psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	L:L:L2	6.28	Yes	No	0	0	0
2	L:L:?1	R:R:D106	8.61	Yes	No	1	0	5
3	L:L:?1	R:R:L109	10.04	Yes	No	0	0	8
4	L:L:?1	R:R:F110	17.67	Yes	Yes	1	0	7
5	L:L:?1	R:R:R201	8.81	Yes	Yes	1	0	5
6	L:L:?1	R:R:R205	16.52	Yes	Yes	1	0	6
7	L:L:?1	R:R:W254	6.2	Yes	Yes	0	0	9
8	L:L:?1	R:R:Y257	9.57	Yes	Yes	0	0	7
9	L:L:L2	R:R:F102	6.09	No	Yes	0	0	6
10	L:L:F3	R:R:R205	5.34	No	Yes	0	0	6
11	L:L:F3	R:R:I268	3.77	No	No	0	0	3
12	R:R:I281	R:R:Y22	3.63	No	No	0	2	2
13	R:R:F24	R:R:I28	12.56	No	No	0	2	5
14	R:R:L25	R:R:V285	4.47	No	No	0	2	6
15	R:R:D26	R:R:Y30	20.69	No	No	0	3	5
16	R:R:F33	R:R:T29	3.89	Yes	No	0	7	5
17	R:R:K85	R:R:Y30	13.14	No	No	0	5	5
18	R:R:F33	R:R:M82	3.73	Yes	No	0	7	7
19	R:R:A288	R:R:F33	4.16	No	Yes	0	5	7
20	R:R:F291	R:R:F33	3.22	Yes	Yes	0	7	7
21	R:R:F292	R:R:T36	6.49	No	Yes	7	5	7
22	R:R:C295	R:R:T36	8.45	Yes	Yes	7	8	7
23	R:R:F37	R:R:V41	3.93	No	No	0	7	6
24	R:R:F37	R:R:P79	7.22	No	No	0	7	9
25	R:R:C295	R:R:L39	4.76	Yes	No	0	8	6
26	R:R:T75	R:R:V41	3.17	No	No	0	6	6
27	R:R:F303	R:R:G43	3.01	No	No	0	7	8
28	R:R:F72	R:R:N44	6.04	No	No	0	7	9
29	R:R:N44	R:R:P298	6.52	No	No	0	9	9
30	R:R:L312	R:R:L46	6.92	No	No	0	5	7
31	R:R:A68	R:R:V47	3.39	No	No	0	8	9
32	R:R:V302	R:R:V47	6.41	No	No	0	7	9
33	R:R:F303	R:R:V47	3.93	No	No	0	7	9
34	R:R:I48	R:R:L65	4.28	No	No	0	7	6
35	R:R:A68	R:R:I48	3.25	No	No	0	8	7
36	R:R:I48	R:R:V69	3.07	No	No	0	7	5
37	R:R:F53	R:R:W49	8.02	No	Yes	0	5	4
38	R:R:R54	R:R:W49	14.99	Yes	Yes	8	5	4
39	R:R:A315	R:R:W49	3.89	No	Yes	8	5	4
40	R:R:L316	R:R:W49	4.56	No	Yes	0	6	4
41	R:R:R54	R:R:V50	3.92	Yes	No	0	5	7
42	R:R:M55	R:R:V50	4.56	No	No	0	5	7
43	R:R:A51	R:R:L65	3.15	No	No	0	7	6
44	R:R:F53	R:R:G52	3.01	No	No	0	5	4
45	R:R:R311	R:R:R54	3.2	No	Yes	0	5	5
46	R:R:A315	R:R:R54	4.15	No	Yes	8	5	5
47	R:R:F308	R:R:M55	7.46	Yes	No	0	9	5
48	R:R:M55	R:R:R311	4.96	No	No	0	5	5
49	R:R:H57	R:R:I62	3.98	No	Yes	0	6	6
50	R:R:T58	R:R:T60	3.14	No	No	0	8	7
51	R:R:T58	R:R:T61	9.42	No	No	0	8	7
52	R:R:R137	R:R:V59	17	Yes	No	0	6	7
53	R:R:A142	R:R:V59	5.09	No	No	0	7	7
54	R:R:T60	R:R:Y64	8.74	No	Yes	0	7	8
55	R:R:A142	R:R:I62	3.25	No	Yes	0	7	6
56	R:R:I62	R:R:K143	7.27	Yes	No	0	6	3
57	R:R:I119	R:R:S63	3.1	No	No	0	9	7
58	R:R:R123	R:R:Y64	4.12	Yes	Yes	2	9	8
59	R:R:V302	R:R:Y64	3.79	No	Yes	2	7	8
60	R:R:F308	R:R:Y64	5.16	Yes	Yes	2	9	8
61	R:R:L115	R:R:N66	9.61	No	No	0	8	9
62	R:R:I146	R:R:N66	5.66	No	No	0	7	9
63	R:R:N66	R:R:W150	13.56	No	No	0	9	9
64	R:R:D71	R:R:L67	4.07	Yes	Yes	2	9	9
65	R:R:I116	R:R:L67	4.28	No	Yes	2	8	9
66	R:R:L67	R:R:N297	4.12	Yes	Yes	2	9	9
67	R:R:D71	R:R:S112	5.89	Yes	No	0	9	9
68	R:R:D71	R:R:S294	7.36	Yes	No	0	9	8
69	R:R:D71	R:R:N297	6.73	Yes	Yes	2	9	9
70	R:R:F72	R:R:T75	5.19	No	No	0	7	6
71	R:R:F72	R:R:S76	7.93	No	No	0	7	5
72	R:R:C73	R:R:N108	4.72	No	No	0	7	8
73	R:R:F74	R:R:V105	5.24	Yes	No	0	7	6
74	R:R:F74	R:R:N108	3.62	Yes	No	0	7	8
75	R:R:F291	R:R:F74	17.15	Yes	Yes	0	7	7
76	R:R:F74	R:R:S294	6.61	Yes	No	0	7	8
77	R:R:I104	R:R:T77	3.04	No	No	0	5	7
78	R:R:T77	R:R:V105	3.17	No	No	0	7	6
79	R:R:L78	R:R:P79	3.28	No	No	0	8	9
80	R:R:F80	R:R:F93	6.43	No	Yes	0	6	7
81	R:R:F80	R:R:V101	6.55	No	No	0	6	5
82	R:R:F81	R:R:R84	4.28	Yes	No	1	6	5
83	R:R:F81	R:R:V101	3.93	Yes	No	0	6	5
84	R:R:F102	R:R:F81	6.43	Yes	Yes	1	6	6
85	R:R:F81	R:R:V105	9.18	Yes	No	0	6	6
86	R:R:F291	R:R:F81	3.22	Yes	Yes	0	7	6
87	R:R:F93	R:R:V83	6.55	Yes	No	0	7	4
88	R:R:R84	R:R:W91	8	No	Yes	1	5	9
89	R:R:F102	R:R:R84	7.48	Yes	No	1	6	5
90	R:R:D284	R:R:K85	6.91	No	No	0	5	5
91	R:R:M87	R:R:P92	5.03	No	No	0	4	2
92	R:R:H90	R:R:P92	4.58	No	No	0	4	2
93	R:R:H90	R:R:T173	5.48	No	Yes	0	4	3
94	R:R:F93	R:R:W91	11.02	Yes	Yes	0	7	9
95	R:R:C98	R:R:W91	7.84	No	Yes	1	9	9
96	R:R:C176	R:R:W91	9.14	Yes	Yes	1	9	9
97	R:R:F93	R:R:P92	4.33	Yes	No	0	7	2
98	R:R:F93	R:R:L97	12.18	Yes	No	0	7	6
99	R:R:T165	R:R:W95	8.49	No	No	0	4	3
100	R:R:C98	R:R:T166	5.07	No	No	1	9	5
101	R:R:C176	R:R:C98	5.46	Yes	No	1	9	9
102	R:R:K99	R:R:V164	7.59	No	Yes	0	7	5
103	R:R:F100	R:R:I104	3.77	No	No	0	5	5
104	R:R:F102	R:R:V164	5.24	Yes	Yes	1	6	5
105	R:R:C176	R:R:F102	5.59	Yes	Yes	1	9	6
106	R:R:I161	R:R:T103	6.08	No	No	0	5	6
107	R:R:D106	R:R:F110	9.55	No	Yes	1	5	7
108	R:R:D106	R:R:T157	13.01	No	Yes	0	5	7
109	R:R:I107	R:R:L154	5.71	No	No	0	5	3
110	R:R:I107	R:R:T157	7.6	No	Yes	0	5	7
111	R:R:F291	R:R:L109	6.09	Yes	No	0	7	8
112	R:R:F110	R:R:L156	6.09	Yes	No	0	7	5
113	R:R:P213	R:R:V113	3.53	Yes	No	0	9	8
114	R:R:V113	R:R:W254	6.13	No	Yes	0	8	9
115	R:R:F114	R:R:P149	4.33	No	No	0	6	7
116	R:R:F114	R:R:M152	3.73	No	No	0	6	4
117	R:R:I116	R:R:N297	5.66	No	Yes	2	8	9
118	R:R:I116	R:R:Y301	10.88	No	Yes	2	8	9
119	R:R:L118	R:R:V145	4.47	No	No	0	7	6
120	R:R:L118	R:R:P149	3.28	No	No	0	7	7
121	R:R:I119	R:R:R123	7.52	No	Yes	2	9	9
122	R:R:I119	R:R:Y301	6.04	No	Yes	2	9	9
123	R:R:A120	R:R:V217	5.09	No	No	0	9	8
124	R:R:A120	R:R:S220	3.42	No	Yes	0	9	8
125	R:R:C126	R:R:D122	3.11	No	No	5	8	8
126	R:R:D122	R:R:R137	13.1	No	Yes	5	8	6
127	R:R:R123	R:R:Y221	7.2	Yes	Yes	0	9	8
128	R:R:R123	R:R:Y301	6.17	Yes	Yes	2	9	9
129	R:R:C124	R:R:L128	3.17	No	Yes	9	8	8
130	R:R:C124	R:R:S220	6.89	No	Yes	0	8	8
131	R:R:C124	R:R:L223	3.17	No	Yes	9	8	4
132	R:R:V125	R:R:W132	6.13	No	Yes	0	5	4
133	R:R:C126	R:R:T133	10.14	No	No	5	8	5
134	R:R:C126	R:R:R137	6.96	No	Yes	5	8	6
135	R:R:I224	R:R:V127	7.68	No	No	0	8	8
136	R:R:K227	R:R:V127	4.55	No	No	0	5	8
137	R:R:H129	R:R:L128	3.86	No	Yes	0	7	8
138	R:R:L128	R:R:L223	4.15	Yes	Yes	9	8	4
139	R:R:K227	R:R:L128	7.05	No	Yes	0	5	8
140	R:R:H136	R:R:W132	14.81	No	Yes	0	4	4
141	R:R:L141	R:R:W132	3.42	No	Yes	0	4	4
142	R:R:R137	R:R:T133	10.35	Yes	No	5	6	5
143	R:R:H136	R:R:N135	6.38	No	No	0	4	4
144	R:R:K143	R:R:V139	3.04	No	No	0	3	3
145	R:R:G148	R:R:P149	4.06	No	No	0	2	7
146	R:R:L156	R:R:M152	5.65	No	No	0	5	4
147	R:R:T157	R:R:V160	4.76	Yes	Yes	0	7	4
148	R:R:I161	R:R:T157	3.04	No	Yes	0	5	7
149	R:R:V160	R:R:V164	3.21	Yes	Yes	1	4	5
150	R:R:F178	R:R:V160	5.24	Yes	Yes	1	4	4
151	R:R:R201	R:R:V160	3.92	Yes	Yes	1	5	4
152	R:R:I162	R:R:R163	7.52	No	Yes	0	4	5
153	R:R:N179	R:R:R163	4.82	No	Yes	0	4	5
154	R:R:F180	R:R:R163	8.55	No	Yes	0	5	5
155	R:R:P182	R:R:R163	10.09	No	Yes	0	4	5
156	R:R:F178	R:R:V164	5.24	Yes	Yes	1	4	5
157	R:R:N179	R:R:T165	5.85	No	No	0	4	4
158	R:R:C176	R:R:T166	8.45	Yes	No	1	9	5
159	R:R:R190	R:R:V167	3.92	No	No	0	3	1
160	R:R:P168	R:R:V174	3.53	No	No	0	1	5
161	R:R:F178	R:R:M197	3.73	Yes	No	0	4	2
162	R:R:F178	R:R:R201	10.69	Yes	Yes	1	4	5
163	R:R:F180	R:R:V193	11.8	No	No	0	5	4
164	R:R:F180	R:R:M197	28.61	No	No	0	5	2
165	R:R:R190	R:R:S181	7.91	No	No	0	3	5
166	R:R:P182	R:R:W183	5.4	No	No	0	4	1
167	R:R:R190	R:R:T184	11.64	No	No	0	3	2
168	R:R:E189	R:R:N185	6.57	No	No	0	4	2
169	R:R:D186	R:R:P187	6.44	No	No	0	1	4
170	R:R:D186	R:R:E189	6.5	No	No	0	1	4
171	R:R:R269	R:R:V195	5.23	No	No	0	1	4
172	R:R:I268	R:R:L198	5.71	No	No	0	3	4
173	R:R:I203	R:R:T199	3.04	No	No	0	5	3
174	R:R:T199	R:R:T265	3.14	No	No	0	3	4
175	R:R:R201	R:R:R205	3.2	Yes	Yes	1	5	6
176	R:R:G202	R:R:R205	6	No	Yes	0	5	6
177	R:R:G202	R:R:T265	3.64	No	No	0	5	4
178	R:R:F206	R:R:F210	3.22	No	Yes	4	6	8
179	R:R:F206	R:R:Q258	4.68	No	Yes	4	6	8
180	R:R:F206	R:R:L262	12.18	No	No	0	6	6
181	R:R:G209	R:R:P213	4.06	No	Yes	0	6	9
182	R:R:F210	R:R:M214	14.93	Yes	No	0	8	6
183	R:R:F210	R:R:F251	4.29	Yes	No	4	8	6
184	R:R:F210	R:R:S255	6.61	Yes	No	4	8	6
185	R:R:F210	R:R:Q258	9.37	Yes	Yes	4	8	8
186	R:R:A212	R:R:P213	3.74	No	Yes	0	5	9
187	R:R:M214	R:R:S215	3.07	No	No	0	6	3
188	R:R:L243	R:R:Y221	8.21	Yes	Yes	0	7	8
189	R:R:V246	R:R:Y221	6.31	Yes	Yes	0	8	8
190	R:R:I228	R:R:I234	8.83	No	No	3	8	4
191	R:R:I228	R:R:P239	3.39	No	Yes	3	8	7
192	R:R:L233	R:R:Q231	3.99	No	No	0	2	5
193	R:R:I234	R:R:P239	10.16	No	Yes	3	4	7
194	R:R:K235	R:R:S236	3.06	No	No	0	6	6
195	R:R:R241	R:R:S237	5.27	No	No	0	6	5
196	R:R:R238	R:R:V242	3.92	Yes	No	3	7	8
197	R:R:M304	R:R:R238	3.72	No	Yes	3	7	7
198	R:R:L240	R:R:L243	5.54	No	Yes	6	6	7
199	R:R:M304	R:R:V242	4.56	No	No	3	7	8
200	R:R:V246	R:R:Y301	8.83	Yes	Yes	0	8	9
201	R:R:F250	R:R:W254	9.02	No	Yes	0	9	9
202	R:R:F251	R:R:S255	13.21	No	No	4	6	6
203	R:R:C253	R:R:N293	9.45	No	Yes	0	8	9
204	R:R:Q258	R:R:W254	3.29	Yes	Yes	0	8	9
205	R:R:A290	R:R:W254	7.78	No	Yes	0	8	9
206	R:R:N293	R:R:W254	9.04	Yes	Yes	0	9	9
207	R:R:P256	R:R:S255	3.56	No	No	0	9	6
208	R:R:Q258	R:R:Y257	3.38	Yes	Yes	0	8	7
209	R:R:T286	R:R:Y257	7.49	No	Yes	0	7	7
210	R:R:A290	R:R:Y257	4	No	Yes	0	8	7
211	R:R:V260	R:R:V283	3.21	Yes	No	0	5	5
212	R:R:T286	R:R:V260	9.52	No	Yes	0	7	5
213	R:R:E270	R:R:R267	4.65	No	No	0	1	4
214	R:R:I268	R:R:L271	4.28	No	No	0	3	1
215	R:R:E270	R:R:Y276	7.86	No	No	0	1	1
216	R:R:M275	R:R:Q273	5.44	No	No	0	3	4
217	R:R:M275	R:R:Y276	4.79	No	No	0	3	1
218	R:R:I279	R:R:Y276	7.25	No	No	0	5	1
219	R:R:C295	R:R:F292	5.59	Yes	No	7	8	5
220	R:R:F292	R:R:L296	4.87	No	No	0	5	6
221	R:R:L296	R:R:N293	4.12	No	Yes	0	6	9
222	R:R:N293	R:R:N297	10.9	Yes	Yes	0	9	9
223	R:R:L300	R:R:M299	7.07	No	No	0	8	7
224	R:R:F308	R:R:V302	7.87	Yes	No	2	9	7
225	R:R:Q306	R:R:R309	4.67	No	No	0	5	8
226	R:R:D307	R:R:F308	5.97	No	Yes	0	6	9
227	R:R:L312	R:R:L316	4.15	No	No	0	5	6
228	R:R:R137	R:R:W132	3	Yes	Yes	0	6	4
229	R:R:L240	R:R:S244	3	No	No	6	6	5
230	R:R:L243	R:R:S244	3	Yes	No	6	7	5
231	R:R:L272	R:R:V195	2.98	No	No	0	1	4
232	R:R:L223	R:R:V219	2.98	Yes	No	0	4	5
233	R:R:L300	R:R:V246	2.98	No	Yes	0	8	8
234	R:R:N135	R:R:V131	2.96	No	No	0	4	6
235	R:R:L78	R:R:T36	2.95	No	Yes	0	8	7
236	R:R:L223	R:R:T226	2.95	Yes	No	0	4	4
237	R:R:I146	R:R:I62	2.94	No	Yes	0	7	6
238	R:R:I207	R:R:I208	2.94	No	No	0	5	5
239	R:R:D284	R:R:S287	2.94	No	No	0	5	6
240	R:R:D284	R:R:T29	2.89	No	No	0	5	5
241	R:R:P239	R:R:R238	2.88	Yes	Yes	3	7	7
242	R:R:I281	R:R:L25	2.85	No	No	0	2	2
243	R:R:I208	R:R:L156	2.85	No	No	0	5	5
244	R:R:I279	R:R:L271	2.85	No	No	0	5	1
245	L:L:F3	R:R:A264	2.77	No	No	0	0	4
246	R:R:L115	R:R:L67	2.77	No	Yes	0	8	9
247	R:R:A153	R:R:F110	2.77	No	Yes	0	8	7
248	R:R:L198	R:R:L272	2.77	No	No	0	4	1
249	R:R:A261	R:R:R205	2.77	No	Yes	0	6	6
250	R:R:A247	R:R:Y221	2.67	No	Yes	0	8	8
251	R:R:R267	R:R:V266	2.62	No	No	0	4	5
252	R:R:A70	R:R:W150	2.59	No	No	0	8	9
253	R:R:V217	R:R:Y221	2.52	No	Yes	0	8	8
254	R:R:N185	R:R:W183	2.26	No	No	0	2	1
255	R:R:G88	R:R:G89	2.11	No	No	0	2	3
256	R:R:G169	R:R:P168	2.03	No	No	0	2	1
257	R:R:C295	R:R:G40	1.96	Yes	No	0	8	8
258	R:R:A225	R:R:G222	1.95	No	No	0	5	4
259	R:R:A117	R:R:P213	1.87	No	Yes	0	7	9
260	R:R:G280	R:R:V283	1.84	No	No	0	4	5
261	R:R:G89	R:R:T173	1.82	No	Yes	0	3	3
262	R:R:G172	R:R:T173	1.82	No	Yes	0	5	3
263	R:R:P182	R:R:S181	1.78	No	No	0	4	5
264	R:R:P239	R:R:S236	1.78	Yes	No	0	7	6
265	R:R:P168	R:R:V167	1.77	No	No	0	1	1
266	R:R:G274	R:R:M275	1.75	No	No	0	1	3
267	R:R:G43	R:R:L42	1.71	No	No	0	8	4
268	R:R:G94	R:R:L97	1.71	No	No	0	8	6
269	R:R:A282	R:R:V260	1.7	No	Yes	0	6	5
270	R:R:A175	R:R:T177	1.68	No	No	0	3	4
271	R:R:D307	R:R:G305	1.68	No	No	0	6	8
272	R:R:L158	R:R:P159	1.64	No	No	0	4	8
273	R:R:L289	R:R:P256	1.64	No	No	0	7	9
274	R:R:A218	R:R:M214	1.61	No	No	0	4	6
275	R:R:S140	R:R:T138	1.6	No	No	0	4	6
276	R:R:V242	R:R:V246	1.6	No	Yes	0	8	8
277	R:R:V259	R:R:V260	1.6	No	Yes	0	6	5
278	R:R:T29	R:R:V285	1.59	No	No	0	5	6
279	R:R:T36	R:R:V32	1.59	Yes	No	0	7	5
280	R:R:T36	R:R:V35	1.59	Yes	No	0	7	5
281	R:R:T138	R:R:V139	1.59	No	No	0	6	3
282	R:R:T286	R:R:V285	1.59	No	No	0	7	6
283	R:R:A194	R:R:L272	1.58	No	No	0	4	1
284	R:R:A225	R:R:L240	1.58	No	No	6	5	6
285	R:R:A225	R:R:L243	1.58	No	Yes	6	5	7
286	R:R:A249	R:R:L296	1.58	No	No	0	7	6
287	R:R:A249	R:R:L300	1.58	No	No	0	7	8
288	R:R:T56	R:R:T58	1.57	No	No	0	7	8
289	R:R:T171	R:R:T173	1.57	No	Yes	0	1	3
290	R:R:I207	R:R:S211	1.55	No	No	0	5	5
291	R:R:I216	R:R:S220	1.55	No	Yes	0	6	8
292	R:R:I28	R:R:V32	1.54	No	No	0	5	5
293	R:R:I147	R:R:V151	1.54	No	No	0	3	4
294	R:R:I191	R:R:V195	1.54	No	No	0	2	4
295	R:R:I263	R:R:V259	1.54	No	No	0	5	6
296	R:R:H129	R:R:P130	1.53	No	No	0	7	8
297	R:R:F110	R:R:G111	1.51	Yes	No	0	7	7
298	R:R:L121	R:R:S220	1.5	No	Yes	0	6	8
299	R:R:I204	R:R:I208	1.47	No	No	0	3	5
300	R:R:I228	R:R:L233	1.43	No	No	0	8	2
301	R:R:D26	R:R:I27	1.4	No	No	0	3	6
302	R:R:D186	R:R:K188	1.38	No	No	0	1	4
303	R:R:F245	R:R:M304	1.24	No	No	0	6	7
304	R:R:F251	R:R:L252	1.22	No	No	0	6	6
305	R:R:Q306	R:R:R238	1.17	No	Yes	0	5	7
306	R:R:E278	R:R:Y22	1.12	No	No	0	3	2
307	R:R:R238	R:R:R241	1.07	Yes	No	0	7	6
308	R:R:F96	R:R:W95	1	No	No	0	1	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	10.4625	8	1	0
2	R:R:F33	3.75	4	0	7
3	R:R:T36	4.214	5	7	7
4	R:R:W49	7.865	4	8	4
5	R:R:R54	6.565	4	8	5
6	R:R:I62	4.36	4	0	6
7	R:R:Y64	5.4525	4	2	8
8	R:R:L67	3.81	4	2	9
9	R:R:D71	6.0125	4	2	9
10	R:R:F74	8.155	4	0	7
11	R:R:F81	5.408	5	1	6
12	R:R:W91	9	4	1	9
13	R:R:F93	8.102	5	0	7
14	R:R:F102	6.166	5	1	6
15	R:R:F110	7.518	5	1	7
16	R:R:R123	6.2525	4	2	9
17	R:R:L128	4.5575	4	9	8
18	R:R:W132	6.84	4	0	4
19	R:R:R137	10.082	5	5	6
20	R:R:T157	7.1025	4	0	7
21	R:R:V160	4.2825	4	1	4
22	R:R:R163	7.745	4	0	5
23	R:R:V164	5.32	4	1	5
24	R:R:T173	2.6725	4	0	3
25	R:R:C176	7.16	4	1	9
26	R:R:F178	6.225	4	1	4
27	R:R:R201	6.655	4	1	5
28	R:R:R205	6.766	5	1	6
29	R:R:F210	7.684	5	4	8
30	R:R:P213	3.3	4	0	9
31	R:R:S220	3.34	4	0	8
32	R:R:Y221	5.382	5	0	8
33	R:R:L223	3.3125	4	9	4
34	R:R:R238	2.552	5	3	7
35	R:R:P239	4.5525	4	3	7
36	R:R:L243	4.5825	4	6	7
37	R:R:V246	4.93	4	0	8
38	R:R:W254	6.91	6	0	9
39	R:R:Y257	6.11	4	0	7
40	R:R:Q258	5.18	4	4	8
41	R:R:V260	4.0075	4	0	5
42	R:R:F291	7.42	4	0	7
43	R:R:N293	8.3775	4	0	9
44	R:R:C295	5.19	4	7	8
45	R:R:N297	6.8525	4	2	9
46	R:R:Y301	7.98	4	2	9
47	R:R:F308	6.615	4	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	L:L:L2	25.1496	6.28	Yes	No	0	0	0
2	L:L:L2	R:R:F102	24.4495	6.09	No	Yes	0	0	6
3	L:L:?1	R:R:R205	21.7314	16.52	Yes	Yes	1	0	6
4	L:L:F3	R:R:R205	18.2857	5.34	No	Yes	0	0	6
5	L:L:F3	R:R:I268	16.339	3.77	No	No	0	0	3
6	L:L:?1	R:R:Y257	17.8024	9.57	Yes	Yes	0	0	7
7	R:R:T286	R:R:Y257	27.0084	7.49	No	Yes	0	7	7
8	R:R:T286	R:R:V285	13.3628	1.59	No	No	0	7	6
9	L:L:?1	R:R:W254	71.487	6.2	Yes	Yes	0	0	9
10	R:R:N293	R:R:W254	88.5124	9.04	Yes	Yes	0	9	9
11	R:R:L296	R:R:N293	34.5231	4.12	No	Yes	0	6	9
12	R:R:F292	R:R:L296	20.1115	4.87	No	No	0	5	6
13	R:R:F292	R:R:T36	15.6801	6.49	No	Yes	7	5	7
14	R:R:F291	R:R:F33	12.6517	3.22	Yes	Yes	0	7	7
15	R:R:L78	R:R:T36	10.2768	2.95	No	Yes	0	8	7
16	R:R:N293	R:R:N297	62.2838	10.9	Yes	Yes	0	9	9
17	R:R:I116	R:R:N297	71.9455	5.66	No	Yes	2	8	9
18	R:R:I116	R:R:Y301	100	10.88	No	Yes	2	8	9
19	R:R:R123	R:R:Y301	64.1124	6.17	Yes	Yes	2	9	9
20	R:R:R123	R:R:Y64	48.0561	4.12	Yes	Yes	2	9	8
21	R:R:V302	R:R:Y64	13.2036	3.79	No	Yes	2	7	8
22	R:R:V302	R:R:V47	12.4513	6.41	No	No	0	7	9
23	R:R:F308	R:R:Y64	28.8479	5.16	Yes	Yes	2	9	8
24	R:R:F308	R:R:M55	25.674	7.46	Yes	No	0	9	5
25	R:R:M55	R:R:V50	12.1383	4.56	No	No	0	5	7
26	R:R:R54	R:R:V50	10.8012	3.92	Yes	No	0	5	7
27	R:R:R54	R:R:W49	16.2594	14.99	Yes	Yes	8	5	4
28	R:R:M55	R:R:R311	12.2289	4.96	No	No	0	5	5
29	R:R:R311	R:R:R54	10.8863	3.2	No	Yes	0	5	5
30	R:R:L67	R:R:N297	10.8094	4.12	Yes	Yes	2	9	9
31	R:R:L115	R:R:L67	23.1344	2.77	No	Yes	0	8	9
32	R:R:L115	R:R:N66	22.1816	9.61	No	No	0	8	9
33	R:R:I146	R:R:N66	19.2905	5.66	No	No	0	7	9
34	R:R:I146	R:R:I62	18.3104	2.94	No	Yes	0	7	6
35	R:R:A142	R:R:I62	12.3442	3.25	No	Yes	0	7	6
36	R:R:A142	R:R:V59	11.3283	5.09	No	No	0	7	7
37	R:R:R137	R:R:V59	10.307	17	Yes	No	0	6	7
38	R:R:D71	R:R:N297	23.5682	6.73	Yes	Yes	2	9	9
39	R:R:F291	R:R:F74	29.2268	17.15	Yes	Yes	0	7	7
40	R:R:F74	R:R:S294	50.4146	6.61	Yes	No	0	7	8
41	R:R:F81	R:R:V105	22.3244	9.18	Yes	No	0	6	6
42	R:R:F291	R:R:F81	23.8729	3.22	Yes	Yes	0	7	6
43	R:R:F74	R:R:V105	23.5544	5.24	Yes	No	0	7	6
44	R:R:F81	R:R:V101	20.1279	3.93	Yes	No	0	6	5
45	R:R:F80	R:R:V101	18.1813	6.55	No	No	0	6	5
46	R:R:F102	R:R:R84	10.8149	7.48	Yes	No	1	6	5
47	R:R:R84	R:R:W91	27.9392	8	No	Yes	1	5	9
48	R:R:F93	R:R:W91	35.0118	11.02	Yes	Yes	0	7	9
49	R:R:C176	R:R:F102	13.22	5.59	Yes	Yes	1	9	6
50	R:R:C176	R:R:W91	10.1175	9.14	Yes	Yes	1	9	9
51	R:R:F93	R:R:P92	34.3062	4.33	Yes	No	0	7	2
52	R:R:H90	R:R:P92	25.7619	4.58	No	No	0	4	2
53	R:R:H90	R:R:T173	21.4815	5.48	No	Yes	0	4	3
54	L:L:?1	R:R:R201	22.3931	8.81	Yes	Yes	1	0	5
55	R:R:F178	R:R:R201	21.3662	10.69	Yes	Yes	1	4	5
56	R:R:F178	R:R:M197	23.2469	3.73	Yes	No	0	4	2
57	R:R:F180	R:R:M197	22.3079	28.61	No	No	0	5	2
58	R:R:F180	R:R:R163	20.3833	8.55	No	Yes	0	5	5
59	L:L:?1	R:R:F110	14.019	17.67	Yes	Yes	1	0	7
60	R:R:F110	R:R:L156	11.3585	6.09	Yes	No	0	7	5
61	R:R:A249	R:R:L296	25.8635	1.58	No	No	0	7	6
62	R:R:A249	R:R:L300	25.4654	1.58	No	No	0	7	8
63	R:R:L300	R:R:V246	25.0178	2.98	No	Yes	0	8	8
64	R:R:V246	R:R:Y221	37.9084	6.31	Yes	Yes	0	8	8
65	R:R:V217	R:R:Y221	39.8633	2.52	No	Yes	0	8	8
66	R:R:A120	R:R:V217	37.244	5.09	No	No	0	9	8
67	R:R:V246	R:R:Y301	41.2553	8.83	Yes	Yes	0	8	9
68	R:R:R123	R:R:Y221	27.6262	7.2	Yes	Yes	0	9	8
69	R:R:A120	R:R:S220	34.6192	3.42	No	Yes	0	9	8
70	R:R:C124	R:R:S220	26.7119	6.89	No	Yes	0	8	8
71	R:R:C124	R:R:L128	16.0425	3.17	No	Yes	9	8	8
72	R:R:P182	R:R:R163	14.4693	10.09	No	Yes	0	4	5
73	R:R:Q258	R:R:W254	18.6261	3.29	Yes	Yes	0	8	9
74	R:R:Q258	R:R:Y257	12.8274	3.38	Yes	Yes	0	8	7
75	R:R:F210	R:R:Q258	12.2289	9.37	Yes	Yes	4	8	8
76	R:R:L243	R:R:Y221	13.3189	8.21	Yes	Yes	0	7	8
77	R:R:V242	R:R:V246	26.4593	1.6	No	Yes	0	8	8
78	R:R:R238	R:R:V242	21.1548	3.92	Yes	No	3	7	8
79	R:R:P239	R:R:R238	12.4924	2.88	Yes	Yes	3	7	7
80	R:R:T286	R:R:V260	12.7313	9.52	No	Yes	0	7	5
81	R:R:D71	R:R:L67	28.48	4.07	Yes	Yes	2	9	9
82	R:R:D71	R:R:S294	50.5354	7.36	Yes	No	0	9	8
83	R:R:F80	R:R:F93	16.1715	6.43	No	Yes	0	6	7
84	R:R:F81	R:R:R84	19.145	4.28	Yes	No	1	6	5
85	R:R:I116	R:R:L67	28.826	4.28	No	Yes	2	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D106	8.61	1	Yes	No	0	5	0	1
L:L:?1	R:R:L109	10.04	1	Yes	No	0	8	0	1
L:L:?1	R:R:F110	17.67	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:R201	8.81	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:R205	16.52	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W254	6.2	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:Y257	9.57	1	Yes	Yes	0	7	0	1
L:L:L2	R:R:F102	6.09	0	No	Yes	0	6	0	1
L:L:F3	R:R:R205	5.34	0	No	Yes	0	6	0	1
L:L:F3	R:R:I268	3.77	0	No	No	0	3	0	1
R:R:F81	R:R:R84	4.28	1	Yes	No	6	5	2	2
R:R:F102	R:R:F81	6.43	1	Yes	Yes	6	6	1	2
R:R:F291	R:R:F81	3.22	0	Yes	Yes	7	6	2	2
R:R:F102	R:R:R84	7.48	1	Yes	No	6	5	1	2
R:R:F102	R:R:V164	5.24	1	Yes	Yes	6	5	1	2
R:R:C176	R:R:F102	5.59	1	Yes	Yes	9	6	2	1
R:R:D106	R:R:F110	9.55	1	No	Yes	5	7	1	1
R:R:D106	R:R:T157	13.01	1	No	Yes	5	7	1	2
R:R:F291	R:R:L109	6.09	0	Yes	No	7	8	2	1
R:R:F110	R:R:L156	6.09	1	Yes	No	7	5	1	2
R:R:V113	R:R:W254	6.13	0	No	Yes	8	9	2	1
R:R:T157	R:R:V160	4.76	0	Yes	Yes	7	4	2	2
R:R:V160	R:R:V164	3.21	1	Yes	Yes	4	5	2	2
R:R:F178	R:R:V160	5.24	1	Yes	Yes	4	4	2	2
R:R:R201	R:R:V160	3.92	1	Yes	Yes	5	4	1	2
R:R:F178	R:R:V164	5.24	1	Yes	Yes	4	5	2	2
R:R:F178	R:R:R201	10.69	1	Yes	Yes	4	5	2	1
R:R:I268	R:R:L198	5.71	0	No	No	3	4	1	2
R:R:R201	R:R:R205	3.2	1	Yes	Yes	5	6	1	1
R:R:G202	R:R:R205	6	0	No	Yes	5	6	2	1
R:R:F250	R:R:W254	9.02	0	No	Yes	9	9	2	1
R:R:Q258	R:R:W254	3.29	4	Yes	Yes	8	9	2	1
R:R:A290	R:R:W254	7.78	0	No	Yes	8	9	2	1
R:R:N293	R:R:W254	9.04	0	Yes	Yes	9	9	2	1
R:R:Q258	R:R:Y257	3.38	4	Yes	Yes	8	7	2	1
R:R:T286	R:R:Y257	7.49	0	No	Yes	7	7	2	1
R:R:A290	R:R:Y257	4	0	No	Yes	8	7	2	1
R:R:I268	R:R:L271	4.28	0	No	No	3	1	1	2
L:L:F3	R:R:A264	2.77	0	No	No	0	4	0	1
R:R:A153	R:R:F110	2.77	0	No	Yes	8	7	2	1
R:R:A261	R:R:R205	2.77	0	No	Yes	6	6	2	1
R:R:F110	R:R:G111	1.51	1	Yes	No	7	7	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7WVU_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.01
Number of Linked Nodes	277
Number of Links	308
Number of Hubs	47
Number of Links mediated by Hubs	164
Number of Communities	9
Number of Nodes involved in Communities	53
Number of Links involved in Communities	67

Path Summary
Number Of Nodes in MetaPath	86
Number Of Links MetaPath	85
Number of Shortest Paths	79017
Length Of Smallest Path	3
Average Path Length	14.1601
Length of Longest Path	27
Minimum Path Strength	1.12
Average Path Strength	6.37562
Maximum Path Strength	18.58
Minimum Path Correlation	0.7
Average Path Correlation	0.930085
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	47.2175
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.2744
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	FME
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	FME
Name	N-Formylmethionine
Synonyms	L-N-Formylmethionine N-formyl-L-methionine Formyl-methionine N-Formylmethionine (2S)-2-(formylamino)-4-(methylthio)butanoic acid
Identifier
Formula	C6 H11 N O3 S
Molecular Weight	177.221
SMILES
PubChem	439750
Formal Charge	0
Total Atoms	22
Total Chiral Atoms	1
Total Bonds	21
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21462
Sequence	>7WVU_nogp_Chain_R S A G Y L F L D I I T Y L V F A V T F V L G V L G N G L V I W V A G F R M T H T V T T I S Y L N L A V A D F C F T S T L P F F M V R K A M G G H W P F G W F L C K F V F T I V D I N L F G S V F L I A L I A L D R C V C V L H P V W T Q N H R T V S L A K K V I I G P W V M A L L L T L P V I I R V T T V P G K T G T V A C T F N F S P W T N D P K E R I N V A V A M L T V R G I I R F I I G F S A P M S I V A V S Y G L I A T K I H K Q G L I K S S R P L R V L S F V A A A F F L C W S P Y Q V V A L I A T V R I R E L L Q G M Y K E I G I A V D V T S A L A F F N S C L N P M L Y V F M G Q D F R E R L I H A L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7T6T	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLFII	-	Gi1/β1/γ2	3.2	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7T6T (No Gprot)	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLFII	-		3.2	2022-03-30	doi.org/10.1038/s41467-022-28586-0
	7WVU	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-	Gi1/β1/γ2	3.3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7WVU (No Gprot)	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-		3.3	2022-04-13	doi.org/10.1038/s41467-022-29361-x
	7EUO	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-	Gi1/β1/γ2	2.9	2022-05-25	doi.org/10.1038/s41467-022-32822-y
	7EUO (No Gprot)	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-		2.9	2022-05-25	doi.org/10.1038/s41467-022-32822-y
	7VFX	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMIFL	-	Gi1/β1/γ2	2.8	2022-09-21	doi.org/10.1038/s41467-022-32822-y
	7VFX (No Gprot)	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMIFL	-		2.8	2022-09-21	doi.org/10.1038/s41467-022-32822-y
	9KFT	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLFC	-	Gi1/β1/γ2	3.06	2025-11-12	To be published
	9KFT (No Gprot)	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLFC	-		3.06	2025-11-12	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7WVU_nogp.zip

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