psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D38	R:R:F42	3.58	No	No	0	1	4
2	R:R:C40	R:R:E43	3.04	No	No	0	4	5
3	R:R:I41	R:R:T44	3.04	No	Yes	0	6	6
4	R:R:E43	R:R:F300	5.83	No	No	0	5	4
5	R:R:T44	R:R:V45	3.17	Yes	No	0	6	6
6	R:R:I47	R:R:T98	6.08	No	Yes	0	5	6
7	R:R:I47	R:R:W304	7.05	No	Yes	0	5	4
8	R:R:T98	R:R:V48	4.76	Yes	No	0	6	4
9	R:R:L50	R:R:S308	3	No	No	0	6	6
10	R:R:C94	R:R:T51	3.38	No	No	0	7	6
11	R:R:F311	R:R:I54	11.3	Yes	No	0	6	7
12	R:R:F311	R:R:G57	3.01	Yes	No	0	6	8
13	R:R:D87	R:R:N58	4.04	No	No	4	9	9
14	R:R:L88	R:R:N58	4.12	No	No	0	6	9
15	R:R:F311	R:R:N58	6.04	Yes	No	4	6	9
16	R:R:I62	R:R:Y85	8.46	No	No	0	8	6
17	R:R:F324	R:R:V64	6.55	No	No	0	8	8
18	R:R:F65	R:R:L71	6.09	No	No	5	7	8
19	R:R:F65	R:R:S77	6.61	No	No	5	7	8
20	R:R:F65	R:R:Q81	14.05	No	No	0	7	6
21	R:R:C67	R:R:L331	4.76	No	No	0	5	6
22	R:R:L70	R:R:L71	4.15	No	No	0	5	8
23	R:R:L71	R:R:S77	3	No	No	5	8	8
24	R:R:H73	R:R:P155	7.63	No	No	0	7	3
25	R:R:S77	R:R:Y74	3.82	No	No	0	8	4
26	R:R:T75	R:R:T76	3.14	No	No	0	6	8
27	R:R:D138	R:R:T75	11.56	No	No	0	9	6
28	R:R:L158	R:R:Y78	3.52	No	Yes	0	7	4
29	R:R:R159	R:R:Y78	3.09	No	Yes	0	3	4
30	R:R:I162	R:R:Y78	3.63	No	Yes	0	8	4
31	R:R:C134	R:R:F79	8.38	No	Yes	0	6	8
32	R:R:F79	R:R:I135	5.02	Yes	No	0	8	9
33	R:R:F79	R:R:L158	3.65	Yes	No	0	8	7
34	R:R:F79	R:R:I162	6.28	Yes	No	0	8	8
35	R:R:Q81	R:R:Y85	11.27	No	No	0	6	6
36	R:R:C131	R:R:T82	3.38	No	No	0	8	9
37	R:R:I162	R:R:T82	7.6	No	No	0	8	9
38	R:R:M83	R:R:P314	5.03	No	No	0	9	9
39	R:R:D87	R:R:F311	3.58	No	Yes	4	9	6
40	R:R:D87	R:R:P314	3.22	No	No	0	9	9
41	R:R:G91	R:R:V90	3.68	No	No	0	6	8
42	R:R:L124	R:R:V90	5.96	No	No	0	7	8
43	R:R:K125	R:R:V90	9.11	No	No	0	6	8
44	R:R:I121	R:R:S93	4.64	No	No	0	6	4
45	R:R:P97	R:R:V96	5.3	No	No	0	4	7
46	R:R:F117	R:R:P97	8.67	Yes	No	0	5	4
47	R:R:L101	R:R:L102	4.15	No	No	0	4	4
48	R:R:H103	R:R:S105	5.58	No	No	0	4	4
49	R:R:G107	R:R:H109	3.18	No	No	0	7	6
50	R:R:C114	R:R:E110	4.56	No	No	3	9	7
51	R:R:E110	R:R:F190	9.33	No	Yes	3	7	3
52	R:R:C193	R:R:E110	4.56	No	No	3	9	7
53	R:R:S111	R:R:W192	3.71	No	No	0	3	4
54	R:R:C114	R:R:F190	5.59	No	Yes	3	9	3
55	R:R:C114	R:R:C193	7.28	No	No	3	9	9
56	R:R:F177	R:R:Q115	10.54	No	No	0	5	6
57	R:R:F117	R:R:G118	3.01	Yes	No	0	5	5
58	R:R:F117	R:R:I121	6.28	Yes	No	0	5	6
59	R:R:F117	R:R:G187	3.01	Yes	No	0	5	4
60	R:R:C170	R:R:Y119	5.38	No	No	0	4	6
61	R:R:F173	R:R:S122	6.61	Yes	No	0	6	5
62	R:R:H186	R:R:S122	5.58	Yes	No	0	2	5
63	R:R:S169	R:R:V123	3.23	No	No	0	8	5
64	R:R:F173	R:R:V123	3.93	Yes	No	0	6	5
65	R:R:I307	R:R:K125	4.36	No	No	0	6	6
66	R:R:K125	R:R:S310	6.12	No	No	0	6	9
67	R:R:S126	R:R:S169	3.26	No	No	0	6	8
68	R:R:L211	R:R:S126	6.01	No	No	0	7	6
69	R:R:V127	R:R:W166	3.68	No	No	0	6	9
70	R:R:S169	R:R:V127	3.23	No	No	0	8	6
71	R:R:M129	R:R:Y212	7.18	No	Yes	2	7	5
72	R:R:M129	R:R:W278	13.96	No	Yes	2	7	8
73	R:R:I165	R:R:W130	9.4	No	No	0	6	5
74	R:R:L211	R:R:W130	9.11	No	No	0	7	5
75	R:R:F274	R:R:L132	9.74	Yes	No	0	9	8
76	R:R:L132	R:R:Y317	7.03	No	No	0	8	9
77	R:R:I135	R:R:R139	3.76	No	No	0	9	9
78	R:R:S136	R:R:V219	6.46	No	No	6	8	5
79	R:R:S136	R:R:Y223	6.36	No	Yes	6	8	9
80	R:R:D138	R:R:Y149	9.2	No	Yes	0	9	8
81	R:R:R139	R:R:Y223	5.14	No	Yes	0	9	9
82	R:R:L267	R:R:R139	4.86	No	No	0	8	9
83	R:R:T144	R:R:Y140	9.99	No	No	0	6	8
84	R:R:T222	R:R:Y140	6.24	No	No	0	7	8
85	R:R:L141	R:R:Y149	7.03	No	Yes	0	5	8
86	R:R:A142	R:R:Y149	6.67	No	Yes	0	8	8
87	R:R:K145	R:R:T144	3	No	No	0	6	6
88	R:R:K145	R:R:S148	3.06	No	No	0	6	5
89	R:R:V153	R:R:Y149	12.62	No	Yes	0	7	8
90	R:R:L158	R:R:V153	4.47	No	No	0	7	7
91	R:R:P155	R:R:T154	3.5	No	No	0	3	8
92	R:R:C156	R:R:T154	5.07	No	No	0	4	8
93	R:R:R157	R:R:T154	11.64	No	No	0	5	8
94	R:R:I172	R:R:Y168	4.84	No	No	0	5	4
95	R:R:L210	R:R:Y168	5.86	No	No	0	5	4
96	R:R:F173	R:R:I172	7.54	Yes	No	0	6	5
97	R:R:F173	R:R:S176	5.28	Yes	No	0	6	5
98	R:R:P175	R:R:W180	4.05	No	No	0	6	6
99	R:R:P183	R:R:S176	5.34	No	No	0	4	5
100	R:R:F203	R:R:S176	5.28	Yes	No	0	5	5
101	R:R:F203	R:R:G181	4.52	Yes	No	0	5	6
102	R:R:K182	R:R:P183	5.02	Yes	No	1	3	4
103	R:R:K182	R:R:Y185	8.36	Yes	Yes	1	3	7
104	R:R:D188	R:R:K182	8.3	No	Yes	1	4	3
105	R:R:K182	R:R:W197	18.57	Yes	No	1	3	5
106	R:R:K182	R:R:T199	9.01	Yes	No	1	3	3
107	R:R:P183	R:R:W197	5.4	No	No	1	4	5
108	R:R:G184	R:R:H186	3.18	No	Yes	0	2	2
109	R:R:F285	R:R:G184	4.52	Yes	No	0	5	2
110	R:R:D188	R:R:Y185	9.2	No	Yes	1	4	7
111	R:R:T199	R:R:Y185	3.75	No	Yes	1	3	7
112	R:R:F285	R:R:Y185	9.28	Yes	Yes	0	5	7
113	R:R:E288	R:R:Y185	10.1	No	Yes	1	3	7
114	R:R:H186	R:R:Y281	8.71	Yes	Yes	0	2	6
115	R:R:H186	R:R:I307	3.98	Yes	No	0	2	6
116	R:R:G187	R:R:W304	4.22	No	Yes	0	4	4
117	R:R:A194	R:R:D188	4.63	No	No	0	4	4
118	R:R:F300	R:R:I189	7.54	No	No	0	4	4
119	R:R:C193	R:R:F190	9.78	No	Yes	3	9	3
120	R:R:S196	R:R:W192	19.77	No	No	0	3	4
121	R:R:L198	R:R:R291	4.86	No	No	0	5	1
122	R:R:E288	R:R:T199	12.7	No	No	1	3	3
123	R:R:S200	R:R:Y202	5.09	No	No	0	3	6
124	R:R:F203	R:R:I207	6.28	Yes	No	0	5	6
125	R:R:F285	R:R:T204	5.19	Yes	No	0	5	5
126	R:R:S289	R:R:T204	3.2	No	No	0	4	5
127	R:R:V208	R:R:Y212	7.57	No	Yes	0	4	5
128	R:R:L211	R:R:Y212	3.52	No	Yes	0	7	5
129	R:R:W278	R:R:Y212	4.82	Yes	Yes	2	8	5
130	R:R:Y212	R:R:Y281	5.96	Yes	Yes	2	5	6
131	R:R:I282	R:R:Y212	4.84	No	Yes	2	6	5
132	R:R:A213	R:R:P214	3.74	No	No	0	5	9
133	R:R:F217	R:R:F221	5.36	No	No	0	6	4
134	R:R:F221	R:R:V218	5.24	No	No	0	4	8
135	R:R:V219	R:R:Y223	3.79	No	Yes	6	5	9
136	R:R:T222	R:R:Y223	3.75	No	Yes	0	7	9
137	R:R:I226	R:R:Y223	4.84	No	Yes	0	9	9
138	R:R:F268	R:R:Y223	4.13	No	Yes	0	5	9
139	R:R:T271	R:R:Y223	11.24	No	Yes	0	8	9
140	R:R:F227	R:R:F268	13.93	No	No	0	7	5
141	R:R:E236	R:R:K235	4.05	No	No	0	5	6
142	R:R:D239	R:R:R243	3.57	No	No	0	4	4
143	R:R:H247	R:R:R241	3.39	No	No	0	2	4
144	R:R:F244	R:R:R243	3.21	No	No	0	3	4
145	R:R:L267	R:R:S320	6.01	No	No	0	8	7
146	R:R:I270	R:R:R269	12.53	No	No	0	8	7
147	R:R:I270	R:R:I316	8.83	No	No	0	8	8
148	R:R:I270	R:R:Y317	6.04	No	No	0	8	9
149	R:R:F274	R:R:T271	5.19	Yes	No	0	9	8
150	R:R:F274	R:R:W278	5.01	Yes	Yes	0	9	8
151	R:R:F274	R:R:N313	3.62	Yes	No	0	9	9
152	R:R:L277	R:R:N309	9.61	No	Yes	0	8	9
153	R:R:W278	R:R:Y281	7.72	Yes	Yes	2	8	6
154	R:R:I282	R:R:Y281	3.63	No	Yes	2	6	6
155	R:R:F285	R:R:Y281	15.47	Yes	Yes	0	5	6
156	R:R:L287	R:R:Y284	4.69	No	No	0	4	4
157	R:R:S299	R:R:Y284	13.99	No	No	0	4	4
158	R:R:E288	R:R:R291	9.3	No	No	0	3	1
159	R:R:L293	R:R:V292	4.47	No	No	0	1	3
160	R:R:D294	R:R:P296	4.83	No	No	0	3	2
161	R:R:N295	R:R:P296	3.26	No	No	0	3	2
162	R:R:L298	R:R:N295	8.24	No	No	0	4	3
163	R:R:F300	R:R:W304	13.03	No	Yes	0	4	4
164	R:R:I307	R:R:W304	3.52	No	Yes	0	6	4
165	R:R:L305	R:R:N309	5.49	No	Yes	0	7	9
166	R:R:N309	R:R:S308	4.47	Yes	No	0	9	6
167	R:R:F311	R:R:V315	3.93	Yes	No	0	6	7
168	R:R:N313	R:R:P314	3.26	No	No	0	9	9
169	R:R:F324	R:R:S318	10.57	No	No	0	8	7
170	R:R:L319	R:R:R325	9.72	No	No	0	5	9
171	R:R:G327	R:R:R330	3	No	No	0	7	5
172	R:R:L328	R:R:S332	3	No	No	0	7	5
173	R:R:L328	R:R:V64	2.98	No	No	0	7	8
174	R:R:L287	R:R:V292	2.98	No	No	0	4	3
175	R:R:L101	R:R:T44	2.95	No	Yes	0	4	6
176	R:R:D38	R:R:V39	2.92	No	No	0	1	4
177	R:R:N295	R:R:T297	2.92	No	No	0	3	1
178	R:R:F203	R:R:P175	2.89	Yes	No	0	5	6
179	R:R:E43	R:R:V39	2.85	No	No	0	5	4
180	R:R:I282	R:R:L286	2.85	No	No	0	6	5
181	R:R:L49	R:R:L50	2.77	No	No	0	4	6
182	R:R:A216	R:R:Y275	2.67	No	No	0	4	5
183	R:R:L112	R:R:Q115	2.66	No	No	0	1	6
184	R:R:H233	R:R:I229	2.65	No	No	0	7	6
185	R:R:F203	R:R:S200	2.64	Yes	No	0	5	3
186	R:R:C94	R:R:W304	2.61	No	Yes	0	7	4
187	R:R:F52	R:R:I55	2.51	No	No	0	5	6
188	R:R:F206	R:R:L210	2.44	No	No	0	5	5
189	R:R:F324	R:R:L319	2.44	No	No	0	8	5
190	R:R:T303	R:R:W304	2.43	No	Yes	0	5	4
191	R:R:L331	R:R:R330	2.43	No	No	0	6	5
192	R:R:E191	R:R:F190	2.33	No	Yes	0	3	3
193	R:R:Q81	R:R:Y78	2.25	No	Yes	0	6	4
194	R:R:H225	R:R:Y140	2.18	No	No	0	5	8
195	R:R:F244	R:R:R240	2.14	No	No	0	3	3
196	R:R:F173	R:R:Y119	2.06	Yes	No	0	6	6
197	R:R:F178	R:R:W180	2	No	No	0	5	6
198	R:R:A56	R:R:G57	1.95	No	No	0	4	8
199	R:R:A68	R:R:P69	1.87	No	No	0	6	6
200	R:R:G205	R:R:V208	1.84	No	No	0	4	4
201	R:R:G57	R:R:T60	1.82	No	No	0	8	6
202	R:R:C134	R:R:C161	1.82	No	No	0	6	6
203	R:R:P97	R:R:S100	1.78	No	No	0	4	4
204	R:R:G91	R:R:I55	1.76	No	No	0	6	6
205	R:R:P280	R:R:T302	1.75	No	No	0	9	5
206	R:R:A201	R:R:S289	1.71	No	No	0	4	4
207	R:R:G327	R:R:L326	1.71	No	No	0	7	4
208	R:R:A84	R:R:V61	1.7	No	No	0	9	9
209	R:R:A86	R:R:V127	1.7	No	No	0	8	6
210	R:R:A133	R:R:V218	1.7	No	No	0	7	8
211	R:R:C336	R:R:T337	1.69	No	No	0	4	4
212	R:R:K145	R:R:P146	1.67	No	No	0	6	8
213	R:R:L70	R:R:P69	1.64	No	No	0	5	6
214	R:R:L174	R:R:P175	1.64	No	No	0	4	6
215	R:R:L279	R:R:P280	1.64	No	No	0	6	9
216	R:R:S128	R:R:S310	1.63	No	No	0	9	9
217	R:R:A84	R:R:I62	1.62	No	No	0	9	8
218	R:R:S290	R:R:V292	1.62	No	No	0	4	3
219	R:R:S318	R:R:V315	1.62	No	No	0	7	7
220	R:R:V218	R:R:V219	1.6	No	No	0	8	5
221	R:R:S272	R:R:T271	1.6	No	No	0	5	8
222	R:R:C209	R:R:L210	1.59	No	No	0	4	5
223	R:R:T44	R:R:T98	1.57	Yes	Yes	0	6	6
224	R:R:T302	R:R:T303	1.57	No	No	0	5	5
225	R:R:C312	R:R:N309	1.57	No	Yes	0	5	9
226	R:R:I54	R:R:S308	1.55	No	No	0	7	6
227	R:R:I120	R:R:S93	1.55	No	No	0	5	4
228	R:R:C336	R:R:E333	1.52	No	No	0	4	4
229	R:R:L112	R:R:S111	1.5	No	No	0	1	3
230	R:R:L147	R:R:S148	1.5	No	No	0	7	5
231	R:R:L50	R:R:V46	1.49	No	No	0	6	4
232	R:R:L70	R:R:V323	1.49	No	No	0	5	7
233	R:R:L95	R:R:V92	1.49	No	No	0	7	4
234	R:R:L267	R:R:V266	1.49	No	No	0	8	8
235	R:R:N313	R:R:V273	1.48	No	No	0	9	7
236	R:R:N321	R:R:V323	1.48	No	No	0	8	7
237	R:R:I135	R:R:I80	1.47	No	No	0	9	8
238	R:R:L95	R:R:T98	1.47	No	Yes	0	7	6
239	R:R:L99	R:R:T98	1.47	No	Yes	0	6	6
240	R:R:I143	R:R:I229	1.47	No	No	0	9	6
241	R:R:L331	R:R:T334	1.47	No	No	0	6	5
242	R:R:N238	R:R:T234	1.46	No	No	0	3	5
243	R:R:F244	R:R:P245	1.44	No	No	0	3	3
244	R:R:I167	R:R:L171	1.43	No	No	0	4	4
245	R:R:I172	R:R:L171	1.43	No	No	0	5	4
246	R:R:I283	R:R:L279	1.43	No	No	0	5	6
247	R:R:A194	R:R:F190	1.39	No	Yes	0	4	3
248	R:R:L49	R:R:L53	1.38	No	No	0	4	5
249	R:R:L59	R:R:L88	1.38	No	No	0	5	6
250	R:R:L141	R:R:L152	1.38	No	No	0	5	4
251	R:R:L301	R:R:L305	1.38	No	No	0	3	7
252	R:R:F89	R:R:V92	1.31	No	No	0	7	4
253	R:R:I237	R:R:R241	1.25	No	No	0	7	4
254	R:R:S196	R:R:W197	1.24	No	No	0	3	5
255	R:R:L152	R:R:R157	1.21	No	No	0	4	5
256	R:R:N238	R:R:R241	1.21	No	No	0	3	4
257	R:R:H72	R:R:H73	1.19	No	No	0	8	7
258	R:R:D294	R:R:Y284	1.15	No	No	0	3	4
259	R:R:F224	R:R:H225	1.13	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:T44	2.6825	4	0	6
2	R:R:Y78	3.1225	4	0	4
3	R:R:F79	5.8325	4	0	8
4	R:R:T98	3.07	5	0	6
5	R:R:F117	5.2425	4	0	5
6	R:R:Y149	8.88	4	0	8
7	R:R:F173	5.084	5	0	6
8	R:R:K182	9.852	5	1	3
9	R:R:Y185	8.138	5	1	7
10	R:R:H186	5.3625	4	0	2
11	R:R:F190	5.684	5	3	3
12	R:R:F203	4.322	5	0	5
13	R:R:Y212	5.64833	6	2	5
14	R:R:Y223	5.60714	7	6	9
15	R:R:F274	5.89	4	0	9
16	R:R:W278	7.8775	4	2	8
17	R:R:Y281	8.298	5	2	6
18	R:R:F285	8.615	4	0	5
19	R:R:W304	5.47667	6	0	4
20	R:R:N309	5.285	4	0	9
21	R:R:F311	5.572	5	4	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F300	R:R:W304	13.2189	13.03	No	Yes	0	4	4
2	R:R:I47	R:R:W304	22.2164	7.05	No	Yes	0	5	4
3	R:R:I47	R:R:T98	20.4469	6.08	No	Yes	0	5	6
4	R:R:I307	R:R:W304	60.1035	3.52	No	Yes	0	6	4
5	R:R:H186	R:R:I307	72.0852	3.98	Yes	No	0	2	6
6	R:R:H186	R:R:Y281	75.2193	8.71	Yes	Yes	0	2	6
7	R:R:W278	R:R:Y281	87.411	7.72	Yes	Yes	2	8	6
8	R:R:F274	R:R:W278	100	5.01	Yes	Yes	0	9	8
9	R:R:F274	R:R:N313	46.4797	3.62	Yes	No	0	9	9
10	R:R:N313	R:R:P314	43.9154	3.26	No	No	0	9	9
11	R:R:D87	R:R:P314	41.2911	3.22	No	No	0	9	9
12	R:R:D87	R:R:F311	35.3453	3.58	No	Yes	4	9	6
13	R:R:F311	R:R:I54	18.1375	11.3	Yes	No	0	6	7
14	R:R:I54	R:R:S308	16.5629	1.55	No	No	0	7	6
15	R:R:F274	R:R:T271	90.5676	5.19	Yes	No	0	9	8
16	R:R:T271	R:R:Y223	89.4729	11.24	No	Yes	0	8	9
17	R:R:R139	R:R:Y223	76.0816	5.14	No	Yes	0	9	9
18	R:R:I135	R:R:R139	72.5725	3.76	No	No	0	9	9
19	R:R:F79	R:R:I135	70.7281	5.02	Yes	No	0	8	9
20	R:R:F79	R:R:L158	42.4008	3.65	Yes	No	0	8	7
21	R:R:L158	R:R:Y78	23.8434	3.52	No	Yes	0	7	4
22	R:R:Q81	R:R:Y78	40.0915	2.25	No	Yes	0	6	4
23	R:R:Q81	R:R:Y85	11.7493	11.27	No	No	0	6	6
24	R:R:F79	R:R:I162	26.1153	6.28	Yes	No	0	8	8
25	R:R:I162	R:R:Y78	22.4038	3.63	No	Yes	0	8	4
26	R:R:F311	R:R:V315	13.3688	3.93	Yes	No	0	6	7
27	R:R:S318	R:R:V315	11.7493	1.62	No	No	0	7	7
28	R:R:F324	R:R:S318	10.1147	10.57	No	No	0	8	7
29	R:R:F65	R:R:Q81	26.1078	14.05	No	No	0	7	6
30	R:R:F65	R:R:L71	17.4477	6.09	No	No	5	7	8
31	R:R:L70	R:R:L71	14.651	4.15	No	No	0	5	8
32	R:R:L158	R:R:V153	21.4066	4.47	No	No	0	7	7
33	R:R:V153	R:R:Y149	19.9745	12.62	No	Yes	0	7	8
34	R:R:L141	R:R:Y149	12.589	7.03	No	Yes	0	5	8
35	R:R:L141	R:R:L152	11.067	1.38	No	No	0	5	4
36	R:R:I307	R:R:K125	14.9959	4.36	No	No	0	6	6
37	R:R:G187	R:R:W304	16.7954	4.22	No	Yes	0	4	4
38	R:R:F117	R:R:G187	14.9959	3.01	Yes	No	0	5	4
39	R:R:A194	R:R:F190	10.1897	1.39	No	Yes	0	4	3
40	R:R:A194	R:R:D188	12.1841	4.63	No	No	0	4	4
41	R:R:D188	R:R:Y185	12.2741	9.2	No	Yes	1	4	7
42	R:R:F285	R:R:Y185	35.5552	9.28	Yes	Yes	0	5	7
43	R:R:G184	R:R:H186	10.2347	3.18	No	Yes	0	2	2
44	R:R:F285	R:R:Y281	34.2131	15.47	Yes	Yes	0	5	6
45	R:R:H186	R:R:S122	33.4858	5.58	Yes	No	0	2	5
46	R:R:F173	R:R:S122	32.2861	6.61	Yes	No	0	6	5
47	R:R:F173	R:R:S176	20.132	5.28	Yes	No	0	6	5
48	R:R:S196	R:R:W197	14.2536	1.24	No	No	0	3	5
49	R:R:S196	R:R:W192	11.9142	19.77	No	No	0	3	4
50	R:R:K182	R:R:Y185	15.8506	8.36	Yes	Yes	1	3	7
51	R:R:K182	R:R:W197	12.694	18.57	Yes	No	1	3	5
52	R:R:L211	R:R:Y212	10.812	3.52	No	Yes	0	7	5
53	R:R:T222	R:R:Y223	14.9734	3.75	No	Yes	0	7	9
54	R:R:T222	R:R:Y140	13.3688	6.24	No	No	0	7	8
55	R:R:F173	R:R:I172	11.9592	7.54	Yes	No	0	6	5
56	R:R:F203	R:R:S176	14.9734	5.28	Yes	No	0	5	5
57	R:R:W278	R:R:Y212	12.3791	4.82	Yes	Yes	2	8	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 6LI3_nogp

PDB Summary
PDB	6LI3_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3
Number of Linked Nodes	254
Number of Links	259
Number of Hubs	21
Number of Links mediated by Hubs	90
Number of Communities	6
Number of Nodes involved in Communities	25
Number of Links involved in Communities	32

Path Summary
Number Of Nodes in MetaPath	58
Number Of Links MetaPath	57
Number of Shortest Paths	27048
Length Of Smallest Path	3
Average Path Length	12.631
Length of Longest Path	28
Minimum Path Strength	1.23
Average Path Strength	5.693
Maximum Path Strength	13.79
Minimum Path Correlation	0.7
Average Path Correlation	0.949311
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	6.25
Average % Of Corr. Nodes	61.6817
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.5233
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9Y2T5
Sequence	>6LI3_nogp_Chain_R V D V C I F E T V V I V L L T F L I I A G N L T V I F V F H C A P L L H H Y T T S Y F I Q T M A Y A D L F V G V S C L V P T L S L L H Y S T G V H E S L T C Q V F G Y I I S V L K S V S M W C L A C I S V D R Y L A I T K P L S Y N Q L V T P C R L R I C I I L I W I Y S C L I F L P S F F G W G K P G Y H G D I F E W C A T S W L T S A Y F T G F I V C L L Y A P A A F V V C F T Y F H I F K I C R Q H T K E I N D R R A R F P S H M V L F R I T S V F Y M L W L P Y I I Y F L L E S S R V L D N P T L S F L T T W L A I S N S F C N P V I Y S L S N S V F R L G L R R L S E T M C T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8HMP	A	Orphan	Orphan	GPR52	Homo sapiens	-	C17	Gs/β1/γ2	2.77	2023-06-21	doi.org/10.1002/mco2.260
	8HMP (No Gprot)	A	Orphan	Orphan	GPR52	Homo sapiens	-	C17		2.77	2023-06-21	doi.org/10.1002/mco2.260
	6LI0	A	Orphan	Orphan	GPR52	Homo sapiens	-	C17	-	2.2	2020-02-26	doi.org/10.1038/s41586-020-2019-0
	6LI1	A	Orphan	Orphan	GPR52	Homo sapiens	-	-	-	2.9	2020-02-26	doi.org/10.1038/s41586-020-2019-0
	6LI2	A	Orphan	Orphan	GPR52	Homo sapiens	-	-	-	2.8	2020-02-26	doi.org/10.1038/s41586-020-2019-0
	6LI3	A	Orphan	Orphan	GPR52	Homo sapiens	-	-	Gs/β1/γ2	3.32	2020-02-26	doi.org/10.1038/s41586-020-2019-0
	6LI3 (No Gprot)	A	Orphan	Orphan	GPR52	Homo sapiens	-	-		3.32	2020-02-26	doi.org/10.1038/s41586-020-2019-0

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 6LI3_nogp.zip

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