psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:Q153	L:L:Y149	12.4	No	No	4	6	5
2	L:L:F154	L:L:Y149	6.19	Yes	No	4	6	5
3	L:L:Y149	R:R:F294	7.22	No	Yes	0	5	5
4	L:L:F150	R:R:F190	18.22	No	Yes	0	4	3
5	L:L:P151	R:R:H217	7.63	No	Yes	1	9	4
6	L:L:P151	R:R:E283	4.72	No	No	1	9	4
7	L:L:P151	R:R:H286	7.63	No	No	0	9	2
8	L:L:G152	L:L:S157	3.71	No	No	5	9	5
9	L:L:G152	R:R:N191	3.39	No	Yes	5	9	5
10	L:L:F154	L:L:Q153	10.54	Yes	No	4	6	6
11	L:L:F154	R:R:Y103	12.38	Yes	Yes	0	6	4
12	L:L:F154	R:R:S295	5.28	Yes	No	0	6	4
13	L:L:A155	R:R:L298	3.15	No	No	0	9	4
14	L:L:F156	R:R:H95	9.05	No	No	0	9	6
15	L:L:F156	R:R:Y276	6.19	No	Yes	0	9	6
16	L:L:F156	R:R:T302	3.89	No	No	0	9	6
17	L:L:S157	R:R:N191	8.94	No	Yes	5	5	5
18	L:L:S157	R:R:R224	3.95	No	Yes	0	5	5
19	R:R:R37	R:R:R40	6.4	No	No	0	3	4
20	R:R:L43	R:R:Y47	12.89	No	Yes	0	6	8
21	R:R:A100	R:R:V44	3.39	No	No	0	5	5
22	R:R:I49	R:R:V45	3.07	No	No	0	4	5
23	R:R:A303	R:R:Y47	5.34	No	Yes	0	5	8
24	R:R:I306	R:R:V50	4.61	No	No	0	7	7
25	R:R:C310	R:R:V50	3.42	No	No	0	8	7
26	R:R:C51	R:R:P93	3.77	No	No	0	6	8
27	R:R:L53	R:R:L56	4.15	No	No	0	5	5
28	R:R:G54	R:R:N89	3.39	No	Yes	0	8	6
29	R:R:F86	R:R:I55	3.77	No	No	0	8	5
30	R:R:G57	R:R:L56	5.13	No	No	0	7	5
31	R:R:D85	R:R:N58	13.46	Yes	No	0	9	9
32	R:R:N58	R:R:P313	9.77	No	No	0	9	9
33	R:R:A82	R:R:V61	3.39	No	No	0	8	9
34	R:R:V317	R:R:V61	8.02	No	No	0	7	9
35	R:R:I62	R:R:V83	3.07	No	No	0	7	6
36	R:R:F67	R:R:I63	5.02	No	No	0	5	3
37	R:R:D322	R:R:I64	4.2	No	No	0	6	7
38	R:R:A65	R:R:L79	3.15	No	No	0	6	5
39	R:R:F67	R:R:T66	3.89	No	No	0	5	4
40	R:R:F67	R:R:K68	7.44	No	No	0	5	4
41	R:R:F326	R:R:K68	9.93	No	No	0	4	4
42	R:R:M69	R:R:M75	13	No	Yes	7	5	8
43	R:R:D322	R:R:M69	13.86	No	No	7	6	5
44	R:R:V73	R:R:W77	3.68	No	Yes	0	6	7
45	R:R:F78	R:R:N74	3.62	Yes	No	0	8	8
46	R:R:D322	R:R:M75	4.16	No	Yes	7	6	8
47	R:R:A156	R:R:V76	5.09	No	No	0	7	6
48	R:R:V76	R:R:Y157	8.83	No	No	0	6	3
49	R:R:I132	R:R:W77	9.4	No	Yes	0	6	7
50	R:R:I133	R:R:W77	4.7	No	Yes	0	9	7
51	R:R:D136	R:R:W77	4.47	No	Yes	0	8	7
52	R:R:A156	R:R:W77	5.19	No	Yes	0	7	7
53	R:R:F78	R:R:Y316	3.09	Yes	Yes	0	8	9
54	R:R:F78	R:R:V317	5.24	Yes	No	0	8	7
55	R:R:C160	R:R:N80	11.02	No	No	0	7	9
56	R:R:N80	R:R:W164	3.39	No	Yes	0	9	9
57	R:R:D85	R:R:L81	5.43	Yes	No	0	9	9
58	R:R:L129	R:R:L81	4.15	No	No	0	8	9
59	R:R:D85	R:R:S126	4.42	Yes	No	0	9	9
60	R:R:D85	R:R:S309	5.89	Yes	No	0	9	9
61	R:R:D85	R:R:N312	6.73	Yes	No	0	9	9
62	R:R:L87	R:R:N122	5.49	No	No	0	7	8
63	R:R:F88	R:R:N89	3.62	Yes	Yes	0	8	6
64	R:R:F88	R:R:L119	7.31	Yes	No	0	8	6
65	R:R:F88	R:R:N122	6.04	Yes	No	0	8	8
66	R:R:F88	R:R:I306	3.77	Yes	No	0	8	7
67	R:R:N89	R:R:S309	5.96	Yes	No	0	6	9
68	R:R:F91	R:R:V90	7.87	No	No	0	6	5
69	R:R:F91	R:R:L118	7.31	No	No	0	6	5
70	R:R:L92	R:R:P93	3.28	No	No	6	8	8
71	R:R:I96	R:R:L92	4.28	Yes	No	6	7	8
72	R:R:I306	R:R:L92	4.28	No	No	0	7	8
73	R:R:I96	R:R:P93	3.39	Yes	No	6	7	8
74	R:R:I94	R:R:W105	3.52	No	Yes	3	6	9
75	R:R:F107	R:R:I94	5.02	Yes	No	3	8	6
76	R:R:I94	R:R:M111	4.37	No	No	0	6	6
77	R:R:H95	R:R:Y98	6.53	No	No	0	6	5
78	R:R:F107	R:R:T97	5.19	Yes	No	0	8	4
79	R:R:Y103	R:R:Y98	11.91	Yes	No	0	4	5
80	R:R:W105	R:R:Y98	11.58	Yes	No	0	9	5
81	R:R:A99	R:R:Y103	5.34	No	Yes	0	5	4
82	R:R:M101	R:R:V106	4.56	No	No	0	4	3
83	R:R:D102	R:R:K186	11.06	No	No	0	4	2
84	R:R:H104	R:R:I187	11.93	No	No	0	5	5
85	R:R:F107	R:R:W105	23.05	Yes	Yes	3	8	9
86	R:R:C112	R:R:W105	7.84	No	Yes	3	9	9
87	R:R:C189	R:R:W105	5.22	No	Yes	3	9	9
88	R:R:F107	R:R:V106	7.87	Yes	No	0	8	3
89	R:R:T109	R:R:T180	3.14	Yes	No	0	3	4
90	R:R:M111	R:R:S115	3.07	No	No	0	6	5
91	R:R:C112	R:R:T180	3.38	No	No	0	9	4
92	R:R:C112	R:R:C189	7.28	No	No	3	9	9
93	R:R:F117	R:R:I114	5.02	Yes	No	9	5	4
94	R:R:I114	R:R:L118	5.71	No	No	9	4	5
95	R:R:N116	R:R:R178	21.69	No	Yes	0	6	5
96	R:R:F117	R:R:L118	4.87	Yes	No	9	5	5
97	R:R:F117	R:R:F168	4.29	Yes	No	0	5	3
98	R:R:F117	R:R:S171	6.61	Yes	No	0	5	7
99	R:R:F117	R:R:L175	18.27	Yes	No	0	5	4
100	R:R:I120	R:R:S171	3.1	No	No	0	4	7
101	R:R:I120	R:R:R224	6.26	No	Yes	0	4	5
102	R:R:H121	R:R:W164	7.41	No	Yes	0	5	9
103	R:R:F168	R:R:H121	3.39	No	No	0	3	5
104	R:R:H121	R:R:S171	5.58	No	No	0	5	7
105	R:R:F124	R:R:M123	6.22	Yes	No	0	7	8
106	R:R:M123	R:R:W273	4.65	No	Yes	0	8	9
107	R:R:F124	R:R:L170	6.09	Yes	No	0	7	5
108	R:R:F124	R:R:R224	4.28	Yes	Yes	0	7	5
109	R:R:F124	R:R:G228	4.52	Yes	No	0	7	6
110	R:R:T125	R:R:W164	12.13	No	Yes	0	7	9
111	R:R:A167	R:R:T125	3.36	No	No	0	8	7
112	R:R:P232	R:R:V127	3.53	No	No	0	9	7
113	R:R:V127	R:R:W273	3.68	No	Yes	0	7	9
114	R:R:F128	R:R:I163	5.02	No	No	0	6	7
115	R:R:I163	R:R:L129	4.28	No	No	0	7	8
116	R:R:L130	R:R:N312	4.12	No	No	0	8	9
117	R:R:L130	R:R:Y316	8.21	No	Yes	0	8	9
118	R:R:P232	R:R:T131	3.5	No	No	0	9	7
119	R:R:I235	R:R:T131	6.08	No	No	0	7	7
120	R:R:I236	R:R:T131	3.04	No	No	0	8	7
121	R:R:I132	R:R:I163	4.42	No	No	0	6	7
122	R:R:I133	R:R:R137	5.01	No	No	8	9	9
123	R:R:I133	R:R:Y316	4.84	No	Yes	8	9	9
124	R:R:I236	R:R:S134	4.64	No	No	0	8	9
125	R:R:C239	R:R:S134	5.16	No	No	0	7	9
126	R:R:S134	R:R:Y240	6.36	No	Yes	0	9	9
127	R:R:I139	R:R:S135	3.1	No	No	0	5	6
128	R:R:D136	R:R:R151	11.91	No	No	0	8	6
129	R:R:R137	R:R:Y240	8.23	No	Yes	0	9	9
130	R:R:R137	R:R:Y316	6.17	No	Yes	8	9	9
131	R:R:C138	R:R:L142	3.17	Yes	No	10	8	7
132	R:R:C138	R:R:C239	7.28	Yes	No	0	8	7
133	R:R:C138	R:R:T242	3.38	Yes	No	10	8	4
134	R:R:C138	R:R:I243	3.27	Yes	No	0	8	8
135	R:R:S140	R:R:S147	3.26	No	No	0	7	4
136	R:R:I243	R:R:V141	3.07	No	No	0	8	8
137	R:R:L142	R:R:T242	4.42	No	No	10	7	4
138	R:R:K246	R:R:L142	5.64	No	No	0	5	7
139	R:R:H150	R:R:W146	21.16	No	No	0	4	4
140	R:R:R151	R:R:S147	3.95	No	No	0	6	4
141	R:R:H150	R:R:N149	3.83	No	No	0	4	4
142	R:R:R154	R:R:S152	3.95	No	No	0	5	6
143	R:R:L155	R:R:S152	4.5	No	No	0	3	6
144	R:R:V153	R:R:Y157	5.05	No	No	0	2	3
145	R:R:P173	R:R:S172	3.56	No	No	0	8	4
146	R:R:R178	R:R:S174	5.27	Yes	No	0	5	5
147	R:R:F177	R:R:F193	15	No	Yes	0	4	5
148	R:R:C189	R:R:R178	6.96	No	Yes	0	9	5
149	R:R:N191	R:R:R178	8.44	Yes	Yes	0	5	5
150	R:R:D179	R:R:N192	10.77	No	No	0	4	2
151	R:R:I187	R:R:N182	8.5	No	No	0	5	1
152	R:R:F190	R:R:S188	3.96	Yes	No	0	3	4
153	R:R:F190	R:R:N192	6.04	Yes	No	0	3	2
154	R:R:F193	R:R:N191	3.62	Yes	Yes	0	5	5
155	R:R:F193	R:R:R216	4.28	Yes	Yes	0	5	4
156	R:R:F193	R:R:H217	18.1	Yes	Yes	0	5	4
157	R:R:S194	R:R:V212	4.85	No	No	0	3	3
158	R:R:L195	R:R:R216	3.64	No	Yes	0	4	4
159	R:R:D210	R:R:P211	11.27	No	No	0	4	2
160	R:R:D210	R:R:V212	5.84	No	No	0	4	3
161	R:R:G213	R:R:R216	4.5	No	Yes	0	3	4
162	R:R:M218	R:R:Y214	3.59	No	No	1	1	1
163	R:R:L284	R:R:Y214	15.24	No	No	1	5	1
164	R:R:H217	R:R:T221	6.85	Yes	No	0	4	6
165	R:R:E283	R:R:H217	7.39	No	Yes	1	4	4
166	R:R:H217	R:R:L284	7.71	Yes	No	1	4	5
167	R:R:M218	R:R:V222	3.04	No	No	0	1	4
168	R:R:L284	R:R:M218	4.24	No	No	1	5	1
169	R:R:F225	R:R:L226	3.65	No	No	0	5	4
170	R:R:F225	R:R:H277	3.39	No	No	0	5	8
171	R:R:F229	R:R:F269	5.36	Yes	No	2	9	9
172	R:R:F229	R:R:F270	5.36	Yes	No	2	9	6
173	R:R:F229	R:R:W273	5.01	Yes	Yes	2	9	9
174	R:R:C274	R:R:F229	4.19	Yes	Yes	2	6	9
175	R:R:F229	R:R:H277	5.66	Yes	No	2	9	8
176	R:R:P232	R:R:V231	3.53	No	No	0	9	6
177	R:R:I235	R:R:V231	3.07	No	No	0	7	6
178	R:R:F269	R:R:V233	5.24	No	No	0	9	5
179	R:R:I262	R:R:Y240	8.46	No	Yes	0	8	9
180	R:R:I265	R:R:Y240	6.04	No	Yes	0	8	9
181	R:R:F259	R:R:V244	3.93	No	No	0	7	5
182	R:R:I262	R:R:V244	3.07	No	No	0	8	5
183	R:R:K246	R:R:R249	8.66	No	No	0	5	5
184	R:R:A253	R:R:L247	4.73	No	No	0	5	8
185	R:R:L247	R:R:P258	3.28	No	No	0	8	7
186	R:R:F259	R:R:L247	7.31	No	No	0	7	8
187	R:R:N250	R:R:R249	7.23	No	No	0	5	5
188	R:R:L252	R:R:N250	5.49	No	No	0	3	5
189	R:R:F259	R:R:K256	7.44	No	No	0	7	5
190	R:R:K256	R:R:K260	11.49	No	No	0	5	5
191	R:R:K257	R:R:P258	3.35	No	No	0	7	7
192	R:R:K257	R:R:M319	5.76	No	No	0	7	6
193	R:R:I261	R:R:M319	7.29	No	No	0	8	6
194	R:R:L315	R:R:T264	5.9	No	No	0	7	5
195	R:R:I265	R:R:Y316	8.46	No	Yes	0	8	9
196	R:R:M311	R:R:T268	6.02	No	No	0	6	7
197	R:R:F269	R:R:W273	13.03	No	Yes	2	9	9
198	R:R:C274	R:R:F270	9.78	Yes	No	2	6	6
199	R:R:C272	R:R:N308	3.15	No	No	0	9	9
200	R:R:H277	R:R:W273	6.35	No	Yes	2	8	9
201	R:R:N308	R:R:W273	9.04	No	Yes	0	9	9
202	R:R:C274	R:R:P275	3.77	Yes	No	0	6	9
203	R:R:L304	R:R:P275	3.28	No	No	0	7	9
204	R:R:N280	R:R:Y276	10.47	No	Yes	0	5	6
205	R:R:L279	R:R:L298	4.15	No	No	0	4	4
206	R:R:L282	R:R:M289	4.24	No	No	0	5	3
207	R:R:F294	R:R:L282	3.65	Yes	No	0	5	5
208	R:R:E283	R:R:F294	3.5	No	Yes	0	4	5
209	R:R:P290	R:R:S292	3.56	No	No	0	1	4
210	R:R:G297	R:R:L296	3.42	No	No	0	5	1
211	R:R:F318	R:R:P313	4.33	Yes	No	0	6	9
212	R:R:F318	R:R:I314	3.77	Yes	No	0	6	6
213	R:R:F318	R:R:F323	20.36	Yes	No	0	6	8
214	R:R:F323	R:R:K327	6.2	No	No	0	8	6
215	R:R:F326	R:R:K325	6.2	No	No	0	4	5
216	R:R:M75	R:R:T72	3.01	Yes	No	0	8	7
217	R:R:K113	R:R:T109	3	No	Yes	0	7	3
218	R:R:K257	R:R:T255	3	No	No	0	7	6
219	R:R:L79	R:R:V83	2.98	No	No	0	5	6
220	R:R:L241	R:R:T237	2.95	No	No	0	3	4
221	R:R:I62	R:R:I63	2.94	No	No	0	7	3
222	R:R:I314	R:R:M311	2.92	No	No	0	6	6
223	R:R:I64	R:R:K68	2.91	No	No	0	7	4
224	R:R:D179	R:R:T109	2.89	No	Yes	0	4	3
225	R:R:F177	R:R:P173	2.89	No	No	0	4	8
226	R:R:I265	R:R:L315	2.85	No	No	0	8	7
227	R:R:I55	R:R:N89	2.83	No	Yes	0	5	6
228	R:R:G108	R:R:W105	2.81	No	Yes	0	8	9
229	R:R:P299	R:R:Y103	2.78	No	Yes	0	3	4
230	R:R:H104	R:R:V106	2.77	No	No	0	5	3
231	R:R:A181	R:R:F190	2.77	No	Yes	0	2	3
232	R:R:H286	R:R:T287	2.74	No	No	0	2	1
233	L:L:A155	R:R:Y276	2.67	No	Yes	0	9	6
234	R:R:H285	R:R:M289	2.63	No	No	0	5	3
235	R:R:H104	R:R:K186	2.62	No	No	0	5	2
236	R:R:F177	R:R:V176	2.62	No	No	0	4	4
237	R:R:F193	R:R:V220	2.62	Yes	No	0	5	5
238	R:R:R216	R:R:V212	2.62	Yes	No	0	4	3
239	R:R:R224	R:R:V220	2.62	Yes	No	0	5	5
240	R:R:F294	R:R:V293	2.62	Yes	No	0	5	1
241	R:R:A159	R:R:W77	2.59	No	Yes	0	5	7
242	R:R:A84	R:R:W164	2.59	No	Yes	0	8	9
243	R:R:V46	R:R:Y47	2.52	No	Yes	0	5	8
244	R:R:F78	R:R:M75	2.49	Yes	Yes	0	8	8
245	R:R:F318	R:R:L60	2.44	Yes	No	0	6	6
246	R:R:F270	R:R:L271	2.44	No	No	0	6	6
247	R:R:I96	R:R:Y47	2.42	Yes	Yes	0	7	8
248	R:R:I139	R:R:W146	2.35	No	No	0	5	4
249	R:R:G57	R:R:P313	2.03	No	No	0	7	9
250	R:R:C227	R:R:G228	1.96	No	No	0	4	6
251	R:R:A301	R:R:P275	1.87	No	No	0	7	9
252	R:R:G59	R:R:I62	1.76	No	No	0	3	7
253	R:R:C239	R:R:S135	1.72	No	No	0	7	6
254	R:R:G297	R:R:L279	1.71	No	No	0	5	4
255	R:R:A307	R:R:V50	1.7	No	No	0	5	7
256	R:R:C227	R:R:T223	1.69	No	No	0	4	4
257	R:R:C274	R:R:T278	1.69	Yes	No	0	6	5
258	R:R:A110	R:R:T109	1.68	No	Yes	0	3	3
259	R:R:M289	R:R:P290	1.68	No	No	0	3	1
260	R:R:L143	R:R:P144	1.64	No	No	0	6	8
261	R:R:G320	R:R:Q321	1.64	No	No	0	8	5
262	R:R:S48	R:R:V44	1.62	No	No	0	4	5
263	R:R:S215	R:R:V219	1.62	No	No	0	1	3
264	R:R:T223	R:R:V219	1.59	No	No	0	4	3
265	R:R:T237	R:R:V233	1.59	No	No	0	4	5
266	R:R:T264	R:R:V263	1.59	No	No	0	5	4
267	R:R:I96	R:R:S48	1.55	Yes	No	0	7	4
268	R:R:I266	R:R:T237	1.52	No	No	0	8	4
269	R:R:I267	R:R:T268	1.52	No	No	0	5	7
270	R:R:F294	R:R:G291	1.51	Yes	No	0	5	2
271	R:R:K70	R:R:T72	1.5	No	No	0	6	7
272	R:R:L166	R:R:V162	1.49	No	No	0	4	4
273	R:R:L234	R:R:V233	1.49	No	No	0	4	5
274	R:R:L281	R:R:T221	1.47	No	No	0	5	6
275	R:R:I49	R:R:L53	1.43	No	No	0	4	5
276	R:R:L155	R:R:M158	1.41	No	No	0	3	3
277	R:R:C245	R:R:R249	1.39	No	No	0	4	5
278	R:R:L300	R:R:L43	1.38	No	No	0	5	6
279	R:R:L226	R:R:L230	1.38	No	No	0	4	4
280	R:R:A305	R:R:Y276	1.33	No	Yes	0	8	6
281	R:R:N149	R:R:Q148	1.32	No	No	0	4	4
282	R:R:F52	R:R:I55	1.26	No	No	0	5	5
283	R:R:L143	R:R:W146	1.14	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F154	8.5975	4	4	6
2	R:R:Y47	5.7925	4	0	8
3	R:R:M75	5.665	4	7	8
4	R:R:W77	5.005	6	0	7
5	R:R:F78	3.61	4	0	8
6	R:R:D85	7.186	5	0	9
7	R:R:F88	5.185	4	0	8
8	R:R:N89	3.95	4	0	6
9	R:R:I96	2.91	4	6	7
10	R:R:Y103	8.1025	4	0	4
11	R:R:W105	9.00333	6	3	9
12	R:R:F107	10.2825	4	3	8
13	R:R:T109	2.6775	4	0	3
14	R:R:F117	7.812	5	9	5
15	R:R:F124	5.2775	4	0	7
16	R:R:C138	4.275	4	10	8
17	R:R:W164	6.38	4	0	9
18	R:R:R178	10.59	4	0	5
19	R:R:F190	7.7475	4	0	3
20	R:R:N191	6.0975	4	5	5
21	R:R:F193	8.724	5	0	5
22	R:R:R216	3.76	4	0	4
23	R:R:H217	9.536	5	1	4
24	R:R:R224	4.2775	4	0	5
25	R:R:F229	5.116	5	2	9
26	R:R:Y240	7.2725	4	0	9
27	R:R:W273	6.96	6	2	9
28	R:R:C274	4.8575	4	2	6
29	R:R:Y276	5.165	4	0	6
30	R:R:F294	3.7	5	0	5
31	R:R:Y316	6.154	5	8	9
32	R:R:F318	7.725	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:T109	R:R:T180	10.6842	3.14	Yes	No	0	3	4
2	R:R:C112	R:R:T180	11.8395	3.38	No	No	0	9	4
3	R:R:W105	R:R:Y98	17.6716	11.58	Yes	No	0	9	5
4	R:R:E283	R:R:F294	13.0655	3.5	No	Yes	0	4	5
5	R:R:E283	R:R:H217	13.658	7.39	No	Yes	1	4	4
6	R:R:F193	R:R:H217	24.0329	18.1	Yes	Yes	0	5	4
7	L:L:S157	R:R:N191	41.1791	8.94	No	Yes	5	5	5
8	L:L:F156	R:R:H95	12.0034	9.05	No	No	0	9	6
9	R:R:H95	R:R:Y98	13.1848	6.53	No	No	0	6	5
10	R:R:F193	R:R:V220	32.1644	2.62	Yes	No	0	5	5
11	R:R:R224	R:R:V220	32.8054	2.62	Yes	No	0	5	5
12	R:R:F124	R:R:R224	85.1942	4.28	Yes	Yes	0	7	5
13	R:R:F124	R:R:M123	88.3245	6.22	Yes	No	0	7	8
14	R:R:M123	R:R:W273	88.7419	4.65	No	Yes	0	8	9
15	R:R:V127	R:R:W273	95.7852	3.68	No	Yes	0	7	9
16	R:R:P232	R:R:V127	96.0386	3.53	No	No	0	9	7
17	R:R:P232	R:R:T131	96.0237	3.5	No	No	0	9	7
18	R:R:I236	R:R:T131	97.1939	3.04	No	No	0	8	7
19	R:R:I236	R:R:S134	97.4025	4.64	No	No	0	8	9
20	R:R:S134	R:R:Y240	100	6.36	No	Yes	0	9	9
21	R:R:R137	R:R:Y240	54.0993	8.23	No	Yes	0	9	9
22	R:R:R137	R:R:Y316	43.7691	6.17	No	Yes	8	9	9
23	R:R:L130	R:R:Y316	65.1785	8.21	No	Yes	0	8	9
24	R:R:L130	R:R:N312	63.9636	4.12	No	No	0	8	9
25	R:R:D85	R:R:N312	62.7189	6.73	Yes	No	0	9	9
26	R:R:D85	R:R:S309	40.2065	5.89	Yes	No	0	9	9
27	R:R:N89	R:R:S309	38.7531	5.96	Yes	No	0	6	9
28	R:R:F88	R:R:N89	31.3744	3.62	Yes	Yes	0	8	6
29	R:R:F88	R:R:I306	25.3373	3.77	Yes	No	0	8	7
30	R:R:I306	R:R:L92	19.1809	4.28	No	No	0	7	8
31	R:R:I96	R:R:L92	14.4183	4.28	Yes	No	6	7	8
32	R:R:I265	R:R:Y240	46.0088	6.04	No	Yes	0	8	9
33	R:R:I265	R:R:Y316	44.8014	8.46	No	Yes	0	8	9
34	R:R:D85	R:R:N58	23.8093	13.46	Yes	No	0	9	9
35	R:R:N58	R:R:P313	22.274	9.77	No	No	0	9	9
36	R:R:F78	R:R:Y316	33.2526	3.09	Yes	Yes	0	8	9
37	R:R:F78	R:R:M75	25.9484	2.49	Yes	Yes	0	8	8
38	R:R:D322	R:R:M75	19.9188	4.16	No	Yes	7	6	8
39	R:R:D322	R:R:I64	18.5846	4.2	No	No	0	6	7
40	R:R:I64	R:R:K68	17.2095	2.91	No	No	0	7	4
41	R:R:F67	R:R:K68	12.6071	7.44	No	No	0	5	4
42	R:R:I133	R:R:R137	10.0507	5.01	No	No	8	9	9
43	R:R:I133	R:R:W77	12.8047	4.7	No	Yes	0	9	7
44	R:R:I120	R:R:R224	19.7622	6.26	No	Yes	0	4	5
45	R:R:I120	R:R:S171	18.6592	3.1	No	No	0	4	7
46	R:R:F107	R:R:W105	10.5612	23.05	Yes	Yes	3	8	9
47	R:R:C189	R:R:W105	29.4477	5.22	No	Yes	3	9	9
48	R:R:C189	R:R:R178	41.6487	6.96	No	Yes	0	9	5
49	R:R:C239	R:R:S134	21.7709	5.16	No	No	0	7	9
50	R:R:C138	R:R:C239	11.7985	7.28	Yes	No	0	8	7
51	R:R:I262	R:R:Y240	14.0083	8.46	No	Yes	0	8	9
52	R:R:I262	R:R:V244	12.95	3.07	No	No	0	8	5
53	R:R:F259	R:R:V244	11.8022	3.93	No	No	0	7	5
54	R:R:F318	R:R:P313	12.9053	4.33	Yes	No	0	6	9
55	R:R:N191	R:R:R178	44.2424	8.44	Yes	Yes	0	5	5
56	R:R:C112	R:R:C189	11.3326	7.28	No	No	3	9	9
57	L:L:S157	R:R:R224	42.6437	3.95	No	Yes	0	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y149	R:R:F294	7.22	4	No	Yes	5	5	0	1
L:L:F150	R:R:F190	18.22	0	No	Yes	4	3	0	1
L:L:P151	R:R:H217	7.63	1	No	Yes	9	4	0	1
L:L:P151	R:R:E283	4.72	1	No	No	9	4	0	1
L:L:P151	R:R:H286	7.63	1	No	No	9	2	0	1
L:L:G152	R:R:N191	3.39	5	No	Yes	9	5	0	1
L:L:F154	R:R:Y103	12.38	4	Yes	Yes	6	4	0	1
L:L:F154	R:R:S295	5.28	4	Yes	No	6	4	0	1
L:L:A155	R:R:L298	3.15	0	No	No	9	4	0	1
L:L:F156	R:R:H95	9.05	0	No	No	9	6	0	1
L:L:F156	R:R:Y276	6.19	0	No	Yes	9	6	0	1
L:L:F156	R:R:T302	3.89	0	No	No	9	6	0	1
L:L:S157	R:R:N191	8.94	5	No	Yes	5	5	0	1
L:L:S157	R:R:R224	3.95	5	No	Yes	5	5	0	1
R:R:H95	R:R:Y98	6.53	0	No	No	6	5	1	2
R:R:Y103	R:R:Y98	11.91	0	Yes	No	4	5	1	2
R:R:A99	R:R:Y103	5.34	0	No	Yes	5	4	2	1
R:R:I120	R:R:R224	6.26	0	No	Yes	4	5	2	1
R:R:F124	R:R:R224	4.28	0	Yes	Yes	7	5	2	1
R:R:N191	R:R:R178	8.44	5	Yes	Yes	5	5	1	2
R:R:F190	R:R:S188	3.96	0	Yes	No	3	4	1	2
R:R:F190	R:R:N192	6.04	0	Yes	No	3	2	1	2
R:R:F193	R:R:N191	3.62	0	Yes	Yes	5	5	2	1
R:R:F193	R:R:H217	18.1	0	Yes	Yes	5	4	2	1
R:R:H217	R:R:T221	6.85	1	Yes	No	4	6	1	2
R:R:E283	R:R:H217	7.39	1	No	Yes	4	4	1	1
R:R:H217	R:R:L284	7.71	1	Yes	No	4	5	1	2
R:R:N280	R:R:Y276	10.47	0	No	Yes	5	6	2	1
R:R:L279	R:R:L298	4.15	0	No	No	4	4	2	1
R:R:F294	R:R:L282	3.65	0	Yes	No	5	5	1	2
R:R:E283	R:R:F294	3.5	1	No	Yes	4	5	1	1
R:R:P299	R:R:Y103	2.78	0	No	Yes	3	4	2	1
R:R:A181	R:R:F190	2.77	0	No	Yes	2	3	2	1
R:R:H286	R:R:T287	2.74	0	No	No	2	1	1	2
L:L:A155	R:R:Y276	2.67	0	No	Yes	9	6	0	1
R:R:F193	R:R:V220	2.62	0	Yes	No	5	5	2	2
R:R:R224	R:R:V220	2.62	0	Yes	No	5	5	1	2
R:R:F294	R:R:V293	2.62	0	Yes	No	5	1	1	2
R:R:F294	R:R:G291	1.51	0	Yes	No	5	2	1	2
R:R:A305	R:R:Y276	1.33	0	No	Yes	8	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8SG1_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.04
Number of Linked Nodes	268
Number of Links	283
Number of Hubs	32
Number of Links mediated by Hubs	128
Number of Communities	10
Number of Nodes involved in Communities	38
Number of Links involved in Communities	42

Path Summary
Number Of Nodes in MetaPath	58
Number Of Links MetaPath	57
Number of Shortest Paths	45500
Length Of Smallest Path	3
Average Path Length	17.1835
Length of Longest Path	38
Minimum Path Strength	1.39
Average Path Strength	5.55886
Maximum Path Strength	17.315
Minimum Path Correlation	0.7
Average Path Correlation	0.925789
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	44.9791
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.3579
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	Chemerin-9
UniProt	Q99969
Sequence	>8SG1_nogp_Chain_L Y F P G Q F A F S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q99788
Sequence	>8SG1_nogp_Chain_R A R V T R I F L V V V Y S I V C F L G I L G N G L V I I I A T F K M K K T V N M V W F L N L A V A D F L F N V F L P I H I T Y A A M D Y H W V F G T A M C K I S N F L L I H N M F T S V F L L T I I S S D R C I S V L L P V W S Q N H R S V R L A Y M A C M V I W V L A F F L S S P S L V F R D T A N L H G K I S C F N N F S L S D P V G Y S R H M V V T V T R F L C G F L V P V L I I T A C Y L T I V C K L Q R N R L A K T K K P F K I I V T I I I T F F L C W C P Y H T L N L L E L H H T A M P G S V F S L G L P L A T A L A I A N S C M N P I L Y V F M G Q D F K K F K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7YKD	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/β1/γ2	2.81	2023-04-19	doi.org/10.1073/pnas.2214324120
	7YKD (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-		2.81	2023-04-19	doi.org/10.1073/pnas.2214324120
	8SG1	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/β1/γ2	2.94	2023-11-01	doi.org/10.1371/journal.pbio.3002188
	8SG1 (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-		2.94	2023-11-01	doi.org/10.1371/journal.pbio.3002188
	8ZJG	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-	Gi1/β1/γ2	3.18	2025-01-22	doi.org/10.1038/s42003-024-07228-9
	8ZJG (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-		3.18	2025-01-22	doi.org/10.1038/s42003-024-07228-9
	9L3W	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-	Gi1/β1/γ2	3.5	2025-03-12	doi.org/10.1093/procel/pwae073
	9L3W (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-		3.5	2025-03-12	doi.org/10.1093/procel/pwae073
	9L3Z	A	Protein	Chemerin	CML1	Homo sapiens	LRH7-C2	-	-	3.9	2025-03-12	doi.org/10.1093/procel/pwae073

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8SG1_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.