psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F47	R:R:F48	13.93	No	No	0	4	4
2	R:R:M49	R:R:M98	10.11	No	No	2	6	6
3	R:R:M49	R:R:W328	8.14	No	Yes	2	6	5
4	R:R:L50	R:R:L51	4.15	No	No	0	3	4
5	R:R:L52	R:R:T55	2.95	No	No	0	6	5
6	R:R:D53	R:R:M94	13.86	No	No	0	7	7
7	R:R:D53	R:R:P95	3.22	No	No	0	7	9
8	R:R:T335	R:R:T55	7.85	No	No	0	6	5
9	R:R:A56	R:R:T335	3.36	No	No	0	7	6
10	R:R:D86	R:R:N60	13.46	No	Yes	1	9	9
11	R:R:L87	R:R:N60	6.87	No	Yes	0	7	9
12	R:R:N60	R:R:P338	6.52	Yes	No	1	9	9
13	R:R:I67	R:R:V63	3.07	No	No	0	7	9
14	R:R:C83	R:R:V63	10.25	No	No	0	9	9
15	R:R:F80	R:R:M64	4.98	No	No	0	5	7
16	R:R:I348	R:R:V66	3.07	No	No	0	8	7
17	R:R:I67	R:R:V79	3.07	No	No	0	7	8
18	R:R:I348	R:R:I67	2.94	No	No	0	8	7
19	R:R:L73	R:R:T70	8.84	Yes	Yes	4	8	6
20	R:R:E351	R:R:T70	5.64	No	Yes	4	8	6
21	R:R:P71	R:R:R74	7.21	No	No	0	6	8
22	R:R:E351	R:R:L73	6.63	No	Yes	4	8	8
23	R:R:F76	R:R:K75	12.41	No	No	0	9	7
24	R:R:F76	R:R:N345	9.67	No	No	0	9	9
25	R:R:V159	R:R:V77	6.41	Yes	No	0	7	4
26	R:R:E139	R:R:F78	13.99	No	Yes	0	9	8
27	R:R:F78	R:R:V159	10.49	Yes	Yes	0	8	7
28	R:R:I136	R:R:V79	3.07	Yes	No	0	9	8
29	R:R:H81	R:R:V85	6.92	Yes	No	3	9	8
30	R:R:H81	R:R:S132	5.58	Yes	No	0	9	8
31	R:R:H81	R:R:L163	9	Yes	No	0	9	7
32	R:R:H81	R:R:W167	5.29	Yes	No	3	9	9
33	R:R:L82	R:R:S132	7.51	No	No	0	9	8
34	R:R:L82	R:R:V133	2.98	No	No	0	9	8
35	R:R:I136	R:R:L82	5.71	Yes	No	0	9	9
36	R:R:L128	R:R:V85	4.47	No	No	3	7	8
37	R:R:V85	R:R:W167	6.13	No	No	3	8	9
38	R:R:D86	R:R:F334	7.17	No	Yes	1	9	9
39	R:R:D86	R:R:P338	3.22	No	No	1	9	9
40	R:R:F125	R:R:L88	4.87	No	No	0	7	7
41	R:R:A89	R:R:F125	5.55	No	No	0	7	7
42	R:R:A89	R:R:F334	4.16	No	Yes	0	7	9
43	R:R:L121	R:R:T92	2.95	No	No	0	5	5
44	R:R:L93	R:R:Y331	9.38	No	Yes	0	8	8
45	R:R:M94	R:R:W328	9.31	No	Yes	2	7	5
46	R:R:M94	R:R:Y331	4.79	No	Yes	2	7	8
47	R:R:L117	R:R:L96	4.15	No	No	0	3	4
48	R:R:L96	R:R:Y118	8.21	No	No	0	4	6
49	R:R:A97	R:R:Y118	4	No	No	0	7	6
50	R:R:A97	R:R:W328	5.19	No	Yes	0	7	5
51	R:R:M98	R:R:S102	4.6	No	No	0	6	5
52	R:R:M98	R:R:W328	3.49	No	Yes	2	6	5
53	R:R:A108	R:R:D106	3.09	No	No	0	8	4
54	R:R:L109	R:R:V113	4.47	No	No	0	3	1
55	R:R:F110	R:R:G111	3.01	Yes	No	5	5	8
56	R:R:F110	R:R:R116	6.41	Yes	No	5	5	7
57	R:R:C195	R:R:F110	8.38	No	Yes	0	9	5
58	R:R:G111	R:R:R116	6	No	No	5	8	7
59	R:R:E112	R:R:V113	4.28	No	No	0	4	1
60	R:R:C115	R:R:C195	7.28	No	No	0	9	9
61	R:R:F120	R:R:V178	3.93	Yes	No	0	6	6
62	R:R:S122	R:R:Y331	3.82	No	Yes	0	8	8
63	R:R:A174	R:R:V123	3.39	No	No	0	8	7
64	R:R:Q198	R:R:V123	4.3	No	No	0	4	7
65	R:R:C124	R:R:F125	4.19	No	No	0	5	7
66	R:R:I130	R:R:V126	3.07	No	No	1	8	7
67	R:R:V126	R:R:W300	7.36	No	Yes	1	7	8
68	R:R:F334	R:R:V126	3.93	Yes	No	1	9	7
69	R:R:A170	R:R:S127	3.42	No	No	0	8	7
70	R:R:S127	R:R:Y216	10.17	No	Yes	0	7	6
71	R:R:L128	R:R:W167	10.25	No	No	3	7	9
72	R:R:A170	R:R:L128	3.15	No	No	0	8	7
73	R:R:A129	R:R:F334	4.16	No	Yes	0	9	9
74	R:R:I130	R:R:Y216	3.63	No	Yes	0	8	6
75	R:R:I130	R:R:W300	8.22	No	Yes	1	8	8
76	R:R:L131	R:R:V166	2.98	No	No	0	6	6
77	R:R:L131	R:R:Y216	4.69	No	Yes	0	6	6
78	R:R:N337	R:R:V133	7.39	Yes	No	1	9	8
79	R:R:V133	R:R:Y341	5.05	No	Yes	1	8	9
80	R:R:L223	R:R:S134	6.01	Yes	No	0	6	6
81	R:R:I136	R:R:R140	5.01	Yes	No	1	9	9
82	R:R:I136	R:R:Y341	3.63	Yes	Yes	1	9	9
83	R:R:I224	R:R:N137	5.66	No	Yes	0	8	8
84	R:R:N137	R:R:Y228	3.49	Yes	Yes	0	8	9
85	R:R:N137	R:R:Y341	11.63	Yes	Yes	0	8	9
86	R:R:L223	R:R:V138	4.47	Yes	No	0	6	6
87	R:R:E139	R:R:Y150	5.61	No	No	0	9	7
88	R:R:R140	R:R:Y341	7.2	No	Yes	1	9	9
89	R:R:L344	R:R:R140	7.29	No	No	0	7	9
90	R:R:V145	R:R:Y141	11.36	No	No	0	6	8
91	R:R:V227	R:R:Y141	8.83	No	No	0	5	8
92	R:R:H146	R:R:Y142	5.44	Yes	No	0	6	5
93	R:R:Y143	R:R:Y150	10.92	No	No	0	8	7
94	R:R:H146	R:R:V145	8.3	Yes	No	0	6	6
95	R:R:M154	R:R:Y150	11.97	No	No	0	6	7
96	R:R:L163	R:R:V164	2.98	No	No	0	7	2
97	R:R:F208	R:R:M173	4.98	No	No	0	8	6
98	R:R:F212	R:R:M173	3.73	No	No	0	6	6
99	R:R:P177	R:R:V176	5.3	Yes	No	6	6	6
100	R:R:L179	R:R:V176	2.98	No	No	0	4	6
101	R:R:F208	R:R:V176	3.93	No	No	6	8	6
102	R:R:P177	R:R:Q198	3.16	Yes	No	0	6	4
103	R:R:F208	R:R:P177	5.78	No	Yes	6	8	6
104	R:R:G194	R:R:S200	3.71	No	No	0	3	5
105	R:R:L197	R:R:S196	3	No	No	0	6	4
106	R:R:L197	R:R:W199	3.42	No	Yes	8	6	6
107	R:R:H201	R:R:L197	7.71	No	No	8	5	6
108	R:R:H307	R:R:Q198	7.42	No	No	0	6	4
109	R:R:H201	R:R:W199	4.23	No	Yes	8	5	6
110	R:R:V209	R:R:W199	15.94	No	Yes	0	6	6
111	R:R:V310	R:R:W199	9.81	No	Yes	0	4	6
112	R:R:S200	R:R:S202	4.89	No	No	7	5	3
113	R:R:C205	R:R:S200	5.16	No	No	7	6	5
114	R:R:C205	R:R:S202	5.16	No	No	7	6	3
115	R:R:L207	R:R:V211	2.98	No	No	0	3	3
116	R:R:F212	R:R:Y216	4.13	No	Yes	0	6	6
117	R:R:F212	R:R:F304	6.43	No	No	0	6	7
118	R:R:A213	R:R:F304	4.16	No	No	0	6	7
119	R:R:L215	R:R:Y216	3.52	No	Yes	0	5	6
120	R:R:F217	R:R:F296	5.36	No	Yes	0	8	9
121	R:R:F217	R:R:L301	3.65	No	No	0	8	6
122	R:R:F217	R:R:F304	10.72	No	No	0	8	7
123	R:R:L219	R:R:P220	8.21	No	No	0	5	9
124	R:R:F296	R:R:P220	5.78	Yes	No	0	9	9
125	R:R:F296	R:R:L221	8.53	Yes	No	0	9	6
126	R:R:L221	R:R:L297	4.15	No	No	0	6	5
127	R:R:L222	R:R:V226	2.98	No	No	0	2	4
128	R:R:L223	R:R:V227	2.98	Yes	No	0	6	5
129	R:R:I224	R:R:V292	3.07	No	No	0	8	8
130	R:R:M231	R:R:Y228	4.79	No	Yes	0	9	9
131	R:R:L289	R:R:Y228	3.52	No	Yes	0	8	9
132	R:R:V292	R:R:Y228	10.09	No	Yes	0	8	9
133	R:R:A285	R:R:F232	5.55	No	No	0	8	5
134	R:R:G283	R:R:R236	3	No	No	0	5	5
135	R:R:F296	R:R:Q295	3.51	Yes	Yes	0	9	6
136	R:R:C333	R:R:Q295	6.1	Yes	Yes	1	9	6
137	R:R:Q295	R:R:S336	5.78	Yes	No	1	6	5
138	R:R:N337	R:R:Q295	6.6	Yes	Yes	1	9	6
139	R:R:F340	R:R:Q295	4.68	No	Yes	1	8	6
140	R:R:Q295	R:R:Y341	3.38	Yes	Yes	1	6	9
141	R:R:F296	R:R:W300	6.01	Yes	Yes	0	9	8
142	R:R:C299	R:R:W300	5.22	No	Yes	1	8	8
143	R:R:C299	R:R:C333	7.28	No	Yes	1	8	9
144	R:R:C333	R:R:W300	3.92	Yes	Yes	1	9	8
145	R:R:F334	R:R:W300	3.01	Yes	Yes	1	9	8
146	R:R:L301	R:R:P302	3.28	No	No	0	6	9
147	R:R:I329	R:R:P302	3.39	No	No	0	7	9
148	R:R:H307	R:R:Y303	6.53	No	No	0	6	7
149	R:R:T327	R:R:Y303	12.48	No	No	0	6	7
150	R:R:F306	R:R:V310	3.93	Yes	No	0	5	4
151	R:R:F306	R:R:T319	9.08	Yes	No	9	5	5
152	R:R:F306	R:R:V322	3.93	Yes	No	9	5	5
153	R:R:E323	R:R:F306	11.66	Yes	Yes	0	4	5
154	R:R:E323	R:R:H307	11.08	Yes	No	0	4	6
155	R:R:S313	R:R:Y309	5.09	No	No	0	3	5
156	R:R:I317	R:R:S313	6.19	No	No	0	1	3
157	R:R:T319	R:R:V322	3.17	No	No	9	5	5
158	R:R:G320	R:R:Q321	4.93	No	No	0	1	2
159	R:R:E323	R:R:T327	5.64	Yes	No	0	4	6
160	R:R:T327	R:R:Y331	6.24	No	Yes	0	6	8
161	R:R:W328	R:R:Y331	10.61	Yes	Yes	2	5	8
162	R:R:C333	R:R:S336	3.44	Yes	No	1	9	5
163	R:R:C333	R:R:N337	3.15	Yes	Yes	1	9	9
164	R:R:F340	R:R:S336	3.96	No	No	1	8	5
165	R:R:N337	R:R:Y341	4.65	Yes	Yes	1	9	9
166	R:R:C343	R:R:L344	3.17	No	No	0	5	7
167	R:R:I348	R:R:N345	5.66	No	No	0	8	9
168	R:R:Q321	R:R:S324	2.89	No	No	0	2	5
169	R:R:E323	R:R:V326	2.85	Yes	No	0	4	5
170	R:R:L84	R:R:M64	2.83	No	No	0	5	7
171	R:R:G330	R:R:W300	2.81	No	Yes	0	7	8
172	R:R:C124	R:R:F120	2.79	No	Yes	0	5	6
173	R:R:C299	R:R:F332	2.79	No	No	0	8	4
174	R:R:A135	R:R:F78	2.77	No	Yes	0	7	8
175	R:R:L121	R:R:L93	2.77	No	No	0	5	8
176	R:R:L96	R:R:L99	2.77	No	No	0	4	5
177	R:R:L117	R:R:L121	2.77	No	No	0	3	5
178	R:R:L223	R:R:N137	2.75	Yes	Yes	0	6	8
179	R:R:R233	R:R:S230	2.64	No	No	0	4	5
180	R:R:F78	R:R:V162	2.62	Yes	No	0	8	6
181	R:R:R116	R:R:V178	2.62	No	No	0	7	6
182	R:R:R153	R:R:V152	2.62	No	No	0	5	5
183	R:R:R233	R:R:V234	2.62	No	No	0	4	7
184	R:R:A311	R:R:W199	2.59	No	Yes	0	6	6
185	R:R:H107	R:R:L104	2.57	No	No	0	3	4
186	R:R:F48	R:R:L51	2.44	No	No	0	4	4
187	R:R:F120	R:R:L171	2.44	Yes	No	0	6	3
188	R:R:F332	R:R:L298	2.44	No	No	0	4	4
189	R:R:K169	R:R:Y216	2.39	No	Yes	0	4	6
190	R:R:Q347	R:R:R346	2.34	No	No	0	7	7
191	R:R:H146	R:R:R149	2.26	Yes	No	0	6	5
192	R:R:F232	R:R:R236	2.14	No	No	0	5	5
193	R:R:G293	R:R:G294	2.11	No	No	0	7	5
194	R:R:G59	R:R:P338	2.03	No	No	0	9	9
195	R:R:A58	R:R:G59	1.95	No	No	0	3	9
196	R:R:G165	R:R:V164	1.84	No	No	0	1	2
197	R:R:G165	R:R:V168	1.84	No	No	0	1	3
198	R:R:G320	R:R:V322	1.84	No	No	0	1	5
199	R:R:G157	R:R:T155	1.82	No	No	0	4	8
200	R:R:A56	R:R:A90	1.79	No	No	0	7	7
201	R:R:P71	R:R:T70	1.75	No	Yes	0	6	6
202	R:R:C229	R:R:S230	1.72	No	No	0	2	5
203	R:R:A90	R:R:V57	1.7	No	No	0	7	6
204	R:R:A114	R:R:V113	1.7	No	No	0	4	1
205	R:R:L119	R:R:P177	1.64	No	Yes	0	5	6
206	R:R:S100	R:R:S101	1.63	No	No	0	5	5
207	R:R:S101	R:R:S102	1.63	No	No	0	5	5
208	R:R:C83	R:R:M64	1.62	No	No	0	9	7
209	R:R:S230	R:R:V226	1.62	No	No	0	5	4
210	R:R:S324	R:R:V325	1.62	No	No	0	5	4
211	R:R:V145	R:R:V234	1.6	No	No	0	6	7
212	R:R:V210	R:R:V211	1.6	No	No	0	5	3
213	R:R:V210	R:R:V214	1.6	No	No	0	5	3
214	R:R:V288	R:R:V292	1.6	No	No	0	9	8
215	R:R:A45	R:R:L46	1.58	No	No	0	5	5
216	R:R:A72	R:R:L73	1.58	No	Yes	0	5	8
217	R:R:P316	R:R:Q315	1.58	No	No	0	1	2
218	R:R:A90	R:R:N60	1.56	No	Yes	0	7	9
219	R:R:A114	R:R:D106	1.54	No	No	0	4	4
220	R:R:H146	R:R:P147	1.53	Yes	No	0	6	9
221	R:R:M231	R:R:V144	1.52	No	No	0	9	8
222	R:R:F110	R:R:G194	1.51	Yes	No	0	5	3
223	R:R:K69	R:R:T70	1.5	No	Yes	0	6	6
224	R:R:G350	R:R:R349	1.5	No	No	0	5	9
225	R:R:L91	R:R:V57	1.49	No	No	0	4	6
226	R:R:L73	R:R:V66	1.49	Yes	No	0	8	7
227	R:R:L156	R:R:V159	1.49	No	Yes	0	4	7
228	R:R:L163	R:R:V159	1.49	No	Yes	0	7	7
229	R:R:L158	R:R:T155	1.47	No	No	0	6	8
230	R:R:L158	R:R:M154	1.41	No	No	0	6	6
231	R:R:A45	R:R:F47	1.39	No	No	0	5	4
232	R:R:H107	R:R:S100	1.39	No	No	0	3	5
233	R:R:L50	R:R:L54	1.38	No	No	0	3	4
234	R:R:L225	R:R:L289	1.38	No	No	0	4	8
235	R:R:L308	R:R:L312	1.38	No	No	0	5	4
236	R:R:D106	R:R:L99	1.36	No	No	0	4	5
237	R:R:F120	R:R:S175	1.32	Yes	No	0	6	5
238	R:R:R149	R:R:V152	1.31	No	No	0	5	5
239	R:R:L344	R:R:R349	1.21	No	No	0	7	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N60	7.1025	4	1	9
2	R:R:T70	4.4325	4	4	6
3	R:R:L73	4.635	4	4	8
4	R:R:F78	7.4675	4	0	8
5	R:R:H81	6.6975	4	3	9
6	R:R:F110	4.8275	4	5	5
7	R:R:F120	2.62	4	0	6
8	R:R:I136	4.355	4	1	9
9	R:R:N137	5.8825	4	0	8
10	R:R:H146	4.3825	4	0	6
11	R:R:V159	4.97	4	0	7
12	R:R:P177	3.97	4	6	6
13	R:R:W199	7.198	5	8	6
14	R:R:Y216	4.755	6	0	6
15	R:R:L223	4.0525	4	0	6
16	R:R:Y228	5.4725	4	0	9
17	R:R:Q295	5.00833	6	1	6
18	R:R:F296	5.838	5	0	9
19	R:R:W300	5.22143	7	1	8
20	R:R:F306	7.15	4	9	5
21	R:R:E323	7.8075	4	0	4
22	R:R:W328	7.348	5	2	5
23	R:R:Y331	6.968	5	2	8
24	R:R:C333	4.778	5	1	9
25	R:R:F334	4.486	5	1	9
26	R:R:N337	5.4475	4	1	9
27	R:R:Y341	5.92333	6	1	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:A90	R:R:N60	16.5087	1.56	No	Yes	0	7	9
2	R:R:D86	R:R:N60	20.9952	13.46	No	Yes	1	9	9
3	R:R:D86	R:R:F334	30.2617	7.17	No	Yes	1	9	9
4	R:R:F334	R:R:V126	18.3939	3.93	Yes	No	1	9	7
5	R:R:I130	R:R:V126	18.9966	3.07	No	No	1	8	7
6	R:R:I130	R:R:Y216	49.2686	3.63	No	Yes	0	8	6
7	R:R:F212	R:R:Y216	63.8251	4.13	No	Yes	0	6	6
8	R:R:F212	R:R:M173	100	3.73	No	No	0	6	6
9	R:R:F208	R:R:M173	99.454	4.98	No	No	0	8	6
10	R:R:F208	R:R:P177	96.7549	5.78	No	Yes	6	8	6
11	R:R:P177	R:R:Q198	96.6828	3.16	Yes	No	0	6	4
12	R:R:H307	R:R:Q198	94.9469	7.42	No	No	0	6	4
13	R:R:H307	R:R:Y303	39.2912	6.53	No	No	0	6	7
14	R:R:T327	R:R:Y303	38.4465	12.48	No	No	0	6	7
15	R:R:T327	R:R:Y331	77.3205	6.24	No	Yes	0	6	8
16	R:R:W328	R:R:Y331	39.9351	10.61	Yes	Yes	2	5	8
17	R:R:F334	R:R:W300	52.6012	3.01	Yes	Yes	1	9	8
18	R:R:I130	R:R:W300	30.818	8.22	No	Yes	1	8	8
19	R:R:E323	R:R:H307	55.1509	11.08	Yes	No	0	4	6
20	R:R:E323	R:R:T327	41.0065	5.64	Yes	No	0	4	6
21	R:R:F212	R:R:F304	38.0911	6.43	No	No	0	6	7
22	R:R:F217	R:R:F304	37.7614	10.72	No	No	0	8	7
23	R:R:F217	R:R:F296	38.8946	5.36	No	Yes	0	8	9
24	R:R:F296	R:R:Q295	50.6645	3.51	Yes	Yes	0	9	6
25	R:R:Q295	R:R:Y341	60.477	3.38	Yes	Yes	1	6	9
26	R:R:I136	R:R:Y341	34.13	3.63	Yes	Yes	1	9	9
27	R:R:I136	R:R:V79	30.4523	3.07	Yes	No	0	9	8
28	R:R:I67	R:R:V79	28.9121	3.07	No	No	0	7	8
29	R:R:I348	R:R:I67	19.6971	2.94	No	No	0	8	7
30	R:R:I348	R:R:V66	13.4285	3.07	No	No	0	8	7
31	R:R:L73	R:R:V66	11.7853	1.49	Yes	No	0	8	7
32	R:R:S127	R:R:Y216	26.929	10.17	No	Yes	0	7	6
33	R:R:A170	R:R:S127	25.5022	3.42	No	No	0	8	7
34	R:R:A170	R:R:L128	25.1365	3.15	No	No	0	8	7
35	R:R:L128	R:R:V85	12.6043	4.47	No	No	3	7	8
36	R:R:H81	R:R:V85	12.3262	6.92	Yes	No	3	9	8
37	R:R:H81	R:R:L163	33.3059	9	Yes	No	0	9	7
38	R:R:L163	R:R:V159	25.5898	1.49	No	Yes	0	7	7
39	R:R:L128	R:R:W167	12.6919	10.25	No	No	3	7	9
40	R:R:H81	R:R:W167	12.4086	5.29	Yes	No	3	9	9
41	R:R:F78	R:R:V159	19.6044	10.49	Yes	Yes	0	8	7
42	R:R:H81	R:R:S132	19.316	5.58	Yes	No	0	9	8
43	R:R:L82	R:R:V133	12.6764	2.98	No	No	0	9	8
44	R:R:C333	R:R:N337	19.3314	3.15	Yes	Yes	1	9	9
45	R:R:C333	R:R:W300	31.7812	3.92	Yes	Yes	1	9	8
46	R:R:A89	R:R:F125	36.6334	5.55	No	No	0	7	7
47	R:R:A89	R:R:F334	38.8586	4.16	No	Yes	0	7	9
48	R:R:L121	R:R:L93	25.1674	2.77	No	No	0	5	8
49	R:R:L93	R:R:Y331	27.1196	9.38	No	Yes	0	8	8
50	R:R:L117	R:R:L96	18.3682	4.15	No	No	0	3	4
51	R:R:L96	R:R:Y118	18.7391	8.21	No	No	0	4	6
52	R:R:A97	R:R:Y118	20.9849	4	No	No	0	7	6
53	R:R:A97	R:R:W328	22.9062	5.19	No	Yes	0	7	5
54	R:R:L117	R:R:L121	20.614	2.77	No	No	0	3	5
55	R:R:M98	R:R:S102	11.8677	4.6	No	No	0	6	5
56	R:R:D106	R:R:L99	27.7789	1.36	No	No	0	4	5
57	R:R:L96	R:R:L99	32.3735	2.77	No	No	0	4	5
58	R:R:A114	R:R:V113	13.9332	1.7	No	No	0	4	1
59	R:R:A114	R:R:D106	18.5588	1.54	No	No	0	4	4
60	R:R:F110	R:R:R116	16.4726	6.41	Yes	No	5	5	7
61	R:R:R116	R:R:V178	21.1342	2.62	No	No	0	7	6
62	R:R:F120	R:R:V178	23.4315	3.93	Yes	No	0	6	6
63	R:R:C124	R:R:F120	29.8908	2.79	No	Yes	0	5	6
64	R:R:C124	R:R:F125	32.1521	4.19	No	No	0	5	7
65	R:R:N137	R:R:Y341	48.0066	11.63	Yes	Yes	0	8	9
66	R:R:L223	R:R:N137	31.1837	2.75	Yes	Yes	0	6	8
67	R:R:L223	R:R:V227	26.3058	2.98	Yes	No	0	6	5
68	R:R:V227	R:R:Y141	24.5957	8.83	No	No	0	5	8
69	R:R:V145	R:R:Y141	23.0555	11.36	No	No	0	6	8
70	R:R:H146	R:R:V145	10.9354	8.3	Yes	No	0	6	6
71	R:R:E139	R:R:F78	13.5366	13.99	No	Yes	0	9	8
72	R:R:E139	R:R:Y150	11.8059	5.61	No	No	0	9	7
73	R:R:E323	R:R:F306	17.8428	11.66	Yes	Yes	0	4	5
74	R:R:V145	R:R:V234	10.7603	1.6	No	No	0	6	7
75	R:R:N137	R:R:Y228	12.0532	3.49	Yes	Yes	0	8	9
76	R:R:M98	R:R:W328	13.8302	3.49	No	Yes	2	6	5
77	R:R:F296	R:R:W300	14.9377	6.01	Yes	Yes	0	9	8
78	R:R:C333	R:R:Q295	13.6602	6.1	Yes	Yes	1	9	6
79	R:R:N337	R:R:Y341	13.3872	4.65	Yes	Yes	1	9	9
80	R:R:L82	R:R:S132	18.9811	7.51	No	No	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8TB0_nogp

PDB Summary
PDB	8TB0_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.94
Number of Linked Nodes	221
Number of Links	239
Number of Hubs	27
Number of Links mediated by Hubs	106
Number of Communities	9
Number of Nodes involved in Communities	44
Number of Links involved in Communities	55

Path Summary
Number Of Nodes in MetaPath	81
Number Of Links MetaPath	80
Number of Shortest Paths	38190
Length Of Smallest Path	3
Average Path Length	16.0344
Length of Longest Path	33
Minimum Path Strength	1.355
Average Path Strength	5.35351
Maximum Path Strength	11.585
Minimum Path Correlation	0.7
Average Path Correlation	0.923788
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	39.6159
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.7554
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9BZJ8
Sequence	>8TB0_nogp_Chain_R A L F F M L L L D L T A V A G N A A V M A V I A K T P A L R K F V F V F H L C L V D L L A A L T L M P L A M L S S S A L F D H A L F G E V A C R L Y L F L S V C F V S L A I L S V S A I N V E R Y Y Y V V H P M R Y E V R M T L G L V A S V L V G V W V K A L A M A S V P V L G G C S L Q W S H S A Y C Q L F V V V F A V L Y F L L P L L L I L V V Y C S M F R V A R V A G K A A V V L L A V G G Q F L L C W L P Y F S F H L Y V A L S A Q P I S T G Q V E S V V T W I G Y F C F T S N P F F Y G C L N R Q I R G E L S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8TB7	A	Orphan	Orphan	GPR61	Homo sapiens	-	PubChem 168510218	-	2.94	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB0	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB0 (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8KGK	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	Gs/β1/γ2	3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	8KGK (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8TB0_nogp.zip

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