Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:Y32 8.8125435
2R:R:Y33 8.2075437
3R:R:Y63 4.512508
4R:R:Y65 4.82408
5R:R:L69 4.91429
6R:R:V81 3.9275407
7R:R:P100 6.1875404
8R:R:E108 6.7525405
9R:R:F109 10.2025415
10R:R:T119 4.4375428
11R:R:R126 4.8125429
12R:R:Y127 6.13458
13R:R:H132 4.838557
14R:R:Y136 7.4475447
15R:R:S140 4.27448
16R:R:Y163 5.27167614
17R:R:W166 8.40143715
18R:R:W170 7.716512
19R:R:Y174 6.0625416
20R:R:H180 12.5675414
21R:R:V191 5.8725405
22R:R:L202 3.86407
23R:R:T223 1.57406
24R:R:T227 4.065468
25R:R:L230 5.0275428
26R:R:I233 5.7825428
27R:R:W241 6.486518
28R:R:M247 4.35414
29R:R:F282 5.956509
30R:R:Y285 6.548529
31L:L:?1 9.889091110
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:D84 R:R:E88 10.37317.8NoNo043
2R:R:D84 R:R:E108 12.940811.69NoYes045
3L:L:?1 R:R:E108 36.21453.02YesYes005
4L:L:?1 R:R:L275 23.46543.15YesNo006
5R:R:D73 R:R:L69 40.78374.07NoYes099
6R:R:L69 R:R:T119 28.5164.42YesYes298
7R:R:T119 R:R:Y285 22.2443.75YesYes289
8R:R:L284 R:R:Y285 97.51714.69NoYes289
9R:R:I236 R:R:L284 1004.28NoNo068
10R:R:I236 R:R:L240 99.83954.28NoNo068
11R:R:L240 R:R:N277 99.531912.36NoNo089
12R:R:N277 R:R:W241 98.68059.04NoYes198
13R:R:R244 R:R:W241 82.62836NoYes158
14L:L:?1 R:R:R244 81.509427.68YesNo105
15R:R:L69 R:R:N281 20.93346.87YesNo299
16R:R:N281 R:R:Y285 21.896313.96NoYes299
17R:R:D73 R:R:N44 39.02295.39NoNo099
18R:R:F282 R:R:N44 20.93346.04YesNo099
19R:R:I74 R:R:N44 17.19792.83NoNo079
20R:R:I45 R:R:I74 11.5412.94NoNo047
21R:R:R126 R:R:Y285 69.22393.09YesYes299
22R:R:R126 R:R:T123 46.86856.47YesNo099
23R:R:L202 R:R:T123 54.42872.95YesNo079
24R:R:I124 R:R:L202 51.32622.85NoYes067
25R:R:I124 R:R:P121 50.49263.39NoNo067
26R:R:P121 R:R:Y65 36.91886.95NoYes078
27R:R:L122 R:R:Y65 15.70013.52NoYes088
28R:R:L122 R:R:V62 14.54552.98NoNo088
29R:R:V62 R:R:Y63 13.38212.52NoYes088
30R:R:T145 R:R:Y65 19.11022.5NoYes088
31R:R:S61 R:R:T145 13.38214.8NoNo078
32R:R:S140 R:R:S61 12.20974.89YesNo087
33R:R:E108 R:R:I104 24.78055.47YesNo054
34R:R:I104 R:R:P100 22.46241.69NoYes044
35R:R:M96 R:R:P100 14.06866.71NoYes054
36R:R:M96 R:R:P97 12.83381.68NoNo056
37R:R:K102 R:R:P97 10.33751.67NoNo066
38L:L:?1 R:R:W166 27.90983.46YesYes105
39R:R:C156 R:R:W117 12.20972.61NoNo077
40R:R:V120 R:R:W117 14.54557.36NoNo087
41R:R:P121 R:R:V120 16.84575.3NoNo078
42R:R:V191 R:R:W241 19.35994.9YesYes058
43R:R:L230 R:R:R126 28.05246.07YesYes289
44R:R:L202 R:R:Y127 13.08348.21YesYes078
45R:R:I206 R:R:Y127 10.94373.63NoYes088
46R:R:I206 R:R:L230 12.42372.85NoYes088
47R:R:I184 R:R:W166 15.45493.52NoYes045
48L:L:?1 R:R:I169 15.651120.6YesNo104
49R:R:I169 R:R:W170 15.00919.4NoYes142
50R:R:I184 R:R:L252 14.21574.28NoNo045
51R:R:I245 R:R:Y192 11.15774.84NoNo077
52R:R:L230 R:R:T226 24.85182.95YesNo087
53R:R:T226 R:R:T227 22.06121.57NoYes078
54R:R:T223 R:R:T227 17.80861.57YesYes068
55R:R:S222 R:R:T223 10.54251.6NoYes056
56R:R:L275 R:R:V81 15.15622.98NoYes067
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:I80 R:R:V76 3.07 1 No No 6 7 2 2
R:R:I112 R:R:V76 3.07 1 No No 6 7 1 2
R:R:E108 R:R:I80 6.83 0 Yes No 5 6 1 2
R:R:I112 R:R:I80 2.94 1 No No 6 6 1 2
R:R:L275 R:R:V81 2.98 0 No Yes 6 7 1 2
R:R:D84 R:R:E108 11.69 0 No Yes 4 5 2 1
R:R:E108 R:R:I104 5.47 0 Yes No 5 4 1 2
R:R:E105 R:R:W166 13.08 0 No Yes 4 5 2 1
L:L:?1 R:R:E108 3.02 1 Yes Yes 0 5 0 1
R:R:F109 R:R:H113 3.39 1 Yes No 5 6 1 2
R:R:F109 R:R:Y163 6.19 1 Yes Yes 5 4 1 2
R:R:F109 R:R:W166 21.05 1 Yes Yes 5 5 1 1
L:L:?1 R:R:F109 10.18 1 Yes Yes 0 5 0 1
L:L:?1 R:R:I112 5.42 1 Yes No 0 6 0 1
R:R:H113 R:R:Y163 7.62 1 No Yes 6 4 2 2
R:R:W166 R:R:Y163 4.82 1 Yes Yes 5 4 1 2
R:R:L183 R:R:Y163 5.86 1 No Yes 5 4 2 2
R:R:P167 R:R:W166 9.46 1 No Yes 4 5 2 1
R:R:L183 R:R:W166 3.42 1 No Yes 5 5 2 1
R:R:I184 R:R:W166 3.52 0 No Yes 4 5 2 1
L:L:?1 R:R:W166 3.46 1 Yes Yes 0 5 0 1
R:R:P167 R:R:Y174 5.56 1 No Yes 4 6 2 2
R:R:I169 R:R:W170 9.4 1 No Yes 4 2 1 2
R:R:H251 R:R:I169 6.63 1 No No 4 4 1 1
L:L:?1 R:R:I169 20.6 1 Yes No 0 4 0 1
R:R:S267 R:R:W170 3.71 0 No Yes 4 2 2 2
R:R:H251 R:R:Y174 11.98 1 No Yes 4 6 1 2
R:R:C188 R:R:I248 3.27 0 No No 5 5 2 1
R:R:R244 R:R:W241 6 1 No Yes 5 8 1 2
R:R:N271 R:R:R244 12.05 1 No No 6 5 1 1
L:L:?1 R:R:R244 27.68 1 Yes No 0 5 0 1
R:R:I248 R:R:M247 2.92 1 No Yes 5 4 1 1
R:R:M247 R:R:S267 7.67 1 Yes No 4 4 1 2
L:L:?1 R:R:M247 5.37 1 Yes Yes 0 4 0 1
L:L:?1 R:R:I248 8.67 1 Yes No 0 5 0 1
L:L:?1 R:R:H251 9.76 1 Yes No 0 4 0 1
L:L:?1 R:R:N271 11.47 1 Yes No 0 6 0 1
R:R:L275 R:R:T278 4.42 0 No No 6 8 1 2
L:L:?1 R:R:L275 3.15 1 Yes No 0 6 0 1
R:R:M247 R:R:M266 1.44 1 Yes No 4 4 1 2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7VUJ_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.85
Number of Linked Nodes 260
Number of Links 287
Number of Hubs 31
Number of Links mediated by Hubs 122
Number of Communities 6
Number of Nodes involved in Communities 48
Number of Links involved in Communities 65
Path Summary
Number Of Nodes in MetaPath 57
Number Of Links MetaPath 56
Number of Shortest Paths 41338
Length Of Smallest Path 3
Average Path Length 14.2964
Length of Longest Path 32
Minimum Path Strength 1.375
Average Path Strength 6.14194
Maximum Path Strength 24.14
Minimum Path Correlation 0.7
Average Path Correlation 0.967816
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 5.55556
Average % Of Corr. Nodes 71.3912
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 35.4736
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • D1 dopamine receptor binding   • protein binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • molecular function regulator activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • enzyme regulator activity   • cyclase regulator activity   • enzyme activator activity   • cyclase activator activity   • molecular function activator activity   • adenylate cyclase regulator activity   • adenylate cyclase activator activity   • cation binding   • metal ion binding   • developmental process   • multicellular organismal process   • epithelium development   • ectodermal placode morphogenesis   • epidermis development   • molting cycle process   • hair cycle   • animal organ development   • hair follicle placode formation   • tissue development   • ectodermal placode formation   • anatomical structure morphogenesis   • skin development   • skin epidermis development   • hair follicle development
Gene OntologyBiological Process• developmental process   • multicellular organismal process   • epithelium development   • ectodermal placode morphogenesis   • epidermis development   • molting cycle process   • hair cycle   • animal organ development   • hair follicle placode formation   • tissue development   • ectodermal placode formation   • anatomical structure morphogenesis   • skin development   • skin epidermis development   • hair follicle development   • molting cycle   • anatomical structure development   • anatomical structure formation involved in morphogenesis   • ectodermal placode development   • hair cycle process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of smell   • cellular response to stimulus   • cellular response to nitrogen compound   • response to stimulus   • response to endogenous stimulus   • response to peptide hormone   • cellular response to peptide hormone stimulus   • response to oxygen-containing compound   • response to nitrogen compound   • response to glucagon   • cellular response to oxygen-containing compound   • cellular response to glucagon stimulus   • cellular response to endogenous stimulus   • cellular response to chemical stimulus   • response to hormone   • response to chemical   • cellular process   • cellular response to hormone stimulus   • multicellular organism development   • skeletal system development   • bone development   • system development   • regulation of body fluid levels   • wound healing   • homotypic cell-cell adhesion   • cell activation   • hemostasis   • biological regulation   • platelet aggregation   • blood coagulation   • cell adhesion   • cell-cell adhesion   • response to stress   • coagulation   • regulation of biological quality   • response to wounding   • platelet activation   • response to fluid shear stress   • vascular endothelial cell response to laminar fluid shear stress   • response to laminar fluid shear stress   • cellular response to stress   • cellular response to laminar fluid shear stress   • vascular endothelial cell response to fluid shear stress   • cellular response to fluid shear stress   • cognition   • developmental growth   • growth   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • regulation of biological process   • regulation of cellular process   • signaling   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • signal transduction   • homeostatic process   • positive regulation of biological process   • adaptive thermogenesis   • positive regulation of metabolic process   • multicellular organismal-level homeostasis   • regulation of cold-induced thermogenesis   • cold-induced thermogenesis   • temperature homeostasis   • positive regulation of cold-induced thermogenesis   • positive regulation of multicellular organismal process   • metabolic process   • regulation of multicellular organismal process   • regulation of metabolic process   • positive regulation of cellular process   • regulation of localization   • establishment of protein localization   • nitrogen compound transport   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • transport   • hormone secretion   • protein localization to extracellular region   • localization   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • amide transport   • signal release   • intracellular protein localization   • regulation of peptide hormone secretion   • regulation of signaling   • regulation of transport   • secretion   • regulation of hormone levels   • regulation of peptide transport   • regulation of establishment of protein localization   • establishment of protein localization to extracellular region   • export from cell   • cell-cell signaling   • regulation of protein transport   • protein secretion   • establishment of localization   • regulation of protein secretion   • regulation of secretion   • peptide transport   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • regulation of cell communication   • insulin secretion   • adenylate cyclase-activating adrenergic receptor signaling pathway   • adrenergic receptor signaling pathway   • cellular localization   • establishment of localization in cell   • intracellular transport   • regulation of defense response   • regulation of response to external stimulus   • negative regulation of inflammatory response   • negative regulation of biological process   • inflammatory response to antigenic stimulus   • regulation of response to stress   • regulation of immune system process   • negative regulation of inflammatory response to antigenic stimulus   • defense response   • immune response   • negative regulation of response to stimulus   • negative regulation of immune response   • regulation of inflammatory response to antigenic stimulus   • response to external stimulus   • regulation of inflammatory response   • regulation of response to stimulus   • negative regulation of immune system process   • immune system process   • negative regulation of response to external stimulus   • negative regulation of defense response   • regulation of immune response   • inflammatory response   • positive regulation of adenylate cyclase activity   • positive regulation of molecular function   • regulation of molecular function   • positive regulation of cyclase activity   • activation of adenylate cyclase activity   • regulation of adenylate cyclase activity   • regulation of catalytic activity   • positive regulation of catalytic activity   • positive regulation of lyase activity   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • cellular response to monoamine stimulus   • renal system process   • chemical homeostasis   • multicellular organismal-level water homeostasis   • multicellular organismal-level chemical homeostasis   • renal water homeostasis   • cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • intracellular anatomical structure   • cytoplasm   • cytosol   • Golgi apparatus subcompartment   • Golgi apparatus   • organelle subcompartment   • trans-Golgi network membrane   • intracellular membrane-bounded organelle   • endomembrane system   • intracellular organelle   • trans-Golgi network   • organelle membrane   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • xylanase activity   • hydrolase activity, acting on glycosyl bonds   • endo-1,4-beta-xylanase activity   • hydrolase activity, hydrolyzing O-glycosyl compounds   • peptide receptor activity   • molecular transducer activity   • G protein-coupled receptor activity   • G protein-coupled peptide receptor activity   • signaling receptor activity   • transmembrane signaling receptor activity   • neuropeptide receptor activity   • identical protein binding   • carbohydrate metabolic process   • xylan catabolic process   • catabolic process   • carbohydrate catabolic process   • hemicellulose catabolic process   • primary metabolic process   • macromolecule catabolic process   • xylan metabolic process   • polysaccharide metabolic process   • polysaccharide catabolic process   • metabolic process   • macromolecule metabolic process
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeGDP
PDB ResiduesO:O:?1
Environment DetailsOpen EMBL-EBI Page
CodeGDP
NameGuanosine-5'-Diphosphate
SynonymsGuanosine-5'-Diphosphate
Identifier
FormulaC10 H15 N5 O11 P2
Molecular Weight443.201
SMILES
PubChem8977
Formal Charge0
Total Atoms43
Total Chiral Atoms4
Total Bonds45
Total Aromatic Bonds5

Code7ZQ
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
Code7ZQ
Name3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
Synonyms
Identifier
FormulaC17 H17 Cl N2 O2
Molecular Weight316.782
SMILES
PubChem2548547
Formal Charge0
Total Atoms39
Total Chiral Atoms1
Total Bonds40
Total Aromatic Bonds12

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ6DWJ6
Sequence
>7VUJ_nogp_Chain_R
GFVPVVYYS LLLCLGLPA NILTVIILS QLVARRQKS VYNYLLALA 
AADILVLFF IVFVDFLLE DFILNMQMP QVPDKIIEV LEFSSIHTS 
IWITVPLTI DRYIAVCHP LKYHTVSYP ARTRKVIVS VYITCFLTS 
IPYYWWPNI WTEDYISTS VHHVLIWIH CFTVYLVPC SIFFILNSI 
IVYKLRRKS NFRLRGYST GKTTAILFT ITSIFATLW APRIIMILY 
HLYGAPIQN RWLVHIMSD IANMLALLN TAINFFLYC FISKRFRTM 
AAATLKAFF


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
7VUIAOrphanOrphanGPR139Homo sapiensJNJ-63533054GTPchim(Gs-CtGq)/β1/γ23.32021-12-29doi.org/10.1038/s41422-021-00591-w
7VUI (No Gprot) AOrphanOrphanGPR139Homo sapiensJNJ-63533054GTP3.32021-12-29doi.org/10.1038/s41422-021-00591-w
7VUJAOrphanOrphanGPR139Homo sapiensJNJ-63533054GDPchim(Gs-CtGq)/β1/γ23.82021-12-29doi.org/10.1038/s41422-021-00591-w
7VUJ (No Gprot) AOrphanOrphanGPR139Homo sapiensJNJ-63533054GDP3.82021-12-29doi.org/10.1038/s41422-021-00591-w
7VUGAOrphanOrphanGPR139Homo sapiensJNJ-63533054-Gi1/β1/γ23.22021-12-29doi.org/10.1038/s41422-021-00591-w
7VUG (No Gprot) AOrphanOrphanGPR139Homo sapiensJNJ-63533054-3.22021-12-29doi.org/10.1038/s41422-021-00591-w
7VUHAOrphanOrphanGPR139Homo sapiensJNJ-63533054-chim(Gs-CtGq)/β1/γ23.222021-12-29doi.org/10.1038/s41422-021-00591-w
7VUH (No Gprot) AOrphanOrphanGPR139Homo sapiensJNJ-63533054-3.222021-12-29doi.org/10.1038/s41422-021-00591-w




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Download 7VUJ_nogp.zip



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