psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:I23	5.49	Yes	No	1	0	6
2	L:L:?1	R:R:P24	15.8	Yes	No	1	0	7
3	L:L:?1	R:R:M27	10.88	Yes	No	1	0	8
4	L:L:?1	R:R:T69	5.67	Yes	Yes	0	0	8
5	L:L:?1	R:R:S73	4.34	Yes	No	0	0	8
6	L:L:?1	R:R:T79	8.51	Yes	No	0	0	7
7	L:L:?1	R:R:L99	6.66	Yes	No	0	0	8
8	L:L:?1	R:R:T168	9.93	Yes	Yes	1	0	6
9	L:L:?1	R:R:W169	23.02	Yes	Yes	1	0	5
10	L:L:?1	R:R:I315	6.87	Yes	No	1	0	6
11	L:L:?1	R:R:S319	2.89	Yes	No	1	0	8
12	L:L:?1	R:R:I323	2.75	Yes	No	1	0	8
13	R:R:I23	R:R:P24	3.39	No	No	1	6	7
14	R:R:I23	R:R:R316	6.26	No	Yes	1	6	7
15	R:R:M27	R:R:V26	6.09	No	No	1	8	5
16	R:R:R316	R:R:V26	5.23	Yes	No	1	7	5
17	R:R:M27	R:R:R316	11.17	No	Yes	1	8	7
18	R:R:F28	R:R:I29	3.77	No	No	0	6	5
19	R:R:F28	R:R:S73	5.28	No	No	0	6	8
20	R:R:F28	R:R:I77	11.3	No	No	0	6	6
21	R:R:L70	R:R:V32	4.47	No	No	0	5	7
22	R:R:I39	R:R:N35	5.66	Yes	Yes	3	8	9
23	R:R:D65	R:R:N35	6.73	Yes	Yes	0	9	9
24	R:R:L66	R:R:N35	17.85	No	Yes	3	8	9
25	R:R:L36	R:R:V40	2.98	No	No	0	5	5
26	R:R:I39	R:R:L66	2.85	Yes	No	3	8	8
27	R:R:I330	R:R:V41	7.68	No	No	0	8	7
28	R:R:L42	R:R:Y55	5.86	Yes	No	0	8	8
29	R:R:L42	R:R:V58	2.98	Yes	No	0	8	8
30	R:R:I330	R:R:L42	4.28	No	Yes	0	8	8
31	R:R:E48	R:R:R46	11.63	No	No	0	7	5
32	R:R:E48	R:R:Q49	14.02	No	No	0	7	6
33	R:R:K50	R:R:Y55	5.97	No	No	0	7	8
34	R:R:E51	R:R:K133	17.55	No	No	0	7	5
35	R:R:F54	R:R:V58	3.93	No	No	0	8	8
36	R:R:F54	R:R:M113	9.95	No	No	0	8	9
37	R:R:L57	R:R:T56	2.95	No	No	4	8	6
38	R:R:K133	R:R:T56	4.5	No	No	0	5	6
39	R:R:A136	R:R:T56	3.36	No	No	4	8	6
40	R:R:A136	R:R:L57	3.15	No	No	4	8	8
41	R:R:L140	R:R:L57	4.15	No	No	0	8	8
42	R:R:V58	R:R:Y329	5.05	No	Yes	0	8	9
43	R:R:C59	R:R:G60	3.92	No	No	0	6	8
44	R:R:I109	R:R:L61	7.14	No	No	0	8	9
45	R:R:F102	R:R:T64	2.59	Yes	No	0	7	9
46	R:R:S105	R:R:T64	6.4	No	No	0	8	9
47	R:R:T64	R:R:Y144	6.24	No	No	0	9	8
48	R:R:D65	R:R:T69	2.89	Yes	Yes	0	9	8
49	R:R:D65	R:R:P322	3.22	Yes	Yes	0	9	9
50	R:R:D65	R:R:P326	4.83	Yes	No	0	9	9
51	R:R:L67	R:R:L71	4.15	No	No	0	7	6
52	R:R:F102	R:R:G68	10.54	Yes	No	0	7	8
53	R:R:L70	R:R:T69	2.95	No	Yes	0	5	8
54	R:R:F102	R:R:T69	2.59	Yes	Yes	0	7	8
55	R:R:L71	R:R:V72	2.98	No	Yes	5	6	7
56	R:R:I98	R:R:L71	2.85	No	No	5	5	6
57	R:R:V72	R:R:V75	3.21	Yes	No	0	7	7
58	R:R:I98	R:R:V72	9.22	No	Yes	5	5	7
59	R:R:P74	R:R:S73	5.34	No	No	0	9	8
60	R:R:A78	R:R:I77	3.25	No	No	0	6	6
61	R:R:M81	R:R:Q89	2.72	No	Yes	0	4	2
62	R:R:C92	R:R:Q89	7.63	No	Yes	0	9	2
63	R:R:L163	R:R:Q89	6.65	Yes	Yes	0	4	2
64	R:R:C170	R:R:C92	7.28	No	No	0	9	9
65	R:R:F101	R:R:F97	4.29	No	No	0	7	7
66	R:R:C151	R:R:F97	6.98	No	No	0	8	7
67	R:R:F171	R:R:L99	3.65	No	No	0	6	8
68	R:R:C151	R:R:L100	3.17	No	Yes	0	8	7
69	R:R:L100	R:R:P154	3.28	Yes	No	0	7	9
70	R:R:F171	R:R:L100	6.09	No	Yes	0	6	7
71	R:R:L100	R:R:Y188	4.69	Yes	No	0	7	7
72	R:R:F101	R:R:N147	8.46	No	No	0	7	8
73	R:R:F101	R:R:V148	2.62	No	No	0	7	4
74	R:R:F102	R:R:P322	11.56	Yes	Yes	0	7	9
75	R:R:L104	R:R:S108	3	No	No	0	8	7
76	R:R:L104	R:R:N147	10.98	No	No	0	8	8
77	R:R:F191	R:R:L104	4.87	No	No	0	6	8
78	R:R:S105	R:R:S108	3.26	No	No	0	8	7
79	R:R:I109	R:R:S105	3.1	No	No	0	8	8
80	R:R:I196	R:R:L107	2.85	Yes	No	6	7	8
81	R:R:L107	R:R:S285	7.51	No	No	6	8	8
82	R:R:S108	R:R:V143	3.23	No	No	0	7	7
83	R:R:I110	R:R:T199	4.56	No	Yes	0	8	8
84	R:R:D325	R:R:I110	2.8	No	No	0	9	8
85	R:R:I110	R:R:Y329	2.42	No	Yes	0	8	9
86	R:R:C111	R:R:L195	4.76	No	No	0	7	8
87	R:R:C111	R:R:T199	3.38	No	Yes	0	7	8
88	R:R:M113	R:R:Y329	7.18	No	Yes	0	9	9
89	R:R:R117	R:R:S114	7.91	No	Yes	0	9	9
90	R:R:S114	R:R:T199	3.2	Yes	Yes	0	9	8
91	R:R:N203	R:R:S114	5.96	Yes	Yes	0	9	9
92	R:R:C202	R:R:V115	3.42	No	No	0	7	7
93	R:R:E116	R:R:R117	3.49	No	No	0	9	9
94	R:R:E116	R:R:Y127	6.73	No	No	0	9	8
95	R:R:L274	R:R:R117	2.43	No	No	0	8	9
96	R:R:N122	R:R:Y118	17.44	No	Yes	7	7	8
97	R:R:H123	R:R:Y118	5.44	No	Yes	7	7	8
98	R:R:L205	R:R:Y118	3.52	No	Yes	0	5	8
99	R:R:V206	R:R:Y118	2.52	No	Yes	0	9	8
100	R:R:F126	R:R:L119	2.44	No	No	0	5	6
101	R:R:A120	R:R:Y127	5.34	No	No	0	9	8
102	R:R:I121	R:R:N122	2.83	No	No	0	9	7
103	R:R:H123	R:R:N122	5.1	No	No	7	7	7
104	R:R:F126	R:R:Y130	8.25	No	No	0	5	5
105	R:R:V131	R:R:Y127	7.57	No	No	0	7	8
106	R:R:H129	R:R:S128	6.97	No	No	0	5	6
107	R:R:L135	R:R:L138	8.3	No	No	0	5	4
108	R:R:V143	R:R:Y144	2.52	No	No	0	7	8
109	R:R:F150	R:R:M187	7.46	No	No	0	7	5
110	R:R:L153	R:R:P154	3.28	No	No	0	8	9
111	R:R:P154	R:R:Y184	11.13	No	No	0	9	8
112	R:R:M156	R:R:N155	2.8	No	No	0	5	5
113	R:R:D173	R:R:R162	17.87	No	No	2	5	4
114	R:R:R162	R:R:T175	5.17	No	No	2	4	4
115	R:R:R162	R:R:T176	9.06	No	No	2	4	4
116	R:R:D167	R:R:L163	8.14	No	Yes	0	5	4
117	R:R:C170	R:R:L163	4.76	No	Yes	0	9	4
118	R:R:P166	R:R:Q164	12.63	Yes	Yes	1	6	7
119	R:R:Q164	R:R:T168	11.34	Yes	Yes	1	7	6
120	R:R:Q164	R:R:W169	37.24	Yes	Yes	1	7	5
121	R:R:P166	R:R:Y165	2.78	Yes	No	0	6	3
122	R:R:L302	R:R:Y165	8.21	No	No	0	1	3
123	R:R:R304	R:R:Y165	10.29	No	No	0	1	3
124	R:R:P166	R:R:T168	8.74	Yes	Yes	1	6	6
125	R:R:L312	R:R:P166	3.28	No	Yes	0	6	6
126	R:R:T168	R:R:W169	6.06	Yes	Yes	1	6	5
127	R:R:W169	R:R:W174	4.69	Yes	Yes	1	5	5
128	R:R:F171	R:R:I172	5.02	No	No	0	6	7
129	R:R:I172	R:R:Y184	12.09	No	No	0	7	8
130	R:R:D173	R:R:T175	10.12	No	No	2	5	4
131	R:R:D173	R:R:T176	11.56	No	No	2	5	4
132	R:R:V292	R:R:W174	6.13	No	Yes	0	7	5
133	R:R:N295	R:R:W174	13.56	No	Yes	1	6	5
134	R:R:D311	R:R:W174	6.7	Yes	Yes	1	6	5
135	R:R:A183	R:R:Y186	6.67	No	Yes	0	5	5
136	R:R:Q296	R:R:S185	10.11	No	No	0	6	7
137	R:R:F293	R:R:Y186	4.13	No	Yes	0	6	5
138	R:R:Q296	R:R:Y186	4.51	No	Yes	0	6	5
139	R:R:L297	R:R:Y186	4.69	No	Yes	0	4	5
140	R:R:A189	R:R:F293	4.16	Yes	No	0	7	6
141	R:R:G190	R:R:S193	3.71	No	No	0	5	6
142	R:R:F191	R:R:L195	2.44	No	No	0	6	8
143	R:R:S192	R:R:V289	6.46	No	No	0	7	7
144	R:R:F194	R:R:L195	2.44	No	No	0	4	8
145	R:R:I196	R:R:S285	3.1	Yes	No	6	7	8
146	R:R:S278	R:R:V200	4.85	No	No	0	8	6
147	R:R:L274	R:R:N203	8.24	No	Yes	0	8	9
148	R:R:N203	R:R:T277	2.92	Yes	No	0	9	8
149	R:R:N203	R:R:S278	7.45	Yes	No	0	9	8
150	R:R:C207	R:R:V204	3.42	No	No	0	7	4
151	R:R:C207	R:R:V271	3.42	No	No	0	7	7
152	R:R:G208	R:R:L211	5.13	No	No	0	3	6
153	R:R:E267	R:R:L210	3.98	No	No	0	8	9
154	R:R:E267	R:R:M213	2.71	No	No	0	8	7
155	R:R:E267	R:R:H214	11.08	No	No	0	8	5
156	R:R:H214	R:R:I268	10.61	No	No	0	5	6
157	R:R:F217	R:R:M218	7.46	No	No	0	9	8
158	R:R:M270	R:R:Q269	4.08	No	No	0	9	8
159	R:R:I272	R:R:Q269	4.12	No	No	0	7	8
160	R:R:I275	R:R:V271	3.07	No	No	0	7	7
161	R:R:I328	R:R:L273	2.85	Yes	No	8	8	8
162	R:R:L273	R:R:L332	2.77	No	No	8	8	8
163	R:R:I328	R:R:T277	3.04	Yes	No	0	8	8
164	R:R:I286	R:R:L282	5.71	No	No	0	7	6
165	R:R:C284	R:R:I283	3.27	No	No	0	9	7
166	R:R:C284	R:R:N321	3.15	No	No	0	9	9
167	R:R:I286	R:R:P287	5.08	No	No	0	7	9
168	R:R:I317	R:R:P287	5.08	No	No	0	8	9
169	R:R:A314	R:R:L288	3.15	No	No	0	7	7
170	R:R:A318	R:R:L288	4.73	No	No	0	8	7
171	R:R:A314	R:R:R291	2.77	No	No	0	7	6
172	R:R:N295	R:R:V294	2.96	No	No	0	6	5
173	R:R:D311	R:R:N295	5.39	Yes	No	1	6	6
174	R:R:Q299	R:R:Y298	3.38	No	No	0	2	4
175	R:R:Q299	R:R:S301	5.78	No	No	0	2	2
176	R:R:L302	R:R:P300	3.28	No	No	0	1	1
177	R:R:L302	R:R:P310	4.93	No	Yes	0	1	4
178	R:R:E303	R:R:E305	3.81	No	No	0	3	1
179	R:R:E303	R:R:P310	3.14	No	Yes	0	3	4
180	R:R:N309	R:R:V306	4.43	No	No	0	2	3
181	R:R:N309	R:R:P310	3.26	No	Yes	0	2	4
182	R:R:L312	R:R:N309	20.6	No	No	0	6	2
183	R:R:D311	R:R:P310	4.83	Yes	Yes	0	6	4
184	R:R:D311	R:R:L312	4.07	Yes	No	0	6	6
185	R:R:I315	R:R:S319	7.74	No	No	1	6	8
186	R:R:R316	R:R:V320	6.54	Yes	No	1	7	5
187	R:R:I323	R:R:V320	4.61	No	No	1	8	5
188	R:R:L324	R:R:V320	4.47	No	No	1	7	5
189	R:R:N321	R:R:P322	6.52	No	Yes	0	9	9
190	R:R:D325	R:R:N321	4.04	No	No	0	9	9
191	R:R:I323	R:R:L324	7.14	No	No	1	8	7
192	R:R:L331	R:R:W327	10.25	No	No	0	6	7
193	R:R:I328	R:R:Y329	2.42	Yes	Yes	0	8	9
194	R:R:I328	R:R:L332	11.42	Yes	No	8	8	8
195	R:R:R333	R:R:T335	7.76	No	No	0	9	7
196	R:R:T335	R:R:V336	3.17	No	No	0	7	7
197	R:R:L337	R:R:V336	2.98	No	No	0	7	7
198	R:R:L119	R:R:Y118	2.34	No	Yes	0	6	8
199	R:R:L140	R:R:Y144	2.34	No	No	0	8	8
200	R:R:L288	R:R:Y188	2.34	No	No	0	7	7
201	R:R:F217	R:R:H214	2.26	No	No	0	9	5
202	R:R:H129	R:R:Y130	2.18	No	No	0	5	5
203	R:R:G106	R:R:P322	2.03	No	Yes	0	9	9
204	R:R:A136	R:R:G137	1.95	No	No	0	8	5
205	R:R:A189	R:R:G190	1.95	Yes	No	0	7	5
206	R:R:A38	R:R:P326	1.87	No	No	0	9	9
207	R:R:G34	R:R:V33	1.84	No	No	0	9	5
208	R:R:G60	R:R:V63	1.84	No	No	0	8	5
209	R:R:G31	R:R:T69	1.82	No	Yes	0	8	8
210	R:R:A198	R:R:C111	1.81	No	No	0	6	7
211	R:R:P300	R:R:T175	1.75	No	No	0	1	4
212	R:R:C202	R:R:S114	1.72	No	Yes	0	7	9
213	R:R:G68	R:R:L67	1.71	No	No	0	8	7
214	R:R:C284	R:R:V280	1.71	No	No	0	9	6
215	R:R:A189	R:R:V289	1.7	Yes	No	0	7	7
216	R:R:A189	R:R:V292	1.7	Yes	No	0	7	7
217	R:R:C43	R:R:I39	1.64	No	Yes	0	4	8
218	R:R:S103	R:R:S319	1.63	No	No	0	7	8
219	R:R:A62	R:R:I39	1.62	No	Yes	0	8	8
220	R:R:S95	R:R:V72	1.62	No	Yes	0	6	7
221	R:R:A209	R:R:I121	1.62	No	No	0	7	9
222	R:R:A318	R:R:I317	1.62	No	No	0	8	8
223	R:R:V37	R:R:V41	1.6	No	No	0	6	7
224	R:R:V336	R:R:V41	1.6	No	No	0	7	7
225	R:R:V290	R:R:V294	1.6	No	No	0	7	5
226	R:R:C59	R:R:L42	1.59	No	Yes	0	6	8
227	R:R:T53	R:R:V131	1.59	No	No	0	6	7
228	R:R:T199	R:R:V281	1.59	Yes	No	0	8	8
229	R:R:T277	R:R:V281	1.59	No	No	0	8	8
230	R:R:P90	R:R:Q89	1.58	No	Yes	0	2	2
231	R:R:A152	R:R:L153	1.58	No	No	0	6	8
232	R:R:P300	R:R:Q299	1.58	No	No	0	1	2
233	R:R:I196	R:R:V200	1.54	Yes	No	0	7	6
234	R:R:I196	R:R:V281	1.54	Yes	No	0	7	8
235	R:R:F30	R:R:G31	1.51	No	No	0	5	8
236	R:R:L42	R:R:S45	1.5	Yes	No	0	8	6
237	R:R:L331	R:R:V37	1.49	No	No	0	6	6
238	R:R:L201	R:R:V204	1.49	No	No	0	4	4
239	R:R:L274	R:R:V206	1.49	No	No	0	8	9
240	R:R:L210	R:R:V271	1.49	No	No	0	9	7
241	R:R:Q49	R:R:S45	1.44	No	No	0	6	6
242	R:R:I272	R:R:L273	1.43	No	No	0	7	8
243	R:R:E93	R:R:T96	1.41	No	No	0	6	7
244	R:R:L197	R:R:L201	1.38	No	No	0	4	4
245	R:R:A209	R:R:R212	1.38	No	No	0	7	4
246	R:R:L36	R:R:N35	1.37	No	Yes	0	5	9
247	R:R:E303	R:R:K308	1.35	No	No	0	3	4
248	R:R:L163	R:R:Q164	1.33	Yes	Yes	0	4	7
249	R:R:F54	R:R:T52	1.3	No	No	0	8	7
250	R:R:S128	R:R:Y125	1.27	No	No	0	6	7
251	R:R:M218	R:R:R219	1.24	No	No	0	8	6
252	R:R:L91	R:R:Y94	1.17	No	No	0	6	5
253	R:R:Q313	R:R:R316	1.17	No	Yes	0	3	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.5675	12	1	0
2	R:R:N35	7.9025	4	3	9
3	R:R:I39	2.9425	4	3	8
4	R:R:L42	3.242	5	0	8
5	R:R:D65	4.4175	4	0	9
6	R:R:T69	3.184	5	0	8
7	R:R:V72	4.2575	4	5	7
8	R:R:Q89	4.645	4	0	2
9	R:R:L100	4.3075	4	0	7
10	R:R:F102	6.82	4	0	7
11	R:R:S114	4.6975	4	0	9
12	R:R:Y118	6.252	5	7	8
13	R:R:L163	5.22	4	0	4
14	R:R:Q164	15.635	4	1	7
15	R:R:P166	6.8575	4	1	6
16	R:R:T168	9.0175	4	1	6
17	R:R:W169	17.7525	4	1	5
18	R:R:W174	7.77	4	1	5
19	R:R:Y186	5	4	0	5
20	R:R:A189	2.3775	4	0	7
21	R:R:I196	2.2575	4	6	7
22	R:R:T199	3.1825	4	0	8
23	R:R:N203	6.1425	4	0	9
24	R:R:P310	4.04	4	0	4
25	R:R:D311	5.2475	4	1	6
26	R:R:R316	6.074	5	1	7
27	R:R:P322	5.8325	4	0	9
28	R:R:I328	4.9325	4	8	8
29	R:R:Y329	4.2675	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:T69	100	5.67	Yes	Yes	0	0	8
2	R:R:D65	R:R:T69	48.924	2.89	Yes	Yes	0	9	8
3	R:R:D65	R:R:P322	48.3248	3.22	Yes	Yes	0	9	9
4	R:R:N321	R:R:P322	96.3349	6.52	No	Yes	0	9	9
5	R:R:D325	R:R:N321	93.1992	4.04	No	No	0	9	9
6	R:R:D325	R:R:I110	92.4502	2.8	No	No	0	9	8
7	R:R:I110	R:R:Y329	43.1468	2.42	No	Yes	0	8	9
8	R:R:V58	R:R:Y329	32.7957	5.05	No	Yes	0	8	9
9	R:R:L42	R:R:V58	28.6663	2.98	Yes	No	0	8	8
10	R:R:I330	R:R:L42	14.0111	4.28	No	Yes	0	8	8
11	R:R:F102	R:R:T69	56.8233	2.59	Yes	Yes	0	7	8
12	R:R:F102	R:R:P322	52.2295	11.56	Yes	Yes	0	7	9
13	R:R:I330	R:R:V41	12.4782	7.68	No	No	0	8	7
14	R:R:F102	R:R:T64	16.7724	2.59	Yes	No	0	7	9
15	L:L:?1	R:R:T168	34.7581	9.93	Yes	Yes	1	0	6
16	R:R:Q164	R:R:T168	12.0837	11.34	Yes	Yes	1	7	6
17	R:R:L163	R:R:Q164	23.5232	1.33	Yes	Yes	0	4	7
18	R:R:L163	R:R:Q89	11.8141	6.65	Yes	Yes	0	4	2
19	L:L:?1	R:R:W169	41.2194	23.02	Yes	Yes	1	0	5
20	R:R:Q164	R:R:W169	13.302	37.24	Yes	Yes	1	7	5
21	L:L:?1	R:R:L99	20.5722	6.66	Yes	No	0	0	8
22	R:R:F171	R:R:L99	19.2091	3.65	No	No	0	6	8
23	R:R:F171	R:R:L100	15.2544	6.09	No	Yes	0	6	7
24	R:R:F191	R:R:L104	11.834	4.87	No	No	0	6	8
25	R:R:I110	R:R:T199	56.4937	4.56	No	Yes	0	8	8
26	R:R:C111	R:R:T199	13.7315	3.38	No	Yes	0	7	8
27	R:R:F191	R:R:L195	11.5544	2.44	No	No	0	6	8
28	R:R:S114	R:R:T199	52.1496	3.2	Yes	Yes	0	9	8
29	R:R:N203	R:R:S114	21.8755	5.96	Yes	Yes	0	9	9
30	R:R:R117	R:R:S114	27.3281	7.91	No	Yes	0	9	9
31	R:R:L274	R:R:N203	22.4497	8.24	No	Yes	0	8	9
32	R:R:L274	R:R:R117	19.5786	2.43	No	No	0	8	9
33	R:R:L274	R:R:V206	38.8575	1.49	No	No	0	8	9
34	R:R:V206	R:R:Y118	36.1512	2.52	No	Yes	0	9	8
35	R:R:N122	R:R:Y118	11.2798	17.44	No	Yes	7	7	8
36	R:R:L119	R:R:Y118	16.8922	2.34	No	Yes	0	6	8
37	R:R:F126	R:R:L119	14.101	2.44	No	No	0	5	6
38	R:R:F126	R:R:Y130	11.2997	8.25	No	No	0	5	5
39	R:R:P166	R:R:T168	21.7956	8.74	Yes	Yes	1	6	6
40	R:R:P166	R:R:Y165	17.5313	2.78	Yes	No	0	6	3
41	R:R:L302	R:R:Y165	14.5953	8.21	No	No	0	1	3
42	R:R:L302	R:R:P300	13.9362	3.28	No	No	0	1	1
43	R:R:W169	R:R:W174	29.4452	4.69	Yes	Yes	1	5	5
44	R:R:V292	R:R:W174	18.8096	6.13	No	Yes	0	7	5
45	R:R:A189	R:R:V292	17.2966	1.7	Yes	No	0	7	7
46	R:R:I328	R:R:Y329	12.4382	2.42	Yes	Yes	0	8	9
47	R:R:L100	R:R:Y188	11.7791	4.69	Yes	No	0	7	7
48	R:R:L288	R:R:Y188	10.5757	2.34	No	No	0	7	7
49	R:R:C111	R:R:L195	11.3047	4.76	No	No	0	7	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:I23	5.49	1	Yes	No	0	6	0	1
L:L:?1	R:R:P24	15.8	1	Yes	No	0	7	0	1
L:L:?1	R:R:M27	10.88	1	Yes	No	0	8	0	1
L:L:?1	R:R:T69	5.67	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:S73	4.34	1	Yes	No	0	8	0	1
L:L:?1	R:R:T79	8.51	1	Yes	No	0	7	0	1
L:L:?1	R:R:L99	6.66	1	Yes	No	0	8	0	1
L:L:?1	R:R:T168	9.93	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W169	23.02	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:I315	6.87	1	Yes	No	0	6	0	1
L:L:?1	R:R:S319	2.89	1	Yes	No	0	8	0	1
L:L:?1	R:R:I323	2.75	1	Yes	No	0	8	0	1
R:R:I23	R:R:P24	3.39	1	No	No	6	7	1	1
R:R:I23	R:R:R316	6.26	1	No	Yes	6	7	1	2
R:R:M27	R:R:V26	6.09	1	No	No	8	5	1	2
R:R:R316	R:R:V26	5.23	1	Yes	No	7	5	2	2
R:R:M27	R:R:R316	11.17	1	No	Yes	8	7	1	2
R:R:F28	R:R:S73	5.28	0	No	No	6	8	2	1
R:R:D65	R:R:T69	2.89	0	Yes	Yes	9	8	2	1
R:R:L70	R:R:T69	2.95	0	No	Yes	5	8	2	1
R:R:F102	R:R:T69	2.59	0	Yes	Yes	7	8	2	1
R:R:P74	R:R:S73	5.34	0	No	No	9	8	2	1
R:R:F171	R:R:L99	3.65	0	No	No	6	8	2	1
R:R:P166	R:R:Q164	12.63	1	Yes	Yes	6	7	2	2
R:R:Q164	R:R:T168	11.34	1	Yes	Yes	7	6	2	1
R:R:Q164	R:R:W169	37.24	1	Yes	Yes	7	5	2	1
R:R:P166	R:R:T168	8.74	1	Yes	Yes	6	6	2	1
R:R:T168	R:R:W169	6.06	1	Yes	Yes	6	5	1	1
R:R:W169	R:R:W174	4.69	1	Yes	Yes	5	5	1	2
R:R:I315	R:R:S319	7.74	1	No	No	6	8	1	1
R:R:R316	R:R:V320	6.54	1	Yes	No	7	5	2	2
R:R:I323	R:R:V320	4.61	1	No	No	8	5	1	2
R:R:L324	R:R:V320	4.47	1	No	No	7	5	2	2
R:R:I323	R:R:L324	7.14	1	No	No	8	7	1	2
R:R:G31	R:R:T69	1.82	0	No	Yes	8	8	2	1
R:R:S103	R:R:S319	1.63	0	No	No	7	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8GCM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.42
Number of Linked Nodes	230
Number of Links	253
Number of Hubs	29
Number of Links mediated by Hubs	106
Number of Communities	8
Number of Nodes involved in Communities	40
Number of Links involved in Communities	50

Path Summary
Number Of Nodes in MetaPath	50
Number Of Links MetaPath	49
Number of Shortest Paths	35106
Length Of Smallest Path	3
Average Path Length	12.8395
Length of Longest Path	28
Minimum Path Strength	1.435
Average Path Strength	5.40627
Maximum Path Strength	30.13
Minimum Path Correlation	0.7
Average Path Correlation	0.917793
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	47.0948
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.7621
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • prostaglandin E receptor activity • prostanoid receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • icosanoid receptor activity • prostaglandin receptor activity • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • cellular developmental process • cell development • mononuclear cell differentiation • lymphocyte activation • lymphocyte differentiation • cell activation involved in immune response • CD4-positive, alpha-beta T cell differentiation • CD4-positive, alpha-beta T cell differentiation involved in immune response • alpha-beta T cell differentiation involved in immune response • leukocyte activation • alpha-beta T cell differentiation • T cell activation involved in immune response • alpha-beta T cell activation involved in immune response • T cell activation • cell differentiation • CD4-positive, alpha-beta T cell activation • leukocyte activation involved in immune response • alpha-beta T cell activation • T cell differentiation • lymphocyte activation involved in immune response • T-helper cell differentiation • immune response • hemopoiesis • cell activation • T cell differentiation involved in immune response • immune effector process • immune system process • leukocyte differentiation • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • regulation of cytoskeleton organization • regulation of cellular component organization • regulation of actin filament-based process • regulation of actin filament bundle assembly • cellular component biogenesis • cellular component organization • cellular component assembly • actin filament bundle organization • actin filament-based process • cellular component organization or biogenesis • stress fiber assembly • regulation of actin filament organization • actin cytoskeleton organization • actomyosin structure organization • actin filament organization • regulation of cellular component biogenesis • regulation of organelle organization • regulation of stress fiber assembly • organelle organization • contractile actin filament bundle assembly • regulation of actomyosin structure organization • regulation of actin cytoskeleton organization • actin filament bundle assembly • regulation of supramolecular fiber organization • supramolecular fiber organization • cytoskeleton organization • MAPK cascade • ERK1 and ERK2 cascade • skeletal system development • bone development • negative regulation of inflammatory response • negative regulation of response to stimulus • negative regulation of biological process • negative regulation of response to external stimulus • negative regulation of defense response • ossification • regulation of multicellular organismal process • regulation of ossification • biological process involved in interspecies interaction between organisms • response to other organism • response to external biotic stimulus • response to nematode • response to biotic stimulus • negative regulation of cellular process • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • negative regulation of metabolic process • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • negative regulation of gene expression • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • response to mechanical stimulus • response to abiotic stimulus • negative regulation of locomotion • regulation of cell motility • negative regulation of eosinophil migration • eosinophil migration • eosinophil extravasation • negative regulation of cellular extravasation • cellular extravasation • myeloid leukocyte migration • regulation of cell migration • cell migration • regulation of immune system process • cell motility • negative regulation of eosinophil extravasation • negative regulation of cell migration • locomotion • regulation of leukocyte migration • regulation of eosinophil extravasation • granulocyte migration • regulation of eosinophil migration • leukocyte migration • negative regulation of leukocyte migration • negative regulation of immune system process • regulation of locomotion • negative regulation of cell motility • regulation of cellular extravasation • cellular response to mechanical stimulus • cellular response to abiotic stimulus • cellular response to external stimulus • cellular response to environmental stimulus • JNK cascade • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • positive regulation of macromolecule biosynthetic process • positive regulation of metabolic process • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • positive regulation of cellular process • positive regulation of gene expression • positive regulation of multicellular organismal process • positive regulation of cytokine production • negative regulation of cellular component organization • protein-containing complex organization • negative regulation of protein-containing complex assembly • negative regulation of integrin activation • regulation of protein-containing complex assembly • protein-containing complex assembly • regulation of integrin activation • integrin activation • response to lipopolysaccharide • response to bacterium • response to molecule of bacterial origin
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	YX9
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	YX9
Name	(5S)-5-[(3R)-4,4-difluoro-3-hydroxy-4-phenylbutyl]-1-[6-(1H-tetrazol-5-yl)hexyl]pyrrolidin-2-one
Synonyms
Identifier
Formula	C21 H29 F2 N5 O2
Molecular Weight	421.484
SMILES
PubChem	25014543
Formal Charge	0
Total Atoms	59
Total Chiral Atoms	2
Total Bonds	61
Total Aromatic Bonds	11


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35408
Sequence	>8GCM_nogp_Chain_R I P A V M F I F G V V G N L V A I V V L C K S R K E Q K E T T F Y T L V C G L A V T D L L G T L L V S P V T I A T Y M Q P L C E Y S T F I L L F F S L S G L S I I C A M S V E R Y L A I N H A Y F Y S H Y V D K R L A G L T L F A V Y A S N V L F C A L P N M R L Q Y P D T W C F I D W T T N V A Y S Y M Y A G F S S F L I L A T V L C N V L V C G A L L R M H R Q F M R G A E I Q M V I L L I A T S L V V L I C S I P L V V R V F V N Q L Y Q P S L E R E V S K N P D L Q A I R I A S V N P I L D P W I Y I L L R K T V L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8GCP	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gi1/β1/γ2	3.1	2024-01-03	10.1073/pnas.2216329120
	8GCP (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-		3.1	2024-01-03	10.1073/pnas.2216329120
	8GCM	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gi1/β1/γ2	3.5	2024-01-03	10.1073/pnas.2216329120
	8GCM (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-		3.5	2024-01-03	10.1073/pnas.2216329120
	8GDB	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gs/β1/γ2	3.1	2024-01-03	10.1073/pnas.2216329120
	8GDB (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-		3.1	2024-01-03	10.1073/pnas.2216329120
	8GDA	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gs/β1/γ2	3.3	2024-01-03	10.1073/pnas.2216329120
	8GDA (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-		3.3	2024-01-03	10.1073/pnas.2216329120
	8GD9	A	Lipid	Prostanoid	EP₄	Homo sapiens	Rivenprost	-	Gs/β1/γ2	3.2	2024-01-03	10.1073/pnas.2216329120
	8GD9 (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	Rivenprost	-		3.2	2024-01-03	10.1073/pnas.2216329120
	7D7M	A	Lipid	Prostanoid	EP₄	Homo sapiens	Dinoprostone	-	Gs/β1/γ1	3.3	2020-11-18	10.1016/j.str.2020.11.007
	7D7M (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	Dinoprostone	-		3.3	2020-11-18	10.1016/j.str.2020.11.007
	5YWY	A	Lipid	Prostanoid	EP₄	Homo sapiens	ONO-AE3-208	-	-	3.2	2018-12-05	10.1038/s41589-018-0131-3
	5YHL	A	Lipid	Prostanoid	EP₄	Homo sapiens	PubChem 135121352	-	-	4.2	2018-12-05	10.1038/s41589-018-0131-3

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8GCM_nogp.zip

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