psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D94	5.08	Yes	No	0	0	7
2	L:L:?1	R:R:L115	5.18	Yes	No	1	0	5
3	L:L:?1	R:R:E119	13.88	Yes	Yes	1	0	6
4	L:L:?1	R:R:F173	4.56	Yes	Yes	1	0	5
5	L:L:?1	R:R:P237	3.69	Yes	Yes	0	0	5
6	L:L:?1	R:R:L245	9.32	Yes	No	0	0	4
7	L:L:?1	R:R:F314	9.11	Yes	No	1	0	6
8	L:L:?1	R:R:R318	7.27	Yes	Yes	1	0	7
9	L:L:?1	R:R:Y321	11.4	Yes	No	0	0	5
10	L:L:?1	R:R:N337	12.33	Yes	No	0	0	6
11	L:L:?1	R:R:L341	11.39	Yes	No	0	0	6
12	L:L:?1	R:R:F344	7.29	Yes	Yes	1	0	9
13	R:R:C30	R:R:Q334	7.63	No	No	0	7	5
14	R:R:P32	R:R:S101	5.34	No	No	0	3	5
15	R:R:F33	R:R:L38	3.65	Yes	No	0	6	6
16	R:R:F33	R:R:Q334	14.05	Yes	No	2	6	5
17	R:R:F33	R:R:Y335	13.41	Yes	Yes	2	6	4
18	R:R:F33	R:R:I338	6.28	Yes	No	0	6	6
19	R:R:L35	R:R:V39	4.47	No	No	0	6	8
20	R:R:L38	R:R:W99	15.94	No	No	0	6	6
21	R:R:P40	R:R:V39	5.3	No	No	0	5	8
22	R:R:V39	R:R:W99	3.68	No	No	0	8	6
23	R:R:Q342	R:R:V41	7.16	No	No	0	6	7
24	R:R:L95	R:R:T42	7.37	No	No	0	7	6
25	R:R:T42	R:R:W99	12.13	No	No	0	6	6
26	R:R:C45	R:R:L91	4.76	No	Yes	0	7	8
27	R:R:C45	R:R:L95	4.76	No	No	0	7	7
28	R:R:L346	R:R:L48	4.15	No	No	0	7	6
29	R:R:L48	R:R:S349	6.01	No	No	0	6	8
30	R:R:F49	R:R:V53	6.55	No	No	0	6	7
31	R:R:F49	R:R:L91	9.74	No	Yes	0	6	8
32	R:R:G52	R:R:V51	3.68	No	No	0	8	5
33	R:R:G55	R:R:S54	3.71	No	No	0	9	5
34	R:R:A81	R:R:N56	4.69	No	Yes	0	9	9
35	R:R:D84	R:R:N56	5.39	No	Yes	0	9	9
36	R:R:L85	R:R:N56	6.87	No	Yes	0	7	9
37	R:R:N56	R:R:P352	4.89	Yes	No	0	9	9
38	R:R:L85	R:R:V57	4.47	No	No	0	7	5
39	R:R:V58	R:R:Y362	3.79	No	Yes	0	6	9
40	R:R:I63	R:R:T59	4.56	No	No	0	8	9
41	R:R:N356	R:R:T59	8.77	No	No	3	8	9
42	R:R:T59	R:R:Y362	7.49	No	Yes	3	9	9
43	R:R:L62	R:R:Y362	4.69	No	Yes	0	8	9
44	R:R:L369	R:R:L62	4.15	Yes	No	0	5	8
45	R:R:L369	R:R:R65	9.72	Yes	No	0	5	6
46	R:R:K368	R:R:Y66	10.75	No	No	0	6	5
47	R:R:L369	R:R:Y66	8.21	Yes	No	0	5	5
48	R:R:R67	R:R:R70	7.46	No	No	0	6	8
49	R:R:M69	R:R:N74	11.22	Yes	No	0	8	8
50	R:R:K361	R:R:M69	4.32	No	Yes	0	7	8
51	R:R:M69	R:R:Y362	4.79	Yes	Yes	0	8	9
52	R:R:N74	R:R:T71	4.39	No	No	0	8	8
53	R:R:R152	R:R:T72	3.88	No	No	0	5	7
54	R:R:T72	R:R:V155	7.93	No	No	0	7	7
55	R:R:L75	R:R:R152	4.86	No	No	0	6	5
56	R:R:L132	R:R:Y76	8.21	No	Yes	0	8	8
57	R:R:E135	R:R:Y76	11.22	No	Yes	0	8	8
58	R:R:V155	R:R:Y76	7.57	No	Yes	0	7	8
59	R:R:L158	R:R:Y76	4.69	No	Yes	0	5	8
60	R:R:L132	R:R:L77	4.15	No	Yes	0	8	9
61	R:R:L77	R:R:N356	13.73	Yes	No	0	9	8
62	R:R:H128	R:R:S79	9.76	No	No	0	8	9
63	R:R:I159	R:R:S79	7.74	No	No	0	8	9
64	R:R:M80	R:R:T125	6.02	Yes	No	0	9	9
65	R:R:H128	R:R:M80	5.25	No	Yes	0	8	9
66	R:R:M129	R:R:M80	5.78	No	Yes	4	7	9
67	R:R:M80	R:R:N351	5.61	Yes	No	4	9	9
68	R:R:V82	R:R:W163	3.68	No	Yes	0	7	9
69	R:R:S83	R:R:W163	7.41	No	Yes	0	9	9
70	R:R:A348	R:R:D84	4.63	No	No	0	9	9
71	R:R:D84	R:R:N351	6.73	No	No	0	9	9
72	R:R:C121	R:R:L86	6.35	No	No	0	8	7
73	R:R:I87	R:R:T122	4.56	No	No	1	7	8
74	R:R:F344	R:R:I87	6.28	Yes	No	1	9	7
75	R:R:A348	R:R:L88	4.73	No	No	0	9	6
76	R:R:L91	R:R:Y345	4.69	Yes	Yes	0	8	8
77	R:R:F106	R:R:F93	10.72	Yes	No	0	7	6
78	R:R:F93	R:R:S114	5.28	No	No	0	6	6
79	R:R:D94	R:R:R97	8.34	No	No	0	7	6
80	R:R:D94	R:R:Y345	4.6	No	Yes	0	7	8
81	R:R:R100	R:R:Y96	14.4	No	No	0	5	5
82	R:R:F106	R:R:Y96	10.32	Yes	No	0	7	5
83	R:R:R97	R:R:W104	12	No	No	0	6	8
84	R:R:R97	R:R:S114	3.95	No	No	0	6	6
85	R:R:I338	R:R:L98	4.28	No	No	0	6	6
86	R:R:P103	R:R:S101	5.34	No	No	0	7	5
87	R:R:P103	R:R:R102	4.32	No	No	0	7	6
88	R:R:R102	R:R:R233	9.6	No	No	0	6	4
89	R:R:F106	R:R:W104	21.05	Yes	No	0	7	8
90	R:R:C111	R:R:W104	7.84	No	No	0	9	8
91	R:R:F106	R:R:L110	4.87	Yes	No	0	7	6
92	R:R:G107	R:R:P108	4.06	No	No	0	9	3
93	R:R:L109	R:R:P108	4.93	No	No	0	3	3
94	R:R:E180	R:R:P108	7.86	No	No	0	4	3
95	R:R:C111	R:R:C235	7.28	No	No	0	9	9
96	R:R:R112	R:R:V177	5.23	No	No	0	8	6
97	R:R:F173	R:R:L115	6.09	Yes	No	1	5	5
98	R:R:L115	R:R:V177	8.94	No	No	0	5	6
99	R:R:L167	R:R:Y116	5.86	No	No	0	4	6
100	R:R:A170	R:R:Y116	4	No	No	0	8	6
101	R:R:L174	R:R:Y116	7.03	No	No	0	5	6
102	R:R:E119	R:R:Y123	4.49	Yes	Yes	1	6	7
103	R:R:E119	R:R:F173	12.83	Yes	Yes	1	6	5
104	R:R:E119	R:R:R318	4.65	Yes	Yes	1	6	7
105	R:R:T122	R:R:Y123	4.99	No	Yes	1	8	7
106	R:R:F344	R:R:T122	9.08	Yes	No	1	9	8
107	R:R:S169	R:R:Y123	3.82	No	Yes	1	6	7
108	R:R:T252	R:R:Y123	8.74	No	Yes	1	7	7
109	R:R:Y123	R:R:Y255	15.89	Yes	No	1	7	7
110	R:R:R318	R:R:Y123	5.14	Yes	Yes	1	7	7
111	R:R:A124	R:R:W163	6.48	No	Yes	0	8	9
112	R:R:L126	R:R:W311	14.81	No	Yes	0	7	8
113	R:R:L127	R:R:L162	6.92	No	No	0	7	8
114	R:R:L127	R:R:Y255	8.21	No	No	0	7	7
115	R:R:H128	R:R:W163	5.29	No	Yes	0	8	9
116	R:R:M129	R:R:N351	5.61	No	No	4	7	9
117	R:R:M129	R:R:Y355	7.18	No	No	0	7	9
118	R:R:P259	R:R:T130	5.25	No	No	0	9	7
119	R:R:C262	R:R:T130	5.07	No	No	0	6	7
120	R:R:L263	R:R:S133	4.5	No	No	0	8	9
121	R:R:L266	R:R:S133	6.01	Yes	No	0	7	9
122	R:R:S133	R:R:Y267	10.17	No	No	0	9	8
123	R:R:R136	R:R:Y267	7.2	No	No	0	9	8
124	R:R:C141	R:R:Y137	8.06	No	Yes	0	7	7
125	R:R:R142	R:R:Y137	8.23	Yes	Yes	0	6	7
126	R:R:L266	R:R:Y137	14.07	Yes	Yes	0	7	7
127	R:R:L269	R:R:Y137	8.21	No	Yes	0	5	7
128	R:R:I270	R:R:Y137	3.63	No	Yes	0	8	7
129	R:R:L138	R:R:R142	3.64	No	Yes	0	5	6
130	R:R:I140	R:R:I270	5.89	No	No	0	8	8
131	R:R:R142	R:R:R145	8.53	Yes	No	5	6	6
132	R:R:L144	R:R:R147	3.64	No	No	0	6	6
133	R:R:R154	R:R:V150	13.08	No	No	0	6	6
134	R:R:L158	R:R:L162	6.92	No	No	0	5	8
135	R:R:S169	R:R:Y255	8.9	No	No	1	6	7
136	R:R:G171	R:R:P172	4.06	No	No	0	5	9
137	R:R:M248	R:R:P172	10.06	No	No	0	6	9
138	R:R:F173	R:R:M248	4.98	Yes	No	0	5	6
139	R:R:F175	R:R:L176	6.09	No	No	0	5	5
140	R:R:G178	R:R:V177	3.68	No	No	0	5	6
141	R:R:C235	R:R:E180	7.6	No	No	0	9	4
142	R:R:D182	R:R:R233	14.29	No	No	0	4	4
143	R:R:F231	R:R:L230	4.87	No	No	0	4	2
144	R:R:E234	R:R:R236	17.45	No	No	0	4	5
145	R:R:P237	R:R:Q241	6.32	Yes	No	0	5	4
146	R:R:L242	R:R:P237	4.93	No	Yes	0	3	5
147	R:R:P239	R:R:S238	5.34	No	No	0	7	5
148	R:R:Q241	R:R:S238	7.22	No	No	0	4	5
149	R:R:L245	R:R:L249	9.69	No	No	0	4	5
150	R:R:R246	R:R:W250	6	No	No	0	5	5
151	R:R:I322	R:R:R246	6.26	No	No	6	6	5
152	R:R:N323	R:R:R246	10.85	No	No	6	5	5
153	R:R:I322	R:R:L249	5.71	No	No	0	6	5
154	R:R:T253	R:R:W250	10.92	No	No	0	6	5
155	R:R:I319	R:R:W250	14.09	No	No	0	6	5
156	R:R:R318	R:R:T252	7.76	Yes	No	1	7	7
157	R:R:F257	R:R:T253	3.89	No	No	0	5	6
158	R:R:F256	R:R:F257	8.57	No	No	0	8	5
159	R:R:F256	R:R:L312	7.31	No	No	0	8	6
160	R:R:F256	R:R:H315	9.05	No	No	0	8	8
161	R:R:L258	R:R:P259	6.57	No	No	0	5	9
162	R:R:F260	R:R:S264	7.93	Yes	No	0	7	6
163	R:R:F260	R:R:F307	4.29	Yes	No	0	7	9
164	R:R:F260	R:R:I308	6.28	Yes	No	0	7	7
165	R:R:F307	R:R:L263	4.87	No	No	0	9	8
166	R:R:L300	R:R:Y267	7.03	No	No	0	9	8
167	R:R:G271	R:R:V297	3.68	No	No	0	6	7
168	R:R:E273	R:R:R272	4.65	No	No	0	5	5
169	R:R:L274	R:R:T296	4.42	No	No	0	8	7
170	R:R:E290	R:R:W275	7.63	No	No	0	5	3
171	R:R:V297	R:R:W275	8.58	No	No	0	7	3
172	R:R:E290	R:R:R294	19.77	No	No	0	5	7
173	R:R:Q295	R:R:R298	17.52	No	No	0	8	6
174	R:R:I358	R:R:V299	10.75	No	No	0	7	8
175	R:R:V303	R:R:Y355	8.83	No	No	0	8	9
176	R:R:F307	R:R:W311	8.02	No	Yes	0	9	8
177	R:R:C310	R:R:S347	6.89	No	No	0	9	9
178	R:R:F344	R:R:W311	5.01	Yes	Yes	0	9	8
179	R:R:S347	R:R:W311	7.41	No	Yes	0	9	8
180	R:R:L343	R:R:P313	4.93	No	No	0	8	9
181	R:R:F314	R:R:H315	12.44	No	No	1	6	8
182	R:R:F314	R:R:R318	20.31	No	Yes	1	6	7
183	R:R:H315	R:R:R318	9.03	No	Yes	1	8	7
184	R:R:G317	R:R:V316	3.68	No	No	0	6	6
185	R:R:F336	R:R:V316	6.55	No	No	0	5	6
186	R:R:G317	R:R:I320	5.29	No	No	0	6	6
187	R:R:G317	R:R:N337	5.09	No	No	0	6	6
188	R:R:F332	R:R:I320	8.79	No	No	0	4	6
189	R:R:F336	R:R:I320	3.77	No	No	0	5	6
190	R:R:I322	R:R:N323	4.25	No	No	6	6	5
191	R:R:D326	R:R:S327	4.42	No	No	0	5	5
192	R:R:D326	R:R:M329	4.16	No	No	0	5	3
193	R:R:M329	R:R:R328	7.44	No	No	0	3	4
194	R:R:Y331	R:R:Y335	18.86	No	Yes	0	3	4
195	R:R:Q334	R:R:Y335	6.76	No	Yes	2	5	4
196	R:R:I338	R:R:Q342	4.12	No	No	0	6	6
197	R:R:L341	R:R:Y345	4.69	No	Yes	0	6	8
198	R:R:F344	R:R:Y345	7.22	Yes	Yes	0	9	8
199	R:R:I350	R:R:L346	7.14	No	No	0	7	7
200	R:R:I350	R:R:L354	7.14	No	No	0	7	8
201	R:R:I353	R:R:L357	5.71	No	No	0	8	6
202	R:R:N356	R:R:Y362	12.79	No	Yes	3	8	9
203	R:R:K360	R:R:R363	9.9	No	No	0	4	9
204	R:R:F367	R:R:L371	6.09	No	No	0	4	2
205	R:R:L369	R:R:L370	5.54	Yes	No	0	5	7
206	R:R:L77	R:R:Y355	3.52	Yes	No	0	9	9
207	R:R:E135	R:R:R154	3.49	No	No	0	8	6
208	R:R:G52	R:R:L88	3.42	No	No	0	8	6
209	R:R:L167	R:R:W163	3.42	No	Yes	0	4	9
210	R:R:L176	R:R:P172	3.28	No	No	0	5	9
211	R:R:L312	R:R:P313	3.28	No	No	0	6	9
212	R:R:C121	R:R:I87	3.27	No	No	0	8	7
213	R:R:A365	R:R:M69	3.22	No	Yes	0	7	8
214	R:R:S333	R:R:T324	3.2	No	No	0	7	4
215	R:R:C262	R:R:L266	3.17	No	Yes	0	6	7
216	R:R:A366	R:R:L62	3.15	No	No	0	7	8
217	R:R:A244	R:R:L176	3.15	No	No	0	5	5
218	R:R:C141	R:R:E273	3.04	No	No	0	7	5
219	R:R:M248	R:R:V251	3.04	No	No	0	6	6
220	R:R:M330	R:R:T324	3.01	No	No	0	4	4
221	R:R:L48	R:R:V44	2.98	No	No	0	6	5
222	R:R:L127	R:R:V165	2.98	No	No	0	7	5
223	R:R:L266	R:R:V134	2.98	Yes	No	0	7	7
224	R:R:L138	R:R:V148	2.98	No	No	0	5	6
225	R:R:L274	R:R:V297	2.98	No	No	0	8	7
226	R:R:L354	R:R:V303	2.98	No	No	0	8	8
227	R:R:N337	R:R:S333	2.98	No	No	0	6	7
228	R:R:L77	R:R:T73	2.95	Yes	No	0	9	8
229	R:R:P237	R:R:R236	2.88	Yes	No	0	5	5
230	R:R:Q342	R:R:V339	2.87	No	No	0	6	6
231	R:R:I265	R:R:L261	2.85	No	No	0	4	4
232	R:R:L369	R:R:M61	2.83	Yes	No	0	5	4
233	R:R:P34	R:R:Y335	2.78	No	Yes	0	8	4
234	R:R:F106	R:R:V105	2.62	Yes	No	0	7	5
235	R:R:H293	R:R:L274	2.57	No	No	0	7	8
236	R:R:S359	R:R:Y362	2.54	No	Yes	0	9	9
237	R:R:L357	R:R:R363	2.43	No	No	0	6	9
238	R:R:L357	R:R:Y362	2.34	No	Yes	0	6	9
239	R:R:R153	R:R:R156	2.13	No	No	0	4	4
240	R:R:G55	R:R:P352	2.03	No	No	0	9	9
241	R:R:G90	R:R:P92	2.03	No	No	0	7	9
242	R:R:A81	R:R:G78	1.95	No	No	0	9	7
243	R:R:A170	R:R:G120	1.95	No	No	0	8	5
244	R:R:A340	R:R:P313	1.87	No	No	0	7	9
245	R:R:G118	R:R:V117	1.84	No	No	0	7	6
246	R:R:A124	R:R:A166	1.79	No	No	0	8	8
247	R:R:P32	R:R:S31	1.78	No	No	0	3	7
248	R:R:G271	R:R:I270	1.76	No	No	0	6	8
249	R:R:G36	R:R:L35	1.71	No	No	0	6	6
250	R:R:G243	R:R:L242	1.71	No	No	0	1	3
251	R:R:A81	R:R:V60	1.7	No	No	0	9	7
252	R:R:L91	R:R:P92	1.64	Yes	No	0	8	9
253	R:R:A139	R:R:I140	1.62	No	No	0	8	8
254	R:R:S238	R:R:V179	1.62	No	No	0	5	6
255	R:R:S264	R:R:V304	1.62	No	No	0	6	8
256	R:R:A306	R:R:I350	1.62	No	No	0	7	7
257	R:R:V161	R:R:V165	1.6	No	No	0	4	5
258	R:R:V299	R:R:V303	1.6	No	No	0	8	8
259	R:R:G292	R:R:H293	1.59	No	No	0	6	7
260	R:R:A131	R:R:L162	1.58	No	No	0	8	8
261	R:R:M330	R:R:S327	1.53	No	No	0	4	5
262	R:R:G64	R:R:R70	1.5	No	No	0	4	8
263	R:R:L354	R:R:V302	1.49	No	No	0	8	6
264	R:R:P143	R:R:R142	1.44	No	Yes	5	8	6
265	R:R:P143	R:R:R145	1.44	No	No	5	8	6
266	R:R:E273	R:R:S276	1.44	No	No	0	5	3
267	R:R:Q295	R:R:V299	1.43	No	No	0	8	8
268	R:R:I309	R:R:L343	1.43	No	No	0	6	8
269	R:R:H293	R:R:S277	1.39	No	No	0	7	6
270	R:R:L110	R:R:L113	1.38	No	No	0	6	5
271	R:R:A146	R:R:R142	1.38	No	Yes	0	7	6
272	R:R:R153	R:R:T151	1.29	No	No	0	4	8
273	R:R:R154	R:R:T151	1.29	No	No	0	6	8
274	L:L:?1	R:R:G118	1.28	Yes	No	0	0	7
275	R:R:I63	R:R:R70	1.25	No	No	0	8	8
276	R:R:F260	R:R:L261	1.22	Yes	No	0	7	4
277	R:R:E234	R:R:R102	1.16	No	No	0	4	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	7.82923	13	1	0
2	R:R:F33	9.3475	4	2	6
3	R:R:N56	5.46	4	0	9
4	R:R:M69	5.8875	4	0	8
5	R:R:Y76	7.9225	4	0	8
6	R:R:L77	6.0875	4	0	9
7	R:R:M80	5.665	4	4	9
8	R:R:L91	5.2075	4	0	8
9	R:R:F106	9.916	5	0	7
10	R:R:E119	8.9625	4	1	6
11	R:R:Y123	7.17833	6	1	7
12	R:R:Y137	8.44	5	0	7
13	R:R:R142	4.644	5	5	6
14	R:R:W163	5.256	5	0	9
15	R:R:F173	7.115	4	1	5
16	R:R:P237	4.455	4	0	5
17	R:R:F260	4.93	4	0	7
18	R:R:L266	6.5575	4	0	7
19	R:R:W311	8.8125	4	0	8
20	R:R:R318	9.02667	6	1	7
21	R:R:Y335	10.4525	4	2	4
22	R:R:F344	6.976	5	1	9
23	R:R:Y345	5.3	4	0	8
24	R:R:Y362	5.49	7	3	9
25	R:R:L369	6.09	5	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:P237	30.1684	3.69	Yes	Yes	0	0	5
2	R:R:P237	R:R:R236	17.3978	2.88	Yes	No	0	5	5
3	R:R:E234	R:R:R236	15.5026	17.45	No	No	0	4	5
4	R:R:E234	R:R:R102	13.5979	1.16	No	No	0	4	6
5	L:L:?1	R:R:D94	34.5551	5.08	Yes	No	0	0	7
6	R:R:D94	R:R:Y345	15.5075	4.6	No	Yes	0	7	8
7	R:R:L91	R:R:Y345	46.3588	4.69	Yes	Yes	0	8	8
8	R:R:C45	R:R:L91	37.4363	4.76	No	Yes	0	7	8
9	R:R:C45	R:R:L95	35.6229	4.76	No	No	0	7	7
10	R:R:L95	R:R:T42	33.7999	7.37	No	No	0	7	6
11	R:R:T42	R:R:W99	31.9673	12.13	No	No	0	6	6
12	R:R:L38	R:R:W99	22.6599	15.94	No	No	0	6	6
13	R:R:F33	R:R:L38	20.7696	3.65	Yes	No	0	6	6
14	L:L:?1	R:R:L341	10.8177	11.39	Yes	No	0	0	6
15	L:L:?1	R:R:F344	31.9913	7.29	Yes	Yes	1	0	9
16	R:R:F344	R:R:Y345	31.7605	7.22	Yes	Yes	0	9	8
17	L:L:?1	R:R:E119	28.177	13.88	Yes	Yes	1	0	6
18	R:R:E119	R:R:Y123	33.2516	4.49	Yes	Yes	1	6	7
19	R:R:Y123	R:R:Y255	100	15.89	Yes	No	1	7	7
20	R:R:L127	R:R:Y255	99.7451	8.21	No	No	0	7	7
21	R:R:L127	R:R:L162	97.696	6.92	No	No	0	7	8
22	R:R:L158	R:R:L162	96.2674	6.92	No	No	0	5	8
23	R:R:L158	R:R:Y76	95.4978	4.69	No	Yes	0	5	8
24	R:R:L132	R:R:Y76	86.9649	8.21	No	Yes	0	8	8
25	R:R:L132	R:R:L77	86.1231	4.15	No	Yes	0	8	9
26	R:R:L77	R:R:Y355	59.4132	3.52	Yes	No	0	9	9
27	R:R:V303	R:R:Y355	19.0909	8.83	No	No	0	8	9
28	R:R:L354	R:R:V303	12.025	2.98	No	No	0	8	8
29	L:L:?1	R:R:R318	37.6239	7.27	Yes	Yes	1	0	7
30	R:R:R318	R:R:Y123	33.3478	5.14	Yes	Yes	1	7	7
31	R:R:M129	R:R:Y355	43.2275	7.18	No	No	0	7	9
32	R:R:M129	R:R:N351	20.9909	5.61	No	No	4	7	9
33	R:R:D84	R:R:N351	20.6686	6.73	No	No	0	9	9
34	R:R:D84	R:R:N56	13.5017	5.39	No	Yes	0	9	9
35	R:R:L77	R:R:N356	36.2001	13.73	Yes	No	0	9	8
36	R:R:N356	R:R:Y362	28.1241	12.79	No	Yes	3	8	9
37	R:R:L62	R:R:Y362	11.8519	4.69	No	Yes	0	8	9
38	R:R:M129	R:R:M80	20.9909	5.78	No	Yes	4	7	9
39	R:R:H128	R:R:M80	19.2544	5.25	No	Yes	0	8	9
40	R:R:H128	R:R:W163	14.9543	5.29	No	Yes	0	8	9
41	R:R:F344	R:R:T122	34.2809	9.08	Yes	No	1	9	8
42	R:R:D94	R:R:R97	30.0337	8.34	No	No	0	7	6
43	R:R:R97	R:R:W104	24.6224	12	No	No	0	6	8
44	R:R:F106	R:R:W104	11.6835	21.05	Yes	No	0	7	8
45	R:R:C111	R:R:W104	11.7124	7.84	No	No	0	9	8
46	R:R:F344	R:R:W311	52.8187	5.01	Yes	Yes	0	9	8
47	R:R:F307	R:R:W311	49.0861	8.02	No	Yes	0	9	8
48	R:R:F307	R:R:L263	42.1549	4.87	No	No	0	9	8
49	R:R:L263	R:R:S133	41.241	4.5	No	No	0	8	9
50	R:R:L266	R:R:S133	37.2631	6.01	Yes	No	0	7	9
51	R:R:L266	R:R:Y137	30.683	14.07	Yes	Yes	0	7	7
52	R:R:I270	R:R:Y137	16.8206	3.63	No	Yes	0	8	7
53	R:R:F173	R:R:M248	10.8706	4.98	Yes	No	0	5	6
54	L:L:?1	R:R:L245	11.0919	9.32	Yes	No	0	0	4
55	R:R:F256	R:R:H315	20.2164	9.05	No	No	0	8	8
56	R:R:H315	R:R:R318	14.0933	9.03	No	Yes	1	8	7
57	R:R:F256	R:R:L312	12.2367	7.31	No	No	0	8	6
58	R:R:G271	R:R:I270	13.1746	1.76	No	No	0	6	8
59	R:R:G271	R:R:V297	11.9	3.68	No	No	0	6	7
60	L:L:?1	R:R:N337	26.5657	12.33	Yes	No	0	0	6
61	R:R:G317	R:R:N337	11.6835	5.09	No	No	0	6	6
62	R:R:N337	R:R:S333	13.5979	2.98	No	No	0	6	7
63	R:R:S333	R:R:T324	11.6835	3.2	No	No	0	7	4
64	R:R:T122	R:R:Y123	35.5844	4.99	No	Yes	1	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D94	5.08	1	Yes	No	0	7	0	1
L:L:?1	R:R:L115	5.18	1	Yes	No	0	5	0	1
L:L:?1	R:R:E119	13.88	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:F173	4.56	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:P237	3.69	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L245	9.32	1	Yes	No	0	4	0	1
L:L:?1	R:R:F314	9.11	1	Yes	No	0	6	0	1
L:L:?1	R:R:R318	7.27	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:Y321	11.4	1	Yes	No	0	5	0	1
L:L:?1	R:R:N337	12.33	1	Yes	No	0	6	0	1
L:L:?1	R:R:L341	11.39	1	Yes	No	0	6	0	1
L:L:?1	R:R:F344	7.29	1	Yes	Yes	0	9	0	1
R:R:I87	R:R:T122	4.56	1	No	No	7	8	2	2
R:R:F344	R:R:I87	6.28	1	Yes	No	9	7	1	2
R:R:D94	R:R:R97	8.34	0	No	No	7	6	1	2
R:R:D94	R:R:Y345	4.6	0	No	Yes	7	8	1	2
R:R:F173	R:R:L115	6.09	1	Yes	No	5	5	1	1
R:R:L115	R:R:V177	8.94	1	No	No	5	6	1	2
R:R:E119	R:R:Y123	4.49	1	Yes	Yes	6	7	1	2
R:R:E119	R:R:F173	12.83	1	Yes	Yes	6	5	1	1
R:R:E119	R:R:R318	4.65	1	Yes	Yes	6	7	1	1
R:R:T122	R:R:Y123	4.99	1	No	Yes	8	7	2	2
R:R:F344	R:R:T122	9.08	1	Yes	No	9	8	1	2
R:R:T252	R:R:Y123	8.74	1	No	Yes	7	7	2	2
R:R:R318	R:R:Y123	5.14	1	Yes	Yes	7	7	1	2
R:R:F173	R:R:M248	4.98	1	Yes	No	5	6	1	2
R:R:P237	R:R:Q241	6.32	0	Yes	No	5	4	1	2
R:R:L242	R:R:P237	4.93	0	No	Yes	3	5	2	1
R:R:L245	R:R:L249	9.69	0	No	No	4	5	1	2
R:R:R318	R:R:T252	7.76	1	Yes	No	7	7	1	2
R:R:F344	R:R:W311	5.01	1	Yes	Yes	9	8	1	2
R:R:F314	R:R:H315	12.44	1	No	No	6	8	1	2
R:R:F314	R:R:R318	20.31	1	No	Yes	6	7	1	1
R:R:H315	R:R:R318	9.03	1	No	Yes	8	7	2	1
R:R:G317	R:R:N337	5.09	0	No	No	6	6	2	1
R:R:L341	R:R:Y345	4.69	0	No	Yes	6	8	1	2
R:R:F344	R:R:Y345	7.22	1	Yes	Yes	9	8	1	2
R:R:N337	R:R:S333	2.98	0	No	No	6	7	1	2
R:R:P237	R:R:R236	2.88	0	Yes	No	5	5	1	2
R:R:G118	R:R:V117	1.84	0	No	No	7	6	1	2
L:L:?1	R:R:G118	1.28	1	Yes	No	0	7	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9JMC_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.63
Number of Linked Nodes	261
Number of Links	277
Number of Hubs	25
Number of Links mediated by Hubs	106
Number of Communities	6
Number of Nodes involved in Communities	29
Number of Links involved in Communities	38

Path Summary
Number Of Nodes in MetaPath	65
Number Of Links MetaPath	64
Number of Shortest Paths	44244
Length Of Smallest Path	3
Average Path Length	14.2263
Length of Longest Path	31
Minimum Path Strength	1.29
Average Path Strength	6.94341
Maximum Path Strength	16.525
Minimum Path Correlation	0.7
Average Path Correlation	0.926812
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	48.0147
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	33.0543
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O43193
Sequence	>9JMC_nogp_Chain_R C S P F P L G A L V P V T A V C L C L F V V G V S G N V V T V M L I G R Y R D M R T T T N L Y L G S M A V S D L L I L L G L P F D L Y R L W R S R P W V F G P L L C R L S L Y V G E G C T Y A T L L H M T A L S V E R Y L A I C R P L R A R V L V T R R R V R A L I A V L W A V A L L S A G P F L F L V G V E Q D A A A L F S R E C R P S P A Q L G A L R V M L W V T T A Y F F L P F L C L S I L Y G L I G R E L W S S E R G H R Q T V R V L L V V V L A F I I C W L P F H V G R I I Y I N T E D S R M M Y F S Q Y F N I V A L Q L F Y L S A S I N P I L Y N L I S K K Y R A A A F K L L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8IBU	A	Peptide	Motilin	Motilin	Homo sapiens	Erythromycin-A	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.51	2023-04-12	doi.org/10.1126/sciadv.ade9020
	8IBU (No Gprot)	A	Peptide	Motilin	Motilin	Homo sapiens	Erythromycin-A	-		3.51	2023-04-12	doi.org/10.1126/sciadv.ade9020
	8IBV	A	Peptide	Motilin	Motilin	Homo sapiens	Motilin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.19	2023-04-12	doi.org/10.1126/sciadv.ade9020
	8IBV (No Gprot)	A	Peptide	Motilin	Motilin	Homo sapiens	Motilin	-		3.19	2023-04-12	doi.org/10.1126/sciadv.ade9020
	9JMC	A	Peptide	Motilin	Motilin	Homo sapiens	DS-3801b	-	chim(Gs-CtGq)/β1/γ2	2.57	2025-05-28	doi.org/10.1016/j.celrep.2025.115329
	9JMC (No Gprot)	A	Peptide	Motilin	Motilin	Homo sapiens	DS-3801b	-		2.57	2025-05-28	doi.org/10.1016/j.celrep.2025.115329
	9JMD	A	Peptide	Motilin	Motilin	Homo sapiens	Azithromycin	-	chim(Gs-CtGq)/β1/γ2	2.74	2025-05-28	doi.org/10.1016/j.celrep.2025.115329
	9JMD (No Gprot)	A	Peptide	Motilin	Motilin	Homo sapiens	Azithromycin	-		2.74	2025-05-28	doi.org/10.1016/j.celrep.2025.115329

2D representation of the interactions of this orthosteric/allosteric ligand.

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Data downloads are temporarily suspended for technical reasons. We apologize for the inconvenience.

Data downloads are temporarily suspended for technical reasons.
We apologize for the inconvenience.