psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:Q153	L:L:Y149	12.4	No	No	4	0	0
2	L:L:F154	L:L:Y149	6.19	Yes	No	4	0	0
3	L:L:Y149	R:R:F294	7.22	No	Yes	0	0	5
4	L:L:F150	R:R:F190	18.22	No	Yes	0	0	3
5	L:L:P151	R:R:H217	7.63	No	Yes	1	0	4
6	L:L:P151	R:R:E283	4.72	No	No	1	0	4
7	L:L:P151	R:R:H286	7.63	No	No	0	0	2
8	L:L:G152	L:L:S157	3.71	No	No	5	0	0
9	L:L:G152	R:R:N191	3.39	No	Yes	5	0	5
10	L:L:F154	L:L:Q153	10.54	Yes	No	4	0	0
11	L:L:F154	R:R:Y103	12.38	Yes	Yes	0	0	4
12	L:L:F154	R:R:S295	5.28	Yes	No	0	0	4
13	L:L:A155	R:R:L298	3.15	No	No	0	0	4
14	L:L:F156	R:R:H95	9.05	No	No	0	0	6
15	L:L:F156	R:R:Y276	6.19	No	Yes	0	0	6
16	L:L:F156	R:R:T302	3.89	No	No	0	0	6
17	L:L:S157	R:R:N191	8.94	No	Yes	5	0	5
18	L:L:S157	R:R:R224	3.95	No	Yes	0	0	5
19	R:R:R37	R:R:R40	6.4	No	No	0	3	4
20	R:R:L43	R:R:Y47	12.89	No	Yes	0	6	8
21	R:R:A100	R:R:V44	3.39	No	No	0	5	5
22	R:R:I49	R:R:V45	3.07	No	No	0	4	5
23	R:R:A303	R:R:Y47	5.34	No	Yes	0	5	8
24	R:R:I306	R:R:V50	4.61	No	No	0	7	7
25	R:R:C310	R:R:V50	3.42	No	No	0	8	7
26	R:R:C51	R:R:P93	3.77	No	No	0	6	8
27	R:R:L53	R:R:L56	4.15	No	No	0	5	5
28	R:R:G54	R:R:N89	3.39	No	Yes	0	8	6
29	R:R:F86	R:R:I55	3.77	No	No	0	8	5
30	R:R:G57	R:R:L56	5.13	No	No	0	7	5
31	R:R:D85	R:R:N58	13.46	Yes	No	0	9	9
32	R:R:N58	R:R:P313	9.77	No	No	0	9	9
33	R:R:A82	R:R:V61	3.39	No	No	0	8	9
34	R:R:V317	R:R:V61	8.02	No	No	0	7	9
35	R:R:I62	R:R:V83	3.07	No	No	0	7	6
36	R:R:F67	R:R:I63	5.02	No	No	0	5	3
37	R:R:D322	R:R:I64	4.2	No	No	0	6	7
38	R:R:A65	R:R:L79	3.15	No	No	0	6	5
39	R:R:F67	R:R:T66	3.89	No	No	0	5	4
40	R:R:F67	R:R:K68	7.44	No	No	0	5	4
41	R:R:F326	R:R:K68	9.93	No	No	0	4	4
42	R:R:M69	R:R:M75	13	No	Yes	7	5	8
43	R:R:D322	R:R:M69	13.86	No	No	7	6	5
44	R:R:V73	R:R:W77	3.68	No	Yes	0	6	7
45	R:R:F78	R:R:N74	3.62	Yes	No	0	8	8
46	R:R:D322	R:R:M75	4.16	No	Yes	7	6	8
47	R:R:A156	R:R:V76	5.09	No	No	0	7	6
48	R:R:V76	R:R:Y157	8.83	No	No	0	6	3
49	R:R:I132	R:R:W77	9.4	No	Yes	0	6	7
50	R:R:I133	R:R:W77	4.7	No	Yes	0	9	7
51	R:R:D136	R:R:W77	4.47	No	Yes	0	8	7
52	R:R:A156	R:R:W77	5.19	No	Yes	0	7	7
53	R:R:F78	R:R:Y316	3.09	Yes	Yes	0	8	9
54	R:R:F78	R:R:V317	5.24	Yes	No	0	8	7
55	R:R:C160	R:R:N80	11.02	No	No	0	7	9
56	R:R:N80	R:R:W164	3.39	No	Yes	0	9	9
57	R:R:D85	R:R:L81	5.43	Yes	No	0	9	9
58	R:R:L129	R:R:L81	4.15	No	No	0	8	9
59	R:R:D85	R:R:S126	4.42	Yes	No	0	9	9
60	R:R:D85	R:R:S309	5.89	Yes	No	0	9	9
61	R:R:D85	R:R:N312	6.73	Yes	No	0	9	9
62	R:R:L87	R:R:N122	5.49	No	No	0	7	8
63	R:R:F88	R:R:N89	3.62	Yes	Yes	0	8	6
64	R:R:F88	R:R:L119	7.31	Yes	No	0	8	6
65	R:R:F88	R:R:N122	6.04	Yes	No	0	8	8
66	R:R:F88	R:R:I306	3.77	Yes	No	0	8	7
67	R:R:N89	R:R:S309	5.96	Yes	No	0	6	9
68	R:R:F91	R:R:V90	7.87	No	No	0	6	5
69	R:R:F91	R:R:L118	7.31	No	No	0	6	5
70	R:R:L92	R:R:P93	3.28	No	No	6	8	8
71	R:R:I96	R:R:L92	4.28	Yes	No	6	7	8
72	R:R:I306	R:R:L92	4.28	No	No	0	7	8
73	R:R:I96	R:R:P93	3.39	Yes	No	6	7	8
74	R:R:I94	R:R:W105	3.52	No	Yes	3	6	9
75	R:R:F107	R:R:I94	5.02	Yes	No	3	8	6
76	R:R:I94	R:R:M111	4.37	No	No	0	6	6
77	R:R:H95	R:R:Y98	6.53	No	No	0	6	5
78	R:R:F107	R:R:T97	5.19	Yes	No	0	8	4
79	R:R:Y103	R:R:Y98	11.91	Yes	No	0	4	5
80	R:R:W105	R:R:Y98	11.58	Yes	No	0	9	5
81	R:R:A99	R:R:Y103	5.34	No	Yes	0	5	4
82	R:R:M101	R:R:V106	4.56	No	No	0	4	3
83	R:R:D102	R:R:K186	11.06	No	No	0	4	2
84	R:R:H104	R:R:I187	11.93	No	No	0	5	5
85	R:R:F107	R:R:W105	23.05	Yes	Yes	3	8	9
86	R:R:C112	R:R:W105	7.84	No	Yes	3	9	9
87	R:R:C189	R:R:W105	5.22	No	Yes	3	9	9
88	R:R:F107	R:R:V106	7.87	Yes	No	0	8	3
89	R:R:T109	R:R:T180	3.14	Yes	No	0	3	4
90	R:R:M111	R:R:S115	3.07	No	No	0	6	5
91	R:R:C112	R:R:T180	3.38	No	No	0	9	4
92	R:R:C112	R:R:C189	7.28	No	No	3	9	9
93	R:R:F117	R:R:I114	5.02	Yes	No	9	5	4
94	R:R:I114	R:R:L118	5.71	No	No	9	4	5
95	R:R:N116	R:R:R178	21.69	No	Yes	0	6	5
96	R:R:F117	R:R:L118	4.87	Yes	No	9	5	5
97	R:R:F117	R:R:F168	4.29	Yes	No	0	5	3
98	R:R:F117	R:R:S171	6.61	Yes	No	0	5	7
99	R:R:F117	R:R:L175	18.27	Yes	No	0	5	4
100	R:R:I120	R:R:S171	3.1	No	No	0	4	7
101	R:R:I120	R:R:R224	6.26	No	Yes	0	4	5
102	R:R:H121	R:R:W164	7.41	No	Yes	0	5	9
103	R:R:F168	R:R:H121	3.39	No	No	0	3	5
104	R:R:H121	R:R:S171	5.58	No	No	0	5	7
105	R:R:F124	R:R:M123	6.22	Yes	No	0	7	8
106	R:R:M123	R:R:W273	4.65	No	Yes	0	8	9
107	R:R:F124	R:R:L170	6.09	Yes	No	0	7	5
108	R:R:F124	R:R:R224	4.28	Yes	Yes	0	7	5
109	R:R:F124	R:R:G228	4.52	Yes	No	0	7	6
110	R:R:T125	R:R:W164	12.13	No	Yes	0	7	9
111	R:R:A167	R:R:T125	3.36	No	No	0	8	7
112	R:R:P232	R:R:V127	3.53	No	No	0	9	7
113	R:R:V127	R:R:W273	3.68	No	Yes	0	7	9
114	R:R:F128	R:R:I163	5.02	No	No	0	6	7
115	R:R:I163	R:R:L129	4.28	No	No	0	7	8
116	R:R:L130	R:R:N312	4.12	No	No	0	8	9
117	R:R:L130	R:R:Y316	8.21	No	Yes	0	8	9
118	R:R:P232	R:R:T131	3.5	No	No	0	9	7
119	R:R:I235	R:R:T131	6.08	No	No	0	7	7
120	R:R:I236	R:R:T131	3.04	No	No	0	8	7
121	R:R:I132	R:R:I163	4.42	No	No	0	6	7
122	R:R:I133	R:R:R137	5.01	No	No	8	9	9
123	R:R:I133	R:R:Y316	4.84	No	Yes	8	9	9
124	R:R:I236	R:R:S134	4.64	No	No	0	8	9
125	R:R:C239	R:R:S134	5.16	No	No	0	7	9
126	R:R:S134	R:R:Y240	6.36	No	Yes	0	9	9
127	R:R:I139	R:R:S135	3.1	No	No	0	5	6
128	R:R:D136	R:R:R151	11.91	No	No	0	8	6
129	R:R:R137	R:R:Y240	8.23	No	Yes	0	9	9
130	R:R:R137	R:R:Y316	6.17	No	Yes	8	9	9
131	R:R:C138	R:R:L142	3.17	Yes	No	10	8	7
132	R:R:C138	R:R:C239	7.28	Yes	No	0	8	7
133	R:R:C138	R:R:T242	3.38	Yes	No	10	8	4
134	R:R:C138	R:R:I243	3.27	Yes	No	0	8	8
135	R:R:S140	R:R:S147	3.26	No	No	0	7	4
136	R:R:I243	R:R:V141	3.07	No	No	0	8	8
137	R:R:L142	R:R:T242	4.42	No	No	10	7	4
138	R:R:K246	R:R:L142	5.64	No	No	0	5	7
139	R:R:H150	R:R:W146	21.16	No	No	0	4	4
140	R:R:R151	R:R:S147	3.95	No	No	0	6	4
141	R:R:H150	R:R:N149	3.83	No	No	0	4	4
142	R:R:R154	R:R:S152	3.95	No	No	0	5	6
143	R:R:L155	R:R:S152	4.5	No	No	0	3	6
144	R:R:V153	R:R:Y157	5.05	No	No	0	2	3
145	R:R:P173	R:R:S172	3.56	No	No	0	8	4
146	R:R:R178	R:R:S174	5.27	Yes	No	0	5	5
147	R:R:F177	R:R:F193	15	No	Yes	0	4	5
148	R:R:C189	R:R:R178	6.96	No	Yes	0	9	5
149	R:R:N191	R:R:R178	8.44	Yes	Yes	0	5	5
150	R:R:D179	R:R:N192	10.77	No	No	0	4	2
151	R:R:I187	R:R:N182	8.5	No	No	0	5	1
152	R:R:F190	R:R:S188	3.96	Yes	No	0	3	4
153	R:R:F190	R:R:N192	6.04	Yes	No	0	3	2
154	R:R:F193	R:R:N191	3.62	Yes	Yes	0	5	5
155	R:R:F193	R:R:R216	4.28	Yes	Yes	0	5	4
156	R:R:F193	R:R:H217	18.1	Yes	Yes	0	5	4
157	R:R:S194	R:R:V212	4.85	No	No	0	3	3
158	R:R:L195	R:R:R216	3.64	No	Yes	0	4	4
159	R:R:D210	R:R:P211	11.27	No	No	0	4	2
160	R:R:D210	R:R:V212	5.84	No	No	0	4	3
161	R:R:G213	R:R:R216	4.5	No	Yes	0	3	4
162	R:R:M218	R:R:Y214	3.59	No	No	1	1	1
163	R:R:L284	R:R:Y214	15.24	No	No	1	5	1
164	R:R:H217	R:R:T221	6.85	Yes	No	0	4	6
165	R:R:E283	R:R:H217	7.39	No	Yes	1	4	4
166	R:R:H217	R:R:L284	7.71	Yes	No	1	4	5
167	R:R:M218	R:R:V222	3.04	No	No	0	1	4
168	R:R:L284	R:R:M218	4.24	No	No	1	5	1
169	R:R:F225	R:R:L226	3.65	No	No	0	5	4
170	R:R:F225	R:R:H277	3.39	No	No	0	5	8
171	R:R:F229	R:R:F269	5.36	Yes	No	2	9	9
172	R:R:F229	R:R:F270	5.36	Yes	No	2	9	6
173	R:R:F229	R:R:W273	5.01	Yes	Yes	2	9	9
174	R:R:C274	R:R:F229	4.19	Yes	Yes	2	6	9
175	R:R:F229	R:R:H277	5.66	Yes	No	2	9	8
176	R:R:P232	R:R:V231	3.53	No	No	0	9	6
177	R:R:I235	R:R:V231	3.07	No	No	0	7	6
178	R:R:F269	R:R:V233	5.24	No	No	0	9	5
179	R:R:I262	R:R:Y240	8.46	No	Yes	0	8	9
180	R:R:I265	R:R:Y240	6.04	No	Yes	0	8	9
181	R:R:F259	R:R:V244	3.93	No	No	0	7	5
182	R:R:I262	R:R:V244	3.07	No	No	0	8	5
183	R:R:K246	R:R:R249	8.66	No	No	0	5	5
184	R:R:A253	R:R:L247	4.73	No	No	0	5	8
185	R:R:L247	R:R:P258	3.28	No	No	0	8	7
186	R:R:F259	R:R:L247	7.31	No	No	0	7	8
187	R:R:N250	R:R:R249	7.23	No	No	0	5	5
188	R:R:L252	R:R:N250	5.49	No	No	0	3	5
189	R:R:F259	R:R:K256	7.44	No	No	0	7	5
190	R:R:K256	R:R:K260	11.49	No	No	0	5	5
191	R:R:K257	R:R:P258	3.35	No	No	0	7	7
192	R:R:K257	R:R:M319	5.76	No	No	0	7	6
193	R:R:I261	R:R:M319	7.29	No	No	0	8	6
194	R:R:L315	R:R:T264	5.9	No	No	0	7	5
195	R:R:I265	R:R:Y316	8.46	No	Yes	0	8	9
196	R:R:M311	R:R:T268	6.02	No	No	0	6	7
197	R:R:F269	R:R:W273	13.03	No	Yes	2	9	9
198	R:R:C274	R:R:F270	9.78	Yes	No	2	6	6
199	R:R:C272	R:R:N308	3.15	No	No	0	9	9
200	R:R:H277	R:R:W273	6.35	No	Yes	2	8	9
201	R:R:N308	R:R:W273	9.04	No	Yes	0	9	9
202	R:R:C274	R:R:P275	3.77	Yes	No	0	6	9
203	R:R:L304	R:R:P275	3.28	No	No	0	7	9
204	R:R:N280	R:R:Y276	10.47	No	Yes	0	5	6
205	R:R:L279	R:R:L298	4.15	No	No	0	4	4
206	R:R:L282	R:R:M289	4.24	No	No	0	5	3
207	R:R:F294	R:R:L282	3.65	Yes	No	0	5	5
208	R:R:E283	R:R:F294	3.5	No	Yes	0	4	5
209	R:R:P290	R:R:S292	3.56	No	No	0	1	4
210	R:R:G297	R:R:L296	3.42	No	No	0	5	1
211	R:R:F318	R:R:P313	4.33	Yes	No	0	6	9
212	R:R:F318	R:R:I314	3.77	Yes	No	0	6	6
213	R:R:F318	R:R:F323	20.36	Yes	No	0	6	8
214	R:R:F323	R:R:K327	6.2	No	No	0	8	6
215	R:R:F326	R:R:K325	6.2	No	No	0	4	5
216	R:R:M75	R:R:T72	3.01	Yes	No	0	8	7
217	R:R:K113	R:R:T109	3	No	Yes	0	7	3
218	R:R:K257	R:R:T255	3	No	No	0	7	6
219	R:R:L79	R:R:V83	2.98	No	No	0	5	6
220	R:R:L241	R:R:T237	2.95	No	No	0	3	4
221	R:R:I62	R:R:I63	2.94	No	No	0	7	3
222	R:R:I314	R:R:M311	2.92	No	No	0	6	6
223	R:R:I64	R:R:K68	2.91	No	No	0	7	4
224	R:R:D179	R:R:T109	2.89	No	Yes	0	4	3
225	R:R:F177	R:R:P173	2.89	No	No	0	4	8
226	R:R:I265	R:R:L315	2.85	No	No	0	8	7
227	R:R:I55	R:R:N89	2.83	No	Yes	0	5	6
228	R:R:G108	R:R:W105	2.81	No	Yes	0	8	9
229	R:R:P299	R:R:Y103	2.78	No	Yes	0	3	4
230	R:R:H104	R:R:V106	2.77	No	No	0	5	3
231	R:R:A181	R:R:F190	2.77	No	Yes	0	2	3
232	R:R:H286	R:R:T287	2.74	No	No	0	2	1
233	L:L:A155	R:R:Y276	2.67	No	Yes	0	0	6
234	R:R:H285	R:R:M289	2.63	No	No	0	5	3
235	R:R:H104	R:R:K186	2.62	No	No	0	5	2
236	R:R:F177	R:R:V176	2.62	No	No	0	4	4
237	R:R:F193	R:R:V220	2.62	Yes	No	0	5	5
238	R:R:R216	R:R:V212	2.62	Yes	No	0	4	3
239	R:R:R224	R:R:V220	2.62	Yes	No	0	5	5
240	R:R:F294	R:R:V293	2.62	Yes	No	0	5	1
241	R:R:A159	R:R:W77	2.59	No	Yes	0	5	7
242	R:R:A84	R:R:W164	2.59	No	Yes	0	8	9
243	R:R:V46	R:R:Y47	2.52	No	Yes	0	5	8
244	R:R:F78	R:R:M75	2.49	Yes	Yes	0	8	8
245	R:R:F318	R:R:L60	2.44	Yes	No	0	6	6
246	R:R:F270	R:R:L271	2.44	No	No	0	6	6
247	R:R:I96	R:R:Y47	2.42	Yes	Yes	0	7	8
248	R:R:I139	R:R:W146	2.35	No	No	0	5	4
249	R:R:G57	R:R:P313	2.03	No	No	0	7	9
250	R:R:C227	R:R:G228	1.96	No	No	0	4	6
251	R:R:A301	R:R:P275	1.87	No	No	0	7	9
252	R:R:G59	R:R:I62	1.76	No	No	0	3	7
253	R:R:C239	R:R:S135	1.72	No	No	0	7	6
254	R:R:G297	R:R:L279	1.71	No	No	0	5	4
255	R:R:A307	R:R:V50	1.7	No	No	0	5	7
256	R:R:C227	R:R:T223	1.69	No	No	0	4	4
257	R:R:C274	R:R:T278	1.69	Yes	No	0	6	5
258	R:R:A110	R:R:T109	1.68	No	Yes	0	3	3
259	R:R:M289	R:R:P290	1.68	No	No	0	3	1
260	R:R:L143	R:R:P144	1.64	No	No	0	6	8
261	R:R:G320	R:R:Q321	1.64	No	No	0	8	5
262	R:R:S48	R:R:V44	1.62	No	No	0	4	5
263	R:R:S215	R:R:V219	1.62	No	No	0	1	3
264	R:R:T223	R:R:V219	1.59	No	No	0	4	3
265	R:R:T237	R:R:V233	1.59	No	No	0	4	5
266	R:R:T264	R:R:V263	1.59	No	No	0	5	4
267	R:R:I96	R:R:S48	1.55	Yes	No	0	7	4
268	R:R:I266	R:R:T237	1.52	No	No	0	8	4
269	R:R:I267	R:R:T268	1.52	No	No	0	5	7
270	R:R:F294	R:R:G291	1.51	Yes	No	0	5	2
271	R:R:K70	R:R:T72	1.5	No	No	0	6	7
272	R:R:L166	R:R:V162	1.49	No	No	0	4	4
273	R:R:L234	R:R:V233	1.49	No	No	0	4	5
274	R:R:L281	R:R:T221	1.47	No	No	0	5	6
275	R:R:I49	R:R:L53	1.43	No	No	0	4	5
276	R:R:L155	R:R:M158	1.41	No	No	0	3	3
277	R:R:C245	R:R:R249	1.39	No	No	0	4	5
278	R:R:L300	R:R:L43	1.38	No	No	0	5	6
279	R:R:L226	R:R:L230	1.38	No	No	0	4	4
280	R:R:A305	R:R:Y276	1.33	No	Yes	0	8	6
281	R:R:N149	R:R:Q148	1.32	No	No	0	4	4
282	R:R:F52	R:R:I55	1.26	No	No	0	5	5
283	R:R:L143	R:R:W146	1.14	No	No	0	6	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F154	8.5975	4	4	0
2	R:R:Y47	5.7925	4	0	8
3	R:R:M75	5.665	4	7	8
4	R:R:W77	5.005	6	0	7
5	R:R:F78	3.61	4	0	8
6	R:R:D85	7.186	5	0	9
7	R:R:F88	5.185	4	0	8
8	R:R:N89	3.95	4	0	6
9	R:R:I96	2.91	4	6	7
10	R:R:Y103	8.1025	4	0	4
11	R:R:W105	9.00333	6	3	9
12	R:R:F107	10.2825	4	3	8
13	R:R:T109	2.6775	4	0	3
14	R:R:F117	7.812	5	9	5
15	R:R:F124	5.2775	4	0	7
16	R:R:C138	4.275	4	10	8
17	R:R:W164	6.38	4	0	9
18	R:R:R178	10.59	4	0	5
19	R:R:F190	7.7475	4	0	3
20	R:R:N191	6.0975	4	5	5
21	R:R:F193	8.724	5	0	5
22	R:R:R216	3.76	4	0	4
23	R:R:H217	9.536	5	1	4
24	R:R:R224	4.2775	4	0	5
25	R:R:F229	5.116	5	2	9
26	R:R:Y240	7.2725	4	0	9
27	R:R:W273	6.96	6	2	9
28	R:R:C274	4.8575	4	2	6
29	R:R:Y276	5.165	4	0	6
30	R:R:F294	3.7	5	0	5
31	R:R:Y316	6.154	5	8	9
32	R:R:F318	7.725	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:T109	R:R:T180	10.6842	3.14	Yes	No	0	3	4
2	R:R:C112	R:R:T180	11.8395	3.38	No	No	0	9	4
3	R:R:W105	R:R:Y98	17.6716	11.58	Yes	No	0	9	5
4	R:R:E283	R:R:F294	13.0655	3.5	No	Yes	0	4	5
5	R:R:E283	R:R:H217	13.658	7.39	No	Yes	1	4	4
6	R:R:F193	R:R:H217	24.0329	18.1	Yes	Yes	0	5	4
7	L:L:S157	R:R:N191	41.1791	8.94	No	Yes	5	0	5
8	L:L:F156	R:R:H95	12.0034	9.05	No	No	0	0	6
9	R:R:H95	R:R:Y98	13.1848	6.53	No	No	0	6	5
10	R:R:F193	R:R:V220	32.1644	2.62	Yes	No	0	5	5
11	R:R:R224	R:R:V220	32.8054	2.62	Yes	No	0	5	5
12	R:R:F124	R:R:R224	85.1942	4.28	Yes	Yes	0	7	5
13	R:R:F124	R:R:M123	88.3245	6.22	Yes	No	0	7	8
14	R:R:M123	R:R:W273	88.7419	4.65	No	Yes	0	8	9
15	R:R:V127	R:R:W273	95.7852	3.68	No	Yes	0	7	9
16	R:R:P232	R:R:V127	96.0386	3.53	No	No	0	9	7
17	R:R:P232	R:R:T131	96.0237	3.5	No	No	0	9	7
18	R:R:I236	R:R:T131	97.1939	3.04	No	No	0	8	7
19	R:R:I236	R:R:S134	97.4025	4.64	No	No	0	8	9
20	R:R:S134	R:R:Y240	100	6.36	No	Yes	0	9	9
21	R:R:R137	R:R:Y240	54.0993	8.23	No	Yes	0	9	9
22	R:R:R137	R:R:Y316	43.7691	6.17	No	Yes	8	9	9
23	R:R:L130	R:R:Y316	65.1785	8.21	No	Yes	0	8	9
24	R:R:L130	R:R:N312	63.9636	4.12	No	No	0	8	9
25	R:R:D85	R:R:N312	62.7189	6.73	Yes	No	0	9	9
26	R:R:D85	R:R:S309	40.2065	5.89	Yes	No	0	9	9
27	R:R:N89	R:R:S309	38.7531	5.96	Yes	No	0	6	9
28	R:R:F88	R:R:N89	31.3744	3.62	Yes	Yes	0	8	6
29	R:R:F88	R:R:I306	25.3373	3.77	Yes	No	0	8	7
30	R:R:I306	R:R:L92	19.1809	4.28	No	No	0	7	8
31	R:R:I96	R:R:L92	14.4183	4.28	Yes	No	6	7	8
32	R:R:I265	R:R:Y240	46.0088	6.04	No	Yes	0	8	9
33	R:R:I265	R:R:Y316	44.8014	8.46	No	Yes	0	8	9
34	R:R:D85	R:R:N58	23.8093	13.46	Yes	No	0	9	9
35	R:R:N58	R:R:P313	22.274	9.77	No	No	0	9	9
36	R:R:F78	R:R:Y316	33.2526	3.09	Yes	Yes	0	8	9
37	R:R:F78	R:R:M75	25.9484	2.49	Yes	Yes	0	8	8
38	R:R:D322	R:R:M75	19.9188	4.16	No	Yes	7	6	8
39	R:R:D322	R:R:I64	18.5846	4.2	No	No	0	6	7
40	R:R:I64	R:R:K68	17.2095	2.91	No	No	0	7	4
41	R:R:F67	R:R:K68	12.6071	7.44	No	No	0	5	4
42	R:R:I133	R:R:R137	10.0507	5.01	No	No	8	9	9
43	R:R:I133	R:R:W77	12.8047	4.7	No	Yes	0	9	7
44	R:R:I120	R:R:R224	19.7622	6.26	No	Yes	0	4	5
45	R:R:I120	R:R:S171	18.6592	3.1	No	No	0	4	7
46	R:R:F107	R:R:W105	10.5612	23.05	Yes	Yes	3	8	9
47	R:R:C189	R:R:W105	29.4477	5.22	No	Yes	3	9	9
48	R:R:C189	R:R:R178	41.6487	6.96	No	Yes	0	9	5
49	R:R:C239	R:R:S134	21.7709	5.16	No	No	0	7	9
50	R:R:C138	R:R:C239	11.7985	7.28	Yes	No	0	8	7
51	R:R:I262	R:R:Y240	14.0083	8.46	No	Yes	0	8	9
52	R:R:I262	R:R:V244	12.95	3.07	No	No	0	8	5
53	R:R:F259	R:R:V244	11.8022	3.93	No	No	0	7	5
54	R:R:F318	R:R:P313	12.9053	4.33	Yes	No	0	6	9
55	R:R:N191	R:R:R178	44.2424	8.44	Yes	Yes	0	5	5
56	R:R:C112	R:R:C189	11.3326	7.28	No	No	3	9	9
57	L:L:S157	R:R:R224	42.6437	3.95	No	Yes	0	0	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y149	R:R:F294	7.22	4	No	Yes	0	5	0	1
L:L:F150	R:R:F190	18.22	0	No	Yes	0	3	0	1
L:L:P151	R:R:H217	7.63	1	No	Yes	0	4	0	1
L:L:P151	R:R:E283	4.72	1	No	No	0	4	0	1
L:L:P151	R:R:H286	7.63	1	No	No	0	2	0	1
L:L:G152	R:R:N191	3.39	5	No	Yes	0	5	0	1
L:L:F154	R:R:Y103	12.38	4	Yes	Yes	0	4	0	1
L:L:F154	R:R:S295	5.28	4	Yes	No	0	4	0	1
L:L:A155	R:R:L298	3.15	0	No	No	0	4	0	1
L:L:F156	R:R:H95	9.05	0	No	No	0	6	0	1
L:L:F156	R:R:Y276	6.19	0	No	Yes	0	6	0	1
L:L:F156	R:R:T302	3.89	0	No	No	0	6	0	1
L:L:S157	R:R:N191	8.94	5	No	Yes	0	5	0	1
L:L:S157	R:R:R224	3.95	5	No	Yes	0	5	0	1
R:R:H95	R:R:Y98	6.53	0	No	No	6	5	1	2
R:R:Y103	R:R:Y98	11.91	0	Yes	No	4	5	1	2
R:R:A99	R:R:Y103	5.34	0	No	Yes	5	4	2	1
R:R:I120	R:R:R224	6.26	0	No	Yes	4	5	2	1
R:R:F124	R:R:R224	4.28	0	Yes	Yes	7	5	2	1
R:R:N191	R:R:R178	8.44	5	Yes	Yes	5	5	1	2
R:R:F190	R:R:S188	3.96	0	Yes	No	3	4	1	2
R:R:F190	R:R:N192	6.04	0	Yes	No	3	2	1	2
R:R:F193	R:R:N191	3.62	0	Yes	Yes	5	5	2	1
R:R:F193	R:R:H217	18.1	0	Yes	Yes	5	4	2	1
R:R:H217	R:R:T221	6.85	1	Yes	No	4	6	1	2
R:R:E283	R:R:H217	7.39	1	No	Yes	4	4	1	1
R:R:H217	R:R:L284	7.71	1	Yes	No	4	5	1	2
R:R:N280	R:R:Y276	10.47	0	No	Yes	5	6	2	1
R:R:L279	R:R:L298	4.15	0	No	No	4	4	2	1
R:R:F294	R:R:L282	3.65	0	Yes	No	5	5	1	2
R:R:E283	R:R:F294	3.5	1	No	Yes	4	5	1	1
R:R:P299	R:R:Y103	2.78	0	No	Yes	3	4	2	1
R:R:A181	R:R:F190	2.77	0	No	Yes	2	3	2	1
R:R:H286	R:R:T287	2.74	0	No	No	2	1	1	2
L:L:A155	R:R:Y276	2.67	0	No	Yes	0	6	0	1
R:R:F193	R:R:V220	2.62	0	Yes	No	5	5	2	2
R:R:R224	R:R:V220	2.62	0	Yes	No	5	5	1	2
R:R:F294	R:R:V293	2.62	0	Yes	No	5	1	1	2
R:R:F294	R:R:G291	1.51	0	Yes	No	5	2	1	2
R:R:A305	R:R:Y276	1.33	0	No	Yes	8	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8SG1_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.04
Number of Linked Nodes	268
Number of Links	283
Number of Hubs	32
Number of Links mediated by Hubs	128
Number of Communities	10
Number of Nodes involved in Communities	38
Number of Links involved in Communities	42

Path Summary
Number Of Nodes in MetaPath	58
Number Of Links MetaPath	57
Number of Shortest Paths	45500
Length Of Smallest Path	3
Average Path Length	17.1835
Length of Longest Path	38
Minimum Path Strength	1.39
Average Path Strength	5.55886
Maximum Path Strength	17.315
Minimum Path Correlation	0.7
Average Path Correlation	0.925796
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.44828
Average % Of Corr. Nodes	44.9818
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.3579
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• amide binding • binding • adipokinetic hormone binding • peptide hormone binding • hormone binding • molecular transducer activity • signaling receptor activity • protein-hormone receptor activity • adipokinetic hormone receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • G protein-coupled chemoattractant receptor activity • chemokine receptor activity • cytokine receptor activity • immune receptor activity • complement receptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • response to stimulus • immune response • immune system process • developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • system development • cellular response to stimulus • immune response-regulating cell surface receptor signaling pathway
Gene Ontology	Biological Process	• positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • response to stimulus • immune response • immune system process • developmental process • multicellular organism development • multicellular organismal process • skeletal system development • anatomical structure development • system development • cellular response to stimulus • immune response-regulating cell surface receptor signaling pathway • regulation of cellular process • complement receptor mediated signaling pathway • signaling • positive regulation of biological process • cell communication • positive regulation of response to stimulus • immune response-activating signaling pathway • immune response-regulating signaling pathway • positive regulation of immune response • regulation of immune system process • signal transduction • positive regulation of immune system process • regulation of biological process • cell surface receptor signaling pathway • immune response-activating cell surface receptor signaling pathway • regulation of response to stimulus • regulation of immune response • cellular process • activation of immune response • negative regulation of DNA-binding transcription factor activity • RNA metabolic process • regulation of primary metabolic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • negative regulation of NF-kappaB transcription factor activity • nucleic acid biosynthetic process • DNA-templated transcription • regulation of RNA metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • regulation of biosynthetic process • negative regulation of molecular function • primary metabolic process • regulation of macromolecule metabolic process • nucleobase-containing compound biosynthetic process • gene expression • macromolecule biosynthetic process • nucleic acid metabolic process • regulation of molecular function • regulation of gene expression • biosynthetic process • regulation of DNA-binding transcription factor activity • metabolic process • regulation of macromolecule biosynthetic process • regulation of DNA-templated transcription • macromolecule metabolic process • regulation of metabolic process • positive regulation of locomotion • regulation of cell motility • macrophage migration • positive regulation of chemotaxis • positive regulation of cell migration • taxis • cell migration • regulation of mononuclear cell migration • chemotaxis • regulation of leukocyte chemotaxis • regulation of leukocyte migration • positive regulation of macrophage migration • response to external stimulus • positive regulation of leukocyte chemotaxis • granulocyte migration • leukocyte migration • response to chemical • regulation of locomotion • regulation of response to external stimulus • macrophage chemotaxis • regulation of granulocyte chemotaxis • regulation of macrophage migration • positive regulation of response to external stimulus • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • cell motility • locomotion • positive regulation of cellular process • cell chemotaxis • regulation of macrophage chemotaxis • positive regulation of leukocyte migration • regulation of chemotaxis • cellular response to chemical stimulus • granulocyte chemotaxis • mononuclear cell migration • positive regulation of macrophage chemotaxis • leukocyte chemotaxis • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • regulation of signaling • regulation of signal transduction • intracellular signal transduction • regulation of intracellular signal transduction • calcium-mediated signaling • intracellular signaling cassette • regulation of calcium-mediated signaling • regulation of cell communication • defense response • response to stress • inflammatory response • negative regulation of biological process • regulation of interleukin-12 production • negative regulation of interleukin-12 production • cytokine production • negative regulation of cellular process • regulation of cytokine production • interleukin-12 production • negative regulation of macromolecule metabolic process • negative regulation of metabolic process • negative regulation of cytokine production • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of multicellular organismal process • fat cell differentiation • positive regulation of fat cell differentiation • regulation of developmental process • cellular developmental process • regulation of cell differentiation • positive regulation of developmental process • positive regulation of cell differentiation • cell differentiation • regulation of fat cell differentiation • cellular anatomical structure • membrane • cell periphery • plasma membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to peptide hormone • cell division • lymphocyte migration • T cell migration • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body • biological process involved in interspecies interaction between organisms • antifungal innate immune response • response to other organism • defense response to symbiont • response to biotic stimulus • defense response to fungus • defense response to other organism • innate immune response • response to external biotic stimulus • response to fungus • humoral immune response • antimicrobial humoral response • antifungal humoral response • insulin receptor signaling pathway • cell surface receptor protein tyrosine kinase signaling pathway • enzyme-linked receptor protein signaling pathway • cellular response to peptide hormone stimulus • response to insulin • cellular response to insulin stimulus • defense response to Gram-negative bacterium • defense response to bacterium • response to bacterium • digestive system development • tube development • embryo development • digestive tract development • embryonic organ development • embryonic digestive tract development • positive regulation of phosphorylation • regulation of protein modification process • regulation of protein phosphorylation • positive regulation of protein metabolic process • positive regulation of phosphate metabolic process • positive regulation of protein modification process • regulation of phosphate metabolic process • phosphate-containing compound metabolic process • positive regulation of macromolecule metabolic process • protein metabolic process • positive regulation of protein phosphorylation • phosphorus metabolic process • protein modification process • protein phosphorylation • positive regulation of phosphorus metabolic process • phosphorylation • regulation of protein metabolic process • macromolecule modification • regulation of phosphorus metabolic process • regulation of phosphorylation • lipid catabolic process • catabolic process • regulation of catabolic process • regulation of lipid catabolic process • diterpenoid metabolic process • retinoid metabolic process • terpenoid metabolic process • isoprenoid metabolic process • defense response to Gram-positive bacterium • vesicle lumen • intracellular vesicle • cytoplasmic vesicle lumen • secretory granule lumen • platelet dense granule lumen • cytoplasmic vesicle • platelet dense granule • secretory granule • secretory vesicle • extracellular matrix • external encapsulating structure • collagen-containing extracellular matrix
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q99788
Sequence	>8SG1_nogp_Chain_R A R V T R I F L V V V Y S I V C F L G I L G N G L V I I I A T F K M K K T V N M V W F L N L A V A D F L F N V F L P I H I T Y A A M D Y H W V F G T A M C K I S N F L L I H N M F T S V F L L T I I S S D R C I S V L L P V W S Q N H R S V R L A Y M A C M V I W V L A F F L S S P S L V F R D T A N L H G K I S C F N N F S L S D P V G Y S R H M V V T V T R F L C G F L V P V L I I T A C Y L T I V C K L Q R N R L A K T K K P F K I I V T I I I T F F L C W C P Y H T L N L L E L H H T A M P G S V F S L G L P L A T A L A I A N S C M N P I L Y V F M G Q D F K K F K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9L3Z	A	Protein	Chemerin	CML1	Homo sapiens	LRH7-C2	-	-	3.9	2025-03-12	doi.org/10.1093/procel/pwae073
	9L3W	A	Protein	Chemerin	CML1	Homo sapiens	Retinoic acid receptor responder protein 2	-	Gi1/β1/γ2	3.5	2025-03-12	doi.org/10.1093/procel/pwae073
	9L3W (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Retinoic acid receptor responder protein 2	-		3.5	2025-03-12	doi.org/10.1093/procel/pwae073
	8ZJG	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-	Gi1/β1/γ2	3.18	2025-01-22	doi.org/10.1038/s42003-024-07228-9
	8ZJG (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin	-		3.18	2025-01-22	doi.org/10.1038/s42003-024-07228-9
	8SG1	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/β1/γ2	2.94	2023-11-01	10.1371/journal.pbio.3002188
	8SG1 (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-		2.94	2023-11-01	10.1371/journal.pbio.3002188
	7YKD	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/β1/γ2	2.81	2023-04-19	10.1073/pnas.2214324120
	7YKD (No Gprot)	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-		2.81	2023-04-19	10.1073/pnas.2214324120

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