psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D9	A:A:S6	5.89	No	No	0	4	7
2	A:A:K17	A:A:V13	3.04	No	No	0	4	3
3	A:A:V13	B:B:N88	7.39	No	No	0	3	7
4	A:A:R15	B:B:H91	3.39	No	Yes	0	5	5
5	A:A:S16	B:B:N88	8.94	No	No	0	7	7
6	A:A:S16	B:B:K89	6.12	No	Yes	0	7	9
7	A:A:M18	A:A:N22	5.61	No	No	0	4	4
8	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
9	A:A:D20	A:A:R24	5.96	No	No	0	6	3
10	A:A:D20	B:B:K89	8.3	No	Yes	0	6	9
11	A:A:R21	A:A:R24	5.33	No	No	0	4	3
12	A:A:L23	B:B:K78	4.23	Yes	No	0	6	8
13	A:A:L23	B:B:I80	2.85	Yes	Yes	3	6	8
14	A:A:L23	B:B:K89	2.82	Yes	Yes	3	6	9
15	A:A:D26	A:A:E25	2.6	No	No	0	5	4
16	A:A:D26	B:B:K78	5.53	No	No	0	5	8
17	A:A:E28	A:A:R32	23.26	No	No	0	4	4
18	A:A:R32	R:R:S212	9.22	No	No	0	4	3
19	A:A:E33	A:A:H195	12.31	No	No	0	6	4
20	A:A:E33	A:A:K197	6.75	No	Yes	0	6	6
21	A:A:L36	A:A:V34	2.98	No	Yes	0	7	5
22	A:A:L194	A:A:V34	5.96	Yes	Yes	11	4	5
23	A:A:F196	A:A:V34	7.87	No	Yes	11	7	5
24	A:A:T219	A:A:V34	6.35	No	Yes	0	7	5
25	A:A:K197	A:A:K35	2.87	Yes	No	1	6	9
26	A:A:F199	A:A:K35	6.2	Yes	No	1	5	9
27	A:A:I222	A:A:L36	7.14	Yes	No	0	7	7
28	A:A:L37	A:A:L39	9.69	Yes	No	0	9	9
29	A:A:F215	A:A:L37	7.31	Yes	Yes	1	9	9
30	A:A:L37	A:A:V218	2.98	Yes	No	1	9	9
31	A:A:I221	A:A:L37	4.28	Yes	Yes	1	8	9
32	A:A:K46	A:A:L38	7.05	Yes	No	0	9	8
33	A:A:L38	A:A:M198	7.07	No	Yes	0	8	7
34	A:A:I222	A:A:L38	2.85	Yes	No	0	7	8
35	A:A:I253	A:A:L39	5.71	Yes	No	0	8	9
36	A:A:A41	A:A:S246	3.42	No	Yes	0	7	9
37	A:A:E43	A:A:K46	6.75	No	Yes	0	9	9
38	A:A:E43	A:A:S47	2.87	No	No	0	9	9
39	A:A:D229	A:A:S44	4.42	Yes	No	0	8	9
40	A:A:D200	A:A:K46	12.44	No	Yes	0	9	9
41	A:A:C224	A:A:K46	3.23	Yes	Yes	0	7	9
42	A:A:I49	A:A:Q52	2.74	Yes	No	0	7	9
43	A:A:C224	A:A:I49	3.27	Yes	Yes	12	7	7
44	A:A:F267	A:A:I49	2.51	Yes	Yes	12	9	7
45	A:A:I49	A:A:N269	2.83	Yes	Yes	12	7	9
46	A:A:T187	A:A:V50	3.17	No	No	16	6	6
47	A:A:M198	A:A:V50	3.04	Yes	No	16	7	6
48	A:A:Q52	A:A:T327	5.67	No	No	0	9	8
49	A:A:N331	A:A:Q52	11.88	Yes	No	0	8	9
50	A:A:F189	A:A:M53	13.68	No	No	0	9	8
51	A:A:M198	A:A:M53	4.33	Yes	No	0	7	8
52	A:A:G183	A:A:Q204	3.29	No	Yes	0	9	9
53	A:A:F199	A:A:I184	3.77	Yes	Yes	1	5	9
54	A:A:I184	A:A:V201	4.61	Yes	Yes	1	9	9
55	A:A:F215	A:A:I184	3.77	Yes	Yes	1	9	9
56	A:A:I184	B:B:W99	4.7	Yes	Yes	1	9	9
57	A:A:E186	A:A:H188	13.54	No	No	1	9	3
58	A:A:E186	A:A:K197	9.45	No	Yes	1	9	6
59	A:A:E186	A:A:F199	11.66	No	Yes	1	9	5
60	A:A:M198	A:A:T187	4.52	Yes	No	16	7	6
61	A:A:H188	A:A:K197	13.1	No	Yes	1	3	6
62	A:A:F189	A:A:F196	21.43	No	No	0	9	7
63	A:A:H195	A:A:T190	8.21	No	No	0	4	3
64	A:A:F191	A:A:K192	16.13	Yes	No	11	5	4
65	A:A:F191	A:A:V332	9.18	Yes	No	0	5	7
66	A:A:F191	A:A:F336	6.43	Yes	Yes	11	5	8
67	A:A:F336	A:A:K192	6.2	Yes	No	11	8	4
68	A:A:F196	A:A:L194	10.96	No	Yes	11	7	4
69	A:A:F336	A:A:L194	3.65	Yes	Yes	11	8	4
70	A:A:L194	R:R:M208	5.65	Yes	Yes	11	4	4
71	A:A:F199	A:A:K197	8.69	Yes	Yes	1	5	6
72	A:A:F199	A:A:F215	4.29	Yes	Yes	1	5	9
73	A:A:F199	B:B:W99	15.03	Yes	Yes	1	5	9
74	A:A:Q204	A:A:V201	4.3	Yes	Yes	1	9	9
75	A:A:V201	A:A:W211	11.03	Yes	Yes	1	9	9
76	A:A:F215	A:A:V201	3.93	Yes	Yes	1	9	9
77	A:A:Q204	A:A:S206	2.89	Yes	No	1	9	8
78	A:A:Q204	A:A:W211	12.05	Yes	Yes	1	9	9
79	A:A:S206	B:B:Y145	2.54	No	Yes	1	8	8
80	A:A:S206	B:B:D186	2.94	No	Yes	1	8	9
81	A:A:E207	A:A:K209	4.05	Yes	No	0	9	8
82	A:A:E207	A:A:K210	4.05	Yes	Yes	1	9	9
83	A:A:E207	B:B:D186	3.9	Yes	Yes	1	9	9
84	A:A:E207	B:B:C204	3.04	Yes	Yes	1	9	7
85	A:A:R208	A:A:W211	8	Yes	Yes	1	9	9
86	A:A:I212	A:A:R208	8.77	No	Yes	1	8	9
87	A:A:L249	A:A:R208	3.64	No	Yes	0	9	9
88	A:A:R208	A:A:S252	3.95	Yes	No	0	9	7
89	A:A:I253	A:A:R208	3.76	Yes	Yes	0	8	9
90	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
91	A:A:K210	B:B:M188	7.2	Yes	Yes	1	9	8
92	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
93	A:A:K210	B:B:D228	5.53	Yes	No	1	9	9
94	A:A:K210	B:B:N230	4.2	Yes	No	1	9	9
95	A:A:K210	B:B:D246	2.77	Yes	No	1	9	9
96	A:A:I212	A:A:W211	4.7	No	Yes	1	8	9
97	A:A:F215	A:A:W211	5.01	Yes	Yes	1	9	9
98	A:A:W211	B:B:L117	3.42	Yes	Yes	1	9	9
99	A:A:F259	A:A:I212	5.02	Yes	No	1	9	8
100	A:A:C214	A:A:H213	2.95	Yes	Yes	1	7	8
101	A:A:H213	A:A:W258	6.35	Yes	Yes	1	8	5
102	A:A:H213	B:B:Y59	6.53	Yes	Yes	1	8	8
103	A:A:H213	B:B:R314	3.39	Yes	Yes	1	8	8
104	A:A:H213	B:B:W332	7.41	Yes	Yes	1	8	9
105	A:A:C214	B:B:Y59	5.38	Yes	Yes	1	7	8
106	A:A:C214	B:B:Q75	9.16	Yes	No	1	7	9
107	A:A:C214	B:B:W99	2.61	Yes	Yes	1	7	9
108	A:A:C214	B:B:L117	3.17	Yes	Yes	1	7	9
109	A:A:F215	A:A:V218	3.93	Yes	No	1	9	9
110	A:A:F215	B:B:W99	7.02	Yes	Yes	1	9	9
111	A:A:E216	A:A:W258	9.81	No	Yes	0	7	5
112	A:A:E216	B:B:K57	5.4	No	No	0	7	9
113	A:A:I221	A:A:I253	2.94	Yes	Yes	0	8	8
114	A:A:F259	A:A:I221	7.54	Yes	Yes	1	9	8
115	A:A:I221	A:A:T262	3.04	Yes	No	1	8	7
116	A:A:I222	A:A:I265	2.94	Yes	Yes	12	7	8
117	A:A:F267	A:A:I222	3.77	Yes	Yes	12	9	7
118	A:A:F223	A:A:V225	2.62	Yes	Yes	7	9	7
119	A:A:F223	A:A:S246	2.64	Yes	Yes	7	9	9
120	A:A:F223	A:A:L249	6.09	Yes	No	0	9	9
121	A:A:F223	A:A:F250	16.08	Yes	Yes	7	9	9
122	A:A:F223	A:A:I253	5.02	Yes	Yes	0	9	8
123	A:A:C224	A:A:N269	3.15	Yes	Yes	12	7	9
124	A:A:M243	A:A:V225	3.04	No	Yes	7	8	7
125	A:A:S246	A:A:V225	6.46	Yes	Yes	7	9	7
126	A:A:L268	A:A:V225	4.47	No	Yes	0	8	7
127	A:A:F307	A:A:V225	7.87	Yes	Yes	7	8	7
128	A:A:A226	A:A:D229	6.18	No	Yes	0	8	8
129	A:A:L227	A:A:L268	9.69	No	No	0	7	8
130	A:A:F274	A:A:L227	7.31	Yes	No	0	9	7
131	A:A:I303	A:A:L227	2.85	Yes	No	0	7	7
132	A:A:D229	A:A:S228	5.89	Yes	No	0	8	9
133	A:A:K270	A:A:S228	7.65	No	No	0	9	9
134	A:A:D229	A:A:L232	4.07	Yes	Yes	10	8	8
135	A:A:D229	A:A:R242	11.91	Yes	No	10	8	9
136	A:A:D231	A:A:Y230	25.29	Yes	Yes	10	9	8
137	A:A:F274	A:A:Y230	5.16	Yes	Yes	10	9	8
138	A:A:K277	A:A:Y230	9.55	Yes	Yes	10	9	8
139	A:A:S281	A:A:Y230	8.9	No	Yes	10	7	8
140	A:A:C286	A:A:Y230	4.03	Yes	Yes	0	6	8
141	A:A:D231	A:A:L232	2.71	Yes	Yes	10	9	8
142	A:A:D231	A:A:K277	12.44	Yes	Yes	10	9	9
143	A:A:D231	A:A:S281	5.89	Yes	No	10	9	7
144	A:A:L232	A:A:R242	8.5	Yes	No	10	8	9
145	A:A:K277	A:A:L232	4.23	Yes	Yes	10	9	8
146	A:A:N241	A:A:V233	7.39	No	No	0	9	5
147	A:A:E245	A:A:N241	3.94	No	No	0	9	9
148	A:A:C286	A:A:M243	3.24	Yes	No	0	6	8
149	A:A:F307	A:A:M243	2.49	Yes	No	7	8	8
150	A:A:C286	A:A:H244	5.9	Yes	No	0	6	4
151	A:A:F307	A:A:S246	3.96	Yes	Yes	7	8	9
152	A:A:M247	A:A:Y287	8.38	No	Yes	0	6	7
153	A:A:F307	A:A:M247	6.22	Yes	No	0	8	6
154	A:A:L310	A:A:M247	7.07	No	No	0	4	6
155	A:A:C254	A:A:F250	5.59	Yes	Yes	7	5	9
156	A:A:F250	A:A:I264	3.77	Yes	No	7	9	6
157	A:A:F250	A:A:L266	7.31	Yes	No	7	9	9
158	A:A:F250	A:A:F307	6.43	Yes	Yes	7	9	8
159	A:A:F250	A:A:L310	6.09	Yes	No	0	9	4
160	A:A:F250	A:A:I319	2.51	Yes	No	7	9	5
161	A:A:D251	A:A:N255	8.08	No	No	0	5	8
162	A:A:C254	A:A:I264	3.27	Yes	No	7	5	6
163	A:A:C254	A:A:K317	6.47	Yes	No	7	5	7
164	A:A:K312	A:A:N255	9.79	No	No	0	5	8
165	A:A:K257	A:A:N256	2.8	No	No	1	4	8
166	A:A:N256	A:A:W258	9.04	No	Yes	1	8	5
167	A:A:F259	A:A:N256	3.62	Yes	No	1	9	8
168	A:A:K257	A:A:W258	13.92	No	Yes	1	4	5
169	A:A:W258	B:B:R314	3	Yes	Yes	1	5	8
170	A:A:W258	B:B:W332	2.81	Yes	Yes	1	5	9
171	A:A:F259	A:A:T262	9.08	Yes	No	1	9	7
172	A:A:R313	A:A:T260	5.17	No	No	0	4	3
173	A:A:E318	A:A:S263	8.62	No	No	17	4	7
174	A:A:S263	A:A:Y320	3.82	No	Yes	17	7	7
175	A:A:S263	A:A:V342	3.23	No	No	0	7	7
176	A:A:I264	A:A:K317	5.82	No	No	7	6	7
177	A:A:F267	A:A:I265	3.77	Yes	Yes	12	9	8
178	A:A:F334	A:A:I265	2.51	No	Yes	0	3	8
179	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
180	A:A:I319	A:A:L266	2.85	No	No	7	5	9
181	A:A:L266	A:A:T321	4.42	No	No	0	9	5
182	A:A:F267	A:A:N269	3.62	Yes	Yes	12	9	9
183	A:A:F267	A:A:H322	3.39	Yes	No	12	9	9
184	A:A:F267	A:A:T324	6.49	Yes	No	12	9	9
185	A:A:F267	A:A:N331	4.83	Yes	Yes	12	9	8
186	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
187	A:A:F323	A:A:L268	6.09	Yes	No	0	4	8
188	A:A:N269	A:A:T324	8.77	Yes	No	12	9	9
189	A:A:K270	A:A:L273	8.46	No	No	0	9	6
190	A:A:K271	A:A:Y296	7.17	No	Yes	0	5	4
191	A:A:F323	A:A:K271	2.48	Yes	No	0	4	5
192	A:A:D272	A:A:L273	4.07	No	No	0	9	6
193	A:A:F274	A:A:I278	6.28	Yes	Yes	10	9	6
194	A:A:F274	A:A:Y296	3.09	Yes	Yes	0	9	4
195	A:A:A299	A:A:F274	2.77	No	Yes	10	7	9
196	A:A:E275	A:A:Y296	28.06	No	Yes	0	5	4
197	A:A:E276	A:A:K277	5.4	No	Yes	0	5	9
198	A:A:I278	A:A:K279	2.91	Yes	No	0	6	2
199	A:A:I278	A:A:N294	4.25	Yes	No	0	6	3
200	A:A:A299	A:A:I278	3.25	No	Yes	10	7	6
201	A:A:N294	A:A:P282	6.52	No	No	0	3	5
202	A:A:L283	A:A:Y287	4.69	No	Yes	7	7	7
203	A:A:L283	A:A:Y290	7.03	No	Yes	0	7	7
204	A:A:I303	A:A:L283	4.28	Yes	No	7	7	7
205	A:A:T284	A:A:Y290	3.75	No	Yes	0	4	7
206	A:A:C286	A:A:Y287	6.72	Yes	Yes	0	6	7
207	A:A:E289	A:A:Y287	3.37	No	Yes	0	6	7
208	A:A:Y287	A:A:Y302	5.96	Yes	No	7	7	6
209	A:A:I303	A:A:Y287	4.84	Yes	Yes	7	7	7
210	A:A:Q306	A:A:Y287	9.02	No	Yes	7	5	7
211	A:A:E289	A:A:P288	11	No	No	0	6	5
212	A:A:G292	A:A:Y290	2.9	No	Yes	0	7	7
213	A:A:Y290	A:A:Y302	16.88	Yes	No	0	7	6
214	A:A:S293	A:A:T295	6.4	No	No	15	3	5
215	A:A:E298	A:A:S293	2.87	No	No	15	4	3
216	A:A:E297	A:A:T295	9.88	No	No	15	4	5
217	A:A:E298	A:A:T295	5.64	No	No	15	4	5
218	A:A:E297	A:A:Y296	6.73	No	Yes	0	4	4
219	A:A:E297	A:A:E298	3.81	No	No	15	4	4
220	A:A:A300	A:A:F323	2.77	No	Yes	0	5	4
221	A:A:Q306	A:A:Y302	18.04	No	No	7	5	6
222	A:A:F307	A:A:I303	2.51	Yes	Yes	7	8	7
223	A:A:Q304	A:A:T321	12.76	No	No	0	5	5
224	A:A:F323	A:A:Q304	7.03	Yes	No	0	4	5
225	A:A:D309	A:A:K314	4.15	No	No	0	4	3
226	A:A:K314	A:A:N311	9.79	No	No	0	3	8
227	A:A:I319	A:A:N311	5.66	No	No	0	5	8
228	A:A:K312	A:A:R313	2.48	No	No	0	5	4
229	A:A:R313	A:A:T316	2.59	No	No	0	4	3
230	A:A:D315	A:A:T316	8.67	No	No	0	3	3
231	A:A:E318	A:A:Y320	13.47	No	Yes	17	4	7
232	A:A:E318	A:A:K345	2.7	No	No	0	4	5
233	A:A:A338	A:A:Y320	8.01	No	Yes	0	6	7
234	A:A:D341	A:A:Y320	6.9	No	Yes	0	8	7
235	A:A:Y320	R:R:R305	10.29	Yes	No	0	7	3
236	A:A:H322	A:A:N331	6.38	No	Yes	12	9	8
237	A:A:F334	A:A:H322	21.5	No	No	0	3	9
238	A:A:N331	A:A:T324	5.85	Yes	No	12	8	9
239	A:A:C325	A:A:D328	7.78	No	No	0	7	9
240	A:A:C325	A:A:N331	11.02	No	Yes	0	7	8
241	A:A:D337	A:A:Q333	9.14	No	No	0	4	5
242	A:A:F336	A:A:T340	7.78	Yes	No	11	8	6
243	A:A:F336	R:R:M208	4.98	Yes	Yes	11	8	4
244	A:A:D341	A:A:T340	2.89	No	No	0	8	6
245	A:A:T340	R:R:M208	3.01	No	Yes	11	6	4
246	A:A:D341	R:R:N304	8.08	No	No	0	8	4
247	A:A:N346	A:A:V342	2.96	No	No	0	4	7
248	A:A:I343	A:A:N347	4.25	No	Yes	0	7	8
249	A:A:I343	R:R:M208	2.92	No	Yes	0	7	4
250	A:A:I344	A:A:L348	2.85	No	Yes	0	6	9
251	A:A:I344	R:R:P207	5.08	No	No	0	6	8
252	A:A:D350	A:A:N347	4.04	Yes	Yes	0	4	8
253	A:A:N347	R:R:A203	4.69	Yes	No	0	8	8
254	A:A:N347	R:R:S210	2.98	Yes	No	0	8	5
255	A:A:L348	A:A:L353	5.54	Yes	No	0	9	7
256	A:A:L348	R:R:V204	2.98	Yes	No	0	9	8
257	A:A:L348	R:R:L297	2.77	Yes	Yes	18	9	8
258	A:A:L348	R:R:A311	3.15	Yes	No	18	9	7
259	A:A:F354	A:A:K349	4.96	No	No	0	5	5
260	A:A:C351	A:A:D350	4.67	Yes	Yes	2	4	4
261	A:A:D350	R:R:K135	9.68	Yes	No	0	4	7
262	A:A:D350	R:R:R214	5.96	Yes	Yes	2	4	7
263	A:A:C351	R:R:R200	4.18	Yes	Yes	2	4	9
264	A:A:C351	R:R:R214	4.18	Yes	Yes	2	4	7
265	A:A:G352	R:R:S375	3.71	No	No	0	8	7
266	A:A:L353	R:R:R200	14.58	No	Yes	0	7	9
267	B:B:D5	B:B:Q6	10.44	No	No	0	1	1
268	B:B:L7	G:G:V16	2.98	Yes	No	0	8	7
269	B:B:E12	B:B:Q9	7.65	No	No	0	4	3
270	B:B:Q13	B:B:Q9	7.68	No	No	0	1	3
271	B:B:A11	G:G:L15	3.15	No	No	0	5	2
272	B:B:E12	B:B:N16	7.89	No	No	0	4	1
273	B:B:N16	B:B:Q13	6.6	No	No	0	1	1
274	B:B:L14	G:G:L19	4.15	No	No	0	8	9
275	B:B:N16	B:B:R19	10.85	No	No	0	1	4
276	B:B:I18	B:B:Q17	4.12	Yes	No	0	7	4
277	B:B:Q17	G:G:A23	3.03	No	No	0	4	8
278	B:B:I18	G:G:E22	4.1	Yes	Yes	5	7	9
279	B:B:I18	G:G:R27	6.26	Yes	Yes	5	7	8
280	B:B:D20	B:B:R19	11.91	No	No	0	2	4
281	B:B:D258	B:B:R22	14.29	Yes	No	0	7	6
282	B:B:Q259	B:B:R22	4.67	No	No	0	6	6
283	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
284	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
285	B:B:D27	G:G:K29	15.21	No	No	0	8	4
286	B:B:D27	G:G:S31	5.89	No	No	0	8	9
287	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
288	B:B:L30	B:B:T34	5.9	No	No	0	5	5
289	B:B:L30	B:B:M262	7.07	No	Yes	0	5	4
290	B:B:L30	G:G:A34	4.73	No	No	0	5	6
291	B:B:I33	B:B:N36	2.83	No	No	0	3	1
292	B:B:L300	B:B:T34	2.95	Yes	No	0	6	5
293	B:B:K301	B:B:T34	3	Yes	No	0	5	5
294	B:B:I37	B:B:R283	3.76	No	Yes	13	2	9
295	B:B:I37	B:B:L300	2.85	No	Yes	13	2	6
296	B:B:I37	G:G:M38	2.92	No	No	13	2	4
297	B:B:G41	B:B:P39	4.06	No	No	0	1	1
298	B:B:K301	B:B:P39	10.04	Yes	No	0	5	1
299	B:B:I43	B:B:V40	4.61	No	No	0	3	3
300	B:B:V40	G:G:L51	4.47	No	Yes	0	3	6
301	B:B:I43	B:B:L284	4.28	No	No	0	3	5
302	B:B:M45	G:G:L50	2.83	No	No	0	4	9
303	B:B:R46	B:B:R48	12.79	No	No	0	5	7
304	B:B:K337	B:B:T47	12.01	Yes	No	14	6	3
305	B:B:T47	B:B:W339	8.49	No	Yes	14	3	9
306	B:B:R49	B:B:T87	3.88	No	No	0	7	5
307	B:B:I338	B:B:R49	5.01	No	No	3	5	7
308	B:B:R49	G:G:F61	7.48	No	Yes	3	7	8
309	B:B:R52	B:B:T50	7.76	No	No	0	7	3
310	B:B:L51	B:B:L70	2.77	Yes	Yes	3	9	5
311	B:B:L51	B:B:W82	18.22	Yes	Yes	3	9	9
312	B:B:L51	B:B:T87	4.42	Yes	No	0	9	5
313	B:B:L336	B:B:L51	5.54	No	Yes	0	7	9
314	B:B:I338	B:B:L51	5.71	No	Yes	3	5	9
315	B:B:F335	B:B:R52	4.28	Yes	No	0	4	7
316	B:B:H54	B:B:I58	10.61	Yes	No	0	9	9
317	B:B:H54	B:B:S72	5.58	Yes	No	3	9	9
318	B:B:H54	B:B:S74	9.76	Yes	No	3	9	9
319	B:B:D76	B:B:H54	5.04	Yes	Yes	3	9	9
320	B:B:H54	B:B:I80	13.26	Yes	Yes	3	9	8
321	B:B:H54	B:B:W82	3.17	Yes	Yes	3	9	9
322	B:B:A56	B:B:D76	3.09	No	Yes	0	7	9
323	B:B:K57	B:B:Y59	11.94	No	Yes	1	9	8
324	B:B:K57	B:B:W332	23.21	No	Yes	1	9	9
325	B:B:Q75	B:B:Y59	19.16	No	Yes	1	9	8
326	B:B:W332	B:B:Y59	4.82	Yes	Yes	1	9	8
327	B:B:M61	B:B:W63	5.82	Yes	Yes	3	6	7
328	B:B:L70	B:B:M61	5.65	Yes	Yes	3	5	6
329	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
330	B:B:A328	B:B:M61	3.22	No	Yes	3	5	6
331	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
332	B:B:H62	B:B:R150	12.41	No	No	0	6	6
333	B:B:L70	B:B:W63	11.39	Yes	Yes	3	5	7
334	B:B:S84	B:B:W63	4.94	No	Yes	3	5	7
335	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
336	B:B:T321	B:B:W63	13.34	No	Yes	0	7	7
337	B:B:A328	B:B:W63	3.89	No	Yes	3	5	7
338	B:B:G64	B:B:Y105	5.79	No	Yes	0	5	6
339	B:B:D66	B:B:R68	3.57	No	No	0	8	5
340	B:B:D66	B:B:L69	4.07	No	No	0	8	5
341	B:B:S67	B:B:T321	4.8	No	No	0	5	7
342	B:B:D322	B:B:S67	2.94	No	No	0	1	5
343	B:B:D323	B:B:S67	11.78	No	No	0	7	5
344	B:B:D83	B:B:R68	15.48	No	No	3	8	5
345	B:B:R68	B:B:Y85	31.9	No	Yes	3	5	4
346	B:B:I81	B:B:L69	4.28	Yes	No	6	7	5
347	B:B:L69	B:B:Y105	7.03	No	Yes	6	5	6
348	B:B:L70	B:B:W82	6.83	Yes	Yes	3	5	9
349	B:B:L79	B:B:V71	4.47	Yes	Yes	6	7	8
350	B:B:I81	B:B:V71	3.07	Yes	Yes	6	7	8
351	B:B:C103	B:B:V71	3.42	Yes	Yes	6	8	8
352	B:B:V71	B:B:Y105	5.05	Yes	Yes	6	8	6
353	B:B:V112	B:B:V71	4.81	No	Yes	6	8	8
354	B:B:S72	B:B:W82	4.94	No	Yes	3	9	9
355	B:B:L336	B:B:S72	3	No	No	0	7	9
356	B:B:A73	B:B:V100	5.09	No	No	0	9	9
357	B:B:A73	B:B:C103	3.61	No	Yes	0	9	8
358	B:B:D76	B:B:S74	10.31	Yes	No	3	9	9
359	B:B:Q75	B:B:W99	7.67	No	Yes	1	9	9
360	B:B:D76	B:B:K78	8.3	Yes	No	0	9	8
361	B:B:G77	B:B:S98	3.71	No	No	0	8	8
362	B:B:I93	B:B:L79	5.71	Yes	Yes	6	7	7
363	B:B:L79	B:B:L95	5.54	Yes	Yes	6	7	8
364	B:B:C103	B:B:L79	3.17	Yes	Yes	6	8	7
365	B:B:C114	B:B:L79	6.35	Yes	Yes	6	8	7
366	B:B:I80	B:B:W82	16.44	Yes	Yes	3	8	9
367	B:B:I80	B:B:K89	5.82	Yes	Yes	3	8	9
368	B:B:I81	B:B:V90	4.61	Yes	No	6	7	5
369	B:B:H91	B:B:I81	3.98	Yes	Yes	6	5	7
370	B:B:I81	B:B:Y105	3.63	Yes	Yes	6	7	6
371	B:B:I81	B:B:L126	4.28	Yes	Yes	6	7	5
372	B:B:K89	B:B:W82	10.44	Yes	Yes	3	9	9
373	B:B:D83	B:B:Y85	4.6	No	Yes	3	8	4
374	B:B:D83	B:B:T86	11.56	No	No	0	8	6
375	B:B:S84	B:B:Y85	2.54	No	Yes	3	5	4
376	B:B:S84	G:G:F61	5.28	No	Yes	3	5	8
377	B:B:Y85	G:G:P60	11.13	Yes	Yes	3	4	9
378	B:B:Y85	G:G:F61	7.22	Yes	Yes	3	4	8
379	B:B:N88	B:B:T86	11.7	No	No	0	7	6
380	B:B:H91	B:B:V90	5.54	Yes	No	6	5	5
381	B:B:H91	B:B:V133	4.15	Yes	Yes	6	5	4
382	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
383	B:B:I93	B:B:Y124	4.84	Yes	Yes	6	7	6
384	B:B:I93	B:B:V133	6.14	Yes	Yes	6	7	4
385	B:B:L95	B:B:V100	4.47	Yes	No	6	8	9
386	B:B:C114	B:B:L95	4.76	Yes	Yes	6	8	8
387	B:B:L95	B:B:Y124	5.86	Yes	Yes	6	8	6
388	B:B:R96	B:B:V135	5.23	No	No	0	6	4
389	B:B:E138	B:B:R96	9.3	No	No	0	6	6
390	B:B:S97	B:B:W99	3.71	No	Yes	0	8	9
391	B:B:D118	B:B:S97	7.36	No	No	0	9	8
392	B:B:L117	B:B:W99	3.42	Yes	Yes	1	9	9
393	B:B:C114	B:B:V100	3.42	Yes	No	6	8	9
394	B:B:G116	B:B:M101	3.49	No	No	0	9	9
395	B:B:L117	B:B:M101	4.24	Yes	No	0	9	9
396	B:B:C148	B:B:T102	3.38	No	No	0	6	8
397	B:B:C149	B:B:T102	3.38	No	No	0	8	8
398	B:B:A104	B:B:R150	2.77	No	No	0	7	6
399	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
400	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
401	B:B:V112	B:B:Y105	5.05	No	Yes	6	8	6
402	B:B:L126	B:B:Y105	3.52	Yes	Yes	6	5	6
403	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
404	B:B:G109	B:B:S108	3.71	No	No	0	5	6
405	B:B:N110	B:B:S108	11.92	Yes	No	1	4	6
406	B:B:D154	B:B:S108	8.83	Yes	No	1	6	6
407	B:B:N110	B:B:Y111	4.65	Yes	Yes	1	4	4
408	B:B:K127	B:B:N110	4.2	No	Yes	0	4	4
409	B:B:D154	B:B:N110	4.04	Yes	Yes	1	6	4
410	B:B:I123	B:B:Y111	3.63	Yes	Yes	1	6	4
411	B:B:N125	B:B:Y111	10.47	No	Yes	0	4	4
412	B:B:S136	B:B:Y111	3.82	No	Yes	1	4	4
413	B:B:D154	B:B:Y111	6.9	Yes	Yes	1	6	4
414	B:B:L126	B:B:V112	2.98	Yes	No	6	5	8
415	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
416	B:B:C114	B:B:Y124	2.69	Yes	Yes	6	8	6
417	B:B:G115	B:B:L146	3.42	No	No	0	9	7
418	B:B:D118	B:B:I120	9.8	No	No	0	9	6
419	B:B:E138	B:B:I120	6.83	No	No	0	6	6
420	B:B:C121	B:B:L146	3.17	No	No	1	8	7
421	B:B:C121	B:B:T159	3.38	No	Yes	1	8	9
422	B:B:C121	B:B:W169	2.61	No	Yes	1	8	8
423	B:B:S122	B:B:Y124	10.17	No	Yes	6	8	6
424	B:B:S122	B:B:V135	3.23	No	No	6	8	4
425	B:B:I123	B:B:S136	3.1	Yes	No	1	6	4
426	B:B:I123	B:B:L139	2.85	Yes	Yes	0	6	9
427	B:B:F151	B:B:I123	5.02	Yes	Yes	1	9	6
428	B:B:I123	B:B:I157	2.94	Yes	Yes	1	6	7
429	B:B:I123	B:B:I171	5.89	Yes	Yes	1	6	6
430	B:B:V133	B:B:Y124	2.52	Yes	Yes	6	4	6
431	B:B:V135	B:B:Y124	7.57	No	Yes	6	4	6
432	B:B:L126	B:B:V133	4.47	Yes	Yes	6	5	4
433	B:B:R134	B:B:T128	2.59	No	No	0	3	3
434	B:B:E130	B:B:N132	7.89	No	No	0	3	3
435	B:B:N132	B:B:R134	3.62	No	No	0	3	3
436	B:B:R137	B:B:S136	2.64	No	No	0	5	4
437	B:B:L139	B:B:R137	3.64	Yes	No	0	9	5
438	B:B:I171	B:B:R137	2.51	Yes	No	0	6	5
439	B:B:L139	B:B:W169	11.39	Yes	Yes	0	9	8
440	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
441	B:B:H142	B:B:S161	12.55	Yes	No	1	9	9
442	B:B:D163	B:B:H142	6.3	Yes	Yes	1	9	9
443	B:B:H142	B:B:T165	2.74	Yes	Yes	1	9	7
444	B:B:A167	B:B:H142	2.93	No	Yes	1	4	9
445	B:B:H142	B:B:W169	12.7	Yes	Yes	1	9	8
446	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
447	B:B:D163	B:B:G144	5.03	Yes	No	0	9	8
448	B:B:S147	B:B:Y145	2.54	No	Yes	0	9	8
449	B:B:G162	B:B:Y145	10.14	No	Yes	1	9	8
450	B:B:D186	B:B:Y145	8.05	Yes	Yes	1	9	8
451	B:B:M188	B:B:Y145	4.79	Yes	Yes	1	8	8
452	B:B:L146	B:B:T159	2.95	No	Yes	1	7	9
453	B:B:S147	B:B:S160	4.89	No	Yes	0	9	6
454	B:B:C148	B:B:R150	4.18	No	No	0	6	6
455	B:B:C148	B:B:L190	7.94	No	Yes	0	6	5
456	B:B:C149	B:B:I157	4.91	No	Yes	1	8	7
457	B:B:C149	B:B:T159	3.38	No	Yes	1	8	9
458	B:B:F151	B:B:I157	6.28	Yes	Yes	1	9	7
459	B:B:F151	B:B:I171	2.51	Yes	Yes	1	9	6
460	B:B:L152	B:B:Q156	5.32	Yes	No	0	3	5
461	B:B:L152	B:B:V158	2.98	Yes	No	9	3	5
462	B:B:L152	B:B:L192	5.54	Yes	No	9	3	5
463	B:B:L152	B:B:T196	4.42	Yes	No	9	3	1
464	B:B:D153	B:B:N155	8.08	No	No	0	5	3
465	B:B:L168	B:B:Q156	3.99	No	No	0	6	5
466	B:B:I157	B:B:T159	3.04	Yes	Yes	1	7	9
467	B:B:I157	B:B:I171	5.89	Yes	Yes	1	7	6
468	B:B:L190	B:B:V158	4.47	Yes	No	9	5	5
469	B:B:F199	B:B:V158	7.87	Yes	No	9	9	5
470	B:B:T159	B:B:W169	15.77	Yes	Yes	1	9	8
471	B:B:C166	B:B:S160	3.44	Yes	Yes	0	8	6
472	B:B:S160	B:B:V187	8.08	Yes	Yes	0	6	9
473	B:B:L190	B:B:S160	4.5	Yes	Yes	0	5	6
474	B:B:G162	B:B:S161	3.71	No	No	1	9	9
475	B:B:D163	B:B:S161	10.31	Yes	No	1	9	9
476	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
477	B:B:D163	B:B:T165	7.23	Yes	Yes	1	9	7
478	B:B:G185	B:B:T164	3.64	No	No	0	5	6
479	B:B:T165	B:B:T179	4.71	Yes	No	1	7	4
480	B:B:C166	B:B:F180	4.19	Yes	Yes	9	8	7
481	B:B:C166	B:B:F199	4.19	Yes	Yes	9	8	9
482	B:B:C166	B:B:S201	3.44	Yes	Yes	9	8	9
483	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
484	B:B:A167	B:B:Q176	3.03	No	No	1	4	4
485	B:B:F180	B:B:L168	3.65	Yes	No	0	7	6
486	B:B:Q176	B:B:W169	7.67	No	Yes	1	4	8
487	B:B:D170	B:B:T173	11.56	No	No	0	9	5
488	B:B:Q175	B:B:T173	7.09	No	No	0	4	5
489	B:B:Q176	B:B:T179	9.92	No	No	1	4	4
490	B:B:F180	B:B:T178	10.38	Yes	No	0	7	4
491	B:B:F180	B:B:F199	10.72	Yes	Yes	9	7	9
492	B:B:F180	B:B:W211	16.04	Yes	Yes	9	7	8
493	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
494	B:B:H183	B:B:V187	6.92	Yes	Yes	9	9	9
495	B:B:H183	B:B:S201	5.58	Yes	Yes	9	9	9
496	B:B:A203	B:B:H183	8.78	No	Yes	9	8	9
497	B:B:H183	B:B:S207	2.79	Yes	Yes	0	9	5
498	B:B:H183	B:B:K209	17.03	Yes	Yes	9	9	6
499	B:B:D205	B:B:T184	15.9	No	No	0	9	3
500	B:B:S201	B:B:V187	3.23	Yes	Yes	9	9	9
501	B:B:A203	B:B:V187	5.09	No	Yes	9	8	9
502	B:B:C204	B:B:M188	3.24	Yes	Yes	1	7	8
503	B:B:M188	B:B:N230	4.21	Yes	No	1	8	9
504	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
505	B:B:F199	B:B:L190	3.65	Yes	Yes	9	9	5
506	B:B:C233	B:B:S191	3.44	No	No	0	3	8
507	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
508	B:B:L192	B:B:T196	2.95	No	No	9	5	1
509	B:B:A193	B:B:D195	3.09	No	No	0	4	5
510	B:B:A193	B:B:F234	5.55	No	Yes	0	4	5
511	B:B:G238	B:B:P194	4.06	No	No	0	7	4
512	B:B:D195	B:B:R197	15.48	No	No	0	5	5
513	B:B:R197	B:B:R214	9.6	No	No	0	5	9
514	B:B:L198	B:B:L210	9.69	No	Yes	0	3	5
515	B:B:D212	B:B:L198	2.71	No	No	0	9	3
516	B:B:F199	B:B:W211	18.04	Yes	Yes	9	9	8
517	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
518	B:B:L210	B:B:V200	2.98	Yes	Yes	5	5	6
519	B:B:I232	B:B:V200	4.61	Yes	Yes	5	8	6
520	B:B:F234	B:B:V200	7.87	Yes	Yes	0	5	6
521	B:B:F241	B:B:V200	11.8	Yes	Yes	5	6	6
522	B:B:S201	B:B:W211	6.18	Yes	Yes	9	9	8
523	B:B:G202	B:B:I229	3.53	No	No	0	6	7
524	B:B:C204	B:B:D228	9.34	Yes	No	1	7	9
525	B:B:D205	B:B:S207	10.31	No	Yes	0	9	5
526	B:B:S207	B:B:T221	3.2	Yes	No	0	5	7
527	B:B:S207	B:B:T223	3.2	Yes	No	0	5	2
528	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
529	B:B:K209	B:B:W211	9.28	Yes	Yes	9	6	8
530	B:B:C218	B:B:K209	3.23	No	Yes	9	5	6
531	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
532	B:B:L210	B:B:R219	6.07	Yes	No	5	5	5
533	B:B:L210	B:B:Q220	2.66	Yes	Yes	5	5	7
534	B:B:L210	B:B:L255	6.92	Yes	No	5	5	6
535	B:B:C218	B:B:W211	7.84	No	Yes	9	5	8
536	B:B:D212	B:B:E215	12.99	No	No	0	9	3
537	B:B:D212	B:B:R219	14.29	No	No	0	9	5
538	B:B:E215	B:B:R214	3.49	No	No	0	3	9
539	B:B:E215	B:B:M217	2.71	No	No	0	3	3
540	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
541	B:B:Q220	B:B:R219	5.84	Yes	No	5	7	5
542	B:B:F222	B:B:Q220	5.86	Yes	Yes	5	8	7
543	B:B:D258	B:B:Q220	6.53	Yes	Yes	5	7	7
544	B:B:Q220	G:G:E22	7.65	Yes	Yes	5	7	9
545	B:B:Q220	G:G:I25	2.74	Yes	Yes	5	7	2
546	B:B:T221	G:G:E22	2.82	No	Yes	0	7	9
547	B:B:F222	B:B:F241	7.5	Yes	Yes	5	8	6
548	B:B:F222	B:B:F253	11.79	Yes	Yes	5	8	6
549	B:B:F222	B:B:L255	3.65	Yes	No	5	8	6
550	B:B:D258	B:B:F222	3.58	Yes	Yes	5	7	8
551	B:B:E260	B:B:G224	6.55	No	No	0	6	6
552	B:B:H225	B:B:I229	9.28	Yes	No	5	9	7
553	B:B:H225	B:B:T243	9.58	Yes	Yes	5	9	8
554	B:B:H225	B:B:S245	11.16	Yes	No	5	9	9
555	B:B:D247	B:B:H225	8.82	Yes	Yes	5	9	9
556	B:B:F253	B:B:H225	3.39	Yes	Yes	5	6	9
557	B:B:D247	B:B:E226	16.89	Yes	No	0	9	3
558	B:B:D247	B:B:S227	2.94	Yes	No	0	9	6
559	B:B:I229	B:B:T243	6.08	No	Yes	5	7	8
560	B:B:D246	B:B:N230	6.73	No	No	1	9	9
561	B:B:F241	B:B:I232	5.02	Yes	Yes	5	6	8
562	B:B:I232	B:B:T243	4.56	Yes	Yes	5	8	8
563	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
564	B:B:F235	B:B:P236	10.11	Yes	Yes	4	6	7
565	B:B:F235	B:B:N237	7.25	Yes	No	4	6	5
566	B:B:A240	B:B:F235	4.16	No	Yes	4	6	6
567	B:B:F235	B:B:F278	13.93	Yes	Yes	4	6	7
568	B:B:F235	B:B:G282	4.52	Yes	No	4	6	9
569	B:B:F235	G:G:L37	4.87	Yes	No	4	6	7
570	B:B:F235	G:G:Y40	3.09	Yes	Yes	4	6	6
571	B:B:F235	G:G:C41	2.79	Yes	No	0	6	7
572	B:B:F278	B:B:P236	5.78	Yes	Yes	4	7	7
573	B:B:G282	B:B:P236	4.06	No	Yes	4	9	7
574	B:B:P236	G:G:Y40	5.56	Yes	Yes	4	7	6
575	B:B:N237	B:B:N239	13.62	No	No	0	5	2
576	B:B:N237	G:G:Y40	6.98	No	Yes	4	5	6
577	B:B:N239	B:B:R256	7.23	No	No	0	2	9
578	B:B:A240	G:G:L37	3.15	No	No	4	6	7
579	B:B:F241	B:B:T243	2.59	Yes	Yes	5	6	8
580	B:B:F241	B:B:F253	13.93	Yes	Yes	5	6	6
581	B:B:F241	B:B:L255	3.65	Yes	No	5	6	6
582	B:B:A242	B:B:F278	2.77	No	Yes	4	4	7
583	B:B:A242	B:B:L285	3.15	No	Yes	4	4	6
584	B:B:F253	B:B:T243	7.78	Yes	Yes	5	6	8
585	B:B:G244	B:B:S245	3.71	No	No	0	5	9
586	B:B:G244	B:B:I273	7.05	No	No	0	5	6
587	B:B:D247	B:B:S245	8.83	Yes	No	5	9	9
588	B:B:D247	B:B:T249	10.12	Yes	No	0	9	6
589	B:B:T249	B:B:T263	3.14	No	No	0	6	1
590	B:B:S265	B:B:T249	9.59	No	No	0	2	6
591	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
592	B:B:C250	B:B:I273	6.55	No	No	0	8	6
593	B:B:E260	B:B:R251	23.26	No	No	0	6	8
594	B:B:R251	B:B:T263	11.64	No	No	0	8	1
595	B:B:L252	B:B:L261	4.15	No	No	0	7	5
596	B:B:L252	B:B:Y264	8.21	No	Yes	0	7	5
597	B:B:E260	B:B:F253	18.66	No	Yes	0	6	6
598	B:B:D254	B:B:R256	4.76	Yes	No	0	9	9
599	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
600	B:B:D254	B:B:L261	5.43	Yes	No	0	9	5
601	B:B:D254	G:G:A33	6.18	Yes	No	0	9	7
602	B:B:R256	G:G:D36	7.15	No	No	0	9	5
603	B:B:D258	G:G:R27	19.06	Yes	Yes	5	7	8
604	B:B:Q259	G:G:V30	2.87	No	No	0	6	8
605	B:B:L261	G:G:V30	2.98	No	No	0	5	8
606	B:B:M262	B:B:Y264	11.97	Yes	Yes	4	4	5
607	B:B:A302	B:B:M262	3.22	No	Yes	4	2	4
608	B:B:L285	B:B:Y264	4.69	Yes	Yes	4	6	5
609	B:B:W297	B:B:Y264	6.75	Yes	Yes	4	8	5
610	B:B:A299	B:B:Y264	2.67	No	Yes	0	5	5
611	B:B:A302	B:B:Y264	2.67	No	Yes	4	2	5
612	B:B:H266	B:B:N268	2.55	No	No	0	4	4
613	B:B:H266	B:B:I269	2.65	No	Yes	4	4	4
614	B:B:H266	B:B:R304	14.67	No	Yes	4	4	5
615	B:B:I269	B:B:Y289	3.63	Yes	Yes	4	4	7
616	B:B:I269	B:B:R304	2.51	Yes	Yes	4	4	5
617	B:B:C271	B:B:D290	9.34	No	No	0	5	6
618	B:B:C271	B:B:D291	6.22	No	No	0	5	8
619	B:B:D290	B:B:G272	5.03	No	No	0	6	4
620	B:B:I273	B:B:Y289	6.04	No	Yes	0	6	7
621	B:B:R314	B:B:T274	5.17	Yes	No	0	8	8
622	B:B:L318	B:B:S275	3	Yes	No	0	6	8
623	B:B:L285	B:B:V276	4.47	Yes	No	0	6	6
624	B:B:L318	B:B:S277	3	Yes	No	0	6	5
625	B:B:F278	B:B:G282	3.01	Yes	No	4	7	9
626	B:B:F278	B:B:L285	9.74	Yes	Yes	4	7	6
627	B:B:S279	B:B:S281	3.26	No	Yes	13	9	9
628	B:B:L284	B:B:S279	6.01	No	No	0	5	9
629	B:B:S279	G:G:D48	8.83	No	Yes	13	9	9
630	B:B:R283	B:B:S281	2.64	Yes	Yes	13	9	9
631	B:B:S281	G:G:D48	10.31	Yes	Yes	13	9	9
632	B:B:S281	G:G:L51	3	Yes	Yes	13	9	6
633	B:B:D298	B:B:R283	11.91	No	Yes	13	9	9
634	B:B:L300	B:B:R283	8.5	Yes	Yes	13	6	9
635	B:B:R283	G:G:L51	7.29	Yes	Yes	13	9	6
636	B:B:L284	B:B:V296	5.96	No	No	0	5	5
637	B:B:L286	B:B:V296	5.96	No	No	0	7	5
638	B:B:L286	B:B:L318	2.77	No	Yes	0	7	6
639	B:B:A287	B:B:Y289	4	No	Yes	4	6	7
640	B:B:A287	B:B:W297	2.59	No	Yes	4	6	8
641	B:B:C294	B:B:G288	3.92	No	No	0	5	7
642	B:B:G288	B:B:V315	3.68	No	No	0	7	7
643	B:B:D291	B:B:Y289	3.45	No	Yes	0	8	7
644	B:B:N295	B:B:Y289	12.79	Yes	Yes	4	6	7
645	B:B:W297	B:B:Y289	5.79	Yes	Yes	4	8	7
646	B:B:D290	B:B:R314	13.1	No	Yes	0	6	8
647	B:B:D291	B:B:N293	12.12	No	No	0	8	5
648	B:B:N293	B:B:N295	5.45	No	Yes	4	5	6
649	B:B:N293	B:B:V307	4.43	No	Yes	4	5	3
650	B:B:N295	B:B:W297	6.78	Yes	Yes	4	6	8
651	B:B:N295	B:B:R304	9.64	Yes	Yes	4	6	5
652	B:B:N295	B:B:V307	2.96	Yes	Yes	4	6	3
653	B:B:R304	B:B:W297	4	Yes	Yes	4	5	8
654	B:B:D298	B:B:L300	2.71	No	Yes	13	9	6
655	B:B:D298	B:B:K301	11.06	No	Yes	0	9	5
656	B:B:L300	G:G:M38	2.83	Yes	No	13	6	4
657	B:B:L300	G:G:C41	6.35	Yes	No	0	6	7
658	B:B:D303	B:B:K301	8.3	No	Yes	0	2	5
659	B:B:L308	B:B:W339	22.78	No	Yes	0	7	9
660	B:B:G310	B:B:K337	3.49	No	Yes	14	5	6
661	B:B:G310	B:B:W339	2.81	No	Yes	14	5	9
662	B:B:H311	B:B:V315	4.15	Yes	No	14	9	7
663	B:B:H311	B:B:T329	6.85	Yes	Yes	14	9	8
664	B:B:H311	B:B:S331	13.95	Yes	No	14	9	9
665	B:B:D333	B:B:H311	11.35	Yes	Yes	14	9	9
666	B:B:H311	B:B:K337	10.48	Yes	Yes	14	9	6
667	B:B:D312	B:B:D333	11.98	No	Yes	0	5	9
668	B:B:N313	B:B:W332	9.04	No	Yes	0	7	9
669	B:B:R314	B:B:W332	24.99	Yes	Yes	1	8	9
670	B:B:T329	B:B:V315	3.17	Yes	No	14	8	7
671	B:B:C317	B:B:S316	3.44	No	No	0	7	9
672	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
673	B:B:L318	B:B:V327	2.98	Yes	No	0	6	6
674	B:B:L318	B:B:T329	2.95	Yes	Yes	0	6	8
675	B:B:V320	B:B:V327	3.21	No	No	0	7	6
676	B:B:A326	B:B:T321	3.36	No	No	0	7	7
677	B:B:D323	B:B:M325	2.77	No	Yes	0	7	5
678	B:B:G324	G:G:P49	4.06	No	No	0	9	7
679	B:B:M325	G:G:P49	6.71	Yes	No	0	5	7
680	B:B:M325	G:G:E58	2.71	Yes	No	0	5	5
681	B:B:M325	G:G:P60	3.35	Yes	Yes	0	5	9
682	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
683	B:B:V327	B:B:W339	3.68	No	Yes	0	6	9
684	B:B:T329	B:B:W339	9.7	Yes	Yes	14	8	9
685	B:B:D333	B:B:S331	11.78	Yes	No	14	9	9
686	B:B:D333	B:B:F335	5.97	Yes	Yes	0	9	4
687	B:B:F335	B:B:S334	2.64	Yes	No	0	4	4
688	B:B:F335	R:R:K132	2.48	Yes	No	0	4	6
689	B:B:K337	B:B:W339	9.28	Yes	Yes	14	6	9
690	B:B:I338	G:G:F61	3.77	No	Yes	3	5	8
691	B:B:N340	G:G:N59	9.54	No	Yes	3	9	9
692	G:G:A10	G:G:R13	4.15	No	No	0	2	6
693	G:G:L15	G:G:L19	5.54	No	No	0	2	9
694	G:G:L19	G:G:Q18	2.66	No	No	0	9	9
695	G:G:E22	G:G:Q18	3.82	Yes	No	0	9	9
696	G:G:M21	G:G:N24	5.61	No	No	0	1	1
697	G:G:E22	G:G:I25	2.73	Yes	Yes	5	9	2
698	G:G:E22	G:G:R27	4.65	Yes	Yes	5	9	8
699	G:G:I25	G:G:N24	2.83	Yes	No	0	2	1
700	G:G:I25	G:G:R27	10.02	Yes	Yes	5	2	8
701	G:G:I28	G:G:K32	2.91	No	No	0	4	5
702	G:G:H44	G:G:Y40	16.33	No	Yes	0	6	6
703	G:G:A43	G:G:H44	2.93	No	No	0	4	6
704	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
705	G:G:D48	G:G:L50	2.71	Yes	No	0	9	9
706	G:G:D48	G:G:L51	5.43	Yes	Yes	13	9	6
707	G:G:P55	G:G:V54	5.3	No	No	0	5	6
708	G:G:E58	G:G:V54	2.85	No	No	0	5	6
709	G:G:N59	G:G:V54	2.96	Yes	No	0	9	6
710	G:G:N59	G:G:P60	6.52	Yes	Yes	3	9	9
711	G:G:F61	G:G:N59	6.04	Yes	Yes	3	8	9
712	G:G:F61	G:G:P60	5.78	Yes	Yes	3	8	9
713	R:R:L258	R:R:S42	9.01	Yes	No	0	5	6
714	R:R:A92	R:R:F43	4.16	No	Yes	19	7	6
715	R:R:F43	R:R:Y95	3.09	Yes	No	0	6	5
716	R:R:F43	R:R:L96	7.31	Yes	No	0	6	5
717	R:R:E347	R:R:F43	8.16	No	Yes	19	2	6
718	R:R:F43	R:R:Y350	10.32	Yes	Yes	0	6	4
719	R:R:L44	R:R:R46	6.07	No	Yes	20	4	6
720	R:R:E260	R:R:L44	5.3	No	No	20	2	4
721	R:R:L263	R:R:L44	4.15	No	No	0	4	4
722	R:R:F87	R:R:R46	6.41	No	Yes	0	2	6
723	R:R:E260	R:R:R46	12.79	No	Yes	20	2	6
724	R:R:R46	R:R:T343	2.59	Yes	No	0	6	6
725	R:R:F87	R:R:N47	4.83	No	No	0	2	6
726	R:R:A86	R:R:P247	3.74	No	No	0	5	1
727	R:R:I88	R:R:V246	3.07	No	Yes	0	4	3
728	R:R:D91	R:R:S89	8.83	No	No	0	3	6
729	R:R:E90	R:R:S93	7.19	No	No	0	4	2
730	R:R:D91	R:R:E347	2.6	No	No	0	3	2
731	R:R:A92	R:R:E347	4.53	No	No	19	7	2
732	R:R:A348	R:R:Y95	2.67	No	No	0	1	5
733	R:R:F351	R:R:Y95	19.6	Yes	No	0	1	5
734	R:R:L96	R:R:S166	6.01	No	Yes	0	5	4
735	R:R:D256	R:R:L96	2.71	Yes	No	0	4	5
736	R:R:S98	R:R:W100	4.94	No	No	0	7	5
737	R:R:F104	R:R:W100	4.01	No	No	0	5	5
738	R:R:F351	R:R:W100	5.01	Yes	No	0	1	5
739	R:R:L101	R:R:Y162	3.52	No	Yes	0	4	5
740	R:R:F351	R:R:L101	3.65	Yes	No	0	1	4
741	R:R:L101	R:R:L354	4.15	No	No	0	4	4
742	R:R:L103	R:R:T102	4.42	No	No	0	4	3
743	R:R:F104	R:R:V105	2.62	No	Yes	0	5	5
744	R:R:F104	R:R:V108	7.87	No	No	0	5	5
745	R:R:P106	R:R:V105	3.53	No	Yes	8	6	5
746	R:R:V105	R:R:Y162	5.05	Yes	Yes	8	5	5
747	R:R:C358	R:R:V105	6.83	No	Yes	0	5	5
748	R:R:P106	R:R:Y162	4.17	No	Yes	8	6	5
749	R:R:F163	R:R:P106	17.34	No	No	0	4	6
750	R:R:L155	R:R:Y109	8.21	No	Yes	0	8	7
751	R:R:V357	R:R:Y109	2.52	No	Yes	0	6	7
752	R:R:C358	R:R:Y109	9.41	No	Yes	0	5	7
753	R:R:S361	R:R:Y109	5.09	No	Yes	0	7	7
754	R:R:G111	R:R:T110	3.64	No	No	0	5	4
755	R:R:I159	R:R:T110	7.6	No	No	0	7	4
756	R:R:S361	R:R:V112	4.85	No	No	0	7	7
757	R:R:I362	R:R:V112	3.07	No	No	2	4	7
758	R:R:C365	R:R:V112	5.12	Yes	No	2	8	7
759	R:R:F113	R:R:L117	3.65	No	Yes	21	7	6
760	R:R:F113	R:R:V152	2.62	No	No	21	7	6
761	R:R:F113	R:R:P156	7.22	No	No	0	7	9
762	R:R:C365	R:R:V115	3.42	Yes	No	0	8	5
763	R:R:N120	R:R:S116	4.47	Yes	Yes	0	9	8
764	R:R:S116	R:R:V152	3.23	Yes	No	0	8	6
765	R:R:C364	R:R:S116	3.44	No	Yes	0	8	8
766	R:R:C365	R:R:S116	3.44	Yes	Yes	0	8	8
767	R:R:L117	R:R:P118	3.28	Yes	No	0	6	4
768	R:R:L117	R:R:V152	2.98	Yes	No	21	6	6
769	R:R:L119	R:R:P368	4.93	No	No	0	7	9
770	R:R:D148	R:R:N120	10.77	No	Yes	0	9	9
771	R:R:N120	R:R:P368	9.77	Yes	No	2	9	9
772	R:R:N120	R:R:Y372	3.49	Yes	Yes	2	9	6
773	R:R:M122	R:R:Y373	3.59	No	No	0	5	7
774	R:R:A123	R:R:Y372	5.34	No	Yes	0	8	6
775	R:R:A123	R:R:Y373	2.67	No	No	0	8	7
776	R:R:I124	R:R:L142	2.85	Yes	No	0	7	6
777	R:R:L129	R:R:V125	2.98	No	No	0	4	3
778	R:R:F127	R:R:V126	2.62	Yes	No	0	6	7
779	R:R:K130	R:R:V126	3.04	No	No	0	5	7
780	R:R:F127	R:R:V138	3.93	Yes	No	0	6	7
781	R:R:F127	R:R:M141	9.95	Yes	No	2	6	8
782	R:R:F127	R:R:Y372	6.19	Yes	Yes	2	6	6
783	R:R:I128	R:R:L129	2.85	No	No	0	4	4
784	R:R:C378	R:R:K130	4.85	No	No	0	8	5
785	R:R:E377	R:R:M131	5.41	No	No	0	6	5
786	R:R:K132	R:R:K134	7.18	No	No	0	6	5
787	R:R:V133	R:R:V139	3.21	No	No	0	6	7
788	R:R:K134	R:R:K135	5.75	No	No	0	5	7
789	R:R:L216	R:R:P136	6.57	No	No	0	2	6
790	R:R:H143	R:R:V139	2.77	Yes	No	0	9	7
791	R:R:A219	R:R:V139	5.09	No	No	0	7	7
792	R:R:V195	R:R:Y140	6.31	No	Yes	22	7	7
793	R:R:I196	R:R:Y140	4.84	No	Yes	0	9	7
794	R:R:D199	R:R:Y140	6.9	No	Yes	0	8	7
795	R:R:A219	R:R:Y140	5.34	No	Yes	0	7	7
796	R:R:T222	R:R:Y140	2.5	No	Yes	22	5	7
797	R:R:C223	R:R:Y140	4.03	No	Yes	0	7	7
798	R:R:M141	R:R:Y372	7.18	No	Yes	2	8	6
799	R:R:H143	R:R:L192	3.86	Yes	No	0	9	7
800	R:R:C223	R:R:H143	16.22	No	Yes	0	7	9
801	R:R:H143	R:R:W227	7.41	Yes	No	0	9	9
802	R:R:L144	R:R:L192	4.15	Yes	No	0	9	7
803	R:R:L144	R:R:M193	2.83	Yes	Yes	2	9	8
804	R:R:L144	R:R:Y371	3.52	Yes	Yes	2	9	9
805	R:R:L144	R:R:Y372	8.21	Yes	Yes	2	9	6
806	R:R:A145	R:R:Y372	4	No	Yes	0	8	6
807	R:R:A147	R:R:W227	2.59	No	No	0	8	9
808	R:R:D148	R:R:S189	2.94	No	No	0	9	9
809	R:R:C364	R:R:D148	9.34	No	No	0	8	9
810	R:R:L150	R:R:N185	6.87	No	No	0	6	8
811	R:R:F151	R:R:F182	7.5	Yes	Yes	2	7	6
812	R:R:F151	R:R:N185	4.83	Yes	No	0	7	8
813	R:R:F151	R:R:M186	4.98	Yes	No	2	7	7
814	R:R:F151	R:R:S361	5.28	Yes	No	0	7	7
815	R:R:C364	R:R:F151	2.79	No	Yes	0	8	7
816	R:R:F157	R:R:F170	5.36	No	Yes	0	6	7
817	R:R:F157	R:R:V178	5.24	No	No	0	6	5
818	R:R:F182	R:R:K158	14.89	Yes	No	0	6	6
819	R:R:F163	R:R:I159	2.51	No	No	0	4	7
820	R:R:F170	R:R:S160	2.64	Yes	No	0	7	4
821	R:R:Y161	R:R:Y162	11.91	Yes	Yes	8	5	5
822	R:R:S166	R:R:Y161	5.09	Yes	Yes	8	4	5
823	R:R:W168	R:R:Y161	9.65	Yes	Yes	8	9	5
824	R:R:T253	R:R:Y161	4.99	Yes	Yes	8	3	5
825	R:R:D256	R:R:Y161	10.34	Yes	Yes	8	4	5
826	R:R:D256	R:R:Y162	5.75	Yes	Yes	8	4	5
827	R:R:D167	R:R:S164	2.94	No	No	0	4	4
828	R:R:G165	R:R:S166	3.71	No	Yes	0	4	4
829	R:R:I251	R:R:S166	3.1	Yes	Yes	8	2	4
830	R:R:S166	R:R:T253	3.2	Yes	Yes	8	4	3
831	R:R:F170	R:R:W168	20.04	Yes	Yes	8	7	9
832	R:R:G171	R:R:W168	2.81	No	Yes	0	8	9
833	R:R:L174	R:R:W168	3.42	No	Yes	8	5	9
834	R:R:C175	R:R:W168	10.45	No	Yes	8	9	9
835	R:R:C254	R:R:W168	14.37	No	Yes	8	9	9
836	R:R:F170	R:R:Q169	15.23	Yes	No	0	7	2
837	R:R:F170	R:R:L174	3.65	Yes	No	8	7	5
838	R:R:E173	R:R:G171	3.27	No	No	0	2	8
839	R:R:E241	R:R:S172	11.5	No	No	8	4	2
840	R:R:S172	R:R:T243	4.8	No	Yes	8	2	4
841	R:R:E173	R:R:L174	3.98	No	No	0	2	5
842	R:R:C175	R:R:T243	5.07	No	Yes	8	9	4
843	R:R:C175	R:R:C254	7.28	No	No	8	9	9
844	R:R:L238	R:R:R176	6.07	No	No	0	4	7
845	R:R:A181	R:R:F177	2.77	No	No	0	5	4
846	R:R:T179	R:R:Y183	2.5	No	Yes	2	5	5
847	R:R:L237	R:R:T179	4.42	No	No	2	4	5
848	R:R:H255	R:R:T179	8.21	Yes	No	2	4	5
849	R:R:A180	R:R:V234	3.39	No	No	0	6	6
850	R:R:A180	R:R:L238	3.15	No	No	0	6	4
851	R:R:F182	R:R:Y183	4.13	Yes	Yes	2	6	5
852	R:R:F182	R:R:M186	2.49	Yes	No	2	6	7
853	R:R:F182	R:R:V357	2.62	Yes	No	0	6	6
854	R:R:L237	R:R:Y183	3.52	No	Yes	2	4	5
855	R:R:F271	R:R:Y183	8.25	Yes	Yes	0	5	5
856	R:R:Y183	R:R:Y353	4.96	Yes	Yes	0	5	5
857	R:R:C184	R:R:I231	3.27	No	No	0	5	3
858	R:R:C184	R:R:V234	3.42	No	No	0	5	6
859	R:R:M186	R:R:Y187	9.58	No	Yes	2	7	8
860	R:R:I190	R:R:Y187	3.63	Yes	Yes	2	7	8
861	R:R:F274	R:R:Y187	17.54	Yes	Yes	2	5	8
862	R:R:F278	R:R:Y187	5.16	Yes	Yes	2	6	8
863	R:R:N330	R:R:Y187	9.3	Yes	Yes	0	8	8
864	R:R:A188	R:R:W227	3.89	No	No	0	7	9
865	R:R:F279	R:R:I190	2.51	Yes	Yes	2	8	7
866	R:R:F322	R:R:I190	2.51	Yes	Yes	2	9	7
867	R:R:F326	R:R:I190	11.3	Yes	Yes	2	9	7
868	R:R:I226	R:R:L191	4.28	No	No	0	7	5
869	R:R:I226	R:R:L192	2.85	No	No	0	7	7
870	R:R:F322	R:R:M193	4.98	Yes	Yes	2	9	8
871	R:R:F326	R:R:M193	3.73	Yes	Yes	2	9	8
872	R:R:D367	R:R:M193	5.54	No	Yes	2	9	8
873	R:R:M193	R:R:Y371	8.38	Yes	Yes	2	8	9
874	R:R:P282	R:R:T194	6.99	No	Yes	0	9	7
875	R:R:I285	R:R:T194	3.04	No	Yes	0	6	7
876	R:R:S286	R:R:T194	3.2	Yes	Yes	2	8	7
877	R:R:F322	R:R:T194	2.59	Yes	Yes	2	9	7
878	R:R:T222	R:R:V195	3.17	No	No	22	5	7
879	R:R:I226	R:R:V195	3.07	No	No	0	7	7
880	R:R:I196	R:R:R200	5.01	No	Yes	0	9	9
881	R:R:S197	R:R:S286	6.52	No	Yes	2	9	8
882	R:R:C289	R:R:S197	5.16	No	No	0	7	9
883	R:R:S197	R:R:Y290	5.09	No	Yes	2	9	8
884	R:R:I198	R:R:I285	2.94	No	No	0	6	6
885	R:R:C289	R:R:I198	3.27	No	No	0	7	6
886	R:R:D199	R:R:R214	9.53	No	Yes	0	8	7
887	R:R:R200	R:R:Y290	7.2	Yes	Yes	2	9	8
888	R:R:R200	R:R:V318	2.62	Yes	Yes	2	9	8
889	R:R:R200	R:R:Y371	6.17	Yes	Yes	2	9	9
890	R:R:F201	R:R:L202	3.65	Yes	No	0	8	6
891	R:R:F201	R:R:V205	11.8	Yes	No	23	8	7
892	R:R:F201	R:R:Y206	4.13	Yes	No	23	8	7
893	R:R:C289	R:R:F201	5.59	No	Yes	0	7	8
894	R:R:F201	R:R:S292	5.28	Yes	No	0	8	3
895	R:R:F201	R:R:I293	2.51	Yes	No	0	8	8
896	R:R:L202	R:R:W213	3.42	No	No	0	6	3
897	R:R:A203	R:R:R214	6.91	No	Yes	0	8	7
898	R:R:V205	R:R:Y206	3.79	No	No	23	7	7
899	R:R:Q209	R:R:Y206	3.38	No	No	0	4	7
900	R:R:M208	R:R:Q209	4.08	Yes	No	0	4	4
901	R:R:Q209	R:R:W213	10.95	No	No	0	4	3
902	R:R:R218	R:R:T215	12.94	No	No	0	4	6
903	R:R:F278	R:R:L229	3.65	Yes	No	0	6	4
904	R:R:F274	R:R:G233	3.01	Yes	No	0	5	5
905	R:R:V234	R:R:Y270	2.52	No	Yes	0	6	5
906	R:R:P236	R:R:V235	3.53	No	No	0	7	4
907	R:R:L239	R:R:V235	2.98	No	No	0	4	4
908	R:R:P236	R:R:Y266	4.17	No	No	0	7	4
909	R:R:P236	R:R:Y270	13.91	No	Yes	0	7	5
910	R:R:L237	R:R:Y270	4.69	No	Yes	0	4	5
911	R:R:K240	R:R:Q242	2.71	No	Yes	2	4	4
912	R:R:K240	R:R:Y266	13.14	No	No	2	4	4
913	R:R:K240	R:R:Y267	4.78	No	Yes	2	4	4
914	R:R:E241	R:R:T243	4.23	No	Yes	8	4	4
915	R:R:H255	R:R:Q242	3.71	Yes	Yes	2	4	4
916	R:R:L258	R:R:Q242	2.66	Yes	Yes	2	5	4
917	R:R:Q242	R:R:Y267	9.02	Yes	Yes	2	4	4
918	R:R:I244	R:R:V246	3.07	No	Yes	0	2	3
919	R:R:Q245	R:R:T252	4.25	No	No	0	1	5
920	R:R:I251	R:R:V246	3.07	Yes	Yes	0	2	3
921	R:R:V246	R:R:V257	4.81	Yes	No	0	3	3
922	R:R:L249	R:R:N250	2.75	No	No	0	4	5
923	R:R:I251	R:R:L249	2.85	Yes	No	0	2	4
924	R:R:I251	R:R:T253	3.04	Yes	Yes	8	2	3
925	R:R:D256	R:R:T253	4.34	Yes	Yes	8	4	3
926	R:R:T253	R:R:V257	6.35	Yes	No	0	3	3
927	R:R:H255	R:R:L258	5.14	Yes	Yes	2	4	5
928	R:R:F271	R:R:H255	4.53	Yes	Yes	0	5	4
929	R:R:L258	R:R:L263	6.92	Yes	No	0	5	4
930	R:R:L258	R:R:Y267	11.72	Yes	Yes	2	5	4
931	R:R:N259	R:R:T261	11.7	No	No	2	4	1
932	R:R:L262	R:R:N259	8.24	No	No	2	3	4
933	R:R:L262	R:R:T261	2.95	No	No	2	3	1
934	R:R:L262	R:R:Y267	3.52	No	Yes	2	3	4
935	R:R:E264	R:R:L340	3.98	No	Yes	0	4	3
936	R:R:Y266	R:R:Y267	4.96	No	Yes	2	4	4
937	R:R:F271	R:R:Y267	3.09	Yes	Yes	0	5	4
938	R:R:F271	R:R:Y270	13.41	Yes	Yes	0	5	5
939	R:R:F274	R:R:Y270	8.25	Yes	Yes	0	5	5
940	R:R:F271	R:R:Y337	22.69	Yes	No	0	5	5
941	R:R:F274	R:R:F278	7.5	Yes	Yes	2	5	6
942	R:R:N330	R:R:S275	5.96	Yes	No	0	8	5
943	R:R:L333	R:R:S275	4.5	No	No	0	5	5
944	R:R:I334	R:R:S275	3.1	No	No	0	5	5
945	R:R:F278	R:R:V277	5.24	Yes	No	0	6	4
946	R:R:F279	R:R:F280	12.86	Yes	No	0	8	5
947	R:R:F279	R:R:L283	6.09	Yes	No	0	8	6
948	R:R:F279	R:R:F326	3.22	Yes	Yes	2	8	9
949	R:R:F279	R:R:G327	4.52	Yes	No	0	8	5
950	R:R:F279	R:R:N330	24.17	Yes	Yes	0	8	8
951	R:R:F280	R:R:I334	2.51	No	No	0	5	5
952	R:R:P282	R:R:V281	3.53	No	No	0	9	5
953	R:R:I285	R:R:V281	3.07	No	No	0	6	5
954	R:R:F322	R:R:L283	3.65	Yes	No	0	9	6
955	R:R:S286	R:R:Y290	2.54	Yes	Yes	2	8	8
956	R:R:F322	R:R:S286	2.64	Yes	Yes	2	9	8
957	R:R:F319	R:R:T287	6.49	No	No	0	8	4
958	R:R:S315	R:R:Y290	2.54	No	Yes	0	7	8
959	R:R:V318	R:R:Y290	6.31	Yes	Yes	2	8	8
960	R:R:F319	R:R:Y290	7.22	No	Yes	0	8	8
961	R:R:I294	R:R:L312	4.28	No	No	0	4	5
962	R:R:I294	R:R:S315	4.64	No	No	0	4	7
963	R:R:K308	R:R:L297	8.46	No	Yes	0	6	8
964	R:R:A311	R:R:L297	3.15	No	Yes	18	7	8
965	R:R:L297	R:R:L312	2.77	Yes	No	0	8	5
966	R:R:L312	R:R:S298	3	No	No	0	5	4
967	R:R:N304	R:R:R305	6.03	No	No	0	4	3
968	R:R:K308	R:R:S306	3.06	No	No	0	6	2
969	R:R:K307	R:R:S309	3.06	No	No	0	4	4
970	R:R:F313	R:R:S309	2.64	No	No	0	5	4
971	R:R:L314	R:R:R310	3.64	No	No	0	7	7
972	R:R:I370	R:R:L314	2.85	Yes	No	0	7	7
973	R:R:A374	R:R:L314	3.15	No	No	0	6	7
974	R:R:I370	R:R:V318	6.14	Yes	Yes	2	7	8
975	R:R:V318	R:R:Y371	5.05	Yes	Yes	2	8	9
976	R:R:F319	R:R:I323	6.28	No	No	0	8	5
977	R:R:I321	R:R:I366	7.36	No	No	2	6	7
978	R:R:C325	R:R:F326	5.59	Yes	Yes	2	8	9
979	R:R:C325	R:R:S363	6.89	Yes	No	2	8	9
980	R:R:F326	R:R:S360	2.64	Yes	No	0	9	8
981	R:R:F326	R:R:S363	5.28	Yes	No	2	9	9
982	R:R:G327	R:R:P328	4.06	No	No	0	5	9
983	R:R:N330	R:R:T329	2.92	Yes	Yes	0	8	6
984	R:R:T329	R:R:Y353	4.99	Yes	Yes	0	6	5
985	R:R:C356	R:R:T329	5.07	No	Yes	0	6	6
986	R:R:S360	R:R:T329	3.2	No	Yes	0	8	6
987	R:R:A352	R:R:L332	3.15	No	No	0	5	5
988	R:R:C356	R:R:L332	3.17	No	No	0	6	5
989	R:R:L333	R:R:Y353	16.41	No	Yes	0	5	5
990	R:R:A335	R:R:F339	2.77	No	No	0	5	3
991	R:R:H336	R:R:Y337	14.16	Yes	No	0	4	5
992	R:R:H336	R:R:L340	3.86	Yes	Yes	24	4	3
993	R:R:H336	R:R:T346	4.11	Yes	No	24	4	1
994	R:R:H336	R:R:Y350	15.24	Yes	Yes	0	4	4
995	R:R:F339	R:R:S338	11.89	No	No	0	3	4
996	R:R:L340	R:R:T346	2.95	Yes	No	24	3	1
997	R:R:H342	R:R:S344	4.18	No	No	0	2	3
998	R:R:H342	R:R:T345	17.8	No	No	0	2	1
999	R:R:Y350	R:R:Y353	8.94	Yes	Yes	0	4	5
1000	R:R:L354	R:R:Y350	11.72	No	Yes	0	4	4
1001	R:R:F351	R:R:L355	4.87	Yes	No	0	1	5
1002	R:R:V357	R:R:Y353	8.83	No	Yes	0	6	5
1003	R:R:C365	R:R:I362	3.27	Yes	No	2	8	4
1004	R:R:D367	R:R:Y371	3.45	No	Yes	2	9	9
1005	R:R:P368	R:R:Y372	4.17	No	Yes	2	9	6
1006	R:R:I370	R:R:Y371	3.63	Yes	Yes	2	7	9
1007	R:R:Y371	R:R:Y372	2.98	Yes	Yes	2	9	6
1008	R:R:E377	R:R:S375	5.75	No	No	0	6	7
1009	B:B:L7	G:G:R13	2.43	Yes	No	0	8	6
1010	B:B:N340	B:B:R48	2.41	No	No	3	9	7
1011	B:B:R48	G:G:N59	2.41	No	Yes	3	7	9
1012	A:A:F191	A:A:Q333	2.34	Yes	No	11	5	5
1013	A:A:F336	A:A:Q333	2.34	Yes	No	11	8	5
1014	R:R:E377	R:R:F127	2.33	No	Yes	0	6	6
1015	A:A:F354	R:R:R310	2.14	No	No	0	5	7
1016	A:A:C224	A:A:G45	1.96	Yes	No	0	7	9
1017	B:B:C317	B:B:G330	1.96	No	No	0	7	5
1018	A:A:A30	A:A:G27	1.95	No	No	0	3	5
1019	B:B:A106	B:B:P107	1.87	No	No	0	6	6
1020	R:R:A219	R:R:P136	1.87	No	No	0	7	6
1021	R:R:G94	R:R:S93	1.86	No	No	0	4	2
1022	R:R:G165	R:R:S164	1.86	No	No	0	4	4
1023	R:R:G217	R:R:S220	1.86	No	No	0	4	3
1024	A:A:G202	A:A:V201	1.84	No	Yes	0	9	9
1025	B:B:G306	B:B:V296	1.84	No	No	0	4	5
1026	B:B:G306	B:B:V307	1.84	No	Yes	0	4	3
1027	R:R:G111	R:R:V114	1.84	No	No	0	5	5
1028	B:B:G174	B:B:T173	1.82	No	No	0	4	5
1029	B:B:G182	B:B:T181	1.82	No	No	0	6	2
1030	B:B:G185	B:B:T184	1.82	No	No	0	5	3
1031	R:R:G94	R:R:T97	1.82	No	No	0	4	5
1032	R:R:G165	R:R:T102	1.82	No	No	0	4	3
1033	R:R:G217	R:R:T215	1.82	No	No	0	4	6
1034	A:A:C351	R:R:A137	1.81	Yes	No	0	4	7
1035	B:B:A60	B:B:C103	1.81	No	Yes	0	7	8
1036	R:R:A230	R:R:C184	1.81	No	No	0	8	5
1037	R:R:P247	R:R:V246	1.77	No	Yes	0	1	3
1038	R:R:G248	R:R:I251	1.76	No	Yes	0	3	2
1039	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1040	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1041	B:B:G324	B:B:K280	1.74	No	No	0	9	1
1042	A:A:L23	B:B:G53	1.71	Yes	No	0	6	9
1043	A:A:G27	B:B:L55	1.71	No	No	0	5	6
1044	A:A:G40	A:A:L39	1.71	No	No	0	9	9
1045	B:B:A28	G:G:S31	1.71	No	No	0	4	9
1046	B:B:G77	B:B:L95	1.71	No	Yes	0	8	8
1047	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
1048	R:R:C296	R:R:V205	1.71	No	No	0	5	7
1049	R:R:G217	R:R:L216	1.71	No	No	0	4	2
1050	A:A:G183	B:B:N119	1.7	No	No	0	9	9
1051	B:B:A11	G:G:V16	1.7	No	No	0	5	7
1052	B:B:A305	B:B:V40	1.7	No	No	0	4	3
1053	B:B:A231	B:B:V276	1.7	No	No	0	5	6
1054	B:B:A309	B:B:V307	1.7	No	Yes	0	3	3
1055	R:R:A181	R:R:V154	1.7	No	No	0	5	6
1056	A:A:I285	A:A:P282	1.69	No	No	0	3	5
1057	A:A:A203	A:A:T182	1.68	No	No	0	9	7
1058	A:A:E216	A:A:G217	1.64	No	No	0	7	5
1059	B:B:C271	B:B:I270	1.64	No	No	0	5	3
1060	R:R:E264	R:R:G265	1.64	No	No	0	4	3
1061	R:R:C325	R:R:I321	1.64	Yes	No	2	8	6
1062	R:R:C325	R:R:I366	1.64	Yes	No	2	8	7
1063	R:R:C365	R:R:I366	1.64	Yes	No	2	8	7
1064	R:R:S98	R:R:S99	1.63	No	No	0	7	5
1065	A:A:I19	B:B:A92	1.62	No	No	0	9	6
1066	A:A:C325	A:A:K330	1.62	No	No	0	7	4
1067	B:B:I33	G:G:A34	1.62	No	No	0	3	6
1068	B:B:A92	B:B:I80	1.62	No	Yes	0	6	8
1069	B:B:A140	B:B:I120	1.62	No	No	0	5	6
1070	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
1071	G:G:A10	G:G:I9	1.62	No	No	0	2	2
1072	R:R:S107	R:R:V108	1.62	No	No	0	5	5
1073	R:R:A145	R:R:I124	1.62	No	Yes	0	8	7
1074	R:R:S292	R:R:V288	1.62	No	No	0	3	4
1075	R:R:A317	R:R:I370	1.62	No	Yes	0	4	7
1076	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1077	G:G:A10	G:G:K14	1.61	No	No	0	2	4
1078	A:A:V335	A:A:V339	1.6	No	No	0	8	8
1079	B:B:S31	B:B:T29	1.6	No	No	0	1	3
1080	R:R:V125	R:R:V126	1.6	No	No	0	3	7
1081	A:A:T182	A:A:V185	1.59	No	No	0	7	5
1082	A:A:T187	A:A:V185	1.59	No	No	0	6	5
1083	R:R:T287	R:R:V291	1.59	No	No	0	4	3
1084	B:B:L7	G:G:A12	1.58	Yes	No	0	8	5
1085	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
1086	R:R:A86	R:R:L45	1.58	No	No	0	5	6
1087	R:R:A268	R:R:L340	1.58	No	Yes	0	3	3
1088	A:A:C254	A:A:N255	1.57	Yes	No	0	5	8
1089	B:B:T165	B:B:T181	1.57	Yes	No	1	7	2
1090	B:B:T177	B:B:T178	1.57	No	No	0	4	4
1091	B:B:T179	B:B:T181	1.57	No	No	1	4	2
1092	R:R:T243	R:R:T252	1.57	Yes	No	0	4	5
1093	R:R:A181	R:R:N185	1.56	No	No	0	5	8
1094	R:R:I88	R:R:S93	1.55	No	No	0	4	2
1095	R:R:I334	R:R:S338	1.55	No	No	0	5	4
1096	R:R:I284	R:R:V288	1.54	No	No	0	3	4
1097	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
1098	R:R:C378	R:R:Q379	1.53	No	No	0	8	8
1099	A:A:K51	A:A:V50	1.52	No	No	0	9	6
1100	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
1101	B:B:A28	B:B:Q32	1.52	No	No	0	4	1
1102	R:R:I124	R:R:T146	1.52	Yes	No	0	7	5
1103	A:A:K270	A:A:T48	1.5	No	No	0	9	9
1104	R:R:L117	R:R:V149	1.49	Yes	No	0	6	7
1105	R:R:L150	R:R:V149	1.49	No	No	0	6	7
1106	R:R:I121	R:R:I124	1.47	No	Yes	0	4	7
1107	A:A:I19	A:A:M18	1.46	No	No	0	9	4
1108	B:B:N125	B:B:T128	1.46	No	No	0	4	3
1109	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1110	R:R:A349	R:R:H336	1.46	No	Yes	0	4	4
1111	A:A:D261	A:A:T262	1.45	No	No	0	4	7
1112	A:A:D261	A:A:T316	1.45	No	No	0	4	3
1113	B:B:I18	B:B:K15	1.45	Yes	No	0	7	6
1114	A:A:K279	A:A:K280	1.44	No	No	0	2	1
1115	G:G:K29	G:G:K32	1.44	No	No	0	4	5
1116	A:A:I343	R:R:L211	1.43	No	No	0	7	5
1117	A:A:E308	A:A:T321	1.41	No	No	0	3	5
1118	B:B:L14	G:G:K20	1.41	No	No	0	8	6
1119	B:B:G141	B:B:W169	1.41	No	Yes	0	5	8
1120	G:G:D26	G:G:I25	1.4	No	Yes	0	1	2
1121	R:R:L119	R:R:L369	1.38	No	No	0	7	6
1122	B:B:D76	B:B:L55	1.36	Yes	No	0	9	6
1123	A:A:E28	A:A:K29	1.35	No	No	0	4	1
1124	B:B:D154	B:B:N155	1.35	Yes	No	0	6	3
1125	G:G:E17	G:G:K20	1.35	No	No	0	6	6
1126	G:G:E17	G:G:M21	1.35	No	No	0	6	1
1127	B:B:E10	B:B:L7	1.33	No	Yes	0	8	8
1128	B:B:N35	B:B:Q32	1.32	No	No	0	1	1
1129	B:B:E172	B:B:N155	1.31	No	No	0	6	3
1130	R:R:F280	R:R:V331	1.31	No	No	0	5	6
1131	A:A:D9	A:A:E8	1.3	No	No	0	4	5
1132	A:A:R32	R:R:T215	1.29	No	No	0	4	6
1133	B:B:E10	B:B:Q9	1.27	No	No	0	8	3
1134	G:G:E47	G:G:H44	1.23	No	No	0	3	6
1135	B:B:Q44	B:B:R42	1.17	No	No	0	4	2
1136	A:A:E43	A:A:R205	1.16	No	No	0	9	9
1137	R:R:F339	R:R:H342	1.13	No	No	0	3	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L23	2.9025	4	3	6
2	A:A:V34	5.79	4	11	5
3	A:A:L37	6.065	4	1	9
4	A:A:K46	7.3675	4	0	9
5	A:A:I49	2.8375	4	12	7
6	A:A:I184	4.2125	4	1	9
7	A:A:F191	8.52	4	11	5
8	A:A:L194	6.555	4	11	4
9	A:A:K197	8.172	5	1	6
10	A:A:M198	4.74	4	16	7
11	A:A:F199	8.27333	6	1	5
12	A:A:V201	5.142	5	1	9
13	A:A:Q204	5.6325	4	1	9
14	A:A:E207	3.76	4	1	9
15	A:A:R208	5.624	5	1	9
16	A:A:K210	4.59714	7	1	9
17	A:A:W211	7.36833	6	1	9
18	A:A:H213	5.326	5	1	8
19	A:A:C214	4.654	5	1	7
20	A:A:F215	5.03714	7	1	9
21	A:A:I221	4.45	4	1	8
22	A:A:I222	4.175	4	12	7
23	A:A:F223	6.49	5	7	9
24	A:A:C224	2.9025	4	12	7
25	A:A:V225	4.892	5	7	7
26	A:A:D229	6.494	5	10	8
27	A:A:Y230	10.586	5	10	8
28	A:A:D231	11.5825	4	10	9
29	A:A:L232	4.8775	4	10	8
30	A:A:S246	4.12	4	7	9
31	A:A:F250	6.82571	7	7	9
32	A:A:I253	4.3575	4	0	8
33	A:A:C254	4.225	4	7	5
34	A:A:W258	7.48833	6	1	5
35	A:A:F259	6.315	4	1	9
36	A:A:I265	3.1175	4	12	8
37	A:A:F267	3.875	8	12	9
38	A:A:N269	4.5925	4	12	9
39	A:A:F274	4.922	5	10	9
40	A:A:K277	7.905	4	10	9
41	A:A:I278	4.1725	4	10	6
42	A:A:C286	4.9725	4	0	6
43	A:A:Y287	6.14	7	7	7
44	A:A:Y290	7.64	4	0	7
45	A:A:Y296	11.2625	4	0	4
46	A:A:I303	3.62	4	7	7
47	A:A:F307	4.91333	6	7	8
48	A:A:Y320	8.498	5	17	7
49	A:A:F323	4.5925	4	0	4
50	A:A:N331	7.992	5	12	8
51	A:A:F336	5.23	6	11	8
52	A:A:N347	3.99	4	0	8
53	A:A:L348	3.458	5	18	9
54	A:A:D350	6.0875	4	2	4
55	A:A:C351	3.71	4	2	4
56	B:B:L7	2.08	4	0	8
57	B:B:I18	3.9825	4	5	7
58	B:B:L51	7.332	5	3	9
59	B:B:H54	7.90333	6	3	9
60	B:B:Y59	9.566	5	1	8
61	B:B:M61	4.8875	4	3	6
62	B:B:W63	7.03167	6	3	7
63	B:B:L70	6.66	4	3	5
64	B:B:V71	4.164	5	6	8
65	B:B:D76	5.62	5	3	9
66	B:B:L79	5.048	5	6	7
67	B:B:I80	7.998	5	3	8
68	B:B:I81	3.975	6	6	7
69	B:B:W82	10.0067	6	3	9
70	B:B:Y85	11.478	5	3	4
71	B:B:K89	6.795	6	3	9
72	B:B:H91	4.265	4	6	5
73	B:B:I93	5.02	4	6	7
74	B:B:L95	4.468	5	6	8
75	B:B:W99	6.30857	7	1	9
76	B:B:C103	3.0025	4	6	8
77	B:B:Y105	4.53	8	6	6
78	B:B:N110	6.2025	4	1	4
79	B:B:Y111	5.894	5	1	4
80	B:B:C114	4.305	4	6	8
81	B:B:L117	3.5625	4	1	9
82	B:B:I123	3.905	6	1	6
83	B:B:Y124	5.60833	6	6	6
84	B:B:L126	3.8125	4	6	5
85	B:B:V133	4.32	4	6	4
86	B:B:L139	4.8975	4	0	9
87	B:B:H142	7.345	6	1	9
88	B:B:Y145	5.27333	6	1	8
89	B:B:F151	4.38	6	1	9
90	B:B:L152	4.565	4	9	3
91	B:B:D154	5.28	4	1	6
92	B:B:I157	4.612	5	1	7
93	B:B:T159	5.895	6	1	9
94	B:B:S160	5.2275	4	0	6
95	B:B:D163	6.93	5	1	9
96	B:B:T165	4.0625	4	1	7
97	B:B:C166	3.815	4	9	8
98	B:B:W169	8.10571	7	1	8
99	B:B:I171	4.2	4	1	6
100	B:B:F180	8.25	6	9	7
101	B:B:H183	8.22	5	9	9
102	B:B:D186	4.98	4	1	9
103	B:B:V187	5.83	4	9	9
104	B:B:M188	4.86	4	1	8
105	B:B:L190	5.14	4	9	5
106	B:B:F199	7.84833	6	9	9
107	B:B:V200	6.815	4	5	6
108	B:B:S201	4.6075	4	9	9
109	B:B:C204	5.1175	4	1	7
110	B:B:S207	4.875	4	0	5
111	B:B:K209	9.6375	4	9	6
112	B:B:L210	5.664	5	5	5
113	B:B:W211	11.476	5	9	8
114	B:B:Q220	5.21333	6	5	7
115	B:B:F222	6.476	5	5	8
116	B:B:H225	7.28167	6	5	9
117	B:B:I232	4.7075	4	5	8
118	B:B:F234	5.76	4	0	5
119	B:B:F235	6.34	8	4	6
120	B:B:P236	6.3775	4	4	7
121	B:B:F241	6.75143	7	5	6
122	B:B:T243	6.118	5	5	8
123	B:B:D247	9.52	5	5	9
124	B:B:F253	11.11	5	5	6
125	B:B:D254	5.25	4	0	9
126	B:B:D258	10.865	4	5	7
127	B:B:M262	5.9475	4	4	4
128	B:B:Y264	5.85571	7	4	5
129	B:B:I269	2.6025	4	4	4
130	B:B:F278	7.046	5	4	7
131	B:B:S281	4.8025	4	13	9
132	B:B:R283	6.82	5	13	9
133	B:B:L285	5.5125	4	4	6
134	B:B:Y289	5.95	6	4	7
135	B:B:N295	7.524	5	4	6
136	B:B:W297	5.182	5	4	8
137	B:B:L300	4.365	6	13	6
138	B:B:K301	8.1	4	0	5
139	B:B:R304	7.705	4	4	5
140	B:B:V307	2.7325	4	4	3
141	B:B:H311	9.356	5	14	9
142	B:B:R314	9.93	5	1	8
143	B:B:L318	2.94	5	0	6
144	B:B:M325	3.885	4	0	5
145	B:B:T329	5.6675	4	14	8
146	B:B:W332	11.0314	7	1	9
147	B:B:D333	10.27	4	14	9
148	B:B:F335	3.8425	4	0	4
149	B:B:K337	8.815	4	14	6
150	B:B:W339	9.45667	6	14	9
151	G:G:E22	4.295	6	5	9
152	G:G:I25	3.944	5	5	2
153	G:G:R27	8.834	5	5	8
154	G:G:Y40	7.99	4	4	6
155	G:G:D48	6.422	5	13	9
156	G:G:L51	4.354	5	13	6
157	G:G:N59	5.494	5	3	9
158	G:G:P60	6.695	4	3	9
159	G:G:F61	5.67571	7	3	8
160	R:R:F43	6.608	5	19	6
161	R:R:R46	6.965	4	20	6
162	R:R:V105	4.5075	4	8	5
163	R:R:Y109	6.3075	4	0	7
164	R:R:S116	3.645	4	0	8
165	R:R:L117	2.85	4	21	6
166	R:R:N120	7.125	4	2	9
167	R:R:I124	1.865	4	0	7
168	R:R:F127	5.004	5	2	6
169	R:R:Y140	4.98667	6	22	7
170	R:R:H143	7.565	4	0	9
171	R:R:L144	4.6775	4	2	9
172	R:R:F151	5.076	5	2	7
173	R:R:Y161	8.396	5	8	5
174	R:R:Y162	6.08	5	8	5
175	R:R:S166	4.222	5	8	4
176	R:R:W168	10.1233	6	8	9
177	R:R:F170	9.384	5	8	7
178	R:R:F182	6.326	5	2	6
179	R:R:Y183	4.672	5	2	5
180	R:R:Y187	9.042	5	2	8
181	R:R:I190	4.9875	4	2	7
182	R:R:M193	5.092	5	2	8
183	R:R:T194	3.955	4	2	7
184	R:R:R200	6.62667	6	2	9
185	R:R:F201	5.49333	6	23	8
186	R:R:M208	4.128	5	11	4
187	R:R:R214	6.645	4	2	7
188	R:R:Q242	4.525	4	2	4
189	R:R:T243	3.9175	4	8	4
190	R:R:V246	3.158	5	0	3
191	R:R:I251	2.764	5	8	2
192	R:R:T253	4.384	5	8	3
193	R:R:H255	5.3975	4	2	4
194	R:R:D256	5.785	4	8	4
195	R:R:L258	7.09	5	2	5
196	R:R:Y267	6.18167	6	2	4
197	R:R:Y270	8.556	5	0	5
198	R:R:F271	10.394	5	0	5
199	R:R:F274	9.075	4	2	5
200	R:R:F278	5.3875	4	2	6
201	R:R:F279	8.895	6	2	8
202	R:R:S286	3.725	4	2	8
203	R:R:Y290	5.15	6	2	8
204	R:R:L297	4.2875	4	18	8
205	R:R:V318	5.03	4	2	8
206	R:R:F322	3.274	5	2	9
207	R:R:C325	3.94	4	2	8
208	R:R:F326	5.29333	6	2	9
209	R:R:T329	4.045	4	0	6
210	R:R:N330	10.5875	4	0	8
211	R:R:H336	7.766	5	24	4
212	R:R:L340	3.0925	4	24	3
213	R:R:Y350	11.555	4	0	4
214	R:R:F351	8.2825	4	0	1
215	R:R:Y353	8.826	5	0	5
216	R:R:C365	3.378	5	2	8
217	R:R:I370	3.56	4	2	7
218	R:R:Y371	4.74	7	2	9
219	R:R:Y372	5.195	8	2	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D66	B:B:R68	26.9611	3.57	No	No	0	8	5
2	B:B:D66	B:B:L69	26.8163	4.07	No	No	0	8	5
3	A:A:D350	R:R:K135	99.0516	9.68	Yes	No	0	4	7
4	R:R:K134	R:R:K135	99.0873	5.75	No	No	0	5	7
5	R:R:K132	R:R:K134	99.1226	7.18	No	No	0	6	5
6	B:B:F335	R:R:K132	99.157	2.48	Yes	No	0	4	6
7	B:B:D333	B:B:F335	99.2939	5.97	Yes	Yes	0	9	4
8	B:B:D333	B:B:H311	99.235	11.35	Yes	Yes	14	9	9
9	B:B:H311	B:B:T329	98.329	6.85	Yes	Yes	14	9	8
10	B:B:L318	B:B:T329	99.0836	2.95	Yes	Yes	0	6	8
11	B:B:L286	B:B:L318	99.9765	2.77	No	Yes	0	7	6
12	B:B:L286	B:B:V296	100	5.96	No	No	0	7	5
13	B:B:L284	B:B:V296	36.5195	5.96	No	No	0	5	5
14	B:B:L284	B:B:S279	35.4683	6.01	No	No	0	5	9
15	B:B:S279	G:G:D48	31.1178	8.83	No	Yes	13	9	9
16	G:G:D48	G:G:P49	35.505	4.83	Yes	No	0	9	7
17	B:B:M325	G:G:P49	35.6221	6.71	Yes	No	0	5	7
18	B:B:M325	G:G:P60	33.5871	3.35	Yes	Yes	0	5	9
19	B:B:Y85	G:G:P60	25.6118	11.13	Yes	Yes	3	4	9
20	A:A:C214	A:A:H213	16.3813	2.95	Yes	Yes	1	7	8
21	A:A:D350	A:A:N347	17.4135	4.04	Yes	Yes	0	4	8
22	A:A:I343	A:A:N347	17.1134	4.25	No	Yes	0	7	8
23	A:A:I343	R:R:M208	16.6081	2.92	No	Yes	0	7	4
24	A:A:L194	R:R:M208	11.3882	5.65	Yes	Yes	11	4	4
25	A:A:N256	A:A:W258	28.3918	9.04	No	Yes	1	8	5
26	A:A:F259	A:A:N256	28.4012	3.62	Yes	No	1	9	8
27	A:A:F259	A:A:I221	25.6655	7.54	Yes	Yes	1	9	8
28	A:A:I221	A:A:I253	26.3632	2.94	Yes	Yes	0	8	8
29	A:A:F223	A:A:I253	41.7636	5.02	Yes	Yes	0	9	8
30	A:A:C286	A:A:Y230	10.4464	4.03	Yes	Yes	0	6	8
31	A:A:C286	A:A:M243	13.2051	3.24	Yes	No	0	6	8
32	A:A:M243	A:A:V225	13.488	3.04	No	Yes	7	8	7
33	A:A:F223	A:A:V225	32.2501	2.62	Yes	Yes	7	9	7
34	A:A:Q204	A:A:W211	38.9805	12.05	Yes	Yes	1	9	9
35	A:A:W211	B:B:L117	14.9406	3.42	Yes	Yes	1	9	9
36	A:A:C214	B:B:L117	12.7344	3.17	Yes	Yes	1	7	9
37	A:A:Q204	A:A:S206	41.5732	2.89	Yes	No	1	9	8
38	B:B:L69	B:B:Y105	21.3913	7.03	No	Yes	6	5	6
39	B:B:H62	B:B:Y105	12.8405	3.27	No	Yes	0	6	6
40	B:B:H62	B:B:R150	12.7885	12.41	No	No	0	6	6
41	B:B:C148	B:B:L190	10.0876	7.94	No	Yes	0	6	5
42	B:B:S147	B:B:S160	23.4822	4.89	No	Yes	0	9	6
43	B:B:S147	B:B:Y145	23.5934	2.54	No	Yes	0	9	8
44	A:A:S206	B:B:Y145	32.1023	2.54	No	Yes	1	8	8
45	A:A:R208	A:A:W211	30.3942	8	Yes	Yes	1	9	9
46	A:A:L249	A:A:R208	15.1258	3.64	No	Yes	0	9	9
47	A:A:F223	A:A:F250	16.0873	16.08	Yes	Yes	7	9	9
48	A:A:L268	A:A:V225	11.47	4.47	No	Yes	0	8	7
49	A:A:F307	A:A:I303	12.3511	2.51	Yes	Yes	7	8	7
50	A:A:C351	R:R:R200	86.4202	4.18	Yes	Yes	2	4	9
51	A:A:C351	A:A:D350	86.248	4.67	Yes	Yes	2	4	4
52	R:R:R200	R:R:Y371	72.8789	6.17	Yes	Yes	2	9	9
53	R:R:Y371	R:R:Y372	19.1796	2.98	Yes	Yes	2	9	6
54	B:B:F199	B:B:W211	11.7892	18.04	Yes	Yes	9	9	8
55	B:B:C218	B:B:W211	16.1262	7.84	No	Yes	9	5	8
56	B:B:C218	G:G:Q18	17.8175	4.58	No	No	0	5	9
57	G:G:L19	G:G:Q18	16.2329	2.66	No	No	0	9	9
58	G:G:L15	G:G:L19	13.5988	5.54	No	No	0	2	9
59	B:B:A11	G:G:L15	12.8866	3.15	No	No	0	5	2
60	B:B:A11	G:G:V16	12.174	1.7	No	No	0	5	7
61	B:B:L7	G:G:V16	11.461	2.98	Yes	No	0	8	7
62	B:B:T221	G:G:E22	14.6111	2.82	No	Yes	0	7	9
63	B:B:Q220	G:G:E22	19.1778	7.65	Yes	Yes	5	7	9
64	B:B:H142	B:B:S161	12.9243	12.55	Yes	No	1	9	9
65	B:B:S160	B:B:V187	12.3254	8.08	Yes	Yes	0	6	9
66	B:B:H183	B:B:V187	10.1657	6.92	Yes	Yes	9	9	9
67	B:B:D290	B:B:R314	43.3497	13.1	No	Yes	0	6	8
68	B:B:C271	B:B:D290	43.4995	9.34	No	No	0	5	6
69	B:B:C271	B:B:D291	43.6576	6.22	No	No	0	5	8
70	B:B:I273	B:B:Y289	24.798	6.04	No	Yes	0	6	7
71	B:B:G244	B:B:I273	25.0583	7.05	No	No	0	5	6
72	B:B:G244	B:B:S245	24.9229	3.71	No	No	0	5	9
73	B:B:H225	B:B:S245	23.3665	11.16	Yes	No	5	9	9
74	B:B:F222	B:B:Q220	14.8096	5.86	Yes	Yes	5	8	7
75	B:B:F253	B:B:H225	18.2222	3.39	Yes	Yes	5	6	9
76	B:B:F222	B:B:F253	15.4043	11.79	Yes	Yes	5	8	6
77	B:B:G306	B:B:V296	66.3319	1.84	No	No	0	4	5
78	B:B:G306	B:B:V307	66.2686	1.84	No	Yes	0	4	3
79	B:B:N295	B:B:V307	29.4098	2.96	Yes	Yes	4	6	3
80	B:B:D291	B:B:N293	36.9084	12.12	No	No	0	8	5
81	B:B:N293	B:B:V307	36.7903	4.43	No	Yes	4	5	3
82	R:R:R200	R:R:Y290	13.3566	7.2	Yes	Yes	2	9	8
83	R:R:S286	R:R:Y290	11.3316	2.54	Yes	Yes	2	8	8
84	R:R:F322	R:R:S286	14.0164	2.64	Yes	Yes	2	9	8
85	R:R:F322	R:R:I190	22.1537	2.51	Yes	Yes	2	9	7
86	R:R:I190	R:R:Y187	29.2834	3.63	Yes	Yes	2	7	8
87	R:R:F274	R:R:Y187	24.0097	17.54	Yes	Yes	2	5	8
88	R:R:F274	R:R:Y270	22.9842	8.25	Yes	Yes	0	5	5
89	R:R:F271	R:R:Y270	15.7694	13.41	Yes	Yes	0	5	5
90	R:R:M193	R:R:Y371	54.1002	8.38	Yes	Yes	2	8	9
91	R:R:F322	R:R:M193	10.3881	4.98	Yes	Yes	2	9	8
92	R:R:F326	R:R:M193	47.1871	3.73	Yes	Yes	2	9	8
93	R:R:F326	R:R:S360	34.9146	2.64	Yes	No	0	9	8
94	R:R:S360	R:R:T329	34.7416	3.2	No	Yes	0	8	6
95	R:R:T329	R:R:Y353	36.3892	4.99	Yes	Yes	0	6	5
96	R:R:F271	R:R:Y267	11.7684	3.09	Yes	Yes	0	5	4
97	R:R:Y350	R:R:Y353	28.0885	8.94	Yes	Yes	0	4	5
98	R:R:F43	R:R:Y350	19.1317	10.32	Yes	Yes	0	6	4
99	R:R:F43	R:R:L96	16.0463	7.31	Yes	No	0	6	5
100	R:R:L258	R:R:L263	12.4847	6.92	Yes	No	0	5	4
101	R:R:L263	R:R:L44	10.7023	4.15	No	No	0	4	4
102	R:R:L96	R:R:S166	10.4924	6.01	No	Yes	0	5	4
103	R:R:C358	R:R:Y109	10.7472	9.41	No	Yes	0	5	7
104	R:R:N120	R:R:Y372	15.1233	3.49	Yes	Yes	2	9	6
105	R:R:N120	R:R:S116	10.1835	4.47	Yes	Yes	0	9	8
106	R:R:C364	R:R:F151	10.0213	2.79	No	Yes	0	8	7
107	R:R:W168	R:R:Y161	13.6145	9.65	Yes	Yes	8	9	5
108	B:B:R68	B:B:Y85	25.9484	31.9	No	Yes	3	5	4
109	A:A:I253	A:A:R208	15.0079	3.76	Yes	Yes	0	8	9
110	A:A:F223	A:A:L249	14.6737	6.09	Yes	No	0	9	9
111	A:A:H213	B:B:R314	15.1646	3.39	Yes	Yes	1	8	8
112	B:B:N295	B:B:Y289	22.6464	12.79	Yes	Yes	4	6	7
113	B:B:G162	B:B:S161	17.062	3.71	No	No	1	9	9
114	A:A:W258	B:B:R314	25.4207	3	Yes	Yes	1	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8XOS

PDB Summary
PDB	8XOS
Class	A
SubFamily	Peptide
Type	Proteinase-activated
SubType	PAR1
Species	Homo sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3.2
Date	2024-09-18
D.O.I.	doi.org/10.1038/s41422-024-00997-2

Net Summary
I_min	2.48
Number of Linked Nodes	852
Number of Links	1137
Number of Hubs	219
Number of Links mediated by Hubs	772
Number of Communities	24
Number of Nodes involved in Communities	317
Number of Links involved in Communities	492

Path Summary
Number Of Nodes in MetaPath	115
Number Of Links MetaPath	114
Number of Shortest Paths	1109783
Length Of Smallest Path	3
Average Path Length	24.893
Length of Longest Path	53
Minimum Path Strength	1.3
Average Path Strength	6.0624
Maximum Path Strength	24.1
Minimum Path Correlation	0.7
Average Path Correlation	0.980539
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.63158
Average % Of Corr. Nodes	53.0909
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	58.6388
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • dendrite • dendritic tree • neuron projection • non-motile cilium • 9+0 non-motile cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • G-protein beta-subunit binding • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • G-protein alpha-subunit binding • signaling receptor binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • peptide receptor activity • thrombin-activated receptor activity • proteinase-activated receptor activity • G protein-coupled peptide receptor activity • negative regulation of protein transport • protein localization • regulation of systemic arterial blood pressure by renin-angiotensin • regulation of localization • regulation of systemic arterial blood pressure by hormone • establishment of protein localization • nitrogen compound transport • regulation of renal system process • regulation of system process • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • circulatory system process • renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure • cellular macromolecule localization • negative regulation of secretion by cell • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • regulation of systemic arterial blood pressure by circulatory renin-angiotensin • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of endocrine process • renin secretion into blood stream • cellular localization • regulation of systemic arterial blood pressure mediated by a chemical signal • regulation of protein localization • transport • negative regulation of renin secretion into blood stream • protein localization to extracellular region • regulation of secretion by cell • secretion by cell • regulation of renin secretion into blood stream • signal release • negative regulation of cellular process • regulation of multicellular organismal process • renal system process involved in regulation of systemic arterial blood pressure • blood circulation • negative regulation of protein localization • renal system process • regulation of transport • secretion • regulation of blood pressure • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • endocrine process • regulation of systemic arterial blood pressure • protein transport • regulation of cellular localization • macromolecule localization • multicellular organismal-level homeostasis • homeostatic process • homeostasis of number of cells within a tissue • anatomical structure homeostasis • tissue homeostasis • homeostasis of number of cells • regulation of tube diameter • regulation of tube size • positive regulation of biological process • positive regulation of vasoconstriction • regulation of blood circulation • vascular process in circulatory system • regulation of vasoconstriction • positive regulation of multicellular organismal process • blood vessel diameter maintenance • vasoconstriction • regulation of anatomical structure size • thrombin-activated receptor signaling pathway • positive regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • positive regulation of apoptotic process • positive regulation of cellular process • leukocyte homeostasis • immune system process • dendritic cell homeostasis • regulation of body fluid levels • wound healing • cell activation • hemostasis • blood coagulation • coagulation • response to wounding • platelet activation • positive regulation of interleukin-8 production • positive regulation of macromolecule biosynthetic process • positive regulation of metabolic process • positive regulation of biosynthetic process • cytokine production • regulation of cytokine production • positive regulation of macromolecule metabolic process • regulation of biosynthetic process • interleukin-8 production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • positive regulation of gene expression • metabolic process • regulation of macromolecule biosynthetic process • macromolecule metabolic process • positive regulation of cytokine production • regulation of metabolic process • regulation of interleukin-8 production • regulation of calcium ion transport • positive regulation of calcium ion transport • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • monoatomic ion transport • monoatomic cation transport • regulation of metal ion transport • positive regulation of coagulation • regulation of response to external stimulus • positive regulation of blood coagulation • regulation of response to wounding • regulation of coagulation • positive regulation of response to stimulus • regulation of response to stress • positive regulation of hemostasis • regulation of hemostasis • positive regulation of response to wounding • regulation of blood coagulation • response to external stimulus • positive regulation of wound healing • regulation of response to stimulus • regulation of wound healing • vesicle organization • cellular component organization • platelet dense granule organization • organelle organization • secretory granule organization • cellular component organization or biogenesis • endomembrane system organization • regulation of interleukin-1 production • interleukin-1 production • regulation of interleukin-1 beta production • interleukin-1 beta production • collagen biosynthetic process • regulation of collagen biosynthetic process • regulation of collagen metabolic process • positive regulation of collagen metabolic process • positive regulation of collagen biosynthetic process • collagen metabolic process • cell junction organization • neuromuscular junction development • establishment of synaptic specificity at neuromuscular junction • synapse organization • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of canonical NF-kappaB signal transduction • regulation of signal transduction • intracellular signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • regulation of signaling • positive regulation of intracellular signal transduction • canonical NF-kappaB signal transduction • regulation of cell communication • regulation of canonical NF-kappaB signal transduction • positive regulation of signaling • positive regulation of ERK1 and ERK2 cascade • positive regulation of MAPK cascade • regulation of MAPK cascade • MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • interleukin-6 production • positive regulation of interleukin-6 production • regulation of interleukin-6 production • positive regulation of molecular function • regulation of molecular function • positive regulation of hydrolase activity • regulation of catalytic activity • regulation of hydrolase activity • positive regulation of catalytic activity • regulation of GTPase activity • positive regulation of GTPase activity • sensory perception of pain • regulation of nervous system process • regulation of sensory perception • regulation of sensory perception of pain • connective tissue replacement involved in inflammatory response wound healing • wound healing involved in inflammatory response • defense response • inflammatory response to wounding • tissue remodeling • connective tissue replacement • inflammatory response • small GTPase-mediated signal transduction • regulation of small GTPase mediated signal transduction • Rho protein signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • positive regulation of small GTPase mediated signal transduction • trans-synaptic signaling • trans-synaptic signaling, modulating synaptic transmission • modulation of chemical synaptic transmission • trans-synaptic signaling by endocannabinoid • chemical synaptic transmission • synaptic signaling • regulation of trans-synaptic signaling • trans-synaptic signaling by lipid, modulating synaptic transmission • anterograde trans-synaptic signaling • trans-synaptic signaling by lipid • trans-synaptic signaling by endocannabinoid, modulating synaptic transmission • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • anatomical structure morphogenesis • neuron apoptotic process • negative regulation of neuron apoptotic process • negative regulation of programmed cell death • negative regulation of apoptotic process • regulation of neuron apoptotic process • negative regulation of glomerular filtration • regulation of glomerular filtration • renal system process involved in regulation of blood volume • negative regulation of multicellular organismal process • glomerular filtration • renal filtration • positive regulation of cell population proliferation • regulation of cell population proliferation • negative regulation of cell population proliferation • positive regulation of locomotion • regulation of cell motility • positive regulation of cell migration • regulation of locomotion • positive regulation of cell motility • regulation of cell migration • cell migration • cell motility • locomotion • inorganic ion homeostasis • intracellular calcium ion homeostasis • monoatomic ion transmembrane transport • calcium ion homeostasis • negative regulation of sequestering of calcium ion • maintenance of location in cell • monoatomic cation transmembrane transport • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • regulation of sequestering of calcium ion • intracellular monoatomic ion homeostasis • calcium ion transmembrane import into cytosol • sequestering of calcium ion • inorganic ion transmembrane transport • inorganic cation transmembrane transport • maintenance of location • transmembrane transport • release of sequestered calcium ion into cytosol • cellular homeostasis • chemical homeostasis • calcium ion transmembrane transport • cell surface receptor signaling pathway via STAT • positive regulation of receptor signaling pathway via STAT • positive regulation of receptor signaling pathway via JAK-STAT • regulation of receptor signaling pathway via JAK-STAT • cell surface receptor signaling pathway • regulation of receptor signaling pathway via STAT • cell surface receptor signaling pathway via JAK-STAT • regulation of synaptic plasticity • positive regulation of DNA-templated transcription • RNA metabolic process • regulation of primary metabolic process • nucleobase-containing compound metabolic process • RNA biosynthetic process • nucleic acid biosynthetic process • DNA-templated transcription • regulation of RNA metabolic process • regulation of nucleobase-containing compound metabolic process • regulation of RNA biosynthetic process • positive regulation of nucleobase-containing compound metabolic process • primary metabolic process • nucleobase-containing compound biosynthetic process • nucleic acid metabolic process • positive regulation of RNA metabolic process • positive regulation of RNA biosynthetic process • regulation of DNA-templated transcription • positive regulation of smooth muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • smooth muscle contraction • regulation of muscle contraction • regulation of smooth muscle contraction • positive regulation of muscle contraction • cell junction maintenance • cellular component maintenance • cell-cell junction maintenance • cell-cell junction organization • positive regulation of cation transmembrane transport • positive regulation of monoatomic ion transmembrane transport • regulation of release of sequestered calcium ion into cytosol • regulation of transmembrane transport • regulation of monoatomic ion transmembrane transport • regulation of calcium ion transmembrane transport • positive regulation of calcium ion transmembrane transport • positive regulation of transmembrane transport • positive regulation of release of sequestered calcium ion into cytosol • regulation of monoatomic cation transmembrane transport • biological process involved in interspecies interaction between organisms • response to other organism • response to lipopolysaccharide • response to biotic stimulus • response to bacterium • response to external biotic stimulus • response to molecule of bacterial origin • postsynapse • postsynaptic membrane • synaptic membrane • neuromuscular junction • cell surface • membrane microdomain • membrane raft • plasma membrane raft • caveola • early endosome • endosome • intracellular vesicle • cytoplasmic vesicle • platelet dense tubular network • late endosome
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8XOS_Chain_A L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K S T I V K Q M K I T G I V E T H F T F K D L H F K M F D V G A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V N R M H E S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8XOS_Chain_B D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8XOS_Chain_G I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P25116
Sequence	>8XOS_Chain_R S F L L R N P A F I S E D A S G Y L T S S W L T L F V P S V Y T G V F V V S L P L N I M A I V V F I L K M K V K K P A V V Y M L H L A T A D V L F V S V L P F K I S Y Y F S G S D W Q F G S E L C R F V T A A F Y C N M Y A S I L L M T V I S I D R F L A V V Y P M Q S L S W R T L G R A S F T C L A I W A L A I A G V V P L L L K E Q T I Q V P G L N I T T C H D V L N E T L L E G Y Y A Y Y F S A F S A V F F F V P L I I S T V C Y V S I I R C L S S N R S K K S R A L F L S A A V F C I F I I C F G P T N V L L I A H Y S F L S H T S T T E A A Y F A Y L L C V C V S S I S C C I D P L I Y Y Y A S S E C Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XOR	A	Peptide	Proteinase-activated	PAR1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3	2024-09-18	doi.org/10.1038/s41422-024-00997-2
	8XOR (No Gprot)	A	Peptide	Proteinase-activated	PAR1	Homo sapiens	-	-		3	2024-09-18	doi.org/10.1038/s41422-024-00997-2
	8XOS	A	Peptide	Proteinase-activated	PAR1	Homo sapiens	-	-	Gi1/β1/γ2	3.2	2024-09-18	doi.org/10.1038/s41422-024-00997-2
	8XOS (No Gprot)	A	Peptide	Proteinase-activated	PAR1	Homo sapiens	-	-		3.2	2024-09-18	doi.org/10.1038/s41422-024-00997-2
	3VW7	A	Peptide	Proteinase Activated	PAR1	Homo sapiens	-	Vorapaxar; Na	-	2.2	2012-12-12	10.1038/nature11701

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