psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:C1	L:L:C6	7.28	No	Yes	0	0	0
2	L:L:Y2	R:R:Q92	19.16	Yes	Yes	2	0	7
3	L:L:Y2	R:R:Q96	14.65	Yes	Yes	2	0	7
4	L:L:Y2	R:R:Q119	5.64	Yes	Yes	2	0	7
5	L:L:Y2	R:R:F291	5.16	Yes	Yes	0	0	7
6	L:L:I3	R:R:Q171	8.23	Yes	Yes	5	0	6
7	L:L:I3	R:R:Y200	3.63	Yes	No	5	0	7
8	L:L:I3	R:R:I201	2.94	Yes	Yes	0	0	5
9	L:L:I3	R:R:I204	4.42	Yes	No	5	0	5
10	L:L:N5	L:L:Q4	6.6	No	No	0	0	0
11	L:L:Q4	R:R:Q295	15.36	No	No	0	0	6
12	L:L:Q4	R:R:S298	7.22	No	No	0	0	5
13	L:L:N5	R:R:W188	13.56	No	No	0	0	3
14	L:L:C6	L:L:G9	3.92	Yes	No	4	0	0
15	L:L:?10	L:L:C6	3.93	Yes	Yes	4	0	0
16	L:L:L8	R:R:I312	4.28	No	No	0	0	4
17	L:L:?10	L:L:G9	4.23	Yes	No	4	0	0
18	L:L:?10	R:R:E42	9.84	Yes	No	4	0	5
19	L:L:?10	R:R:I312	3.53	Yes	No	4	0	4
20	L:L:?10	R:R:L316	3.43	Yes	No	0	0	5
21	R:R:L38	R:R:N35	6.87	No	No	0	5	5
22	R:R:E36	R:R:R40	15.12	No	No	0	5	5
23	R:R:E42	R:R:L38	6.63	No	No	0	5	5
24	R:R:E42	R:R:I312	4.1	No	No	4	5	4
25	R:R:I101	R:R:V43	3.07	No	No	0	5	6
26	R:R:L46	R:R:L97	8.3	No	No	0	6	7
27	R:R:C323	R:R:I49	3.27	No	No	0	7	7
28	R:R:L50	R:R:L54	6.92	No	No	0	6	6
29	R:R:L50	R:R:V93	4.47	No	No	0	6	7
30	R:R:L50	R:R:L94	5.54	No	No	0	6	8
31	R:R:C323	R:R:L52	4.76	No	No	0	7	5
32	R:R:A53	R:R:C323	3.61	No	No	0	8	7
33	R:R:D85	R:R:N57	6.73	Yes	No	3	9	9
34	R:R:L86	R:R:N57	5.49	No	No	0	7	9
35	R:R:N57	R:R:P326	6.52	No	No	3	9	9
36	R:R:C59	R:R:M330	3.24	No	No	0	6	7
37	R:R:S82	R:R:V60	9.7	No	No	0	9	9
38	R:R:M330	R:R:V60	3.04	No	No	0	7	9
39	R:R:A63	R:R:L336	4.73	No	No	0	7	8
40	R:R:F75	R:R:S72	5.28	No	No	0	9	8
41	R:R:D136	R:R:R73	7.15	No	No	0	9	7
42	R:R:R73	R:R:Y153	9.26	No	No	0	7	7
43	R:R:F75	R:R:L336	7.31	No	No	0	9	8
44	R:R:F76	R:R:F77	5.36	No	Yes	0	5	8
45	R:R:F76	R:R:R150	7.48	No	No	0	5	4
46	R:R:F76	R:R:Y153	6.19	No	No	0	5	7
47	R:R:F77	R:R:L132	6.09	Yes	No	0	8	7
48	R:R:F77	R:R:M133	8.71	Yes	No	0	8	8
49	R:R:D136	R:R:F77	10.75	No	Yes	0	9	8
50	R:R:M78	R:R:Y329	4.79	No	Yes	0	7	9
51	R:R:H80	R:R:L129	9	Yes	No	0	9	8
52	R:R:H80	R:R:V157	12.45	Yes	No	0	9	7
53	R:R:H80	R:R:W161	3.17	Yes	No	0	9	9
54	R:R:D85	R:R:L81	6.79	Yes	No	0	9	9
55	R:R:L129	R:R:L81	5.54	No	No	0	8	9
56	R:R:D85	R:R:S322	11.78	Yes	No	3	9	9
57	R:R:D85	R:R:P326	4.83	Yes	No	3	9	9
58	R:R:V87	R:R:W161	3.68	No	No	0	6	9
59	R:R:S126	R:R:V88	3.23	No	No	3	9	7
60	R:R:S322	R:R:V88	4.85	No	No	3	9	7
61	R:R:F91	R:R:V90	5.24	No	No	0	5	5
62	R:R:F91	R:R:L118	20.7	No	No	0	5	5
63	R:R:Q119	R:R:Q92	7.68	Yes	Yes	2	7	7
64	R:R:M123	R:R:Q92	16.31	No	Yes	0	6	7
65	R:R:Q92	R:R:S319	7.22	Yes	No	0	7	7
66	R:R:S319	R:R:V93	3.23	No	No	0	7	7
67	R:R:P95	R:R:Q96	6.32	No	Yes	2	4	7
68	R:R:P95	R:R:V115	3.53	No	No	2	4	6
69	R:R:P95	R:R:Q119	6.32	No	Yes	2	4	7
70	R:R:K116	R:R:Q96	4.07	No	Yes	2	4	7
71	R:R:Q119	R:R:Q96	11.52	Yes	Yes	2	7	7
72	R:R:I101	R:R:L97	4.28	No	No	0	5	7
73	R:R:L98	R:R:T102	4.42	No	No	0	4	6
74	R:R:R104	R:R:W99	6	No	No	0	5	5
75	R:R:D186	R:R:W99	8.93	No	No	0	4	5
76	R:R:D100	R:R:L316	4.07	No	No	0	5	5
77	R:R:R104	R:R:Y106	4.12	No	No	0	5	3
78	R:R:R104	R:R:V184	6.54	No	No	0	5	3
79	R:R:F105	R:R:G107	4.52	Yes	No	0	7	6
80	R:R:F105	R:R:L111	7.31	Yes	No	0	7	5
81	R:R:C112	R:R:F105	4.19	No	Yes	0	9	7
82	R:R:D186	R:R:F105	3.58	No	Yes	0	4	7
83	R:R:G107	R:R:P108	4.06	No	No	0	6	7
84	R:R:L111	R:R:P108	8.21	No	No	0	5	7
85	R:R:D109	R:R:R113	17.87	No	No	0	4	6
86	R:R:D109	R:R:L177	21.71	No	No	0	4	4
87	R:R:L111	R:R:V115	2.98	No	No	0	5	6
88	R:R:C112	R:R:C187	5.46	No	No	0	9	9
89	R:R:R113	R:R:V172	3.92	No	No	0	6	5
90	R:R:Q119	R:R:V115	4.3	Yes	No	2	7	6
91	R:R:K116	R:R:Q119	9.49	No	Yes	2	4	7
92	R:R:L165	R:R:Y117	7.03	No	Yes	0	3	7
93	R:R:S168	R:R:Y117	8.9	No	Yes	0	7	7
94	R:R:V172	R:R:Y117	6.31	No	Yes	0	5	7
95	R:R:S168	R:R:V120	6.46	No	No	0	7	5
96	R:R:Q171	R:R:V120	10.03	Yes	No	0	6	5
97	R:R:S168	R:R:V121	4.85	No	No	0	7	6
98	R:R:F124	R:R:Y128	11.35	Yes	No	0	6	6
99	R:R:A167	R:R:F124	8.32	No	Yes	0	5	6
100	R:R:F124	R:R:V208	5.24	Yes	No	0	6	5
101	R:R:A125	R:R:W161	5.19	No	No	0	7	9
102	R:R:S126	R:R:S322	3.26	No	No	3	9	9
103	R:R:P212	R:R:T127	3.5	No	No	0	9	8
104	R:R:F284	R:R:T127	3.89	No	No	1	9	8
105	R:R:T127	R:R:W288	4.85	No	Yes	1	8	8
106	R:R:C164	R:R:Y128	5.38	No	No	0	8	6
107	R:R:L130	R:R:N325	5.49	No	No	0	8	9
108	R:R:L131	R:R:V215	10.43	No	No	0	7	6
109	R:R:A156	R:R:L132	3.15	No	No	0	5	7
110	R:R:M133	R:R:Y329	7.18	No	Yes	0	8	9
111	R:R:L216	R:R:S134	3	Yes	No	1	8	8
112	R:R:C219	R:R:S134	3.44	Yes	No	0	6	8
113	R:R:S134	R:R:Y220	6.36	No	Yes	1	8	9
114	R:R:C219	R:R:L135	3.17	Yes	No	0	6	6
115	R:R:R137	R:R:Y220	5.14	No	Yes	0	9	9
116	R:R:C138	R:R:C219	7.28	No	Yes	0	7	6
117	R:R:C138	R:R:L222	3.17	No	No	0	7	6
118	R:R:C138	R:R:I223	4.91	No	No	0	7	8
119	R:R:L139	R:R:Q143	3.99	No	No	0	3	5
120	R:R:I141	R:R:I223	2.94	No	No	0	8	8
121	R:R:C142	R:R:K226	4.85	No	No	0	7	6
122	R:R:T152	R:R:Y153	3.75	No	No	0	7	7
123	R:R:F175	R:R:Q171	10.54	No	Yes	0	6	6
124	R:R:Q171	R:R:Y200	10.15	Yes	No	5	6	7
125	R:R:H173	R:R:I174	3.98	No	No	0	5	5
126	R:R:A189	R:R:F175	8.32	No	No	0	5	6
127	R:R:S176	R:R:V190	3.23	No	No	0	5	4
128	R:R:F185	R:R:L177	6.09	No	No	0	3	4
129	R:R:R178	R:R:W188	6	No	No	0	3	3
130	R:R:E179	R:R:F185	3.5	No	No	0	3	3
131	R:R:F191	R:R:P197	26.01	No	No	0	6	5
132	R:R:I192	R:R:Q193	10.98	No	Yes	0	4	4
133	R:R:P194	R:R:Q193	3.16	No	Yes	6	4	4
134	R:R:Q193	R:R:W195	13.14	Yes	No	6	4	2
135	R:R:G196	R:R:Q193	3.29	No	Yes	0	4	4
136	R:R:P194	R:R:W195	4.05	No	No	6	4	2
137	R:R:G196	R:R:P197	4.06	No	No	0	4	5
138	R:R:K198	R:R:V299	7.59	No	No	0	4	4
139	R:R:K198	R:R:W300	8.12	No	No	0	4	5
140	R:R:I204	R:R:Y200	13.3	No	No	5	5	7
141	R:R:I201	R:R:Q295	6.86	Yes	No	0	5	6
142	R:R:I201	R:R:M296	2.92	Yes	No	0	5	6
143	R:R:I201	R:R:V299	9.22	Yes	No	0	5	4
144	R:R:M296	R:R:T202	3.01	No	No	0	6	5
145	R:R:I204	R:R:W203	3.52	No	No	0	5	4
146	R:R:F292	R:R:T205	9.08	Yes	No	0	7	5
147	R:R:M296	R:R:T205	4.52	No	No	0	6	5
148	R:R:V208	R:R:W288	4.9	No	Yes	1	5	8
149	R:R:F292	R:R:V208	5.24	Yes	No	1	7	5
150	R:R:V213	R:R:Y209	5.05	No	Yes	1	6	8
151	R:R:I285	R:R:Y209	6.04	No	Yes	1	6	8
152	R:R:P212	R:R:V211	3.53	No	No	0	9	5
153	R:R:I285	R:R:V213	4.61	No	No	1	6	6
154	R:R:L216	R:R:Y220	4.69	Yes	Yes	1	8	9
155	R:R:I280	R:R:L216	4.28	Yes	Yes	1	8	8
156	R:R:F284	R:R:L216	3.65	No	Yes	1	9	8
157	R:R:M276	R:R:Y220	3.59	No	Yes	0	8	9
158	R:R:T277	R:R:Y220	7.49	No	Yes	0	8	9
159	R:R:I280	R:R:Y220	13.3	Yes	Yes	1	8	9
160	R:R:S224	R:R:T273	9.59	No	No	0	5	8
161	R:R:S224	R:R:T277	6.4	No	No	0	5	8
162	R:R:F225	R:R:Q229	4.68	No	No	0	4	5
163	R:R:K226	R:R:Q229	4.07	No	No	0	6	5
164	R:R:I227	R:R:K270	4.36	No	No	0	8	8
165	R:R:I227	R:R:T273	4.56	No	No	0	8	8
166	R:R:V274	R:R:W228	4.9	No	No	0	7	6
167	R:R:K275	R:R:R272	3.71	No	No	7	8	8
168	R:R:F332	R:R:R272	5.34	No	No	7	7	8
169	R:R:F332	R:R:K275	7.44	No	No	7	7	8
170	R:R:F332	R:R:M276	4.98	No	No	0	7	8
171	R:R:F278	R:R:L282	3.65	No	No	0	6	5
172	R:R:I279	R:R:I280	2.94	No	Yes	0	7	8
173	R:R:I280	R:R:Y329	4.84	Yes	Yes	0	8	9
174	R:R:F284	R:R:W288	15.03	No	Yes	1	9	8
175	R:R:C287	R:R:L320	3.17	No	No	0	8	5
176	R:R:C287	R:R:N321	9.45	No	No	0	8	9
177	R:R:F292	R:R:W288	6.01	Yes	Yes	1	7	8
178	R:R:N321	R:R:W288	14.69	No	Yes	0	9	8
179	R:R:P290	R:R:T289	5.25	No	No	0	9	6
180	R:R:F291	R:R:F292	9.65	Yes	Yes	0	7	7
181	R:R:F291	R:R:M315	3.73	Yes	No	0	7	6
182	R:R:A318	R:R:F291	8.32	No	Yes	0	7	7
183	R:R:F293	R:R:V294	3.93	No	No	0	5	5
184	R:R:F293	R:R:W297	6.01	No	No	0	5	4
185	R:R:F311	R:R:V294	10.49	No	No	0	4	5
186	R:R:V294	R:R:V314	4.81	No	No	0	5	5
187	R:R:K306	R:R:S298	4.59	No	No	0	4	5
188	R:R:N325	R:R:P326	3.26	No	No	0	9	9
189	R:R:N325	R:R:Y329	6.98	No	Yes	0	9	9
190	R:R:H335	R:R:T333	6.85	No	No	0	6	8
191	R:R:L336	R:R:T333	5.9	No	No	0	8	8
192	R:R:F337	R:R:H338	7.92	No	No	0	8	5
193	R:R:W288	R:R:Y209	2.89	Yes	Yes	1	8	8
194	R:R:L316	R:R:M315	2.83	No	No	0	5	6
195	R:R:A140	R:R:R73	2.77	No	No	0	8	7
196	R:R:L114	R:R:L118	2.77	No	No	0	5	5
197	R:R:A207	R:R:F124	2.77	No	Yes	0	4	6
198	R:R:A189	R:R:F191	2.77	No	No	0	5	6
199	R:R:D301	R:R:K306	2.77	No	No	0	4	4
200	R:R:L317	R:R:L320	2.77	No	No	0	7	5
201	R:R:D100	R:R:L46	2.71	No	No	0	5	6
202	R:R:P305	R:R:W297	2.7	No	No	0	4	4
203	R:R:A169	R:R:Y117	2.67	No	Yes	0	4	7
204	R:R:H80	R:R:I83	2.65	Yes	No	0	9	6
205	R:R:F311	R:R:S298	2.64	No	No	0	4	5
206	R:R:F91	R:R:V87	2.62	No	No	0	5	6
207	R:R:R178	R:R:V190	2.62	No	No	0	3	4
208	R:R:A199	R:R:W195	2.59	No	No	0	4	2
209	R:R:A304	R:R:W297	2.59	No	No	0	3	4
210	R:R:F191	R:R:I174	2.51	No	No	0	6	5
211	R:R:F337	R:R:L62	2.44	No	No	0	8	4
212	R:R:L62	R:R:R65	2.43	No	No	0	4	2
213	R:R:L74	R:R:R137	2.43	No	No	0	8	9
214	R:R:M330	R:R:W327	2.33	No	No	0	7	6
215	R:R:R150	R:R:R154	2.13	No	No	0	4	3
216	R:R:A125	R:R:G122	1.95	No	No	0	7	6
217	L:L:C6	L:L:P7	1.88	Yes	No	0	0	0
218	R:R:A169	R:R:P170	1.87	No	No	0	4	7
219	R:R:A308	R:R:P305	1.87	No	No	0	2	4
220	R:R:G56	R:R:S55	1.86	No	No	0	8	4
221	R:R:G221	R:R:S224	1.86	No	No	0	3	5
222	R:R:G163	R:R:V166	1.84	No	No	0	4	3
223	R:R:C219	R:R:V215	1.71	Yes	No	0	6	6
224	R:R:C287	R:R:V286	1.71	No	No	0	8	6
225	R:R:A217	R:R:V281	1.7	No	No	0	4	8
226	R:R:C219	R:R:T218	1.69	Yes	No	0	6	4
227	R:R:C324	R:R:I328	1.64	No	No	0	6	8
228	R:R:A283	R:R:I328	1.62	No	No	0	6	8
229	R:R:V41	R:R:V45	1.6	No	No	0	5	4
230	R:R:C47	R:R:L51	1.59	No	No	0	4	4
231	R:R:T160	R:R:V157	1.59	No	No	0	7	7
232	R:R:T273	R:R:V274	1.59	No	No	0	8	7
233	R:R:A89	R:R:L54	1.58	No	No	0	7	6
234	R:R:A84	R:R:L129	1.58	No	No	0	8	8
235	R:R:P144	R:R:Q143	1.58	No	No	0	9	5
236	R:R:A39	R:R:N35	1.56	No	No	0	5	5
237	R:R:I49	R:R:S319	1.55	No	No	0	7	7
238	R:R:I285	R:R:V281	1.54	No	No	0	6	8
239	R:R:C142	R:R:Q143	1.53	No	No	0	7	5
240	R:R:I214	R:R:T218	1.52	No	No	0	3	4
241	R:R:L38	R:R:S309	1.5	No	No	0	5	2
242	R:R:L162	R:R:V166	1.49	No	No	0	4	3
243	R:R:L206	R:R:V211	1.49	No	No	0	5	5
244	R:R:I279	R:R:I328	1.47	No	No	0	7	8
245	R:R:I83	R:R:K79	1.45	No	No	0	6	6
246	R:R:I210	R:R:L206	1.43	No	No	0	5	5
247	R:R:I313	R:R:L317	1.43	No	No	0	5	7
248	R:R:A39	R:R:F103	1.39	No	No	0	5	4
249	R:R:L48	R:R:L51	1.38	No	No	0	4	4
250	R:R:L51	R:R:L52	1.38	No	No	0	4	5
251	L:L:L8	R:R:E307	1.33	No	No	0	0	4
252	R:R:T289	R:R:Y209	1.25	No	Yes	0	6	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:Y2	11.1525	4	2	0
2	L:L:I3	4.805	4	5	0
3	L:L:C6	4.2525	4	4	0
4	L:L:?10	4.992	5	4	0
5	R:R:F77	7.7275	4	0	8
6	R:R:H80	6.8175	4	0	9
7	R:R:D85	7.5325	4	3	9
8	R:R:Q92	12.5925	4	2	7
9	R:R:Q96	9.14	4	2	7
10	R:R:F105	4.9	4	0	7
11	R:R:Y117	6.2275	4	0	7
12	R:R:Q119	7.49167	6	2	7
13	R:R:F124	6.92	4	0	6
14	R:R:Q171	9.7375	4	5	6
15	R:R:Q193	7.6425	4	6	4
16	R:R:I201	5.485	4	0	5
17	R:R:Y209	3.8075	4	1	8
18	R:R:L216	3.905	4	1	8
19	R:R:C219	3.458	5	0	6
20	R:R:Y220	6.76167	6	1	9
21	R:R:I280	6.34	4	1	8
22	R:R:W288	8.06167	6	1	8
23	R:R:F291	6.715	4	0	7
24	R:R:F292	7.495	4	1	7
25	R:R:Y329	5.9475	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?10	R:R:L316	26.9866	3.43	Yes	No	0	0	5
2	R:R:L316	R:R:M315	37.2291	2.83	No	No	0	5	6
3	R:R:F291	R:R:M315	38.6145	3.73	Yes	No	0	7	6
4	L:L:Y2	R:R:F291	59.1687	5.16	Yes	Yes	0	0	7
5	L:L:Y2	R:R:Q92	26.4127	19.16	Yes	Yes	2	0	7
6	L:L:Y2	R:R:Q119	26.9866	5.64	Yes	Yes	2	0	7
7	R:R:F291	R:R:F292	85.6408	9.65	Yes	Yes	0	7	7
8	R:R:F292	R:R:T205	83.6022	9.08	Yes	No	0	7	5
9	R:R:M296	R:R:T205	82.5928	4.52	No	No	0	6	5
10	R:R:I201	R:R:M296	80.5146	2.92	Yes	No	0	5	6
11	L:L:I3	R:R:I201	53.1222	2.94	Yes	Yes	0	0	5
12	L:L:I3	R:R:Q171	46.957	8.23	Yes	Yes	5	0	6
13	R:R:I201	R:R:Q295	33.5082	6.86	Yes	No	0	5	6
14	L:L:Q4	R:R:Q295	31.7467	15.36	No	No	0	0	6
15	L:L:Q4	R:R:S298	21.425	7.22	No	No	0	0	5
16	L:L:?10	R:R:E42	11.9842	9.84	Yes	No	4	0	5
17	R:R:E42	R:R:L38	10.1831	6.63	No	No	0	5	5
18	R:R:Q92	R:R:S319	25.334	7.22	Yes	No	0	7	7
19	R:R:I49	R:R:S319	14.0524	1.55	No	No	0	7	7
20	R:R:C323	R:R:I49	12.1029	3.27	No	No	0	7	7
21	R:R:S319	R:R:V93	10.1336	3.23	No	No	0	7	7
22	R:R:F292	R:R:W288	100	6.01	Yes	Yes	1	7	8
23	R:R:F284	R:R:W288	92.7758	15.03	No	Yes	1	9	8
24	R:R:F284	R:R:L216	95.5962	3.65	No	Yes	1	9	8
25	R:R:I280	R:R:L216	64.3741	4.28	Yes	Yes	1	8	8
26	R:R:I280	R:R:Y329	68.5304	4.84	Yes	Yes	0	8	9
27	R:R:N325	R:R:Y329	47.9664	6.98	No	Yes	0	9	9
28	R:R:N325	R:R:P326	44.7501	3.26	No	No	0	9	9
29	R:R:D85	R:R:P326	39.0401	4.83	Yes	No	3	9	9
30	R:R:M133	R:R:Y329	23.7011	7.18	No	Yes	0	8	9
31	R:R:F77	R:R:M133	21.9693	8.71	Yes	No	0	8	8
32	R:R:F76	R:R:F77	10.0643	5.36	No	Yes	0	5	8
33	R:R:D85	R:R:L81	32.0732	6.79	Yes	No	0	9	9
34	R:R:L129	R:R:L81	30.1831	5.54	No	No	0	8	9
35	R:R:H80	R:R:L129	26.3137	9	Yes	No	0	9	8
36	R:R:H80	R:R:W161	16.6254	3.17	Yes	No	0	9	9
37	R:R:V87	R:R:W161	10.7076	3.68	No	No	0	6	9
38	R:R:Q119	R:R:V115	24.5225	4.3	Yes	No	2	7	6
39	R:R:L111	R:R:V115	23.2162	2.98	No	No	0	5	6
40	R:R:F105	R:R:L111	17.5062	7.31	Yes	No	0	7	5
41	R:R:D186	R:R:F105	10.1336	3.58	No	Yes	0	4	7
42	R:R:Q171	R:R:V120	25.6507	10.03	Yes	No	0	6	5
43	R:R:S168	R:R:V120	23.8595	6.46	No	No	0	7	5
44	R:R:S168	R:R:Y117	20.0792	8.9	No	Yes	0	7	7
45	R:R:V172	R:R:Y117	12.281	6.31	No	Yes	0	5	7
46	R:R:R113	R:R:V172	10.282	3.92	No	No	0	6	5
47	R:R:F124	R:R:V208	10.1831	5.24	Yes	No	0	6	5
48	R:R:L216	R:R:S134	19.8615	3	Yes	No	1	8	8
49	R:R:C219	R:R:S134	24.2058	3.44	Yes	No	0	6	8
50	R:R:L216	R:R:Y220	20.0396	4.69	Yes	Yes	1	8	9
51	R:R:F175	R:R:Q171	23.8595	10.54	No	Yes	0	6	6
52	R:R:A189	R:R:F175	21.9792	8.32	No	No	0	5	6
53	R:R:A189	R:R:F191	20.0792	2.77	No	No	0	5	6
54	R:R:F191	R:R:P197	14.2603	26.01	No	No	0	6	5
55	R:R:G196	R:R:P197	12.281	4.06	No	No	0	4	5
56	R:R:G196	R:R:Q193	10.282	3.29	No	Yes	0	4	4
57	R:R:W288	R:R:Y209	14.1217	2.89	Yes	Yes	1	8	8
58	R:R:T277	R:R:Y220	16.0614	7.49	No	Yes	0	8	9
59	R:R:S224	R:R:T277	14.1217	6.4	No	No	0	5	8
60	R:R:S224	R:R:T273	10.1831	9.59	No	No	0	5	8
61	R:R:N321	R:R:W288	11.8654	14.69	No	Yes	0	9	8
62	R:R:F311	R:R:S298	15.7348	2.64	No	No	0	4	5
63	R:R:F311	R:R:V294	14.0722	10.49	No	No	0	4	5
64	R:R:F293	R:R:V294	10.1633	3.93	No	No	0	5	5
65	R:R:I280	R:R:Y220	10.8461	13.3	Yes	Yes	1	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y2	R:R:Q92	19.16	2	Yes	Yes	0	7	0	1
L:L:Y2	R:R:Q96	14.65	2	Yes	Yes	0	7	0	1
L:L:Y2	R:R:Q119	5.64	2	Yes	Yes	0	7	0	1
L:L:Y2	R:R:F291	5.16	2	Yes	Yes	0	7	0	1
L:L:I3	R:R:Q171	8.23	5	Yes	Yes	0	6	0	1
L:L:I3	R:R:Y200	3.63	5	Yes	No	0	7	0	1
L:L:I3	R:R:I201	2.94	5	Yes	Yes	0	5	0	1
L:L:I3	R:R:I204	4.42	5	Yes	No	0	5	0	1
L:L:Q4	R:R:Q295	15.36	0	No	No	0	6	0	1
L:L:Q4	R:R:S298	7.22	0	No	No	0	5	0	1
L:L:N5	R:R:W188	13.56	0	No	No	0	3	0	1
L:L:L8	R:R:I312	4.28	0	No	No	0	4	0	1
L:L:?10	R:R:E42	9.84	4	Yes	No	0	5	0	1
L:L:?10	R:R:I312	3.53	4	Yes	No	0	4	0	1
L:L:?10	R:R:L316	3.43	4	Yes	No	0	5	0	1
R:R:E42	R:R:L38	6.63	4	No	No	5	5	1	2
R:R:E42	R:R:I312	4.1	4	No	No	5	4	1	1
R:R:Q119	R:R:Q92	7.68	2	Yes	Yes	7	7	1	1
R:R:M123	R:R:Q92	16.31	0	No	Yes	6	7	2	1
R:R:Q92	R:R:S319	7.22	2	Yes	No	7	7	1	2
R:R:P95	R:R:Q96	6.32	2	No	Yes	4	7	2	1
R:R:P95	R:R:V115	3.53	2	No	No	4	6	2	2
R:R:P95	R:R:Q119	6.32	2	No	Yes	4	7	2	1
R:R:K116	R:R:Q96	4.07	2	No	Yes	4	7	2	1
R:R:Q119	R:R:Q96	11.52	2	Yes	Yes	7	7	1	1
R:R:D100	R:R:L316	4.07	0	No	No	5	5	2	1
R:R:Q119	R:R:V115	4.3	2	Yes	No	7	6	1	2
R:R:K116	R:R:Q119	9.49	2	No	Yes	4	7	2	1
R:R:Q171	R:R:V120	10.03	5	Yes	No	6	5	1	2
R:R:F175	R:R:Q171	10.54	0	No	Yes	6	6	2	1
R:R:Q171	R:R:Y200	10.15	5	Yes	No	6	7	1	1
R:R:R178	R:R:W188	6	0	No	No	3	3	2	1
R:R:I204	R:R:Y200	13.3	5	No	No	5	7	1	1
R:R:I201	R:R:Q295	6.86	0	Yes	No	5	6	1	1
R:R:I201	R:R:M296	2.92	0	Yes	No	5	6	1	2
R:R:I201	R:R:V299	9.22	0	Yes	No	5	4	1	2
R:R:I204	R:R:W203	3.52	5	No	No	5	4	1	2
R:R:F291	R:R:F292	9.65	0	Yes	Yes	7	7	1	2
R:R:F291	R:R:M315	3.73	0	Yes	No	7	6	1	2
R:R:A318	R:R:F291	8.32	0	No	Yes	7	7	2	1
R:R:K306	R:R:S298	4.59	0	No	No	4	5	2	1
R:R:L316	R:R:M315	2.83	0	No	No	5	6	1	2
R:R:F311	R:R:S298	2.64	0	No	No	4	5	2	1
L:L:L8	R:R:E307	1.33	0	No	No	0	4	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7QVM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.92
Number of Linked Nodes	243
Number of Links	252
Number of Hubs	25
Number of Links mediated by Hubs	92
Number of Communities	7
Number of Nodes involved in Communities	40
Number of Links involved in Communities	51

Path Summary
Number Of Nodes in MetaPath	66
Number Of Links MetaPath	65
Number of Shortest Paths	21913
Length Of Smallest Path	3
Average Path Length	12.8901
Length of Longest Path	31
Minimum Path Strength	1.38
Average Path Strength	6.34831
Maximum Path Strength	19.79
Minimum Path Correlation	0.7
Average Path Correlation	0.910959
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	42.8693
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.4922
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • mu-type opioid receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • opioid receptor binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • peptide hormone receptor binding • corticotropin-releasing hormone receptor binding • corticotropin-releasing hormone receptor 1 binding • hormone receptor binding • neuropeptide receptor binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cation binding • metal ion binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • heart process • multicellular organismal process • system process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • regulation of multicellular organismal process • heart contraction • blood circulation • behavior • locomotory behavior • transport • secretion • export from cell • membrane docking • establishment of localization • vesicle-mediated transport • localization • organelle localization by membrane tethering • secretion by cell • exocytosis • organelle localization • vesicle docking • exocytic process • vesicle docking involved in exocytosis • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • protein localization • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • negative regulation of secretion • cellular macromolecule localization • negative regulation of hormone secretion • negative regulation of secretion by cell • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • regulation of peptide transport • regulation of establishment of protein localization • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • trans-synaptic signaling • modulation of chemical synaptic transmission • chemical synaptic transmission • synaptic signaling • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • postsynaptic modulation of chemical synaptic transmission • muscle contraction • muscle system process • cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex
Gene Ontology	Cellular Component	• cell periphery • postsynapse • cellular anatomical structure • postsynaptic membrane • synapse • cell junction • membrane • plasma membrane • plasma membrane region • synaptic membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • parallel fiber to Purkinje cell synapse • excitatory synapse • presynapse • presynaptic membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • intracellular anatomical structure • cytoplasm • GABA-ergic synapse • glutamatergic synapse • cell body • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • G-protein beta-subunit binding • fibroblast proliferation • molecular transducer activity • molecular function activator activity • signaling receptor binding • signaling receptor activity • neuropeptide activity • signaling receptor activator activity • hormone activity • neurohypophyseal hormone activity • molecular function regulator activity • neuropeptide hormone activity • signaling receptor regulator activity • receptor ligand activity • vasopressin receptor binding • V1A vasopressin receptor binding • G protein-coupled receptor binding • oxytocin receptor binding • heart process • regulation of heart contraction • regulation of system process • circulatory system process • regulation of blood circulation • regulation of multicellular organismal process • regulation of biological quality • heart contraction • blood circulation • regulation of heart rate • regulation of penile erection • regulation of reproductive process • reproductive process • multicellular organismal reproductive process • positive regulation of biological process • mating behavior • behavior • positive regulation of penile erection • positive regulation of multicellular organismal process • reproductive behavior • penile erection • copulation • positive regulation of reproductive process • heart development • circulatory system development • response to steroid hormone • response to progesterone • learning or memory • cognition • memory • male mating behavior • drinking behavior • feeding behavior • multi-multicellular organism process • sperm ejaculation • insemination • multi-organism reproductive process • response to electrical stimulus • response to abiotic stimulus • maternal aggressive behavior • aggressive behavior • response to organophosphorus • response to purine-containing compound • response to cAMP • positive regulation of cell communication • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • positive regulation of synaptic transmission • chemical synaptic transmission • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • positive regulation of cellular process • positive regulation of signaling • response to ether • positive regulation of cytosolic calcium ion concentration • positive regulation of nervous system development • positive regulation of cellular component organization • regulation of cellular component organization • regulation of developmental process • regulation of nervous system development • positive regulation of developmental process • cellular component organization • cellular component biogenesis • cellular component assembly • cell junction assembly • regulation of synapse structure or activity • synapse organization • cellular component organization or biogenesis • regulation of synapse assembly • regulation of multicellular organismal development • positive regulation of cellular component biogenesis • nervous system development • regulation of cellular component biogenesis • regulation of cell junction assembly • positive regulation of cell junction assembly • regulation of synapse organization • cell junction organization • synapse assembly • positive regulation of synapse assembly • response to peptide hormone • female pregnancy • maternal behavior • parental behavior • response to activity • regulation of blood pressure • positive regulation of blood pressure • regulation of hindgut contraction • positive regulation of smooth muscle contraction • digestive system process • smooth muscle contraction • regulation of smooth muscle contraction • positive regulation of digestive system process • positive regulation of hindgut contraction • regulation of digestive system process • muscle contraction • muscle system process • regulation of muscle system process • hindgut contraction • digestion • regulation of muscle contraction • positive regulation of muscle contraction • positive regulation of uterine smooth muscle contraction • uterine smooth muscle contraction • regulation of uterine smooth muscle contraction • eating behavior • response to retinoic acid • regulation of body fluid levels • renal system process • regulation of urine volume • negative regulation of urine volume • response to carbohydrate • response to sucrose • response to disaccharide • response to corticosteroid • response to glucocorticoid • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • metabolic process • regulation of metabolic process • biological process involved in intraspecies interaction between organisms • social behavior • positive regulation of female receptivity • female mating behavior • regulation of female receptivity • ossification • positive regulation of ossification • regulation of ossification • response to amine • response to amphetamine • regulation of localization • localization • regulation of prostaglandin secretion • monocarboxylic acid transport • fatty acid transport • prostaglandin secretion • positive regulation of icosanoid secretion • carboxylic acid transport • lipid transport • establishment of localization • regulation of fatty acid transport • regulation of secretion • organic acid transport • positive regulation of lipid transport • lipid export from cell • prostaglandin transport • transport • regulation of lipid transport • positive regulation of secretion by cell • regulation of secretion by cell • secretion by cell • positive regulation of secretion • icosanoid transport • signal release • regulation of icosanoid secretion • positive regulation of prostaglandin secretion • icosanoid secretion • organic anion transport • regulation of transport • secretion • export from cell • lipid localization • positive regulation of lipid localization • positive regulation of organic acid transport • positive regulation of transport • regulation of lipid localization • macromolecule localization • regulation of organic acid transport • positive regulation of fatty acid transport • grooming behavior • response to cocaine • response to alkaloid • response to nutrient levels • response to food • response to estradiol • negative regulation of blood pressure • monoamine transport • nitrogen compound transport • regulation of catecholamine secretion • organic hydroxy compound transport • positive regulation of amine transport • catecholamine transport • norepinephrine transport • positive regulation of catecholamine secretion • positive regulation of norepinephrine secretion • organic cation transport • catecholamine secretion • amine transport • norepinephrine secretion • regulation of amine transport • regulation of norepinephrine secretion • dense core granule • intracellular vesicle • endomembrane system • cytoplasmic vesicle • secretory granule • secretory vesicle • neuronal dense core vesicle • axon • axon terminus • distal axon • terminal bouton • neuron projection terminus • peptide receptor activity • G protein-coupled receptor activity • oxytocin receptor activity • G protein-coupled peptide receptor activity • transmembrane signaling receptor activity • amide binding • peptide hormone binding • hormone binding • vasopressin receptor activity • ionotropic glutamate receptor binding • glutamate receptor binding • response to xenobiotic stimulus • ovulation cycle • rhythmic process • estrous cycle • regulation of tube diameter • regulation of tube size • positive regulation of vasoconstriction • vascular process in circulatory system • regulation of vasoconstriction • blood vessel diameter maintenance • vasoconstriction • regulation of anatomical structure size • suckling behavior • response to decreased oxygen levels • response to anoxia • response to stress • response to oxygen levels • mammary gland development • gland development • body fluid secretion • lactation • maternal process involved in parturition • parturition • synaptic transmission, glutamatergic • regulation of synaptic transmission, glutamatergic • positive regulation of synaptic transmission, glutamatergic • MAPK cascade • ERK1 and ERK2 cascade • positive regulation of synaptic transmission, GABAergic • synaptic transmission, GABAergic • regulation of synaptic transmission, GABAergic • digestive system development • tube development • digestive tract development • response to peptide • response to cytokine • regulation of systemic arterial blood pressure by hormone • regulation of systemic arterial blood pressure mediated by a chemical signal • regulation of systemic arterial blood pressure • endocrine process • regulation of systemic arterial blood pressure by vasopressin • cell surface receptor signaling pathway • head development • forebrain development • brain development • central nervous system development • telencephalon development • cell-cell junction • adherens junction • anchoring junction • actin-based cell projection • microvillus • apical part of cell • apical plasma membrane
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?10
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P30559
Sequence	>7QVM_nogp_Chain_R N E A L A R V E V A V L C L I L L L A L S G N A C V L L A L R T T R Q K H S R L F F F M K H L S I A D L V V A V F Q V L P Q L L W D I T F R F Y G P D L L C R L V K Y L Q V V G M F A S T Y L L L L M S L D R C L A I C Q P R R T Y R L A V L A T W L G C L V A S A P Q V H I F S L R E V F D C W A V F I Q P W G P K A Y I T W I T L A V Y I V P V I V L A T C Y G L I S F K I W Q N K I R T V K M T F I I V L A F I V C W T P F F F V Q M W S V W D A N A P K E A S A F I I V M L L A S L N S C C N P W I Y M L F T G H L F H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody-E	-	-	3.2	2023-12-27	10.1101/2023.12.06.570395
	7QVM	A	Peptide	Vasopressin and Oxytocin	OT	Homo sapiens	Oxytocin	-	chim(NtGi1-Go-CtGq)/β1/γ2	3.25	2022-08-10	10.1038/s41467-022-31325-0
	7QVM (No Gprot)	A	Peptide	Vasopressin and Oxytocin	OT	Homo sapiens	Oxytocin	-		3.25	2022-08-10	10.1038/s41467-022-31325-0
	7RYC	A	Peptide	Vasopressin and Oxytocin	OT	Homo sapiens	Oxytocin	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	2.9	2022-03-09	10.1038/s41594-022-00728-4
	7RYC (No Gprot)	A	Peptide	Vasopressin and Oxytocin	OT	Homo sapiens	Oxytocin	-		2.9	2022-03-09	10.1038/s41594-022-00728-4
	6TPK	A	Peptide	Vasopressin and Oxytocin	OT	Homo sapiens	Retosiban	-	-	3.2	2020-08-05	10.1126/sciadv.abb5419
	6TOT	A	Peptide	Orexin	OX₁	Homo sapiens	Lemborexant	-	-	2.22	2020-01-15	10.1021/acs.jmedchem.9b01787
	6OT0	F	Protein	Frizzled	SMO	Homo sapiens	-	25(S)-Epoxycholesterol	Gi1/β1/γ2	3.84	2019-06-12	10.1038/s41586-019-1286-0
	6OT0 (No Gprot)	F	Protein	Frizzled	SMO	Homo sapiens	-	25(S)-Epoxycholesterol		3.84	2019-06-12	10.1038/s41586-019-1286-0

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Download 7QVM_nogp.zip

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