psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:E54	R:R:K51	5.4	No	No	0	7	4
2	R:R:E52	R:R:W55	5.45	No	No	0	3	4
3	R:R:E54	R:R:Y53	4.49	No	No	0	7	4
4	R:R:E54	R:R:L57	3.98	No	No	0	7	5
5	R:R:L57	R:R:Y61	7.03	No	Yes	1	5	7
6	R:R:L57	R:R:T347	7.37	No	No	1	5	4
7	R:R:G60	R:R:I63	3.53	No	No	0	4	3
8	R:R:L108	R:R:Y61	7.03	Yes	Yes	1	7	7
9	R:R:L112	R:R:Y61	12.89	No	Yes	0	6	7
10	R:R:T347	R:R:Y61	3.75	No	Yes	1	4	7
11	R:R:W351	R:R:Y61	9.65	No	Yes	0	5	7
12	R:R:Y354	R:R:Y61	4.96	Yes	Yes	1	7	7
13	R:R:V64	R:R:W351	6.13	No	No	0	7	5
14	R:R:F65	R:R:L69	3.65	No	Yes	0	6	6
15	R:R:F65	R:R:L108	8.53	No	Yes	0	6	7
16	R:R:A68	R:R:T104	3.36	No	No	0	8	7
17	R:R:I105	R:R:L69	4.28	No	Yes	0	4	6
18	R:R:N72	R:R:S97	8.94	No	No	0	9	9
19	R:R:D100	R:R:N72	6.73	Yes	No	0	9	9
20	R:R:N72	R:R:P361	9.77	No	No	0	9	9
21	R:R:S97	R:R:V75	3.23	No	No	0	9	9
22	R:R:N365	R:R:V75	5.91	No	No	0	7	9
23	R:R:V79	R:R:V94	4.81	No	No	0	7	6
24	R:R:A378	R:R:K81	3.21	No	No	0	6	6
25	R:R:H84	R:R:N82	3.83	No	Yes	0	5	6
26	R:R:M85	R:R:N82	5.61	Yes	Yes	0	8	6
27	R:R:A378	R:R:N82	3.13	No	Yes	0	6	6
28	R:R:H83	R:R:R86	20.31	No	No	0	7	8
29	R:R:F371	R:R:M85	4.98	Yes	Yes	0	8	8
30	R:R:E374	R:R:M85	5.41	No	Yes	0	7	8
31	R:R:S164	R:R:V88	3.23	No	No	0	5	6
32	R:R:I93	R:R:N90	5.66	No	No	0	8	9
33	R:R:C147	R:R:F92	5.59	No	Yes	0	6	8
34	R:R:F92	R:R:I148	3.77	Yes	No	0	8	8
35	R:R:I93	R:R:N365	9.91	No	No	0	8	7
36	R:R:N95	R:R:T144	5.85	No	No	0	9	7
37	R:R:I173	R:R:N95	7.08	No	No	0	8	9
38	R:R:N95	R:R:W177	5.65	No	No	0	9	9
39	R:R:D100	R:R:L96	5.43	Yes	No	0	9	9
40	R:R:L96	R:R:T144	4.42	No	No	0	9	7
41	R:R:L145	R:R:L96	5.54	No	No	0	9	9
42	R:R:A99	R:R:V140	3.39	No	No	0	8	7
43	R:R:D100	R:R:S357	5.89	Yes	No	0	9	9
44	R:R:D100	R:R:N360	10.77	Yes	No	0	9	9
45	R:R:L102	R:R:S137	6.01	No	No	0	6	5
46	R:R:C107	R:R:V103	5.12	Yes	No	0	7	7
47	R:R:S357	R:R:V103	6.46	No	No	0	9	7
48	R:R:C107	R:R:Q134	9.16	Yes	No	0	7	7
49	R:R:C107	R:R:Y354	4.03	Yes	Yes	0	7	7
50	R:R:L108	R:R:P109	3.28	Yes	No	0	7	8
51	R:R:L108	R:R:Y354	12.89	Yes	Yes	1	7	7
52	R:R:D115	R:R:T111	5.78	Yes	No	1	5	7
53	R:R:H350	R:R:T111	5.48	Yes	No	1	5	7
54	R:R:T111	R:R:Y354	4.99	No	Yes	1	7	7
55	R:R:T117	R:R:V113	3.17	No	No	0	5	4
56	R:R:D115	R:R:T347	8.67	Yes	No	1	5	4
57	R:R:D115	R:R:H350	5.04	Yes	Yes	1	5	5
58	R:R:T117	R:R:T119	10.99	No	No	0	5	5
59	R:R:E118	R:R:R339	6.98	No	No	0	4	1
60	R:R:E118	R:R:Y343	4.49	No	No	0	4	3
61	R:R:F121	R:R:T119	3.89	No	No	0	4	5
62	R:R:F207	R:R:T119	10.38	No	No	0	3	5
63	R:R:F122	R:R:W120	15.03	No	Yes	0	6	7
64	R:R:C127	R:R:W120	7.84	No	Yes	3	9	7
65	R:R:C193	R:R:W120	3.92	No	Yes	3	4	7
66	R:R:C210	R:R:W120	18.28	No	Yes	3	9	7
67	L:L:L7	R:R:W120	3.42	No	Yes	0	0	7
68	R:R:F122	R:R:L126	6.09	No	No	0	6	5
69	R:R:C127	R:R:C193	3.64	No	No	3	9	4
70	R:R:C127	R:R:C210	7.28	No	No	3	9	9
71	R:R:I130	R:R:P131	3.39	Yes	No	0	5	5
72	R:R:I130	R:R:Q134	4.12	Yes	No	0	5	7
73	R:R:M191	R:R:P131	5.03	No	No	0	6	5
74	R:R:V136	R:R:Y132	7.57	No	No	0	5	6
75	R:R:A188	R:R:Y132	4	No	No	0	6	6
76	L:L:L7	R:R:Q134	6.65	No	No	0	0	7
77	R:R:M184	R:R:T135	9.03	Yes	No	0	7	6
78	R:R:Q187	R:R:T135	7.09	Yes	No	0	6	6
79	L:L:M9	R:R:V138	7.61	No	No	0	0	6
80	R:R:S139	R:R:S180	3.26	No	No	0	7	8
81	R:R:V140	R:R:W177	12.26	No	No	0	7	9
82	R:R:S180	R:R:V140	3.23	No	No	0	8	7
83	R:R:P235	R:R:V142	3.53	No	No	0	9	8
84	R:R:F313	R:R:V142	3.93	Yes	No	4	9	8
85	R:R:V142	R:R:Y317	5.05	No	No	4	8	7
86	R:R:I176	R:R:L143	4.28	No	No	0	6	6
87	R:R:F313	R:R:L145	3.65	Yes	No	0	9	9
88	R:R:L145	R:R:Y364	8.21	No	Yes	0	9	9
89	R:R:P235	R:R:S146	3.56	No	No	0	9	7
90	R:R:C147	R:R:I176	4.91	No	No	0	6	6
91	R:R:I148	R:R:R152	5.01	No	No	0	8	9
92	R:R:I148	R:R:Y364	6.04	No	Yes	0	8	9
93	R:R:A149	R:R:Y243	6.67	No	Yes	0	8	9
94	R:R:D151	R:R:S164	7.36	No	No	0	9	5
95	R:R:R152	R:R:Y243	6.17	No	Yes	0	9	9
96	R:R:W153	R:R:Y154	6.75	Yes	No	0	8	4
97	R:R:C157	R:R:W153	7.84	No	Yes	0	7	8
98	R:R:H158	R:R:W153	7.41	No	Yes	0	6	8
99	R:R:A242	R:R:W153	3.89	No	Yes	0	5	8
100	R:R:Q245	R:R:W153	10.95	No	Yes	0	5	8
101	R:R:K163	R:R:Y154	10.75	No	No	6	5	4
102	R:R:R168	R:R:Y154	6.17	No	No	6	7	4
103	R:R:I156	R:R:I246	8.83	No	No	7	8	9
104	R:R:C157	R:R:I246	3.27	No	No	0	7	9
105	R:R:H158	R:R:M161	7.88	No	No	0	6	5
106	R:R:L160	R:R:P159	3.28	No	No	0	7	9
107	R:R:K163	R:R:M161	4.32	No	No	0	5	5
108	R:R:K163	R:R:R168	7.43	No	No	6	5	7
109	R:R:K167	R:R:N171	6.99	No	No	0	5	3
110	R:R:N171	R:R:R170	4.82	No	No	0	3	4
111	R:R:I183	R:R:M184	4.37	No	Yes	0	5	7
112	R:R:F227	R:R:M184	4.98	No	Yes	0	5	7
113	R:R:I185	R:R:P186	3.39	No	No	0	5	6
114	R:R:P186	R:R:Y223	19.47	No	Yes	0	6	8
115	R:R:M191	R:R:Q187	4.08	No	Yes	2	6	6
116	R:R:E212	R:R:Q187	3.82	Yes	Yes	2	4	6
117	L:L:T8	R:R:Q187	4.25	No	Yes	0	0	6
118	R:R:E212	R:R:V190	7.13	Yes	No	2	4	6
119	R:R:V190	R:R:W214	9.81	No	Yes	2	6	4
120	R:R:E212	R:R:M191	4.06	Yes	No	2	4	6
121	R:R:E192	R:R:R213	23.26	No	No	0	5	4
122	R:R:T195	R:R:T208	7.85	No	No	0	2	3
123	R:R:F207	R:R:T208	7.78	No	No	0	3	3
124	L:L:G5	R:R:V209	3.68	No	No	0	0	5
125	R:R:D211	R:R:R328	9.53	No	No	0	5	4
126	L:L:G5	R:R:D211	5.03	No	No	0	0	5
127	R:R:E212	R:R:W214	14.17	Yes	Yes	2	4	4
128	R:R:E212	R:R:H224	8.62	Yes	No	0	4	6
129	R:R:P220	R:R:W214	25.67	No	Yes	0	5	4
130	R:R:W214	R:R:Y223	6.75	Yes	Yes	0	4	8
131	R:R:H224	R:R:Y223	5.44	No	Yes	0	6	8
132	R:R:H224	R:R:R328	11.28	No	No	0	6	4
133	R:R:F227	R:R:T231	7.78	No	No	0	5	6
134	L:L:M9	R:R:F227	3.73	No	No	0	0	5
135	R:R:F228	R:R:Y232	7.22	No	Yes	0	6	8
136	R:R:F228	R:R:V325	3.93	No	No	0	6	6
137	R:R:L236	R:R:Y232	4.69	No	Yes	0	6	8
138	R:R:L318	R:R:Y232	4.69	No	Yes	0	6	8
139	R:R:S321	R:R:Y232	7.63	No	Yes	0	6	8
140	R:R:C237	R:R:M233	3.24	No	No	0	4	5
141	R:R:M239	R:R:Y243	3.59	No	Yes	0	8	9
142	R:R:F313	R:R:M239	8.71	Yes	No	0	9	8
143	R:R:L306	R:R:Y243	8.21	No	Yes	0	8	9
144	R:R:F247	R:R:W251	15.03	No	No	0	6	5
145	R:R:A303	R:R:F247	4.16	No	No	0	7	6
146	R:R:F247	R:R:M307	6.22	No	No	0	6	6
147	R:R:R300	R:R:W251	19.99	No	No	0	5	5
148	R:R:Q295	R:R:R299	3.5	No	No	0	4	8
149	R:R:K301	R:R:R304	13.61	No	No	0	8	8
150	R:R:I363	R:R:V309	4.61	Yes	No	5	8	8
151	R:R:V309	R:R:Y364	5.05	No	Yes	5	8	9
152	R:R:F313	R:R:Y317	6.19	Yes	No	4	9	7
153	R:R:C316	R:R:N356	6.3	No	No	0	8	9
154	R:R:N356	R:R:Y317	9.3	No	No	0	9	7
155	R:R:L318	R:R:P319	4.93	No	No	0	6	9
156	R:R:P319	R:R:S349	3.56	No	No	0	9	6
157	R:R:L352	R:R:P319	3.28	No	No	0	8	9
158	R:R:I320	R:R:S349	3.1	No	No	0	7	6
159	R:R:H350	R:R:I320	5.3	Yes	No	0	5	7
160	R:R:I320	R:R:V353	4.61	No	No	0	7	7
161	R:R:F346	R:R:L323	9.74	Yes	No	0	4	5
162	L:L:T8	R:R:N324	8.77	No	No	0	0	7
163	R:R:K327	R:R:R328	18.56	No	No	0	3	4
164	R:R:F333	R:R:K327	3.72	Yes	No	0	4	3
165	R:R:F346	R:R:K327	3.72	Yes	No	0	4	3
166	R:R:F330	R:R:V329	3.93	No	No	0	3	5
167	R:R:F333	R:R:V342	11.8	Yes	No	0	4	5
168	R:R:A334	R:R:H335	4.39	No	No	0	2	1
169	R:R:D338	R:R:T336	4.34	No	No	0	3	4
170	L:L:H2	R:R:T336	6.85	No	No	0	0	4
171	R:R:D338	R:R:T341	5.78	No	No	0	3	4
172	L:L:H2	R:R:R339	18.05	No	No	0	0	1
173	R:R:E340	R:R:T341	4.23	No	No	0	1	4
174	L:L:I6	R:R:Y343	4.84	No	No	0	0	3
175	R:R:F346	R:R:H350	5.66	Yes	Yes	0	4	5
176	L:L:I6	R:R:F346	7.54	No	Yes	0	0	4
177	R:R:F348	R:R:L352	4.87	No	No	0	4	8
178	R:R:A355	R:R:W351	5.19	No	No	0	4	5
179	R:R:V353	R:R:Y354	3.79	No	Yes	0	7	7
180	R:R:N356	R:R:N360	9.54	No	No	0	9	9
181	R:R:I363	R:R:Y364	4.84	Yes	Yes	5	8	9
182	R:R:F371	R:R:N365	6.04	Yes	No	0	8	7
183	R:R:F366	R:R:F371	5.36	No	Yes	0	5	8
184	R:R:E374	R:R:K370	17.55	No	No	0	7	7
185	R:R:I189	R:R:V190	3.07	No	No	0	5	6
186	R:R:I363	R:R:V312	3.07	Yes	No	0	8	6
187	R:R:I116	R:R:T117	3.04	No	No	0	5	5
188	R:R:M184	R:R:V136	3.04	Yes	No	0	7	5
189	R:R:L126	R:R:S125	3	No	No	0	5	3
190	R:R:L238	R:R:S146	3	No	No	0	7	7
191	R:R:G369	R:R:R372	3	No	No	0	5	8
192	R:R:L69	R:R:V101	2.98	Yes	No	0	6	7
193	R:R:L310	R:R:V240	2.98	No	No	0	8	5
194	R:R:L69	R:R:T104	2.95	Yes	No	0	6	7
195	R:R:L250	R:R:T302	2.95	Yes	No	0	8	8
196	R:R:L306	R:R:T302	2.95	No	No	0	8	8
197	R:R:D115	R:R:V114	2.92	Yes	No	0	5	5
198	R:R:I70	R:R:L74	2.85	No	No	0	4	6
199	R:R:I116	R:R:L112	2.85	No	No	0	5	6
200	R:R:I156	R:R:L250	2.85	No	Yes	7	8	8
201	R:R:I246	R:R:L250	2.85	No	Yes	7	9	8
202	R:R:I322	R:R:L318	2.85	No	No	0	5	6
203	R:R:I362	R:R:L367	2.85	No	No	0	6	7
204	R:R:L229	R:R:M233	2.83	No	No	0	4	5
205	R:R:L310	R:R:M239	2.83	No	No	0	8	8
206	R:R:L367	R:R:M305	2.83	No	No	0	7	8
207	R:R:L310	R:R:M307	2.83	No	No	0	8	6
208	R:R:K249	R:R:L250	2.82	No	Yes	0	5	8
209	R:R:A78	R:R:F375	2.77	No	No	0	8	7
210	R:R:A169	R:R:F92	2.77	No	Yes	0	7	8
211	L:L:A3	R:R:F333	2.77	No	Yes	0	0	4
212	R:R:C181	R:R:Y132	2.69	No	No	0	4	6
213	R:R:A169	R:R:Y91	2.67	No	No	0	7	4
214	R:R:F92	R:R:S172	2.64	Yes	No	0	8	6
215	R:R:I296	R:R:R300	2.51	No	No	0	4	5
216	R:R:F228	R:R:M233	2.49	No	No	0	6	5
217	R:R:F333	R:R:M332	2.49	Yes	No	0	4	3
218	R:R:V77	R:R:W80	2.45	No	No	0	5	3
219	R:R:F375	R:R:L74	2.44	No	No	0	7	6
220	R:R:T341	R:R:W345	2.43	No	No	0	4	5
221	R:R:R297	R:R:R300	2.13	No	No	0	5	5
222	R:R:G215	R:R:G216	2.11	No	No	0	4	5
223	R:R:A59	R:R:G60	1.95	No	No	0	4	4
224	R:R:W214	R:R:Y219	1.93	Yes	No	0	4	3
225	R:R:A234	R:R:P235	1.87	No	No	0	5	9
226	R:R:A358	R:R:A68	1.79	No	No	0	5	8
227	R:R:G71	R:R:I70	1.76	No	No	0	8	4
228	R:R:C76	R:R:S97	1.72	No	No	0	6	9
229	R:R:A99	R:R:S141	1.71	No	No	0	8	9
230	R:R:A166	R:R:V88	1.7	No	No	0	3	6
231	L:L:A4	R:R:V209	1.7	No	No	0	0	5
232	R:R:C107	R:R:T106	1.69	Yes	No	0	7	5
233	R:R:E217	R:R:G216	1.64	No	No	0	3	5
234	R:R:S137	R:R:V103	1.62	No	No	0	5	7
235	R:R:A110	R:R:I130	1.62	No	Yes	0	4	5
236	R:R:S194	R:R:V196	1.62	No	No	0	3	3
237	R:R:S194	R:R:V209	1.62	No	No	0	3	5
238	R:R:A78	R:R:M85	1.61	No	Yes	0	8	8
239	R:R:A298	R:R:K294	1.61	No	No	0	6	3
240	R:R:V101	R:R:V73	1.6	No	No	0	7	4
241	R:R:V308	R:R:V312	1.6	No	No	0	6	6
242	R:R:V325	R:R:V329	1.6	No	No	0	6	5
243	R:R:C76	R:R:L98	1.59	No	No	0	6	5
244	R:R:T89	R:R:V88	1.59	No	No	0	8	6
245	R:R:A314	R:R:L236	1.58	No	No	0	5	6
246	R:R:A377	R:R:N82	1.56	No	Yes	0	4	6
247	L:L:N1	R:R:A334	1.56	No	No	0	0	2
248	L:L:A4	L:L:N1	1.56	No	No	0	0	0
249	R:R:I63	R:R:V64	1.54	No	No	0	3	7
250	R:R:I130	R:R:V129	1.54	Yes	No	0	5	4
251	R:R:I178	R:R:V174	1.54	No	No	0	3	3
252	R:R:I175	R:R:V179	1.54	No	No	0	3	5
253	R:R:H49	R:R:P50	1.53	No	No	0	4	5
254	R:R:H158	R:R:P159	1.53	No	No	0	6	9
255	R:R:M85	R:R:V79	1.52	Yes	No	0	8	7
256	R:R:K221	R:R:V329	1.52	No	No	0	4	5
257	R:R:L74	R:R:V77	1.49	No	No	0	6	5
258	R:R:L133	R:R:T106	1.47	No	No	0	5	5
259	R:R:I178	R:R:I182	1.47	No	No	0	3	3
260	R:R:I362	R:R:I363	1.47	No	Yes	0	6	8
261	R:R:N90	R:R:T87	1.46	No	No	0	9	7
262	R:R:I225	R:R:M222	1.46	No	No	0	5	4
263	R:R:G123	R:R:W120	1.41	No	Yes	0	8	7
264	R:R:G215	R:R:W214	1.41	No	Yes	0	4	4
265	R:R:L244	R:R:M307	1.41	No	No	0	2	6
266	R:R:L150	R:R:L238	1.38	No	No	0	6	7
267	R:R:E217	R:R:I218	1.37	No	No	0	3	4
268	R:R:E292	R:R:I293	1.37	No	No	0	3	2
269	R:R:C226	R:R:Y223	1.34	No	Yes	0	4	8
270	R:R:A166	R:R:Y91	1.33	No	No	0	3	4
271	R:R:F371	R:R:S368	1.32	Yes	No	0	8	8
272	R:R:F65	R:R:V66	1.31	No	No	0	6	4
273	R:R:R168	R:R:T165	1.29	No	No	0	7	5
274	R:R:K294	R:R:R297	1.24	No	No	0	3	5
275	R:R:V56	R:R:W55	1.23	No	No	0	6	4
276	R:R:F330	R:R:L326	1.22	No	No	0	3	5
277	R:R:L250	R:R:R299	1.21	Yes	No	0	8	8
278	R:R:R86	R:R:W80	1	No	No	0	8	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y61	7.55167	6	1	7
2	R:R:L69	3.465	4	0	6
3	R:R:N82	3.5325	4	0	6
4	R:R:M85	3.826	5	0	8
5	R:R:F92	3.6925	4	0	8
6	R:R:D100	7.205	4	0	9
7	R:R:C107	5	4	0	7
8	R:R:L108	7.9325	4	1	7
9	R:R:D115	5.6025	4	1	5
10	R:R:W120	8.31667	6	3	7
11	R:R:I130	2.6675	4	0	5
12	R:R:W153	7.368	5	0	8
13	R:R:M184	5.355	4	0	7
14	R:R:Q187	4.81	4	2	6
15	R:R:E212	7.56	5	2	4
16	R:R:W214	9.95667	6	2	4
17	R:R:Y223	8.25	4	0	8
18	R:R:Y232	6.0575	4	0	8
19	R:R:Y243	6.16	4	0	9
20	R:R:L250	2.536	5	7	8
21	R:R:F313	5.62	4	4	9
22	R:R:F333	5.195	4	0	4
23	R:R:F346	6.665	4	0	4
24	R:R:H350	5.37	4	1	5
25	R:R:Y354	6.132	5	1	7
26	R:R:I363	3.4975	4	5	8
27	R:R:Y364	6.035	4	5	9
28	R:R:F371	4.425	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:W351	R:R:Y61	10.2563	9.65	No	Yes	0	5	7
2	R:R:L112	R:R:Y61	15.2231	12.89	No	Yes	0	6	7
3	R:R:Y354	R:R:Y61	26.8306	4.96	Yes	Yes	1	7	7
4	R:R:F65	R:R:L108	13.5249	8.53	No	Yes	0	6	7
5	R:R:F65	R:R:L69	10.6032	3.65	No	Yes	0	6	6
6	R:R:C107	R:R:Y354	75.6224	4.03	Yes	Yes	0	7	7
7	R:R:C107	R:R:V103	100	5.12	Yes	No	0	7	7
8	R:R:S357	R:R:V103	99.6896	6.46	No	No	0	9	7
9	R:R:D100	R:R:S357	99.5618	5.89	Yes	No	0	9	9
10	R:R:D100	R:R:N72	43.8676	6.73	Yes	No	0	9	9
11	R:R:N72	R:R:S97	41.4815	8.94	No	No	0	9	9
12	R:R:S97	R:R:V75	37.7929	3.23	No	No	0	9	9
13	R:R:N365	R:R:V75	36.5451	5.91	No	No	0	7	9
14	R:R:F371	R:R:N365	31.5905	6.04	Yes	No	0	8	7
15	R:R:F371	R:R:M85	27.628	4.98	Yes	Yes	0	8	8
16	R:R:A78	R:R:M85	13.6344	1.61	No	Yes	0	8	8
17	R:R:A78	R:R:F375	12.1675	2.77	No	No	0	8	7
18	R:R:F375	R:R:L74	10.6884	2.44	No	No	0	7	6
19	R:R:D100	R:R:L96	78.3797	5.43	Yes	No	0	9	9
20	R:R:L145	R:R:L96	71.6842	5.54	No	No	0	9	9
21	R:R:L145	R:R:Y364	26.3132	8.21	No	Yes	0	9	9
22	R:R:I148	R:R:Y364	18.2178	6.04	No	Yes	0	8	9
23	R:R:F92	R:R:I148	17.5239	3.77	Yes	No	0	8	8
24	R:R:A169	R:R:F92	10.4328	2.77	No	Yes	0	7	8
25	R:R:L96	R:R:T144	13.3057	4.42	No	No	0	9	7
26	R:R:N95	R:R:T144	11.8753	5.85	No	No	0	9	7
27	R:R:D100	R:R:N360	10.8467	10.77	Yes	No	0	9	9
28	R:R:C107	R:R:Q134	47.3614	9.16	Yes	No	0	7	7
29	R:R:T111	R:R:Y354	30.7688	4.99	No	Yes	1	7	7
30	R:R:I116	R:R:L112	13.5796	2.85	No	No	0	5	6
31	R:R:I116	R:R:T117	11.924	3.04	No	No	0	5	5
32	R:R:E118	R:R:Y343	13.0805	4.49	No	No	0	4	3
33	L:L:I6	R:R:Y343	14.6631	4.84	No	No	0	0	3
34	L:L:I6	R:R:F346	16.0874	7.54	No	Yes	0	0	4
35	R:R:F346	R:R:H350	40.9885	5.66	Yes	Yes	0	4	5
36	R:R:E118	R:R:R339	11.4919	6.98	No	No	0	4	1
37	L:L:L7	R:R:Q134	13.3423	6.65	No	No	0	0	7
38	L:L:L7	R:R:W120	12.0214	3.42	No	Yes	0	0	7
39	R:R:I130	R:R:Q134	38.1886	4.12	Yes	No	0	5	7
40	R:R:I130	R:R:P131	35.4556	3.39	Yes	No	0	5	5
41	R:R:M191	R:R:P131	34.5913	5.03	No	No	0	6	5
42	R:R:M191	R:R:Q187	14.7483	4.08	No	Yes	2	6	6
43	R:R:Q187	R:R:T135	16.5135	7.09	Yes	No	0	6	6
44	R:R:M184	R:R:T135	15.1074	9.03	Yes	No	0	7	6
45	R:R:F313	R:R:L145	48.4387	3.65	Yes	No	0	9	9
46	R:R:P235	R:R:V142	12.7762	3.53	No	No	0	9	8
47	R:R:M239	R:R:Y243	28.5471	3.59	No	Yes	0	8	9
48	R:R:F313	R:R:M239	41.652	8.71	Yes	No	0	9	8
49	R:R:L306	R:R:Y243	27.7132	8.21	No	Yes	0	8	9
50	R:R:L306	R:R:T302	26.3984	2.95	No	No	0	8	8
51	R:R:L250	R:R:T302	25.2115	2.95	Yes	No	0	8	8
52	R:R:I246	R:R:L250	18.6804	2.85	No	Yes	7	9	8
53	R:R:C157	R:R:I246	17.3778	3.27	No	No	0	7	9
54	R:R:C157	R:R:W153	15.9839	7.84	No	Yes	0	7	8
55	R:R:F346	R:R:K327	29.5271	3.72	Yes	No	0	4	3
56	R:R:K327	R:R:R328	24.4507	18.56	No	No	0	3	4
57	R:R:H224	R:R:R328	14.5048	11.28	No	No	0	6	4
58	R:R:E212	R:R:M191	19.2282	4.06	Yes	No	2	4	6
59	R:R:E212	R:R:H224	13.6709	8.62	Yes	No	0	4	6
60	R:R:E212	R:R:W214	14.0666	14.17	Yes	Yes	2	4	4
61	L:L:G5	R:R:D211	12.971	5.03	No	No	0	0	5
62	R:R:D211	R:R:R328	14.4501	9.53	No	No	0	5	4
63	L:L:G5	R:R:V209	11.3762	3.68	No	No	0	0	5
64	R:R:V353	R:R:Y354	22.1499	3.79	No	Yes	0	7	7
65	R:R:I320	R:R:V353	21.3707	4.61	No	No	0	7	7
66	R:R:I320	R:R:S349	28.5593	3.1	No	No	0	7	6
67	R:R:P319	R:R:S349	27.1654	3.56	No	No	0	9	6
68	R:R:L318	R:R:P319	22.9107	4.93	No	No	0	6	9
69	R:R:L318	R:R:Y232	20.0134	4.69	No	Yes	0	6	8
70	R:R:F228	R:R:Y232	14.0727	7.22	No	Yes	0	6	8
71	R:R:L310	R:R:M239	17.39	2.83	No	No	0	8	8
72	R:R:L310	R:R:M307	14.5901	2.83	No	No	0	8	6
73	R:R:F247	R:R:M307	11.7414	6.22	No	No	0	6	6
74	R:R:H350	R:R:T111	28.3036	5.48	Yes	No	1	5	7
75	R:R:L108	R:R:Y354	14.8579	12.89	Yes	Yes	1	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:C107	R:R:Q134	9.16	0	Yes	No	7	7	2	1
R:R:E118	R:R:R339	6.98	0	No	No	4	1	2	1
R:R:E118	R:R:Y343	4.49	0	No	No	4	3	2	1
R:R:F122	R:R:W120	15.03	0	No	Yes	6	7	2	1
R:R:C127	R:R:W120	7.84	3	No	Yes	9	7	2	1
R:R:C193	R:R:W120	3.92	3	No	Yes	4	7	2	1
R:R:C210	R:R:W120	18.28	3	No	Yes	9	7	2	1
L:L:L7	R:R:W120	3.42	0	No	Yes	0	7	0	1
R:R:C127	R:R:C193	3.64	3	No	No	9	4	2	2
R:R:C127	R:R:C210	7.28	3	No	No	9	9	2	2
R:R:I130	R:R:Q134	4.12	0	Yes	No	5	7	2	1
L:L:L7	R:R:Q134	6.65	0	No	No	0	7	0	1
R:R:M184	R:R:T135	9.03	0	Yes	No	7	6	2	2
R:R:Q187	R:R:T135	7.09	2	Yes	No	6	6	1	2
L:L:M9	R:R:V138	7.61	0	No	No	0	6	0	1
R:R:F227	R:R:M184	4.98	0	No	Yes	5	7	1	2
R:R:M191	R:R:Q187	4.08	2	No	Yes	6	6	2	1
R:R:E212	R:R:Q187	3.82	2	Yes	Yes	4	6	2	1
L:L:T8	R:R:Q187	4.25	0	No	Yes	0	6	0	1
R:R:E212	R:R:M191	4.06	2	Yes	No	4	6	2	2
L:L:G5	R:R:V209	3.68	0	No	No	0	5	0	1
R:R:D211	R:R:R328	9.53	0	No	No	5	4	1	2
L:L:G5	R:R:D211	5.03	0	No	No	0	5	0	1
R:R:F227	R:R:T231	7.78	0	No	No	5	6	1	2
L:L:M9	R:R:F227	3.73	0	No	No	0	5	0	1
R:R:F346	R:R:L323	9.74	0	Yes	No	4	5	1	2
L:L:T8	R:R:N324	8.77	0	No	No	0	7	0	1
R:R:K327	R:R:R328	18.56	0	No	No	3	4	2	2
R:R:F333	R:R:K327	3.72	0	Yes	No	4	3	1	2
R:R:F346	R:R:K327	3.72	0	Yes	No	4	3	1	2
R:R:F333	R:R:V342	11.8	0	Yes	No	4	5	1	2
R:R:A334	R:R:H335	4.39	0	No	No	2	1	1	2
R:R:D338	R:R:T336	4.34	0	No	No	3	4	2	1
L:L:H2	R:R:T336	6.85	0	No	No	0	4	0	1
L:L:H2	R:R:R339	18.05	0	No	No	0	1	0	1
L:L:I6	R:R:Y343	4.84	0	No	No	0	3	0	1
R:R:F346	R:R:H350	5.66	0	Yes	Yes	4	5	1	2
L:L:I6	R:R:F346	7.54	0	No	Yes	0	4	0	1
L:L:A3	R:R:F333	2.77	0	No	Yes	0	4	0	1
R:R:F333	R:R:M332	2.49	0	Yes	No	4	3	1	2
L:L:A4	R:R:V209	1.7	0	No	No	0	5	0	1
R:R:S194	R:R:V209	1.62	0	No	No	3	5	2	1
L:L:N1	R:R:A334	1.56	0	No	No	0	2	0	1
R:R:G123	R:R:W120	1.41	0	No	Yes	8	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7L1U_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.1
Number of Linked Nodes	271
Number of Links	278
Number of Hubs	28
Number of Links mediated by Hubs	111
Number of Communities	7
Number of Nodes involved in Communities	29
Number of Links involved in Communities	34

Path Summary
Number Of Nodes in MetaPath	76
Number Of Links MetaPath	75
Number of Shortest Paths	32807
Length Of Smallest Path	3
Average Path Length	14.1432
Length of Longest Path	31
Minimum Path Strength	1.425
Average Path Strength	5.70803
Maximum Path Strength	19.92
Minimum Path Correlation	0.7
Average Path Correlation	0.930174
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	52.035
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	31.8673
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • molecular function activator activity • signaling receptor binding • neuropeptide activity • signaling receptor activator activity • hormone activity • protein binding • molecular function regulator activity • neuropeptide hormone activity • signaling receptor regulator activity • receptor ligand activity • type 2 orexin receptor binding • orexin receptor binding • G protein-coupled receptor binding • neuropeptide receptor binding • type 1 orexin receptor binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • negative regulation of potassium ion transport • regulation of localization • regulation of potassium ion transport
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • negative regulation of potassium ion transport • regulation of localization • regulation of potassium ion transport • transport • regulation of transport • negative regulation of monoatomic ion transport • regulation of monoatomic ion transport • negative regulation of biological process • negative regulation of transport • establishment of localization • metal ion transport • localization • monoatomic ion transport • potassium ion transport • monoatomic cation transport • regulation of metal ion transport • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • positive regulation of cell communication • multicellular organismal process • system process • nervous system process • regulation of system process • positive regulation of biological process • positive regulation of transmission of nerve impulse • transmission of nerve impulse • regulation of nervous system process • regulation of transmission of nerve impulse • positive regulation of nervous system process • positive regulation of multicellular organismal process • regulation of cell communication • regulation of multicellular organismal process • positive regulation of cellular process • negative regulation of nervous system process • negative regulation of transmission of nerve impulse • negative regulation of cell communication • negative regulation of cellular process • negative regulation of multicellular organismal process • behavior • eating behavior • feeding behavior • cellular localization • modulation of chemical synaptic transmission • synaptic signaling • regulation of secretion by cell • secretion by cell • signal release • establishment of localization in cell • trans-synaptic signaling • regulation of signaling • neurotransmitter secretion • secretion • regulation of neurotransmitter transport • export from cell • cell-cell signaling • neurotransmitter transport • regulation of secretion • chemical synaptic transmission • signal release from synapse • regulation of trans-synaptic signaling • regulation of neurotransmitter secretion • anterograde trans-synaptic signaling • sleep • regulation of postsynaptic membrane potential • chemical synaptic transmission, postsynaptic • cell surface receptor signaling pathway • excitatory postsynaptic potential • regulation of membrane potential • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • metabolic process • regulation of metabolic process • phospholipase C-activating G protein-coupled receptor signaling pathway • regulation of calcium ion transport • positive regulation of calcium ion transport • calcium ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • regulation of primary metabolic process • nucleobase-containing compound metabolic process • negative regulation of nucleobase-containing compound metabolic process • regulation of nucleobase-containing compound metabolic process • negative regulation of macromolecule metabolic process • negative regulation of DNA replication • negative regulation of metabolic process • primary metabolic process • regulation of macromolecule metabolic process • DNA metabolic process • nucleic acid metabolic process • DNA replication • negative regulation of DNA metabolic process • macromolecule metabolic process • regulation of DNA metabolic process • regulation of DNA replication • response to nutrient levels • response to stress • response to starvation • response to alcohol • response to chemical • response to oxygen-containing compound • membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • membrane-enclosed lumen • cytoplasmic vesicle lumen • endomembrane system • intracellular organelle lumen • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • neuronal dense core vesicle lumen • vesicle • neuronal dense core vesicle • vesicle lumen
Gene Ontology	Cellular Component	• membrane-bounded organelle • intracellular anatomical structure • intracellular vesicle • membrane-enclosed lumen • cytoplasmic vesicle lumen • endomembrane system • intracellular organelle lumen • intracellular organelle • cellular anatomical structure • cytoplasmic vesicle • neuronal dense core vesicle lumen • vesicle • neuronal dense core vesicle • vesicle lumen • dense core granule • intracellular membrane-bounded organelle • secretory granule lumen • organelle lumen • organelle • secretory granule • dense core granule lumen • secretory vesicle • cytoplasm • rough endoplasmic reticulum • endoplasmic reticulum • extracellular region • perinuclear region of cytoplasm • postsynapse • synapse • cell junction • transport vesicle • presynapse • synaptic vesicle • exocytic vesicle • peptide receptor activity • molecular transducer activity • orexin receptor activity • G protein-coupled receptor activity • G protein-coupled peptide receptor activity • signaling receptor activity • transmembrane signaling receptor activity • amide binding • binding • peptide hormone binding • hormone binding • neuropeptide receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • locomotion • phospholipase C-activating G protein-coupled receptor signaling pathway • rhythmic process • circadian sleep/wake cycle • multicellular organismal process • rhythmic behavior • circadian rhythm • regulation of circadian sleep/wake cycle • regulation of circadian sleep/wake cycle, wakefulness • regulation of circadian rhythm • behavior • regulation of behavior • circadian behavior • circadian sleep/wake cycle, wakefulness • regulation of multicellular organismal process • circadian sleep/wake cycle process • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • cell-cell signaling • chemical synaptic transmission • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to endogenous stimulus • response to chemical • cellular response to hormone stimulus • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • regulation of cytosolic calcium ion concentration • cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • feeding behavior • cell periphery • plasma membrane • membrane • nucleus • nucleoplasm • nuclear lumen • protein binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular space • extracellular membrane-bounded organelle • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O43614
Sequence	>7L1U_nogp_Chain_R H P K E Y E W V L I A G Y I I V F V V A L I G N V L V C V A V W K N H H M R T V T N Y F I V N L S L A D V L V T I T C L P A T L V V D I T E T W F F G Q S L C K V I P Y L Q T V S V S V S V L T L S C I A L D R W Y A I C H P L M F K S T A K R A R N S I V I I W I V S C I I M I P Q A I V M E C S T V F F T V C D E R W G G E I Y P K M Y H I C F F L V T Y M A P L C L M V L A Y L Q I F R K L W E I K Q I R A R R K T A R M L M V V L L V F A I C Y L P I S I L N V L K R V F G M F A H T E D R E T V Y A W F T F S H W L V Y A N S A A N P I I Y N F L S G K F R E E F K A A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5WQC	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	1.96	2017-11-29	doi.org/10.1016/j.str.2017.11.005
	5WS3	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	2.3	2017-12-13	doi.org/10.1016/j.str.2017.11.005
	7XRR	A	Peptide	Orexin	OX₂	Homo sapiens	Lemborexant	-	-	2.89	2022-11-23	doi.org/10.1016/j.str.2022.11.001
	6TPG	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	2.74	2020-01-01	doi.org/10.1021/acs.jmedchem.9b01787
	6TPJ	A	Peptide	Orexin	OX₂	Homo sapiens	Suvorexant	-	-	2.74	2020-01-01	doi.org/10.1021/acs.jmedchem.9b01787
	6TPN	A	Peptide	Orexin	OX₂	Homo sapiens	HTL6641	-	-	2.61	2020-01-01	doi.org/10.1021/acs.jmedchem.9b01787
	4S0V	A	Peptide	Orexin	OX₂	Homo sapiens	Suvorexant	-	-	2.5	2015-01-14	doi.org/10.1038/nature14035
	7L1U	A	Peptide	Orexin	OX₂	Homo sapiens	Orexin	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2021-02-10	doi.org/10.1038/s41467-021-21087-6
	7L1U (No Gprot)	A	Peptide	Orexin	OX₂	Homo sapiens	Orexin	-		3.2	2021-02-10	doi.org/10.1038/s41467-021-21087-6
	7L1V	A	Peptide	Orexin	OX₂	Homo sapiens	PubChem 155491009	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3	2021-02-10	doi.org/10.1038/s41467-021-21087-6
	7L1V (No Gprot)	A	Peptide	Orexin	OX₂	Homo sapiens	PubChem 155491009	-		3	2021-02-10	doi.org/10.1038/s41467-021-21087-6
	7SQO	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-	Gi1/β1/γ2	3.17	2022-05-25	doi.org/10.1038/s41467-022-30601-3
	7SQO (No Gprot)	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-		3.17	2022-05-25	doi.org/10.1038/s41467-022-30601-3
	7SR8	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	3.3	2022-06-08	doi.org/10.1038/s41467-022-30601-3
	7SR8 (No Gprot)	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-		3.3	2022-06-08	doi.org/10.1038/s41467-022-30601-3

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