psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E110	R:R:R24	12.79	Yes	No	5	7	6
2	R:R:R24	R:R:W192	8	No	No	5	6	4
3	R:R:H25	R:R:V36	5.54	No	No	0	6	7
4	R:R:E191	R:R:H25	9.85	Yes	No	0	3	6
5	R:R:S26	R:R:Y34	3.82	No	No	0	8	3
6	R:R:E191	R:R:S26	4.31	Yes	No	0	3	8
7	R:R:C27	R:R:P28	3.77	Yes	No	4	6	7
8	R:R:C27	R:R:D38	4.67	Yes	No	0	6	1
9	R:R:C27	R:R:C40	5.46	Yes	No	4	6	4
10	R:R:C27	R:R:E43	4.56	Yes	Yes	4	6	5
11	R:R:E43	R:R:P28	11	Yes	No	4	5	7
12	R:R:F300	R:R:P28	10.11	Yes	No	4	4	7
13	R:R:E43	R:R:L29	6.63	Yes	Yes	4	5	5
14	R:R:L29	R:R:T297	5.9	Yes	No	0	5	1
15	R:R:F300	R:R:L29	4.87	Yes	Yes	4	4	5
16	R:R:C40	R:R:E43	4.56	No	Yes	4	4	5
17	R:R:E43	R:R:F42	7	Yes	No	0	5	4
18	R:R:F42	R:R:V46	7.87	No	No	0	4	4
19	R:R:E43	R:R:F300	4.66	Yes	Yes	4	5	4
20	R:R:L101	R:R:T44	11.79	No	No	0	4	6
21	R:R:I47	R:R:T98	4.56	No	No	0	5	6
22	R:R:F300	R:R:I47	5.02	Yes	No	4	4	5
23	R:R:I47	R:R:W304	16.44	No	Yes	4	5	4
24	R:R:F311	R:R:L53	6.09	Yes	No	0	6	5
25	R:R:I54	R:R:V90	4.61	No	Yes	6	7	8
26	R:R:I54	R:R:S310	9.29	No	Yes	6	7	9
27	R:R:G57	R:R:P314	4.06	No	No	0	8	9
28	R:R:D87	R:R:N58	6.73	No	No	0	9	9
29	R:R:N58	R:R:P314	9.77	No	No	0	9	9
30	R:R:F63	R:R:L59	10.96	No	No	0	4	5
31	R:R:V61	R:R:Y317	5.05	No	Yes	0	9	9
32	R:R:I62	R:R:Y85	16.92	No	No	0	8	6
33	R:R:I62	R:R:L88	4.28	No	No	0	8	6
34	R:R:F324	R:R:V64	9.18	Yes	No	0	8	8
35	R:R:F65	R:R:S77	3.96	No	No	0	7	8
36	R:R:F65	R:R:I80	3.77	No	No	0	7	8
37	R:R:F65	R:R:Q81	21.08	No	No	0	7	6
38	R:R:L71	R:R:Y74	14.07	No	No	0	8	4
39	R:R:H72	R:R:H73	9.55	No	No	1	8	7
40	R:R:H72	R:R:Y263	5.44	No	Yes	1	8	7
41	R:R:H73	R:R:R139	5.64	No	Yes	1	7	9
42	R:R:H73	R:R:Y263	21.78	No	Yes	1	7	7
43	R:R:D138	R:R:T75	10.12	Yes	Yes	1	9	6
44	R:R:T75	R:R:Y149	4.99	Yes	Yes	1	6	8
45	R:R:T75	R:R:V153	4.76	Yes	Yes	1	6	7
46	R:R:L158	R:R:T75	4.42	No	Yes	0	7	6
47	R:R:D138	R:R:T76	5.78	Yes	Yes	1	9	8
48	R:R:R139	R:R:T76	5.17	Yes	Yes	1	9	8
49	R:R:T76	R:R:Y263	8.74	Yes	Yes	1	8	7
50	R:R:L267	R:R:T76	4.42	No	Yes	1	8	8
51	R:R:L158	R:R:Y78	5.86	No	No	0	7	4
52	R:R:C134	R:R:F79	11.17	No	No	0	6	8
53	R:R:F79	R:R:I135	3.77	No	No	0	8	9
54	R:R:I80	R:R:Y317	7.25	No	Yes	0	8	9
55	R:R:Q81	R:R:Y85	5.64	No	No	0	6	6
56	R:R:T82	R:R:W166	4.85	No	No	0	9	9
57	R:R:M83	R:R:S128	7.67	Yes	No	0	9	9
58	R:R:C131	R:R:M83	4.86	No	Yes	0	8	9
59	R:R:L132	R:R:M83	7.07	No	Yes	0	8	9
60	R:R:M83	R:R:N313	4.21	Yes	Yes	0	9	9
61	R:R:F89	R:R:Y85	4.13	No	No	0	7	6
62	R:R:D87	R:R:S310	8.83	No	Yes	0	9	9
63	R:R:D87	R:R:N313	4.04	No	Yes	0	9	9
64	R:R:I121	R:R:V90	6.14	Yes	Yes	0	6	8
65	R:R:L124	R:R:V90	5.96	No	Yes	0	7	8
66	R:R:S310	R:R:V90	8.08	Yes	Yes	6	9	8
67	R:R:I120	R:R:S93	6.19	No	No	0	5	4
68	R:R:I121	R:R:S93	4.64	Yes	No	0	6	4
69	R:R:C94	R:R:P97	3.77	No	Yes	0	7	4
70	R:R:F117	R:R:P97	11.56	No	Yes	0	5	4
71	R:R:F190	R:R:P97	8.67	Yes	Yes	0	3	4
72	R:R:F190	R:R:S100	9.25	Yes	No	0	3	4
73	R:R:I189	R:R:L101	4.28	No	No	0	4	4
74	R:R:H109	R:R:V108	4.15	No	No	0	6	1
75	R:R:H109	R:R:L112	20.57	No	No	0	6	1
76	R:R:H109	R:R:T113	8.21	No	No	0	6	5
77	R:R:E110	R:R:F190	7	Yes	Yes	0	7	3
78	R:R:E110	R:R:E191	3.81	Yes	Yes	0	7	3
79	R:R:E110	R:R:W192	31.62	Yes	No	5	7	4
80	R:R:S111	R:R:W192	12.36	No	No	0	3	4
81	R:R:S111	R:R:W197	11.12	No	Yes	0	3	5
82	R:R:C114	R:R:F190	8.38	No	Yes	0	9	3
83	R:R:C114	R:R:C193	7.28	No	No	0	9	9
84	R:R:F177	R:R:Q115	11.71	Yes	No	0	5	6
85	R:R:Q115	R:R:W197	4.38	No	Yes	0	6	5
86	R:R:F117	R:R:I121	5.02	No	Yes	0	5	6
87	R:R:V123	R:R:Y119	6.31	No	Yes	0	5	6
88	R:R:S176	R:R:Y119	3.82	No	Yes	8	5	6
89	R:R:F177	R:R:Y119	6.19	Yes	Yes	8	5	6
90	R:R:H186	R:R:I121	9.28	No	Yes	0	2	6
91	R:R:F173	R:R:S122	7.93	Yes	No	0	6	5
92	R:R:H186	R:R:S122	5.58	No	No	0	2	5
93	R:R:F173	R:R:V123	3.93	Yes	No	0	6	5
94	R:R:K125	R:R:Q278	10.85	No	No	0	6	8
95	R:R:K125	R:R:S310	4.59	No	Yes	0	6	9
96	R:R:S126	R:R:S169	6.52	No	No	0	6	8
97	R:R:L211	R:R:S126	6.01	Yes	No	0	7	6
98	R:R:I165	R:R:V127	4.61	No	Yes	0	6	6
99	R:R:V127	R:R:W166	13.48	Yes	No	0	6	9
100	R:R:S169	R:R:V127	4.85	No	Yes	0	8	6
101	R:R:L211	R:R:M129	4.24	Yes	No	0	7	7
102	R:R:F274	R:R:M129	4.98	Yes	No	0	9	7
103	R:R:M129	R:R:Y275	4.79	No	No	0	7	5
104	R:R:I165	R:R:W130	5.87	No	Yes	0	6	5
105	R:R:W130	R:R:Y168	6.75	Yes	No	0	5	4
106	R:R:L211	R:R:W130	4.56	Yes	Yes	0	7	5
107	R:R:P214	R:R:W130	5.4	No	Yes	0	9	5
108	R:R:A215	R:R:W130	7.78	No	Yes	0	5	5
109	R:R:L132	R:R:T271	11.79	No	No	0	8	8
110	R:R:F274	R:R:L132	7.31	Yes	No	0	9	8
111	R:R:S136	R:R:T222	9.59	No	No	2	8	7
112	R:R:S136	R:R:Y223	6.36	No	Yes	2	8	9
113	R:R:D138	R:R:R139	8.34	Yes	Yes	1	9	9
114	R:R:D138	R:R:Y149	10.34	Yes	Yes	1	9	8
115	R:R:D138	R:R:V153	4.38	Yes	Yes	1	9	7
116	R:R:A142	R:R:R139	5.53	No	Yes	0	8	9
117	R:R:T144	R:R:Y140	9.99	No	Yes	2	6	8
118	R:R:K145	R:R:Y140	4.78	Yes	Yes	2	6	8
119	R:R:F221	R:R:Y140	6.19	No	Yes	2	4	8
120	R:R:H225	R:R:Y140	5.44	No	Yes	2	5	8
121	R:R:A142	R:R:Y149	4	No	Yes	0	8	8
122	R:R:I143	R:R:I229	4.42	No	No	0	9	6
123	R:R:K145	R:R:T144	13.51	Yes	No	2	6	6
124	R:R:K145	R:R:S148	6.12	Yes	No	0	6	5
125	R:R:N150	R:R:Y149	5.81	No	Yes	0	4	8
126	R:R:V153	R:R:Y149	13.88	Yes	Yes	1	7	8
127	R:R:N150	R:R:Q151	3.96	No	No	0	4	4
128	R:R:P155	R:R:T154	5.25	No	No	0	3	8
129	R:R:R157	R:R:T154	5.17	No	No	0	5	8
130	R:R:I172	R:R:Y168	8.46	Yes	No	9	5	4
131	R:R:L210	R:R:Y168	5.86	No	No	9	5	4
132	R:R:F173	R:R:I172	5.02	Yes	Yes	0	6	5
133	R:R:I172	R:R:L210	4.28	Yes	No	9	5	5
134	R:R:I172	R:R:L211	5.71	Yes	Yes	0	5	7
135	R:R:F173	R:R:P183	4.33	Yes	No	0	6	4
136	R:R:F173	R:R:I207	5.02	Yes	No	0	6	6
137	R:R:F178	R:R:L174	4.87	No	No	0	5	4
138	R:R:P175	R:R:W180	5.4	No	No	0	6	6
139	R:R:F203	R:R:P175	11.56	Yes	No	0	5	6
140	R:R:F177	R:R:S176	3.96	Yes	No	8	5	5
141	R:R:P183	R:R:S176	7.13	No	No	0	4	5
142	R:R:K182	R:R:W197	33.65	No	Yes	0	3	5
143	R:R:F203	R:R:P183	5.78	Yes	No	0	5	4
144	R:R:F285	R:R:G184	4.52	Yes	No	0	5	2
145	R:R:D188	R:R:Y185	10.34	No	Yes	3	4	7
146	R:R:Y185	R:R:Y281	3.97	Yes	No	0	7	6
147	R:R:Y185	R:R:Y284	17.87	Yes	Yes	3	7	4
148	R:R:F285	R:R:Y185	12.38	Yes	Yes	3	5	7
149	R:R:E288	R:R:Y185	15.71	Yes	Yes	3	3	7
150	R:R:S299	R:R:Y185	5.09	No	Yes	3	4	7
151	R:R:H186	R:R:Y281	17.42	No	No	0	2	6
152	R:R:C193	R:R:G187	3.92	No	No	0	9	4
153	R:R:D188	R:R:S299	5.89	No	No	3	4	4
154	R:R:I189	R:R:W304	4.7	No	Yes	0	4	4
155	R:R:C193	R:R:W197	11.75	No	Yes	0	9	5
156	R:R:S196	R:R:W197	11.12	No	Yes	0	3	5
157	R:R:L198	R:R:R291	13.36	No	No	0	5	1
158	R:R:E288	R:R:T199	7.06	Yes	No	3	3	3
159	R:R:S289	R:R:T199	7.99	No	No	3	4	3
160	R:R:R291	R:R:T199	6.47	No	No	3	1	3
161	R:R:F203	R:R:F206	4.29	Yes	No	0	5	5
162	R:R:F285	R:R:T204	12.97	Yes	No	3	5	5
163	R:R:S289	R:R:T204	9.59	No	No	3	4	5
164	R:R:F206	R:R:L210	6.09	No	No	0	5	5
165	R:R:I207	R:R:Y212	4.84	No	Yes	0	6	5
166	R:R:F285	R:R:I207	3.77	Yes	No	0	5	6
167	R:R:V208	R:R:Y212	3.79	No	Yes	0	4	5
168	R:R:L211	R:R:Y212	8.21	Yes	Yes	0	7	5
169	R:R:I282	R:R:Y212	4.84	No	Yes	0	6	5
170	R:R:A216	R:R:Y275	4	No	No	0	4	5
171	R:R:V219	R:R:Y275	3.79	No	No	0	5	5
172	R:R:F221	R:R:H225	12.44	No	No	2	4	5
173	R:R:T222	R:R:Y223	4.99	No	Yes	2	7	9
174	R:R:I226	R:R:Y223	7.25	No	Yes	0	9	9
175	R:R:F227	R:R:Y223	5.16	No	Yes	2	7	9
176	R:R:F268	R:R:Y223	12.38	No	Yes	2	5	9
177	R:R:T271	R:R:Y223	4.99	No	Yes	0	8	9
178	R:R:F224	R:R:H225	4.53	No	No	0	4	5
179	R:R:F224	R:R:K228	4.96	No	No	0	4	4
180	R:R:I226	R:R:L264	4.28	No	No	0	9	7
181	R:R:F227	R:R:F268	9.65	No	No	2	7	5
182	R:R:Q232	R:R:R231	4.67	No	No	0	4	5
183	R:R:L267	R:R:Y263	5.86	No	Yes	1	8	7
184	R:R:F268	R:R:S272	3.96	No	No	0	5	5
185	R:R:I270	R:R:N313	7.08	Yes	Yes	7	8	9
186	R:R:I270	R:R:I316	4.42	Yes	No	0	8	8
187	R:R:I270	R:R:Y317	6.04	Yes	Yes	7	8	9
188	R:R:F274	R:R:Q278	9.37	Yes	No	0	9	8
189	R:R:F274	R:R:N309	12.08	Yes	No	0	9	9
190	R:R:L277	R:R:L305	4.15	No	No	0	8	7
191	R:R:L277	R:R:N309	9.61	No	No	0	8	9
192	R:R:A306	R:R:Q278	6.06	No	No	0	7	8
193	R:R:L305	R:R:P280	4.93	No	No	0	7	9
194	R:R:T303	R:R:Y281	4.99	No	No	0	5	6
195	R:R:E288	R:R:Y284	6.73	Yes	Yes	3	3	4
196	R:R:L298	R:R:Y284	7.03	No	Yes	0	4	4
197	R:R:S299	R:R:Y284	7.63	No	Yes	3	4	4
198	R:R:T302	R:R:Y284	6.24	No	Yes	0	5	4
199	R:R:F285	R:R:S289	7.93	Yes	No	3	5	4
200	R:R:L287	R:R:V292	8.94	No	No	0	4	3
201	R:R:E288	R:R:R291	11.63	Yes	No	3	3	1
202	R:R:D294	R:R:E288	6.5	No	Yes	0	3	3
203	R:R:S290	R:R:V292	4.85	No	No	0	4	3
204	R:R:N295	R:R:P296	4.89	No	No	0	3	2
205	R:R:N295	R:R:T297	4.39	No	No	0	3	1
206	R:R:L298	R:R:N295	6.87	No	No	0	4	3
207	R:R:F300	R:R:W304	16.04	Yes	Yes	4	4	4
208	R:R:T303	R:R:W304	7.28	No	Yes	0	5	4
209	R:R:I307	R:R:W304	16.44	No	Yes	0	6	4
210	R:R:F311	R:R:S308	6.61	Yes	No	0	6	6
211	R:R:C312	R:R:F311	4.19	No	Yes	0	5	6
212	R:R:N313	R:R:Y317	6.98	Yes	Yes	7	9	9
213	R:R:F324	R:R:Y317	5.16	Yes	Yes	0	8	9
214	R:R:F324	R:R:L328	7.31	Yes	No	0	8	7
215	R:R:R325	R:R:R329	6.4	No	No	0	9	5
216	R:R:E333	R:R:R330	9.3	No	No	0	4	5
217	R:R:L331	R:R:M335	4.24	No	No	0	6	4
218	R:R:E333	R:R:T337	4.23	No	No	0	4	4
219	R:R:I316	R:R:R269	3.76	No	No	0	8	7
220	R:R:T222	R:R:Y140	3.75	No	Yes	2	7	8
221	R:R:G91	R:R:V90	3.68	No	Yes	0	6	8
222	R:R:F52	R:R:L53	3.65	No	No	0	5	5
223	R:R:F79	R:R:L158	3.65	No	No	0	8	7
224	R:R:I135	R:R:Y223	3.63	No	Yes	0	9	9
225	R:R:D321	R:R:F324	3.58	No	Yes	0	8	8
226	R:R:G91	R:R:I55	3.53	No	No	0	6	6
227	R:R:P97	R:R:V96	3.53	Yes	No	0	4	7
228	R:R:A84	R:R:V61	3.39	No	No	0	9	9
229	R:R:A86	R:R:V127	3.39	No	Yes	0	8	6
230	R:R:A133	R:R:V218	3.39	No	No	0	7	8
231	R:R:C94	R:R:T51	3.38	No	No	0	7	6
232	R:R:C161	R:R:I165	3.27	No	No	0	6	6
233	R:R:S35	R:R:V37	3.23	No	No	0	5	2
234	R:R:S320	R:R:V266	3.23	No	No	0	7	8
235	R:R:S196	R:R:T195	3.2	No	No	0	3	4
236	R:R:T98	R:R:V48	3.17	No	No	0	6	4
237	R:R:I41	R:R:V39	3.07	No	No	0	6	4
238	R:R:I55	R:R:V92	3.07	No	No	0	6	4
239	R:R:I270	R:R:V266	3.07	Yes	No	0	8	8
240	R:R:M276	R:R:S272	3.07	No	No	0	4	5
241	R:R:I316	R:R:V273	3.07	No	No	0	8	7
242	R:R:I162	R:R:T82	3.04	No	No	0	8	9
243	R:R:L141	R:R:V137	2.98	No	No	0	5	6
244	R:R:L141	R:R:V153	2.98	No	Yes	0	5	7
245	R:R:L102	R:R:T44	2.95	No	No	0	4	6
246	R:R:L328	R:R:T60	2.95	No	No	0	7	6
247	R:R:D38	R:R:S35	2.94	No	No	0	1	5
248	R:R:D321	R:R:T323	2.89	No	No	0	8	7
249	R:R:I55	R:R:L59	2.85	No	No	0	6	5
250	R:R:I160	R:R:L164	2.85	No	No	0	3	3
251	R:R:I282	R:R:L279	2.85	No	No	0	6	6
252	R:R:E333	R:R:T334	2.82	No	No	0	4	5
253	R:R:H33	R:R:S35	2.79	No	No	0	4	5
254	R:R:L49	R:R:L50	2.77	No	No	0	4	6
255	R:R:A56	R:R:F52	2.77	No	No	0	4	5
256	R:R:L286	R:R:L287	2.77	No	No	0	5	4
257	R:R:A318	R:R:F324	2.77	No	Yes	0	7	8
258	R:R:C170	R:R:Y119	2.69	No	Yes	0	4	6
259	R:R:H66	R:R:I62	2.65	No	No	0	3	8
260	R:R:F203	R:R:S200	2.64	Yes	No	0	5	3
261	R:R:R262	R:R:S320	2.64	No	No	0	8	7
262	R:R:R325	R:R:S322	2.64	No	No	0	9	5
263	R:R:F177	R:R:V116	2.62	Yes	No	0	5	4
264	R:R:H233	R:R:K235	2.62	No	No	0	7	6
265	R:R:F190	R:R:T113	2.59	Yes	No	0	3	5
266	R:R:A133	R:R:W130	2.59	No	Yes	0	7	5
267	R:R:F311	R:R:I54	2.51	Yes	No	0	6	7
268	R:R:I163	R:R:R159	2.51	No	No	0	3	3
269	R:R:M265	R:R:R262	2.48	No	No	0	7	8
270	R:R:F31	R:R:L29	2.44	No	Yes	0	5	5
271	R:R:F311	R:R:L50	2.44	Yes	No	0	6	6
272	R:R:F63	R:R:L331	2.44	No	No	0	4	6
273	R:R:L326	R:R:R330	2.43	No	No	0	4	5
274	R:R:L70	R:R:Y74	2.34	No	No	0	5	4
275	R:R:L174	R:R:Y119	2.34	No	Yes	0	4	6
276	R:R:R262	R:R:R325	2.13	No	No	0	8	9
277	R:R:G118	R:R:G187	2.11	No	No	0	5	4
278	R:R:C27	R:R:G30	1.96	Yes	No	0	6	5
279	R:R:A68	R:R:P69	1.87	No	No	0	6	6
280	R:R:A213	R:R:P214	1.87	No	No	0	5	9
281	R:R:G107	R:R:S105	1.86	No	No	0	7	4
282	R:R:G181	R:R:S200	1.86	No	No	0	6	3
283	R:R:G327	R:R:V64	1.84	No	No	0	7	8
284	R:R:G107	R:R:V108	1.84	No	No	0	7	1
285	R:R:G205	R:R:V208	1.84	No	No	0	4	4
286	R:R:C156	R:R:T154	1.69	No	No	0	4	8
287	R:R:K145	R:R:P146	1.67	Yes	No	0	6	8
288	R:R:L70	R:R:P69	1.64	No	No	0	5	6
289	R:R:C156	R:R:I160	1.64	No	No	0	4	3
290	R:R:C230	R:R:L264	1.59	No	No	0	8	7
291	R:R:A194	R:R:E191	1.51	No	Yes	0	4	3
292	R:R:L71	R:R:S77	1.5	No	No	0	8	8
293	R:R:L95	R:R:V92	1.49	No	No	0	7	4
294	R:R:L152	R:R:V153	1.49	No	Yes	0	4	7
295	R:R:I163	R:R:I167	1.47	No	No	0	3	4
296	R:R:I282	R:R:I283	1.47	No	No	0	6	5
297	R:R:G32	R:R:Y34	1.45	No	No	0	4	3
298	R:R:I167	R:R:L171	1.43	No	No	0	4	4
299	R:R:Q232	R:R:T234	1.42	No	No	0	4	5
300	R:R:H103	R:R:V39	1.38	No	No	0	4	4
301	R:R:L171	R:R:L174	1.38	No	No	0	4	4
302	R:R:L293	R:R:L298	1.38	No	No	0	1	4
303	R:R:H103	R:R:T106	1.37	No	No	0	4	4
304	R:R:S105	R:R:Y104	1.27	No	No	0	4	4
305	R:R:M265	R:R:R261	1.24	No	No	0	7	5
306	R:R:F300	R:R:L301	1.22	Yes	No	0	4	3
307	R:R:L152	R:R:R157	1.21	No	No	0	4	5
308	R:R:R329	R:R:R330	1.07	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:C27	4.084	5	4	6
2	R:R:L29	4.96	4	4	5
3	R:R:E43	6.40167	6	4	5
4	R:R:T75	6.0725	4	1	6
5	R:R:T76	6.0275	4	1	8
6	R:R:M83	5.9525	4	0	9
7	R:R:V90	5.694	5	6	8
8	R:R:P97	6.8825	4	0	4
9	R:R:E110	13.805	4	5	7
10	R:R:Y119	4.27	5	8	6
11	R:R:I121	6.27	4	0	6
12	R:R:V127	6.5825	4	0	6
13	R:R:W130	5.49167	6	0	5
14	R:R:D138	7.792	5	1	9
15	R:R:R139	6.17	4	1	9
16	R:R:Y140	6.03	5	2	8
17	R:R:K145	6.52	4	2	6
18	R:R:Y149	7.804	5	1	8
19	R:R:V153	5.498	5	1	7
20	R:R:I172	5.8675	4	9	5
21	R:R:F173	5.246	5	0	6
22	R:R:F177	6.12	4	8	5
23	R:R:Y185	10.8933	6	3	7
24	R:R:F190	7.178	5	0	3
25	R:R:E191	4.87	4	0	3
26	R:R:W197	14.404	5	0	5
27	R:R:F203	6.0675	4	0	5
28	R:R:L211	5.746	5	0	7
29	R:R:Y212	5.42	4	0	5
30	R:R:Y223	6.39429	7	2	9
31	R:R:Y263	10.455	4	1	7
32	R:R:I270	5.1525	4	7	8
33	R:R:F274	8.435	4	0	9
34	R:R:Y284	9.1	5	3	4
35	R:R:F285	8.314	5	3	5
36	R:R:E288	9.526	5	3	3
37	R:R:F300	6.98667	6	4	4
38	R:R:W304	12.18	5	4	4
39	R:R:S310	7.6975	4	6	9
40	R:R:F311	4.368	5	0	6
41	R:R:N313	5.5775	4	7	9
42	R:R:Y317	6.096	5	7	9
43	R:R:F324	5.6	5	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E110	R:R:E191	12.2592	3.81	Yes	Yes	0	7	3
2	R:R:C27	R:R:P28	14.3754	3.77	Yes	No	4	6	7
3	R:R:F300	R:R:P28	16.7872	10.11	Yes	No	4	4	7
4	R:R:F300	R:R:W304	50.3562	16.04	Yes	Yes	4	4	4
5	R:R:T303	R:R:W304	70.5156	7.28	No	Yes	0	5	4
6	R:R:T303	R:R:Y281	72.7004	4.99	No	No	0	5	6
7	R:R:H186	R:R:Y281	68.5313	17.42	No	No	0	2	6
8	R:R:H186	R:R:I121	67.7344	9.28	No	Yes	0	2	6
9	R:R:F117	R:R:I121	45.2267	5.02	No	Yes	0	5	6
10	R:R:F117	R:R:P97	43.7859	11.56	No	Yes	0	5	4
11	R:R:F190	R:R:P97	38.2923	8.67	Yes	Yes	0	3	4
12	R:R:E110	R:R:F190	16.4705	7	Yes	Yes	0	7	3
13	R:R:C27	R:R:E43	14.9084	4.56	Yes	Yes	4	6	5
14	R:R:E43	R:R:F300	23.901	4.66	Yes	Yes	4	5	4
15	R:R:C27	R:R:D38	19.5841	4.67	Yes	No	0	6	1
16	R:R:Y185	R:R:Y281	27.1518	3.97	Yes	No	0	7	6
17	R:R:Y185	R:R:Y284	10.1641	17.87	Yes	Yes	3	7	4
18	R:R:I121	R:R:V90	81.3394	6.14	Yes	Yes	0	6	8
19	R:R:F311	R:R:I54	13.7158	2.51	Yes	No	0	6	7
20	R:R:S310	R:R:V90	76.4262	8.08	Yes	Yes	6	9	8
21	R:R:D87	R:R:S310	58.1139	8.83	No	Yes	0	9	9
22	R:R:G91	R:R:V90	14.7132	3.68	No	Yes	0	6	8
23	R:R:G91	R:R:I55	12.8872	3.53	No	No	0	6	6
24	R:R:D87	R:R:N313	57.1006	4.04	No	Yes	0	9	9
25	R:R:N313	R:R:Y317	35.5586	6.98	Yes	Yes	7	9	9
26	R:R:I80	R:R:Y317	21.9537	7.25	No	Yes	0	8	9
27	R:R:F65	R:R:I80	20.4391	3.77	No	No	0	7	8
28	R:R:F324	R:R:Y317	12.8292	5.16	Yes	Yes	0	8	9
29	R:R:M83	R:R:N313	54.1612	4.21	Yes	Yes	0	9	9
30	R:R:L132	R:R:M83	54.1453	7.07	No	Yes	0	8	9
31	R:R:L132	R:R:T271	100	11.79	No	No	0	8	8
32	R:R:T271	R:R:Y223	98.1371	4.99	No	Yes	0	8	9
33	R:R:I135	R:R:Y223	61.2011	3.63	No	Yes	0	9	9
34	R:R:F79	R:R:I135	59.1588	3.77	No	No	0	8	9
35	R:R:F79	R:R:L158	55.0055	3.65	No	No	0	8	7
36	R:R:L158	R:R:T75	50.9209	4.42	No	Yes	0	7	6
37	R:R:D138	R:R:T75	17.6474	10.12	Yes	Yes	1	9	6
38	R:R:K125	R:R:S310	30.7668	4.59	No	Yes	0	6	9
39	R:R:K125	R:R:Q278	30.4713	10.85	No	No	0	6	8
40	R:R:F274	R:R:Q278	30.9146	9.37	Yes	No	0	9	8
41	R:R:F274	R:R:L132	87.1708	7.31	Yes	No	0	9	8
42	R:R:T75	R:R:V153	22.3178	4.76	Yes	Yes	1	6	7
43	R:R:H186	R:R:S122	42.7094	5.58	No	No	0	2	5
44	R:R:F173	R:R:S122	42.7305	7.93	Yes	No	0	6	5
45	R:R:F173	R:R:I172	51.9975	5.02	Yes	Yes	0	6	5
46	R:R:I165	R:R:W130	16.1486	5.87	No	Yes	0	6	5
47	R:R:I165	R:R:V127	11.6101	4.61	No	Yes	0	6	6
48	R:R:V127	R:R:W166	11.9004	13.48	Yes	No	0	6	9
49	R:R:I172	R:R:L211	47.1423	5.71	Yes	Yes	0	5	7
50	R:R:L211	R:R:W130	21.9959	4.56	Yes	Yes	0	7	5
51	R:R:L211	R:R:S126	11.6682	6.01	Yes	No	0	7	6
52	R:R:F190	R:R:T113	12.5917	2.59	Yes	No	0	3	5
53	R:R:H109	R:R:T113	10.8238	8.21	No	No	0	6	5
54	R:R:Q115	R:R:W197	16.898	4.38	No	Yes	0	6	5
55	R:R:F177	R:R:Q115	19.3889	11.71	Yes	No	0	5	6
56	R:R:F177	R:R:Y119	12.6709	6.19	Yes	Yes	8	5	6
57	R:R:V123	R:R:Y119	23.1886	6.31	No	Yes	0	5	6
58	R:R:F177	R:R:S176	12.4334	3.96	Yes	No	8	5	5
59	R:R:F274	R:R:M129	71.8824	4.98	Yes	No	0	9	7
60	R:R:L211	R:R:M129	72.7479	4.24	Yes	No	0	7	7
61	R:R:T222	R:R:Y223	22.8983	4.99	No	Yes	2	7	9
62	R:R:T222	R:R:Y140	20.7029	3.75	No	Yes	2	7	8
63	R:R:L152	R:R:V153	16.175	1.49	No	Yes	0	4	7
64	R:R:L152	R:R:R157	13.8952	1.21	No	No	0	4	5
65	R:R:R157	R:R:T154	11.6048	5.17	No	No	0	5	8
66	R:R:P183	R:R:S176	14.0799	7.13	No	No	0	4	5
67	R:R:L174	R:R:Y119	10.4122	2.34	No	Yes	0	4	6
68	R:R:F285	R:R:Y185	27.9223	12.38	Yes	Yes	3	5	7
69	R:R:I207	R:R:Y212	29.7377	4.84	No	Yes	0	6	5
70	R:R:I270	R:R:N313	24.1596	7.08	Yes	Yes	7	8	9
71	R:R:I270	R:R:V266	20.4496	3.07	Yes	No	0	8	8
72	R:R:S320	R:R:V266	18.935	3.23	No	No	0	7	8
73	R:R:R262	R:R:S320	17.4679	2.64	No	No	0	8	7
74	R:R:R262	R:R:R325	12.8292	2.13	No	No	0	8	9
75	R:R:D38	R:R:S35	14.7026	2.94	No	No	0	1	5
76	R:R:F173	R:R:V123	24.5607	3.93	Yes	No	0	6	5
77	R:R:F173	R:R:P183	21.4523	4.33	Yes	No	0	6	4
78	R:R:F285	R:R:I207	30.8143	3.77	Yes	No	0	5	6
79	R:R:L211	R:R:Y212	29.801	8.21	Yes	Yes	0	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 6LI1

PDB Summary
PDB	6LI1
Class	A
SubFamily	Orphan
Type	A orphans
SubType	GPR52
Species	Homo sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.9
Date	2020-02-26
D.O.I.	10.1038/s41586-020-2019-0

Net Summary
I_min	3.77
Number of Linked Nodes	275
Number of Links	308
Number of Hubs	43
Number of Links mediated by Hubs	166
Number of Communities	9
Number of Nodes involved in Communities	53
Number of Links involved in Communities	71

Path Summary
Number Of Nodes in MetaPath	80
Number Of Links MetaPath	79
Number of Shortest Paths	51760
Length Of Smallest Path	3
Average Path Length	13.569
Length of Longest Path	30
Minimum Path Strength	1.35
Average Path Strength	6.57159
Maximum Path Strength	22.7
Minimum Path Correlation	0.7
Average Path Correlation	0.93337
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4.34783
Average % Of Corr. Nodes	52.783
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.5156
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9Y2T5
Sequence	>6LI1_Chain_R R H S C P L G F G H Y S V V D V C I F E T V V I V L L T F L I I A G N L T V I F V F H C A P L L H H Y T T S Y F I Q T M A Y A D L F V G V S C L V P T L S L L H Y S T G V H E S L T C Q V F G Y I I S V L K S V S M W C L A C I S V D R Y L A I T K P L S Y N Q L V T P C R L R I C I I L I W I Y S C L I F L P S F F G W G K P G Y H G D I F E W C A T S W L T S A Y F T G F I V C L L Y A P A A F V V C F T Y F H I F K I C R Q H T K E R R Y L M V L F R I T S V F Y M L Q L P Y I I Y F L L E S S R V L D N P T L S F L T T W L A I S N S F C N P V I Y A L S D S T F R L G L R R L S E T M C T S C M C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6LI0	A	Orphan	A orphans	GPR52	Homo sapiens	-	GTPL9804	-	2.2	2020-02-26	10.1038/s41586-020-2019-0
	6LI1	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	-	2.9	2020-02-26	10.1038/s41586-020-2019-0
	6LI2	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	-	2.8	2020-02-26	10.1038/s41586-020-2019-0
	6LI3	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.32	2020-02-26	10.1038/s41586-020-2019-0
	8HMP	A	Orphan	A orphans	GPR52	Homo sapiens	-	PubChem 69921479	Gs/&β;1/&γ;2	2.77	2023-06-21	10.1002/mco2.260

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 6LI1.zip

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