Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1A:A:I19 3.875419
2A:A:L23 2.79515
3A:A:V34 5.78167635
4A:A:K35 5.0875409
5A:A:L37 6.168519
6A:A:L39 5.5175419
7A:A:K46 3.481676139
8A:A:I49 4.598537
9A:A:Q52 5.20429739
10A:A:M53 5.528539
11A:A:I184 3.362518
12A:A:F189 7.442539
13A:A:F191 10.066535
14A:A:F196 6.15286737
15A:A:K197 10.32417
16A:A:M198 6.1975437
17A:A:F199 6.94667616
18A:A:V201 4.0075419
19A:A:Q204 5.6419
20A:A:S206 4.376518
21A:A:R208 5.186519
22A:A:K210 7.46429719
23A:A:W211 4.4275819
24A:A:I212 3.975419
25A:A:H213 6.09418
26A:A:C214 4.578518
27A:A:F215 5.06444919
28A:A:I221 4.398517
29A:A:F223 4.55333609
30A:A:V225 4.9825447
31A:A:L227 5.2675447
32A:A:Y230 8.34429749
33A:A:D231 11.1449
34A:A:M243 5.718548
35A:A:H244 5.26833644
36A:A:M247 5.5625446
37A:A:F250 5.50667649
38A:A:I253 4.1275418
39A:A:C254 5.27545
40A:A:W258 7.16571715
41A:A:F259 5.03419
42A:A:E261 4.25434
43A:A:I265 3.195439
44A:A:L266 4.035449
45A:A:F267 3.1775839
46A:A:L268 5.416548
47A:A:K270 3.11449
48A:A:F274 6.96448
49A:A:K277 5.14649
50A:A:P282 5.0925445
51A:A:L283 4.3325407
52A:A:C286 5.692546
53A:A:Y287 8.44167648
54A:A:Y290 10.51447
55A:A:Y296 8.842544
56A:A:E298 4.832545
57A:A:Y302 11.9175446
58A:A:I303 3.875408
59A:A:F307 4.57648
60A:A:N311 5.7875447
61A:A:Y320 6.71571738
62A:A:T321 7.875444
63A:A:F323 5.59645
64A:A:T324 5.6975439
65A:A:C325 2.855407
66A:A:N331 5.065638
67A:A:Q333 7.664535
68A:A:F334 9.88434
69A:A:F336 7.97167638
70A:A:I344 5.27436
71A:A:K345 7.615635
72A:A:N346 6.04434
73A:A:L348 3.3175408
74A:A:K349 4.5975434
75A:A:L353 5.2725437
76A:A:Y354 10.405435
77B:B:E10 3.3775478
78B:B:R22 7.0375416
79B:B:I37 3.5402
80B:B:V40 5.3575453
81B:B:M45 3.925614
82B:B:R48 5.68417
83B:B:L51 7.4419
84B:B:H54 7.69143719
85B:B:Y59 7.96618
86B:B:M61 3.78667616
87B:B:W63 5.74817
88B:B:D76 6.414519
89B:B:K78 4.306518
90B:B:I81 4.9775467
91B:B:W82 10.0717619
92B:B:S84 3.965415
93B:B:Y85 8.826514
94B:B:K89 6.24857719
95B:B:H91 4.975465
96B:B:I93 5.02407
97B:B:W99 7.755819
98B:B:Y105 4.468566
99B:B:Y111 6.048514
100B:B:A113 2.045419
101B:B:L117 2.894519
102B:B:C121 3.3975418
103B:B:I123 3.565416
104B:B:Y124 6.494506
105B:B:T128 3.6225403
106B:B:H142 6.02143719
107B:B:Y145 5.8491018
108B:B:L146 4.95417
109B:B:C149 3.16429718
110B:B:F151 4.35875819
111B:B:L152 4.2175413
112B:B:I157 5.6275417
113B:B:T159 5.862519
114B:B:S161 7.2475419
115B:B:G162 4.055419
116B:B:D163 7.454519
117B:B:L168 7.13754156
118B:B:W169 8.445618
119B:B:I171 4.0675416
120B:B:Q176 5.642514
121B:B:H183 6.82286719
122B:B:G185 3.145415
123B:B:D186 7.292519
124B:B:V187 4.395419
125B:B:M188 5.805418
126B:B:L190 6.085415
127B:B:L192 3.295415
128B:B:F199 6.47167619
129B:B:V200 6.2125416
130B:B:S201 5.5725419
131B:B:C204 4.5517
132B:B:D205 6.356519
133B:B:K209 8.10833616
134B:B:L210 4.34405
135B:B:W211 10.2067618
136B:B:D212 7.13754169
137B:B:F222 8.5425418
138B:B:H225 9.24571719
139B:B:D228 6.445419
140B:B:I232 4.71418
141B:B:F234 4.825615
142B:B:F235 6.8025816
143B:B:P236 6.3775417
144B:B:N237 7.492515
145B:B:F241 5.965816
146B:B:T243 4.90833618
147B:B:G244 2.2875415
148B:B:D246 6.145419
149B:B:D247 8.92667619
150B:B:T249 7.3625416
151B:B:C250 3.2525418
152B:B:R251 8.30333618
153B:B:L252 3.2725407
154B:B:F253 7.785416
155B:B:D254 3.8854179
156B:B:R256 5.1575409
157B:B:D258 8.54417
158B:B:Q259 5.448506
159B:B:L261 3.1525405
160B:B:Y264 5.06667615
161B:B:H266 7.938514
162B:B:C271 4.014515
163B:B:T274 3.025418
164B:B:V276 3.3325406
165B:B:F278 5.32143717
166B:B:G282 3.3625419
167B:B:R283 8.15167659
168B:B:L284 4.7225405
169B:B:L285 4.502516
170B:B:Y289 5.84714717
171B:B:D290 9.3675416
172B:B:N295 6.67416
173B:B:W297 4.75667618
174B:B:D298 8.895459
175B:B:R304 5.4475415
176B:B:H311 9.886519
177B:B:R314 14.1475418
178B:B:L318 4.555406
179B:B:T321 6.855417
180B:B:D323 8.1675417
181B:B:G324 2.365409
182B:B:M325 6.5405
183B:B:G330 2.25415
184B:B:S331 6.9875419
185B:B:W332 11.07719
186B:B:D333 9.2525419
187B:B:L336 3.52833617
188B:B:K337 8.728516
189B:B:I338 4.945415
190B:B:W339 8.89833619
191B:B:N340 5.7575419
192G:G:E17 4676
193G:G:R27 5.342518
194G:G:Y40 8.235416
195G:G:D48 5.81667659
196G:G:L51 4.298556
197G:G:V54 4.6425416
198G:G:N59 4.12167619
199G:G:P60 5.9125419
200G:G:F61 5.60778918
201H:H:?402 5.39452020
202H:H:?403 4.87752420
203R:R:R22 3.505405
204R:R:T31 3.7497
205R:R:L45 5.604537
206R:R:L49 5.105439
207R:R:L50 6.3225435
208R:R:V53 4.9975436
209R:R:L57 4.292539
210R:R:I64 5.142535
211R:R:F67 8.74539
212R:R:F70 5.778539
213R:R:C74 5.375437
214R:R:N77 6.0575439
215R:R:I79 7.5925439
216R:R:V80 4.295439
217R:R:M82 4.1925439
218R:R:S84 4.742539
219R:R:P85 2.58409
220R:R:L87 5.47439
221R:R:L92 4.8425438
222R:R:S95 5.9925439
223R:R:L97 3.025428
224R:R:Y99 6.34125839
225R:R:Y103 6.59408
226R:R:F105 9.135429
227R:R:L119 4.04254186
228R:R:I120 4.14406
229R:R:R123 9.35409
230R:R:M126 2.962525
231R:R:C128 4.8925429
232R:R:I129 3.565427
233R:R:P137 4.284539
234R:R:K141 7.795439
235R:R:W143 5.554539
236R:R:R144 6.64333639
237R:R:Y146 9.9875409
238R:R:V148 3.6375439
239R:R:F149 6.838539
240R:R:R152 5.32439
241R:R:V153 2.74438
242R:R:R157 8.87439
243R:R:V158 5.9575439
244R:R:I160 3.97167639
245R:R:L165 4.276539
246R:R:L180 5.4975429
247R:R:W183 5.88875829
248R:R:D187 6.9375429
249R:R:I194 3.89428
250R:R:F215 4.43425
251R:R:S218 4.3175429
252R:R:Y220 7.7925428
253R:R:D222 6.415625
254R:R:W224 6.40143729
255R:R:W229 6.368525
256R:R:K232 5.26529
257R:R:L236 5.5425429
258R:R:Y241 7.162529
259R:R:S251 5.146538
260R:R:P253 4.90125839
261R:R:V254 5.03539
262R:R:I260 3.5525409
263R:R:M261 5.9625427
264R:R:V262 3.91754198
265R:R:V264 4.7675428
266R:R:F275 6.292524
267R:R:R279 9.576526
268R:R:Y280 6.63427
269R:R:F289 6.15714738
270R:R:T292 5.2275428
271R:R:I296 4.0325429
272R:R:F297 5.4225438
273R:R:T300 6.14439
274R:R:N304 5.765439
275R:R:F306 5.4554197
276R:R:I307 6.3775408
277R:R:F308 9.89639
278R:R:Q311 5.205439
279R:R:Q314 6.29439
280R:R:W315 8.036537
281R:R:F318 6.8975439
282R:R:R326 12.855437
283R:R:R327 8.69667935
284R:R:M328 3.164539
285R:R:Y331 4.345409
286S:S:V53 5.4486
287S:S:L57 5.15409
288S:S:I64 4.28525
289S:S:F67 9.196529
290S:S:F70 9.8175429
291S:S:I79 4.01429
292S:S:S84 5.565429
293S:S:P85 2.9875409
294S:S:L87 4.30833629
295S:S:N88 5.9975429
296S:S:L92 4.118528
297S:S:S95 5.7625429
298S:S:Y99 6.35286729
299S:S:Y103 5.7025408
300S:S:F105 10.1875429
301S:S:S115 2.765407
302S:S:M116 3.8925426
303S:S:Q121 6.42429
304S:S:R123 10.7025429
305S:S:M126 3.55505
306S:S:L127 4.115429
307S:S:C128 5.46429
308S:S:I129 2.44167627
309S:S:G130 2.2775429
310S:S:F135 3.584528
311S:S:P137 4.638529
312S:S:K141 7.205429
313S:S:W143 6.72529
314S:S:R144 5.59429
315S:S:Y146 11.765429
316S:S:F149 9.622529
317S:S:I160 5.802529
318S:S:L165 4.032529
319S:S:D176 6.15429
320S:S:L180 5.108529
321S:S:W183 8.085629
322S:S:D187 5.5625409
323S:S:D222 6.726525
324S:S:I225 4.5825427
325S:S:W229 6.498525
326S:S:K232 3.45833629
327S:S:L236 5.426529
328S:S:Y241 6.786529
329S:S:A243 3.545429
330S:S:T246 4.225429
331S:S:V249 8.3775429
332S:S:P253 4.6345109
333S:S:S257 5.2175429
334S:S:I260 3.104529
335S:S:V264 5.865428
336S:S:F275 5.136524
337S:S:V276 2.5125428
338S:S:V277 4.125408
339S:S:R279 9.394526
340S:S:Y280 6.494527
341S:S:F289 4.89714788
342S:S:S293 4.1975489
343S:S:I296 3.3175429
344S:S:T300 5.84529
345S:S:N304 5.44429
346S:S:F306 5.76407
347S:S:F308 9.10667629
348S:S:Q311 6.022529
349S:S:W315 12.7225427
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1B:B:C317 B:B:M61 15.74874.86NoYes076
2B:B:C317 B:B:S316 20.60153.44NoNo079
3B:B:S316 B:B:W332 20.69764.94NoYes099
4A:A:W258 B:B:W332 19.21213.75YesYes159
5A:A:I212 A:A:W258 46.56592.35YesYes195
6A:A:I212 A:A:R208 46.04755.01YesYes199
7A:A:L249 A:A:R208 94.54283.64NoYes189
8A:A:F223 A:A:L249 94.68266.09YesNo098
9A:A:F223 A:A:G40 99.95823.01YesNo099
10A:A:G40 A:A:K46 1001.74NoYes099
11A:A:K46 A:A:L38 76.47022.82YesNo1399
12A:A:I222 A:A:L38 76.61722.85NoNo079
13A:A:I222 A:A:L36 54.20427.14NoNo077
14A:A:L36 A:A:V34 52.56514.47NoYes375
15A:A:V34 R:R:P154 52.73295.3YesNo359
16R:R:P154 R:R:V153 52.81233.53NoYes398
17A:A:G45 A:A:K270 14.30931.74NoYes099
18A:A:G45 A:A:N269 14.40323.39NoNo099
19A:A:C224 A:A:I49 23.61174.91NoYes077
20A:A:C224 A:A:K46 23.58563.23NoYes079
21A:A:F267 A:A:I222 22.57392.51YesNo097
22A:A:F267 A:A:I49 27.64772.51YesYes397
23A:A:S206 A:A:W211 12.78674.94YesYes189
24B:B:G162 B:B:Y145 13.26255.79YesYes198
25A:A:K210 B:B:Y145 14.45813.58YesYes198
26A:A:K210 B:B:D246 13.35975.53YesYes199
27A:A:F267 A:A:F334 54.88042.14YesYes394
28A:A:F334 A:A:Y320 59.77032.06YesYes348
29A:A:K345 A:A:Y320 48.8822.39YesYes358
30A:A:I344 R:R:M328 11.18882.92YesYes369
31A:A:I344 R:R:F149 12.5336.28YesYes369
32A:A:K345 A:A:Y354 38.504415.53YesYes355
33R:R:Q151 R:R:V153 52.83752.87NoYes398
34R:R:Q151 R:R:V158 52.9185.73NoYes399
35A:A:L348 A:A:Y354 38.88894.69YesYes085
36A:A:L348 A:A:L353 39.10342.77YesYes087
37R:R:I160 R:R:V158 53.73513.07YesYes399
38A:A:L353 R:R:S84 38.35583YesYes379
39B:B:F151 B:B:Y111 12.22822.06YesYes194
40B:B:C149 B:B:L146 12.59753.17YesYes187
41B:B:L146 B:B:S161 16.9034.5YesYes179
42B:B:G162 B:B:S161 25.12421.86YesYes199
43B:B:D246 B:B:S227 13.39882.94YesNo196
44B:B:D290 B:B:R314 14.220825.01YesYes168
45B:B:C271 B:B:D290 14.23466.22YesYes156
46B:B:C271 B:B:Y289 13.59034.03YesYes157
47B:B:W297 B:B:Y289 11.58035.79YesYes187
48B:B:W297 B:B:Y264 11.03679.65YesYes185
49R:R:I160 R:R:W143 25.35745.87YesYes399
50R:R:L242 R:R:W143 25.77013.42NoYes099
51R:R:L242 R:R:Y238 25.725111.72NoNo098
52R:R:Y238 R:R:Y241 25.68392.98NoYes089
53R:R:Y241 S:S:M261 49.395314.37YesNo297
54S:S:M261 S:S:N265 49.91182.8NoNo077
55S:S:N265 S:S:V264 49.842.96NoYes078
56S:S:F135 S:S:V264 23.87942.62YesYes288
57S:S:F135 S:S:L267 23.74583.65YesNo287
58H:H:?402 S:S:L267 47.18825.16YesNo207
59R:R:I160 R:R:K147 28.0232.91YesNo398
60R:R:K147 R:R:Y146 28.01062.39NoYes089
61R:R:L245 R:R:Y146 40.285617.58NoYes099
62R:R:L245 R:R:Y241 36.163612.89NoYes299
63S:S:L236 S:S:V264 25.239410.43YesYes298
64S:S:L236 S:S:L267 23.60246.92YesNo297
65H:H:?402 S:S:L127 29.13435.16YesYes209
66H:H:?402 S:S:T300 12.94862.75YesYes209
67R:R:P85 R:R:S84 18.63421.78YesYes099
68R:R:P85 R:R:T71 18.25781.75YesNo099
69R:R:F308 R:R:T71 18.1053.89YesNo099
70R:R:F308 R:R:L92 36.78318.53YesYes398
71R:R:L92 R:R:N304 26.62574.12YesYes389
72R:R:N304 R:R:T300 26.59472.92YesYes399
73R:R:T300 R:R:T98 29.08824.71YesNo099
74H:H:?403 R:R:T98 27.12942.06YesNo009
75R:R:K141 R:R:S84 19.69987.65YesYes399
76R:R:K141 R:R:N88 18.15886.99YesNo399
77R:R:F308 R:R:N88 17.9247.25YesNo399
78H:H:?403 R:R:R279 10.88877.36YesYes206
79S:S:F105 S:S:L127 25.56172.44YesYes299
80S:S:F105 S:S:R123 25.488326.72YesYes299
81S:S:I120 S:S:R123 24.369810.02NoYes269
82S:S:I120 S:S:M116 23.16622.92NoYes266
83S:S:H214 S:S:M116 22.21451.31NoYes056
84S:S:H214 S:S:Q193 21.97589.89NoNo057
85R:R:V201 S:S:Q193 21.4982.87NoNo077
86R:R:V201 R:R:V206 21.25918.02NoNo075
87R:R:V206 S:S:I32 21.02013.07NoNo055
88R:R:M199 S:S:I32 20.54195.83NoNo075
89R:R:C208 R:R:M199 10.15144.86NoNo067
90R:R:V197 S:S:C28 19.339410.25NoNo089
91R:R:M199 S:S:T31 10.15143.01NoNo077
92R:R:S210 R:R:V197 13.06453.23NoNo078
93R:R:S210 S:S:L24 12.58143NoNo077
94R:R:T31 S:S:L24 10.1651.47YesNo077
95R:R:I64 R:R:L92 10.99544.28YesYes358
96R:R:F149 R:R:V249 13.33339.18YesNo399
97R:R:T246 R:R:V249 13.45763.17NoNo099
98R:R:Y241 S:S:A243 12.60332.67YesYes299
99S:S:A243 S:S:I260 10.42824.87YesYes299
100A:A:R208 A:A:W211 48.68467YesYes199
101A:A:W211 B:B:Y145 35.93111.93YesYes198
102B:B:M61 B:B:W63 10.88335.82YesYes167
103A:A:S206 B:B:G162 11.97291.86YesYes189
104A:A:W258 B:B:R314 27.28196YesYes158
105B:B:R314 B:B:T274 14.26432.59YesYes188
106B:B:S275 B:B:T274 12.61254.8NoYes188
107B:B:L318 B:B:S275 12.51757.51YesNo068
108R:R:T246 R:R:Y146 12.41493.75NoYes099
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 8YK0
Class C
SubFamily Orphan
Type Orphan
SubType GPR156
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners Gi3/Beta1/Gamma2
PDB Resolution 2.4
Date 2025-02-05
D.O.I. doi.org/10.1038/s41467-024-54681-5
Net Summary
Imin 1.74
Number of Linked Nodes 1180
Number of Links 1694
Number of Hubs 349
Number of Links mediated by Hubs 1220
Number of Communities 19
Number of Nodes involved in Communities 549
Number of Links involved in Communities 909
Path Summary
Number Of Nodes in MetaPath 109
Number Of Links MetaPath 108
Number of Shortest Paths 5468165
Length Of Smallest Path 3
Average Path Length 29.9382
Length of Longest Path 69
Minimum Path Strength 1.34
Average Path Strength 5.20232
Maximum Path Strength 24.51
Minimum Path Correlation 0.7
Average Path Correlation 0.997897
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.57143
Average % Of Corr. Nodes 52.3879
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 62.4995
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeMW9
PDB ResiduesH:H:?402 H:H:?403
Environment DetailsOpen EMBL-EBI Page
CodeMW9
Name(21R,24R,27S)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9Z)-octadec-9-enoate
Synonyms1-stearoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
Identifier
FormulaC42 H81 O10 P
Molecular Weight777.06
SMILES
PubChem24779551
Formal Charge0
Total Atoms134
Total Chiral Atoms2
Total Bonds133
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainA
ProteinG Protein α Sub unit
UniProtP08754
Sequence
>8YK0_Chain_A
SAEDKAAVE RSKMIDRNL REDGEKAAK EVKLLLLGA GESGKTIVK 
QMKIIGIVE THFTFKDLY FKMFDVGQR SERKKWIHC FEGVTAIIF 
CVALSDYDL VLAEEEMNR MHSMKLFDS ICNNKWFTE TSIILFLNK 
KDLFEEKIK RSPLTICYP EYTGSNTYE EAAAYIQCQ FEDLNRRKD 
TKEIYTHFT CTDTKNVQF VFDAVTDVI IKNNLKECG LYNAAS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>8YK0_Chain_B
ELDQLRQEA EQLKNQIRD ARKACADAT LSQITNNID PVGRIQMRT 
RRTLRGHLA KIYAMHWGT DSRLLVSAS QDGKLIIWD SYTTNKVHA 
IPLRSSWVM TCAYAPSGN YVACGGLDN ICSIYNLKT REGNVRVSR 
ELAGHTGYL SCCRFLDDN QIVTSSGDT TCALWDIET GQQTTTFTG 
HTGDVMSLS LAPDTRLFV SGACDASAK LWDVREGMC RQTFTGHES 
DINAICFFP NGNAFATGS DDATCRLFD LRADQELMT YSHDNIICG 
ITSVSFSKS GRLLLAGYD DFNCNVWDA LKADRAGVL AGHDNRVSC 
LGVTDDGMA VATGSWDSF LKIWN


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>8YK0_Chain_G
ASIAQARKL VEQLKMEAN IDRIKVSKA AADLMAYCE AHAKEDPLL 
TPVPASENP FRE


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtQ8NFN8
Sequence
>8YK0_Chain_R
RPLHDLCKT TITSSHHSS KTISSLSPV LLGIVWTFL SCGLLLILF 
FLAFTIHCR KNRIVKMSS PNLNIVTLL GSCLTYSSA YLFGIQDVL 
VGSSMETLI QTRLSMLCI GTSLVFGPI LGKSWRLYK VFTQRVPDK 
RVIIKDLQL LGLVAALLM ADVILLMTW VLTDPIQCL QILSVSMTV 
TGKDVSCTS TSTHFCASR YSDVWIALI WGCKGLLLL YGAYLAGLT 
GHVSSPPVN QSLTIMVGV NLLVLAAGL LFVVTRYLH SWPNLVFGL 
TSGGIFVCT TTINCFIFI PQLKQWKAF EEENQTIRR MAKYFSTPN 
KS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainS
ProteinReceptor
UniProtQ8NFN8
Sequence
>8YK0_Chain_S
RPLHDLCKT TITSSHHSS KTISSLSPV LLGIVWTFL SCGLLLILF 
FLAFTIHCR KNRIVKMSS PNLNIVTLL GSCLTYSSA YLFGIQDVL 
VGSSMETLI QTRLSMLCI GTSLVFGPI LGKSWRLYK VFTQRVPDK 
RVIIKDLQL LGLVAALLM ADVILLMTW VLTDPIQCL QILSVSMTV 
TGKDVSCTS TSTHFCASR YSDVWIALI WGCKGLLLL YGAYLAGLT 
GHVSSPPVN QSLTIMVGV NLLVLAAGL LFVVTRYLH SWPNLVFGL 
TSGGIFVCT TTINCFIFI PQLKQWKAF E


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8YJPCOrphanOrphanGPR156Homo sapiens---3.092025-02-05doi.org/10.1038/s41467-024-54681-5
8YK0COrphanOrphanGPR156Homo sapiens--Gi3/β1/γ22.42025-02-05doi.org/10.1038/s41467-024-54681-5
8YK0 (No Gprot) COrphanOrphanGPR156Homo sapiens--2.42025-02-05doi.org/10.1038/s41467-024-54681-5
8IEBCOrphanOrphanGPR156Homo sapiensA1LYA--3.032024-02-14doi.org/10.1038/s41594-024-01224-7
8IEDCOrphanOrphanGPR156Homo sapiensA1LYA-Go/β1/γ23.332024-02-14doi.org/10.1038/s41594-024-01224-7
8IED (No Gprot) COrphanOrphanGPR156Homo sapiensA1LYA-3.332024-02-14doi.org/10.1038/s41594-024-01224-7
8IEICOrphanOrphanGPR156Homo sapiensA1LYA--2.622024-02-14doi.org/10.1038/s41594-024-01224-7
8IEPCOrphanOrphanGPR156Homo sapiensA1LYA--2.612024-02-14doi.org/10.1038/s41594-024-01224-7




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