psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	L:L:G2	7.32	No	No	0	0	0
2	L:L:?1	R:R:R57	14.3	No	Yes	0	0	5
3	L:L:?1	R:R:G369	7.32	No	No	0	0	3
4	L:L:G2	L:L:P3	4.06	No	No	0	0	0
5	L:L:W14	L:L:W4	21.56	Yes	Yes	0	0	0
6	L:L:W4	R:R:P114	5.4	Yes	No	0	0	5
7	L:L:W4	R:R:N115	15.82	Yes	No	0	0	5
8	L:L:W4	R:R:S368	4.94	Yes	No	0	0	5
9	L:L:L5	R:R:H364	5.14	No	No	0	0	1
10	L:L:L5	R:R:R365	4.86	No	No	0	0	3
11	L:L:E6	L:L:E7	3.81	No	No	3	0	0
12	L:L:E6	R:R:V202	5.7	No	No	0	0	1
13	L:L:E10	L:L:E7	13.95	No	No	0	0	0
14	L:L:E10	L:L:Y12	7.86	No	No	0	0	0
15	L:L:Y12	R:R:V198	8.83	No	No	0	0	1
16	L:L:G13	R:R:R356	4.5	No	Yes	0	0	4
17	L:L:W14	R:R:R356	9	Yes	Yes	0	0	4
18	L:L:W14	R:R:H364	5.29	Yes	No	0	0	1
19	L:L:W14	R:R:I372	8.22	Yes	No	0	0	4
20	L:L:M15	R:R:H207	5.25	No	Yes	0	0	5
21	L:L:?17	L:L:D16	4.4	Yes	Yes	1	0	0
22	L:L:D16	R:R:Y189	11.49	Yes	Yes	1	0	7
23	L:L:D16	R:R:H207	6.3	Yes	Yes	1	0	5
24	L:L:D16	R:R:N353	16.16	Yes	No	0	0	7
25	L:L:D16	R:R:R356	4.76	Yes	Yes	0	0	4
26	L:L:?17	R:R:M134	4.58	Yes	No	0	0	8
27	L:L:?17	R:R:V138	18.11	Yes	No	0	0	7
28	L:L:?17	R:R:L222	5.61	Yes	No	0	0	7
29	L:L:?17	R:R:Y350	7.6	Yes	Yes	0	0	7
30	L:L:?17	R:R:H376	10.42	Yes	Yes	1	0	5
31	L:L:?17	R:R:Y380	4.75	Yes	Yes	1	0	7
32	R:R:L116	R:R:R57	6.07	No	Yes	0	5	5
33	R:R:A370	R:R:R57	4.15	No	Yes	0	3	5
34	R:R:R57	R:R:S373	13.18	Yes	No	0	5	5
35	R:R:L377	R:R:L60	5.54	No	No	0	7	6
36	R:R:M108	R:R:Y61	4.79	Yes	Yes	1	7	7
37	R:R:L112	R:R:Y61	9.38	No	Yes	1	6	7
38	R:R:S373	R:R:Y61	3.82	No	Yes	0	5	7
39	R:R:L377	R:R:Y61	12.89	No	Yes	0	7	7
40	R:R:Y380	R:R:Y61	5.96	Yes	Yes	1	7	7
41	R:R:C384	R:R:I64	8.18	No	No	0	5	7
42	R:R:F65	R:R:V69	9.18	No	No	0	7	6
43	R:R:F65	R:R:M108	6.22	No	Yes	1	7	7
44	R:R:F65	R:R:P109	7.22	No	No	1	7	8
45	R:R:L101	R:R:V69	4.47	Yes	No	0	8	6
46	R:R:A97	R:R:N72	4.69	No	No	0	9	9
47	R:R:L101	R:R:N72	4.12	Yes	No	0	8	9
48	R:R:L101	R:R:M73	5.65	Yes	No	0	8	4
49	R:R:C391	R:R:I75	8.18	No	No	4	7	9
50	R:R:F392	R:R:I75	5.02	Yes	No	0	6	9
51	R:R:F397	R:R:I75	8.79	Yes	No	4	8	9
52	R:R:I76	R:R:L94	4.28	No	No	0	8	7
53	R:R:I76	R:R:L101	4.28	No	Yes	0	8	8
54	R:R:F397	R:R:V78	9.18	Yes	No	0	8	8
55	R:R:L79	R:R:N90	4.12	No	No	0	8	9
56	R:R:L79	R:R:L94	4.15	No	No	0	8	7
57	R:R:L81	R:R:R83	6.07	No	No	0	5	7
58	R:R:R86	R:R:S82	10.54	No	No	0	8	6
59	R:R:E403	R:R:R83	5.82	No	No	0	5	7
60	R:R:R168	R:R:R86	10.66	No	No	0	4	8
61	R:R:N90	R:R:T87	8.77	No	No	0	9	7
62	R:R:Q166	R:R:V88	8.6	Yes	No	0	7	6
63	R:R:R168	R:R:V88	3.92	No	No	0	4	6
64	R:R:A147	R:R:F92	4.16	No	Yes	0	7	8
65	R:R:F92	R:R:I148	3.77	Yes	No	0	8	9
66	R:R:E151	R:R:F92	4.66	No	Yes	0	9	8
67	R:R:A171	R:R:F92	4.16	No	Yes	0	7	8
68	R:R:F92	R:R:V174	6.55	Yes	No	0	8	6
69	R:R:F92	R:R:I175	3.77	Yes	No	0	8	7
70	R:R:L93	R:R:Y390	7.03	No	Yes	0	8	9
71	R:R:C391	R:R:L93	4.76	No	No	0	7	8
72	R:R:I175	R:R:S95	12.39	No	No	0	7	9
73	R:R:S95	R:R:W179	4.94	No	No	0	9	9
74	R:R:D100	R:R:L96	5.43	Yes	No	7	9	9
75	R:R:L96	R:R:S144	7.51	No	No	0	9	8
76	R:R:L96	R:R:N386	4.12	No	No	7	9	9
77	R:R:S99	R:R:V140	6.46	No	No	0	9	8
78	R:R:S141	R:R:S99	4.89	No	No	0	9	9
79	R:R:D100	R:R:S141	5.89	Yes	No	0	9	9
80	R:R:A383	R:R:D100	4.63	No	Yes	0	9	9
81	R:R:D100	R:R:N386	8.08	Yes	No	7	9	9
82	R:R:L102	R:R:L133	8.3	No	No	0	7	5
83	R:R:L102	R:R:S137	7.51	No	No	0	7	7
84	R:R:C107	R:R:L103	4.76	No	No	0	7	7
85	R:R:L103	R:R:S137	7.51	No	No	0	7	7
86	R:R:C107	R:R:M134	6.48	No	No	0	7	8
87	R:R:C107	R:R:Y380	10.75	No	Yes	0	7	7
88	R:R:M108	R:R:P109	5.03	Yes	No	1	7	8
89	R:R:M108	R:R:Y380	7.18	Yes	Yes	1	7	7
90	R:R:F110	R:R:V130	7.87	No	No	0	6	6
91	R:R:L112	R:R:L116	8.3	No	No	1	6	5
92	R:R:L113	R:R:M117	4.24	No	No	0	5	5
93	R:R:F120	R:R:P114	5.78	Yes	No	0	8	5
94	R:R:T119	R:R:V202	4.76	No	No	0	4	1
95	R:R:F120	R:R:F122	5.36	Yes	No	0	8	6
96	R:R:C127	R:R:F120	5.59	No	Yes	2	9	8
97	R:R:C205	R:R:F120	8.38	No	Yes	2	9	8
98	R:R:F122	R:R:I126	7.54	No	No	0	6	5
99	R:R:T124	R:R:V195	6.35	No	Yes	0	4	4
100	R:R:C127	R:R:C205	5.46	No	No	2	9	9
101	R:R:K128	R:R:T193	6.01	No	No	0	7	6
102	R:R:S131	R:R:Y189	5.09	No	Yes	0	5	7
103	R:R:P190	R:R:S131	5.34	No	No	0	6	5
104	R:R:S131	R:R:T193	7.99	No	No	0	5	6
105	R:R:V136	R:R:Y132	6.31	No	No	0	6	6
106	R:R:G183	R:R:Y132	4.35	No	No	0	5	6
107	R:R:P190	R:R:Y132	6.95	No	No	0	6	6
108	R:R:G135	R:R:M186	6.99	No	No	0	6	8
109	R:R:S182	R:R:V136	4.85	No	No	0	8	6
110	R:R:V138	R:R:W346	4.9	No	Yes	0	7	8
111	R:R:L226	R:R:S139	4.5	Yes	No	0	8	8
112	R:R:V140	R:R:W179	28.19	No	No	0	8	9
113	R:R:L226	R:R:T142	4.42	Yes	No	0	8	8
114	R:R:I148	R:R:R152	3.76	No	No	0	9	9
115	R:R:A149	R:R:Y238	5.34	No	Yes	0	9	9
116	R:R:L150	R:R:V233	4.47	No	No	0	6	6
117	R:R:E151	R:R:W165	7.63	No	Yes	5	9	5
118	R:R:E151	R:R:Q166	16.57	No	Yes	5	9	7
119	R:R:R152	R:R:Y238	8.23	No	Yes	0	9	9
120	R:R:R152	R:R:Y390	7.2	No	Yes	0	9	9
121	R:R:C157	R:R:Y153	5.38	No	Yes	0	7	8
122	R:R:R158	R:R:Y153	6.17	Yes	Yes	0	6	8
123	R:R:L240	R:R:Y153	5.86	No	Yes	0	6	8
124	R:R:R158	R:R:S154	3.95	Yes	No	0	6	5
125	R:R:S154	R:R:W165	7.41	No	Yes	0	5	5
126	R:R:I156	R:R:I241	8.83	No	No	0	8	9
127	R:R:Q161	R:R:R158	10.51	No	Yes	0	5	6
128	R:R:Q161	R:R:W165	4.38	No	Yes	0	5	5
129	R:R:V164	R:R:W165	4.9	No	Yes	0	4	5
130	R:R:Q166	R:R:W165	7.67	Yes	Yes	5	7	5
131	R:R:H170	R:R:W165	6.35	No	Yes	0	7	5
132	R:R:R173	R:R:S169	5.27	No	No	0	4	6
133	R:R:H170	R:R:V174	5.54	No	No	0	7	6
134	R:R:H207	R:R:Y189	14.16	Yes	Yes	1	5	7
135	R:R:W218	R:R:Y189	4.82	No	Yes	0	7	7
136	R:R:V191	R:R:Y192	10.09	No	No	0	4	4
137	R:R:P210	R:R:Y192	11.13	No	No	0	4	4
138	R:R:H207	R:R:T193	8.21	Yes	No	0	5	6
139	R:R:R208	R:R:V194	5.23	No	No	0	2	4
140	R:R:P197	R:R:Q196	9.47	No	No	0	1	3
141	R:R:Q196	R:R:R208	5.84	No	No	0	3	2
142	R:R:Q204	R:R:V198	4.3	No	No	0	4	1
143	R:R:G199	R:R:P200	4.06	No	No	0	1	3
144	R:R:Q204	R:R:V202	5.73	No	No	0	4	1
145	R:R:P210	R:R:W209	4.05	No	Yes	0	4	6
146	R:R:R215	R:R:W209	9	No	Yes	0	5	6
147	R:R:W209	R:R:W218	15.93	Yes	No	0	6	7
148	R:R:A212	R:R:R215	4.15	No	No	0	3	5
149	R:R:R215	R:R:R356	4.26	No	Yes	0	5	4
150	R:R:F358	R:R:Q216	10.54	No	No	0	5	4
151	R:R:L221	R:R:L225	5.54	No	No	0	4	5
152	R:R:L222	R:R:L226	5.54	No	Yes	0	7	8
153	R:R:F228	R:R:L223	4.87	No	No	0	5	7
154	R:R:L223	R:R:T354	8.84	No	No	0	7	6
155	R:R:F228	R:R:L224	6.09	No	No	0	5	4
156	R:R:L226	R:R:Y350	5.86	Yes	Yes	0	8	7
157	R:R:F227	R:R:F228	5.36	Yes	No	0	8	5
158	R:R:F227	R:R:F343	7.5	Yes	No	0	8	6
159	R:R:F227	R:R:L347	7.31	Yes	No	0	8	7
160	R:R:F227	R:R:Y350	12.38	Yes	Yes	0	8	7
161	R:R:M234	R:R:V339	6.09	No	No	0	8	8
162	R:R:F342	R:R:M234	6.22	No	No	0	9	8
163	R:R:L335	R:R:Y238	5.86	No	Yes	0	8	9
164	R:R:V339	R:R:Y238	3.79	No	Yes	0	8	9
165	R:R:S242	R:R:V332	6.46	No	No	0	6	7
166	R:R:L335	R:R:S242	4.5	No	No	0	8	6
167	R:R:E244	R:R:R243	6.98	No	No	0	6	5
168	R:R:L247	R:R:R243	4.86	No	No	0	5	5
169	R:R:K328	R:R:L245	5.64	No	No	0	8	8
170	R:R:K329	R:R:Y246	4.78	No	No	0	6	6
171	R:R:V332	R:R:Y246	7.57	No	No	0	7	6
172	R:R:K328	R:R:L326	8.46	No	No	0	8	5
173	R:R:K329	R:R:L326	12.69	No	No	0	6	5
174	R:R:R330	R:R:R333	6.4	No	No	0	8	6
175	R:R:I338	R:R:V389	4.61	No	No	6	8	8
176	R:R:I338	R:R:Y390	6.04	No	Yes	6	8	9
177	R:R:L341	R:R:V385	4.47	No	No	0	6	7
178	R:R:F342	R:R:W346	9.02	No	Yes	0	9	8
179	R:R:W346	R:R:Y350	7.72	Yes	Yes	0	8	7
180	R:R:S379	R:R:W346	11.12	No	Yes	0	7	8
181	R:R:S382	R:R:W346	9.88	No	Yes	0	9	8
182	R:R:I375	R:R:P348	6.77	No	No	0	6	9
183	R:R:H376	R:R:V349	5.54	Yes	No	0	5	7
184	R:R:D359	R:R:W355	7.82	No	No	0	4	5
185	R:R:A366	R:R:W355	3.89	No	No	0	4	5
186	R:R:L367	R:R:W355	5.69	No	No	0	4	5
187	R:R:A363	R:R:D359	4.63	No	No	0	3	4
188	R:R:G360	R:R:P361	4.06	No	No	0	1	1
189	R:R:G362	R:R:R365	7.51	No	No	0	4	3
190	R:R:I372	R:R:I375	4.42	No	No	0	4	6
191	R:R:H376	R:R:I372	5.3	Yes	No	0	5	4
192	R:R:H376	R:R:Y380	7.62	Yes	Yes	1	5	7
193	R:R:S379	R:R:Y380	5.09	No	Yes	0	7	7
194	R:R:V389	R:R:Y390	3.79	No	Yes	6	8	9
195	R:R:C391	R:R:F397	6.98	No	Yes	4	7	8
196	R:R:H394	R:R:R396	7.9	No	No	0	8	7
197	R:R:R395	R:R:R398	9.6	No	No	0	5	9
198	R:R:Q399	R:R:R395	9.35	No	No	0	6	5
199	R:R:T111	R:R:Y380	3.75	No	Yes	0	7	7
200	L:L:A11	R:R:P361	3.74	No	No	0	0	1
201	R:R:V214	R:R:W209	3.68	No	Yes	0	4	6
202	R:R:F374	R:R:L377	3.65	No	No	0	5	7
203	R:R:L240	R:R:R243	3.64	No	No	0	6	5
204	R:R:P188	R:R:V187	3.53	No	No	0	9	4
205	R:R:L145	R:R:Y390	3.52	No	Yes	0	9	9
206	R:R:C345	R:R:S382	3.44	No	No	0	8	9
207	R:R:A104	R:R:S68	3.42	No	No	0	7	8
208	R:R:C127	R:R:V195	3.42	No	Yes	2	9	4
209	R:R:C205	R:R:V195	3.42	No	Yes	2	9	4
210	R:R:A357	R:R:S219	3.42	No	No	0	6	6
211	R:R:I229	R:R:P230	3.39	No	No	0	6	9
212	L:L:W4	R:R:Q204	3.29	Yes	No	0	0	4
213	R:R:L203	R:R:P197	3.28	No	No	0	3	1
214	L:L:E6	R:R:G199	3.27	No	No	3	0	1
215	L:L:E7	R:R:G199	3.27	No	No	3	0	1
216	R:R:R84	R:R:R86	3.2	No	No	0	5	8
217	R:R:C345	R:R:L341	3.17	No	No	0	8	6
218	R:R:A106	R:R:L133	3.15	No	No	0	5	5
219	L:L:E9	R:R:P361	3.14	No	No	0	0	1
220	R:R:T87	R:R:T89	3.14	No	No	0	7	8
221	R:R:I76	R:R:V98	3.07	No	No	0	8	7
222	R:R:M186	R:R:S139	3.07	No	No	0	8	8
223	R:R:I338	R:R:V337	3.07	No	No	0	8	7
224	R:R:F392	R:R:G71	3.01	Yes	No	0	6	8
225	R:R:F343	R:R:G231	3.01	No	No	0	6	6
226	R:R:L143	R:R:S139	3	No	No	0	6	8
227	R:R:L150	R:R:V146	2.98	No	No	0	6	8
228	R:R:L240	R:R:V236	2.98	No	No	0	6	5
229	R:R:L143	R:R:T178	2.95	No	No	0	6	7
230	R:R:I64	R:R:M108	2.92	No	Yes	0	7	7
231	R:R:F110	R:R:P109	2.89	No	No	0	6	8
232	R:R:F392	R:R:P387	2.89	Yes	No	0	6	9
233	R:R:P200	R:R:R201	2.88	No	No	0	3	1
234	R:R:I241	R:R:L335	2.85	No	No	0	9	8
235	R:R:I375	R:R:L367	2.85	No	No	0	6	4
236	R:R:C401	R:R:F397	2.79	No	Yes	0	7	8
237	R:R:A91	R:R:R168	2.77	No	No	0	6	4
238	R:R:F358	R:R:V220	2.62	No	No	0	5	5
239	L:L:W14	R:R:A352	2.59	Yes	No	0	0	5
240	R:R:F358	R:R:T354	2.59	No	No	0	5	6
241	L:L:Y12	R:R:V206	2.52	No	No	0	0	4
242	R:R:F374	R:R:I56	2.51	No	No	0	5	4
243	R:R:F392	R:R:L74	2.44	Yes	No	0	6	7
244	R:R:L402	R:R:R395	2.43	No	No	0	4	5
245	L:L:E9	R:R:R365	2.33	No	No	0	0	3
246	L:L:G2	R:R:G118	2.11	No	No	0	0	4
247	R:R:G70	R:R:G71	2.11	No	No	0	4	8
248	R:R:G369	R:R:P371	2.03	No	No	0	3	5
249	R:R:A381	R:R:C345	1.81	No	No	0	5	8
250	R:R:A149	R:R:A237	1.79	No	No	0	9	6
251	R:R:P348	R:R:S351	1.78	No	No	0	9	6
252	R:R:P230	R:R:V146	1.77	No	No	0	9	8
253	R:R:G248	R:R:L247	1.71	No	No	0	6	5
254	R:R:A104	R:R:V69	1.7	No	No	0	7	6
255	R:R:A400	R:R:V78	1.7	No	No	0	8	8
256	R:R:A235	R:R:V339	1.7	No	No	0	5	8
257	R:R:L113	R:R:P114	1.64	No	No	0	5	5
258	R:R:L378	R:R:P348	1.64	No	No	0	7	9
259	R:R:C384	R:R:M67	1.62	No	No	0	5	4
260	R:R:A155	R:R:I156	1.62	No	No	0	8	8
261	R:R:S211	R:R:V214	1.62	No	No	0	5	4
262	R:R:S169	R:R:T167	1.6	No	No	0	6	8
263	R:R:V187	R:R:V191	1.6	No	No	0	4	4
264	R:R:T404	R:R:V78	1.59	No	No	0	7	8
265	R:R:A400	R:R:L85	1.58	No	No	0	8	8
266	R:R:I126	R:R:V125	1.54	No	No	0	5	3
267	R:R:I229	R:R:V232	1.54	No	No	0	6	4
268	R:R:I58	R:R:T59	1.52	No	No	0	6	3
269	R:R:A162	R:R:Q166	1.52	No	Yes	0	7	7
270	R:R:A357	R:R:Q216	1.52	No	No	0	6	4
271	R:R:M334	R:R:V331	1.52	No	No	0	8	8
272	R:R:F122	R:R:G123	1.51	No	No	0	6	7
273	R:R:L180	R:R:V176	1.49	No	No	0	4	4
274	R:R:L203	R:R:V195	1.49	No	Yes	0	3	4
275	R:R:P159	R:R:R158	1.44	No	Yes	0	9	6
276	R:R:M334	R:R:M393	1.44	No	No	0	8	7
277	R:R:I58	R:R:L112	1.43	No	No	1	6	6
278	R:R:I58	R:R:L116	1.43	No	No	1	6	5
279	R:R:L66	R:R:M67	1.41	No	No	0	5	4
280	R:R:L181	R:R:L185	1.38	No	No	0	5	6
281	R:R:L184	R:R:L185	1.38	No	No	0	4	6
282	R:R:L185	R:R:L221	1.38	No	No	0	6	4
283	R:R:L224	R:R:L225	1.38	No	No	0	4	5
284	R:R:A327	R:R:R330	1.38	No	No	0	7	8
285	R:R:H170	R:R:T167	1.37	No	No	0	7	8
286	R:R:L160	R:R:Q161	1.33	No	No	0	7	5
287	R:R:R213	R:R:S211	1.32	No	No	0	5	5
288	R:R:R330	R:R:V331	1.31	No	No	0	8	8
289	R:R:R213	R:R:T217	1.29	No	No	0	5	5
290	R:R:F392	R:R:L388	1.22	Yes	No	0	6	7
291	R:R:N90	R:R:R396	1.21	No	No	0	9	7
292	R:R:L93	R:R:R396	1.21	No	No	0	8	7
293	R:R:L150	R:R:Y153	1.17	No	Yes	0	6	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:W4	10.202	5	0	0
2	L:L:W14	9.332	5	0	0
3	L:L:D16	8.622	5	1	0
4	L:L:?17	7.92429	7	1	0
5	R:R:R57	9.425	4	0	5
6	R:R:Y61	7.368	5	1	7
7	R:R:F92	4.51167	6	0	8
8	R:R:D100	6.0075	4	7	9
9	R:R:L101	4.63	4	0	8
10	R:R:M108	5.228	5	1	7
11	R:R:F120	6.2775	4	2	8
12	R:R:Y153	4.645	4	0	8
13	R:R:R158	5.5175	4	0	6
14	R:R:W165	6.39	6	5	5
15	R:R:Q166	8.59	4	5	7
16	R:R:Y189	8.89	4	1	7
17	R:R:V195	3.67	4	2	4
18	R:R:H207	8.48	4	1	5
19	R:R:W209	8.165	4	0	6
20	R:R:L226	5.08	4	0	8
21	R:R:F227	8.1375	4	0	8
22	R:R:Y238	5.805	4	0	9
23	R:R:W346	8.528	5	0	8
24	R:R:Y350	8.39	4	0	7
25	R:R:R356	5.63	4	0	4
26	R:R:H376	7.22	4	1	5
27	R:R:Y380	6.44286	7	1	7
28	R:R:Y390	5.516	5	6	9
29	R:R:F392	2.916	5	0	6
30	R:R:F397	6.935	4	4	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:Y380	R:R:Y61	10.2391	5.96	Yes	Yes	1	7	7
2	R:R:H376	R:R:Y380	21.7202	7.62	Yes	Yes	1	5	7
3	R:R:H376	R:R:I372	55.0321	5.3	Yes	No	0	5	4
4	L:L:W14	R:R:I372	47.215	8.22	Yes	No	0	0	4
5	L:L:W14	L:L:W4	62.619	21.56	Yes	Yes	0	0	0
6	L:L:W4	R:R:P114	39.1012	5.4	Yes	No	0	0	5
7	L:L:W14	R:R:H364	13.4182	5.29	Yes	No	0	0	1
8	L:L:L5	R:R:H364	11.8375	5.14	No	No	0	0	1
9	L:L:L5	R:R:R365	10.1594	4.86	No	No	0	0	3
10	L:L:W4	R:R:Q204	20.1616	3.29	Yes	No	0	0	4
11	R:R:Q204	R:R:V202	11.7977	5.73	No	No	0	4	1
12	L:L:?17	L:L:D16	54.9281	4.4	Yes	Yes	1	0	0
13	L:L:D16	R:R:R356	39.6458	4.76	Yes	Yes	0	0	4
14	L:L:D16	R:R:Y189	14.0624	11.49	Yes	Yes	1	0	7
15	L:L:?17	R:R:V138	37.3633	18.11	Yes	No	0	0	7
16	L:L:?17	R:R:Y350	48.6562	7.6	Yes	Yes	0	0	7
17	R:R:C391	R:R:L93	17.0002	4.76	No	No	0	7	8
18	R:R:S379	R:R:Y380	23.6639	5.09	No	Yes	0	7	7
19	R:R:S379	R:R:W346	23.6374	11.12	No	Yes	0	7	8
20	R:R:F342	R:R:W346	100	9.02	No	Yes	0	9	8
21	R:R:F342	R:R:M234	99.2628	6.22	No	No	0	9	8
22	R:R:M234	R:R:V339	98.6385	6.09	No	No	0	8	8
23	R:R:V339	R:R:Y238	97.1308	3.79	No	Yes	0	8	9
24	R:R:R152	R:R:Y238	86.6637	8.23	No	Yes	0	9	9
25	R:R:R152	R:R:Y390	25.5435	7.2	No	Yes	0	9	9
26	R:R:L93	R:R:Y390	20.3299	7.03	No	Yes	0	8	9
27	R:R:I148	R:R:R152	70.6796	3.76	No	No	0	9	9
28	R:R:F92	R:R:I148	69.7675	3.77	Yes	No	0	8	9
29	R:R:E151	R:R:F92	50.7372	4.66	No	Yes	0	9	8
30	R:R:F92	R:R:I175	13.2212	3.77	Yes	No	0	8	7
31	R:R:I175	R:R:S95	12.0412	12.39	No	No	0	7	9
32	R:R:S95	R:R:W179	10.8568	4.94	No	No	0	9	9
33	R:R:F120	R:R:P114	34.4321	5.78	Yes	No	0	8	5
34	R:R:C127	R:R:F120	13.0795	5.59	No	Yes	2	9	8
35	R:R:C205	R:R:F120	13.2256	8.38	No	Yes	2	9	8
36	R:R:C127	R:R:V195	11.5718	3.42	No	Yes	2	9	4
37	R:R:C205	R:R:V195	11.5696	3.42	No	Yes	2	9	4
38	R:R:E151	R:R:W165	41.0582	7.63	No	Yes	5	9	5
39	R:R:S154	R:R:W165	19.4532	7.41	No	Yes	0	5	5
40	R:R:R158	R:R:S154	18.3485	3.95	Yes	No	0	6	5
41	R:R:R158	R:R:Y153	32.1851	6.17	Yes	Yes	0	6	8
42	R:R:L150	R:R:Y153	13.8743	1.17	No	Yes	0	6	8
43	R:R:Q161	R:R:W165	20.6177	4.38	No	Yes	0	5	5
44	R:R:Q161	R:R:R158	18.3905	10.51	No	Yes	0	5	6
45	R:R:L240	R:R:Y153	13.8942	5.86	No	Yes	0	6	8
46	R:R:L335	R:R:Y238	13.106	5.86	No	Yes	0	8	9
47	R:R:R215	R:R:R356	10.3985	4.26	No	Yes	0	5	4
48	R:R:L203	R:R:V195	16.4711	1.49	No	Yes	0	3	4
49	R:R:L203	R:R:P197	13.1282	3.28	No	No	0	3	1
50	R:R:F227	R:R:Y350	13.2544	12.38	Yes	Yes	0	8	7
51	R:R:F227	R:R:F228	10.4206	5.36	Yes	No	0	8	5
52	R:R:I372	R:R:I375	10.1992	4.42	No	No	0	4	6
53	L:L:W14	R:R:R356	31.6383	9	Yes	Yes	0	0	4
54	L:L:?17	R:R:H376	35.0387	10.42	Yes	Yes	1	0	5
55	R:R:M108	R:R:Y380	10.0177	7.18	Yes	Yes	1	7	7
56	R:R:V138	R:R:W346	37.1508	4.9	No	Yes	0	7	8
57	R:R:W346	R:R:Y350	43.799	7.72	Yes	Yes	0	8	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:R57	14.3	0	No	Yes	0	5	0	1
L:L:?1	R:R:G369	7.32	0	No	No	0	3	0	1
L:L:W4	R:R:P114	5.4	0	Yes	No	0	5	0	1
L:L:W4	R:R:N115	15.82	0	Yes	No	0	5	0	1
L:L:W4	R:R:S368	4.94	0	Yes	No	0	5	0	1
L:L:L5	R:R:H364	5.14	0	No	No	0	1	0	1
L:L:L5	R:R:R365	4.86	0	No	No	0	3	0	1
L:L:E6	R:R:V202	5.7	3	No	No	0	1	0	1
L:L:Y12	R:R:V198	8.83	0	No	No	0	1	0	1
L:L:G13	R:R:R356	4.5	0	No	Yes	0	4	0	1
L:L:W14	R:R:R356	9	0	Yes	Yes	0	4	0	1
L:L:W14	R:R:H364	5.29	0	Yes	No	0	1	0	1
L:L:W14	R:R:I372	8.22	0	Yes	No	0	4	0	1
L:L:M15	R:R:H207	5.25	0	No	Yes	0	5	0	1
L:L:D16	R:R:Y189	11.49	1	Yes	Yes	0	7	0	1
L:L:D16	R:R:H207	6.3	1	Yes	Yes	0	5	0	1
L:L:D16	R:R:N353	16.16	1	Yes	No	0	7	0	1
L:L:D16	R:R:R356	4.76	1	Yes	Yes	0	4	0	1
L:L:?17	R:R:M134	4.58	1	Yes	No	0	8	0	1
L:L:?17	R:R:V138	18.11	1	Yes	No	0	7	0	1
L:L:?17	R:R:L222	5.61	1	Yes	No	0	7	0	1
L:L:?17	R:R:Y350	7.6	1	Yes	Yes	0	7	0	1
L:L:?17	R:R:H376	10.42	1	Yes	Yes	0	5	0	1
L:L:?17	R:R:Y380	4.75	1	Yes	Yes	0	7	0	1
R:R:L116	R:R:R57	6.07	1	No	Yes	5	5	2	1
R:R:A370	R:R:R57	4.15	0	No	Yes	3	5	2	1
R:R:R57	R:R:S373	13.18	0	Yes	No	5	5	1	2
R:R:M108	R:R:Y61	4.79	1	Yes	Yes	7	7	2	2
R:R:S373	R:R:Y61	3.82	0	No	Yes	5	7	2	2
R:R:Y380	R:R:Y61	5.96	1	Yes	Yes	7	7	1	2
R:R:C107	R:R:M134	6.48	0	No	No	7	8	2	1
R:R:C107	R:R:Y380	10.75	0	No	Yes	7	7	2	1
R:R:M108	R:R:Y380	7.18	1	Yes	Yes	7	7	2	1
R:R:F120	R:R:P114	5.78	2	Yes	No	8	5	2	1
R:R:T119	R:R:V202	4.76	0	No	No	4	1	2	1
R:R:S131	R:R:Y189	5.09	0	No	Yes	5	7	2	1
R:R:S131	R:R:T193	7.99	0	No	No	5	6	2	2
R:R:V138	R:R:W346	4.9	0	No	Yes	7	8	1	2
R:R:H207	R:R:Y189	14.16	1	Yes	Yes	5	7	1	1
R:R:W218	R:R:Y189	4.82	0	No	Yes	7	7	2	1
R:R:H207	R:R:T193	8.21	1	Yes	No	5	6	1	2
R:R:Q204	R:R:V198	4.3	0	No	No	4	1	1	1
R:R:G199	R:R:P200	4.06	3	No	No	1	3	1	2
R:R:Q204	R:R:V202	5.73	0	No	No	4	1	1	1
R:R:R215	R:R:R356	4.26	0	No	Yes	5	4	2	1
R:R:L222	R:R:L226	5.54	0	No	Yes	7	8	1	2
R:R:L226	R:R:Y350	5.86	0	Yes	Yes	8	7	2	1
R:R:F227	R:R:Y350	12.38	0	Yes	Yes	8	7	2	1
R:R:W346	R:R:Y350	7.72	0	Yes	Yes	8	7	2	1
R:R:S379	R:R:W346	11.12	0	No	Yes	7	8	2	2
R:R:H376	R:R:V349	5.54	1	Yes	No	5	7	1	2
R:R:G360	R:R:P361	4.06	0	No	No	1	1	2	1
R:R:G362	R:R:R365	7.51	0	No	No	4	3	2	1
R:R:I372	R:R:I375	4.42	0	No	No	4	6	1	2
R:R:H376	R:R:I372	5.3	1	Yes	No	5	4	1	1
R:R:H376	R:R:Y380	7.62	1	Yes	Yes	5	7	1	1
R:R:S379	R:R:Y380	5.09	0	No	Yes	7	7	2	1
R:R:T111	R:R:Y380	3.75	0	No	Yes	7	7	2	1
L:L:A11	R:R:P361	3.74	0	No	No	0	1	0	1
L:L:W4	R:R:Q204	3.29	0	Yes	No	0	4	0	1
L:L:E6	R:R:G199	3.27	3	No	No	0	1	0	1
L:L:E7	R:R:G199	3.27	3	No	No	0	1	0	1
L:L:E9	R:R:P361	3.14	0	No	No	0	1	0	1
L:L:W14	R:R:A352	2.59	0	Yes	No	0	5	0	1
L:L:Y12	R:R:V206	2.52	0	No	No	0	4	0	1
L:L:E9	R:R:R365	2.33	0	No	No	0	3	0	1
L:L:G2	R:R:G118	2.11	0	No	No	0	4	0	1
R:R:G369	R:R:P371	2.03	0	No	No	3	5	1	2
R:R:L113	R:R:P114	1.64	0	No	No	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7F8V_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.76
Number of Linked Nodes	274
Number of Links	293
Number of Hubs	30
Number of Links mediated by Hubs	119
Number of Communities	7
Number of Nodes involved in Communities	32
Number of Links involved in Communities	37

Path Summary
Number Of Nodes in MetaPath	58
Number Of Links MetaPath	57
Number of Shortest Paths	73198
Length Of Smallest Path	3
Average Path Length	16.3718
Length of Longest Path	33
Minimum Path Strength	1.305
Average Path Strength	6.68079
Maximum Path Strength	18.69
Minimum Path Correlation	0.7
Average Path Correlation	0.925394
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	40.4167
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.1366
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• enzyme regulator activity • molecular function regulator activity • 1-phosphatidylinositol-3-kinase regulator activity • kinase regulator activity • protein binding • binding • signaling receptor binding • type B gastrin/cholecystokinin receptor binding • G protein-coupled receptor binding • cholecystokinin receptor binding • neuropeptide receptor binding • amide binding • peptide hormone binding • hormone binding • peptide receptor activity • molecular transducer activity • G protein-coupled receptor activity • gastrin receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • neuropeptide receptor activity • cholecystokinin receptor activity • localization • multicellular organismal process • system process • digestion • secretion • transport • digestive system process • acid secretion • gastric acid secretion • establishment of localization • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus
Gene Ontology	Biological Process	• localization • multicellular organismal process • system process • digestion • secretion • transport • digestive system process • acid secretion • gastric acid secretion • establishment of localization • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of biological process • positive regulation of cellular process • cholecystokinin signaling pathway • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • cell surface receptor signaling pathway • developmental process • gland development • animal organ development • anatomical structure development • phospholipase C-activating G protein-coupled receptor signaling pathway • multicellular organism development • digestive system development • tube development • digestive tract development • system development • chemical homeostasis • homeostatic process • regulation of pH • monoatomic ion homeostasis • monoatomic cation homeostasis • pH reduction • cell periphery • cellular anatomical structure • plasma membrane • membrane • membrane-bounded organelle • intracellular organelle • intracellular anatomical structure • organelle • intracellular membrane-bounded organelle • hormone activity • protein binding • binding • molecular function activator activity • signaling receptor binding • molecular function regulator activity • signaling receptor regulator activity • receptor ligand activity • signaling receptor activator activity • response to nutrient levels • response to food • response to chemical • extracellular region • extracellular space • G-protein beta-subunit binding • fibroblast proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • G-protein beta/gamma-subunit complex binding • G protein-coupled receptor binding • cation binding • metal ion binding • positive regulation of neural precursor cell proliferation • neural precursor cell proliferation • regulation of neural precursor cell proliferation • reactive oxygen species metabolic process • regulation of superoxide metabolic process • positive regulation of reactive oxygen species metabolic process • superoxide metabolic process • positive regulation of metabolic process • superoxide anion generation • metabolic process • positive regulation of superoxide anion generation • regulation of superoxide anion generation • regulation of metabolic process • regulation of reactive oxygen species metabolic process • regulation of calcium ion transport • regulation of localization • regulation of transport • regulation of monoatomic ion transport • metal ion transport • calcium ion transport • monoatomic ion transport • regulation of metal ion transport • monoatomic cation transport • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • regulation of signaling • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • regulation of cell communication • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • negative regulation of signaling • negative regulation of biological process • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • negative regulation of cellular process • regulation of G protein-coupled receptor signaling pathway • adenylate cyclase-activating adrenergic receptor signaling pathway • negative regulation of response to stimulus • negative regulation of signal transduction • negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway • regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell division • regulation of body fluid levels • renal system process • positive regulation of urine volume • regulation of urine volume • regulation of vascular associated smooth muscle cell proliferation • positive regulation of vascular associated smooth muscle cell proliferation • regulation of smooth muscle cell proliferation • smooth muscle cell proliferation • positive regulation of smooth muscle cell proliferation • muscle cell proliferation • vascular associated smooth muscle cell proliferation • gamma-aminobutyric acid signaling pathway • purinergic nucleotide receptor signaling pathway • G protein-coupled purinergic receptor signaling pathway • G protein-coupled adenosine receptor signaling pathway • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • regulated exocytosis • regulation of calcium ion-dependent exocytosis • negative regulation of transport • negative regulation of regulated secretory pathway • vesicle-mediated transport • regulation of regulated secretory pathway • secretion by cell • regulation of secretion by cell • negative regulation of secretion • negative regulation of exocytosis • negative regulation of secretion by cell • calcium-ion regulated exocytosis • negative regulation of calcium ion-dependent exocytosis • export from cell • regulation of vesicle-mediated transport • regulation of secretion • exocytosis • regulation of exocytosis • regulation of programmed cell death • negative regulation of apoptotic signaling pathway • negative regulation of programmed cell death • regulation of apoptotic process • cell death • apoptotic signaling pathway • negative regulation of apoptotic process • apoptotic process • programmed cell death • regulation of apoptotic signaling pathway • positive regulation of locomotion • regulation of cell motility • positive regulation of cell migration • regulation of locomotion • positive regulation of cell motility • regulation of cell migration • cell migration • cell motility • locomotion • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • trans-synaptic signaling • modulation of chemical synaptic transmission • negative regulation of synaptic transmission • chemical synaptic transmission • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • response to nutrient • midbody • dense core granule • intracellular vesicle • endomembrane system • cytoplasmic vesicle • secretory granule • secretory vesicle • neuronal dense core vesicle • centrosome • microtubule organizing center • cytoskeleton • membraneless organelle • intracellular membraneless organelle • microtubule cytoskeleton • somatodendritic compartment • dendrite • dendritic tree • nucleus • membrane-enclosed lumen • intracellular organelle lumen • nucleoplasm • organelle lumen • nuclear lumen • neuron to neuron synapse • hippocampal mossy fiber to CA3 synapse • cell body • ciliary basal body
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	PCA
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	PCA
Name	Pidolic acid
Synonyms	L-pyroglutamic acid
Identifier
Formula	C5 H7 N O3
Molecular Weight	129.114
SMILES
PubChem	7405
Formal Charge	0
Total Atoms	16
Total Chiral Atoms	1
Total Bonds	16
Total Aromatic Bonds	0


Code	NFA
PDB Residues	L:L:?17
Environment Details	Open EMBL-EBI Page
Code	NFA
Name	Phenylalanylamide
Synonyms	Phenylalanine amide (S)-2-amino-3-phenylpropanamide Phenylalaninamide L-phenylalanine amide Phenylalanylamide
Identifier
Formula	C9 H12 N2 O
Molecular Weight	164.204
SMILES
PubChem	445694
Formal Charge	0
Total Atoms	24
Total Chiral Atoms	1
Total Bonds	24
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P32239
Sequence	>7F8V_nogp_Chain_R A I R I T L Y A V I F L M S V G G N M L I I V V L G L S R R L R T V T N A F L L S L A V S D L L L A V A C M P F T L L P N L M G T F I F G T V I C K A V S Y L M G V S V S V S T L S L V A I A L E R Y S A I C R P L Q A R V W Q T R S H A A R V I V A T W L L S G L L M V P Y P V Y T V V Q P V G P R V L Q C V H R W P S A R V R Q T W S V L L L L L L F F I P G V V M A V A Y G L I S R E L Y L G L L A K K R V V R M L L V I V V L F F L C W L P V Y S A N T W R A F D G P G A H R A L S G A P I S F I H L L S Y A S A C V N P L V Y C F M H R R F R Q A C L E T C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7XOW	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin	-	chim(NtGi1-Gq)/β1/γ2	3.1	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	7XOW (No Gprot)	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin	-		3.1	2022-07-20	doi.org/10.1038/s41421-022-00420-3
	8IA7	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1L-Gq)/β1/γ2	3.1	2023-12-06	doi.org/10.1038/s41421-022-00420-3
	8IA7 (No Gprot)	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Cholecystokinin-8	-		3.1	2023-12-06	doi.org/10.1038/s41421-022-00420-3
	7F8V	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-	Gi2/β1/γ2	3.3	2021-10-13	doi.org/10.1038/s41589-021-00866-8
	7F8V (No Gprot)	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-		3.3	2021-10-13	doi.org/10.1038/s41589-021-00866-8
	7F8W	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-	chim(NtGsL-Gq)/β1/γ2	3.1	2021-10-13	doi.org/10.1038/s41589-021-00866-8
	7F8W (No Gprot)	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-		3.1	2021-10-13	doi.org/10.1038/s41589-021-00866-8

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