psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	H:H:?1	R:R:P4	10.31	No	No	0	0	6
2	H:H:?1	R:R:Q9	23.89	No	No	1	0	2
3	H:H:?1	R:R:N10	27.11	No	No	1	0	6
4	L:L:?1	R:R:G23	3.49	Yes	No	0	0	8
5	L:L:?1	R:R:K76	13.43	Yes	No	1	0	8
6	L:L:?1	R:R:L79	3.77	Yes	No	0	0	6
7	L:L:?1	R:R:S80	13.28	Yes	No	0	0	8
8	L:L:?1	R:R:V83	10.14	Yes	No	1	0	9
9	L:L:?1	R:R:Y87	7.18	Yes	No	1	0	8
10	L:L:?1	R:R:M112	5.77	Yes	Yes	1	0	8
11	L:L:?1	R:R:T181	4.01	Yes	Yes	1	0	9
12	L:L:?1	R:R:W182	5.43	Yes	Yes	1	0	9
13	L:L:?1	R:R:L306	3.77	Yes	No	1	0	7
14	L:L:?1	R:R:R310	4.96	Yes	No	1	0	9
15	L:L:?1	R:R:L312	5.65	Yes	No	0	0	8
16	L:L:?1	R:R:S313	11.24	Yes	No	0	0	9
17	L:L:?1	R:R:S316	3.07	Yes	No	0	0	8
18	R:R:P4	R:R:S3	3.56	No	No	0	6	6
19	R:R:R298	R:R:S3	6.59	No	No	0	1	6
20	R:R:F5	R:R:Y6	12.38	Yes	Yes	1	4	6
21	R:R:F5	R:R:V188	14.42	Yes	No	1	4	3
22	R:R:E190	R:R:F5	4.66	No	Yes	0	1	4
23	R:R:E301	R:R:F5	5.83	Yes	Yes	1	3	4
24	R:R:Q9	R:R:Y6	3.38	No	Yes	1	2	6
25	R:R:V175	R:R:Y6	11.36	No	Yes	1	4	6
26	R:R:Y177	R:R:Y6	9.93	Yes	Yes	1	9	6
27	R:R:Q186	R:R:Y6	5.64	Yes	Yes	1	5	6
28	R:R:V188	R:R:Y6	5.05	No	Yes	1	3	6
29	R:R:E15	R:R:R7	3.49	Yes	Yes	4	3	4
30	R:R:C178	R:R:R7	5.57	No	Yes	4	4	4
31	R:R:R298	R:R:R7	11.73	No	Yes	4	1	4
32	R:R:E302	R:R:R7	15.12	No	Yes	4	3	4
33	R:R:C8	R:R:T11	5.07	No	No	4	9	4
34	R:R:C8	R:R:E15	4.56	No	Yes	4	9	3
35	R:R:C178	R:R:C8	7.28	No	No	4	4	9
36	R:R:N10	R:R:Q9	7.92	No	No	1	6	2
37	R:R:N10	R:R:R94	4.82	No	No	0	6	2
38	R:R:E15	R:R:T11	4.23	Yes	No	4	3	4
39	R:R:S92	R:R:T11	3.2	No	No	0	5	4
40	R:R:T12	R:R:V95	6.35	No	No	0	5	2
41	R:R:N90	R:R:S13	5.96	No	No	0	5	1
42	R:R:T181	R:R:V14	3.17	Yes	No	0	9	4
43	R:R:E15	R:R:P179	3.14	Yes	No	0	3	8
44	R:R:N18	R:R:P179	13.03	No	No	0	3	8
45	R:R:S19	R:R:V21	4.85	No	No	0	6	3
46	R:R:A20	R:R:Y87	6.67	No	No	0	6	8
47	R:R:M22	R:R:R310	11.17	No	No	0	3	9
48	R:R:F27	R:R:L31	12.18	No	No	0	8	6
49	R:R:F27	R:R:S80	11.89	No	No	0	8	8
50	R:R:I317	R:R:T29	6.08	Yes	No	0	9	6
51	R:R:G30	R:R:K76	3.49	No	No	1	9	8
52	R:R:G30	R:R:I317	5.29	No	Yes	1	9	9
53	R:R:D72	R:R:N34	5.39	Yes	No	0	9	9
54	R:R:N34	R:R:P320	13.03	No	No	0	9	9
55	R:R:I325	R:R:L36	4.28	No	No	0	8	5
56	R:R:A37	R:R:I324	6.5	No	Yes	0	9	9
57	R:R:I324	R:R:L41	7.14	Yes	No	0	9	9
58	R:R:A42	R:R:W48	7.78	No	No	0	4	5
59	R:R:R43	R:R:W48	5	No	No	0	5	5
60	R:R:G45	R:R:Y62	4.35	No	Yes	0	6	7
61	R:R:L46	R:R:W48	6.83	No	No	0	4	5
62	R:R:P58	R:R:Y62	5.56	No	Yes	0	6	7
63	R:R:E129	R:R:V60	5.7	No	Yes	5	9	7
64	R:R:V60	R:R:Y140	3.79	Yes	Yes	5	7	8
65	R:R:F61	R:R:V65	5.24	No	No	0	9	8
66	R:R:F61	R:R:R327	4.28	No	No	0	9	9
67	R:R:C66	R:R:Y62	6.72	No	Yes	0	6	7
68	R:R:L64	R:R:M126	5.65	No	No	0	8	9
69	R:R:E129	R:R:L64	5.3	No	No	0	9	8
70	R:R:L64	R:R:V152	4.47	No	No	0	8	5
71	R:R:I324	R:R:V65	3.07	Yes	No	0	9	8
72	R:R:D72	R:R:L68	4.07	Yes	Yes	3	9	9
73	R:R:L68	R:R:Q122	6.65	Yes	No	0	9	7
74	R:R:L123	R:R:L68	4.15	No	Yes	0	8	9
75	R:R:L68	R:R:M126	5.65	Yes	No	0	9	9
76	R:R:D319	R:R:L68	5.43	Yes	Yes	3	9	9
77	R:R:I324	R:R:T69	4.56	Yes	No	0	9	8
78	R:R:Q122	R:R:T71	9.92	No	No	0	7	9
79	R:R:D72	R:R:S316	11.78	Yes	No	0	9	8
80	R:R:D319	R:R:D72	7.98	Yes	Yes	3	9	9
81	R:R:C77	R:R:L73	3.17	No	No	0	6	8
82	R:R:F115	R:R:G75	9.03	Yes	No	0	8	9
83	R:R:I317	R:R:K76	5.82	Yes	No	1	9	8
84	R:R:F108	R:R:L79	7.31	Yes	No	0	6	6
85	R:R:P81	R:R:S80	3.56	No	No	0	8	8
86	R:R:F108	R:R:V82	5.24	Yes	No	0	6	6
87	R:R:T181	R:R:V83	3.17	Yes	No	1	9	9
88	R:R:A85	R:R:L96	3.15	No	No	0	6	4
89	R:R:A86	R:R:T181	3.36	No	Yes	0	6	9
90	R:R:T181	R:R:Y87	11.24	Yes	No	1	9	8
91	R:R:Q89	R:R:R91	11.68	No	No	0	5	3
92	R:R:S92	R:R:V95	3.23	No	No	0	5	2
93	R:R:Q176	R:R:S92	7.22	No	No	0	5	5
94	R:R:F108	R:R:L93	7.31	Yes	No	0	6	6
95	R:R:C183	R:R:L93	4.76	No	No	0	9	6
96	R:R:N102	R:R:R94	7.23	No	No	0	1	2
97	R:R:Q176	R:R:R94	4.67	No	No	0	5	2
98	R:R:L104	R:R:L96	4.15	No	No	0	5	4
99	R:R:D101	R:R:N102	6.73	No	No	0	4	1
100	R:R:C105	R:R:C183	7.28	No	No	0	9	9
101	R:R:F174	R:R:Q106	4.68	Yes	No	0	6	4
102	R:R:F108	R:R:M112	3.73	Yes	Yes	0	6	8
103	R:R:A109	R:R:F174	6.93	No	Yes	0	8	6
104	R:R:F110	R:R:F111	8.57	No	No	0	7	5
105	R:R:F110	R:R:F168	8.57	No	No	0	7	4
106	R:R:F111	R:R:F115	3.22	No	Yes	6	5	8
107	R:R:F184	R:R:M112	4.98	Yes	Yes	1	8	8
108	R:R:L309	R:R:M112	4.24	No	Yes	1	7	8
109	R:R:C164	R:R:S113	5.16	No	No	0	8	7
110	R:R:I185	R:R:S113	3.1	Yes	No	1	7	7
111	R:R:S113	R:R:Y203	3.82	No	Yes	1	7	8
112	R:R:F114	R:R:F115	10.72	Yes	Yes	0	7	8
113	R:R:F114	R:R:S118	6.61	Yes	No	0	7	7
114	R:R:F114	R:R:L161	8.53	Yes	No	0	7	3
115	R:R:L117	R:R:S160	7.51	Yes	No	0	8	7
116	R:R:F163	R:R:L117	3.65	Yes	Yes	1	7	8
117	R:R:C164	R:R:L117	3.17	No	Yes	0	8	8
118	R:R:L117	R:R:Y203	4.69	Yes	Yes	1	8	8
119	R:R:S118	R:R:S160	4.89	No	No	0	7	7
120	R:R:M207	R:R:T120	7.53	No	No	0	7	7
121	R:R:L210	R:R:T120	4.42	No	No	0	6	7
122	R:R:L121	R:R:V156	8.94	No	No	0	5	6
123	R:R:L121	R:R:L210	5.54	No	No	0	5	6
124	R:R:L123	R:R:M270	4.24	No	Yes	0	8	9
125	R:R:L124	R:R:L128	4.15	No	No	0	5	7
126	R:R:A213	R:R:L124	3.15	No	No	0	6	5
127	R:R:L124	R:R:T214	4.42	No	No	0	5	8
128	R:R:F323	R:R:M126	4.98	Yes	No	0	9	9
129	R:R:A127	R:R:N218	4.69	No	No	0	9	9
130	R:R:C217	R:R:L128	3.17	No	No	0	7	7
131	R:R:E129	R:R:Y140	8.98	No	Yes	5	9	8
132	R:R:A221	R:R:C130	3.61	No	No	0	9	9
133	R:R:L132	R:R:W131	5.69	No	Yes	0	5	6
134	R:R:H136	R:R:W131	6.35	No	Yes	0	4	6
135	R:R:L134	R:R:S133	4.5	No	No	0	8	9
136	R:R:S133	R:R:Y140	7.63	No	Yes	0	9	8
137	R:R:L134	R:R:L225	4.15	No	No	0	8	9
138	R:R:G135	R:R:H136	3.18	No	No	0	7	4
139	R:R:G135	R:R:N224	5.09	No	No	0	7	7
140	R:R:F139	R:R:R142	3.21	No	No	7	5	5
141	R:R:F139	R:R:H143	11.31	No	No	7	5	5
142	R:R:I144	R:R:Y140	13.3	No	Yes	0	5	8
143	R:R:H143	R:R:R142	6.77	No	No	7	5	5
144	R:R:F159	R:R:F163	3.22	No	Yes	0	4	7
145	R:R:F163	R:R:Y199	6.19	Yes	Yes	1	7	6
146	R:R:F163	R:R:L202	4.87	Yes	No	0	7	5
147	R:R:F163	R:R:Y203	3.09	Yes	Yes	1	7	8
148	R:R:F163	R:R:L206	4.87	Yes	No	0	7	5
149	R:R:F171	R:R:L166	4.87	No	No	1	4	7
150	R:R:L166	R:R:Y199	5.86	No	Yes	1	7	6
151	R:R:F174	R:R:P167	8.67	Yes	No	0	6	9
152	R:R:P167	R:R:Y199	12.52	No	Yes	0	9	6
153	R:R:F171	R:R:Y199	7.22	No	Yes	1	4	6
154	R:R:K173	R:R:Q186	5.42	No	Yes	1	2	5
155	R:R:K173	R:R:V196	7.59	No	No	1	2	5
156	R:R:F174	R:R:I185	3.77	Yes	Yes	0	6	7
157	R:R:V175	R:R:Y177	5.05	No	Yes	1	4	9
158	R:R:Q186	R:R:V175	5.73	Yes	No	1	5	4
159	R:R:G180	R:R:Q176	4.93	No	No	0	6	5
160	R:R:W182	R:R:Y177	18.33	Yes	Yes	1	9	9
161	R:R:F184	R:R:Y177	5.16	Yes	Yes	1	8	9
162	R:R:M187	R:R:Y177	7.18	No	Yes	0	7	9
163	R:R:D305	R:R:Y177	6.9	No	Yes	0	7	9
164	R:R:C178	R:R:E302	13.67	No	No	4	4	3
165	R:R:P179	R:R:T181	3.5	No	Yes	0	8	9
166	R:R:L306	R:R:W182	5.69	No	Yes	1	7	9
167	R:R:L309	R:R:W182	7.97	No	Yes	1	7	9
168	R:R:F184	R:R:I185	12.56	Yes	Yes	1	8	7
169	R:R:F184	R:R:L309	6.09	Yes	No	1	8	7
170	R:R:I185	R:R:Y199	4.84	Yes	Yes	1	7	6
171	R:R:I185	R:R:Y203	8.46	Yes	Yes	1	7	8
172	R:R:H189	R:R:Q186	3.71	Yes	Yes	1	4	5
173	R:R:Q186	R:R:V196	7.16	Yes	No	1	5	5
174	R:R:M187	R:R:S200	3.07	No	No	0	7	7
175	R:R:A285	R:R:M187	3.22	No	No	0	7	7
176	R:R:V188	R:R:V293	3.21	No	No	0	3	1
177	R:R:E191	R:R:H189	8.62	No	Yes	0	1	4
178	R:R:G192	R:R:H189	3.18	No	Yes	0	1	4
179	R:R:H189	R:R:S193	6.97	Yes	No	0	4	3
180	R:R:H189	R:R:V196	13.84	Yes	No	1	4	5
181	R:R:H189	R:R:L197	3.86	Yes	No	0	4	4
182	R:R:E190	R:R:E191	3.81	No	No	0	1	1
183	R:R:E190	R:R:V293	12.84	No	No	0	1	1
184	R:R:Y199	R:R:Y203	4.96	Yes	Yes	1	6	8
185	R:R:M207	R:R:Y203	7.18	No	Yes	0	7	8
186	R:R:A285	R:R:S204	3.42	No	No	0	7	8
187	R:R:S204	R:R:Y286	6.36	No	Yes	0	8	5
188	R:R:S205	R:R:Y286	5.09	No	Yes	0	4	5
189	R:R:L206	R:R:L210	5.54	No	No	0	5	6
190	R:R:A208	R:R:I282	3.25	No	No	0	6	8
191	R:R:F274	R:R:V211	6.55	Yes	No	3	9	8
192	R:R:S278	R:R:V211	3.23	No	No	3	9	8
193	R:R:F274	R:R:T214	10.38	Yes	No	0	9	8
194	R:R:T271	R:R:V215	3.17	No	No	0	8	6
195	R:R:N218	R:R:T271	5.85	No	No	0	9	8
196	R:R:L264	R:R:M222	8.48	No	Yes	0	7	7
197	R:R:L267	R:R:M222	5.65	No	Yes	0	9	7
198	R:R:L225	R:R:L264	4.15	No	No	0	9	7
199	R:R:R230	R:R:Y226	11.32	No	No	0	5	5
200	R:R:M228	R:R:R231	3.72	No	No	0	8	5
201	R:R:E259	R:R:H229	8.62	No	Yes	2	6	6
202	R:R:E260	R:R:H229	3.69	Yes	Yes	2	9	6
203	R:R:H229	R:R:L261	18	Yes	No	0	6	5
204	R:R:Q233	R:R:R230	9.35	No	No	2	3	5
205	R:R:R230	R:R:R234	10.66	No	No	2	5	3
206	R:R:Q233	R:R:R234	5.84	No	No	2	3	3
207	R:R:I333	R:R:P255	3.39	No	No	0	5	2
208	R:R:D262	R:R:L258	10.86	No	No	2	9	6
209	R:R:H263	R:R:L258	10.29	No	No	2	8	6
210	R:R:L258	R:R:R332	6.07	No	No	0	6	6
211	R:R:E259	R:R:E260	10.15	No	Yes	2	6	9
212	R:R:D262	R:R:H263	5.04	No	No	2	9	8
213	R:R:L266	R:R:R327	6.07	No	No	0	8	9
214	R:R:I322	R:R:L269	4.28	No	No	0	8	5
215	R:R:F274	R:R:M270	3.73	Yes	Yes	3	9	9
216	R:R:D319	R:R:M270	4.16	Yes	Yes	3	9	9
217	R:R:F323	R:R:M270	6.22	Yes	Yes	3	9	9
218	R:R:L273	R:R:V318	4.47	No	No	0	8	8
219	R:R:F274	R:R:S278	5.28	Yes	No	3	9	9
220	R:R:C277	R:R:V314	3.42	No	No	0	9	4
221	R:R:C277	R:R:I315	4.91	No	No	0	9	9
222	R:R:F311	R:R:P280	5.78	No	No	0	6	9
223	R:R:L312	R:R:V281	5.96	No	No	0	8	8
224	R:R:Y283	R:R:Y287	9.93	No	Yes	0	6	4
225	R:R:R284	R:R:Y287	5.14	Yes	Yes	1	5	4
226	R:R:E301	R:R:R284	11.63	Yes	Yes	1	3	5
227	R:R:E304	R:R:R284	17.45	No	Yes	0	1	5
228	R:R:D305	R:R:R284	13.1	No	Yes	0	7	5
229	R:R:F290	R:R:Y286	6.19	No	Yes	0	3	5
230	R:R:K291	R:R:Y287	13.14	No	Yes	0	3	4
231	R:R:K296	R:R:Y287	5.97	No	Yes	1	1	4
232	R:R:E301	R:R:Y287	7.86	Yes	Yes	1	3	4
233	R:R:G288	R:R:K296	3.49	No	No	0	7	1
234	R:R:A289	R:R:F290	5.55	No	No	0	7	3
235	R:R:D292	R:R:K294	12.44	No	No	0	2	1
236	R:R:E301	R:R:K296	6.75	Yes	No	1	3	1
237	R:R:N297	R:R:S300	5.96	No	No	0	3	1
238	R:R:E302	R:R:R298	3.49	No	No	4	3	1
239	R:R:L306	R:R:R310	17.01	No	No	1	7	9
240	R:R:D319	R:R:I315	4.2	Yes	No	0	9	9
241	R:R:D319	R:R:F323	4.78	Yes	Yes	3	9	9
242	R:R:I325	R:R:W321	10.57	No	No	0	8	8
243	R:R:F326	R:R:W321	8.02	No	No	0	5	8
244	R:R:F331	R:R:I325	3.77	No	No	0	7	8
245	R:R:F326	R:R:F331	8.57	No	No	0	5	7
246	R:R:P329	R:R:R332	4.32	No	No	0	7	6
247	R:R:L40	R:R:S328	3	No	No	0	8	7
248	R:R:L74	R:R:V70	2.98	No	No	0	4	5
249	R:R:L104	R:R:V82	2.98	No	No	0	5	6
250	R:R:L219	R:R:V215	2.98	No	No	0	5	6
251	R:R:N90	R:R:V14	2.96	No	No	0	5	4
252	R:R:L38	R:R:T69	2.95	No	No	0	7	8
253	R:R:L279	R:R:T275	2.95	No	No	0	7	5
254	R:R:G172	R:R:Y199	2.9	No	Yes	0	8	6
255	R:R:P98	R:R:R91	2.88	No	No	0	5	3
256	R:R:E301	R:R:S300	2.87	Yes	No	0	3	1
257	R:R:I317	R:R:L26	2.85	Yes	No	0	9	8
258	R:R:I324	R:R:L40	2.85	Yes	No	0	9	8
259	R:R:I144	R:R:L148	2.85	No	No	0	5	5
260	R:R:I322	R:R:L266	2.85	No	No	0	8	8
261	R:R:L219	R:R:M222	2.83	No	Yes	0	5	7
262	R:R:G220	R:R:W131	2.81	No	Yes	0	5	6
263	R:R:L31	R:R:L35	2.77	No	No	0	6	5
264	R:R:L35	R:R:L73	2.77	No	No	0	5	8
265	R:R:L100	R:R:L104	2.77	No	No	0	4	5
266	R:R:E260	R:R:M228	2.71	Yes	No	0	9	8
267	R:R:P320	R:R:W321	2.7	No	No	0	9	8
268	R:R:L96	R:R:Q89	2.66	No	No	0	4	5
269	R:R:E260	R:R:L225	2.65	Yes	No	0	9	9
270	R:R:E260	R:R:L232	2.65	Yes	No	0	9	5
271	R:R:F114	R:R:S157	2.64	Yes	No	0	7	6
272	R:R:F323	R:R:V65	2.62	Yes	No	0	9	8
273	R:R:F290	R:R:V201	2.62	No	No	0	3	4
274	R:R:D262	R:R:E259	2.6	No	No	2	9	6
275	R:R:H229	R:R:Q233	2.47	Yes	No	2	6	3
276	R:R:F115	R:R:L74	2.44	Yes	No	0	8	4
277	R:R:F111	R:R:L78	2.44	No	No	6	5	6
278	R:R:F115	R:R:L78	2.44	Yes	No	6	8	6
279	R:R:L151	R:R:R147	2.43	No	No	0	3	4
280	R:R:I282	R:R:Y286	2.42	No	Yes	0	8	5
281	R:R:L41	R:R:Y62	2.34	No	Yes	0	9	7
282	L:L:?1	R:R:G116	2.33	Yes	No	0	0	8
283	R:R:L128	R:R:W131	2.28	No	Yes	0	7	6
284	R:R:F311	R:R:R307	2.14	No	No	0	6	4
285	R:R:F331	R:R:F335	2.14	No	No	0	7	4
286	R:R:G23	R:R:G24	2.11	No	No	0	8	4
287	R:R:G33	R:R:P320	2.03	No	No	0	9	9
288	R:R:C66	R:R:G67	1.96	No	No	0	6	6
289	R:R:A153	R:R:G67	1.95	No	No	0	7	6
290	R:R:A97	R:R:P98	1.87	No	No	0	1	5
291	R:R:A153	R:R:P154	1.87	No	No	0	7	4
292	R:R:A308	R:R:P280	1.87	No	No	0	7	9
293	R:R:G45	R:R:S44	1.86	No	No	0	6	7
294	R:R:G116	R:R:S119	1.86	No	No	0	8	8
295	R:R:G149	R:R:V60	1.84	No	Yes	0	7	7
296	R:R:G149	R:R:V152	1.84	No	No	0	7	5
297	R:R:G24	R:R:L84	1.71	No	No	0	4	7
298	R:R:G17	R:R:N18	1.7	No	No	0	3	3
299	R:R:A125	R:R:V152	1.7	No	No	0	7	5
300	R:R:A308	R:R:V281	1.7	No	No	0	7	8
301	R:R:L279	R:R:P280	1.64	No	No	0	7	9
302	R:R:S193	R:R:S195	1.63	No	No	0	3	1
303	R:R:S328	R:R:V330	1.62	No	No	0	7	7
304	R:R:A150	R:R:M63	1.61	No	No	0	5	6
305	R:R:A165	R:R:M169	1.61	No	No	0	5	3
306	R:R:A268	R:R:M222	1.61	No	Yes	0	6	7
307	R:R:V21	R:R:V25	1.6	No	No	0	3	4
308	R:R:V314	R:R:V318	1.6	No	No	0	4	8
309	R:R:T29	R:R:V25	1.59	No	No	0	6	4
310	R:R:C130	R:R:L134	1.59	No	No	0	9	8
311	R:R:C130	R:R:L267	1.59	No	No	0	9	9
312	R:R:P257	R:R:Q256	1.58	No	No	0	6	5
313	R:R:H136	R:R:P137	1.53	No	No	0	4	9
314	R:R:M276	R:R:V272	1.52	No	No	0	5	5
315	R:R:F171	R:R:G198	1.51	No	No	0	4	4
316	R:R:G220	R:R:R223	1.5	No	No	0	5	4
317	R:R:L146	R:R:V60	1.49	No	Yes	0	4	7
318	R:R:D101	R:R:S103	1.47	No	No	0	4	3
319	R:R:L148	R:R:T145	1.47	No	No	0	5	6
320	R:R:L146	R:R:M63	1.41	No	No	0	4	6
321	R:R:L166	R:R:M169	1.41	No	No	0	7	3
322	R:R:L212	R:R:L216	1.38	No	No	0	3	4
323	R:R:A227	R:R:R231	1.38	No	No	0	4	5
324	R:R:F61	R:R:S59	1.32	No	No	0	9	7
325	R:R:R147	R:R:T145	1.29	No	No	0	4	6
326	R:R:F139	R:R:L132	1.22	No	No	0	5	5
327	R:R:F138	R:R:R142	1.07	No	No	0	7	5
328	R:R:F334	R:R:F335	1.07	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	6.50133	15	1	0
2	R:R:F5	9.3225	4	1	4
3	R:R:Y6	7.95667	6	1	6
4	R:R:R7	8.9775	4	4	4
5	R:R:E15	3.855	4	4	3
6	R:R:V60	3.205	4	5	7
7	R:R:Y62	4.7425	4	0	7
8	R:R:L68	5.19	5	3	9
9	R:R:D72	7.305	4	3	9
10	R:R:F108	5.8975	4	0	6
11	R:R:M112	4.68	4	1	8
12	R:R:F114	7.125	4	0	7
13	R:R:F115	5.57	5	6	8
14	R:R:L117	4.755	4	1	8
15	R:R:W131	4.2825	4	0	6
16	R:R:Y140	8.425	4	5	8
17	R:R:F163	4.315	6	1	7
18	R:R:F174	6.0125	4	0	6
19	R:R:Y177	8.75833	6	1	9
20	R:R:T181	4.74167	6	1	9
21	R:R:W182	9.355	4	1	9
22	R:R:F184	7.1975	4	1	8
23	R:R:I185	6.546	5	1	7
24	R:R:Q186	5.532	5	1	5
25	R:R:H189	6.69667	6	1	4
26	R:R:Y199	6.35571	7	1	6
27	R:R:Y203	5.36667	6	1	8
28	R:R:M222	4.6425	4	0	7
29	R:R:H229	8.195	4	2	6
30	R:R:E260	4.37	5	2	9
31	R:R:M270	4.5875	4	3	9
32	R:R:F274	6.485	4	3	9
33	R:R:R284	11.83	4	1	5
34	R:R:Y286	5.015	4	0	5
35	R:R:Y287	8.408	5	1	4
36	R:R:E301	6.988	5	1	3
37	R:R:I317	5.01	4	1	9
38	R:R:D319	5.31	5	3	9
39	R:R:F323	4.65	4	3	9
40	R:R:I324	4.824	5	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:Q9	R:R:Y6	12.2092	3.38	No	Yes	1	2	6
2	R:R:Y177	R:R:Y6	30.3035	9.93	Yes	Yes	1	9	6
3	R:R:W182	R:R:Y177	44.457	18.33	Yes	Yes	1	9	9
4	L:L:?1	R:R:W182	44.3483	5.43	Yes	Yes	1	0	9
5	L:L:?1	R:R:K76	10.2367	13.43	Yes	No	1	0	8
6	L:L:?1	R:R:L79	10.6433	3.77	Yes	No	0	0	6
7	R:R:F184	R:R:Y177	18.2795	5.16	Yes	Yes	1	8	9
8	R:R:F184	R:R:M112	42.7985	4.98	Yes	Yes	1	8	8
9	L:L:?1	R:R:T181	23.0094	4.01	Yes	Yes	1	0	9
10	L:L:?1	R:R:L312	10.2367	5.65	Yes	No	0	0	8
11	L:L:?1	R:R:S316	100	3.07	Yes	No	0	0	8
12	R:R:Q186	R:R:Y6	10.3414	5.64	Yes	Yes	1	5	6
13	R:R:E15	R:R:P179	14.4433	3.14	Yes	No	0	3	8
14	R:R:D72	R:R:S316	99.682	11.78	Yes	No	0	9	8
15	R:R:D72	R:R:N34	16.1702	5.39	Yes	No	0	9	9
16	R:R:N34	R:R:P320	14.9585	13.03	No	No	0	9	9
17	R:R:P320	R:R:W321	12.5111	2.7	No	No	0	9	8
18	R:R:D319	R:R:D72	44.2597	7.98	Yes	Yes	3	9	9
19	R:R:D319	R:R:F323	22.9249	4.78	Yes	Yes	3	9	9
20	R:R:F323	R:R:V65	28.0332	2.62	Yes	No	0	9	8
21	R:R:I324	R:R:V65	20.0427	3.07	Yes	No	0	9	8
22	R:R:I324	R:R:L41	11.5772	7.14	Yes	No	0	9	9
23	R:R:L41	R:R:Y62	10.3172	2.34	No	Yes	0	9	7
24	R:R:D72	R:R:L68	50.1731	4.07	Yes	Yes	3	9	9
25	R:R:L68	R:R:M126	49.1386	5.65	Yes	No	0	9	9
26	R:R:L64	R:R:M126	58.9928	5.65	No	No	0	8	9
27	R:R:E129	R:R:L64	55.0318	5.3	No	No	0	9	8
28	R:R:E129	R:R:Y140	49.5693	8.98	No	Yes	5	9	8
29	R:R:F184	R:R:I185	53.3894	12.56	Yes	Yes	1	8	7
30	R:R:I185	R:R:Y203	29.8849	8.46	Yes	Yes	1	7	8
31	R:R:L117	R:R:Y203	16.2145	4.69	Yes	Yes	1	8	8
32	R:R:L117	R:R:S160	15.9568	7.51	Yes	No	0	8	7
33	R:R:S118	R:R:S160	14.7774	4.89	No	No	0	7	7
34	R:R:F114	R:R:S118	13.5899	6.61	Yes	No	0	7	7
35	R:R:F108	R:R:M112	15.7878	3.73	Yes	Yes	0	6	8
36	R:R:F108	R:R:V82	17.7482	5.24	Yes	No	0	6	6
37	R:R:L104	R:R:V82	15.8079	2.98	No	No	0	5	6
38	R:R:L104	R:R:L96	11.9032	4.15	No	No	0	5	4
39	R:R:I185	R:R:Y199	16.6251	4.84	Yes	Yes	1	7	6
40	R:R:D319	R:R:M270	19.0484	4.16	Yes	Yes	3	9	9
41	R:R:F274	R:R:M270	24.8732	3.73	Yes	Yes	3	9	9
42	R:R:F274	R:R:T214	21.3469	10.38	Yes	No	0	9	8
43	R:R:L124	R:R:T214	20.1554	4.42	No	No	0	5	8
44	R:R:L124	R:R:L128	17.7482	4.15	No	No	0	5	7
45	R:R:S133	R:R:Y140	44.7951	7.63	No	Yes	0	9	8
46	R:R:L134	R:R:S133	43.7525	4.5	No	No	0	8	9
47	R:R:L134	R:R:L225	31.0039	4.15	No	No	0	8	9
48	R:R:L225	R:R:L264	10.2528	4.15	No	No	0	9	7
49	R:R:L219	R:R:M222	12.4748	2.83	No	Yes	0	5	7
50	R:R:C130	R:R:L134	12.1085	1.59	No	No	0	9	8
51	R:R:L128	R:R:W131	15.3088	2.28	No	Yes	0	7	6
52	R:R:M187	R:R:Y177	13.3886	7.18	No	Yes	0	7	9
53	R:R:D305	R:R:Y177	13.6261	6.9	No	Yes	0	7	9
54	R:R:H189	R:R:Q186	13.1511	3.71	Yes	Yes	1	4	5
55	R:R:A285	R:R:M187	11.1183	3.22	No	No	0	7	7
56	R:R:E260	R:R:L225	20.9725	2.65	Yes	No	0	9	9
57	R:R:D305	R:R:R284	12.6037	13.1	No	Yes	0	7	5
58	R:R:P179	R:R:T181	17.8367	3.5	No	Yes	0	8	9
59	L:L:?1	R:R:M112	47.0534	5.77	Yes	Yes	1	0	8
60	R:R:V175	R:R:Y177	10.0918	5.05	No	Yes	1	4	9
61	R:R:F323	R:R:M126	11.2431	4.98	Yes	No	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:G23	3.49	1	Yes	No	0	8	0	1
L:L:?1	R:R:K76	13.43	1	Yes	No	0	8	0	1
L:L:?1	R:R:L79	3.77	1	Yes	No	0	6	0	1
L:L:?1	R:R:S80	13.28	1	Yes	No	0	8	0	1
L:L:?1	R:R:V83	10.14	1	Yes	No	0	9	0	1
L:L:?1	R:R:Y87	7.18	1	Yes	No	0	8	0	1
L:L:?1	R:R:M112	5.77	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:T181	4.01	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:W182	5.43	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:L306	3.77	1	Yes	No	0	7	0	1
L:L:?1	R:R:R310	4.96	1	Yes	No	0	9	0	1
L:L:?1	R:R:L312	5.65	1	Yes	No	0	8	0	1
L:L:?1	R:R:S313	11.24	1	Yes	No	0	9	0	1
L:L:?1	R:R:S316	3.07	1	Yes	No	0	8	0	1
R:R:T181	R:R:V14	3.17	1	Yes	No	9	4	1	2
R:R:A20	R:R:Y87	6.67	0	No	No	6	8	2	1
R:R:M22	R:R:R310	11.17	0	No	No	3	9	2	1
R:R:F27	R:R:S80	11.89	0	No	No	8	8	2	1
R:R:G30	R:R:K76	3.49	1	No	No	9	8	2	1
R:R:G30	R:R:I317	5.29	1	No	Yes	9	9	2	2
R:R:D72	R:R:S316	11.78	3	Yes	No	9	8	2	1
R:R:I317	R:R:K76	5.82	1	Yes	No	9	8	2	1
R:R:F108	R:R:L79	7.31	0	Yes	No	6	6	2	1
R:R:P81	R:R:S80	3.56	0	No	No	8	8	2	1
R:R:T181	R:R:V83	3.17	1	Yes	No	9	9	1	1
R:R:A86	R:R:T181	3.36	0	No	Yes	6	9	2	1
R:R:T181	R:R:Y87	11.24	1	Yes	No	9	8	1	1
R:R:F108	R:R:M112	3.73	0	Yes	Yes	6	8	2	1
R:R:F184	R:R:M112	4.98	1	Yes	Yes	8	8	2	1
R:R:L309	R:R:M112	4.24	1	No	Yes	7	8	2	1
R:R:W182	R:R:Y177	18.33	1	Yes	Yes	9	9	1	2
R:R:F184	R:R:Y177	5.16	1	Yes	Yes	8	9	2	2
R:R:P179	R:R:T181	3.5	0	No	Yes	8	9	2	1
R:R:L306	R:R:W182	5.69	1	No	Yes	7	9	1	1
R:R:L309	R:R:W182	7.97	1	No	Yes	7	9	2	1
R:R:F184	R:R:L309	6.09	1	Yes	No	8	7	2	2
R:R:L312	R:R:V281	5.96	0	No	No	8	8	1	2
R:R:L306	R:R:R310	17.01	1	No	No	7	9	1	1
L:L:?1	R:R:G116	2.33	1	Yes	No	0	8	0	1
R:R:G23	R:R:G24	2.11	0	No	No	8	4	1	2
R:R:G116	R:R:S119	1.86	0	No	No	8	8	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9AU0_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.07
Number of Linked Nodes	287
Number of Links	328
Number of Hubs	40
Number of Links mediated by Hubs	160
Number of Communities	7
Number of Nodes involved in Communities	70
Number of Links involved in Communities	97

Path Summary
Number Of Nodes in MetaPath	62
Number Of Links MetaPath	61
Number of Shortest Paths	50435
Length Of Smallest Path	3
Average Path Length	12.5987
Length of Longest Path	30
Minimum Path Strength	1.38
Average Path Strength	6.17322
Maximum Path Strength	18.71
Minimum Path Correlation	0.7
Average Path Correlation	0.921239
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	49.3447
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.3877
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylchitosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q13258
Sequence	>9AU0_nogp_Chain_R S P F Y R C Q N T T S V E K G N S A V M G G V L F S T G L L G N L L A L G L L A R S G L G W P S V F Y M L V C G L T V T D L L G K C L L S P V V L A A Y A Q N R S L R V L A P A L D N S L C Q A F A F F M S F F G L S S T L Q L L A M A L E C W L S L G H P F F Y R R H I T L R L G A L V A P V V S A F S L A F C A L P F M G F G K F V Q Y C P G T W C F I Q M V H E E G S L S V L G Y S V L Y S S L M A L L V L A T V L C N L G A M R N L Y A M H R R L Q R H P Q P L E E L D H L L L L A L M T V L F T M C S L P V I Y R A Y Y G A F K D V K E K N R T S E E A E D L R A L R F L S V I S I V D P W I F I I F R S P V F R I F F H K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9E9S	A	Lipid	Prostanoid	DP₁	Homo sapiens	PGD2	-	Gs/β1/γ1	2.68	2025-09-03	To be published
	9E9S (No Gprot)	A	Lipid	Prostanoid	DP₁	Homo sapiens	PGD2	-		2.68	2025-09-03	To be published
	9EE5	A	Lipid	Prostanoid	DP₁	Homo sapiens	ONO-2550289	-	-	2.89	2025-09-03	doi.org/10.1038/s41467-025-64002-z
	9EI5	A	Lipid	Prostanoid	DP₁	Homo sapiens	-	-	-	2.84	2025-09-03	doi.org/10.1038/s41467-025-64002-z
	9EKH	A	Lipid	Prostanoid	DP₁	Homo sapiens	ONO-3030297	-	-	2.89	2025-09-03	doi.org/10.1038/s41467-025-64002-z
	9UWD	A	Lipid	Prostaglandin	DP₁	Homo sapiens	-	-	-	-	2025-04-09	doi.org/10.1073/pnas.2501902122
	8ZVZ	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-	Gs/β1/γ2	2.35	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZVZ (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-		2.35	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZW0	A	Lipid	Prostaglandin	DP₁	Homo sapiens	PGD2	-	Gs/β1/γ2	2.72	2025-05-28	doi.org/10.1073/pnas.2501902122
	8ZW0 (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	PGD2	-		2.72	2025-05-28	doi.org/10.1073/pnas.2501902122
	9AU0	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-	Gs/β1/γ2	2.45	2025-08-27	To be published
	9AU0 (No Gprot)	A	Lipid	Prostaglandin	DP₁	Homo sapiens	BW245C	-		2.45	2025-08-27	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9AU0_nogp.zip

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