psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F48	R:R:L44	3.65	No	No	0	4	5
2	R:R:P46	R:R:V45	3.53	No	Yes	0	6	5
3	R:R:F49	R:R:V45	5.24	Yes	Yes	1	7	5
4	R:R:L102	R:R:V45	5.96	No	Yes	1	5	5
5	R:R:F49	R:R:F98	4.29	Yes	Yes	1	7	6
6	R:R:F49	R:R:L102	4.87	Yes	No	1	7	5
7	R:R:F49	R:R:Y313	9.28	Yes	Yes	1	7	7
8	R:R:L92	R:R:M53	5.65	No	No	0	7	7
9	R:R:L57	R:R:S61	4.5	No	No	0	6	4
10	R:R:G59	R:R:P320	4.06	No	No	0	8	9
11	R:R:A85	R:R:N60	4.69	No	No	0	9	9
12	R:R:D88	R:R:N60	12.12	No	No	0	9	9
13	R:R:N60	R:R:P320	6.52	No	No	0	9	9
14	R:R:F334	R:R:L62	8.53	No	No	0	6	6
15	R:R:A85	R:R:V63	3.39	No	No	0	9	9
16	R:R:F330	R:R:V63	6.55	Yes	No	0	8	9
17	R:R:H70	R:R:Y65	30.49	No	No	0	5	4
18	R:R:F330	R:R:V66	5.24	Yes	No	0	8	7
19	R:R:F334	R:R:V66	5.24	No	No	0	6	7
20	R:R:V337	R:R:V66	4.81	No	No	0	6	7
21	R:R:I67	R:R:N78	5.66	Yes	No	0	7	8
22	R:R:A82	R:R:I67	4.87	No	Yes	0	6	7
23	R:R:F330	R:R:I67	3.77	Yes	Yes	0	8	7
24	R:R:H70	R:R:R69	14.67	No	No	0	5	5
25	R:R:H70	R:R:V337	5.54	No	No	0	5	6
26	R:R:K71	R:R:P72	11.71	No	No	0	6	5
27	R:R:K71	R:R:M73	8.64	No	No	0	6	7
28	R:R:M73	R:R:N78	9.82	No	No	0	7	8
29	R:R:N78	R:R:T75	5.85	No	No	0	8	7
30	R:R:R154	R:R:V76	14.38	Yes	No	0	7	6
31	R:R:P156	R:R:V76	3.53	No	No	0	1	6
32	R:R:R154	R:R:T77	6.47	Yes	No	0	7	8
33	R:R:A159	R:R:F79	5.55	No	No	0	7	6
34	R:R:F79	R:R:L160	4.87	No	No	0	6	3
35	R:R:D139	R:R:Y80	10.34	No	No	0	8	7
36	R:R:A159	R:R:Y80	4	No	No	0	7	7
37	R:R:V162	R:R:Y80	5.05	No	No	0	5	7
38	R:R:N83	R:R:T87	4.39	No	Yes	0	9	8
39	R:R:N83	R:R:S163	10.43	No	No	0	9	8
40	R:R:L84	R:R:T132	4.42	No	No	0	9	8
41	R:R:L84	R:R:M136	5.65	No	No	0	9	9
42	R:R:T132	R:R:T87	9.42	No	Yes	0	8	8
43	R:R:T87	R:R:W167	4.85	Yes	No	0	8	9
44	R:R:D88	R:R:S316	8.83	No	No	0	9	9
45	R:R:T90	R:R:W167	8.49	No	No	0	6	9
46	R:R:F91	R:R:S125	6.61	Yes	No	1	7	8
47	R:R:F91	R:R:W276	5.01	Yes	Yes	1	7	8
48	R:R:F91	R:R:S312	3.96	Yes	No	1	7	7
49	R:R:F91	R:R:Y313	4.13	Yes	Yes	1	7	7
50	R:R:F91	R:R:S316	6.61	Yes	No	0	7	9
51	R:R:L92	R:R:S316	6.01	No	No	0	7	9
52	R:R:C94	R:R:I121	6.55	No	No	0	4	5
53	R:R:C94	R:R:Q122	7.63	No	No	1	4	6
54	R:R:C94	R:R:S125	5.16	No	No	1	4	8
55	R:R:C95	R:R:Y313	14.79	No	Yes	0	7	7
56	R:R:P97	R:R:V96	3.53	No	No	0	9	8
57	R:R:P97	R:R:V118	5.3	No	No	0	9	5
58	R:R:F98	R:R:L101	8.53	Yes	No	0	6	4
59	R:R:F98	R:R:L102	9.74	Yes	No	1	6	5
60	R:R:F98	R:R:H309	21.5	Yes	No	1	6	6
61	R:R:F98	R:R:Y313	4.13	Yes	Yes	1	6	7
62	L:L:L218	R:R:F98	4.87	No	Yes	0	0	6
63	L:L:N214	R:R:L101	6.87	No	No	0	0	4
64	L:L:G217	R:R:L101	3.42	No	No	0	0	4
65	R:R:P104	R:R:Y103	9.74	No	No	0	5	5
66	L:L:N214	R:R:G107	5.09	No	No	0	0	5
67	R:R:L110	R:R:W108	12.53	No	No	0	7	8
68	R:R:C115	R:R:W108	3.92	No	No	0	9	8
69	R:R:L110	R:R:M114	5.65	No	No	0	7	6
70	R:R:D112	R:R:K116	8.3	No	No	0	3	7
71	R:R:D112	R:R:L183	4.07	No	No	0	3	3
72	R:R:C115	R:R:C191	7.28	No	No	0	9	9
73	L:L:L218	R:R:V118	7.45	No	No	0	0	5
74	R:R:H181	R:R:N119	28.06	Yes	No	0	5	5
75	L:L:L218	R:R:N119	6.87	No	No	0	0	5
76	R:R:V124	R:R:Y120	8.83	No	Yes	2	5	6
77	R:R:S174	R:R:Y120	3.82	No	Yes	2	7	6
78	R:R:L178	R:R:Y120	9.38	No	Yes	0	5	6
79	R:R:Q122	R:R:S125	4.33	No	No	1	6	8
80	R:R:Q123	R:R:S174	5.78	Yes	No	2	4	7
81	R:R:Q123	R:R:V177	5.73	Yes	No	0	4	5
82	R:R:F204	R:R:Q123	3.51	Yes	Yes	2	5	4
83	R:R:N208	R:R:Q123	3.96	Yes	Yes	2	5	4
84	L:L:R219	R:R:Q123	7.01	Yes	Yes	2	0	4
85	R:R:S170	R:R:V124	4.85	No	No	0	7	5
86	R:R:S174	R:R:V124	6.46	No	No	2	7	5
87	R:R:L212	R:R:V126	4.47	Yes	No	0	6	7
88	R:R:V126	R:R:W276	8.58	No	Yes	0	7	8
89	L:L:F220	R:R:V126	13.11	Yes	No	0	0	7
90	R:R:Q127	R:R:W131	12.05	Yes	No	0	6	6
91	R:R:Q127	R:R:V173	5.73	Yes	No	4	6	5
92	R:R:Q127	R:R:Y207	5.64	Yes	No	4	6	4
93	R:R:L212	R:R:Q127	9.32	Yes	Yes	0	6	6
94	R:R:A128	R:R:W167	7.78	No	No	0	7	9
95	R:R:I166	R:R:W131	3.52	No	No	0	7	6
96	R:R:F272	R:R:L133	3.65	Yes	No	0	9	8
97	R:R:L133	R:R:Y323	4.69	No	Yes	0	8	9
98	R:R:P216	R:R:T134	3.5	No	No	0	9	7
99	R:R:M136	R:R:Y323	5.99	No	Yes	0	9	9
100	R:R:S137	R:R:T220	9.59	No	No	6	9	8
101	R:R:S137	R:R:Y224	11.45	No	Yes	6	9	9
102	R:R:D139	R:R:V143	4.38	No	No	3	8	8
103	R:R:D139	R:R:R154	14.29	No	Yes	3	8	7
104	R:R:R140	R:R:Y224	10.29	No	Yes	0	9	9
105	R:R:R140	R:R:Y323	8.23	No	Yes	0	9	9
106	R:R:V145	R:R:W141	7.36	No	No	0	7	8
107	R:R:F146	R:R:Y142	8.25	No	Yes	0	6	4
108	R:R:R149	R:R:Y142	5.14	No	Yes	3	5	4
109	R:R:R153	R:R:Y142	8.23	Yes	Yes	3	4	4
110	R:R:R154	R:R:V143	6.54	Yes	No	3	7	8
111	R:R:M227	R:R:T144	9.03	No	No	0	9	8
112	R:R:F146	R:R:V145	10.49	No	No	0	6	7
113	R:R:H230	R:R:V145	8.3	No	No	0	5	7
114	R:R:R149	R:R:R153	9.6	No	Yes	3	5	4
115	R:R:P156	R:R:T155	3.5	No	No	0	1	7
116	R:R:R157	R:R:T155	5.17	No	No	0	4	7
117	R:R:L160	R:R:L164	4.15	No	No	0	3	4
118	R:R:V173	R:R:Y207	3.79	No	No	4	5	4
119	R:R:H181	R:R:L180	11.57	Yes	No	0	5	4
120	R:R:F195	R:R:L180	13.4	Yes	No	2	6	4
121	R:R:F204	R:R:L180	7.31	Yes	No	2	5	4
122	R:R:E193	R:R:H181	11.08	No	Yes	0	4	5
123	L:L:R219	R:R:H181	3.39	Yes	Yes	0	0	5
124	R:R:A194	R:R:R182	8.3	No	No	0	3	5
125	R:R:A189	R:R:L183	4.73	No	No	0	4	3
126	R:R:S184	R:R:Y190	5.09	No	No	0	3	4
127	R:R:G186	R:R:P187	4.06	No	No	0	1	1
128	R:R:E193	R:R:F195	4.66	No	Yes	0	4	6
129	R:R:E193	R:R:Q286	3.82	No	No	0	4	4
130	R:R:F195	R:R:P196	4.33	Yes	No	0	6	4
131	R:R:E201	R:R:F195	19.82	No	Yes	0	4	6
132	R:R:F195	R:R:F204	6.43	Yes	Yes	2	6	5
133	R:R:L200	R:R:P196	4.93	No	No	0	3	4
134	R:R:A199	R:R:R202	4.15	No	No	0	1	1
135	L:L:R219	R:R:F204	7.48	Yes	Yes	2	0	5
136	R:R:L206	R:R:L210	4.15	No	No	0	5	5
137	R:R:A211	R:R:Y207	5.34	No	No	0	4	4
138	R:R:L212	R:R:N208	8.24	Yes	Yes	0	6	5
139	R:R:L283	R:R:N208	4.12	No	Yes	2	5	5
140	L:L:F220	R:R:N208	7.25	Yes	Yes	2	0	5
141	R:R:L209	R:R:Y213	3.52	No	Yes	7	5	8
142	R:R:L209	R:R:Q280	6.65	No	No	7	5	7
143	R:R:L210	R:R:L214	4.15	No	No	0	5	4
144	R:R:L210	R:R:L215	4.15	No	No	0	5	6
145	R:R:L214	R:R:Y213	3.52	No	Yes	0	4	8
146	R:R:G277	R:R:Y213	4.35	No	Yes	0	6	8
147	R:R:Q280	R:R:Y213	9.02	No	Yes	7	7	8
148	R:R:F272	R:R:L217	3.65	Yes	No	0	9	6
149	R:R:T220	R:R:Y224	4.99	No	Yes	6	8	9
150	R:R:C221	R:R:V269	3.42	No	No	0	5	8
151	R:R:M227	R:R:Y224	3.59	No	Yes	0	9	9
152	R:R:V265	R:R:Y224	20.19	No	Yes	0	8	9
153	R:R:L228	R:R:S262	4.5	No	No	0	5	7
154	R:R:L228	R:R:V265	4.47	No	No	0	5	8
155	R:R:H230	R:R:V234	4.15	No	No	0	5	6
156	R:R:L231	R:R:V261	4.47	No	No	0	8	8
157	R:R:Q246	R:R:S243	4.33	No	No	0	4	4
158	R:R:L245	R:R:Q248	6.65	No	No	0	3	4
159	R:R:L322	R:R:V268	5.96	Yes	No	5	8	8
160	R:R:V268	R:R:Y323	7.57	No	Yes	5	8	9
161	R:R:L271	R:R:L318	5.54	No	No	0	7	6
162	R:R:F272	R:R:W276	8.02	Yes	Yes	0	9	8
163	R:R:C275	R:R:N315	7.87	No	No	0	9	9
164	R:R:S312	R:R:W276	8.65	No	Yes	1	7	8
165	R:R:N315	R:R:W276	13.56	No	Yes	0	9	8
166	R:R:G277	R:R:P278	4.06	No	No	0	6	9
167	R:R:P278	R:R:W307	8.11	No	No	0	9	5
168	L:L:F220	R:R:I279	5.02	Yes	No	0	0	7
169	R:R:L281	R:R:L285	6.92	No	No	0	6	6
170	R:R:F282	R:R:Q286	3.51	No	No	0	5	4
171	R:R:F282	R:R:L304	4.87	No	No	0	5	6
172	R:R:F282	R:R:K305	18.61	No	No	0	5	4
173	L:L:R219	R:R:L283	7.29	Yes	No	2	0	5
174	L:L:F220	R:R:L283	3.65	Yes	No	2	0	5
175	R:R:L285	R:R:W294	9.11	No	No	0	6	1
176	R:R:G289	R:R:P290	4.06	No	No	0	3	1
177	R:R:P290	R:R:P296	7.79	No	No	0	1	3
178	R:R:P296	R:R:W294	4.05	No	No	0	3	1
179	R:R:H295	R:R:P296	7.63	No	No	0	3	3
180	R:R:H295	R:R:R297	5.64	No	No	0	3	2
181	R:R:H295	R:R:S298	4.18	No	No	0	3	4
182	L:L:W213	R:R:R297	12	No	No	0	0	2
183	L:L:F216	R:R:R297	9.62	No	No	0	0	2
184	R:R:Y299	R:R:Y302	5.96	No	Yes	8	4	5
185	L:L:Y211	R:R:Y299	13.9	No	No	8	0	4
186	R:R:T306	R:R:Y302	6.24	No	Yes	0	4	5
187	L:L:Y211	R:R:Y302	11.91	No	Yes	8	0	5
188	L:L:S215	R:R:Y302	6.36	No	Yes	0	0	5
189	L:L:F216	R:R:Y302	5.16	No	Yes	0	0	5
190	R:R:H309	R:R:K305	11.79	No	No	0	6	4
191	R:R:M311	R:R:W307	5.82	No	No	0	7	5
192	R:R:H309	R:R:Y313	11.98	No	Yes	1	6	7
193	R:R:L318	R:R:S314	4.5	No	No	0	6	5
194	R:R:N315	R:R:N319	10.9	No	No	0	9	9
195	R:R:N319	R:R:Y323	3.49	No	Yes	0	9	9
196	R:R:L321	R:R:L326	4.15	No	No	0	7	7
197	R:R:L322	R:R:Y323	8.21	Yes	Yes	5	8	9
198	R:R:A324	R:R:F330	9.71	No	Yes	0	7	8
199	R:R:F325	R:R:F330	5.36	No	Yes	0	6	8
200	R:R:H329	R:R:Q332	3.71	No	No	0	6	5
201	L:L:N212	L:L:N214	5.45	No	No	0	0	0
202	L:L:N212	L:L:S215	8.94	No	No	0	0	0
203	L:L:F220	L:L:R219	5.34	Yes	Yes	2	0	0
204	R:R:A219	R:R:T134	3.36	No	No	0	6	7
205	R:R:C68	R:R:I64	3.27	No	No	0	4	7
206	R:R:S184	R:R:S192	3.26	No	No	0	3	4
207	R:R:A308	R:R:I279	3.25	No	No	0	6	7
208	R:R:A333	R:R:M73	3.22	No	No	0	6	7
209	R:R:R335	R:R:R336	3.2	No	No	0	4	5
210	R:R:C130	R:R:L212	3.17	No	Yes	0	7	6
211	R:R:T220	R:R:V269	3.17	No	No	0	8	8
212	R:R:C275	R:R:L271	3.17	No	No	0	9	7
213	R:R:C115	R:R:N119	3.15	No	No	0	9	5
214	R:R:A317	R:R:L318	3.15	No	No	0	7	6
215	R:R:T129	R:R:T87	3.14	No	Yes	0	9	8
216	R:R:R154	R:R:Y142	3.09	Yes	Yes	3	7	4
217	R:R:F272	R:R:Y213	3.09	Yes	Yes	0	9	8
218	R:R:A256	R:R:E252	3.02	No	No	0	5	3
219	R:R:L200	R:R:S197	3	No	No	0	3	3
220	R:R:L44	R:R:V45	2.98	No	Yes	0	5	5
221	R:R:L62	R:R:V58	2.98	No	No	0	6	4
222	R:R:L93	R:R:V89	2.98	No	No	0	5	7
223	R:R:L110	R:R:V109	2.98	No	No	0	7	3
224	R:R:L228	R:R:V261	2.98	No	No	0	5	8
225	R:R:L288	R:R:V284	2.98	No	No	0	4	5
226	R:R:I67	R:R:I81	2.94	Yes	No	0	7	8
227	L:L:W213	R:R:Y190	2.89	No	No	0	0	4
228	R:R:F272	R:R:P216	2.89	Yes	No	0	9	9
229	R:R:G111	R:R:W108	2.81	No	No	0	8	8
230	R:R:C310	R:R:F49	2.79	No	Yes	0	5	7
231	R:R:P46	R:R:Y103	2.78	No	No	0	6	5
232	R:R:A150	R:R:R154	2.77	No	Yes	0	6	7
233	R:R:L322	R:R:L326	2.77	Yes	No	0	8	7
234	R:R:A273	R:R:Y213	2.67	No	Yes	0	5	8
235	R:R:F79	R:R:S163	2.64	No	No	0	6	8
236	R:R:R331	R:R:S328	2.64	No	No	0	8	5
237	R:R:R253	R:R:V257	2.62	No	No	0	3	6
238	R:R:A226	R:R:W141	2.59	No	No	0	5	8
239	R:R:A301	R:R:W294	2.59	No	No	0	6	1
240	R:R:F117	R:R:M114	2.49	No	No	0	5	6
241	R:R:L158	R:R:R153	2.43	No	Yes	0	4	4
242	R:R:L52	R:R:Y313	2.34	No	Yes	0	7	7
243	R:R:L105	R:R:Y103	2.34	No	No	0	4	5
244	R:R:Q332	R:R:R336	2.34	No	No	0	5	5
245	R:R:G186	R:R:P185	2.03	No	No	0	1	2
246	R:R:A172	R:R:G169	1.95	No	No	0	4	4
247	R:R:A254	R:R:G255	1.95	No	No	0	3	3
248	R:R:A175	R:R:P176	1.87	No	No	0	5	6
249	R:R:G169	R:R:V168	1.84	No	No	0	4	5
250	R:R:A205	R:R:A287	1.79	No	No	0	5	5
251	R:R:P185	R:R:S184	1.78	No	No	0	2	3
252	R:R:C223	R:R:S137	1.72	No	No	0	7	9
253	R:R:G56	R:R:L55	1.71	No	No	0	8	6
254	R:R:G56	R:R:L92	1.71	No	No	0	8	7
255	R:R:C223	R:R:V138	1.71	No	No	0	7	7
256	R:R:A199	R:R:S197	1.71	No	No	0	1	3
257	R:R:G247	R:R:L250	1.71	No	No	0	4	3
258	R:R:A300	R:R:S298	1.71	No	No	0	3	4
259	R:R:A135	R:R:V162	1.7	No	No	0	7	5
260	R:R:C95	R:R:T99	1.69	No	No	0	7	6
261	R:R:A100	R:R:T99	1.68	No	No	0	7	6
262	R:R:L105	R:R:P106	1.64	No	No	0	4	5
263	R:R:L183	R:R:P185	1.64	No	No	0	3	2
264	R:R:A82	R:R:I64	1.62	No	No	0	6	7
265	R:R:V257	R:R:V261	1.6	No	No	0	6	8
266	R:R:T90	R:R:V89	1.59	No	No	0	6	7
267	R:R:A42	R:R:L44	1.58	No	No	0	4	5
268	R:R:A244	R:R:L245	1.58	No	No	0	4	3
269	R:R:A254	R:R:L250	1.58	No	No	0	3	3
270	R:R:A267	R:R:L322	1.58	No	Yes	0	6	8
271	R:R:A287	R:R:L288	1.58	No	No	0	5	4
272	R:R:A333	R:R:Q332	1.52	No	No	0	6	5
273	R:R:A287	R:R:E201	1.51	No	No	0	5	4
274	R:R:G107	R:R:R188	1.5	No	No	0	5	2
275	R:R:G232	R:R:R258	1.5	No	No	0	5	7
276	R:R:G255	R:R:R258	1.5	No	No	0	3	7
277	R:R:G327	R:R:R331	1.5	No	No	0	8	8
278	R:R:L57	R:R:V89	1.49	No	No	0	6	7
279	R:R:F146	R:R:P147	1.44	No	No	0	6	8
280	R:R:Q248	R:R:V249	1.43	No	No	0	4	2
281	R:R:L148	R:R:L151	1.38	No	No	0	6	4
282	R:R:P46	R:R:W43	1.35	No	No	0	6	2
283	R:R:A171	R:R:Y120	1.33	No	Yes	0	4	6
284	R:R:R263	R:R:S262	1.32	No	No	0	7	7
285	R:R:H152	R:R:L151	1.29	No	No	0	5	4
286	R:R:D112	R:R:R182	1.19	No	No	0	3	5
287	R:R:E201	R:R:R198	1.16	No	No	0	4	1
288	R:R:L47	R:R:W43	1.14	No	No	0	6	2
289	R:R:H152	R:R:R153	1.13	No	Yes	0	5	4
290	R:R:H230	R:R:R233	1.13	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:V45	4.4275	4	1	5
2	R:R:F49	5.294	5	1	7
3	R:R:I67	4.31	4	0	7
4	R:R:T87	5.45	4	0	8
5	R:R:F91	5.264	5	1	7
6	R:R:F98	8.84333	6	1	6
7	R:R:Y120	5.84	4	2	6
8	R:R:Q123	5.198	5	2	4
9	R:R:Q127	8.185	4	4	6
10	R:R:Y142	6.1775	4	3	4
11	R:R:R153	5.3475	4	3	4
12	R:R:R154	7.92333	6	3	7
13	R:R:H181	13.525	4	0	5
14	R:R:F195	9.728	5	2	6
15	R:R:F204	6.1825	4	2	5
16	R:R:N208	5.8925	4	2	5
17	R:R:L212	6.3	4	0	6
18	R:R:Y213	4.36167	6	7	8
19	R:R:Y224	10.102	5	6	9
20	R:R:F272	4.26	5	0	9
21	R:R:W276	8.764	5	1	8
22	R:R:Y302	7.126	5	8	5
23	R:R:Y313	7.775	6	1	7
24	R:R:L322	4.63	4	5	8
25	R:R:Y323	6.36333	6	5	9
26	R:R:F330	6.126	5	0	8
27	L:L:R219	6.102	5	2	0
28	L:L:F220	6.874	5	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:P46	R:R:V45	13.2347	3.53	No	Yes	0	6	5
2	R:R:F49	R:R:V45	15.9764	5.24	Yes	Yes	1	7	5
3	R:R:F49	R:R:Y313	14.3287	9.28	Yes	Yes	1	7	7
4	R:R:F91	R:R:Y313	73.9248	4.13	Yes	Yes	1	7	7
5	R:R:F91	R:R:S316	50.0819	6.61	Yes	No	0	7	9
6	R:R:F91	R:R:W276	100	5.01	Yes	Yes	1	7	8
7	R:R:F272	R:R:W276	72.0999	8.02	Yes	Yes	0	9	8
8	R:R:F272	R:R:L133	62.9136	3.65	Yes	No	0	9	8
9	R:R:L133	R:R:Y323	62.3245	4.69	No	Yes	0	8	9
10	R:R:M136	R:R:Y323	83.7711	5.99	No	Yes	0	9	9
11	R:R:L84	R:R:M136	82.1101	5.65	No	No	0	9	9
12	R:R:L84	R:R:T132	80.4314	4.42	No	No	0	9	8
13	R:R:T132	R:R:T87	78.7439	9.42	No	Yes	0	8	8
14	R:R:T87	R:R:W167	14.2269	4.85	Yes	No	0	8	9
15	R:R:T90	R:R:W167	10.2051	8.49	No	No	0	6	9
16	R:R:N315	R:R:W276	62.9756	13.56	No	Yes	0	9	8
17	R:R:N315	R:R:N319	59.441	10.9	No	No	0	9	9
18	R:R:N319	R:R:Y323	58.9007	3.49	No	Yes	0	9	9
19	R:R:D88	R:R:S316	44.0138	8.83	No	No	0	9	9
20	R:R:D88	R:R:N60	42.7736	12.12	No	No	0	9	9
21	R:R:A85	R:R:N60	38.9999	4.69	No	No	0	9	9
22	R:R:F330	R:R:V66	11.8661	5.24	Yes	No	0	8	7
23	R:R:F330	R:R:V63	36.4397	6.55	Yes	No	0	8	9
24	R:R:A85	R:R:V63	37.7242	3.39	No	No	0	9	9
25	R:R:F330	R:R:I67	21.7877	3.77	Yes	Yes	0	8	7
26	R:R:I67	R:R:N78	14.7451	5.66	Yes	No	0	7	8
27	R:R:M73	R:R:N78	11.8661	9.82	No	No	0	7	8
28	R:R:N83	R:R:T87	63.1572	4.39	No	Yes	0	9	8
29	R:R:N83	R:R:S163	61.3811	10.43	No	No	0	9	8
30	R:R:F79	R:R:S163	59.5961	2.64	No	No	0	6	8
31	R:R:A159	R:R:F79	54.1879	5.55	No	No	0	7	6
32	R:R:A159	R:R:Y80	52.3675	4	No	No	0	7	7
33	R:R:D139	R:R:Y80	46.8397	10.34	No	No	0	8	7
34	R:R:D139	R:R:R154	43.0217	14.29	No	Yes	3	8	7
35	L:L:L218	R:R:F98	29.1048	4.87	No	Yes	0	0	6
36	R:R:F98	R:R:L101	50.2237	8.53	Yes	No	0	6	4
37	L:L:N214	R:R:L101	47.7344	6.87	No	No	0	0	4
38	L:L:L218	R:R:N119	25.6633	6.87	No	No	0	0	5
39	R:R:C115	R:R:N119	18.634	3.15	No	No	0	9	5
40	R:R:C115	R:R:W108	14.0276	3.92	No	No	0	9	8
41	R:R:P185	R:R:S184	13.6289	1.78	No	No	0	2	3
42	R:R:S184	R:R:Y190	16.5611	5.09	No	No	0	3	4
43	L:L:W213	R:R:Y190	18.0139	2.89	No	No	0	0	4
44	L:L:W213	R:R:R297	19.4579	12	No	No	0	0	2
45	L:L:F216	R:R:R297	34.7566	9.62	No	No	0	0	2
46	L:L:F216	R:R:Y302	36.0943	5.16	No	Yes	0	0	5
47	L:L:S215	R:R:Y302	41.3562	6.36	No	Yes	0	0	5
48	L:L:N212	L:L:S215	42.6496	8.94	No	No	0	0	0
49	L:L:N212	L:L:N214	43.9341	5.45	No	No	0	0	0
50	R:R:H181	R:R:N119	24.2681	28.06	Yes	No	0	5	5
51	L:L:R219	R:R:H181	18.2088	3.39	Yes	Yes	0	0	5
52	L:L:R219	R:R:Q123	11.6446	7.01	Yes	Yes	2	0	4
53	R:R:Q123	R:R:S174	20.326	5.78	Yes	No	2	4	7
54	R:R:S174	R:R:Y120	10.1741	3.82	No	Yes	2	7	6
55	L:L:R219	R:R:F204	13.465	7.48	Yes	Yes	2	0	5
56	R:R:V126	R:R:W276	63.8437	8.58	No	Yes	0	7	8
57	R:R:L212	R:R:V126	19.1522	4.47	Yes	No	0	6	7
58	R:R:L212	R:R:N208	11.8173	8.24	Yes	Yes	0	6	5
59	L:L:F220	R:R:V126	45.3603	13.11	Yes	No	0	0	7
60	R:R:L212	R:R:Q127	10.2272	9.32	Yes	Yes	0	6	6
61	R:R:R140	R:R:Y323	35.5805	8.23	No	Yes	0	9	9
62	R:R:R140	R:R:Y224	33.8043	10.29	No	Yes	0	9	9
63	R:R:R154	R:R:Y142	29.818	3.09	Yes	Yes	3	7	4
64	R:R:F146	R:R:Y142	16.0783	8.25	No	Yes	0	6	4
65	R:R:F146	R:R:V145	12.0742	10.49	No	No	0	6	7
66	R:R:R153	R:R:Y142	10.1785	8.23	Yes	Yes	3	4	4
67	R:R:E201	R:R:F195	10.9182	19.82	No	Yes	0	4	6
68	R:R:F272	R:R:Y213	14.2933	3.09	Yes	Yes	0	9	8
69	R:R:V265	R:R:Y224	16.2245	20.19	No	Yes	0	8	9
70	R:R:L228	R:R:V265	14.2224	4.47	No	No	0	5	8
71	R:R:H295	R:R:R297	15.0994	5.64	No	No	0	3	2
72	R:R:H295	R:R:P296	10.6613	7.63	No	No	0	3	3
73	R:R:F98	R:R:Y313	51.6942	4.13	Yes	Yes	1	6	7
74	L:L:F220	L:L:R219	33.9859	5.34	Yes	Yes	2	0	0
75	R:R:N208	R:R:Q123	17.1192	3.96	Yes	Yes	2	5	4
76	R:R:F195	R:R:F204	12.5836	6.43	Yes	Yes	2	6	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:F49	R:R:F98	4.29	1	Yes	Yes	7	6	2	1
R:R:F49	R:R:L102	4.87	1	Yes	No	7	5	2	2
R:R:F49	R:R:Y313	9.28	1	Yes	Yes	7	7	2	2
R:R:P97	R:R:V118	5.3	0	No	No	9	5	2	1
R:R:F98	R:R:L101	8.53	1	Yes	No	6	4	1	1
R:R:F98	R:R:L102	9.74	1	Yes	No	6	5	1	2
R:R:F98	R:R:H309	21.5	1	Yes	No	6	6	1	2
R:R:F98	R:R:Y313	4.13	1	Yes	Yes	6	7	1	2
L:L:L218	R:R:F98	4.87	0	No	Yes	0	6	0	1
L:L:N214	R:R:L101	6.87	0	No	No	0	4	0	1
L:L:G217	R:R:L101	3.42	0	No	No	0	4	0	1
L:L:N214	R:R:G107	5.09	0	No	No	0	5	0	1
L:L:L218	R:R:V118	7.45	0	No	No	0	5	0	1
R:R:H181	R:R:N119	28.06	0	Yes	No	5	5	1	1
L:L:L218	R:R:N119	6.87	0	No	No	0	5	0	1
R:R:Q123	R:R:S174	5.78	2	Yes	No	4	7	1	2
R:R:Q123	R:R:V177	5.73	2	Yes	No	4	5	1	2
R:R:F204	R:R:Q123	3.51	2	Yes	Yes	5	4	1	1
R:R:N208	R:R:Q123	3.96	2	Yes	Yes	5	4	1	1
L:L:R219	R:R:Q123	7.01	2	Yes	Yes	0	4	0	1
R:R:L212	R:R:V126	4.47	0	Yes	No	6	7	2	1
R:R:V126	R:R:W276	8.58	0	No	Yes	7	8	1	2
L:L:F220	R:R:V126	13.11	2	Yes	No	0	7	0	1
R:R:H181	R:R:L180	11.57	0	Yes	No	5	4	1	2
R:R:F195	R:R:L180	13.4	2	Yes	No	6	4	2	2
R:R:F204	R:R:L180	7.31	2	Yes	No	5	4	1	2
R:R:E193	R:R:H181	11.08	0	No	Yes	4	5	2	1
L:L:R219	R:R:H181	3.39	2	Yes	Yes	0	5	0	1
R:R:S184	R:R:Y190	5.09	0	No	No	3	4	2	1
R:R:E193	R:R:F195	4.66	0	No	Yes	4	6	2	2
R:R:F195	R:R:F204	6.43	2	Yes	Yes	6	5	2	1
L:L:R219	R:R:F204	7.48	2	Yes	Yes	0	5	0	1
R:R:L212	R:R:N208	8.24	0	Yes	Yes	6	5	2	1
R:R:L283	R:R:N208	4.12	2	No	Yes	5	5	1	1
L:L:F220	R:R:N208	7.25	2	Yes	Yes	0	5	0	1
L:L:F220	R:R:I279	5.02	2	Yes	No	0	7	0	1
L:L:R219	R:R:L283	7.29	2	Yes	No	0	5	0	1
L:L:F220	R:R:L283	3.65	2	Yes	No	0	5	0	1
R:R:H295	R:R:R297	5.64	0	No	No	3	2	2	1
L:L:W213	R:R:R297	12	0	No	No	0	2	0	1
L:L:F216	R:R:R297	9.62	0	No	No	0	2	0	1
R:R:Y299	R:R:Y302	5.96	8	No	Yes	4	5	1	1
L:L:Y211	R:R:Y299	13.9	8	No	No	0	4	0	1
R:R:T306	R:R:Y302	6.24	0	No	Yes	4	5	2	1
L:L:Y211	R:R:Y302	11.91	8	No	Yes	0	5	0	1
L:L:S215	R:R:Y302	6.36	0	No	Yes	0	5	0	1
L:L:F216	R:R:Y302	5.16	0	No	Yes	0	5	0	1
R:R:H309	R:R:Y313	11.98	1	No	Yes	6	7	2	2
R:R:A308	R:R:I279	3.25	0	No	No	6	7	2	1
R:R:C115	R:R:N119	3.15	0	No	No	9	5	2	1
L:L:W213	R:R:Y190	2.89	0	No	No	0	4	0	1
R:R:G107	R:R:R188	1.5	0	No	No	5	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8ZJD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.39
Number of Linked Nodes	273
Number of Links	290
Number of Hubs	28
Number of Links mediated by Hubs	111
Number of Communities	8
Number of Nodes involved in Communities	44
Number of Links involved in Communities	55

Path Summary
Number Of Nodes in MetaPath	77
Number Of Links MetaPath	76
Number of Shortest Paths	50792
Length Of Smallest Path	3
Average Path Length	15.5989
Length of Longest Path	38
Minimum Path Strength	1.21
Average Path Strength	6.78426
Maximum Path Strength	22.58
Minimum Path Correlation	0.7
Average Path Correlation	0.937304
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	52.578
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.7608
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q969F8
Sequence	>8ZJD_nogp_Chain_R A W L V P L F F A A L M L L G L V G N S L V I Y V I C R H K P M R T V T N F Y I A N L A A T D V T F L L C C V P F T A L L Y P L P G W V L G D F M C K F V N Y I Q Q V S V Q A T C W T L T A M S V D R W Y V T V F P L R A L H R R T P R L A L A V S L S I W V G S A A V S A P V L A L H R L S P G P R A Y C S E A F P S R A L E R A F A L Y N L L A L Y L L P L L A T C A C Y A A M L R H L G R V S A L Q G Q V L A E R A G A V R A K V S R L V A A V V L L F A A C W G P I Q L F L V L Q A L G P W H P R S Y A A Y A L K T W A H C M S Y S N S A L N P L L Y A F L G S H F R Q A F R R V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8XGS	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	Metastin	-	chim(NtGi1-Gq)/β1/γ2	2.95	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8XGS (No Gprot)	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	Metastin	-		2.95	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8XGO	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK448	-	chim(NtGi1-Gq)/β1/γ2	2.68	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8XGO (No Gprot)	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK448	-		2.68	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8XGU	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK448	-	Gi1/β1/γ2	3	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8XGU (No Gprot)	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK448	-		3	2024-10-30	doi.org/10.1126/sciadv.adn7771
	8ZJE	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK-448	-	chim(NtGi1-Gq)/β1/γ1	3.07	2024-07-03	To be published
	8ZJE (No Gprot)	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	TAK-448	-		3.07	2024-07-03	To be published
	8ZJD	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	Kisspeptin-10	-	chim(NtGi1-Gq)/β1/γ1	3.06	2024-07-03	To be published
	8ZJD (No Gprot)	A	Peptide	Kisspeptin	Kiss1	Homo sapiens	Kisspeptin-10	-		3.06	2024-07-03	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ZJD_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.