psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F4	R:R:I8	6.28	No	No	0	4	5
2	R:R:F9	R:R:L5	3.65	Yes	No	0	3	4
3	R:R:I11	R:R:I7	2.94	No	No	0	6	5
4	R:R:I8	R:R:M262	5.83	No	No	0	5	4
5	R:R:F9	R:R:W66	5.01	Yes	Yes	0	3	4
6	R:R:F9	R:R:N257	4.83	Yes	No	0	3	3
7	R:R:F9	R:R:M262	12.44	Yes	No	0	3	4
8	R:R:L12	R:R:T16	2.95	No	Yes	0	6	7
9	R:R:A266	R:R:L12	3.15	No	No	0	4	6
10	R:R:I13	R:R:W66	3.52	No	Yes	1	4	4
11	R:R:F269	R:R:I13	6.28	Yes	No	1	4	4
12	R:R:F269	R:R:T16	9.08	Yes	Yes	1	4	7
13	R:R:S270	R:R:T16	6.4	No	Yes	1	5	7
14	R:R:S273	R:R:T16	3.2	Yes	Yes	1	8	7
15	R:R:F17	R:R:N21	3.62	No	No	4	5	5
16	R:R:F17	R:R:W60	16.04	No	No	4	5	1
17	R:R:F17	R:R:V63	5.24	No	No	0	5	4
18	R:R:I19	R:R:V18	3.07	Yes	No	0	5	5
19	R:R:I19	R:R:S273	4.64	Yes	Yes	0	5	8
20	R:R:F277	R:R:I19	3.77	No	Yes	0	5	5
21	R:R:G20	R:R:L59	3.42	No	No	0	9	7
22	R:R:N21	R:R:W60	4.52	No	No	4	5	1
23	R:R:A23	R:R:P276	3.74	No	No	0	7	9
24	R:R:N24	R:R:R55	7.23	No	Yes	0	9	9
25	R:R:N24	R:R:V56	2.96	No	No	0	9	6
26	R:R:N24	R:R:P276	9.77	No	No	0	9	9
27	R:R:F26	R:R:V30	7.87	Yes	Yes	2	8	8
28	R:R:F26	R:R:T289	5.19	Yes	No	2	8	6
29	R:R:F26	R:R:V293	3.93	Yes	No	0	8	6
30	R:R:I27	R:R:L279	2.85	Yes	No	0	9	9
31	R:R:I27	R:R:L286	4.28	Yes	Yes	0	9	9
32	R:R:L29	R:R:S32	4.5	No	No	5	6	4
33	R:R:I33	R:R:L29	4.28	No	No	5	5	6
34	R:R:N31	R:R:V30	2.96	Yes	Yes	2	8	8
35	R:R:L286	R:R:V30	2.98	Yes	Yes	2	9	8
36	R:R:T289	R:R:V30	6.35	No	Yes	2	6	8
37	R:R:D45	R:R:N31	6.73	Yes	Yes	2	8	8
38	R:R:N31	R:R:T49	5.85	Yes	No	0	8	6
39	R:R:K285	R:R:N31	5.6	Yes	Yes	2	8	8
40	R:R:I33	R:R:S32	3.1	No	No	5	5	4
41	R:R:E34	R:R:R38	12.79	Yes	No	0	6	5
42	R:R:E34	R:R:I41	6.83	Yes	Yes	2	6	6
43	R:R:D45	R:R:E34	10.39	Yes	Yes	2	8	6
44	R:R:E34	R:R:K285	6.75	Yes	Yes	2	6	8
45	R:R:I41	R:R:W35	10.57	Yes	No	0	6	5
46	R:R:K37	R:R:R38	6.19	No	No	0	7	5
47	R:R:D45	R:R:I41	8.4	Yes	Yes	2	8	6
48	R:R:I41	R:R:Q46	6.86	Yes	No	0	6	6
49	R:R:D45	R:R:S42	8.83	Yes	No	0	8	8
50	R:R:F105	R:R:F43	15	No	No	0	8	6
51	R:R:F43	R:R:K126	11.17	No	No	0	6	7
52	R:R:F43	R:R:V129	6.55	No	Yes	0	6	7
53	R:R:D45	R:R:K285	4.15	Yes	Yes	2	8	8
54	R:R:I47	R:R:L98	4.28	No	Yes	3	9	7
55	R:R:I47	R:R:S101	4.64	No	Yes	3	9	5
56	R:R:I47	R:R:L102	5.71	No	No	0	9	9
57	R:R:A50	R:R:L98	4.73	No	Yes	0	6	7
58	R:R:L51	R:R:R55	12.15	No	Yes	0	9	9
59	R:R:L51	R:R:L98	6.92	No	Yes	0	9	7
60	R:R:A99	R:R:L51	3.15	No	No	0	8	9
61	R:R:S54	R:R:S95	4.89	No	No	0	8	8
62	R:R:R55	R:R:S95	9.22	Yes	No	0	9	8
63	R:R:R55	R:R:Y271	16.46	Yes	Yes	1	9	6
64	R:R:P272	R:R:R55	2.88	Yes	Yes	1	8	9
65	R:R:H275	R:R:R55	12.41	Yes	Yes	1	9	9
66	R:R:I91	R:R:L58	2.85	No	No	0	5	4
67	R:R:L58	R:R:N92	6.87	No	Yes	0	4	8
68	R:R:L58	R:R:P272	6.57	No	Yes	0	4	8
69	R:R:L59	R:R:P272	8.21	No	Yes	0	7	8
70	R:R:V61	R:R:W88	7.36	No	Yes	0	4	4
71	R:R:L62	R:R:W88	3.42	No	Yes	1	4	4
72	R:R:F269	R:R:L62	8.53	Yes	No	1	4	4
73	L:L:?1	R:R:L62	2.88	Yes	No	1	0	4
74	R:R:V63	R:R:Y67	5.05	No	No	0	4	4
75	R:R:N65	R:R:T69	4.39	No	No	0	4	4
76	L:L:?1	R:R:N65	18.09	Yes	No	0	0	4
77	R:R:E70	R:R:W66	7.63	No	Yes	0	4	4
78	R:R:F269	R:R:W66	8.02	Yes	Yes	1	4	4
79	R:R:L71	R:R:Y67	5.86	No	No	0	4	4
80	R:R:A68	R:R:N76	6.25	No	Yes	0	3	3
81	R:R:F75	R:R:N72	8.46	No	Yes	0	2	3
82	R:R:N72	R:R:N76	5.45	Yes	Yes	0	3	3
83	R:R:N76	R:R:V80	8.87	Yes	No	0	3	2
84	R:R:N76	R:R:R81	3.62	Yes	No	0	3	3
85	R:R:I78	R:R:I82	2.94	No	No	0	4	2
86	R:R:I82	R:R:Q151	9.61	No	Yes	0	2	3
87	R:R:W88	R:R:Y85	2.89	Yes	No	1	4	2
88	R:R:V179	R:R:Y85	5.05	No	No	0	4	2
89	L:L:?1	R:R:Y85	4.88	Yes	No	1	0	2
90	R:R:I91	R:R:V87	3.07	No	No	0	5	3
91	R:R:N92	R:R:W88	10.17	Yes	Yes	1	8	4
92	L:L:?1	R:R:W88	34.75	Yes	Yes	1	0	4
93	R:R:A89	R:R:L144	3.15	No	No	0	5	5
94	R:R:L140	R:R:V90	2.98	No	No	0	5	6
95	R:R:N92	R:R:N96	9.54	Yes	Yes	1	8	6
96	R:R:N184	R:R:N92	6.81	Yes	Yes	1	5	8
97	R:R:H93	R:R:W97	13.75	No	Yes	1	5	7
98	R:R:H93	R:R:P136	3.05	No	No	1	5	8
99	R:R:H93	R:R:L140	21.86	No	No	0	5	5
100	R:R:F94	R:R:L137	3.65	No	No	0	5	4
101	R:R:N96	R:R:S95	2.98	Yes	No	0	6	8
102	R:R:N184	R:R:N96	5.45	Yes	Yes	1	5	6
103	R:R:N96	R:R:P187	9.77	Yes	No	1	6	8
104	R:R:T100	R:R:W97	3.64	No	Yes	0	8	7
105	R:R:P136	R:R:W97	21.62	No	Yes	1	8	7
106	R:R:V186	R:R:W97	3.68	No	Yes	1	6	7
107	R:R:P187	R:R:W97	14.86	No	Yes	1	8	7
108	R:R:L98	R:R:S101	3	Yes	Yes	3	7	5
109	R:R:L133	R:R:L98	4.15	No	Yes	3	8	7
110	R:R:T100	R:R:T191	6.28	No	Yes	0	8	8
111	R:R:S101	R:R:V129	3.23	Yes	Yes	3	5	7
112	R:R:L133	R:R:S101	7.51	No	Yes	3	8	5
113	R:R:L102	R:R:Y106	11.72	No	No	0	9	9
114	R:R:S103	R:R:T191	6.4	No	Yes	1	8	8
115	R:R:S103	R:R:S194	6.52	No	No	1	8	8
116	R:R:F195	R:R:S103	14.53	Yes	No	0	7	8
117	R:R:I104	R:R:L108	2.85	No	Yes	0	6	7
118	R:R:I104	R:R:S194	3.1	No	No	0	6	8
119	R:R:F105	R:R:K109	4.96	No	No	0	8	9
120	R:R:F195	R:R:Y106	3.09	Yes	No	0	7	9
121	R:R:F118	R:R:L107	6.09	No	No	0	9	8
122	R:R:L107	R:R:L197	4.15	No	No	0	8	7
123	R:R:L108	R:R:V125	4.47	Yes	No	0	7	7
124	R:R:L108	R:R:V128	4.47	Yes	No	0	7	6
125	R:R:I110	R:R:L198	4.28	No	No	0	9	9
126	R:R:A111	R:R:S201	3.42	No	No	0	8	9
127	R:R:N112	R:R:S201	2.98	No	No	0	8	9
128	R:R:F113	R:R:F118	15	No	No	0	8	9
129	R:R:F113	R:R:S201	5.28	No	No	0	8	9
130	R:R:I117	R:R:N115	9.91	No	No	0	5	8
131	R:R:H120	R:R:R124	6.77	No	No	0	5	7
132	R:R:L121	R:R:V128	2.98	No	No	0	8	6
133	R:R:K126	R:R:V125	3.04	No	No	0	7	7
134	R:R:L130	R:R:V129	2.98	No	Yes	0	6	7
135	R:R:L133	R:R:V129	2.98	No	Yes	3	8	7
136	R:R:I132	R:R:V131	3.07	No	No	0	6	4
137	R:R:G135	R:R:P136	4.06	No	No	0	5	8
138	R:R:G135	R:R:L138	5.13	No	No	0	5	4
139	R:R:L140	R:R:L144	6.92	No	No	0	5	5
140	R:R:H143	R:R:I147	6.63	Yes	No	0	6	4
141	R:R:H143	R:R:T178	5.48	Yes	No	0	6	3
142	R:R:F145	R:R:N148	3.62	No	No	0	3	3
143	R:R:I147	R:R:Q151	5.49	No	Yes	0	4	3
144	R:R:I153	R:R:M149	2.92	No	No	0	2	3
145	R:R:N150	R:R:W154	5.65	No	No	0	1	4
146	R:R:K156	R:R:Q151	6.78	No	Yes	0	2	3
147	R:R:T177	R:R:Y173	6.24	No	No	0	3	2
148	R:R:E253	R:R:Y173	6.73	No	No	0	2	2
149	R:R:F252	R:R:N176	3.62	No	No	0	2	3
150	R:R:N184	R:R:T180	2.92	Yes	No	0	5	2
151	L:L:?1	R:R:T180	3.07	Yes	No	0	0	2
152	R:R:I181	R:R:L185	2.85	No	Yes	0	5	3
153	R:R:L182	R:R:V186	4.47	No	No	0	4	6
154	R:R:N184	R:R:Y241	3.49	Yes	Yes	1	5	7
155	R:R:I245	R:R:N184	8.5	No	Yes	1	4	5
156	R:R:F242	R:R:L185	3.65	No	Yes	0	6	3
157	R:R:I245	R:R:L185	4.28	No	Yes	0	4	3
158	R:R:P187	R:R:V186	3.53	No	No	1	8	6
159	R:R:F188	R:R:T191	3.89	Yes	Yes	1	7	8
160	R:R:C238	R:R:F188	5.59	No	Yes	1	7	7
161	R:R:F188	R:R:Y241	10.32	Yes	Yes	1	7	7
162	R:R:F188	R:R:Y271	10.32	Yes	Yes	1	7	6
163	R:R:S194	R:R:T191	3.2	No	Yes	1	8	8
164	R:R:C238	R:R:T191	3.38	No	Yes	1	7	8
165	R:R:F195	R:R:V231	5.24	Yes	No	0	7	7
166	R:R:F195	R:R:F234	7.5	Yes	No	0	7	9
167	R:R:L198	R:R:V231	4.47	No	No	0	9	7
168	R:R:I199	R:R:L228	4.28	No	Yes	0	7	7
169	R:R:I199	R:R:V231	4.61	No	No	0	7	7
170	R:R:C200	R:R:K204	3.23	No	No	0	5	8
171	R:R:C203	R:R:L228	4.76	No	Yes	0	4	7
172	R:R:K204	R:R:K207	5.75	No	No	0	8	5
173	R:R:H205	R:R:K208	5.24	No	No	0	9	6
174	R:R:H205	R:R:M209	6.57	No	No	0	9	9
175	R:R:H205	R:R:H224	8.36	No	Yes	0	9	9
176	R:R:H224	R:R:L206	6.43	Yes	No	0	9	6
177	R:R:I225	R:R:L206	2.85	No	No	0	6	6
178	R:R:M209	R:R:M221	5.78	No	Yes	0	9	6
179	R:R:G213	R:R:K214	5.23	No	No	0	6	5
180	R:R:D218	R:R:K214	12.44	No	No	0	8	5
181	R:R:G215	R:R:M221	3.49	Yes	Yes	0	5	6
182	R:R:D218	R:R:P219	6.44	No	No	0	8	6
183	R:R:D218	R:R:S220	4.42	No	No	0	8	8
184	R:R:M221	R:R:S220	3.07	Yes	No	6	6	8
185	R:R:H224	R:R:S220	6.97	Yes	No	6	9	8
186	R:R:H224	R:R:M221	3.94	Yes	Yes	6	9	6
187	R:R:I225	R:R:Q229	5.49	No	No	0	6	7
188	R:R:T230	R:R:W281	6.06	No	Yes	0	8	5
189	R:R:G282	R:R:T230	5.46	No	No	0	8	8
190	R:R:I278	R:R:S233	6.19	Yes	No	1	8	8
191	R:R:S233	R:R:W281	6.18	No	Yes	1	8	5
192	R:R:F234	R:R:H275	3.39	No	Yes	1	9	9
193	R:R:F234	R:R:I278	6.28	No	Yes	1	9	8
194	R:R:H275	R:R:L237	6.43	Yes	No	1	9	7
195	R:R:I278	R:R:L237	2.85	Yes	No	1	8	7
196	R:R:I240	R:R:I267	2.94	No	No	0	6	5
197	R:R:I245	R:R:Y241	10.88	No	Yes	1	4	7
198	R:R:Y241	R:R:Y271	9.93	Yes	Yes	1	7	6
199	R:R:L243	R:R:M247	4.24	No	No	0	5	5
200	R:R:I267	R:R:S244	10.84	No	No	0	5	5
201	R:R:I246	R:R:W250	4.7	No	No	0	5	4
202	R:R:M247	R:R:W250	4.65	No	No	0	5	4
203	R:R:C264	R:R:M247	3.24	Yes	No	0	3	5
204	R:R:C264	R:R:S248	3.44	Yes	No	0	3	5
205	L:L:?1	R:R:S248	3.12	Yes	No	0	0	5
206	R:R:F261	R:R:S251	7.93	No	No	0	1	5
207	R:R:C264	R:R:S251	6.89	Yes	No	0	3	5
208	R:R:E256	R:R:L255	5.3	No	No	0	1	3
209	R:R:F261	R:R:N257	6.04	No	No	0	1	3
210	R:R:K258	R:R:P259	5.02	No	No	0	5	1
211	R:R:E265	R:R:F261	11.66	No	No	0	3	1
212	R:R:F263	R:R:I267	5.02	No	No	0	5	5
213	L:L:?1	R:R:E265	9.19	Yes	No	0	0	3
214	R:R:S270	R:R:S273	6.52	No	Yes	1	5	8
215	R:R:P272	R:R:Y271	4.17	Yes	Yes	1	8	6
216	R:R:H275	R:R:Y271	10.89	Yes	Yes	1	9	6
217	R:R:H275	R:R:I278	3.98	Yes	Yes	1	9	8
218	R:R:H275	R:R:L279	9	Yes	No	0	9	9
219	R:R:I278	R:R:W281	5.87	Yes	Yes	1	8	5
220	R:R:F290	R:R:I280	3.77	No	No	0	5	9
221	R:R:K287	R:R:W281	6.96	No	Yes	0	7	5
222	R:R:K285	R:R:N283	15.39	Yes	No	2	8	9
223	R:R:L286	R:R:N283	12.36	Yes	No	2	9	9
224	R:R:K285	R:R:L286	12.69	Yes	Yes	2	8	9
225	R:R:L294	R:R:R298	4.86	No	No	0	7	5
226	R:R:H296	R:R:W295	11.64	No	No	0	3	3
227	R:R:W295	R:R:Y299	19.29	No	No	0	3	3
228	R:R:V297	R:R:W300	9.81	No	No	0	6	3
229	R:R:I82	R:R:N86	2.83	No	No	0	2	3
230	R:R:K287	R:R:L291	2.82	No	No	0	7	5
231	R:R:H143	R:R:V146	2.77	Yes	No	0	6	3
232	R:R:H143	R:R:V179	2.77	Yes	No	0	6	4
233	R:R:L192	R:R:L235	2.77	No	No	0	7	7
234	R:R:L202	R:R:L228	2.77	No	Yes	0	9	7
235	R:R:A268	R:R:Y241	2.67	No	Yes	0	5	7
236	R:R:F94	R:R:S54	2.64	No	No	0	5	8
237	R:R:V56	R:R:W60	2.45	No	No	0	6	1
238	R:R:F118	R:R:L108	2.44	No	Yes	0	9	7
239	R:R:F139	R:R:L182	2.44	No	No	0	4	4
240	R:R:T155	R:R:W154	2.43	No	No	0	2	4
241	R:R:I132	R:R:W97	2.35	No	Yes	0	6	7
242	R:R:L190	R:R:W97	2.28	No	Yes	0	5	7
243	R:R:F26	R:R:F290	2.14	Yes	No	0	8	5
244	R:R:R123	R:R:R124	2.13	No	No	0	4	7
245	R:R:H296	R:R:W300	2.12	No	No	0	3	3
246	R:R:G215	R:R:S216	1.86	Yes	No	0	5	6
247	R:R:G57	R:R:V56	1.84	No	No	0	1	6
248	R:R:A28	R:R:A52	1.79	No	No	0	7	8
249	R:R:A44	R:R:S42	1.71	No	No	0	6	8
250	R:R:G135	R:R:L134	1.71	No	No	0	5	6
251	R:R:A268	R:R:S244	1.71	No	No	0	5	5
252	R:R:C264	R:R:V260	1.71	Yes	No	0	3	3
253	L:L:?1	R:R:F252	1.69	Yes	No	0	0	2
254	R:R:L5	R:R:P6	1.64	No	No	0	4	3
255	R:R:G215	R:R:Q210	1.64	Yes	No	0	5	6
256	R:R:G215	R:R:Q217	1.64	Yes	No	0	5	6
257	R:R:N72	R:R:P73	1.63	Yes	No	0	3	4
258	R:R:S10	R:R:V14	1.62	No	No	0	5	5
259	R:R:A52	R:R:I27	1.62	No	Yes	0	8	9
260	R:R:S292	R:R:V293	1.62	No	No	0	5	6
261	R:R:V14	R:R:V15	1.6	No	No	0	5	5
262	R:R:S270	R:R:T274	1.6	No	No	1	5	5
263	R:R:S273	R:R:T274	1.6	Yes	No	1	8	5
264	R:R:V293	R:R:V297	1.6	No	No	0	6	6
265	R:R:T180	R:R:V249	1.59	No	No	0	2	3
266	R:R:T177	R:R:T178	1.57	No	No	0	3	3
267	R:R:A183	R:R:N92	1.56	No	Yes	0	4	8
268	R:R:I78	R:R:S77	1.55	No	No	0	4	2
269	R:R:I11	R:R:V15	1.54	No	No	0	6	5
270	R:R:I13	R:R:V14	1.54	No	No	0	4	5
271	R:R:I19	R:R:V15	1.54	Yes	No	0	5	5
272	R:R:K258	R:R:S254	1.53	No	No	0	5	1
273	R:R:I7	R:R:T3	1.52	No	No	0	5	5
274	R:R:I78	R:R:T155	1.52	No	No	0	4	2
275	R:R:I199	R:R:T232	1.52	No	No	0	7	6
276	R:R:L174	R:R:T177	1.47	No	No	0	1	3
277	R:R:L185	R:R:T189	1.47	Yes	No	0	3	4
278	R:R:L190	R:R:T189	1.47	No	No	0	5	4
279	R:R:L236	R:R:T232	1.47	No	No	0	5	6
280	R:R:K222	R:R:K226	1.44	No	No	0	6	5
281	R:R:K226	R:R:K284	1.44	No	No	0	5	6
282	R:R:I27	R:R:L48	1.43	Yes	No	0	9	8
283	R:R:E79	R:R:V80	1.43	No	No	0	1	2
284	R:R:I117	R:R:L121	1.43	No	No	0	5	8
285	R:R:I193	R:R:L190	1.43	No	No	0	4	5
286	R:R:I193	R:R:L196	1.43	No	No	0	4	5
287	R:R:M149	R:R:N148	1.4	No	No	0	3	3
288	R:R:L116	R:R:L119	1.38	No	No	0	4	7
289	R:R:L196	R:R:L235	1.38	No	No	0	5	7
290	R:R:L206	R:R:L228	1.38	No	Yes	0	6	7
291	R:R:L71	R:R:N72	1.37	No	Yes	0	4	3
292	R:R:K207	R:R:Q210	1.36	No	No	0	5	6
293	R:R:R124	R:R:S127	1.32	No	No	0	7	5
294	R:R:N148	R:R:Q151	1.32	No	Yes	0	3	3
295	R:R:R298	R:R:V301	1.31	No	No	0	5	4
296	R:R:H120	R:R:L121	1.29	No	No	0	5	8
297	R:R:F290	R:R:L294	1.22	No	No	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F9	6.4825	4	0	3
2	R:R:T16	5.4075	4	1	7
3	R:R:I19	3.255	4	0	5
4	R:R:F26	4.7825	4	2	8
5	R:R:I27	2.545	4	0	9
6	R:R:V30	5.04	4	2	8
7	R:R:N31	5.285	4	2	8
8	R:R:E34	9.19	4	2	6
9	R:R:I41	8.165	4	2	6
10	R:R:D45	7.7	5	2	8
11	R:R:R55	10.0583	6	1	9
12	R:R:W66	6.045	4	1	4
13	R:R:N72	4.2275	4	0	3
14	R:R:N76	6.0475	4	0	3
15	R:R:W88	11.718	5	1	4
16	R:R:N92	6.99	5	1	8
17	R:R:N96	6.935	4	1	6
18	R:R:W97	8.88286	7	1	7
19	R:R:L98	4.616	5	3	7
20	R:R:S101	4.595	4	3	5
21	R:R:L108	3.5575	4	0	7
22	R:R:V129	3.935	4	3	7
23	R:R:H143	4.4125	4	0	6
24	R:R:Q151	5.8	4	0	3
25	R:R:N184	5.434	5	1	5
26	R:R:L185	3.0625	4	0	3
27	R:R:F188	7.53	4	1	7
28	R:R:T191	4.63	5	1	8
29	R:R:F195	7.59	4	0	7
30	R:R:G215	2.1575	4	0	5
31	R:R:M221	4.07	4	6	6
32	R:R:H224	6.425	4	6	9
33	R:R:L228	3.2975	4	0	7
34	R:R:Y241	7.458	5	1	7
35	R:R:C264	3.82	4	0	3
36	R:R:F269	7.9775	4	1	4
37	R:R:Y271	10.354	5	1	6
38	R:R:P272	5.4575	4	1	8
39	R:R:S273	3.99	4	1	8
40	R:R:H275	7.68333	6	1	9
41	R:R:I278	5.034	5	1	8
42	R:R:W281	6.2675	4	1	5
43	R:R:K285	8.916	5	2	8
44	R:R:L286	8.0775	4	2	9
45	L:L:?1	9.70875	8	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F9	R:R:W66	15.6133	5.01	Yes	Yes	0	3	4
2	R:R:I13	R:R:V14	15.8768	1.54	No	No	0	4	5
3	R:R:V14	R:R:V15	10.6783	1.6	No	No	0	5	5
4	R:R:F269	R:R:W66	20.413	8.02	Yes	Yes	1	4	4
5	R:R:F269	R:R:T16	26.3272	9.08	Yes	Yes	1	4	7
6	R:R:S273	R:R:T16	13.2384	3.2	Yes	Yes	1	8	7
7	R:R:F17	R:R:W60	15.421	16.04	No	No	4	5	1
8	R:R:V56	R:R:W60	17.942	2.45	No	No	0	6	1
9	R:R:N24	R:R:V56	20.3917	2.96	No	No	0	9	6
10	R:R:N24	R:R:R55	24.0128	7.23	No	Yes	0	9	9
11	R:R:R55	R:R:S95	36.9379	9.22	Yes	No	0	9	8
12	R:R:N96	R:R:S95	36.4963	2.98	Yes	No	0	6	8
13	R:R:N92	R:R:N96	32.6366	9.54	Yes	Yes	1	8	6
14	R:R:N92	R:R:W88	100	10.17	Yes	Yes	1	8	4
15	R:R:L62	R:R:W88	50.9204	3.42	No	Yes	1	4	4
16	R:R:F269	R:R:L62	66.3877	8.53	Yes	No	1	4	4
17	R:R:P272	R:R:R55	28.2001	2.88	Yes	Yes	1	8	9
18	R:R:L58	R:R:P272	44.4686	6.57	No	Yes	0	4	8
19	R:R:L58	R:R:N92	43.1654	6.87	No	Yes	0	4	8
20	R:R:F17	R:R:V63	14.214	5.24	No	No	0	5	4
21	R:R:F26	R:R:V30	23.5535	7.87	Yes	Yes	2	8	8
22	R:R:L286	R:R:V30	29.9056	2.98	Yes	Yes	2	9	8
23	R:R:I27	R:R:L286	59.3092	4.28	Yes	Yes	0	9	9
24	R:R:I27	R:R:L279	65.8145	2.85	Yes	No	0	9	9
25	R:R:H275	R:R:L279	67.4203	9	Yes	No	0	9	9
26	R:R:H275	R:R:R55	46.9503	12.41	Yes	Yes	1	9	9
27	R:R:H275	R:R:Y271	64.8816	10.89	Yes	Yes	1	9	6
28	R:R:P272	R:R:Y271	18.2945	4.17	Yes	Yes	1	8	6
29	R:R:Y241	R:R:Y271	46.1706	9.93	Yes	Yes	1	7	6
30	R:R:N184	R:R:Y241	69.514	3.49	Yes	Yes	1	5	7
31	R:R:N184	R:R:N92	28.7342	6.81	Yes	Yes	1	5	8
32	R:R:N184	R:R:T180	47.2067	2.92	Yes	No	0	5	2
33	L:L:?1	R:R:T180	45.7575	3.07	Yes	No	0	0	2
34	L:L:?1	R:R:L62	17.7889	2.88	Yes	No	1	0	4
35	R:R:F26	R:R:V293	12.861	3.93	Yes	No	0	8	6
36	R:R:K285	R:R:L286	26.4768	12.69	Yes	Yes	2	8	9
37	R:R:D45	R:R:K285	10.6106	4.15	Yes	Yes	2	8	8
38	R:R:E34	R:R:K285	10.7887	6.75	Yes	Yes	2	6	8
39	R:R:L51	R:R:L98	17.9847	6.92	No	Yes	0	9	7
40	R:R:L51	R:R:R55	20.0997	12.15	No	Yes	0	9	9
41	R:R:F188	R:R:Y241	28.1787	10.32	Yes	Yes	1	7	7
42	R:R:F188	R:R:T191	36.3361	3.89	Yes	Yes	1	7	8
43	R:R:S194	R:R:T191	17.1123	3.2	No	Yes	1	8	8
44	R:R:I104	R:R:S194	21.8444	3.1	No	No	0	6	8
45	R:R:I104	R:R:L108	20.7655	2.85	No	Yes	0	6	7
46	R:R:V63	R:R:Y67	12.9571	5.05	No	No	0	4	4
47	R:R:L71	R:R:Y67	11.6931	5.86	No	No	0	4	4
48	R:R:L71	R:R:N72	10.4219	1.37	No	Yes	0	4	3
49	R:R:W88	R:R:Y85	43.4609	2.89	Yes	No	1	4	2
50	R:R:V179	R:R:Y85	57.4292	5.05	No	No	0	4	2
51	R:R:H143	R:R:V179	55.0507	2.77	Yes	No	0	6	4
52	R:R:H143	R:R:I147	37.3189	6.63	Yes	No	0	6	4
53	R:R:I147	R:R:Q151	34.6982	5.49	No	Yes	0	4	3
54	R:R:I82	R:R:Q151	18.8214	9.61	No	Yes	0	2	3
55	R:R:I78	R:R:I82	13.4876	2.94	No	No	0	4	2
56	L:L:?1	R:R:Y85	16.3041	4.88	Yes	No	1	0	2
57	R:R:P187	R:R:W97	12.1595	14.86	No	Yes	1	8	7
58	R:R:N96	R:R:P187	14.7445	9.77	Yes	No	1	6	8
59	R:R:F234	R:R:H275	47.8868	3.39	No	Yes	1	9	9
60	R:R:F195	R:R:F234	48.7805	7.5	Yes	No	0	7	9
61	R:R:S103	R:R:T191	20.3027	6.4	No	Yes	1	8	8
62	R:R:F195	R:R:S103	25.7575	14.53	Yes	No	0	7	8
63	R:R:L108	R:R:V128	10.0694	4.47	Yes	No	0	7	6
64	R:R:F195	R:R:V231	62.7346	5.24	Yes	No	0	7	7
65	R:R:H143	R:R:T178	13.2918	5.48	Yes	No	0	6	3
66	R:R:N148	R:R:Q151	10.8065	1.32	No	Yes	0	3	3
67	R:R:T177	R:R:T178	10.6142	1.57	No	No	0	3	3
68	R:R:I199	R:R:V231	56.8809	4.61	No	No	0	7	7
69	R:R:I199	R:R:L228	50.7566	4.28	No	Yes	0	7	7
70	R:R:G215	R:R:M221	15.3748	3.49	Yes	Yes	0	5	6
71	R:R:H224	R:R:M221	19.4695	3.94	Yes	Yes	6	9	6
72	R:R:H224	R:R:L206	38.5437	6.43	Yes	No	0	9	6
73	R:R:L206	R:R:L228	44.5718	1.38	No	Yes	0	6	7
74	R:R:H224	R:R:S220	10.8207	6.97	Yes	No	6	9	8
75	R:R:H275	R:R:I278	10.9881	3.98	Yes	Yes	1	9	8
76	L:L:?1	R:R:S248	12.0847	3.12	Yes	No	0	0	5
77	R:R:C264	R:R:S248	10.632	3.44	Yes	No	0	3	5
78	R:R:F269	R:R:I13	18.0951	6.28	Yes	No	1	4	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:V61	R:R:W88	7.36	0	No	Yes	4	4	2	1
R:R:L62	R:R:W88	3.42	1	No	Yes	4	4	1	1
R:R:F269	R:R:L62	8.53	1	Yes	No	4	4	2	1
L:L:?1	R:R:L62	2.88	1	Yes	No	0	4	0	1
R:R:N65	R:R:T69	4.39	0	No	No	4	4	1	2
L:L:?1	R:R:N65	18.09	1	Yes	No	0	4	0	1
R:R:W88	R:R:Y85	2.89	1	Yes	No	4	2	1	1
R:R:V179	R:R:Y85	5.05	0	No	No	4	2	2	1
L:L:?1	R:R:Y85	4.88	1	Yes	No	0	2	0	1
R:R:N92	R:R:W88	10.17	1	Yes	Yes	8	4	2	1
L:L:?1	R:R:W88	34.75	1	Yes	Yes	0	4	0	1
R:R:N184	R:R:N92	6.81	1	Yes	Yes	5	8	2	2
R:R:F252	R:R:N176	3.62	0	No	No	2	3	1	2
R:R:N184	R:R:T180	2.92	1	Yes	No	5	2	2	1
L:L:?1	R:R:T180	3.07	1	Yes	No	0	2	0	1
R:R:C264	R:R:S248	3.44	0	Yes	No	3	5	2	1
L:L:?1	R:R:S248	3.12	1	Yes	No	0	5	0	1
R:R:E265	R:R:F261	11.66	0	No	No	3	1	1	2
L:L:?1	R:R:E265	9.19	1	Yes	No	0	3	0	1
L:L:?1	R:R:F252	1.69	1	Yes	No	0	2	0	1
R:R:T180	R:R:V249	1.59	0	No	No	2	3	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7XP6_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.85
Number of Linked Nodes	262
Number of Links	297
Number of Hubs	45
Number of Links mediated by Hubs	162
Number of Communities	6
Number of Nodes involved in Communities	59
Number of Links involved in Communities	82

Path Summary
Number Of Nodes in MetaPath	79
Number Of Links MetaPath	78
Number of Shortest Paths	66175
Length Of Smallest Path	3
Average Path Length	14.0408
Length of Longest Path	29
Minimum Path Strength	1.36
Average Path Strength	6.05831
Maximum Path Strength	22.46
Minimum Path Correlation	0.7
Average Path Correlation	0.935228
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	45.8505
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.1327
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • taste receptor activity • molecular transducer activity • bitter taste receptor activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled receptor activity • hydrolase activity, acting on glycosyl bonds • glucosidase activity • hydrolase activity, hydrolyzing O-glycosyl compounds • beta-glucosidase activity • cellulase activity • detection of chemical stimulus involved in sensory perception of bitter taste • detection of chemical stimulus involved in sensory perception of taste • detection of stimulus • detection of chemical stimulus • sensory perception of bitter taste • detection of stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception • carbohydrate metabolic process • catabolic process • glucan catabolic process • beta-glucan metabolic process • carbohydrate catabolic process • primary metabolic process • macromolecule catabolic process • polysaccharide metabolic process • glucan metabolic process • beta-glucan catabolic process • polysaccharide catabolic process • metabolic process • cellulose catabolic process • macromolecule metabolic process • cellulose metabolic process • ciliary membrane • plasma membrane region • cell projection membrane • cell surface
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	SY9
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	SY9
Name	Strychnine
Synonyms	Strychnidin-10-one
Identifier
Formula	C21 H22 N2 O2
Molecular Weight	334.412
SMILES
PubChem	441071
Formal Charge	0
Total Atoms	47
Total Chiral Atoms	7
Total Bonds	53
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P59540
Sequence	>7XP6_nogp_Chain_R T F L P I I F S I L I V V T F V I G N F A N G F I A L V N S I E W F K R Q K I S F A D Q I L T A L A V S R V G L L W V L V L N W Y A T E L N P A F N S I E V R I T A Y N V W A V I N H F S N W L A T S L S I F Y L L K I A N F S N L I F L H L K R R V K S V V L V I L L G P L L F L V C H L F V I N M N Q I I W T K Y L S N T T V T I L A N L V P F T L T L I S F L L L I C S L C K H L K K M Q L H G K G S Q D P S M K V H I K A L Q T V T S F L L L C A I Y F L S I I M S V W S F E S L E N K P V F M F C E A I A F S Y P S T H P F I L I W G N K K L K Q T F L S V L W H V R Y W V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XP6	T2	Sensory	Taste2	T2R46	Homo sapiens	Strychnine	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	10.1126/science.abo1633
	7XP6 (No Gprot)	T2	Sensory	Taste2	T2R46	Homo sapiens	Strychnine	-		3.01	2022-10-12	10.1126/science.abo1633
	7XP5	T2	Sensory	Taste2	T2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.08	2022-10-12	10.1126/science.abo1633
	7XP5 (No Gprot)	T2	Sensory	Taste2	T2R46	Homo sapiens	-	-		3.08	2022-10-12	10.1126/science.abo1633
	7XP4	T2	Sensory	Taste2	T2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/β1/γ2	3.01	2022-10-12	10.1126/science.abo1633
	7XP4 (No Gprot)	T2	Sensory	Taste2	T2R46	Homo sapiens	-	-		3.01	2022-10-12	10.1126/science.abo1633

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