R:L277	R:R:V273	2.98	No	No	0	5	5
215	R:R:M274	R:R:V275	4.56	No	No	0	6	8
216	R:R:I328	R:R:M274	2.92	No	No	0	8	6
217	R:R:F278	R:R:I328	2.51	No	No	0	5	8
218	R:R:F279	R:R:W283	6.01	No	Yes	0	9	8
219	R:R:S282	R:R:W283	4.94	No	Yes	1	8	8
220	R:R:N321	R:R:S282	10.43	No	No	1	9	8
221	R:R:L286	R:R:W283	2.28	No	Yes	0	7	8
222	R:R:W283	R:R:W287	1.87	Yes	Yes	1	8	7
223	R:R:A318	R:R:W283	5.19	No	Yes	0	7	8
224	R:R:N321	R:R:W283	2.26	No	Yes	1	9	8
225	R:R:L284	R:R:P285	3.28	No	No	0	5	9
226	R:R:L286	R:R:L290	6.92	No	No	0	7	5
227	R:R:L289	R:R:V306	4.47	No	Yes	13	5	3
228	R:R:F311	R:R:L289	2.44	Yes	No	13	4	5
229	R:R:F311	R:R:L290	2.44	Yes	No	0	4	5
230	R:R:L292	R:R:L298	11.07	No	No	0	4	2
231	R:R:L298	R:R:Q302	9.32	No	No	0	2	2
232	R:R:P301	R:R:S299	3.56	No	No	0	4	3
233	R:R:Q302	R:R:S299	5.78	No	No	0	2	3
234	R:R:A300	R:R:P301	1.87	No	No	0	1	4
235	R:R:H304	R:R:V308	6.92	No	No	0	2	3
236	R:R:F311	R:R:V306	2.62	Yes	Yes	13	4	3
237	R:R:F311	R:R:H315	3.39	Yes	No	0	4	6
238	R:R:F313	R:R:L317	7.31	No	No	0	5	7
239	R:R:F319	R:R:H315	2.26	No	No	0	7	6
240	R:R:L317	R:R:W316	4.56	No	Yes	0	7	5
241	R:R:F320	R:R:W316	5.01	No	Yes	6	5	5
242	R:R:F320	R:R:S323	2.64	No	Yes	6	5	7
243	R:R:N325	R:R:Y329	6.98	No	No	12	9	9
244	R:R:F332	R:R:Y331	2.06	No	No	0	6	5
245	R:R:N333	R:R:N335	10.9	No	No	10	8	6
246	R:R:F336	R:R:N333	10.87	Yes	No	10	8	8
247	R:R:F336	R:R:N335	6.04	Yes	No	10	8	6
248	R:R:G108	R:R:L200	1.71	No	No	0	4	1
249	R:R:A169	R:R:S128	1.71	No	Yes	0	8	6
250	R:R:C174	R:R:V178	1.71	No	No	0	4	4
251	R:R:G296	R:R:L292	1.71	No	No	0	3	4
252	R:R:A86	R:R:V64	1.7	No	No	0	9	9
253	R:R:A310	R:R:V306	1.7	No	Yes	0	5	3
254	R:R:G296	R:R:Q297	1.64	No	No	0	3	2
255	R:R:V64	R:R:V68	1.6	No	No	0	9	6
256	R:R:V233	R:R:V234	1.6	No	No	0	4	3
257	R:R:V268	R:R:V269	1.6	No	No	0	8	7
258	R:R:T62	R:R:V59	1.59	No	No	0	4	5
259	R:R:T218	R:R:V215	1.59	No	No	0	4	4
260	L:L:P5	L:L:Q4	1.58	No	No	0	0	0
261	R:R:A43	R:R:L105	1.58	No	No	0	4	5
262	R:R:C57	R:R:N61	1.57	No	Yes	0	8	9
263	R:R:T76	R:R:T78	1.57	No	No	0	7	8
264	R:R:M118	R:R:S119	1.53	No	No	0	4	5
265	R:R:H147	R:R:P148	1.53	No	No	0	6	8
266	R:R:M235	R:R:V139	1.52	No	No	0	7	6
267	R:R:L226	R:R:S222	1.5	No	No	0	5	5
268	R:R:L52	R:R:V48	1.49	No	No	0	5	6
269	R:R:L83	R:R:V87	1.49	No	No	0	6	6
270	R:R:L90	R:R:V87	1.49	No	No	0	7	6
271	R:R:L91	R:R:V87	1.49	No	No	0	7	6
272	R:R:L101	R:R:V102	1.49	No	No	0	7	4
273	R:R:L231	R:R:V135	1.49	No	Yes	0	6	7
274	R:R:L168	R:R:V164	1.49	No	No	0	4	3
275	R:R:L229	R:R:V233	1.49	No	No	0	6	4
276	R:R:L272	R:R:V268	1.49	No	No	0	8	8
277	R:R:L298	R:R:V306	1.49	No	Yes	0	2	3
278	R:R:L303	R:R:V306	1.49	No	Yes	0	3	3
279	R:R:D89	R:R:S88	1.47	Yes	No	3	9	8
280	R:R:D89	R:R:S130	1.47	Yes	No	3	9	9
281	R:R:I145	R:R:I239	1.47	No	No	0	8	8
282	R:R:L281	R:R:T280	1.47	No	No	0	6	5
283	R:R:G296	R:R:Y295	1.45	No	No	0	3	4
284	R:R:M271	R:R:M274	1.44	No	No	0	8	6
285	R:R:I162	R:R:L159	1.43	No	No	0	8	3
286	R:R:L101	R:R:M97	1.41	No	Yes	0	7	7
287	R:R:E151	R:R:T154	1.41	No	No	0	6	7
288	R:R:P199	R:R:Y198	1.39	No	Yes	0	4	2
289	R:R:L69	R:R:L83	1.38	No	No	0	3	6
290	R:R:A261	R:R:R265	1.38	No	No	0	4	6
291	L:L:L2	L:L:Q4	1.33	No	No	0	0	0
292	L:L:F1	R:R:S33	1.32	No	No	0	0	5
293	R:R:F221	R:R:S222	1.32	Yes	No	0	6	5
294	R:R:F81	R:R:T133	1.3	Yes	No	0	8	8
295	R:R:F81	R:R:T161	1.3	Yes	No	0	8	6
296	R:R:R156	R:R:T154	1.29	No	No	0	5	7
297	R:R:S202	R:R:W204	1.24	No	Yes	0	4	3
298	R:R:F66	R:R:L63	1.22	No	No	0	4	6
299	R:R:E205	R:R:W204	1.09	Yes	Yes	0	4	3
300	R:R:F142	R:R:R238	1.07	Yes	No	0	8	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F3	8.048	5	7	0
2	L:L:R7	5.32	5	0	0
3	R:R:Y35	11.7675	4	2	4
4	R:R:H38	6.835	4	5	4
5	R:R:V42	5.1	4	5	4
6	R:R:F46	4.53	4	5	5
7	R:R:N61	5.0275	4	3	9
8	R:R:F81	3.828	5	0	8
9	R:R:L85	3.7575	4	12	9
10	R:R:D89	4.184	5	3	9
11	R:R:V92	4.2	4	0	7
12	R:R:M97	6.7825	4	0	7
13	R:R:W109	9.04	5	4	8
14	R:R:S128	2.936	5	1	6
15	R:R:W132	6.92	5	1	6
16	R:R:V135	3.4025	4	1	7
17	R:R:F142	7.575	4	0	8
18	R:R:M173	3.845	4	0	7
19	R:R:H188	4.4225	4	9	1
20	R:R:D192	9.31	4	2	5
21	R:R:R196	4.93	4	2	6
22	R:R:Y198	6.03833	6	2	2
23	R:R:C203	6.83	4	4	9
24	R:R:W204	2.79	4	0	3
25	R:R:E205	6.615	4	0	4
26	R:R:W207	8.73	4	0	5
27	R:R:L220	3.705	4	1	5
28	R:R:F221	4.97	4	1	6
29	R:R:H223	8.64	4	1	5
30	R:R:I224	4.8875	4	1	6
31	R:R:Y225	4.464	5	1	8
32	R:R:P228	3.9225	4	1	9
33	R:R:Y236	3.91833	6	1	9
34	R:R:W283	3.52	8	1	8
35	R:R:W287	5.215	6	1	7
36	R:R:V306	2.354	5	13	3
37	R:R:F311	2.7225	4	13	4
38	R:R:W316	5.132	5	6	5
39	R:R:S323	3.43	4	6	7
40	R:R:F336	5.53333	6	10	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:F3	R:R:Q37	15.2613	5.86	Yes	No	0	0	1
2	R:R:Q37	R:R:T107	37.0602	4.25	No	No	0	1	4
3	R:R:G108	R:R:T107	41.7812	1.82	No	No	0	4	4
4	R:R:G108	R:R:I106	53.8986	1.76	No	No	0	4	4
5	R:R:I106	R:R:P110	73.5061	3.39	No	No	0	4	3
6	R:R:F111	R:R:P110	74.8334	11.56	No	No	0	7	3
7	R:R:F111	R:R:W109	79.6794	17.04	No	Yes	0	7	8
8	L:L:Q6	R:R:W109	92.005	2.19	No	Yes	0	0	8
9	L:L:Q6	L:L:R7	76.6656	5.84	No	Yes	0	0	0
10	L:L:Q6	R:R:Q123	36.2742	3.84	No	No	0	0	7
11	L:L:R7	R:R:S176	35.3841	5.27	Yes	No	0	0	6
12	L:L:R7	R:R:L290	46.4241	2.43	Yes	No	0	0	5
13	R:R:S176	R:R:Y216	34.9313	8.9	No	No	0	6	6
14	R:R:L220	R:R:Y216	35.3061	5.86	Yes	No	0	5	6
15	R:R:L286	R:R:L290	48.4697	6.92	No	No	0	7	5
16	R:R:L286	R:R:W283	48.8549	2.28	No	Yes	0	7	8
17	R:R:V127	R:R:W283	41.5782	3.68	No	Yes	0	7	8
18	R:R:C96	R:R:Q123	36.7166	3.05	No	No	0	7	7
19	R:R:C96	R:R:V92	44.6492	3.42	No	Yes	0	7	7
20	R:R:S126	R:R:V92	51.7177	4.85	No	Yes	0	8	7
21	R:R:S126	R:R:V127	51.6032	3.23	No	No	0	8	7
22	R:R:W283	R:R:W287	11.9144	1.87	Yes	Yes	1	8	7
23	R:R:G108	R:R:L200	12.4558	1.71	No	No	0	4	1
24	R:R:I106	R:R:Y36	22.6941	3.63	No	No	0	4	4
25	R:R:Y35	R:R:Y36	21.0077	2.98	Yes	No	0	4	4
26	R:R:H38	R:R:Q37	20.7891	6.18	Yes	No	0	4	1
27	R:R:H38	R:R:V42	10.4934	8.3	Yes	Yes	5	4	4
28	R:R:S322	R:R:V92	87.2632	4.85	No	Yes	0	9	7
29	R:R:D89	R:R:S322	86.4408	5.89	Yes	No	0	9	9
30	R:R:D89	R:R:N61	54.8043	4.04	Yes	Yes	3	9	9
31	R:R:C57	R:R:N61	53.1803	1.57	No	Yes	0	8	9
32	R:R:C57	R:R:S323	52.0144	3.44	No	Yes	0	8	7
33	R:R:I53	R:R:S323	24.823	4.64	No	Yes	6	7	7
34	R:R:I53	R:R:W316	23.5322	3.52	No	Yes	6	7	5
35	R:R:W316	R:R:Y50	36.2638	8.68	Yes	No	0	5	7
36	R:R:M97	R:R:Y50	33.5363	3.59	Yes	No	0	7	7
37	R:R:F320	R:R:S323	24.823	2.64	No	Yes	6	5	7
38	R:R:F320	R:R:W316	23.5322	5.01	No	Yes	6	5	5
39	R:R:F54	R:R:M97	19.7429	8.71	No	Yes	0	6	7
40	R:R:F54	R:R:I94	14.1526	2.51	No	No	0	6	5
41	R:R:D89	R:R:P326	29.1016	8.05	Yes	No	3	9	9
42	R:R:P326	R:R:V64	32.3912	1.77	No	No	0	9	9
43	R:R:V64	R:R:V68	28.4249	1.6	No	No	0	9	6
44	R:R:F336	R:R:V68	25	3.93	Yes	No	0	8	6
45	R:R:F336	R:R:N79	13.6009	4.83	Yes	No	0	8	8
46	R:R:L220	R:R:M173	35.0094	4.24	Yes	Yes	0	5	7
47	R:R:M173	R:R:S128	31.8655	3.07	Yes	Yes	0	7	6
48	R:R:S128	R:R:W132	36.3315	2.47	Yes	Yes	1	6	6
49	R:R:V135	R:R:W132	38.0543	2.45	Yes	Yes	1	7	6
50	R:R:I232	R:R:V135	100	6.14	No	Yes	1	8	7
51	R:R:I232	R:R:Y236	96.6896	4.84	No	Yes	1	8	9
52	R:R:R141	R:R:Y236	33.6456	5.14	No	Yes	0	9	9
53	R:R:R141	R:R:Y329	31.8082	2.06	No	No	0	9	9
54	R:R:L85	R:R:Y329	27.9461	2.34	Yes	No	12	9	9
55	R:R:L85	R:R:T133	24.136	4.42	Yes	No	0	9	8
56	R:R:F81	R:R:T133	12.1539	1.3	Yes	No	0	8	8
57	R:R:F279	R:R:W283	64.4753	6.01	No	Yes	0	9	8
58	R:R:F279	R:R:V131	63.7258	2.62	No	No	0	9	8
59	R:R:P228	R:R:V131	67.6869	3.53	Yes	No	0	9	8
60	R:R:P228	R:R:V135	64.9282	3.53	Yes	Yes	1	9	7
61	R:R:N84	R:R:T133	10.3009	5.85	No	No	0	9	8
62	R:R:F95	R:R:I94	11.3419	5.02	No	No	0	6	5
63	R:R:C96	R:R:F319	10.2332	4.19	No	No	0	7	7
64	R:R:I224	R:R:W287	24.9167	2.35	Yes	Yes	1	6	7
65	R:R:H223	R:R:I224	10.4882	7.95	Yes	Yes	1	5	6
66	R:R:M235	R:R:Y236	21.7156	3.59	No	Yes	0	7	9
67	R:R:F142	R:R:M235	17.8638	11.2	Yes	No	0	8	7
68	R:R:I239	R:R:Y236	21.6219	2.42	No	Yes	0	8	9
69	R:R:F142	R:R:I239	17.8638	7.54	Yes	No	0	8	8
70	R:R:F142	R:R:V146	27.8316	10.49	Yes	No	0	8	6
71	R:R:H147	R:R:V146	15.964	5.54	No	No	0	6	6
72	L:L:R7	R:R:E205	24.3181	10.47	Yes	Yes	0	0	4
73	R:R:E205	R:R:W207	12.4922	3.27	Yes	Yes	0	4	5
74	R:R:Y198	R:R:Y35	10.5091	19.86	Yes	Yes	2	2	4
75	R:R:F311	R:R:L290	17.7962	2.44	Yes	No	0	4	5
76	R:R:F311	R:R:V306	18.806	2.62	Yes	Yes	13	4	3
77	R:R:L298	R:R:V306	14.6731	1.49	No	Yes	0	2	3
78	R:R:F221	R:R:W287	11.446	13.03	Yes	Yes	1	6	7
79	R:R:W283	R:R:Y225	14.4025	1.93	Yes	Yes	1	8	8
80	R:R:L229	R:R:Y225	11.7843	4.69	No	Yes	0	6	8
81	R:R:L272	R:R:Y236	27.8472	3.52	No	Yes	0	8	9
82	R:R:L272	R:R:V268	12.2371	1.49	No	No	0	8	8
83	R:R:L272	R:R:M271	14.1943	2.83	No	No	0	8	8
84	L:L:F8	R:R:V127	10.6288	3.93	No	No	0	0	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:F3	R:R:Q37	5.86	7	Yes	No	0	1	0	1
L:L:F3	R:R:D103	7.17	7	Yes	No	0	4	0	1
L:L:F3	R:R:N104	4.83	7	Yes	No	0	4	0	1
L:L:F3	R:R:T307	6.49	7	Yes	No	0	4	0	1
L:L:Q4	R:R:I293	5.49	0	No	No	0	4	0	1
L:L:P5	R:R:D103	4.83	7	No	No	0	4	0	1
L:L:Q6	R:R:W109	2.19	0	No	Yes	0	8	0	1
L:L:Q6	R:R:Q123	3.84	0	No	No	0	7	0	1
L:L:R7	R:R:S176	5.27	0	Yes	No	0	6	0	1
L:L:R7	R:R:E205	10.47	0	Yes	Yes	0	4	0	1
L:L:R7	R:R:T217	2.59	0	Yes	No	0	5	0	1
L:L:R7	R:R:L290	2.43	0	Yes	No	0	5	0	1
L:L:F8	R:R:V127	3.93	1	No	No	0	7	0	1
L:L:F8	R:R:L220	2.44	1	No	Yes	0	5	0	1
L:L:F8	R:R:W287	5.01	1	No	Yes	0	7	0	1
R:R:S33	R:R:T107	4.8	0	No	No	5	4	1	2
R:R:H38	R:R:Q37	6.18	5	Yes	No	4	1	2	1
R:R:Q37	R:R:T107	4.25	0	No	No	1	4	1	2
R:R:C96	R:R:Q123	3.05	0	No	No	7	7	2	1
R:R:N104	R:R:P312	6.52	0	No	No	4	3	1	2
R:R:F111	R:R:W109	17.04	0	No	Yes	7	8	2	1
R:R:C116	R:R:W109	11.75	4	No	Yes	9	8	2	1
R:R:S119	R:R:W109	2.47	0	No	Yes	5	8	2	1
R:R:C203	R:R:W109	11.75	4	Yes	Yes	9	8	2	1
R:R:C116	R:R:C203	7.28	4	No	Yes	9	9	2	2
R:R:G120	R:R:S119	1.86	0	No	No	5	5	2	2
R:R:G120	R:R:Q123	4.93	0	No	No	5	7	2	1
R:R:S126	R:R:V127	3.23	0	No	No	8	7	2	1
R:R:V127	R:R:W283	3.68	0	No	Yes	7	8	1	2
R:R:L220	R:R:M173	4.24	1	Yes	Yes	5	7	1	2
R:R:S176	R:R:Y216	8.9	0	No	No	6	6	1	2
R:R:E205	R:R:W207	3.27	0	Yes	Yes	4	5	1	2
R:R:E205	R:R:R213	11.63	0	Yes	No	4	4	1	2
R:R:D294	R:R:R213	8.34	0	No	No	5	4	2	2
R:R:L220	R:R:Y216	5.86	1	Yes	No	5	6	1	2
R:R:D294	R:R:T217	10.12	0	No	No	5	5	2	1
R:R:L220	R:R:W287	2.28	1	Yes	Yes	5	7	1	1
R:R:F221	R:R:Y225	3.09	1	Yes	Yes	6	8	2	2
R:R:F221	R:R:W287	13.03	1	Yes	Yes	6	7	2	1
R:R:I224	R:R:W287	2.35	1	Yes	Yes	6	7	2	1
R:R:W283	R:R:Y225	1.93	1	Yes	Yes	8	8	2	2
R:R:W287	R:R:Y225	6.75	1	Yes	Yes	7	8	1	2
R:R:L286	R:R:W283	2.28	0	No	Yes	7	8	2	2
R:R:W283	R:R:W287	1.87	1	Yes	Yes	8	7	2	1
R:R:L286	R:R:L290	6.92	0	No	No	7	5	2	1
R:R:F311	R:R:L290	2.44	13	Yes	No	4	5	2	1
L:L:F1	R:R:S33	1.32	0	No	No	0	5	0	1
R:R:E205	R:R:W204	1.09	0	Yes	Yes	4	3	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9VIF_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.76
Number of Linked Nodes	270
Number of Links	300
Number of Hubs	40
Number of Links mediated by Hubs	152
Number of Communities	13
Number of Nodes involved in Communities	61
Number of Links involved in Communities	76

Path Summary
Number Of Nodes in MetaPath	85
Number Of Links MetaPath	84
Number of Shortest Paths	47826
Length Of Smallest Path	3
Average Path Length	15.319
Length of Longest Path	32
Minimum Path Strength	1.165
Average Path Strength	4.90557
Maximum Path Strength	16.28
Minimum Path Correlation	0.7
Average Path Correlation	0.933307
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	51.7171
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.1842
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to endogenous stimulus • response to chemical • cellular response to hormone stimulus • membrane-bounded organelle • cell projection • cellular anatomical structure • organelle • cilium • plasma membrane bounded cell projection • cell periphery • plasma membrane • membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9GZQ6
Sequence	>9VIF_nogp_Chain_R N L T F S S Y Y Q H T S P V A A M F I V A Y A L I F L L C M V G N T L V C F I V L K N R H M H T V T N M F I L N L A V S D L L V G I F C M P T T L V D N L I T G W P F D N A T C K M S G L V Q G M S V S A S V T L V A I A V E R F R C I V H P F R E K L T L R K A L V T I A V I W A L A L L I M C P S A V T L T V T R E E H H F M V D A R N R S Y P L Y S C W E A W P E K G M R R V Y T T V L F S H I Y L A P L A L I V V M Y A R I A R K L C Q A P R A S R R R A R V V H M L V M V A L F F T L S W L P L W A L L L L I D Y G Q L S A P Q L H L V T V Y A F P F A H W L A F F N S S A N P I I Y G Y F N E N F R R W Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9M0R	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-VF	-	Gi1/β1/γ2	2.47	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9M0R (No Gprot)	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-VF	-		2.47	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9M2F	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-FF	-	Gi1/β1/γ2	2.93	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9M2F (No Gprot)	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-FF	-		2.93	2025-07-23	doi.org/10.1016/j.celrep.2025.116160
	9VI9	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	RFRP-3	-	Gi1/β1/γ2	3.02	2025-12-03	10.1093/procel/pwaf090
	9VI9 (No Gprot)	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	RFRP-3	-		3.02	2025-12-03	10.1093/procel/pwaf090
	9VIF	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-VF	-	Gi1/β1/γ2	3.19	2025-12-03	10.1093/procel/pwaf090
	9VIF (No Gprot)	A	Peptide	Neuropeptide FF	NPFF1	Homo sapiens	Neuropeptide-VF	-		3.19	2025-12-03	10.1093/procel/pwaf090

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