psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F5	R:R:Y6	15.47	Yes	Yes	1	4	6
2	R:R:F5	R:R:V188	3.93	Yes	No	0	4	3
3	R:R:E295	R:R:F5	7	No	Yes	0	1	4
4	R:R:F5	R:R:R298	5.34	Yes	No	1	4	1
5	R:R:E301	R:R:F5	3.5	Yes	Yes	1	3	4
6	R:R:E302	R:R:F5	10.49	Yes	Yes	1	3	4
7	R:R:V175	R:R:Y6	10.09	No	Yes	1	4	6
8	R:R:Y177	R:R:Y6	7.94	Yes	Yes	1	9	6
9	R:R:Q186	R:R:Y6	4.51	Yes	Yes	1	5	6
10	R:R:E302	R:R:Y6	5.61	Yes	Yes	1	3	6
11	R:R:E15	R:R:R7	4.65	No	No	0	3	4
12	R:R:C178	R:R:R7	4.18	No	No	0	4	4
13	R:R:R298	R:R:R7	9.6	No	No	0	1	4
14	R:R:C8	R:R:T11	8.45	No	No	3	9	4
15	R:R:C8	R:R:E15	4.56	No	No	3	9	3
16	R:R:N10	R:R:Q9	7.92	No	No	0	6	2
17	R:R:N10	R:R:R94	6.03	No	No	0	6	2
18	R:R:E15	R:R:T11	4.23	No	No	3	3	4
19	R:R:T12	R:R:V95	7.93	No	No	0	5	2
20	R:R:T181	R:R:V14	3.17	Yes	No	0	9	4
21	R:R:K16	R:R:N90	4.2	No	No	0	1	5
22	R:R:N18	R:R:Y87	5.81	No	Yes	0	3	8
23	R:R:S19	R:R:V21	6.46	No	No	0	6	3
24	R:R:A20	R:R:Y87	5.34	No	Yes	0	6	8
25	R:R:M22	R:R:R310	8.69	No	Yes	0	3	9
26	R:R:F27	R:R:L31	4.87	Yes	No	0	8	6
27	R:R:F27	R:R:K76	3.72	Yes	No	0	8	8
28	R:R:F27	R:R:S80	15.85	Yes	Yes	0	8	8
29	R:R:G30	R:R:I317	7.05	No	Yes	0	9	9
30	R:R:L31	R:R:L35	6.92	No	No	0	6	5
31	R:R:D72	R:R:N34	6.73	Yes	No	0	9	9
32	R:R:L73	R:R:N34	6.87	No	No	0	8	9
33	R:R:N34	R:R:P320	4.89	No	No	0	9	9
34	R:R:A37	R:R:I324	3.25	No	Yes	0	9	9
35	R:R:I324	R:R:L40	4.28	Yes	No	0	9	8
36	R:R:L40	R:R:S328	6.01	No	No	0	8	7
37	R:R:L41	R:R:Y62	5.86	No	No	0	9	7
38	R:R:C66	R:R:L41	3.17	No	No	0	6	9
39	R:R:I324	R:R:L41	4.28	Yes	No	0	9	9
40	R:R:P56	R:R:S44	8.91	No	No	0	3	7
41	R:R:L57	R:R:P58	3.28	No	No	0	7	6
42	R:R:L146	R:R:P58	3.28	No	No	0	4	6
43	R:R:E129	R:R:V60	4.28	No	Yes	0	9	7
44	R:R:I144	R:R:V60	4.61	No	Yes	0	5	7
45	R:R:F61	R:R:V65	7.87	No	No	4	9	8
46	R:R:F61	R:R:M126	3.73	No	Yes	4	9	9
47	R:R:L146	R:R:M63	4.24	No	No	0	4	6
48	R:R:A150	R:R:M63	3.22	No	No	0	5	6
49	R:R:L64	R:R:M126	5.65	No	Yes	0	8	9
50	R:R:M126	R:R:V65	4.56	Yes	No	4	9	8
51	R:R:I324	R:R:V65	3.07	Yes	No	0	9	8
52	R:R:D72	R:R:L68	8.14	Yes	Yes	2	9	9
53	R:R:L68	R:R:Q122	6.65	Yes	No	0	9	7
54	R:R:L123	R:R:L68	5.54	No	Yes	2	8	9
55	R:R:D319	R:R:L68	6.79	Yes	Yes	2	9	9
56	R:R:S118	R:R:T71	4.8	No	No	0	7	9
57	R:R:Q122	R:R:T71	7.09	No	No	0	7	9
58	R:R:D72	R:R:S119	4.42	Yes	No	0	9	8
59	R:R:D72	R:R:S316	10.31	Yes	No	0	9	8
60	R:R:D319	R:R:D72	3.99	Yes	Yes	2	9	9
61	R:R:C77	R:R:L73	3.17	No	No	0	6	8
62	R:R:F115	R:R:G75	9.03	Yes	No	0	8	9
63	L:L:?1	R:R:K76	9.25	Yes	No	0	0	8
64	R:R:F108	R:R:L79	8.53	Yes	No	1	6	6
65	R:R:L79	R:R:M112	4.24	No	Yes	1	6	8
66	L:L:?1	R:R:L79	9.08	Yes	No	1	0	6
67	R:R:P81	R:R:S80	3.56	No	Yes	0	8	8
68	L:L:?1	R:R:S80	8.2	Yes	Yes	0	0	8
69	R:R:L104	R:R:V82	5.96	No	No	0	5	6
70	R:R:F108	R:R:V82	5.24	Yes	No	0	6	6
71	R:R:F108	R:R:V83	3.93	Yes	No	0	6	9
72	R:R:T181	R:R:V83	4.76	Yes	No	0	9	9
73	L:L:?1	R:R:V83	6.51	Yes	No	0	0	9
74	R:R:A85	R:R:L96	3.15	No	No	0	6	4
75	R:R:A86	R:R:T181	3.36	No	Yes	0	6	9
76	R:R:T181	R:R:Y87	19.97	Yes	Yes	0	9	8
77	L:L:?1	R:R:Y87	3.84	Yes	Yes	0	0	8
78	R:R:A88	R:R:Q89	4.55	No	No	0	5	5
79	R:R:Q89	R:R:R91	7.01	No	No	0	5	3
80	R:R:S92	R:R:V95	4.85	No	No	0	5	2
81	R:R:Q176	R:R:S92	7.22	No	No	0	5	5
82	R:R:F108	R:R:L93	4.87	Yes	No	0	6	6
83	R:R:C183	R:R:L93	4.76	No	No	0	9	6
84	R:R:A97	R:R:L100	3.15	No	No	0	1	4
85	R:R:L100	R:R:S103	10.51	No	No	0	4	3
86	R:R:D101	R:R:N102	9.42	No	No	0	4	1
87	R:R:C105	R:R:C183	5.46	No	No	0	9	9
88	R:R:F174	R:R:Q106	5.86	Yes	No	0	6	4
89	R:R:F108	R:R:M112	3.73	Yes	Yes	1	6	8
90	R:R:A109	R:R:F174	9.71	No	Yes	0	8	6
91	R:R:F110	R:R:F168	10.72	No	No	0	7	4
92	R:R:F111	R:R:F115	3.22	No	Yes	5	5	8
93	R:R:F184	R:R:M112	6.22	Yes	Yes	1	8	8
94	L:L:?1	R:R:M112	6.95	Yes	Yes	1	0	8
95	R:R:F184	R:R:S113	3.96	Yes	No	1	8	7
96	R:R:I185	R:R:S113	3.1	Yes	No	1	7	7
97	R:R:S113	R:R:Y203	3.82	No	Yes	1	7	8
98	R:R:F114	R:R:F115	15	Yes	Yes	0	7	8
99	R:R:F114	R:R:S160	3.96	Yes	No	0	7	7
100	R:R:F114	R:R:L161	7.31	Yes	No	0	7	3
101	R:R:L117	R:R:L121	5.54	Yes	Yes	0	8	5
102	R:R:L117	R:R:S160	6.01	Yes	No	0	8	7
103	R:R:F163	R:R:L117	3.65	Yes	Yes	1	7	8
104	R:R:L117	R:R:L206	5.54	Yes	No	1	8	5
105	R:R:S118	R:R:S160	3.26	No	No	0	7	7
106	R:R:M207	R:R:T120	7.53	No	No	0	7	7
107	R:R:L210	R:R:T120	5.9	Yes	No	0	6	7
108	R:R:F274	R:R:T120	5.19	Yes	No	0	9	7
109	R:R:L121	R:R:V156	7.45	Yes	No	0	5	6
110	R:R:L121	R:R:L210	5.54	Yes	Yes	0	5	6
111	R:R:F274	R:R:L123	4.87	Yes	No	2	9	8
112	R:R:D319	R:R:L123	8.14	Yes	No	2	9	8
113	R:R:L124	R:R:L210	4.15	No	Yes	0	5	6
114	R:R:A213	R:R:L124	4.73	No	No	0	6	5
115	R:R:L124	R:R:T214	5.9	No	No	0	5	8
116	R:R:F323	R:R:M126	4.98	No	Yes	0	9	9
117	R:R:A127	R:R:N218	3.13	No	No	0	9	9
118	R:R:L128	R:R:L132	5.54	No	No	0	7	5
119	R:R:C217	R:R:L128	3.17	No	No	0	7	7
120	R:R:E129	R:R:Y140	7.86	No	No	0	9	8
121	R:R:C130	R:R:L134	3.17	No	No	0	9	8
122	R:R:L132	R:R:W131	5.69	No	No	0	5	6
123	R:R:H136	R:R:W131	8.46	No	No	0	4	6
124	R:R:F139	R:R:L132	3.65	No	No	0	5	5
125	R:R:S133	R:R:Y140	13.99	No	No	0	9	8
126	R:R:L134	R:R:L225	5.54	No	Yes	6	8	9
127	R:R:G135	R:R:H136	3.18	No	No	0	7	4
128	R:R:G135	R:R:N224	5.09	No	No	0	7	7
129	R:R:F139	R:R:H143	16.97	No	No	0	5	5
130	R:R:I144	R:R:Y140	10.88	No	No	0	5	8
131	R:R:H143	R:R:R142	5.64	No	No	0	5	5
132	R:R:R147	R:R:T145	3.88	No	No	0	4	6
133	R:R:L151	R:R:R147	6.07	No	No	0	3	4
134	R:R:F163	R:R:Y199	4.13	Yes	Yes	1	7	6
135	R:R:F163	R:R:L202	6.09	Yes	No	0	7	5
136	R:R:F163	R:R:Y203	4.13	Yes	Yes	1	7	8
137	R:R:F163	R:R:L206	4.87	Yes	No	1	7	5
138	R:R:F171	R:R:L166	3.65	No	No	1	4	7
139	R:R:L166	R:R:Y199	5.86	No	Yes	1	7	6
140	R:R:G172	R:R:P167	4.06	No	No	1	8	9
141	R:R:F174	R:R:P167	8.67	Yes	No	0	6	9
142	R:R:P167	R:R:Y199	13.91	No	Yes	1	9	6
143	R:R:F168	R:R:F174	4.29	No	Yes	0	4	6
144	R:R:F171	R:R:Y199	9.28	No	Yes	1	4	6
145	R:R:G172	R:R:Y199	4.35	No	Yes	1	8	6
146	R:R:K173	R:R:Q186	8.14	No	Yes	1	2	5
147	R:R:K173	R:R:V196	7.59	No	No	1	2	5
148	R:R:F174	R:R:I185	5.02	Yes	Yes	0	6	7
149	R:R:Q186	R:R:V175	8.6	Yes	No	1	5	4
150	R:R:G180	R:R:Q176	6.58	No	No	0	6	5
151	R:R:C183	R:R:Q176	4.58	No	No	0	9	5
152	R:R:W182	R:R:Y177	25.08	Yes	Yes	1	9	9
153	R:R:F184	R:R:Y177	5.16	Yes	Yes	1	8	9
154	R:R:M187	R:R:Y177	3.59	No	Yes	1	7	9
155	R:R:E302	R:R:Y177	5.61	Yes	Yes	1	3	9
156	R:R:D305	R:R:Y177	5.75	No	Yes	0	7	9
157	R:R:C178	R:R:E302	6.08	No	Yes	0	4	3
158	R:R:P179	R:R:W182	6.76	No	Yes	1	8	9
159	R:R:L306	R:R:P179	4.93	No	No	1	7	8
160	R:R:L306	R:R:W182	5.69	No	Yes	1	7	9
161	R:R:L309	R:R:W182	4.56	No	Yes	0	7	9
162	L:L:?1	R:R:W182	8.71	Yes	Yes	1	0	9
163	R:R:F184	R:R:I185	7.54	Yes	Yes	1	8	7
164	R:R:F184	R:R:M187	3.73	Yes	No	1	8	7
165	R:R:F184	R:R:L309	6.09	Yes	No	0	8	7
166	R:R:I185	R:R:Y199	9.67	Yes	Yes	1	7	6
167	R:R:I185	R:R:S200	4.64	Yes	No	0	7	7
168	R:R:I185	R:R:Y203	4.84	Yes	Yes	1	7	8
169	R:R:H189	R:R:Q186	3.71	Yes	Yes	1	4	5
170	R:R:Q186	R:R:V196	8.6	Yes	No	1	5	5
171	R:R:G288	R:R:V188	5.52	No	No	0	7	3
172	R:R:E191	R:R:H189	12.31	No	Yes	1	1	4
173	R:R:G192	R:R:H189	4.77	No	Yes	1	1	4
174	R:R:H189	R:R:S193	8.37	Yes	Yes	1	4	3
175	R:R:E191	R:R:G192	3.27	No	No	1	1	1
176	R:R:E191	R:R:S193	5.75	No	Yes	1	1	3
177	R:R:S193	R:R:S195	4.89	Yes	No	0	3	1
178	R:R:S193	R:R:V196	6.46	Yes	No	1	3	5
179	R:R:A289	R:R:L197	3.15	No	No	0	7	4
180	R:R:F290	R:R:V201	5.24	No	No	0	3	4
181	R:R:M207	R:R:Y203	10.78	No	Yes	0	7	8
182	R:R:I282	R:R:S204	4.64	Yes	No	7	8	8
183	R:R:A285	R:R:S204	3.42	No	No	0	7	8
184	R:R:S204	R:R:Y286	13.99	No	No	7	8	5
185	R:R:S205	R:R:Y286	5.09	No	No	0	4	5
186	R:R:L206	R:R:L210	6.92	No	Yes	0	5	6
187	R:R:A208	R:R:I282	3.25	No	Yes	0	6	8
188	R:R:F274	R:R:V211	7.87	Yes	No	2	9	8
189	R:R:S278	R:R:V211	3.23	No	No	2	9	8
190	R:R:L212	R:R:L216	4.15	No	No	0	3	4
191	R:R:N218	R:R:T214	4.39	No	No	0	9	8
192	R:R:T271	R:R:V215	4.76	No	No	0	8	6
193	R:R:N218	R:R:T271	13.16	No	No	0	9	8
194	R:R:L264	R:R:M222	7.07	No	No	0	7	7
195	R:R:L225	R:R:L264	4.15	Yes	No	0	9	7
196	R:R:R230	R:R:Y226	14.4	No	No	0	5	5
197	R:R:M228	R:R:R231	3.72	No	No	0	8	5
198	R:R:H229	R:R:Q233	13.6	No	No	0	6	3
199	R:R:E260	R:R:H229	12.31	Yes	No	0	9	6
200	R:R:H229	R:R:L261	16.71	No	No	0	6	5
201	R:R:R231	R:R:R234	4.26	No	No	0	5	3
202	R:R:E260	R:R:L232	7.95	Yes	No	0	9	5
203	R:R:H235	R:R:P236	21.35	No	No	0	4	4
204	R:R:P257	R:R:Q256	3.16	No	No	0	6	5
205	R:R:Q256	R:R:R332	8.18	No	No	0	5	6
206	R:R:D262	R:R:L258	9.5	No	No	8	9	6
207	R:R:H263	R:R:L258	9	No	No	8	8	6
208	R:R:L258	R:R:R332	9.72	No	No	0	6	6
209	R:R:D262	R:R:E259	3.9	No	No	0	9	6
210	R:R:D262	R:R:H263	8.82	No	No	8	9	8
211	R:R:H263	R:R:R327	7.9	No	No	0	8	9
212	R:R:L266	R:R:R327	7.29	No	No	0	8	9
213	R:R:I322	R:R:M270	5.83	Yes	No	0	8	9
214	R:R:F323	R:R:M270	7.46	No	No	0	9	9
215	R:R:L273	R:R:V318	5.96	No	No	0	8	8
216	R:R:F274	R:R:S278	9.25	Yes	No	2	9	9
217	R:R:F274	R:R:I315	5.02	Yes	No	0	9	9
218	R:R:M276	R:R:T275	4.52	No	No	0	5	5
219	R:R:C277	R:R:V314	3.42	No	No	0	9	4
220	R:R:C277	R:R:I315	4.91	No	No	0	9	9
221	R:R:L312	R:R:V281	4.47	No	No	0	8	8
222	R:R:I282	R:R:Y286	4.84	Yes	No	7	8	5
223	R:R:E301	R:R:R284	12.79	Yes	No	1	3	5
224	R:R:E304	R:R:R284	17.45	No	No	1	1	5
225	R:R:D305	R:R:R284	13.1	No	No	0	7	5
226	R:R:K291	R:R:Y287	7.17	No	Yes	0	3	4
227	R:R:D292	R:R:Y287	8.05	Yes	Yes	1	2	4
228	R:R:E301	R:R:Y287	5.61	Yes	Yes	1	3	4
229	R:R:A289	R:R:F290	8.32	No	No	0	7	3
230	R:R:D292	R:R:E295	9.09	Yes	No	0	2	1
231	R:R:D292	R:R:E301	6.5	Yes	Yes	1	2	3
232	R:R:K294	R:R:K296	4.31	No	No	0	1	1
233	R:R:N297	R:R:T299	4.39	No	No	0	3	1
234	R:R:N297	R:R:S300	4.47	No	No	0	3	1
235	R:R:E302	R:R:R298	4.65	Yes	No	1	3	1
236	R:R:E304	R:R:S300	4.31	No	No	0	1	1
237	R:R:E301	R:R:E304	3.81	Yes	No	1	3	1
238	R:R:L306	R:R:R310	14.58	No	Yes	0	7	9
239	R:R:R307	R:R:R310	3.2	No	Yes	0	4	9
240	R:R:F311	R:R:R307	5.34	No	No	0	6	4
241	L:L:?1	R:R:R310	7.97	Yes	Yes	0	0	9
242	L:L:?1	R:R:S313	8.2	Yes	No	0	0	9
243	R:R:D319	R:R:I315	4.2	Yes	No	0	9	9
244	R:R:I322	R:R:V318	3.07	Yes	No	0	8	8
245	R:R:D319	R:R:F323	7.17	Yes	No	0	9	9
246	R:R:I325	R:R:W321	15.27	No	No	0	8	8
247	R:R:F326	R:R:W321	5.01	No	No	0	5	8
248	R:R:F326	R:R:I322	5.02	No	Yes	0	5	8
249	R:R:F331	R:R:I325	6.28	No	No	0	7	8
250	R:R:F326	R:R:F331	5.36	No	No	0	5	7
251	R:R:P329	R:R:S328	3.56	No	No	0	7	7
252	R:R:S328	R:R:V330	3.23	No	No	0	7	7
253	R:R:P329	R:R:R332	5.76	No	No	0	7	6
254	R:R:F331	R:R:F335	9.65	No	No	0	7	4
255	R:R:F334	R:R:I333	3.77	No	No	0	4	5
256	R:R:I317	R:R:T29	3.04	Yes	No	0	9	6
257	L:L:?1	R:R:L312	3.03	Yes	No	0	0	8
258	R:R:F171	R:R:G198	3.01	No	No	0	4	4
259	R:R:L84	R:R:S80	3	No	Yes	0	7	8
260	R:R:L64	R:R:V60	2.98	No	Yes	0	8	7
261	R:R:L64	R:R:V152	2.98	No	No	0	8	5
262	R:R:L219	R:R:V215	2.98	No	No	0	5	6
263	R:R:Y283	R:R:Y287	2.98	No	Yes	0	6	4
264	R:R:L38	R:R:T69	2.95	No	No	0	7	8
265	R:R:I282	R:R:M207	2.92	Yes	No	0	8	7
266	R:R:I317	R:R:K76	2.91	Yes	No	0	9	8
267	R:R:I317	R:R:L26	2.85	Yes	No	0	9	8
268	R:R:I325	R:R:L36	2.85	No	No	0	8	5
269	R:R:G220	R:R:W131	2.81	No	No	0	5	6
270	L:L:?1	R:R:G23	2.8	Yes	No	0	0	8
271	R:R:C105	R:R:R94	2.79	No	No	0	9	2
272	R:R:C164	R:R:F110	2.79	No	No	0	8	7
273	R:R:C164	R:R:F114	2.79	No	Yes	0	8	7
274	R:R:L104	R:R:L96	2.77	No	No	0	5	4
275	R:R:D292	R:R:K296	2.77	Yes	No	0	2	1
276	R:R:L96	R:R:Q89	2.66	No	No	0	4	5
277	R:R:E260	R:R:L225	2.65	Yes	Yes	0	9	9
278	R:R:S44	R:R:Y62	2.54	No	No	0	7	7
279	R:R:S59	R:R:Y62	2.54	No	No	0	7	7
280	R:R:E259	R:R:E260	2.54	No	Yes	0	6	9
281	R:R:F139	R:R:I144	2.51	No	No	0	5	5
282	R:R:F290	R:R:K291	2.48	No	No	0	3	3
283	R:R:E190	R:R:H189	2.46	No	Yes	0	1	4
284	R:R:F115	R:R:L74	2.44	Yes	No	0	8	4
285	R:R:F111	R:R:L78	2.44	No	No	5	5	6
286	R:R:F115	R:R:L78	2.44	Yes	No	5	8	6
287	R:R:F159	R:R:L121	2.44	No	Yes	0	4	5
288	R:R:N224	R:R:R223	2.41	No	No	0	7	4
289	R:R:Q233	R:R:R230	2.34	No	No	0	3	5
290	R:R:G23	R:R:G24	2.11	No	No	0	8	4
291	R:R:G33	R:R:P320	2.03	No	No	0	9	9
292	R:R:G135	R:R:P137	2.03	No	No	0	7	9
293	R:R:C66	R:R:G67	1.96	No	No	0	6	6
294	R:R:A42	R:R:G39	1.95	No	No	0	4	3
295	R:R:A97	R:R:P98	1.87	No	No	0	1	5
296	L:L:?1	R:R:G116	1.87	Yes	No	0	0	8
297	R:R:A153	R:R:P154	1.87	No	No	0	7	4
298	R:R:A308	R:R:P280	1.87	No	No	0	7	9
299	R:R:G45	R:R:S44	1.86	No	No	0	6	7
300	R:R:G149	R:R:V60	1.84	No	Yes	0	7	7
301	R:R:G67	R:R:V70	1.84	No	No	0	6	5
302	R:R:A221	R:R:C130	1.81	No	No	0	9	9
303	R:R:P4	R:R:S3	1.78	No	No	0	6	6
304	R:R:G17	R:R:K16	1.74	No	No	0	3	1
305	R:R:G33	R:R:L32	1.71	No	No	0	9	4
306	R:R:G47	R:R:L46	1.71	No	No	0	5	4
307	R:R:A107	R:R:S103	1.71	No	No	0	5	3
308	R:R:G149	R:R:L148	1.71	No	No	0	7	5
309	R:R:G17	R:R:N18	1.7	No	No	0	3	3
310	R:R:A125	R:R:V152	1.7	No	No	0	7	5
311	R:R:A308	R:R:V281	1.7	No	No	0	7	8
312	R:R:A37	R:R:T69	1.68	No	No	0	9	8
313	R:R:L279	R:R:P280	1.64	No	No	0	7	9
314	R:R:A165	R:R:M169	1.61	No	No	0	5	3
315	R:R:A268	R:R:M222	1.61	No	No	0	6	7
316	R:R:S13	R:R:T12	1.6	No	No	0	1	5
317	R:R:T29	R:R:V25	1.59	No	No	0	6	4
318	R:R:T275	R:R:V211	1.59	No	No	0	5	8
319	R:R:T275	R:R:V215	1.59	No	No	0	5	6
320	R:R:A97	R:R:L104	1.58	No	No	0	1	5
321	R:R:A221	R:R:L267	1.58	No	No	0	9	9
322	R:R:M276	R:R:V272	1.52	No	No	0	5	5
323	R:R:L146	R:R:V60	1.49	No	Yes	0	4	7
324	R:R:L151	R:R:V155	1.49	No	No	0	3	3
325	R:R:I322	R:R:L269	1.43	Yes	No	0	8	5
326	R:R:L134	R:R:M228	1.41	No	No	6	8	8
327	R:R:L166	R:R:M169	1.41	No	No	0	7	3
328	R:R:L225	R:R:M228	1.41	Yes	No	6	9	8
329	R:R:A227	R:R:R231	1.38	No	No	0	4	5
330	R:R:I333	R:R:Q256	1.37	No	No	0	5	5
331	R:R:F27	R:R:S28	1.32	Yes	No	0	8	4
332	R:R:F114	R:R:S157	1.32	Yes	No	0	7	6
333	R:R:N102	R:R:R94	1.21	No	No	0	1	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:F5	7.62167	6	1	4
2	R:R:Y6	8.724	5	1	6
3	R:R:F27	6.44	4	0	8
4	R:R:V60	3.04	5	0	7
5	R:R:L68	6.78	4	2	9
6	R:R:D72	6.718	5	2	9
7	R:R:S80	7.6525	4	0	8
8	R:R:Y87	8.74	4	0	8
9	R:R:F108	5.26	5	1	6
10	R:R:M112	5.285	4	1	8
11	R:R:F114	6.076	5	0	7
12	R:R:F115	6.426	5	5	8
13	R:R:L117	5.185	4	1	8
14	R:R:L121	5.2425	4	0	5
15	R:R:M126	4.73	4	4	9
16	R:R:F163	4.574	5	1	7
17	R:R:F174	6.71	5	0	6
18	R:R:Y177	8.855	6	1	9
19	R:R:T181	7.815	4	0	9
20	R:R:W182	10.16	5	1	9
21	R:R:F184	5.45	6	1	8
22	R:R:I185	5.80167	6	1	7
23	R:R:Q186	6.712	5	1	5
24	R:R:H189	6.324	5	1	4
25	R:R:S193	6.3675	4	1	3
26	R:R:Y199	7.86667	6	1	6
27	R:R:Y203	5.8925	4	1	8
28	R:R:L210	5.6275	4	0	6
29	R:R:L225	3.4375	4	6	9
30	R:R:E260	6.3625	4	0	9
31	R:R:F274	6.44	5	2	9
32	R:R:I282	3.9125	4	7	8
33	R:R:Y287	5.9525	4	1	4
34	R:R:D292	6.6025	4	1	2
35	R:R:E301	6.442	5	1	3
36	R:R:E302	6.488	5	1	3
37	R:R:R310	8.61	4	0	9
38	R:R:I317	3.9625	4	0	9
39	R:R:D319	6.058	5	2	9
40	R:R:I322	3.8375	4	0	8
41	R:R:I324	3.72	4	0	9
42	L:L:?1	6.3675	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F5	R:R:Y6	14.2107	15.47	Yes	Yes	1	4	6
2	R:R:Y177	R:R:Y6	23.7991	7.94	Yes	Yes	1	9	6
3	R:R:E302	R:R:F5	13.86	10.49	Yes	Yes	1	3	4
4	R:R:E302	R:R:Y177	22.3301	5.61	Yes	Yes	1	3	9
5	R:R:F184	R:R:Y177	57.0478	5.16	Yes	Yes	1	8	9
6	R:R:F184	R:R:M112	54.6149	6.22	Yes	Yes	1	8	8
7	R:R:F108	R:R:M112	24.5871	3.73	Yes	Yes	1	6	8
8	R:R:F108	R:R:L93	13.0393	4.87	Yes	No	0	6	6
9	R:R:C183	R:R:L93	12.1633	4.76	No	No	0	9	6
10	R:R:F274	R:R:L123	51.3613	4.87	Yes	No	2	9	8
11	R:R:F274	R:R:T120	100	5.19	Yes	No	0	9	7
12	R:R:M207	R:R:T120	97.0575	7.53	No	No	0	7	7
13	R:R:M207	R:R:Y203	98.0519	10.78	No	Yes	0	7	8
14	R:R:S113	R:R:Y203	50.5721	3.82	No	Yes	1	7	8
15	R:R:F184	R:R:S113	50.438	3.96	Yes	No	1	8	7
16	R:R:D319	R:R:L123	46.1551	8.14	Yes	No	2	9	8
17	R:R:D319	R:R:I315	46.3941	4.2	Yes	No	0	9	9
18	R:R:F274	R:R:I315	47.4053	5.02	Yes	No	0	9	9
19	R:R:I185	R:R:Y203	54.5777	4.84	Yes	Yes	1	7	8
20	R:R:F184	R:R:I185	59.731	7.54	Yes	Yes	1	8	7
21	R:R:I324	R:R:V65	45.5993	3.07	Yes	No	0	9	8
22	R:R:M126	R:R:V65	46.4775	4.56	Yes	No	4	9	8
23	R:R:F323	R:R:M126	74.6733	4.98	No	Yes	0	9	9
24	R:R:D319	R:R:F323	86.3181	7.17	Yes	No	0	9	9
25	R:R:I324	R:R:L40	33.357	4.28	Yes	No	0	9	8
26	R:R:L40	R:R:S328	32.3942	6.01	No	No	0	8	7
27	R:R:L64	R:R:M126	29.6784	5.65	No	Yes	0	8	9
28	R:R:L64	R:R:V60	26.7731	2.98	No	Yes	0	8	7
29	R:R:I144	R:R:V60	16.0968	4.61	No	Yes	0	5	7
30	R:R:F163	R:R:Y203	12.6132	4.13	Yes	Yes	1	7	8
31	R:R:F108	R:R:V82	11.2411	5.24	Yes	No	0	6	6
32	R:R:L104	R:R:V82	10.3167	5.96	No	No	0	5	6
33	R:R:F139	R:R:I144	13.2186	2.51	No	No	0	5	5
34	R:R:F139	R:R:L132	10.2017	3.65	No	No	0	5	5
35	R:R:E260	R:R:L225	12.1306	2.65	Yes	Yes	0	9	9
36	R:R:E259	R:R:E260	18.9299	2.54	No	Yes	0	6	9
37	R:R:D262	R:R:E259	19.9186	3.9	No	No	0	9	6
38	R:R:D262	R:R:L258	20.8374	9.5	No	No	8	9	6
39	R:R:L258	R:R:R332	24.737	9.72	No	No	0	6	6
40	R:R:P329	R:R:R332	29.5092	5.76	No	No	0	7	6
41	R:R:P329	R:R:S328	30.4732	3.56	No	No	0	7	7
42	R:R:D305	R:R:Y177	13.1385	5.75	No	Yes	0	7	9
43	R:R:D305	R:R:R284	12.4136	13.1	No	No	0	7	5
44	R:R:E301	R:R:F5	17.3166	3.5	Yes	Yes	1	3	4
45	R:R:K291	R:R:Y287	11.8026	7.17	No	Yes	0	3	4
46	R:R:E301	R:R:Y287	16.3572	5.61	Yes	Yes	1	3	4
47	R:R:F323	R:R:M270	13.1318	7.46	No	No	0	9	9
48	R:R:I322	R:R:M270	12.1352	5.83	Yes	No	0	8	9
49	L:L:?1	R:R:M112	31.065	6.95	Yes	Yes	1	0	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:N18	R:R:Y87	5.81	0	No	Yes	3	8	2	1
R:R:A20	R:R:Y87	5.34	0	No	Yes	6	8	2	1
R:R:M22	R:R:R310	8.69	0	No	Yes	3	9	2	1
R:R:F27	R:R:K76	3.72	0	Yes	No	8	8	2	1
R:R:F27	R:R:S80	15.85	0	Yes	Yes	8	8	2	1
L:L:?1	R:R:K76	9.25	1	Yes	No	0	8	0	1
R:R:F108	R:R:L79	8.53	1	Yes	No	6	6	2	1
R:R:L79	R:R:M112	4.24	1	No	Yes	6	8	1	1
L:L:?1	R:R:L79	9.08	1	Yes	No	0	6	0	1
R:R:P81	R:R:S80	3.56	0	No	Yes	8	8	2	1
L:L:?1	R:R:S80	8.2	1	Yes	Yes	0	8	0	1
R:R:F108	R:R:V83	3.93	1	Yes	No	6	9	2	1
R:R:T181	R:R:V83	4.76	0	Yes	No	9	9	2	1
L:L:?1	R:R:V83	6.51	1	Yes	No	0	9	0	1
R:R:T181	R:R:Y87	19.97	0	Yes	Yes	9	8	2	1
L:L:?1	R:R:Y87	3.84	1	Yes	Yes	0	8	0	1
R:R:F108	R:R:M112	3.73	1	Yes	Yes	6	8	2	1
R:R:F184	R:R:M112	6.22	1	Yes	Yes	8	8	2	1
L:L:?1	R:R:M112	6.95	1	Yes	Yes	0	8	0	1
R:R:W182	R:R:Y177	25.08	1	Yes	Yes	9	9	1	2
R:R:F184	R:R:Y177	5.16	1	Yes	Yes	8	9	2	2
R:R:P179	R:R:W182	6.76	1	No	Yes	8	9	2	1
R:R:L306	R:R:P179	4.93	1	No	No	7	8	2	2
R:R:L306	R:R:W182	5.69	1	No	Yes	7	9	2	1
R:R:L309	R:R:W182	4.56	0	No	Yes	7	9	2	1
L:L:?1	R:R:W182	8.71	1	Yes	Yes	0	9	0	1
R:R:F184	R:R:L309	6.09	1	Yes	No	8	7	2	2
R:R:L312	R:R:V281	4.47	0	No	No	8	8	1	2
R:R:L306	R:R:R310	14.58	1	No	Yes	7	9	2	1
R:R:R307	R:R:R310	3.2	0	No	Yes	4	9	2	1
L:L:?1	R:R:R310	7.97	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:S313	8.2	1	Yes	No	0	9	0	1
L:L:?1	R:R:L312	3.03	1	Yes	No	0	8	0	1
R:R:L84	R:R:S80	3	0	No	Yes	7	8	2	1
R:R:I317	R:R:K76	2.91	0	Yes	No	9	8	2	1
L:L:?1	R:R:G23	2.8	1	Yes	No	0	8	0	1
R:R:G23	R:R:G24	2.11	0	No	No	8	4	1	2
L:L:?1	R:R:G116	1.87	1	Yes	No	0	8	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8ZVZ_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.07
Number of Linked Nodes	295
Number of Links	333
Number of Hubs	42
Number of Links mediated by Hubs	164
Number of Communities	8
Number of Nodes involved in Communities	63
Number of Links involved in Communities	85

Path Summary
Number Of Nodes in MetaPath	50
Number Of Links MetaPath	49
Number of Shortest Paths	135669
Length Of Smallest Path	3
Average Path Length	16.4189
Length of Longest Path	34
Minimum Path Strength	1.51
Average Path Strength	5.96278
Maximum Path Strength	16.51
Minimum Path Correlation	0.7
Average Path Correlation	0.927407
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	42.0314
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.7607
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • prostanoid receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • icosanoid receptor activity • prostaglandin D receptor activity • prostaglandin receptor activity • prostaglandin J receptor activity • multicellular organismal process • sleep • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • establishment of organelle localization • regulated exocytosis • cellular localization • response to stimulus • transport • cell activation involved in immune response • leukocyte degranulation • myeloid leukocyte activation • myeloid leukocyte mediated immunity • vesicle-mediated transport • leukocyte activation • localization • secretion by cell • organelle localization • leukocyte activation involved in immune response • establishment of localization in cell • mast cell activation • leukocyte mediated immunity • mast cell mediated immunity • immune response • secretion • cell activation • vacuolar localization • export from cell • mast cell degranulation • establishment of localization • myeloid cell activation involved in immune response • immune effector process • mast cell activation involved in immune response • exocytosis • immune system process • lysosome localization • cellular process • developmental process • multicellular organism development • sex determination • male sex determination • reproductive process • anatomical structure development • developmental process involved in reproduction • defense response • response to stress • inflammatory response • cellular response to stimulus • response to ketone • response to prostaglandin • response to lipid • cellular response to prostaglandin D stimulus • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to prostaglandin D • response to chemical • cellular response to lipid • cellular response to ketone • cellular response to hormone stimulus • regulation of biological process • regulation of cellular process • signaling • G protein-coupled receptor signaling pathway • signal transduction • cell communication • carbohydrate derivative metabolic process • primary metabolic process • nucleoside metabolic process • purine-containing compound metabolic process • nucleobase-containing compound metabolic process • adenosine metabolic process • nucleobase-containing small molecule metabolic process • metabolic process • small molecule metabolic process • purine nucleoside metabolic process • ribonucleoside metabolic process • purine ribonucleoside metabolic process • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin E stimulus • response to prostaglandin E • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • molecular function regulator activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • sensory perception of smell • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • skeletal system development • bone development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • coagulation • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • regulation of protein transport • protein secretion • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	A1A
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	A1A
Name	6-AMINO HEXANOIC ACID
Synonyms
Identifier
Formula	C33 H40 N4 O6
Molecular Weight	588.694
SMILES
PubChem	5327090
Formal Charge	0
Total Atoms	83
Total Chiral Atoms	4
Total Bonds	86
Total Aromatic Bonds	18


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q13258
Sequence	>8ZVZ_nogp_Chain_R S P F Y R C Q N T T S V E K G N S A V M G G V L F S T G L L G N L L A L G L L A R S G L G P L P S V F Y M L V C G L T V T D L L G K C L L S P V V L A A Y A Q N R S L R V L A P A L D N S L C Q A F A F F M S F F G L S S T L Q L L A M A L E C W L S L G H P F F Y R R H I T L R L G A L V A P V V S A F S L A F C A L P F M G F G K F V Q Y C P G T W C F I Q M V H E E G S L S V L G Y S V L Y S S L M A L L V L A T V L C N L G A M R N L Y A M H R R L Q R H P Q P L E E L D H L L L L A L M T V L F T M C S L P V I Y R A Y Y G A F K D V K E K N R T S E E A E D L R A L R F L S V I S I V D P W I F I I F R S P V F R I F F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9UWD	A	Lipid	Prostaglandin	DP₁	Homo sapiens	-	-	-	-	2025-04-09	doi.org/10.1073/pnas.2501902122
	8ZVZ	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-	Gs/β1/γ2	2.35	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZVZ (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-		2.35	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZW0	A	Lipid	Prostaglandin	DP₁	Homo sapiens	PGD2	-	Gs/β1/γ2	2.72	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZW0 (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	PGD2	-		2.72	2025-05-28	doi.org/10.1073/pnas.2501902122
	9AU0	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-	Gs/β1/γ2	2.45	2025-08-27	To be published
	9AU0 (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-		2.45	2025-08-27	To be published

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