Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1E:E:P19 4.124300
2E:E:Y24 2.90754430
3E:E:M27 8.0254430
4E:E:M34 5.7275400
5E:E:I41 5.9825550
6E:E:P54 4.755400
7E:E:F57 6.6665550
8E:E:W65 7.526500
9E:E:E77 6.7725120
10E:E:L84 4.954120
11E:E:M85 3.6585430
12E:E:Y90 10.04754430
13E:E:F92 5.85400
14E:E:H97 6.395230
15E:E:V98 3.185400
16E:E:Y108 6.12400
17E:E:R109 4.6125400
18E:E:Q111 4.1225310
19E:E:T112 4.0285310
20E:E:F115 12.9565310
21E:E:Y128 4.67500
22E:E:R135 3.72400
23E:E:M137 3.394690
24E:E:Y148 9.3645230
25E:E:E149 10.0945230
26E:E:F160 4.314680
27E:E:W164 6.7275400
28E:E:E172 4.04254690
29E:E:R186 10.9175400
30E:E:R194 8.55754230
31E:E:F196 13.40754310
32E:E:W197 5.398500
33E:E:K215 5.2385100
34E:E:L291 6.35254250
35E:E:D294 7.6175400
36E:E:F296 4.41754190
37E:E:L297 5.2645250
38E:E:W306 4.89667670
39E:E:F313 5.78470
40E:E:W314 9.4525470
41E:E:R326 7.9445440
42E:E:W330 7.784440
43E:E:F332 6.6125400
44E:E:M334 10.36400
45E:E:D340 9.3445440
46E:E:V342 6.2254440
47E:E:W363 9.2954340
48E:E:P373 4.864560
49E:E:R380 8.125440
50E:E:V381 4.594540
51E:E:Q382 3.58440
52E:E:I384 5.9440
53E:E:W385 9.88143740
54E:E:E387 9.44440
55E:E:L389 8.32333640
56E:E:I397 6.3075440
57E:E:L399 6.282540
58E:E:Y404 6.56167640
59E:E:K406 9.29400
60E:E:T407 5.305640
61E:E:P414 6.184540
62E:E:T418 6.9725440
63E:E:F419 8.0175440
64E:E:I426 7.6054340
65E:E:M430 6.0654340
66E:E:Y435 8.8385330
67E:E:Y444 7.70754330
68F:F:V78 3.82404
69F:F:E79 7.6425324
70F:F:L80 4.2754325
71F:F:L90 6.4054254
72F:F:F93 5.194503
73F:F:H104 6.368509
74F:F:W113 6.7025478
75F:F:D126 6.8925409
76F:F:W132 11.3865729
77F:F:D133 7.9675478
78F:F:F135 5.486574
79F:F:M145 6.41254738
80F:F:W149 15.9785109
81F:F:V150 5.99754739
82F:F:Y155 5.813336457
83F:F:K180 8.7145573
84F:F:N183 5.01754574
85F:F:K188 9.65754744
86F:F:Y197 6.9285108
87F:F:D207 4.655758
88F:F:M208 4.1745563
89F:F:Q209 9.74405
90F:F:T212 6.0054359
91F:F:S214 5.65254109
92F:F:G215 4.544108
93F:F:D216 10.3554109
94F:F:T218 8.91754107
95F:F:W222 9.41254359
96F:F:S226 5.6425406
97F:F:F233 12.3454467
98F:F:H236 9.2925409
99F:F:G257 1.9454207
100F:F:M264 6.4575407
101F:F:W266 12.175469
102F:F:D283 9.00754309
103F:F:I284 5.74254208
104F:F:R288 6.844574
105F:F:Y289 4.706506
106F:F:Y290 5.0285716
107F:F:R306 8.377147208
108F:F:D309 4.8125409
109F:F:E315 9.20754207
110F:F:Y319 3.5075406
111F:F:I324 5.576676124
112F:F:R338 6.27259
113F:F:L339 5.6725195
114F:F:F341 7.4245196
115F:F:Y344 9.6245128
116F:F:N345 8.015307
117F:F:D346 6.22254128
118F:F:Y347 6.79254124
119F:F:T348 5.74254125
120F:F:N350 9.191676126
121F:F:W352 5.1185129
122F:F:L355 4.1325257
123F:F:K356 2.8825406
124F:F:R359 11.28254126
125F:F:I362 9.2345124
126F:F:F364 6.87254124
127F:F:R374 6.32475
128F:F:P377 4.795472
129F:F:D378 8.66167678
130F:F:F382 9.90254195
131F:F:W387 14.9975408
132F:F:D388 7.794769
133F:F:W394 6.575198
134R:R:Q72 10.844774
135R:R:V82 7.74117
136R:R:L86 12.67754118
137R:R:Y87 9.9585116
138R:R:L94 9.76254119
139R:R:Y103 9.4585265
140R:R:K111 8.29754153
141R:R:L115 5.13754475
142R:R:F135 5.59408
143R:R:M139 4.76557
144R:R:Q148 11.87456
145R:R:D152 5.096556
146R:R:D153 7.816559
147R:R:W156 16.364509
148R:R:Y157 6.424559
149R:R:L165 4.125176
150R:R:E168 6.56754178
151R:R:I176 6.878557
152R:R:F178 9.296556
153R:R:I201 7.0245179
154R:R:F263 18.7185476
155R:R:W265 13.635477
156R:R:S266 5.69254268
157R:R:P267 5.3625155
158R:R:Y269 13.1056265
159R:R:L270 16.274119
160R:R:S276 3.614114
161R:R:Y277 13.85336118
162R:R:W281 23.4685159
163R:R:V283 4.3575406
164R:R:T284 7.99754268
165R:R:L285 3.78754479
166R:R:I289 7.94558
167R:R:F300 15.634808
168R:R:V303 4.8125409
169R:R:D307 11.49254269
170R:R:L310 6.50754158
171R:R:Q317 4.3475409
172R:R:C318 6.09254499
173R:R:W323 11.04176159
174R:R:N334 5.9654817
175R:R:C337 5.01754499
176R:R:P339 5.194498
177R:R:F345 7.1465159
178R:R:Y350 4.9345499
179R:R:F358 10.5754827
180R:R:V391 2.19403
181R:R:C392 5.17254819
182R:R:F409 4.6625583
183R:R:E412 11.46754507
184R:R:R417 6.766509
185R:R:Q424 10.6354229
186R:R:M428 4.53754227
187R:R:S446 3.665408
188R:R:Y466 9.5265228
189R:R:F467 2.88254227
190R:R:R485 8.4375409
191R:R:R488 4.645409
192R:R:Y496 8.7845369
193R:R:K502 3.585409
194R:R:F510 4.7654869
195R:R:M521 6.21754858
196R:R:W544 8.1675409
197R:R:N551 3.36407
198R:R:Q561 2.985405
199R:R:W578 6.642509
200R:R:E586 8.765409
201R:R:L590 2.20254369
202R:R:P604 3.4085869
203R:R:E620 8.0625369
204R:R:I623 5.3325405
205R:R:F627 8.165409
206R:R:H628 6.6025408
207R:R:Q639 8.65754509
208R:R:Y647 7.2975405
209R:R:H650 6.3685369
210R:R:H652 9.066229
211R:R:L709 6.592529
212R:R:E712 8.79167627
213R:R:D713 7.598529
214R:R:D716 7.13627
215R:R:K719 5.592529
216R:R:K720 10.352529
217R:R:K731 13.7085519
218R:R:K743 3.714519
219R:R:K747 14.085519
220R:R:I754 6.57607
221R:R:R757 9.945429
222S:S:V82 9.162537
223S:S:S84 5.4875436
224S:S:Y85 16.0562838
225S:S:Q93 10.1237834
226S:S:Y103 16.515635
227S:S:L105 10.895405
228S:S:W112 2.83404
229S:S:P113 6.8654595
230S:S:L129 3.2254916
231S:S:M139 6.935407
232S:S:Q148 4.8875456
233S:S:D152 5.42333656
234S:S:D153 7.615459
235S:S:W156 16.796559
236S:S:Y157 5.376509
237S:S:W162 8.225487
238S:S:E166 5.20754488
239S:S:E168 6.435408
240S:S:I171 8.51508
241S:S:R173 7.3545137
242S:S:F191 12.124928
243S:S:I201 7.45254489
244S:S:P211 5.40254924
245S:S:H212 9.6965133
246S:S:N215 7.10754137
247S:S:K264 11.00754134
248S:S:S266 6.5354138
249S:S:Y269 8.7485135
250S:S:L270 18.6075439
251S:S:Y277 10.0411938
252S:S:W281 21.05639
253S:S:L282 4.61254137
254S:S:T284 9.30754138
255S:S:I289 5.84378
256S:S:R301 13.2156378
257S:S:V303 5.9725409
258S:S:K305 9.9554138
259S:S:D307 9.554139
260S:S:L310 9.7875438
261S:S:Q311 10.024539
262S:S:C318 5.664169
263S:S:G322 3.48754605
264S:S:W323 7.6385599
265S:S:C337 3.9756169
266S:S:F345 6.136539
267S:S:Y350 7.815169
268S:S:F358 11.325407
269S:S:I420 3.86408
270S:S:E456 3.92254959
271S:S:I458 3.0375409
272S:S:G461 1.874619
273S:S:L464 2.8054618
274S:S:Y466 7.828577278
275S:S:Y496 5.7965389
276S:S:T498 3.805409
277S:S:T500 3.0975407
278S:S:W544 7.0225409
279S:S:I559 3.545408
280S:S:K563 3.0925404
281S:S:I569 2.7475405
282S:S:F570 3.875949
283S:S:W578 6.6275409
284S:S:E586 8.26754389
285S:S:L590 3.0054389
286S:S:V603 4.7775409
287S:S:E609 3.0485969
288S:S:E620 8.21754389
289S:S:F627 17.2475409
290S:S:H628 7.554388
291S:S:M643 3.795408
292S:S:Y647 7.99405
293S:S:F648 6.78254279
294S:S:H652 9.436676279
295S:S:T654 4.7875409
296C:C:P19 4.124398
297C:C:M27 8.0254528
298C:C:M34 5.7275408
299C:C:I41 5.6885628
300C:C:P54 4.755408
301C:C:F57 6.8725625
302C:C:W65 7.526506
303C:C:E77 6.7725149
304C:C:M85 3.6585526
305C:C:H88 6.234528
306C:C:Y90 10.04754529
307C:C:F92 5.85409
308C:C:H97 6.395189
309C:C:V98 3.185407
310C:C:Y108 6.3775408
311C:C:R109 4.69529
312C:C:Q111 4.122529
313C:C:T112 5.37571728
314C:C:Y114 7.354527
315C:C:F115 12.956527
316C:C:Y128 5.6085188
317C:C:M137 3.724879
318C:C:Q138 10.197541029
319C:C:R142 3.675409
320C:C:Y148 9.3645188
321C:C:E149 10.0945189
322C:C:F160 4.3141018
323C:C:W164 6.7275409
324C:C:F166 10.4954889
325C:C:E172 4.04254879
326C:C:V177 4.87528
327C:C:R181 10.168528
328C:C:E185 10.5875429
329C:C:R186 11.512541029
330C:C:L189 6.3975428
331C:C:Q192 5.902529
332C:C:R194 8.55754189
333C:C:F196 13.4075429
334C:C:W197 5.398509
335C:C:K215 5.238519
336C:C:Q261 6.83594
337C:C:W265 9.896595
338C:C:Q268 6.51595
339C:C:R273 8.932594
340C:C:M276 6.974284
341C:C:L291 6.35254291
342C:C:D294 7.6175409
343C:C:F296 4.41754214
344C:C:L297 5.88754294
345C:C:W306 4.89667688
346C:C:F313 5.78483
347C:C:W314 9.4525487
348C:C:P322 5.3265405
349C:C:R326 7.135409
350C:C:W330 7.0345409
351C:C:F332 6.6125408
352C:C:M334 10.36405
353C:C:D340 9.3445409
354C:C:V342 6.41254404
355C:C:W363 9.2954426
356C:C:R380 8.125466
357C:C:V381 4.594568
358C:C:Q382 3.58464
359C:C:I384 5.9469
360C:C:W385 9.88143766
361C:C:E387 9.44469
362C:C:L389 8.32333669
363C:C:I397 6.3075468
364C:C:L399 6.282567
365C:C:Y404 6.56167664
366C:C:K406 9.29403
367C:C:T407 5.305669
368C:C:P414 6.184566
369C:C:T418 6.9725465
370C:C:F419 8.0175465
371C:C:I426 7.6054428
372C:C:M430 6.0654429
373C:C:Y435 8.8385419
374C:C:Y444 7.70754419
375B:B:L64 7.758598
376B:B:K65 7.298596
377B:B:L68 6.912597
378B:B:E69 4.9925494
379B:B:E71 5.6425494
380B:B:E79 7.563336284
381B:B:L80 4.2754285
382B:B:L90 6.4054294
383B:B:F93 5.194503
384B:B:H104 6.368509
385B:B:W113 6.7025488
386B:B:W132 11.38651069
387B:B:D133 7.9675488
388B:B:F135 5.486584
389B:B:M145 6.412541078
390B:B:W149 15.978519
391B:B:V150 5.997541079
392B:B:Y155 5.813336537
393B:B:C171 2.5454248
394B:B:K180 8.7145633
395B:B:N183 5.01754634
396B:B:K188 9.657541084
397B:B:Y197 6.928518
398B:B:S202 4.555416
399B:B:F203 2.957541099
400B:B:T204 4.455415
401B:B:S206 4.792541055
402B:B:D207 5.322541098
403B:B:Q209 9.39405
404B:B:T212 6.0054249
405B:B:S214 5.6525419
406B:B:G215 4.54418
407B:B:D216 10.355419
408B:B:T218 8.9175417
409B:B:W222 9.41254249
410B:B:S226 5.6425406
411B:B:H236 7.234519
412B:B:S256 3.575419
413B:B:M264 6.4575407
414B:B:W266 11.676519
415B:B:T279 5.9954546
416B:B:D283 9.00754399
417B:B:R288 6.844584
418B:B:Y289 4.45451106
419B:B:Y290 5.02851046
420B:B:D302 7.4154649
421B:B:R306 7.218336548
422B:B:D309 4.8125409
423B:B:R314 9.65254287
424B:B:E315 9.564547
425B:B:Y319 3.5075406
426B:B:I324 5.576676144
427B:B:F326 4.215406
428B:B:R338 6.27299
429B:B:L339 5.6725215
430B:B:F341 7.4245216
431B:B:Y344 9.6245148
432B:B:N345 7.4985397
433B:B:D346 5.6254148
434B:B:Y347 6.79254144
435B:B:T348 5.74254145
436B:B:N350 9.191676146
437B:B:W352 5.1185149
438B:B:L355 4.1325297
439B:B:K356 2.8825406
440B:B:R359 11.28254146
441B:B:I362 9.2345144
442B:B:F364 6.87254144
443B:B:R374 6.32485
444B:B:P377 4.795482
445B:B:D378 8.66167688
446B:B:F382 9.90254215
447B:B:W387 14.9975408
448B:B:D388 7.7941119
449B:B:W394 6.575218
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1E:E:E77 E:E:I72 1005.47YesNo000
2E:E:I72 E:E:L70 1002.85NoNo000
3E:E:L70 E:E:W65 1002.28NoYes000
4E:E:E77 F:F:I362 1008.2YesYes1204
5E:E:I41 E:E:W65 1007.05YesYes000
6E:E:F57 E:E:I41 1008.79YesYes5500
7E:E:E149 E:E:Y148 10023.57YesYes2300
8E:E:V203 E:E:Y148 1006.31NoYes2300
9E:E:V203 E:E:V98 1004.81NoYes000
10E:E:D96 E:E:V98 1002.92NoYes000
11E:E:D96 E:E:P93 1003.22NoNo000
12E:E:P93 E:E:Y108 1002.78NoYes000
13E:E:F57 E:E:Y108 10010.32YesYes000
14F:F:N350 F:F:R359 10010.85YesYes1266
15E:E:H97 E:E:Y148 1008.71YesYes2300
16E:E:H97 E:E:R194 1009.03YesYes2300
17E:E:E149 E:E:R194 10010.47YesYes2300
18E:E:R194 E:E:Y131 10012.35YesNo000
19E:E:R135 E:E:Y131 1003.09YesNo000
20E:E:D190 E:E:R135 1005.96NoYes000
21E:E:D190 E:E:K134 1008.3NoNo000
22E:E:K134 E:E:Q174 1002.71NoNo000
23E:E:Q174 R:R:M755 1002.72NoNo007
24E:E:Q170 R:R:M755 1006.8NoNo007
25E:E:F166 E:E:Q170 10011.71NoNo000
26E:E:F166 E:E:M169 10011.2NoNo000
27E:E:M169 R:R:R744 1008.69NoNo009
28R:R:I754 R:R:L750 1008.56YesNo078
29R:R:L750 R:R:Y728 1005.86NoNo087
30R:R:K747 R:R:Y728 10039.41YesNo5197
31R:R:K747 R:R:R744 1004.95YesNo099
32E:E:D213 F:F:W149 10011.17NoYes1009
33F:F:Q125 F:F:W149 10024.09NoYes099
34F:F:N106 F:F:Q125 1005.28NoNo069
35F:F:D126 F:F:N106 1008.08YesNo096
36F:F:D126 F:F:K128 1004.15YesNo097
37F:F:I130 F:F:K128 1002.91NoNo087
38F:F:I130 F:F:W132 1009.4NoYes089
39F:F:I120 F:F:W132 1007.05NoYes059
40F:F:I120 F:F:S134 1003.1NoNo056
41E:E:W306 F:F:S134 1004.94YesNo706
42E:E:N304 E:E:W306 1004.52NoYes000
43E:E:L307 E:E:N304 1006.87NoNo000
44E:E:L307 F:F:R98 1009.72NoNo007
45F:F:A395 F:F:R98 1005.53NoNo087
46E:E:F296 F:F:A395 1002.77YesNo008
47E:E:D294 E:E:F296 1005.97YesYes000
48E:E:D294 E:E:L297 1009.5YesYes000
49E:E:L297 F:F:R338 1003.64YesYes2509
50F:F:L355 F:F:R338 1006.07YesYes2579
51F:F:L355 F:F:V354 1005.96YesNo075
52F:F:V354 F:F:Y319 1002.52NoYes056
53F:F:W352 F:F:Y319 1007.72YesYes096
54F:F:A395 F:F:M95 1004.83NoNo085
55F:F:F93 F:F:M95 10012.44YesNo035
56E:E:L297 F:F:F93 1004.87YesYes003
57E:E:D294 F:F:S336 10011.78YesNo009
58F:F:R338 F:F:S336 1003.95YesNo099
59E:E:D213 E:E:K215 1006.91NoYes1000
60E:E:K215 F:F:Y197 84.19143.58YesYes1008
61E:E:K215 F:F:L241 16.79362.82YesNo008
62F:F:L340 F:F:Y319 16.60582.34NoYes076
63F:F:F333 F:F:L340 16.36126.09NoNo087
64F:F:F333 F:F:Y290 15.60015.16NoYes7186
65F:F:S292 F:F:Y290 13.97772.54NoYes056
66F:F:D294 F:F:S292 11.65068.83NoNo035
67F:F:D294 F:F:G293 11.13443.35NoNo038
68F:F:G293 F:F:P247 10.87574.06NoNo084
69F:F:P247 F:F:Y289 10.6175.56NoYes046
70E:E:N304 E:E:P305 1003.26NoNo000
71E:E:F313 E:E:P305 1004.33YesNo700
72E:E:D301 E:E:F313 1007.17NoYes000
73E:E:D301 E:E:Q325 1005.22NoNo000
74E:E:P305 E:E:W314 10027.02NoYes700
75E:E:W306 F:F:R99 31.11565YesNo707
76E:E:W306 F:F:T380 1007.28YesNo705
77F:F:F135 F:F:R99 30.40724.28YesNo747
78E:E:W314 F:F:D378 1003.35YesYes708
79F:F:D378 F:F:T380 10013.01YesNo785
80E:E:E317 F:F:K117 1004.05NoNo005
81F:F:D378 F:F:K117 10013.83YesNo085
82E:E:Q325 E:E:S323 10011.55NoNo000
83E:E:R326 E:E:S323 1005.27YesNo000
84E:E:E317 E:E:R326 10015.12NoYes000
85E:E:P322 E:E:R326 1005.76NoYes000
86E:E:R326 E:E:V342 11.35125.23YesYes4400
87E:E:P322 E:E:V327 1003.53NoNo000
88E:E:D340 E:E:R326 1008.34YesYes4400
89E:E:L448 E:E:V327 1002.98NoNo000
90E:E:G331 E:E:Y444 63.53262.9NoYes3300
91E:E:L448 E:E:Y444 1005.86NoYes3300
92E:E:G331 E:E:Y435 61.2642.9NoYes3300
93E:E:I439 E:E:Y444 63.53269.67NoYes3300
94E:E:I439 E:E:Y435 61.26414.51NoYes3300
95E:E:M334 E:E:Y435 10016.76YesYes000
96E:E:D340 E:E:P341 1008.05YesNo000
97E:E:P341 E:E:R344 1002.88NoNo000
98E:E:L338 E:E:R344 1006.07NoNo000
99E:E:L338 E:E:W363 1003.42NoYes000
100E:E:M430 E:E:W363 1009.31YesYes3400
101E:E:M334 E:E:M430 52.22914.33YesYes000
102E:E:M334 E:E:S434 1003.07YesNo000
103E:E:F347 E:E:S434 1007.93NoNo000
104E:E:F347 E:E:L351 68.07476.09NoNo000
105E:E:F347 E:E:F438 34.039217.15NoNo000
106E:E:L351 E:E:L360 40.84594.15NoNo000
107E:E:F350 E:E:L351 20.42477.31NoNo000
108E:E:F350 E:E:F438 20.42369.65NoNo000
109E:E:E354 E:E:F350 27.23155.83NoNo000
110E:E:E354 E:E:S356 13.61584.31NoNo000
111E:E:I426 E:E:M430 1005.83YesYes3400
112E:E:I426 E:E:N359 22.71539.91YesNo3400
113E:E:E358 E:E:N359 20.44415.77NoNo000
114E:E:E358 E:E:R361 18.17253.49NoNo000
115E:E:R361 E:E:S357 15.9016.59NoNo000
116E:E:L360 E:E:L364 27.23158.3NoNo000
117E:E:F362 E:E:V366 1007.87NoNo000
118E:E:Q423 E:E:V366 10014.33NoNo000
119E:E:Q423 E:E:W363 10010.95NoYes000
120E:E:F362 E:E:I426 1007.54NoYes000
121E:E:F362 E:E:I397 1007.54NoYes000
122E:E:E367 E:E:L364 20.42437.95NoNo000
123E:E:A365 E:E:D368 15.8843.09NoNo000
124E:E:D368 E:E:E367 13.61936.5NoNo000
125E:E:D368 E:E:R380 18.16185.96NoYes000
126E:E:E383 E:E:R380 18.15659.3NoYes400
127E:E:E383 E:E:E387 22.69632.54NoYes400
128E:E:E387 E:E:F388 36.311922.15YesNo400
129E:E:F388 E:E:I397 45.396.28NoYes400
130E:E:I384 E:E:R380 18.16077.52YesYes400
131E:E:F419 E:E:I384 22.69717.54YesYes400
132E:E:F419 E:E:L389 1002.44YesYes400
133E:E:I397 E:E:L389 1008.56YesYes400
134E:E:K370 E:E:Q423 81.78075.42NoNo000
135E:E:K370 E:E:R416 79.51222.48NoNo000
136E:E:R416 F:F:Q209 59.092815.19NoYes005
137F:F:Q209 F:F:S206 31.785510.11YesNo055
138F:F:M208 F:F:S206 29.51554.6YesNo035
139E:E:P373 F:F:M208 20.4366.71YesYes5603
140E:E:P414 E:E:V381 27.23117.07YesYes400
141E:E:F419 E:E:V381 36.30553.93YesYes400
142E:E:L389 E:E:W385 31.772819.36YesYes400
143E:E:F419 E:E:T418 40.851618.16YesYes400
144E:E:L389 E:E:Y404 13.61742.34YesYes400
145E:E:I397 E:E:L399 40.85042.85YesYes400
146E:E:L399 E:E:Y404 13.6178.21YesYes400
147E:E:L389 E:E:T407 13.617410.32YesYes400
148E:E:L399 E:E:T407 13.6174.42YesYes400
149E:E:N410 E:E:T418 31.77562.92NoYes000
150E:E:K406 E:E:N410 27.23632.8YesNo000
151E:E:R416 E:E:Y417 18.152411.32NoNo000
152E:E:Y417 F:F:R269 13.616516.46NoNo009
153E:E:D433 E:E:R437 13.6167.15NoNo000
154E:E:R437 E:E:S434 27.23193.95NoNo000
155E:E:E352 E:E:S353 11.35791.44NoNo000
156E:E:E352 E:E:S357 13.62941.44NoNo000
157F:F:F135 F:F:R118 16.724410.69YesNo746
158F:F:D116 F:F:R118 15.964411.91NoNo086
159F:F:R119 F:F:Y155 13.6845.14NoYes067
160F:F:D126 F:F:G127 29.66845.03YesNo099
161F:F:G127 F:F:V150 28.90791.84NoYes099
162F:F:M145 F:F:V150 19.018610.65YesYes7389
163F:F:M145 F:F:P146 16.73765.03YesNo085
164F:F:K188 F:F:P146 14.45543.35YesNo045
165F:F:N196 F:F:Y197 40.200111.63NoYes1088
166F:F:N196 F:F:S214 39.44195.96NoYes1089
167F:F:H194 F:F:S214 37.92575.58NoYes1099
168F:F:H194 F:F:T218 36.40882.74NoYes1097
169F:F:H234 F:F:T218 69.783819.17NoYes037
170F:F:H234 F:F:S232 66.74994.18NoNo035
171F:F:L229 F:F:S232 63.71593NoNo055
172F:F:L229 F:F:W222 57.647814.81NoYes3559
173F:F:T212 F:F:W222 51.57997.28YesYes3599
174F:F:I210 F:F:T212 36.40963.04NoYes069
175F:F:F203 F:F:I210 24.27313.77NoNo096
176F:F:G215 F:F:Y197 40.20014.35YesYes1088
177F:F:G215 F:F:S214 39.44323.71YesYes1089
178F:F:D216 F:F:S214 39.44277.36YesYes1099
179F:F:D216 F:F:T218 36.408810.12YesYes1097
180F:F:F203 F:F:P157 18.2052.89NoNo096
181F:F:D207 F:F:P157 15.17096.44YesNo086
182F:F:K188 F:F:Y174 11.412514.33YesNo7446
183F:F:A185 F:F:Y174 10.65194NoNo036
184F:F:L241 F:F:S199 16.03676.01NoNo089
185F:F:A213 F:F:S199 15.27981.71NoNo079
186F:F:Q209 F:F:T204 20.55045.67YesNo055
187F:F:L211 F:F:T204 13.74662.95NoNo065
188F:F:F254 F:F:L211 11.478715.83NoNo086
189F:F:R269 F:F:S270 11.34845.27NoNo094
190F:F:A213 F:F:C219 10.73981.81NoNo078
191R:R:I754 R:R:L721 10012.85YesNo079
192R:R:L721 R:R:R757 1009.72NoYes099
193C:C:Y114 R:R:R757 1004.12YesYes279
194C:C:F115 C:C:Y114 54.22279.28YesYes277
195C:C:F115 C:C:F196 56.611136.44YesYes279
196C:C:F196 C:C:W197 58.54158.02YesYes099
197C:C:W197 C:C:Y128 53.08838.68YesYes098
198C:C:E149 C:C:Y128 52.39253.37YesYes1898
199C:C:E149 C:C:L145 84.474810.6YesNo099
200C:C:A150 C:C:L145 84.33441.58NoNo089
201C:C:A150 R:R:P604 83.76913.74NoYes089
202R:R:P604 R:R:V603 82.91593.53YesNo8699
203R:R:S605 R:R:V603 82.79594.85NoNo099
204R:R:A606 R:R:S605 82.65531.71NoNo099
205R:R:A606 R:R:F607 82.51486.93NoNo098
206R:R:F607 R:R:S446 82.37425.28NoYes088
207R:R:K666 R:R:S446 81.2496.12NoYes098
208R:R:K666 R:R:S450 80.82014.59NoNo8399
209R:R:K502 R:R:S450 80.68611.53YesNo099
210R:R:K502 R:R:M613 79.55975.76YesNo097
211R:R:L662 R:R:M613 75.32927.07NoNo087
212R:R:L661 R:R:L662 75.1881.38NoNo088
213R:R:L661 R:R:V657 74.90552.98NoNo087
214R:R:N619 R:R:V657 74.48185.91NoNo097
215R:R:I623 R:R:N619 74.34057.08YesNo059
216R:R:H650 R:R:I623 64.96683.98YesYes095
217R:R:F627 R:R:H650 24.750614.71YesYes099
218R:R:F627 R:R:L646 11.58214.87YesNo098
219R:R:L646 R:R:R631 11.15283.64NoNo089
220R:R:F632 R:R:R631 22.03146.41NoNo099
221R:R:D579 R:R:F632 17.40523.58NoNo099
222R:R:D579 R:R:R485 16.836113.1NoYes099
223R:R:C481 R:R:R485 10.78542.79NoYes099
224R:R:F627 R:R:Y647 12.74155.16YesYes095
225R:R:R631 R:R:Y647 11.167113.38NoYes095
226R:R:H650 R:R:R488 38.57247.9YesYes099
227R:R:E586 R:R:R488 35.69825.82YesYes099
228R:R:E586 R:R:T582 35.64114.23YesNo098
229R:R:F540 R:R:T582 35.49782.59NoNo098
230R:R:F540 S:S:W539 35.35454.01NoNo099
231S:S:F540 S:S:W539 35.06826.01NoNo099
232S:S:F540 S:S:W578 34.35254.01NoYes099
233C:C:T112 C:C:Y114 1002.5YesYes287
234C:C:Q35 R:R:E706 10012.74NoNo088
235C:C:P113 R:R:E706 1003.14NoNo088
236C:C:P113 C:C:T112 1005.25NoYes088
237S:S:W544 S:S:W578 24.43049.37YesYes099
238S:S:R485 S:S:W544 23.7098NoYes099
239S:S:D579 S:S:R485 23.420716.68NoNo099
240S:S:D579 S:S:F632 11.06152.39NoNo099
241S:S:F632 S:S:R631 10.97196.41NoNo099
242S:S:R631 S:S:Y647 10.826911.32NoYes095
243S:S:D579 S:S:T582 12.22327.23NoNo098
244S:S:L489 S:S:T582 12.07784.42NoNo078
245S:S:L489 S:S:R488 11.93272.43NoNo079
246S:S:E586 S:S:R488 11.64282.33YesNo099
247S:S:E586 S:S:S624 10.62294.31YesNo3899
248S:S:E620 S:S:S624 10.53875.75YesNo3899
249C:C:I62 C:C:M34 10.11025.83NoYes078
250C:C:F110 C:C:I41 1005.02NoYes6298
251C:C:F110 C:C:Q35 10010.54NoNo098
252C:C:I41 C:C:W65 1007.05YesYes086
253C:C:F57 C:C:Y108 35.445611.35YesYes058
254C:C:L70 C:C:W65 1002.28NoYes076
255C:C:I72 C:C:L70 1002.85NoNo057
256C:C:E77 C:C:I72 1005.47YesNo095
257B:B:R359 C:C:E77 10012.79YesYes1469
258B:B:I362 C:C:E77 1008.2YesYes1449
259C:C:D96 C:C:P93 34.47293.22NoNo099
260C:C:P93 C:C:Y108 35.02862.78NoYes098
261C:C:D96 C:C:V98 34.42062.92NoYes097
262C:C:V203 C:C:V98 34.2754.81NoYes097
263C:C:V203 C:C:Y148 34.19676.31NoYes1898
264C:C:E149 C:C:Y148 34.265823.57YesYes1898
265C:C:D213 C:C:K215 1006.91NoYes199
266B:B:Y197 C:C:K215 1003.58YesYes189
267B:B:N196 B:B:Y197 89.488811.63NoYes188
268B:B:N196 B:B:S214 91.14575.96NoYes189
269B:B:D216 B:B:S214 1007.36YesYes199
270B:B:D216 B:B:G217 1005.03YesNo197
271B:B:G217 B:B:V240 1001.84NoNo179
272B:B:S256 B:B:V240 1004.85YesNo199
273B:B:S256 B:B:W266 1004.94YesYes199
274B:B:F254 B:B:W266 10011.02NoYes189
275B:B:F254 B:B:L211 10015.83NoNo186
276B:B:L211 B:B:T204 1002.95NoYes165
277B:B:Q209 B:B:T204 1002.83YesYes055
278B:B:Q209 C:C:R416 10015.19YesNo059
279C:C:K370 C:C:R416 1002.48NoNo089
280C:C:K370 C:C:Q423 1005.42NoNo089
281C:C:Q423 C:C:W363 10010.95NoYes096
282C:C:L338 C:C:W363 1003.42NoYes086
283C:C:L338 C:C:R344 1006.07NoNo086
284C:C:P341 C:C:R344 1002.88NoNo056
285C:C:D340 C:C:P341 1008.05YesNo095
286C:C:D340 C:C:R326 1008.34YesYes4099
287C:C:E317 C:C:R326 10015.12NoYes069
288B:B:K117 C:C:E317 1004.05NoNo056
289B:B:D378 B:B:K117 10013.83YesNo085
290B:B:D378 C:C:W314 1003.35YesYes887
291C:C:P305 C:C:W314 10027.02NoYes897
292C:C:N304 C:C:P305 1003.26NoNo099
293C:C:L307 C:C:N304 1006.87NoNo049
294B:B:R98 C:C:L307 1009.72NoNo074
295B:B:A395 B:B:R98 1005.53NoNo087
296B:B:A395 C:C:F296 1002.77NoYes084
297C:C:D294 C:C:F296 1005.97YesYes094
298C:C:D294 C:C:L297 1009.5YesYes094
299B:B:R338 C:C:L297 1003.64YesYes2994
300B:B:L355 B:B:R338 1006.07YesYes2979
301B:B:L355 B:B:V354 1005.96YesNo075
302B:B:V354 B:B:Y319 1002.52NoYes056
303B:B:W352 B:B:Y319 1007.72YesYes096
304B:B:N350 B:B:W352 1004.52YesYes1469
305B:B:N350 B:B:R359 10010.85YesYes1466
306B:B:G215 B:B:Y197 89.48884.35YesYes188
307B:B:G215 B:B:S214 97.77443.71YesYes189
308C:C:R326 C:C:S323 1002.64YesNo094
309C:C:Q325 C:C:S323 1008.66NoNo064
310C:C:D301 C:C:Q325 1005.22NoNo066
311C:C:D301 C:C:F313 1007.17NoYes063
312C:C:F313 C:C:P305 1004.33YesNo839
313B:B:D378 B:B:T380 10013.01YesNo885
314B:B:T380 C:C:W306 1007.28NoYes858
315C:C:N304 C:C:W306 1004.52NoYes098
316B:B:A395 B:B:M95 1004.83NoNo085
317B:B:F93 B:B:M95 10012.44YesNo035
318B:B:F93 C:C:L297 1004.87YesYes034
319B:B:S336 C:C:D294 10011.78NoYes099
320B:B:R338 B:B:S336 1003.95YesNo099
321B:B:I362 B:B:N350 1007.08YesYes1446
322B:B:W149 C:C:D213 10011.17YesNo199
323B:B:E69 B:B:R72 15.54474.65YesNo046
324B:B:R314 B:B:R72 15.96488.53YesNo076
325B:B:A84 B:B:L80 18.69231.58NoYes055
326B:B:A84 B:B:L355 18.90211.58NoYes057
327B:B:R99 C:C:W306 22.74045NoYes878
328B:B:S134 C:C:W306 14.35164.94NoYes868
329B:B:F135 B:B:R99 22.19254.28YesNo847
330C:C:P322 C:C:R326 1004.32YesYes4059
331C:C:P322 C:C:V327 1003.53YesNo059
332C:C:L448 C:C:V327 97.67722.98NoNo089
333C:C:G331 C:C:Y444 46.36132.9NoYes4169
334C:C:L448 C:C:Y444 94.37025.86NoYes4189
335C:C:G331 C:C:Y435 44.70782.9NoYes4169
336C:C:I439 C:C:Y435 44.707814.51NoYes4189
337C:C:I439 C:C:Y444 46.36139.67NoYes4189
338C:C:M334 C:C:M430 38.13784.33YesYes059
339C:C:M430 C:C:W363 1009.31YesYes4296
340C:C:M334 C:C:Y435 76.177916.76YesYes059
341C:C:M334 C:C:S434 1003.07YesNo059
342C:C:F347 C:C:S434 79.48227.93NoNo099
343C:C:F347 C:C:L351 49.67586.09NoNo098
344C:C:F347 C:C:F438 24.839917.15NoNo098
345C:C:L351 C:C:L360 29.80654.15NoNo089
346C:C:F350 C:C:L351 14.90527.31NoNo098
347C:C:F350 C:C:F438 14.9049.65NoNo098
348C:C:E354 C:C:F350 19.87215.83NoNo099
349C:C:E358 C:C:R361 13.26973.49NoNo096
350C:C:E358 C:C:N359 14.928315.77NoNo099
351C:C:I426 C:C:N359 16.58679.91YesNo4289
352C:C:I426 C:C:M430 1005.83YesYes4289
353C:C:R361 C:C:S357 11.6116.59NoNo067
354C:C:L360 C:C:L364 19.87188.3NoNo095
355C:C:F362 C:C:V366 97.76227.87NoNo098
356C:C:Q423 C:C:V366 99.418514.33NoNo098
357C:C:F362 C:C:I426 97.70777.54NoYes098
358C:C:F362 C:C:I397 1007.54NoYes098
359C:C:E367 C:C:L364 14.90457.95NoNo075
360C:C:A365 C:C:D368 11.59113.09NoNo085
361C:C:D368 C:C:R380 13.25665.96NoYes056
362C:C:E383 C:C:R380 13.25119.3NoYes656
363C:C:E383 C:C:E387 16.56442.54NoYes659
364C:C:E387 C:C:F388 26.500822.15YesNo696
365C:C:F388 C:C:I397 33.1266.28NoYes668
366C:C:I384 C:C:R380 13.25537.52YesYes696
367C:C:F419 C:C:I384 16.56537.54YesYes659
368C:C:F419 C:C:L389 79.49752.44YesYes659
369C:C:I397 C:C:L389 1008.56YesYes689
370B:B:S206 C:C:K371 18.23463.06YesNo10554
371B:B:Q209 B:B:S206 26.521311.55YesYes055
372C:C:K371 C:C:R372 16.57793.71NoNo045
373C:C:P373 C:C:R372 14.9212.88NoNo075
374C:C:P414 C:C:V381 23.18697.07YesYes668
375C:C:F419 C:C:V381 29.80853.93YesYes658
376C:C:L389 C:C:W385 23.187819.36YesYes696
377C:C:F419 C:C:T418 29.813918.16YesYes655
378C:C:I397 C:C:L399 29.81262.85YesYes687
379C:C:K406 C:C:N410 19.87772.8YesNo038
380C:C:N410 C:C:T418 23.19072.92NoYes085
381C:C:R416 C:C:Y417 13.250911.32NoNo097
382C:C:R437 C:C:S434 19.87253.95NoNo099
383B:B:I120 B:B:S134 13.80343.1NoNo056
384B:B:N106 B:B:Q125 1005.28NoNo069
385B:B:Q125 B:B:W149 10024.09NoYes099
386B:B:D126 B:B:N106 1006.73NoNo096
387B:B:D116 B:B:R118 11.65164.76NoNo086
388B:B:F135 B:B:R118 12.206310.69YesNo846
389B:B:S123 B:B:V150 19.88738.08NoYes099
390B:B:G127 B:B:V150 1001.84NoYes099
391B:B:D126 B:B:G127 1003.35NoNo099
392B:B:S123 B:B:V129 16.57276.46NoNo097
393B:B:C164 B:B:V129 16.57343.42NoNo077
394B:B:C164 B:B:V150 19.88713.42NoYes10779
395B:B:V129 B:B:V143 26.51694.81NoNo077
396B:B:H141 B:B:M184 13.25857.88NoNo053
397B:B:M184 B:B:V143 19.88776.09NoNo037
398B:B:M145 B:B:V150 82.863310.65YesYes10789
399B:B:M145 B:B:P146 72.92095.03YesNo085
400B:B:K188 B:B:P146 62.97733.35YesNo045
401B:B:F203 B:B:I210 13.26692.51YesNo096
402B:B:I210 B:B:T212 19.90013.04NoYes069
403B:B:T212 B:B:W222 28.19137.28YesYes2499
404B:B:L229 B:B:W222 31.507614.81NoYes2459
405B:B:L229 B:B:S232 34.82413NoNo055
406B:B:H234 B:B:S232 36.48234.18NoNo035
407B:B:H234 B:B:T218 38.140419.17NoYes037
408B:B:G217 B:B:T218 41.42223.64NoYes177
409B:B:K188 B:B:Y174 49.719314.33YesNo10846
410B:B:A185 B:B:Y174 46.40484NoNo036
411B:B:D179 B:B:K180 19.8882.77NoYes033
412B:B:K180 B:B:N183 33.14642.8YesYes6334
413B:B:A185 B:B:N183 43.09034.69NoYes034
414B:B:C273 B:B:M264 43.07064.86NoYes067
415B:B:C273 B:B:W266 44.72699.14NoYes069
416B:B:K262 B:B:M264 39.77854.32NoYes057
417B:B:E278 B:B:K262 38.1426.75NoNo035
418B:B:E278 B:B:K261 36.48386.75NoNo034
419B:B:K261 B:B:T279 34.82563NoYes046
420B:B:R306 B:B:T279 26.533910.35YesYes5486
421B:B:R306 B:B:T304 11.60873.88YesNo086
422E:E:E77 F:F:R359 10012.79YesYes1206
423F:F:N350 F:F:W352 1004.52YesYes1269
424F:F:I362 F:F:N350 1007.08YesYes1246
425C:C:F57 C:C:I41 34.98428.79YesYes6258
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 7EWR
Class C
SubFamily Orphan
Type C orphans
SubType GPR158
Species Homo sapiens
Ligand -
Other Ligand(s) -
Protein Partners B5; RGS7
PDB Resolution 4.7
Date 2021-12-01
D.O.I. 10.1038/s41467-021-27147-1
Net Summary
Imin 2.28
Number of Linked Nodes 2376
Number of Links 2879
Number of Hubs 449
Number of Links mediated by Hubs 1611
Number of Communities 111
Number of Nodes involved in Communities 727
Number of Links involved in Communities 1013
Path Summary
Number Of Nodes in MetaPath 426
Number Of Links MetaPath 425
Number of Shortest Paths 162956683
Length Of Smallest Path 3
Average Path Length 193.595
Length of Longest Path 142
Minimum Path Strength 1.205
Average Path Strength 8.63967
Maximum Path Strength 42.4
Minimum Path Correlation 0.89
Average Path Correlation 1
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 10.3448
Average % Of Corr. Nodes 107.201
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 64.5881
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainF
ProteinG Protein β Sub unit
UniProtO14775
Sequence
>7EWR_Chain_F
DVELHQVAE RVEALGQFV MKTRRTLKG HGNKVLCMD WCKDKRRIV 
SSSQDGKVI VWDSFTTNK EHAVTMPCT WVMACAYAP SGCAIACGG 
LDNKCSVYP LTFDKNENM AAKKKSVAM HTNYLSACS FTNSDMQIL 
TASGDGTCA LWDVESGQL LQSFHGHGA DVLCLDLAP SETGNTFVS 
GGCDKKAMV WDMRSGQCV QAFETHESD INSVRYYPS GDAFASGSD 
DATCRLYDL RADREVAIY SKESIIFGA SSVDFSLSG RLLFAGYND 
YTINVWDVL KGSRVSILF GHENRVSTL RVSPDGTAF CSGSWDHTL 
RVWA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ5T848
Sequence
>7EWR_Chain_R
LAQKLAEEV PMDVASYLY TGDSHQLKR ANCSGRYEL AGLPGKWPA 
LASAHPSLH RALDTLTHA TNFLNVMLQ SNKSREQNL QDDLDWYQA 
LVWSLLEGE PSISRAAIT FSTQVFLQA TREESRILL QDPHLANAT 
LETSHFKWS PPYLECENG SYKPGWLVT LSSAIYGLL VPEFRGVMK 
VDINLQKVD IDQCSSDGW FSGTHKCHL NNSECMPIK GLGFVLGAY 
ECICKAGFY HPAYVCLPC REGCPFCAD DSPCFVQED KYLRLAIIS 
FQALCMLLD FVSMLVVYH FRKAKSIRA SGLILLETI LFGSLLLYF 
PVVILYFEP STFRCILLR WARLLGFAT VYGTVTLKL HRVLKVFLS 
RTAQRIPYM TGGRVMRML AVILLVVFW FLIGWTSSV CQNLEKQIS 
LIGQGKTSD HLIFNMCLI DRWDYMTAV AEFLFLLWG VYLCYAVRT 
VPSAFHEPR YMAVAVHNE LIISAIFHT IRFVLASRL QSDWMLMLY 
FAHTHLTVT VTIGLLLIP KFSAWSEHS LDPEDIRDE LKKLYAQLE 
IYKRKKMIT NNPHLQKKR CSKKGLGRS IMRRITEIP E


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtQ5T848
Sequence
>7EWR_Chain_S
LAQKLAEEV PMDVASYLY TGDSHQLKR ANCSGRYEL AGLPGKWPA 
LASAHPSLH RALDTLTHA TNFLNVMLQ SNKSREQNL QDDLDWYQA 
LVWSLLEGE PSISRAAIT FSTQVFLQA TREESRILL QDPHLANAT 
LETSHFKWS PPYLECENG SYKPGWLVT LSSAIYGLL VPEFRGVMK 
VDINLQKVD IDQCSSDGW FSGTHKCHL NNSECMPIK GLGFVLGAY 
ECICKAGFY HPAYVCLPC REGCPFCAD DSPCFVQED KYLRLAIIS 
FQALCMLLD FVSMLVVYH FRKAKSIRA SGLILLETI LFGSLLLYF 
PVVILYFEP STFRCILLR WARLLGFAT VYGTVTLKL HRVLKVFLS 
RTAQRIPYM TGGRVMRML AVILLVVFW FLIGWTSSV CQNLEKQIS 
LIGQGKTSD HLIFNMCLI DRWDYMTAV AEFLFLLWG VYLCYAVRT 
VPSAFHEPR YMAVAVHNE LIISAIFHT IRFVLASRL QSDWMLMLY 
FAHTHLTVT VTIGLLLIP KFSAWSEHS LDPEDIRDE LKKLYAQLE 
IYKRKKMIT NNPHLQKKR CSKKGLGRS IMRRITEIP ELSSSA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainC
ProteinRGP
UniProtP49802
Sequence
>7EWR_Chain_C
SPNMLVYRK MEDVIARMQ DEKNGIPIR TVKSFLSKI PSVFSGSDI 
VQWLIKNLT IEDPVEALH LGTLMAAHG YFFPISDHV LTLKDDGTF 
YRFQTPYFW PSNCWEPEN TDYAVYLCK RTMQNKARL ELADYEAES 
LARLQRAFA RKWEFIFMQ AEAQAKVDK KRDKIERKI LDSQERAFW 
DVHRPVPGC VNTTEVDIK KSSDELQQQ IKYWQIQLD RHRLKMSKV 
ADSLLSYTE QYLEYDPFL LPPDPSNPW LSDDTTFWE LEASKEPSQ 
QRVKRWGFG MDEALKDPV GREQFLKFL ESEFSSENL RFWLAVEDL 
KKRPIKEVP SRVQEIWQE FLAPGAPSA INLDSKSYD KTTQNVKEP 
GRYTFEDAQ EHIYKLMKS DSYPRFIRS SAYQELLQA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtO14775
Sequence
>7EWR_Chain_B
LKSEAESLK GKLEEERAK LHDVELHQV AERVEALGQ FVMKTRRTL 
KGHGNKVLC MDWCKDKRR IVSSSQDGK VIVWDSFTT NKEHAVTMP 
CTWVMACAY APSGCAIAC GGLDNKCSV YPLTFDKNE NMAAKKKSV 
AMHTNYLSA CSFTNSDMQ ILTASGDGT CALWDVESG QLLQSFHGH 
GADVLCLDL APSETGNTF VSGGCDKKA MVWDMRSGQ CVQAFETHE 
SDINSVRYY PSGDAFASG SDDATCRLY DLRADREVA IYSKESIIF 
GASSVDFSL SGRLLFAGY NDYTINVWD VLKGSRVSI LFGHENRVS 
TLRVSPDGT AFCSGSWDH TLRVWA


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7EWLCOrphanC orphansGPR158Homo sapiens---3.522021-12-0110.1038/s41467-021-27147-1
7EWPCOrphanC orphansGPR158Homo sapiens--B5; RGS74.32021-12-0110.1038/s41467-021-27147-1
7EWRCOrphanC orphansGPR158Homo sapiens--B5; RGS74.72021-12-0110.1038/s41467-021-27147-1
7SHECOrphanC orphansGPR158Homo sapiens-PI; PE-3.42021-12-0110.1126/science.abl4732
7SHFCOrphanC orphansGPR158Homo sapiens-PI; PEB5; RGS73.42021-12-0110.1126/science.abl4732




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7EWR.zip



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