psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F4	R:R:T3	6.49	No	No	0	4	5
2	R:R:L5	R:R:W164	5.69	No	No	0	4	2
3	R:R:I7	R:R:S10	3.1	No	No	0	5	5
4	R:R:F9	R:R:W66	4.01	No	Yes	4	3	4
5	R:R:E70	R:R:F9	9.33	No	No	4	4	3
6	R:R:I13	R:R:W66	4.7	No	Yes	0	4	4
7	R:R:S270	R:R:T16	3.2	No	No	0	5	7
8	R:R:S273	R:R:T16	3.2	No	No	0	8	7
9	R:R:F17	R:R:N21	9.67	Yes	No	3	5	5
10	R:R:F17	R:R:W60	6.01	Yes	No	3	5	1
11	R:R:F17	R:R:V63	10.49	Yes	No	0	5	4
12	R:R:G20	R:R:I19	3.53	No	Yes	5	9	5
13	R:R:I19	R:R:S273	3.1	Yes	No	5	5	8
14	R:R:F277	R:R:I19	3.77	No	Yes	0	5	5
15	R:R:G20	R:R:S273	3.71	No	No	5	9	8
16	R:R:N21	R:R:V56	4.43	No	No	3	5	6
17	R:R:N21	R:R:W60	3.39	No	No	3	5	1
18	R:R:A23	R:R:P276	3.74	No	No	0	7	9
19	R:R:N24	R:R:R55	8.44	No	Yes	0	9	9
20	R:R:N24	R:R:P276	11.4	No	No	0	9	9
21	R:R:F26	R:R:V30	6.55	No	No	6	8	8
22	R:R:F26	R:R:T289	5.19	No	No	6	8	6
23	R:R:I27	R:R:L48	5.71	No	No	0	9	8
24	R:R:I27	R:R:L286	8.56	No	Yes	0	9	9
25	R:R:I33	R:R:L29	5.71	No	No	0	5	6
26	R:R:K285	R:R:V30	3.04	Yes	No	0	8	8
27	R:R:T289	R:R:V30	3.17	No	No	6	6	8
28	R:R:D45	R:R:N31	9.42	Yes	No	0	8	8
29	R:R:N31	R:R:T49	5.85	No	No	0	8	6
30	R:R:K285	R:R:N31	8.39	Yes	No	0	8	8
31	R:R:E34	R:R:R38	13.96	Yes	No	0	6	5
32	R:R:E34	R:R:I41	6.83	Yes	Yes	7	6	6
33	R:R:D45	R:R:E34	3.9	Yes	Yes	7	8	6
34	R:R:E34	R:R:K285	6.75	Yes	Yes	0	6	8
35	R:R:I41	R:R:W35	11.74	Yes	No	0	6	5
36	R:R:F36	R:R:K37	4.96	No	No	0	5	7
37	R:R:D45	R:R:I41	8.4	Yes	Yes	7	8	6
38	R:R:I41	R:R:Q46	4.12	Yes	No	0	6	6
39	R:R:D45	R:R:S42	5.89	Yes	No	0	8	8
40	R:R:F43	R:R:I47	6.28	Yes	No	0	6	9
41	R:R:F105	R:R:F43	13.93	Yes	Yes	0	8	6
42	R:R:F43	R:R:K126	6.2	Yes	No	0	6	7
43	R:R:F43	R:R:V129	6.55	Yes	No	0	6	7
44	R:R:I47	R:R:L102	5.71	No	No	0	9	9
45	R:R:L48	R:R:N283	5.49	No	No	0	8	9
46	R:R:L51	R:R:R55	15.79	No	Yes	0	9	9
47	R:R:L51	R:R:L98	4.15	No	Yes	0	9	7
48	R:R:A99	R:R:L51	3.15	No	No	0	8	9
49	R:R:S54	R:R:S95	4.89	No	No	0	8	8
50	R:R:R55	R:R:S95	6.59	Yes	No	0	9	8
51	R:R:R55	R:R:Y271	7.2	Yes	Yes	1	9	6
52	R:R:H275	R:R:R55	9.03	Yes	Yes	1	9	9
53	R:R:G57	R:R:V56	3.68	No	No	0	1	6
54	R:R:V56	R:R:W60	4.9	No	No	3	6	1
55	R:R:I91	R:R:L58	4.28	No	No	0	5	4
56	R:R:L58	R:R:P272	3.28	No	No	0	4	8
57	R:R:L59	R:R:L62	5.54	No	No	0	7	4
58	R:R:N65	R:R:V61	5.91	No	No	0	4	4
59	R:R:V61	R:R:V87	3.21	No	No	0	4	3
60	R:R:K167	R:R:L62	4.23	No	No	0	4	4
61	R:R:A84	R:R:N65	6.25	No	No	0	3	4
62	R:R:K167	R:R:N65	9.79	No	No	0	4	4
63	R:R:E70	R:R:W66	3.27	No	Yes	4	4	4
64	R:R:L71	R:R:Y67	8.21	No	No	0	4	4
65	R:R:N72	R:R:Y67	10.47	No	No	0	3	4
66	R:R:A68	R:R:F75	5.55	No	No	0	3	2
67	R:R:E70	R:R:I166	4.1	No	No	0	4	3
68	R:R:F75	R:R:V80	13.11	No	No	0	2	2
69	R:R:N76	R:R:R81	6.03	No	Yes	9	3	3
70	R:R:K156	R:R:N76	5.6	Yes	No	9	2	3
71	R:R:S77	R:R:V80	4.85	No	No	0	2	2
72	R:R:I78	R:R:K156	8.72	No	Yes	0	4	2
73	R:R:K156	R:R:R81	18.56	Yes	Yes	9	2	3
74	R:R:E159	R:R:R81	17.45	Yes	Yes	0	5	3
75	R:R:I82	R:R:N86	4.25	No	No	10	2	3
76	R:R:I82	R:R:N148	4.25	No	Yes	10	2	3
77	R:R:I82	R:R:T155	9.12	No	No	0	2	2
78	R:R:M172	R:R:Y85	7.18	No	No	0	3	2
79	R:R:S175	R:R:Y85	6.36	No	No	11	4	2
80	R:R:N176	R:R:Y85	9.3	Yes	No	11	3	2
81	R:R:L144	R:R:N86	8.24	No	No	0	5	3
82	R:R:N148	R:R:N86	12.26	Yes	No	10	3	3
83	R:R:N92	R:R:W88	7.91	No	No	0	8	4
84	R:R:M172	R:R:W88	24.43	No	No	0	3	4
85	R:R:N92	R:R:N96	8.17	No	Yes	1	8	6
86	R:R:N184	R:R:N92	4.09	No	No	1	5	8
87	R:R:H93	R:R:W97	15.87	Yes	Yes	1	5	7
88	R:R:H93	R:R:P136	6.1	Yes	No	1	5	8
89	R:R:H93	R:R:L140	11.57	Yes	No	0	5	5
90	R:R:H93	R:R:L182	5.14	Yes	No	0	5	4
91	R:R:A183	R:R:H93	5.85	No	Yes	0	4	5
92	R:R:F94	R:R:L133	3.65	No	Yes	0	5	8
93	R:R:N184	R:R:N96	5.45	No	Yes	1	5	6
94	R:R:N96	R:R:P187	3.26	Yes	Yes	1	6	8
95	R:R:N96	R:R:Y271	6.98	Yes	Yes	1	6	6
96	R:R:I132	R:R:W97	4.7	No	Yes	0	6	7
97	R:R:P136	R:R:W97	16.21	No	Yes	1	8	7
98	R:R:V186	R:R:W97	3.68	No	Yes	1	6	7
99	R:R:P187	R:R:W97	13.51	Yes	Yes	1	8	7
100	R:R:L98	R:R:S101	4.5	Yes	No	8	7	5
101	R:R:L133	R:R:L98	6.92	Yes	Yes	8	8	7
102	R:R:P187	R:R:T100	5.25	Yes	No	0	8	8
103	R:R:L190	R:R:T100	4.42	No	No	0	5	8
104	R:R:T100	R:R:T191	4.71	No	No	0	8	8
105	R:R:L133	R:R:S101	3	Yes	No	8	8	5
106	R:R:L102	R:R:Y106	9.38	No	No	0	9	9
107	R:R:S103	R:R:T191	6.4	No	No	0	8	8
108	R:R:S103	R:R:S194	3.26	No	Yes	12	8	8
109	R:R:F195	R:R:S103	7.93	Yes	No	12	7	8
110	R:R:I104	R:R:S194	3.1	No	Yes	0	6	8
111	R:R:F105	R:R:K109	13.65	Yes	No	0	8	9
112	R:R:F105	R:R:V125	5.24	Yes	No	0	8	7
113	R:R:F118	R:R:L107	6.09	Yes	No	0	9	8
114	R:R:L107	R:R:S194	3	No	Yes	0	8	8
115	R:R:L107	R:R:L197	4.15	No	No	0	8	7
116	R:R:F118	R:R:L108	3.65	Yes	No	0	9	7
117	R:R:L108	R:R:L121	4.15	No	No	0	7	8
118	R:R:L108	R:R:V125	5.96	No	No	0	7	7
119	R:R:I110	R:R:L198	4.28	No	No	0	9	9
120	R:R:A111	R:R:F113	4.16	No	No	13	8	8
121	R:R:A111	R:R:S201	3.42	No	No	13	8	9
122	R:R:F113	R:R:F118	18.22	No	Yes	0	8	9
123	R:R:F113	R:R:S201	5.28	No	No	13	8	9
124	R:R:I117	R:R:N115	8.5	No	No	0	5	8
125	R:R:F118	R:R:K122	6.2	Yes	No	0	9	9
126	R:R:L121	R:R:V128	8.94	No	No	0	8	6
127	R:R:G135	R:R:P136	4.06	No	No	0	5	8
128	R:R:H143	R:R:I147	6.63	No	Yes	0	6	4
129	R:R:H143	R:R:T178	5.48	No	No	0	6	3
130	R:R:H143	R:R:V179	4.15	No	No	0	6	4
131	R:R:F145	R:R:M149	8.71	No	No	0	3	3
132	R:R:N150	R:R:V146	4.43	No	No	0	1	3
133	R:R:I147	R:R:Q151	4.12	Yes	No	0	4	3
134	R:R:I147	R:R:N176	7.08	Yes	Yes	0	4	3
135	R:R:N150	R:R:Q151	3.96	No	No	0	1	3
136	R:R:Q151	R:R:Y158	9.02	No	No	0	3	1
137	R:R:K156	R:R:W154	3.48	Yes	No	0	2	4
138	R:R:E157	R:R:W154	8.72	No	No	0	1	4
139	R:R:N176	R:R:Y158	8.14	Yes	No	0	3	1
140	R:R:E159	R:R:S170	4.31	Yes	No	0	5	4
141	R:R:A171	R:R:E159	4.53	No	Yes	0	4	5
142	R:R:G160	R:R:N161	3.39	No	No	0	4	9
143	R:R:M162	R:R:S170	6.13	No	No	0	4	4
144	R:R:L174	R:R:M162	4.24	No	No	0	1	4
145	R:R:T163	R:R:W164	10.92	No	No	0	8	2
146	R:R:R169	R:R:W164	4	No	No	0	4	2
147	R:R:K165	R:R:R169	4.95	No	No	0	4	4
148	R:R:F269	R:R:K165	7.44	No	No	0	4	4
149	R:R:K167	R:R:L168	7.05	No	Yes	0	4	3
150	R:R:L168	R:R:M172	4.24	Yes	No	0	3	3
151	R:R:L168	R:R:Y173	12.89	Yes	No	0	3	2
152	R:R:F269	R:R:L168	9.74	No	Yes	0	4	3
153	R:R:E265	R:R:Y173	8.98	No	No	0	3	2
154	R:R:N176	R:R:S175	7.45	Yes	No	11	3	4
155	R:R:N176	R:R:V179	5.91	Yes	No	0	3	4
156	R:R:I181	R:R:L185	5.71	No	Yes	0	5	3
157	R:R:F242	R:R:L185	3.65	Yes	Yes	1	6	3
158	R:R:I245	R:R:L185	5.71	No	Yes	0	4	3
159	R:R:I246	R:R:L185	5.71	No	Yes	1	5	3
160	R:R:P187	R:R:V186	3.53	Yes	No	1	8	6
161	R:R:C238	R:R:F188	4.19	No	Yes	0	7	7
162	R:R:F188	R:R:Y241	5.16	Yes	Yes	1	7	7
163	R:R:F188	R:R:F242	4.29	Yes	Yes	1	7	6
164	R:R:F188	R:R:Y271	11.35	Yes	Yes	1	7	6
165	R:R:F242	R:R:T189	5.19	Yes	No	0	6	4
166	R:R:C238	R:R:T191	5.07	No	No	0	7	8
167	R:R:C238	R:R:L192	3.17	No	No	0	7	7
168	R:R:F195	R:R:S194	3.96	Yes	Yes	12	7	8
169	R:R:F195	R:R:V231	3.93	Yes	No	0	7	7
170	R:R:F195	R:R:F234	7.5	Yes	Yes	0	7	9
171	R:R:L196	R:R:L235	4.15	No	No	0	5	7
172	R:R:L198	R:R:V231	7.45	No	No	0	9	7
173	R:R:I199	R:R:L228	4.28	No	No	0	7	7
174	R:R:I199	R:R:V231	6.14	No	No	0	7	7
175	R:R:I199	R:R:T232	4.56	No	No	0	7	6
176	R:R:H224	R:R:L202	6.43	No	No	0	9	9
177	R:R:L202	R:R:L228	4.15	No	No	0	9	7
178	R:R:C203	R:R:L228	4.76	No	No	0	4	7
179	R:R:H205	R:R:K208	3.93	No	No	2	9	6
180	R:R:H205	R:R:M209	11.82	No	Yes	2	9	9
181	R:R:H205	R:R:H224	10.75	No	No	0	9	9
182	R:R:H224	R:R:L206	5.14	No	No	0	9	6
183	R:R:I225	R:R:L206	5.71	No	No	0	6	6
184	R:R:K207	R:R:L211	7.05	No	No	0	5	5
185	R:R:K208	R:R:M209	4.32	No	Yes	2	6	9
186	R:R:M209	R:R:M221	5.78	Yes	Yes	2	9	6
187	R:R:D218	R:R:K214	16.59	No	No	0	8	5
188	R:R:K214	R:R:S220	6.12	No	No	2	5	8
189	R:R:K214	R:R:M221	7.2	No	Yes	2	5	6
190	R:R:G215	R:R:M221	3.49	No	Yes	0	5	6
191	R:R:D218	R:R:P219	6.44	No	No	0	8	6
192	R:R:M221	R:R:S220	3.07	Yes	No	2	6	8
193	R:R:I225	R:R:Q229	4.12	No	No	0	6	7
194	R:R:F234	R:R:T230	3.89	Yes	No	0	9	8
195	R:R:I278	R:R:S233	4.64	Yes	No	0	8	8
196	R:R:S233	R:R:W281	6.18	No	No	0	8	5
197	R:R:F234	R:R:I278	5.02	Yes	Yes	0	9	8
198	R:R:F234	R:R:G282	3.01	Yes	No	0	9	8
199	R:R:L237	R:R:Y241	11.72	No	Yes	0	7	7
200	R:R:I278	R:R:L237	8.56	Yes	No	0	8	7
201	R:R:Y241	R:R:Y271	13.9	Yes	Yes	1	7	6
202	R:R:T274	R:R:Y241	6.24	No	Yes	0	5	7
203	R:R:H275	R:R:Y241	8.71	Yes	Yes	1	9	7
204	R:R:F242	R:R:I246	8.79	Yes	No	1	6	5
205	R:R:C264	R:R:S244	3.44	No	No	0	3	5
206	R:R:I267	R:R:S244	6.19	No	No	0	5	5
207	R:R:A268	R:R:S244	3.42	No	No	0	5	5
208	R:R:A268	R:R:I245	3.25	No	No	0	5	4
209	R:R:I246	R:R:W250	3.52	No	No	0	5	4
210	R:R:M247	R:R:S251	3.07	No	No	0	5	5
211	R:R:M247	R:R:N257	4.21	No	No	0	5	3
212	R:R:C264	R:R:M247	3.24	No	No	0	3	5
213	R:R:E265	R:R:S248	8.62	No	No	0	3	5
214	R:R:V249	R:R:W250	6.13	No	No	0	3	4
215	R:R:F261	R:R:N257	4.83	No	No	0	1	3
216	R:R:F263	R:R:I267	10.05	No	No	0	5	5
217	R:R:P272	R:R:Y271	5.56	No	Yes	0	8	6
218	R:R:H275	R:R:Y271	4.36	Yes	Yes	1	9	6
219	R:R:H275	R:R:I278	5.3	Yes	Yes	0	9	8
220	R:R:H275	R:R:L279	7.71	Yes	No	0	9	9
221	R:R:I280	R:R:L286	7.14	No	Yes	0	9	9
222	R:R:F290	R:R:I280	3.77	No	No	0	5	9
223	R:R:K287	R:R:W281	9.28	No	No	0	7	5
224	R:R:L286	R:R:N283	6.87	Yes	No	0	9	9
225	R:R:K284	R:R:Q288	13.56	No	No	0	6	6
226	R:R:S292	R:R:T289	3.2	No	No	0	5	6
227	R:R:H296	R:R:W295	5.29	No	No	0	3	3
228	R:R:W295	R:R:Y299	3.86	No	No	0	3	3
229	R:R:V297	R:R:W300	3.68	No	No	0	6	3
230	R:R:N112	R:R:S201	2.98	No	No	0	8	9
231	R:R:L12	R:R:T16	2.95	No	No	0	6	7
232	R:R:L236	R:R:T232	2.95	No	No	0	5	6
233	R:R:I11	R:R:I7	2.94	No	No	0	6	5
234	R:R:I152	R:R:I153	2.94	No	No	0	4	2
235	R:R:Q217	R:R:S216	2.89	No	No	0	6	6
236	R:R:I147	R:R:N148	2.83	Yes	Yes	0	4	3
237	R:R:K285	R:R:L286	2.82	Yes	Yes	0	8	9
238	R:R:K287	R:R:L291	2.82	No	No	0	7	5
239	R:R:A23	R:R:F277	2.77	No	No	0	7	5
240	R:R:A44	R:R:F105	2.77	No	Yes	0	6	8
241	R:R:L102	R:R:L48	2.77	No	No	0	9	8
242	R:R:L133	R:R:L134	2.77	Yes	No	0	8	6
243	R:R:F9	R:R:S10	2.64	No	No	0	3	5
244	R:R:R298	R:R:V301	2.62	No	No	0	5	4
245	R:R:R81	R:R:T155	2.59	Yes	No	0	3	2
246	R:R:F4	R:R:I8	2.51	No	No	0	4	5
247	R:R:F17	R:R:L59	2.44	Yes	No	0	5	7
248	R:R:F195	R:R:L235	2.44	Yes	No	0	7	7
249	R:R:F242	R:R:L243	2.44	Yes	No	0	6	5
250	R:R:L71	R:R:W66	2.28	No	Yes	0	4	4
251	R:R:G215	R:R:S216	1.86	No	No	0	5	6
252	R:R:A28	R:R:A52	1.79	No	No	0	7	8
253	R:R:C264	R:R:V260	1.71	No	No	0	3	3
254	R:R:A28	R:R:V53	1.7	No	No	0	7	5
255	R:R:K258	R:R:P259	1.67	No	No	0	5	1
256	R:R:L5	R:R:P6	1.64	No	No	0	4	3
257	R:R:N72	R:R:P73	1.63	No	No	0	3	4
258	R:R:A52	R:R:I27	1.62	No	No	0	8	9
259	R:R:S127	R:R:V131	1.62	No	No	0	5	4
260	R:R:S292	R:R:V293	1.62	No	No	0	5	6
261	R:R:V14	R:R:V15	1.6	No	No	0	5	5
262	R:R:V14	R:R:V18	1.6	No	No	0	5	5
263	R:R:V293	R:R:V297	1.6	No	No	0	6	6
264	R:R:T83	R:R:V87	1.59	No	No	0	3	3
265	R:R:T180	R:R:V249	1.59	No	No	0	2	3
266	R:R:G213	R:R:H212	1.59	No	No	0	6	6
267	R:R:A266	R:R:L12	1.58	No	No	0	4	6
268	R:R:A50	R:R:L98	1.58	No	Yes	0	6	7
269	R:R:A89	R:R:L140	1.58	No	No	0	5	5
270	R:R:A89	R:R:L144	1.58	No	No	0	5	5
271	R:R:A239	R:R:L192	1.58	No	No	0	6	7
272	R:R:A68	R:R:N72	1.56	No	No	0	3	3
273	R:R:I19	R:R:V15	1.54	Yes	No	0	5	5
274	R:R:I19	R:R:V18	1.54	Yes	No	0	5	5
275	R:R:I166	R:R:T69	1.52	No	No	0	3	4
276	R:R:I193	R:R:T189	1.52	No	No	0	4	4
277	R:R:L29	R:R:S32	1.5	No	No	0	6	4
278	R:R:L64	R:R:V63	1.49	No	No	0	3	4
279	R:R:L137	R:R:V141	1.49	No	No	0	4	3
280	R:R:N257	R:R:S254	1.49	No	No	0	3	1
281	R:R:I33	R:R:K37	1.45	No	No	0	5	7
282	R:R:E79	R:R:S77	1.44	No	No	0	1	2
283	R:R:I8	R:R:L5	1.43	No	No	0	5	4
284	R:R:M149	R:R:N148	1.4	No	Yes	0	3	3
285	R:R:M162	R:R:N161	1.4	No	No	0	4	9
286	R:R:E159	R:R:I166	1.37	Yes	No	0	5	3
287	R:R:K222	R:R:Q217	1.36	No	No	0	6	6
288	R:R:L206	R:R:Q210	1.33	No	No	0	6	6
289	R:R:R124	R:R:S127	1.32	No	No	0	7	5
290	R:R:H212	R:R:M209	1.31	No	Yes	0	6	9
291	R:R:H93	R:R:L137	1.29	Yes	No	0	5	4
292	R:R:F263	R:R:M262	1.24	No	No	0	5	4
293	R:R:I153	R:R:W154	1.17	No	No	0	2	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F17	7.1525	4	3	5
2	R:R:I19	2.696	5	5	5
3	R:R:E34	7.86	4	7	6
4	R:R:I41	7.7725	4	7	6
5	R:R:F43	8.24	4	0	6
6	R:R:D45	6.9025	4	7	8
7	R:R:R55	9.41	5	1	9
8	R:R:W66	3.565	4	4	4
9	R:R:R81	11.1575	4	9	3
10	R:R:H93	7.63667	6	1	5
11	R:R:N96	5.965	4	1	6
12	R:R:W97	10.794	5	1	7
13	R:R:L98	4.2875	4	8	7
14	R:R:F105	8.8975	4	0	8
15	R:R:F118	8.54	4	0	9
16	R:R:L133	4.085	4	8	8
17	R:R:I147	5.165	4	0	4
18	R:R:N148	5.185	4	10	3
19	R:R:K156	9.09	4	9	2
20	R:R:E159	6.915	4	0	5
21	R:R:L168	8.48	4	0	3
22	R:R:N176	7.576	5	11	3
23	R:R:L185	5.195	4	1	3
24	R:R:P187	6.3875	4	1	8
25	R:R:F188	6.2475	4	1	7
26	R:R:S194	3.33	4	12	8
27	R:R:F195	5.152	5	12	7
28	R:R:M209	5.8075	4	2	9
29	R:R:M221	4.885	4	2	6
30	R:R:F234	4.855	4	0	9
31	R:R:Y241	9.146	5	1	7
32	R:R:F242	4.872	5	1	6
33	R:R:Y271	8.225	6	1	6
34	R:R:H275	7.022	5	1	9
35	R:R:I278	5.88	4	0	8
36	R:R:K285	5.25	4	0	8
37	R:R:L286	6.3475	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:R169	R:R:W164	13.8188	4	No	No	0	4	2
2	R:R:K165	R:R:R169	15.7424	4.95	No	No	0	4	4
3	R:R:F269	R:R:K165	17.6467	7.44	No	No	0	4	4
4	R:R:F269	R:R:L168	19.448	9.74	No	Yes	0	4	3
5	R:R:L168	R:R:M172	56.131	4.24	Yes	No	0	3	3
6	R:R:M172	R:R:Y85	51.4411	7.18	No	No	0	3	2
7	R:R:N176	R:R:Y85	48.5396	9.3	Yes	No	11	3	2
8	R:R:I147	R:R:N176	37.0754	7.08	Yes	Yes	0	4	3
9	R:R:I147	R:R:N148	30.018	2.83	Yes	Yes	0	4	3
10	R:R:I82	R:R:N148	26.7756	4.25	No	Yes	10	2	3
11	R:R:I82	R:R:T155	69.2357	9.12	No	No	0	2	2
12	R:R:R81	R:R:T155	67.4086	2.59	Yes	No	0	3	2
13	R:R:E159	R:R:R81	52.3289	17.45	Yes	Yes	0	5	3
14	R:R:E159	R:R:I166	38.4586	1.37	Yes	No	0	5	3
15	R:R:E70	R:R:I166	34.4763	4.1	No	No	0	4	3
16	R:R:E70	R:R:W66	23.7712	3.27	No	Yes	4	4	4
17	R:R:M172	R:R:W88	85.6729	24.43	No	No	0	3	4
18	R:R:N92	R:R:W88	86.4835	7.91	No	No	0	8	4
19	R:R:N92	R:R:N96	86.8245	8.17	No	Yes	1	8	6
20	R:R:N96	R:R:Y271	72.15	6.98	Yes	Yes	1	6	6
21	R:R:R55	R:R:Y271	29.7671	7.2	Yes	Yes	1	9	6
22	R:R:N24	R:R:R55	29.7156	8.44	No	Yes	0	9	9
23	R:R:N24	R:R:P276	27.8242	11.4	No	No	0	9	9
24	R:R:A23	R:R:P276	25.92	3.74	No	No	0	7	9
25	R:R:A23	R:R:F277	24.0028	2.77	No	No	0	7	5
26	R:R:F277	R:R:I19	22.0728	3.77	No	Yes	0	5	5
27	R:R:I19	R:R:S273	10.1904	3.1	Yes	No	5	5	8
28	R:R:F17	R:R:L59	17.6531	2.44	Yes	No	0	5	7
29	R:R:L59	R:R:L62	19.551	5.54	No	No	0	7	4
30	R:R:K167	R:R:L62	21.3073	4.23	No	No	0	4	4
31	R:R:K167	R:R:L168	32.3469	7.05	No	Yes	0	4	3
32	R:R:K285	R:R:V30	22.6711	3.04	Yes	No	0	8	8
33	R:R:K285	R:R:L286	60.1197	2.82	Yes	Yes	0	8	9
34	R:R:I27	R:R:L286	34.65	8.56	No	Yes	0	9	9
35	R:R:I27	R:R:L48	40.3178	5.71	No	No	0	9	8
36	R:R:L102	R:R:L48	77.2452	2.77	No	No	0	9	8
37	R:R:I47	R:R:L102	79.677	5.71	No	No	0	9	9
38	R:R:F43	R:R:I47	80.8736	6.28	Yes	No	0	6	9
39	R:R:F105	R:R:F43	84.2962	13.93	Yes	Yes	0	8	6
40	R:R:F105	R:R:V125	87.6737	5.24	Yes	No	0	8	7
41	R:R:L108	R:R:V125	88.7802	5.96	No	No	0	7	7
42	R:R:F118	R:R:L108	91.9647	3.65	Yes	No	0	9	7
43	R:R:F118	R:R:L107	98.0443	6.09	Yes	No	0	9	8
44	R:R:L107	R:R:S194	100	3	No	Yes	0	8	8
45	R:R:S103	R:R:S194	66.3214	3.26	No	Yes	12	8	8
46	R:R:S103	R:R:T191	94.8662	6.4	No	No	0	8	8
47	R:R:T100	R:R:T191	75.045	4.71	No	No	0	8	8
48	R:R:P187	R:R:T100	75.0579	5.25	Yes	No	0	8	8
49	R:R:N96	R:R:P187	61.3163	3.26	Yes	Yes	1	6	8
50	R:R:L286	R:R:N283	34.3219	6.87	Yes	No	0	9	9
51	R:R:L48	R:R:N283	35.7373	5.49	No	No	0	8	9
52	R:R:T289	R:R:V30	16.2313	3.17	No	No	6	6	8
53	R:R:K285	R:R:N31	12.8731	8.39	Yes	No	0	8	8
54	R:R:E34	R:R:K285	22.5103	6.75	Yes	Yes	0	6	8
55	R:R:L51	R:R:R55	16.2056	15.79	No	Yes	0	9	9
56	R:R:L51	R:R:L98	12.2298	4.15	No	Yes	0	9	7
57	R:R:H275	R:R:Y271	24.0093	4.36	Yes	Yes	1	9	6
58	R:R:L71	R:R:W66	19.7954	2.28	No	Yes	0	4	4
59	R:R:L71	R:R:Y67	17.6467	8.21	No	No	0	4	4
60	R:R:N72	R:R:Y67	15.4851	10.47	No	No	0	3	4
61	R:R:A68	R:R:N72	11.1233	1.56	No	No	0	3	3
62	R:R:K156	R:R:R81	13.272	18.56	Yes	Yes	9	2	3
63	R:R:L144	R:R:N86	49.035	8.24	No	No	0	5	3
64	R:R:P187	R:R:W97	61.0654	13.51	Yes	Yes	1	8	7
65	R:R:H93	R:R:W97	56.3497	15.87	Yes	Yes	1	5	7
66	R:R:H93	R:R:L140	51.5955	11.57	Yes	No	0	5	5
67	R:R:F195	R:R:S103	28.3711	7.93	Yes	No	12	7	8
68	R:R:F195	R:R:F234	41.7524	7.5	Yes	Yes	0	7	9
69	R:R:F234	R:R:I278	43.6053	5.02	Yes	Yes	0	9	8
70	R:R:H275	R:R:I278	45.0785	5.3	Yes	Yes	0	9	8
71	R:R:F195	R:R:V231	55.3139	3.93	Yes	No	0	7	7
72	R:R:E159	R:R:S170	11.1233	4.31	Yes	No	0	5	4
73	R:R:F188	R:R:Y271	31.7808	11.35	Yes	Yes	1	7	6
74	R:R:F188	R:R:F242	46.1207	4.29	Yes	Yes	1	7	6
75	R:R:F242	R:R:L185	30.4876	3.65	Yes	Yes	1	6	3
76	R:R:I245	R:R:L185	26.9107	5.71	No	Yes	0	4	3
77	R:R:C238	R:R:F188	22.3688	4.19	No	Yes	0	7	7
78	R:R:I199	R:R:V231	49.9035	6.14	No	No	0	7	7
79	R:R:I199	R:R:L228	44.2936	4.28	No	No	0	7	7
80	R:R:L202	R:R:L228	40.4851	4.15	No	No	0	9	7
81	R:R:H224	R:R:L202	38.5615	6.43	No	No	0	9	9
82	R:R:H205	R:R:H224	29.0659	10.75	No	No	0	9	9
83	R:R:H205	R:R:M209	25	11.82	No	Yes	2	9	9
84	R:R:M209	R:R:M221	18.9784	5.78	Yes	Yes	2	9	6
85	R:R:C264	R:R:S244	14.7131	3.44	No	No	0	3	5
86	R:R:A268	R:R:S244	22.8963	3.42	No	No	0	5	5
87	R:R:A268	R:R:I245	24.9099	3.25	No	No	0	5	4
88	R:R:C264	R:R:M247	10.5443	3.24	No	No	0	3	5
89	R:R:S292	R:R:T289	13.0404	3.2	No	No	0	5	6
90	R:R:A89	R:R:L144	49.7555	1.58	No	No	0	5	5
91	R:R:I82	R:R:N86	44.2679	4.25	No	No	10	2	3
92	R:R:A89	R:R:L140	50.4761	1.58	No	No	0	5	5
93	R:R:C238	R:R:T191	23.0057	5.07	No	No	0	7	8
94	R:R:F195	R:R:S194	35.5636	3.96	Yes	Yes	12	7	8
95	R:R:H275	R:R:R55	19.8984	9.03	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7XP4_nogp

PDB Summary
PDB	7XP4_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3
Number of Linked Nodes	272
Number of Links	293
Number of Hubs	37
Number of Links mediated by Hubs	131
Number of Communities	13
Number of Nodes involved in Communities	56
Number of Links involved in Communities	64

Path Summary
Number Of Nodes in MetaPath	96
Number Of Links MetaPath	95
Number of Shortest Paths	43847
Length Of Smallest Path	3
Average Path Length	17.2241
Length of Longest Path	44
Minimum Path Strength	1.39
Average Path Strength	6.50811
Maximum Path Strength	18.005
Minimum Path Correlation	0.7
Average Path Correlation	0.942876
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	48.7921
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	38.6654
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • hydrolase activity, acting on glycosyl bonds • glucosidase activity • hydrolase activity, hydrolyzing O-glycosyl compounds • hydrolase activity • beta-glucosidase activity • catalytic activity • cellulase activity • taste receptor activity • molecular transducer activity • bitter taste receptor activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • carbohydrate metabolic process • catabolic process • glucan catabolic process • beta-glucan metabolic process • carbohydrate catabolic process • primary metabolic process • macromolecule catabolic process • polysaccharide metabolic process • glucan metabolic process • beta-glucan catabolic process • polysaccharide catabolic process • metabolic process • cellular process • cellulose catabolic process • macromolecule metabolic process • cellulose metabolic process • multicellular organismal process • system process • nervous system process • response to stimulus • detection of chemical stimulus involved in sensory perception of bitter taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • sensory perception of chemical stimulus • sensory perception • sensory perception of taste • response to chemical • detection of chemical stimulus • sensory perception of bitter taste • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • cell surface • cilium • ciliary membrane • plasma membrane bounded cell projection • cell projection • bounding membrane of organelle • plasma membrane region • organelle membrane • cell projection membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to stimulus • regulation of biological process • regulation of cellular process • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • molecular function regulator activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of smell • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • skeletal system development • bone development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P59540
Sequence	>7XP4_nogp_Chain_R T F L P I I F S I L I V V T F V I G N F A N G F I A L V N S I E W F K R Q K I S F A D Q I L T A L A V S R V G L L W V L V L N W Y A T E L N P A F N S I E V R I T A Y N V W A V I N H F S N W L A T S L S I F Y L L K I A N F S N L I F L H L K R R V K S V V L V I L L G P L L F L V C H L F V I N M N Q I I W T K E Y E G N M T W K I K L R S A M Y L S N T T V T I L A N L V P F T L T L I S F L L L I C S L C K H L K K M Q L H G K G S Q D P S M K V H I K A L Q T V T S F L L L C A I Y F L S I I M S V W S F E S L E N K P V F M F C E A I A F S Y P S T H P F I L I W G N K K L K Q T F L S V L W H V R Y W V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XP4	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP4 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-		3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP5	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.08	2022-10-12	doi.org/10.1126/science.abo1633
	7XP5 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-		3.08	2022-10-12	doi.org/10.1126/science.abo1633
	7XP6	T2	Sensory	Taste2	TAS2R46	Homo sapiens	Strychnine	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP6 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	Strychnine	-		3.01	2022-10-12	doi.org/10.1126/science.abo1633

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7XP4_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.