psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:P6	R:R:T3	3.5	No	No	0	3	5
2	R:R:L5	R:R:W164	3.42	No	Yes	2	4	2
3	R:R:K165	R:R:L5	12.69	Yes	No	2	4	4
4	R:R:F9	R:R:K165	6.2	Yes	Yes	2	3	4
5	R:R:F9	R:R:L168	4.87	Yes	No	0	3	3
6	R:R:F9	R:R:R169	12.83	Yes	Yes	2	3	4
7	R:R:F9	R:R:M172	8.71	Yes	No	0	3	3
8	R:R:S10	R:R:W66	3.71	No	Yes	0	5	4
9	R:R:I13	R:R:W66	10.57	No	Yes	0	4	4
10	R:R:F269	R:R:I13	7.54	No	No	0	4	4
11	R:R:V14	R:R:W66	3.68	No	Yes	0	5	4
12	R:R:S273	R:R:T16	3.2	No	No	0	8	7
13	R:R:F17	R:R:N21	3.62	Yes	No	5	5	5
14	R:R:F17	R:R:W60	6.01	Yes	No	5	5	1
15	R:R:F17	R:R:V63	6.55	Yes	No	0	5	4
16	R:R:F277	R:R:I19	5.02	No	No	0	5	5
17	R:R:N21	R:R:W60	6.78	No	No	5	5	1
18	R:R:A23	R:R:P276	3.74	No	No	0	7	9
19	R:R:A23	R:R:F277	4.16	No	No	0	7	5
20	R:R:N24	R:R:R55	6.03	No	Yes	0	9	9
21	R:R:N24	R:R:P276	11.4	No	No	0	9	9
22	R:R:F26	R:R:T289	3.89	No	No	0	8	6
23	R:R:F26	R:R:F290	4.29	No	No	0	8	5
24	R:R:F26	R:R:V293	3.93	No	No	0	8	6
25	R:R:I27	R:R:N31	4.25	No	Yes	0	9	8
26	R:R:A52	R:R:I27	3.25	No	No	0	8	9
27	R:R:I27	R:R:I280	5.89	No	No	0	9	9
28	R:R:N31	R:R:V30	4.43	Yes	No	0	8	8
29	R:R:T289	R:R:V30	6.35	No	No	0	6	8
30	R:R:D45	R:R:N31	4.04	Yes	Yes	0	8	8
31	R:R:N31	R:R:T49	4.39	Yes	No	0	8	6
32	R:R:L286	R:R:N31	4.12	No	Yes	0	9	8
33	R:R:E34	R:R:R38	12.79	No	No	0	6	5
34	R:R:D45	R:R:E34	6.5	Yes	No	0	8	6
35	R:R:E34	R:R:K285	10.8	No	No	0	6	8
36	R:R:I41	R:R:W35	9.4	No	No	0	6	5
37	R:R:D45	R:R:I41	5.6	Yes	No	0	8	6
38	R:R:I41	R:R:Q46	4.12	No	No	0	6	6
39	R:R:D45	R:R:S42	5.89	Yes	No	0	8	8
40	R:R:F43	R:R:Q46	3.51	Yes	No	0	6	6
41	R:R:F43	R:R:I47	7.54	Yes	No	6	6	9
42	R:R:F105	R:R:F43	12.86	Yes	Yes	6	8	6
43	R:R:F43	R:R:K126	22.33	Yes	No	0	6	7
44	R:R:F43	R:R:V129	3.93	Yes	No	0	6	7
45	R:R:I47	R:R:L102	7.14	No	No	0	9	9
46	R:R:F105	R:R:I47	3.77	Yes	No	6	8	9
47	R:R:L279	R:R:L48	5.54	No	No	0	9	8
48	R:R:A50	R:R:L98	4.73	No	No	0	6	7
49	R:R:L51	R:R:R55	15.79	No	Yes	0	9	9
50	R:R:A99	R:R:L51	3.15	No	No	0	8	9
51	R:R:S54	R:R:S95	6.52	No	No	0	8	8
52	R:R:R55	R:R:S95	7.91	Yes	No	0	9	8
53	R:R:R55	R:R:Y271	15.43	Yes	Yes	3	9	6
54	R:R:P272	R:R:R55	4.32	No	Yes	3	8	9
55	R:R:H275	R:R:R55	11.28	Yes	Yes	3	9	9
56	R:R:V56	R:R:W60	8.58	No	No	0	6	1
57	R:R:L58	R:R:L62	5.54	No	No	0	4	4
58	R:R:L58	R:R:P272	3.28	No	No	0	4	8
59	R:R:V61	R:R:V87	3.21	No	No	0	4	3
60	R:R:L62	R:R:W88	4.56	No	No	0	4	4
61	R:R:F269	R:R:L62	4.87	No	No	0	4	4
62	R:R:A84	R:R:N65	4.69	No	No	0	3	4
63	R:R:E70	R:R:W66	7.63	No	Yes	0	4	4
64	R:R:L71	R:R:W66	6.83	No	Yes	0	4	4
65	R:R:L71	R:R:Y67	8.21	No	No	0	4	4
66	R:R:N72	R:R:Y67	18.61	No	No	0	3	4
67	R:R:F75	R:R:N72	6.04	No	No	0	2	3
68	R:R:S77	R:R:V80	6.46	No	No	0	2	2
69	R:R:I78	R:R:Y158	10.88	No	No	0	4	1
70	R:R:E79	R:R:T83	4.23	No	No	0	1	3
71	R:R:R81	R:R:Y85	9.26	No	No	0	3	2
72	R:R:E157	R:R:R81	10.47	No	No	0	1	3
73	R:R:R81	R:R:Y158	10.29	No	No	0	3	1
74	R:R:I82	R:R:Q151	8.23	No	No	0	2	3
75	R:R:N176	R:R:Y85	8.14	Yes	No	0	3	2
76	R:R:V179	R:R:Y85	3.79	No	No	0	4	2
77	R:R:L144	R:R:N86	5.49	No	No	0	5	3
78	R:R:N92	R:R:W88	9.04	No	No	1	8	4
79	R:R:W88	R:R:Y173	7.72	No	No	1	4	2
80	R:R:A89	R:R:L144	3.15	No	No	0	5	5
81	R:R:N92	R:R:N96	6.81	No	No	0	8	6
82	R:R:N92	R:R:Y173	8.14	No	No	1	8	2
83	R:R:H93	R:R:W97	14.81	Yes	Yes	0	5	7
84	R:R:H93	R:R:L137	6.43	Yes	No	0	5	4
85	R:R:H93	R:R:L140	16.71	Yes	No	0	5	5
86	R:R:H93	R:R:L182	5.14	Yes	No	0	5	4
87	R:R:F94	R:R:L98	8.53	No	No	0	5	7
88	R:R:F94	R:R:L137	4.87	No	No	0	5	4
89	R:R:N184	R:R:N96	4.09	Yes	No	0	5	6
90	R:R:N96	R:R:P187	3.26	No	Yes	0	6	8
91	R:R:T100	R:R:W97	4.85	Yes	Yes	4	8	7
92	R:R:I132	R:R:W97	3.52	No	Yes	0	6	7
93	R:R:P136	R:R:W97	16.21	No	Yes	0	8	7
94	R:R:V186	R:R:W97	3.68	No	Yes	4	6	7
95	R:R:P187	R:R:W97	12.16	Yes	Yes	4	8	7
96	R:R:L133	R:R:L98	6.92	No	No	0	8	7
97	R:R:P187	R:R:T100	5.25	Yes	Yes	4	8	8
98	R:R:T100	R:R:T191	4.71	Yes	No	0	8	8
99	R:R:S101	R:R:V129	3.23	No	No	0	5	7
100	R:R:L133	R:R:S101	9.01	No	No	0	8	5
101	R:R:L102	R:R:Y106	8.21	No	No	0	9	9
102	R:R:S103	R:R:T191	6.4	No	No	0	8	8
103	R:R:S103	R:R:S194	6.52	No	No	0	8	8
104	R:R:F195	R:R:S103	11.89	Yes	No	0	7	8
105	R:R:F105	R:R:K109	7.44	Yes	No	0	8	9
106	R:R:L107	R:R:L108	4.15	No	No	0	8	7
107	R:R:L107	R:R:S194	7.51	No	No	0	8	8
108	R:R:I110	R:R:L198	4.28	No	No	0	9	9
109	R:R:A111	R:R:S201	3.42	No	No	0	8	9
110	R:R:F113	R:R:F118	16.08	No	No	0	8	9
111	R:R:I117	R:R:N115	12.74	No	No	0	5	8
112	R:R:H120	R:R:R124	11.28	No	No	0	5	7
113	R:R:G135	R:R:P136	4.06	No	No	0	5	8
114	R:R:L140	R:R:L144	4.15	No	No	0	5	5
115	R:R:H143	R:R:V146	5.54	No	No	0	6	3
116	R:R:H143	R:R:T178	6.85	No	No	0	6	3
117	R:R:N148	R:R:Q151	3.96	No	No	0	3	3
118	R:R:E157	R:R:Q151	8.92	No	No	0	1	3
119	R:R:K156	R:R:W154	5.8	No	No	0	2	4
120	R:R:E157	R:R:N176	7.89	No	Yes	0	1	3
121	R:R:G160	R:R:N161	3.39	No	No	0	4	9
122	R:R:L168	R:R:M162	4.24	No	No	0	3	4
123	R:R:K167	R:R:T163	6.01	No	No	0	4	8
124	R:R:K165	R:R:W164	3.48	Yes	Yes	2	4	2
125	R:R:I166	R:R:W164	5.87	No	Yes	0	3	2
126	R:R:K258	R:R:W164	8.12	No	Yes	0	5	2
127	R:R:K165	R:R:R169	3.71	Yes	Yes	2	4	4
128	R:R:K165	R:R:M262	4.32	Yes	No	0	4	4
129	R:R:F261	R:R:I166	5.02	Yes	No	0	1	3
130	R:R:E265	R:R:R169	12.79	No	Yes	0	3	4
131	R:R:F269	R:R:R169	16.03	No	Yes	0	4	4
132	R:R:L174	R:R:Y173	9.38	No	No	1	1	2
133	R:R:L174	R:R:T180	11.79	No	No	1	1	2
134	R:R:L174	R:R:N184	5.49	No	Yes	1	1	5
135	R:R:N184	R:R:T180	5.85	Yes	No	1	5	2
136	R:R:I181	R:R:L185	5.71	No	No	0	5	3
137	R:R:I245	R:R:N184	5.66	No	Yes	0	4	5
138	R:R:P187	R:R:V186	3.53	Yes	No	4	8	6
139	R:R:F188	R:R:F242	4.29	No	No	0	7	6
140	R:R:F188	R:R:Y271	12.38	No	Yes	0	7	6
141	R:R:C238	R:R:T191	5.07	No	No	0	7	8
142	R:R:L192	R:R:L235	4.15	No	No	0	7	7
143	R:R:F195	R:R:V231	3.93	Yes	No	0	7	7
144	R:R:F195	R:R:F234	5.36	Yes	Yes	0	7	9
145	R:R:L196	R:R:L235	4.15	No	No	0	5	7
146	R:R:L198	R:R:V231	4.47	No	No	0	9	7
147	R:R:I199	R:R:V231	6.14	No	No	0	7	7
148	R:R:I199	R:R:T232	4.56	No	No	0	7	6
149	R:R:H224	R:R:L202	9	No	No	0	9	9
150	R:R:C203	R:R:L228	3.17	No	No	0	4	7
151	R:R:H205	R:R:H224	9.55	No	No	0	9	9
152	R:R:H224	R:R:L206	7.71	No	No	0	9	6
153	R:R:G215	R:R:Q217	4.93	No	No	0	5	6
154	R:R:D218	R:R:M221	5.54	No	No	0	8	6
155	R:R:I225	R:R:Q229	4.12	No	No	0	6	7
156	R:R:S233	R:R:T230	3.2	No	No	7	8	8
157	R:R:F234	R:R:T230	3.89	Yes	No	7	9	8
158	R:R:F234	R:R:S233	3.96	Yes	No	7	9	8
159	R:R:S233	R:R:W281	6.18	No	No	0	8	5
160	R:R:F234	R:R:I278	10.05	Yes	No	0	9	8
161	R:R:L237	R:R:Y241	10.55	No	Yes	0	7	7
162	R:R:I278	R:R:L237	8.56	No	No	0	8	7
163	R:R:Y241	R:R:Y271	19.86	Yes	Yes	0	7	6
164	R:R:T274	R:R:Y241	7.49	No	Yes	0	5	7
165	R:R:I267	R:R:S244	6.19	No	No	0	5	5
166	R:R:A268	R:R:S244	3.42	No	No	0	5	5
167	R:R:C264	R:R:M247	8.1	No	No	0	3	5
168	R:R:E265	R:R:S248	8.62	No	No	0	3	5
169	R:R:E253	R:R:W250	10.9	No	No	0	2	4
170	R:R:F261	R:R:S251	14.53	Yes	No	0	1	5
171	R:R:E256	R:R:S254	8.62	No	No	0	1	1
172	R:R:F261	R:R:L255	4.87	Yes	No	0	1	3
173	R:R:N257	R:R:V260	5.91	No	No	0	3	3
174	R:R:E265	R:R:F261	11.66	No	Yes	0	3	1
175	R:R:S270	R:R:S273	3.26	No	No	0	5	8
176	R:R:S270	R:R:T274	3.2	No	No	0	5	5
177	R:R:P272	R:R:Y271	5.56	No	Yes	3	8	6
178	R:R:H275	R:R:Y271	5.44	Yes	Yes	3	9	6
179	R:R:H275	R:R:I278	3.98	Yes	No	0	9	8
180	R:R:H275	R:R:L279	11.57	Yes	No	0	9	9
181	R:R:K287	R:R:W281	5.8	No	No	0	7	5
182	R:R:L286	R:R:N283	13.73	No	No	0	9	9
183	R:R:K285	R:R:T289	4.5	No	No	0	8	6
184	R:R:L291	R:R:W295	7.97	No	No	0	5	3
185	R:R:H296	R:R:S292	4.18	No	No	0	3	5
186	R:R:I104	R:R:S194	3.1	No	No	0	6	8
187	R:R:K126	R:R:V125	3.04	No	No	0	7	7
188	R:R:I181	R:R:T180	3.04	No	No	0	5	2
189	R:R:F234	R:R:G282	3.01	Yes	No	0	9	8
190	R:R:N112	R:R:S201	2.98	No	No	0	8	9
191	R:R:L140	R:R:V179	2.98	No	No	0	5	4
192	R:R:N150	R:R:V146	2.96	No	No	0	1	3
193	R:R:L12	R:R:T16	2.95	No	No	0	6	7
194	R:R:L190	R:R:T100	2.95	No	Yes	0	5	8
195	R:R:W295	R:R:Y299	2.89	No	No	0	3	3
196	R:R:E79	R:R:S77	2.87	No	No	0	1	2
197	R:R:I33	R:R:L29	2.85	No	No	0	5	6
198	R:R:I91	R:R:L58	2.85	No	No	0	5	4
199	R:R:I246	R:R:L185	2.85	No	No	0	5	3
200	R:R:I193	R:R:L197	2.85	No	No	0	4	7
201	R:R:I199	R:R:L228	2.85	No	No	0	7	7
202	R:R:I225	R:R:L206	2.85	No	No	0	6	6
203	R:R:M149	R:R:N150	2.8	No	No	0	3	1
204	R:R:A44	R:R:F105	2.77	No	Yes	0	6	8
205	R:R:L107	R:R:L197	2.77	No	No	0	8	7
206	R:R:L198	R:R:L202	2.77	No	No	0	9	9
207	R:R:L202	R:R:L228	2.77	No	No	0	9	7
208	R:R:M221	R:R:Q210	2.72	No	No	0	6	6
209	R:R:E159	R:R:K156	2.7	No	No	0	5	2
210	R:R:F113	R:R:S201	2.64	No	No	0	8	9
211	R:R:F261	R:R:S170	2.64	Yes	No	0	1	4
212	R:R:H205	R:R:M209	2.63	No	No	0	9	9
213	R:R:F17	R:R:V18	2.62	Yes	No	0	5	5
214	R:R:F145	R:R:V141	2.62	No	No	0	3	3
215	R:R:F242	R:R:T189	2.59	No	No	0	6	4
216	R:R:F36	R:R:K37	2.48	No	No	0	5	7
217	R:R:F118	R:R:K122	2.48	No	No	0	9	9
218	R:R:F252	R:R:K167	2.48	No	No	0	2	4
219	R:R:V301	R:R:W300	2.45	No	No	0	4	3
220	R:R:F118	R:R:L108	2.44	No	No	0	9	7
221	R:R:F195	R:R:L235	2.44	Yes	No	0	7	7
222	R:R:I267	R:R:Y241	2.42	No	Yes	0	5	7
223	R:R:N76	R:R:Y158	2.33	No	No	0	3	1
224	R:R:N150	R:R:W154	2.26	No	No	0	1	4
225	R:R:Q288	R:R:W295	2.19	No	No	0	6	3
226	R:R:R123	R:R:R124	2.13	No	No	0	4	7
227	R:R:A28	R:R:G25	1.95	No	No	0	7	7
228	R:R:G20	R:R:S273	1.86	No	No	0	9	8
229	R:R:G57	R:R:V56	1.84	No	No	0	1	6
230	R:R:A28	R:R:A52	1.79	No	No	0	7	8
231	R:R:C264	R:R:S244	1.72	No	No	0	3	5
232	R:R:G20	R:R:L59	1.71	No	No	0	9	7
233	R:R:A171	R:R:S175	1.71	No	No	0	4	4
234	R:R:C264	R:R:V260	1.71	No	No	0	3	3
235	R:R:A28	R:R:V53	1.7	No	No	0	7	5
236	R:R:K258	R:R:P259	1.67	No	No	0	5	1
237	R:R:L5	R:R:P6	1.64	No	No	0	4	3
238	R:R:E159	R:R:G160	1.64	No	No	0	5	4
239	R:R:N72	R:R:P73	1.63	No	No	0	3	4
240	R:R:N76	R:R:P73	1.63	No	No	0	3	4
241	R:R:S127	R:R:V131	1.62	No	No	0	5	4
242	R:R:D218	R:R:P219	1.61	No	No	0	8	6
243	R:R:V14	R:R:V15	1.6	No	No	0	5	5
244	R:R:V293	R:R:V297	1.6	No	No	0	6	6
245	R:R:V297	R:R:V301	1.6	No	No	0	6	4
246	R:R:G213	R:R:H212	1.59	No	No	0	6	6
247	R:R:A266	R:R:L12	1.58	No	No	0	4	6
248	R:R:A239	R:R:L192	1.58	No	No	0	6	7
249	R:R:T177	R:R:T178	1.57	No	No	0	3	3
250	R:R:I7	R:R:S10	1.55	No	No	0	5	5
251	R:R:I11	R:R:S10	1.55	No	No	0	6	5
252	R:R:I91	R:R:V87	1.54	No	No	0	5	3
253	R:R:I104	R:R:V128	1.54	No	No	0	6	6
254	R:R:M209	R:R:S220	1.53	No	No	0	9	8
255	R:R:M221	R:R:S220	1.53	No	No	0	6	8
256	R:R:I78	R:R:T155	1.52	No	No	0	4	2
257	R:R:I181	R:R:T177	1.52	No	No	0	5	3
258	R:R:L121	R:R:V128	1.49	No	No	0	8	6
259	R:R:N176	R:R:S175	1.49	Yes	No	0	3	4
260	R:R:L185	R:R:V249	1.49	No	No	0	3	3
261	R:R:N24	R:R:V56	1.48	No	No	0	9	6
262	R:R:N65	R:R:V61	1.48	No	No	0	4	4
263	R:R:N86	R:R:V90	1.48	No	No	0	3	6
264	R:R:I240	R:R:I267	1.47	No	No	0	6	5
265	R:R:A183	R:R:H93	1.46	No	Yes	0	4	5
266	R:R:N161	R:R:T163	1.46	No	No	0	9	8
267	R:R:F263	R:R:P259	1.44	No	No	0	5	1
268	R:R:I117	R:R:L121	1.43	No	No	0	5	8
269	R:R:I147	R:R:N148	1.42	No	No	0	4	3
270	R:R:I147	R:R:N176	1.42	No	Yes	0	4	3
271	R:R:E70	R:R:T69	1.41	No	No	0	4	4
272	R:R:K287	R:R:L291	1.41	No	No	0	7	5
273	R:R:A68	R:R:F75	1.39	No	No	0	3	2
274	R:R:L116	R:R:L119	1.38	No	No	0	4	7
275	R:R:L134	R:R:L137	1.38	No	No	0	6	4
276	R:R:L116	R:R:N115	1.37	No	No	0	4	8
277	R:R:R124	R:R:S127	1.32	No	No	0	7	5
278	R:R:D218	R:R:Q217	1.31	No	No	0	8	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F9	8.1525	4	2	3
2	R:R:F17	4.7	4	5	5
3	R:R:N31	4.246	5	0	8
4	R:R:F43	10.034	5	6	6
5	R:R:D45	5.5075	4	0	8
6	R:R:R55	10.1267	6	3	9
7	R:R:W66	6.484	5	0	4
8	R:R:H93	8.91	5	0	5
9	R:R:W97	9.205	6	4	7
10	R:R:T100	4.44	4	4	8
11	R:R:F105	6.71	4	6	8
12	R:R:W164	5.2225	4	2	2
13	R:R:K165	6.08	5	2	4
14	R:R:R169	11.34	4	2	4
15	R:R:N176	4.735	4	0	3
16	R:R:N184	5.2725	4	1	5
17	R:R:P187	6.05	4	4	8
18	R:R:F195	5.905	4	0	7
19	R:R:F234	5.254	5	7	9
20	R:R:Y241	10.08	4	0	7
21	R:R:F261	7.744	5	0	1
22	R:R:Y271	11.734	5	3	6
23	R:R:H275	8.0675	4	3	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:K165	R:R:R169	19.9734	3.71	Yes	Yes	2	4	4
2	R:R:F269	R:R:R169	43.2279	16.03	No	Yes	0	4	4
3	R:R:F269	R:R:I13	29.7957	7.54	No	No	0	4	4
4	R:R:I13	R:R:W66	28.1657	10.57	No	Yes	0	4	4
5	R:R:F269	R:R:L62	64.1738	4.87	No	No	0	4	4
6	R:R:L58	R:R:L62	62.6697	5.54	No	No	0	4	4
7	R:R:L58	R:R:P272	62.6277	3.28	No	No	0	4	8
8	R:R:P272	R:R:Y271	29.0541	5.56	No	Yes	3	8	6
9	R:R:Y241	R:R:Y271	13.0334	19.86	Yes	Yes	0	7	6
10	R:R:T274	R:R:Y241	14.1528	7.49	No	Yes	0	5	7
11	R:R:S270	R:R:T274	12.4318	3.2	No	No	0	5	5
12	R:R:S270	R:R:S273	10.6968	3.26	No	No	0	5	8
13	R:R:V56	R:R:W60	11.6762	8.58	No	No	0	6	1
14	R:R:N24	R:R:V56	16.2516	1.48	No	No	0	9	6
15	R:R:N24	R:R:R55	27.4451	6.03	No	Yes	0	9	9
16	R:R:P272	R:R:R55	33.5665	4.32	No	Yes	3	8	9
17	R:R:F26	R:R:T289	21.3236	3.89	No	No	0	8	6
18	R:R:T289	R:R:V30	12.5997	6.35	No	No	0	6	8
19	R:R:N31	R:R:V30	14.3767	4.43	Yes	No	0	8	8
20	R:R:D45	R:R:N31	31.4468	4.04	Yes	Yes	0	8	8
21	R:R:D45	R:R:I41	51.5391	5.6	Yes	No	0	8	6
22	R:R:I41	R:R:Q46	54.5614	4.12	No	No	0	6	6
23	R:R:F43	R:R:Q46	56.0515	3.51	Yes	No	0	6	6
24	R:R:F43	R:R:V129	68.7561	3.93	Yes	No	0	6	7
25	R:R:S101	R:R:V129	70.1483	3.23	No	No	0	5	7
26	R:R:L133	R:R:S101	71.4845	9.01	No	No	0	8	5
27	R:R:L133	R:R:L98	72.8068	6.92	No	No	0	8	7
28	R:R:F94	R:R:L98	75.4093	8.53	No	No	0	5	7
29	R:R:F94	R:R:L137	76.6895	4.87	No	No	0	5	4
30	R:R:H93	R:R:L137	79.2081	6.43	Yes	No	0	5	4
31	R:R:H93	R:R:W97	100	14.81	Yes	Yes	0	5	7
32	R:R:P187	R:R:W97	45.5856	12.16	Yes	Yes	4	8	7
33	R:R:N96	R:R:P187	62.9075	3.26	No	Yes	0	6	8
34	R:R:N92	R:R:N96	42.3324	6.81	No	No	0	8	6
35	R:R:N92	R:R:W88	40.9962	9.04	No	No	1	8	4
36	R:R:L62	R:R:W88	55.9396	4.56	No	No	0	4	4
37	R:R:K285	R:R:T289	12.3269	4.5	No	No	0	8	6
38	R:R:E34	R:R:K285	13.9079	10.8	No	No	0	6	8
39	R:R:D45	R:R:E34	17.4549	6.5	Yes	No	0	8	6
40	R:R:F26	R:R:V293	14.1878	3.93	No	No	0	8	6
41	R:R:I27	R:R:N31	11.1585	4.25	No	Yes	0	9	8
42	R:R:H275	R:R:R55	31.1879	11.28	Yes	Yes	3	9	9
43	R:R:H275	R:R:Y271	18.7841	5.44	Yes	Yes	3	9	6
44	R:R:I91	R:R:L58	10.9347	2.85	No	No	0	5	4
45	R:R:L71	R:R:W66	14.9573	6.83	No	Yes	0	4	4
46	R:R:L71	R:R:Y67	13.6491	8.21	No	No	0	4	4
47	R:R:N72	R:R:Y67	12.7256	18.61	No	No	0	3	4
48	R:R:N76	R:R:Y158	12.047	2.33	No	No	0	3	1
49	R:R:N76	R:R:P73	11.5643	1.63	No	No	0	3	4
50	R:R:N72	R:R:P73	11.5293	1.63	No	No	0	3	4
51	R:R:R81	R:R:Y158	13.6631	10.29	No	No	0	3	1
52	R:R:R81	R:R:Y85	16.3705	9.26	No	No	0	3	2
53	R:R:H93	R:R:L140	38.3378	16.71	Yes	No	0	5	5
54	R:R:L140	R:R:V179	30.7821	2.98	No	No	0	5	4
55	R:R:V179	R:R:Y85	29.278	3.79	No	No	0	4	2
56	R:R:N176	R:R:Y85	14.0618	8.14	Yes	No	0	3	2
57	R:R:W88	R:R:Y173	15.2022	7.72	No	No	1	4	2
58	R:R:N184	R:R:N96	23.2405	4.09	Yes	No	0	5	6
59	R:R:L174	R:R:Y173	14.7055	9.38	No	No	1	1	2
60	R:R:P187	R:R:T100	17.5318	5.25	Yes	Yes	4	8	8
61	R:R:T100	R:R:T191	74.2899	4.71	Yes	No	0	8	8
62	R:R:S103	R:R:T191	73.5064	6.4	No	No	0	8	8
63	R:R:S103	R:R:S194	30.4463	6.52	No	No	0	8	8
64	R:R:F195	R:R:F234	67.308	5.36	Yes	Yes	0	7	9
65	R:R:F234	R:R:I278	66.1886	10.05	Yes	No	0	9	8
66	R:R:H275	R:R:I278	48.9086	3.98	Yes	No	0	9	8
67	R:R:L107	R:R:S194	17.4759	7.51	No	No	0	8	8
68	R:R:L107	R:R:L108	12.2919	4.15	No	No	0	8	7
69	R:R:L198	R:R:V231	31.4887	4.47	No	No	0	9	7
70	R:R:F195	R:R:V231	41.2831	3.93	Yes	No	0	7	7
71	R:R:F118	R:R:L108	10.5289	2.44	No	No	0	9	7
72	R:R:I104	R:R:V128	10.5359	1.54	No	No	0	6	6
73	R:R:I104	R:R:S194	12.2989	3.1	No	No	0	6	8
74	R:R:H143	R:R:T178	20.8619	6.85	No	No	0	6	3
75	R:R:T177	R:R:T178	22.5199	1.57	No	No	0	3	3
76	R:R:I181	R:R:T177	24.164	1.52	No	No	0	5	3
77	R:R:I181	R:R:T180	30.6003	3.04	No	No	0	5	2
78	R:R:L174	R:R:T180	12.8725	11.79	No	No	1	1	2
79	R:R:H143	R:R:V146	19.1899	5.54	No	No	0	6	3
80	R:R:K156	R:R:W154	12.3618	5.8	No	No	0	2	4
81	R:R:N150	R:R:W154	14.0898	2.26	No	No	0	1	4
82	R:R:N150	R:R:V146	17.5038	2.96	No	No	0	1	3
83	R:R:E159	R:R:K156	10.6198	2.7	No	No	0	5	2
84	R:R:E265	R:R:R169	14.2018	12.79	No	Yes	0	3	4
85	R:R:H224	R:R:L202	26.1928	9	No	No	0	9	9
86	R:R:L198	R:R:L202	27.8089	2.77	No	No	0	9	9
87	R:R:H205	R:R:H224	18.6092	9.55	No	No	0	9	9
88	R:R:M221	R:R:S220	12.5367	1.53	No	No	0	6	8
89	R:R:M209	R:R:S220	14.5725	1.53	No	No	0	9	8
90	R:R:H205	R:R:M209	16.6084	2.63	No	No	0	9	9
91	R:R:F234	R:R:S233	14.5236	3.96	Yes	No	7	9	8
92	R:R:S233	R:R:W281	12.5157	6.18	No	No	0	8	5
93	R:R:L237	R:R:Y241	17.315	10.55	No	Yes	0	7	7
94	R:R:I267	R:R:Y241	14.1528	2.42	No	Yes	0	5	7
95	R:R:I267	R:R:S244	10.6968	6.19	No	No	0	5	5
96	R:R:K287	R:R:W281	10.5569	5.8	No	No	0	7	5
97	R:R:V293	R:R:V297	10.8647	1.6	No	No	0	6	6
98	R:R:K165	R:R:W164	10.2071	3.48	Yes	Yes	2	4	2
99	R:R:E265	R:R:F261	10.1861	11.66	No	Yes	0	3	1
100	R:R:T100	R:R:W97	57.5206	4.85	Yes	Yes	4	8	7
101	R:R:F195	R:R:S103	65.8528	11.89	Yes	No	0	7	8
102	R:R:I278	R:R:L237	17.6787	8.56	No	No	0	8	7
103	R:R:N184	R:R:T180	19.2948	5.85	Yes	No	1	5	2

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 7XP5_nogp

PDB Summary
PDB	7XP5_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.15
Number of Linked Nodes	268
Number of Links	278
Number of Hubs	23
Number of Links mediated by Hubs	89
Number of Communities	7
Number of Nodes involved in Communities	28
Number of Links involved in Communities	32

Path Summary
Number Of Nodes in MetaPath	104
Number Of Links MetaPath	103
Number of Shortest Paths	36457
Length Of Smallest Path	3
Average Path Length	15.2915
Length of Longest Path	38
Minimum Path Strength	1.375
Average Path Strength	6.38961
Maximum Path Strength	17.645
Minimum Path Correlation	0.7
Average Path Correlation	0.935629
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	50.0518
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	26.8539
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P59540
Sequence	>7XP5_nogp_Chain_R T F L P I I F S I L I V V T F V I G N F A N G F I A L V N S I E W F K R Q K I S F A D Q I L T A L A V S R V G L L W V L V L N W Y A T E L N P A F N S I E V R I T A Y N V W A V I N H F S N W L A T S L S I F Y L L K I A N F S N L I F L H L K R R V K S V V L V I L L G P L L F L V C H L F V I N M N Q I I W T K E Y E G N M T W K I K L R S A M Y L S N T T V T I L A N L V P F T L T L I S F L L L I C S L C K H L K K M Q L H G K G S Q D P S M K V H I K A L Q T V T S F L L L C A I Y F L S I I M S V W S F E S L E N K P V F M F C E A I A F S Y P S T H P F I L I W G N K K L K Q T F L S V L W H V R Y W V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XP4	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP4 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-		3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP5	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.08	2022-10-12	doi.org/10.1126/science.abo1633
	7XP5 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	-	-		3.08	2022-10-12	doi.org/10.1126/science.abo1633
	7XP6	T2	Sensory	Taste2	TAS2R46	Homo sapiens	Strychnine	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	doi.org/10.1126/science.abo1633
	7XP6 (No Gprot)	T2	Sensory	Taste2	TAS2R46	Homo sapiens	Strychnine	-		3.01	2022-10-12	doi.org/10.1126/science.abo1633

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7XP5_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.