psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F48	R:R:V44	3.93	No	No	0	4	5
2	R:R:F47	R:R:L46	4.87	No	No	0	4	5
3	R:R:F48	R:R:L51	3.65	No	No	0	4	4
4	R:R:M49	R:R:W328	30.24	No	Yes	0	6	5
5	R:R:D53	R:R:L50	5.43	No	No	0	7	3
6	R:R:L52	R:R:W328	6.83	No	Yes	0	6	5
7	R:R:C83	R:R:N60	6.3	No	Yes	0	9	9
8	R:R:D86	R:R:N60	12.12	Yes	Yes	0	9	9
9	R:R:N60	R:R:P338	13.03	Yes	No	0	9	9
10	R:R:C83	R:R:V63	5.12	No	No	0	9	9
11	R:R:F80	R:R:M64	7.46	No	Yes	0	5	7
12	R:R:L84	R:R:M64	5.65	No	Yes	0	5	7
13	R:R:L87	R:R:M64	7.07	No	Yes	0	7	7
14	R:R:L352	R:R:V66	5.96	Yes	No	0	7	7
15	R:R:F80	R:R:I67	7.54	No	No	0	5	7
16	R:R:E351	R:R:T70	11.29	No	No	0	8	6
17	R:R:F76	R:R:L73	3.65	Yes	No	3	9	8
18	R:R:L73	R:R:Q347	5.32	No	No	3	8	7
19	R:R:E351	R:R:L73	3.98	No	No	0	8	8
20	R:R:F76	R:R:K75	7.44	Yes	No	0	9	7
21	R:R:K75	R:R:Y143	4.78	No	No	0	7	8
22	R:R:F76	R:R:N345	12.08	Yes	No	3	9	9
23	R:R:F76	R:R:Q347	7.03	Yes	No	3	9	7
24	R:R:F76	R:R:I348	5.02	Yes	Yes	3	9	8
25	R:R:V159	R:R:V77	4.81	No	No	0	7	4
26	R:R:A135	R:R:F78	6.93	No	Yes	0	7	8
27	R:R:E139	R:R:F78	15.16	No	Yes	0	9	8
28	R:R:F78	R:R:V162	5.24	Yes	No	0	8	6
29	R:R:F78	R:R:L163	3.65	Yes	No	0	8	7
30	R:R:I136	R:R:V79	6.14	No	No	0	9	8
31	R:R:I348	R:R:V79	4.61	Yes	No	0	8	8
32	R:R:H81	R:R:V85	6.92	Yes	No	0	9	8
33	R:R:H81	R:R:S132	8.37	Yes	No	0	9	8
34	R:R:H81	R:R:L163	7.71	Yes	No	0	9	7
35	R:R:H81	R:R:W167	6.35	Yes	No	0	9	9
36	R:R:D86	R:R:L82	5.43	Yes	Yes	2	9	9
37	R:R:L82	R:R:S132	7.51	Yes	No	0	9	8
38	R:R:I136	R:R:L82	4.28	No	Yes	0	9	9
39	R:R:L82	R:R:N337	12.36	Yes	Yes	2	9	9
40	R:R:L84	R:R:L88	5.54	No	No	0	5	7
41	R:R:L128	R:R:V85	8.94	No	No	0	7	8
42	R:R:D86	R:R:F334	14.33	Yes	Yes	0	9	9
43	R:R:D86	R:R:N337	8.08	Yes	Yes	2	9	9
44	R:R:A89	R:R:F125	9.71	No	Yes	0	7	7
45	R:R:A89	R:R:F334	8.32	No	Yes	0	7	9
46	R:R:F125	R:R:T92	3.89	Yes	No	0	7	5
47	R:R:L93	R:R:S122	6.01	No	No	1	8	8
48	R:R:F125	R:R:L93	8.53	Yes	No	0	7	8
49	R:R:L93	R:R:Y331	12.89	No	Yes	1	8	8
50	R:R:M94	R:R:W328	5.82	No	Yes	0	7	5
51	R:R:A97	R:R:Y118	4	No	Yes	0	7	6
52	R:R:A97	R:R:W328	5.19	No	Yes	0	7	5
53	R:R:E112	R:R:R181	6.98	No	No	4	4	6
54	R:R:E112	R:R:E185	6.34	No	No	4	4	3
55	R:R:R116	R:R:V113	6.54	No	No	0	7	1
56	R:R:C115	R:R:C195	5.46	No	No	1	9	9
57	R:R:R116	R:R:V178	5.23	No	No	0	7	6
58	R:R:R116	R:R:R181	4.26	No	No	0	7	6
59	R:R:L117	R:R:L121	6.92	No	No	0	3	5
60	R:R:S122	R:R:Y118	8.9	No	Yes	1	8	6
61	R:R:Y118	R:R:Y331	5.96	Yes	Yes	1	6	8
62	R:R:F120	R:R:L121	4.87	Yes	No	0	6	5
63	R:R:A174	R:R:F120	5.55	No	Yes	0	8	6
64	R:R:F120	R:R:V178	3.93	Yes	No	0	6	6
65	R:R:F125	R:R:L121	4.87	Yes	No	0	7	5
66	R:R:S122	R:R:Y331	5.09	No	Yes	1	8	8
67	R:R:F212	R:R:V126	3.93	No	No	0	6	7
68	R:R:V126	R:R:W300	7.36	No	Yes	0	7	8
69	R:R:S127	R:R:Y216	10.17	No	Yes	0	7	6
70	R:R:L128	R:R:W167	19.36	No	No	0	7	9
71	R:R:A129	R:R:F334	4.16	No	Yes	0	9	9
72	R:R:I130	R:R:Y216	8.46	No	Yes	0	8	6
73	R:R:I130	R:R:W300	9.4	No	Yes	0	8	8
74	R:R:L131	R:R:V166	7.45	No	No	0	6	6
75	R:R:L131	R:R:Y216	10.55	No	Yes	0	6	6
76	R:R:V133	R:R:Y341	10.09	No	No	0	8	9
77	R:R:P220	R:R:S134	3.56	No	No	0	9	6
78	R:R:I136	R:R:R140	5.01	No	No	0	9	9
79	R:R:I224	R:R:N137	8.5	No	No	0	8	8
80	R:R:N137	R:R:Y341	10.47	No	No	0	8	9
81	R:R:R140	R:R:Y228	6.17	No	Yes	0	9	9
82	R:R:L344	R:R:R140	4.86	No	No	0	7	9
83	R:R:Y141	R:R:Y142	5.96	Yes	No	0	8	5
84	R:R:V145	R:R:Y141	12.62	No	Yes	0	6	8
85	R:R:V227	R:R:Y141	10.09	No	Yes	0	5	8
86	R:R:Y143	R:R:Y150	16.88	No	No	0	8	7
87	R:R:M231	R:R:V144	7.61	No	No	0	9	8
88	R:R:H146	R:R:V145	8.3	No	No	0	6	6
89	R:R:H146	R:R:R149	13.54	No	No	0	6	5
90	R:R:M154	R:R:Y150	16.76	No	No	0	6	7
91	R:R:G165	R:R:V164	3.68	No	No	0	1	2
92	R:R:K169	R:R:M173	10.08	No	No	5	4	6
93	R:R:K169	R:R:Y216	5.97	No	Yes	5	4	6
94	R:R:M173	R:R:Y216	8.38	No	Yes	5	6	6
95	R:R:V176	R:R:Y204	3.79	No	No	0	6	4
96	R:R:F208	R:R:V176	7.87	No	No	0	8	6
97	R:R:F208	R:R:P177	10.11	No	No	0	8	6
98	R:R:G180	R:R:W199	5.63	No	Yes	0	5	6
99	R:R:E185	R:R:R181	5.82	No	No	4	3	6
100	R:R:E185	R:R:V182	4.28	No	No	0	3	5
101	R:R:W184	R:R:W199	5.62	No	Yes	6	3	6
102	R:R:S200	R:R:W184	8.65	No	No	6	5	3
103	R:R:E323	R:R:S196	8.62	No	No	0	4	4
104	R:R:L197	R:R:Y303	4.69	No	Yes	7	6	7
105	R:R:H307	R:R:L197	9	No	No	7	6	6
106	R:R:Q198	R:R:V209	5.73	Yes	No	0	4	6
107	R:R:H307	R:R:Q198	12.36	No	Yes	0	6	4
108	R:R:Q198	R:R:V310	4.3	Yes	No	0	4	4
109	R:R:S200	R:R:W199	3.71	No	Yes	6	5	6
110	R:R:C205	R:R:W199	10.45	No	Yes	0	6	6
111	R:R:L207	R:R:Q206	3.99	No	No	0	3	4
112	R:R:A311	R:R:V209	5.09	No	No	0	6	6
113	R:R:F212	R:R:Y216	12.38	No	Yes	0	6	6
114	R:R:F212	R:R:F304	11.79	No	Yes	0	6	7
115	R:R:L215	R:R:Y216	7.03	No	Yes	0	5	6
116	R:R:F217	R:R:F296	5.36	No	Yes	0	8	9
117	R:R:F217	R:R:L301	7.31	No	No	0	8	6
118	R:R:F217	R:R:F304	12.86	No	Yes	0	8	7
119	R:R:L219	R:R:P220	4.93	No	No	0	5	9
120	R:R:L219	R:R:L223	4.15	No	No	0	5	6
121	R:R:F296	R:R:P220	5.78	Yes	No	0	9	9
122	R:R:L221	R:R:L297	5.54	No	No	0	6	5
123	R:R:I224	R:R:Y228	4.84	No	Yes	0	8	9
124	R:R:L289	R:R:Y228	4.69	No	Yes	0	8	9
125	R:R:V292	R:R:Y228	3.79	No	Yes	0	8	9
126	R:R:F232	R:R:R236	4.28	Yes	No	0	5	5
127	R:R:A285	R:R:F232	5.55	No	Yes	0	8	5
128	R:R:A286	R:R:F232	4.16	No	Yes	0	7	5
129	R:R:L344	R:R:V288	5.96	No	No	0	7	9
130	R:R:V292	R:R:Y341	3.79	No	No	0	8	9
131	R:R:F340	R:R:Q295	26.94	No	No	0	8	6
132	R:R:F296	R:R:W300	12.03	Yes	Yes	0	9	8
133	R:R:C299	R:R:W300	6.53	No	Yes	2	8	8
134	R:R:C299	R:R:C333	7.28	No	No	2	8	9
135	R:R:F304	R:R:W300	7.02	Yes	Yes	0	7	8
136	R:R:G330	R:R:W300	4.22	No	Yes	0	7	8
137	R:R:C333	R:R:W300	9.14	No	Yes	2	9	8
138	R:R:F304	R:R:Y303	9.28	Yes	Yes	0	7	7
139	R:R:H307	R:R:Y303	17.42	No	Yes	7	6	7
140	R:R:T327	R:R:Y303	7.49	No	Yes	0	6	7
141	R:R:F306	R:R:V310	7.87	Yes	No	0	5	4
142	R:R:F306	R:R:T319	9.08	Yes	No	8	5	5
143	R:R:F306	R:R:V322	10.49	Yes	No	8	5	5
144	R:R:F306	R:R:V326	3.93	Yes	No	0	5	5
145	R:R:T319	R:R:V322	4.76	No	No	8	5	5
146	R:R:E323	R:R:G320	4.91	No	No	0	4	1
147	R:R:Q321	R:R:V322	4.3	No	No	0	2	5
148	R:R:T327	R:R:Y331	6.24	No	Yes	0	6	8
149	R:R:W328	R:R:Y331	4.82	Yes	Yes	0	5	8
150	R:R:F334	R:R:Y331	6.19	Yes	Yes	0	9	8
151	R:R:F332	R:R:T335	5.19	No	No	0	4	6
152	R:R:C333	R:R:N337	6.3	No	Yes	2	9	9
153	R:R:N337	R:R:S336	4.47	Yes	No	0	9	5
154	R:R:F339	R:R:P338	5.78	No	No	0	6	9
155	R:R:I348	R:R:N345	11.33	Yes	No	3	8	9
156	R:R:R346	R:R:R349	10.66	No	No	0	7	9
157	R:R:K354	R:R:Q355	4.07	No	No	0	4	5
158	R:R:P177	R:R:V123	3.53	No	No	0	6	7
159	R:R:P302	R:R:V326	3.53	No	No	0	9	5
160	R:R:L119	R:R:Y118	3.52	No	Yes	1	5	6
161	R:R:P71	R:R:T70	3.5	No	No	0	6	6
162	R:R:E323	R:R:F306	3.5	No	Yes	0	4	5
163	R:R:C195	R:R:S100	3.44	No	No	0	9	5
164	R:R:A174	R:R:V123	3.39	No	No	0	8	7
165	R:R:A56	R:R:T335	3.36	No	No	0	7	6
166	R:R:C83	R:R:M64	3.24	No	Yes	0	9	7
167	R:R:P316	R:R:Q315	3.16	No	No	0	1	2
168	R:R:A170	R:R:L128	3.15	No	No	0	8	7
169	R:R:T335	R:R:T55	3.14	No	No	0	6	5
170	R:R:C205	R:R:Q198	3.05	No	Yes	0	6	4
171	R:R:L158	R:R:V162	2.98	No	No	0	6	6
172	R:R:L163	R:R:V159	2.98	No	No	0	7	7
173	R:R:M49	R:R:M98	2.89	No	No	0	6	6
174	R:R:Q295	R:R:S336	2.89	No	No	0	6	5
175	R:R:I348	R:R:L352	2.85	Yes	Yes	0	8	7
176	R:R:S230	R:R:Y141	2.54	No	Yes	0	5	8
177	R:R:S313	R:R:Y309	2.54	No	No	0	3	5
178	R:R:V227	R:R:Y228	2.52	No	Yes	0	5	9
179	R:R:F120	R:R:L171	2.44	Yes	No	0	6	3
180	R:R:F296	R:R:L221	2.44	Yes	No	0	9	6
181	R:R:F332	R:R:L298	2.44	No	No	0	4	4
182	R:R:L96	R:R:Y118	2.34	No	Yes	0	4	6
183	R:R:G293	R:R:G294	2.11	No	No	0	7	5
184	R:R:F306	R:R:Y309	2.06	Yes	No	0	5	5
185	R:R:A58	R:R:G59	1.95	No	No	0	3	9
186	R:R:A62	R:R:G59	1.95	No	No	0	7	9
187	R:R:A114	R:R:G111	1.95	No	No	0	4	8
188	R:R:P192	R:R:P193	1.95	No	No	0	3	3
189	R:R:G180	R:R:S183	1.86	No	No	0	5	4
190	R:R:G342	R:R:V79	1.84	No	No	0	7	8
191	R:R:G157	R:R:T155	1.82	No	No	0	4	8
192	R:R:A174	R:R:C124	1.81	No	No	0	8	5
193	R:R:A235	R:R:A285	1.79	No	No	0	8	8
194	R:R:C205	R:R:S202	1.72	No	No	0	6	3
195	R:R:G180	R:R:L179	1.71	No	No	0	5	4
196	R:R:G294	R:R:L297	1.71	No	No	0	5	5
197	R:R:A90	R:R:V57	1.7	No	No	0	7	6
198	R:R:I329	R:R:P302	1.69	No	No	0	7	9
199	R:R:A72	R:R:T70	1.68	No	No	0	5	6
200	R:R:M94	R:R:P95	1.68	No	No	0	7	9
201	R:R:S175	R:R:V176	1.62	No	No	0	5	6
202	R:R:S230	R:R:V226	1.62	No	No	0	5	4
203	R:R:A45	R:R:M49	1.61	No	No	0	5	6
204	R:R:A90	R:R:M94	1.61	No	No	0	7	7
205	R:R:V144	R:R:V145	1.6	No	No	0	8	6
206	R:R:V164	R:R:V168	1.6	No	No	0	2	3
207	R:R:V325	R:R:V326	1.6	No	No	0	4	5
208	R:R:C115	R:R:L119	1.59	No	No	1	9	5
209	R:R:C195	R:R:L119	1.59	No	No	1	9	5
210	R:R:C343	R:R:L352	1.59	No	Yes	0	5	7
211	R:R:A58	R:R:L54	1.58	No	No	0	3	4
212	R:R:A61	R:R:L87	1.58	No	No	0	4	7
213	R:R:A62	R:R:L352	1.58	No	Yes	0	7	7
214	R:R:A56	R:R:N60	1.56	No	Yes	0	7	9
215	R:R:H146	R:R:P147	1.53	No	No	0	6	9
216	R:R:H201	R:R:P316	1.53	No	No	0	5	1
217	R:R:M173	R:R:V211	1.52	No	No	0	6	3
218	R:R:A203	R:R:Q206	1.52	No	No	0	3	4
219	R:R:A314	R:R:Q315	1.52	No	No	0	3	2
220	R:R:I317	R:R:T319	1.52	No	No	0	1	5
221	R:R:L301	R:R:S305	1.5	No	No	0	6	5
222	R:R:G350	R:R:R349	1.5	No	No	0	5	9
223	R:R:L308	R:R:V210	1.49	No	No	0	5	5
224	R:R:L91	R:R:T92	1.47	No	No	0	4	5
225	R:R:D53	R:R:V57	1.46	No	No	0	7	6
226	R:R:Q315	R:R:S313	1.44	No	No	0	2	3
227	R:R:A213	R:R:F304	1.39	No	Yes	0	6	7
228	R:R:L96	R:R:L99	1.38	No	No	0	4	5
229	R:R:L221	R:R:L225	1.38	No	No	0	6	4
230	R:R:K69	R:R:Q355	1.36	No	No	0	6	5
231	R:R:E351	R:R:K354	1.35	No	No	0	8	4
232	R:R:S324	R:R:W328	1.24	No	Yes	0	5	5
233	R:R:F232	R:R:L289	1.22	Yes	No	0	5	8
234	R:R:F47	R:R:F48	1.07	No	No	0	4	4
235	R:R:R149	R:R:R153	1.07	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N60	8.2525	4	0	9
2	R:R:M64	5.855	4	0	7
3	R:R:F76	7.044	5	3	9
4	R:R:F78	7.745	4	0	8
5	R:R:H81	7.3375	4	0	9
6	R:R:L82	7.395	4	2	9
7	R:R:D86	9.99	4	2	9
8	R:R:Y118	4.944	5	1	6
9	R:R:F120	4.1975	4	0	6
10	R:R:F125	6.75	4	0	7
11	R:R:Y141	7.8025	4	0	8
12	R:R:Q198	6.36	4	0	4
13	R:R:W199	6.3525	4	6	6
14	R:R:Y216	8.99143	7	5	6
15	R:R:Y228	4.402	5	0	9
16	R:R:F232	3.8025	4	0	5
17	R:R:F296	6.4025	4	0	9
18	R:R:W300	7.95714	7	2	8
19	R:R:Y303	9.72	4	7	7
20	R:R:F304	8.468	5	0	7
21	R:R:F306	6.155	6	8	5
22	R:R:W328	9.02333	6	0	5
23	R:R:Y331	6.865	6	1	8
24	R:R:F334	8.25	4	0	9
25	R:R:N337	7.8025	4	2	9
26	R:R:I348	5.9525	4	3	8
27	R:R:L352	2.995	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:M94	R:R:W328	13.0885	5.82	No	Yes	0	7	5
2	R:R:C83	R:R:N60	18.4532	6.3	No	Yes	0	9	9
3	R:R:D86	R:R:N60	33.4701	12.12	Yes	Yes	0	9	9
4	R:R:D86	R:R:F334	79.5876	14.33	Yes	Yes	0	9	9
5	R:R:F334	R:R:Y331	53.9748	6.19	Yes	Yes	0	9	8
6	R:R:W328	R:R:Y331	25.7462	4.82	Yes	Yes	0	5	8
7	R:R:C83	R:R:M64	14.4733	3.24	No	Yes	0	9	7
8	R:R:I348	R:R:L352	16.4735	2.85	Yes	Yes	0	8	7
9	R:R:I348	R:R:V79	50.6103	4.61	Yes	No	0	8	8
10	R:R:I136	R:R:V79	54.303	6.14	No	No	0	9	8
11	R:R:I136	R:R:L82	100	4.28	No	Yes	0	9	9
12	R:R:D86	R:R:L82	70.2944	5.43	Yes	Yes	2	9	9
13	R:R:E351	R:R:L73	16.812	3.98	No	No	0	8	8
14	R:R:F76	R:R:L73	19.0891	3.65	Yes	No	3	9	8
15	R:R:F76	R:R:I348	32.2289	5.02	Yes	Yes	3	9	8
16	R:R:L82	R:R:S132	36.3935	7.51	Yes	No	0	9	8
17	R:R:H81	R:R:S132	34.2291	8.37	Yes	No	0	9	8
18	R:R:H81	R:R:L163	18.4737	7.71	Yes	No	0	9	7
19	R:R:F78	R:R:L163	11.7858	3.65	Yes	No	0	8	7
20	R:R:D86	R:R:N337	13.8989	8.08	Yes	Yes	2	9	9
21	R:R:A89	R:R:F334	26.6284	8.32	No	Yes	0	7	9
22	R:R:F125	R:R:L93	23.5819	8.53	Yes	No	0	7	8
23	R:R:L93	R:R:Y331	23.028	12.89	No	Yes	1	8	8
24	R:R:R116	R:R:V178	14.2579	5.23	No	No	0	7	6
25	R:R:F120	R:R:V178	16.5761	3.93	Yes	No	0	6	6
26	R:R:F120	R:R:L121	38.2808	4.87	Yes	No	0	6	5
27	R:R:F125	R:R:L121	42.4249	4.87	Yes	No	0	7	5
28	R:R:Y118	R:R:Y331	15.8683	5.96	Yes	Yes	1	6	8
29	R:R:A174	R:R:F120	18.6173	5.55	No	Yes	0	8	6
30	R:R:F304	R:R:Y303	57.3495	9.28	Yes	Yes	0	7	7
31	R:R:T327	R:R:Y303	64.5502	7.49	No	Yes	0	6	7
32	R:R:T327	R:R:Y331	65.2375	6.24	No	Yes	0	6	8
33	R:R:F304	R:R:W300	43.1121	7.02	Yes	Yes	0	7	8
34	R:R:I130	R:R:W300	11.0781	9.4	No	Yes	0	8	8
35	R:R:I136	R:R:R140	57.6982	5.01	No	No	0	9	9
36	R:R:R140	R:R:Y228	52.6721	6.17	No	Yes	0	9	9
37	R:R:F217	R:R:F304	14.4425	12.86	No	Yes	0	8	7
38	R:R:F217	R:R:F296	11.8269	5.36	No	Yes	0	8	9
39	R:R:F296	R:R:P220	12.5859	5.78	Yes	No	0	9	9
40	R:R:F296	R:R:W300	25.059	12.03	Yes	Yes	0	9	8
41	R:R:V227	R:R:Y228	28.2593	2.52	No	Yes	0	5	9
42	R:R:V227	R:R:Y141	25.9924	10.09	No	Yes	0	5	8
43	R:R:V145	R:R:Y141	16.8428	12.62	No	Yes	0	6	8
44	R:R:A174	R:R:V123	14.022	3.39	No	No	0	8	7
45	R:R:P177	R:R:V123	11.6832	3.53	No	No	0	6	7
46	R:R:C205	R:R:W199	17.212	10.45	No	Yes	0	6	6
47	R:R:C205	R:R:Q198	22.8023	3.05	No	Yes	0	6	4
48	R:R:H307	R:R:Q198	77.0028	12.36	No	Yes	0	6	4
49	R:R:H307	R:R:Y303	78.8183	17.42	No	Yes	7	6	7
50	R:R:Q198	R:R:V310	50.5385	4.3	Yes	No	0	4	4
51	R:R:F296	R:R:L221	15.6837	2.44	Yes	No	0	9	6
52	R:R:L289	R:R:Y228	14.5143	4.69	No	Yes	0	8	9
53	R:R:F232	R:R:L289	12.1243	1.22	Yes	No	0	5	8
54	R:R:C333	R:R:N337	61.0627	6.3	No	Yes	2	9	9
55	R:R:F306	R:R:V310	48.0049	7.87	Yes	No	0	5	4
56	R:R:F306	R:R:V326	11.4986	3.93	Yes	No	0	5	5
57	R:R:A56	R:R:N60	10.4524	1.56	No	Yes	0	7	9
58	R:R:F306	R:R:Y309	17.2223	2.06	Yes	No	0	5	5
59	R:R:S313	R:R:Y309	14.4015	2.54	No	No	0	3	5
60	R:R:Q315	R:R:S313	11.5602	1.44	No	No	0	2	3
61	R:R:A89	R:R:F125	24.9359	9.71	No	Yes	0	7	7
62	R:R:C333	R:R:W300	58.8471	9.14	No	Yes	2	9	8
63	R:R:L82	R:R:N337	50.0667	12.36	Yes	Yes	2	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8KGK_nogp

PDB Summary
PDB	8KGK_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.56
Number of Linked Nodes	224
Number of Links	235
Number of Hubs	27
Number of Links mediated by Hubs	111
Number of Communities	8
Number of Nodes involved in Communities	33
Number of Links involved in Communities	37

Path Summary
Number Of Nodes in MetaPath	64
Number Of Links MetaPath	63
Number of Shortest Paths	24344
Length Of Smallest Path	3
Average Path Length	11.5536
Length of Longest Path	24
Minimum Path Strength	1.48
Average Path Strength	7.03553
Maximum Path Strength	17.53
Minimum Path Correlation	0.7
Average Path Correlation	0.907495
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	47.3234
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.2712
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BZJ8
Sequence	>8KGK_nogp_Chain_R S V A L F F M L L L D L T A V A G N A A V M A V I A K T P A L R K F V F V F H L C L V D L L A A L T L M P L A M L S S S A G E V A C R L Y L F L S V C F V S L A I L S V S A I N V E R Y Y Y V V H P M R Y E V R M T L G L V A S V L V G V W V K A L A M A S V P V L G R V S W E P P G C S L Q W S H S A Y C Q L F V V V F A V L Y F L L P L L L I L V V Y C S M F R V A R V A G K A A V V L L A V G G Q F L L C W L P Y F S F H L Y V A L S A Q P I S T G Q V E S V V T W I G Y F C F T S N P F F Y G C L N R Q I R G E L S K Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8TB7	A	Orphan	Orphan	GPR61	Homo sapiens	-	PubChem 168510218	-	2.94	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB0	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB0 (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8KGK	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	Gs/β1/γ2	3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	8KGK (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8KGK_nogp.zip

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