psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:P24	12.28	Yes	No	1	0	7
2	L:L:?1	R:R:T69	6.61	Yes	No	1	0	8
3	L:L:?1	R:R:V72	5.57	Yes	No	0	0	7
4	L:L:?1	R:R:S73	5.61	Yes	Yes	1	0	8
5	L:L:?1	R:R:T76	9.92	Yes	No	1	0	8
6	L:L:?1	R:R:Y80	5.26	Yes	No	1	0	6
7	L:L:?1	R:R:L99	6.21	Yes	No	0	0	8
8	L:L:?1	R:R:S103	6.74	Yes	No	0	0	7
9	L:L:?1	R:R:T168	4.41	Yes	Yes	1	0	6
10	L:L:?1	R:R:W169	5.11	Yes	Yes	1	0	5
11	L:L:?1	R:R:L312	9.32	Yes	Yes	1	0	6
12	L:L:?1	R:R:I315	3.2	Yes	No	1	0	6
13	L:L:?1	R:R:R316	9.08	Yes	Yes	1	0	7
14	L:L:?1	R:R:S319	19.09	Yes	No	0	0	8
15	L:L:?1	R:R:P322	3.68	Yes	No	0	0	9
16	R:R:V21	R:R:Y80	17.66	No	No	0	6	6
17	R:R:T22	R:R:V26	3.17	No	No	0	5	5
18	R:R:I23	R:R:P24	3.39	No	No	0	6	7
19	R:R:I23	R:R:R316	5.01	No	Yes	0	6	7
20	R:R:P24	R:R:T76	3.5	No	No	1	7	8
21	R:R:M27	R:R:R316	3.72	No	Yes	0	8	7
22	R:R:F28	R:R:V32	6.55	Yes	No	0	6	7
23	R:R:F28	R:R:S73	15.85	Yes	Yes	0	6	8
24	R:R:F28	R:R:I77	5.02	Yes	No	0	6	6
25	R:R:G31	R:R:I323	3.53	No	No	0	8	8
26	R:R:G34	R:R:V33	3.68	No	No	0	9	5
27	R:R:D65	R:R:N35	12.12	No	Yes	0	9	9
28	R:R:L66	R:R:N35	6.87	No	Yes	0	8	9
29	R:R:N35	R:R:P326	8.15	Yes	No	0	9	9
30	R:R:L331	R:R:V37	2.98	Yes	No	0	6	6
31	R:R:A38	R:R:P326	3.74	No	No	0	9	9
32	R:R:A38	R:R:I330	3.25	No	Yes	0	9	8
33	R:R:K44	R:R:V40	3.04	No	No	0	6	5
34	R:R:L331	R:R:V41	4.47	Yes	No	0	6	7
35	R:R:L42	R:R:V58	2.98	Yes	No	4	8	8
36	R:R:C59	R:R:L42	4.76	No	Yes	0	6	8
37	R:R:I330	R:R:L42	8.56	Yes	Yes	4	8	8
38	R:R:K50	R:R:Y55	10.75	No	No	0	7	8
39	R:R:E51	R:R:T52	7.06	No	No	0	7	7
40	R:R:E116	R:R:T53	4.23	No	No	0	9	6
41	R:R:F54	R:R:V58	7.87	No	No	0	8	8
42	R:R:C59	R:R:Y55	9.41	No	No	0	6	8
43	R:R:K133	R:R:T56	9.01	No	No	0	5	6
44	R:R:A136	R:R:T56	3.36	No	No	0	8	6
45	R:R:L57	R:R:M113	7.07	No	No	0	8	9
46	R:R:E116	R:R:L57	3.98	No	No	0	9	8
47	R:R:I330	R:R:V58	9.22	Yes	No	4	8	8
48	R:R:I109	R:R:L61	7.14	No	No	0	8	9
49	R:R:D325	R:R:L61	8.14	Yes	No	0	9	9
50	R:R:T64	R:R:Y144	7.49	No	Yes	0	9	8
51	R:R:D65	R:R:P322	11.27	No	No	0	9	9
52	R:R:D325	R:R:D65	7.98	Yes	No	0	9	9
53	R:R:F102	R:R:G68	9.03	Yes	No	0	7	8
54	R:R:S73	R:R:T69	3.2	Yes	No	1	8	8
55	R:R:L71	R:R:Y94	3.52	No	No	0	6	5
56	R:R:I98	R:R:L71	5.71	Yes	No	0	5	6
57	R:R:I98	R:R:V72	9.22	Yes	No	0	5	7
58	R:R:T79	R:R:W85	8.49	No	Yes	0	7	6
59	R:R:T168	R:R:T79	3.14	Yes	No	0	6	7
60	R:R:T168	R:R:Y80	8.74	Yes	No	1	6	6
61	R:R:G83	R:R:K82	3.49	No	No	0	4	5
62	R:R:D167	R:R:Q84	10.44	No	No	0	5	4
63	R:R:L91	R:R:W85	4.56	No	Yes	0	6	6
64	R:R:C92	R:R:W85	3.92	No	Yes	3	9	6
65	R:R:L163	R:R:W85	6.83	No	Yes	0	4	6
66	R:R:C170	R:R:W85	3.92	No	Yes	3	9	6
67	R:R:P90	R:R:Q89	4.74	No	No	0	2	2
68	R:R:C170	R:R:C92	7.28	No	No	3	9	9
69	R:R:I98	R:R:S95	3.1	Yes	No	0	5	6
70	R:R:S161	R:R:T96	9.59	No	No	0	5	7
71	R:R:F102	R:R:I98	6.28	Yes	Yes	0	7	5
72	R:R:C151	R:R:L100	4.76	No	Yes	0	8	7
73	R:R:I172	R:R:L100	7.14	No	Yes	0	7	7
74	R:R:L100	R:R:Y184	3.52	Yes	Yes	0	7	8
75	R:R:L100	R:R:Y188	10.55	Yes	No	0	7	7
76	R:R:F101	R:R:F102	6.43	No	Yes	0	7	7
77	R:R:F101	R:R:Y144	5.16	No	Yes	0	7	8
78	R:R:F101	R:R:V148	3.93	No	No	0	7	4
79	R:R:L104	R:R:N147	6.87	No	No	0	8	8
80	R:R:F191	R:R:L104	6.09	No	No	0	6	8
81	R:R:S105	R:R:Y144	6.36	No	Yes	0	8	8
82	R:R:N147	R:R:S105	2.98	No	No	0	8	8
83	R:R:L107	R:R:S192	3	No	No	0	8	7
84	R:R:I196	R:R:L107	4.28	Yes	No	2	7	8
85	R:R:L107	R:R:S285	4.5	No	No	2	8	8
86	R:R:S108	R:R:V143	4.85	No	No	0	7	7
87	R:R:L195	R:R:S108	7.51	No	No	0	8	7
88	R:R:I110	R:R:T199	3.04	No	No	0	8	8
89	R:R:I110	R:R:V281	4.61	No	No	0	8	8
90	R:R:I110	R:R:Y329	3.63	No	Yes	0	8	9
91	R:R:C111	R:R:L195	3.17	No	No	0	7	8
92	R:R:C111	R:R:T199	3.38	No	No	0	7	8
93	R:R:M113	R:R:Y329	5.99	No	Yes	0	9	9
94	R:R:S114	R:R:T199	3.2	No	No	0	9	8
95	R:R:N203	R:R:S114	4.47	No	No	0	9	9
96	R:R:E116	R:R:Y127	5.61	No	Yes	0	9	8
97	R:R:L274	R:R:R117	6.07	No	No	0	8	9
98	R:R:N122	R:R:Y118	15.12	No	Yes	0	7	8
99	R:R:H123	R:R:Y118	3.27	No	Yes	0	7	8
100	R:R:L205	R:R:Y118	5.86	No	Yes	0	5	8
101	R:R:H123	R:R:L119	3.86	No	No	0	7	6
102	R:R:V131	R:R:Y127	10.09	No	Yes	0	7	8
103	R:R:H129	R:R:Y130	3.27	No	No	0	5	5
104	R:R:G137	R:R:R134	4.5	No	No	0	5	5
105	R:R:L140	R:R:Y144	3.52	No	Yes	0	8	8
106	R:R:F150	R:R:Y184	6.19	No	Yes	0	7	8
107	R:R:L153	R:R:L158	13.84	No	No	5	8	5
108	R:R:L153	R:R:Y184	4.69	No	Yes	5	8	8
109	R:R:P154	R:R:Y184	4.17	No	Yes	0	9	8
110	R:R:M156	R:R:N155	4.21	No	No	0	5	5
111	R:R:L158	R:R:Y184	7.03	No	Yes	5	5	8
112	R:R:G159	R:R:H181	7.94	No	No	0	7	5
113	R:R:D173	R:R:R162	13.1	No	No	0	5	4
114	R:R:D167	R:R:L163	9.5	No	No	0	5	4
115	R:R:Q164	R:R:W169	24.09	No	Yes	1	7	5
116	R:R:F171	R:R:Q164	3.51	Yes	No	1	6	7
117	R:R:Q164	R:R:W174	9.86	No	Yes	1	7	5
118	R:R:L302	R:R:Y165	11.72	No	No	0	1	3
119	R:R:R304	R:R:Y165	6.17	No	No	0	1	3
120	R:R:N309	R:R:Y165	3.49	No	No	0	2	3
121	R:R:P166	R:R:T168	3.5	No	Yes	1	6	6
122	R:R:P166	R:R:W169	6.76	No	Yes	1	6	5
123	R:R:L312	R:R:P166	6.57	Yes	No	1	6	6
124	R:R:T168	R:R:W169	3.64	Yes	Yes	1	6	5
125	R:R:F171	R:R:W169	3.01	Yes	Yes	1	6	5
126	R:R:I315	R:R:W169	10.57	No	Yes	1	6	5
127	R:R:F171	R:R:I172	11.3	Yes	No	0	6	7
128	R:R:F171	R:R:W174	6.01	Yes	Yes	1	6	5
129	R:R:F171	R:R:Y188	4.13	Yes	No	0	6	7
130	R:R:T175	R:R:W174	4.85	No	Yes	0	4	5
131	R:R:N295	R:R:W174	15.82	Yes	Yes	0	6	5
132	R:R:Q299	R:R:T175	5.67	No	No	0	2	4
133	R:R:T176	R:R:V178	3.17	Yes	No	0	4	3
134	R:R:H181	R:R:T176	23.28	No	Yes	0	5	4
135	R:R:A182	R:R:Q296	4.55	No	No	0	5	6
136	R:R:Q296	R:R:S185	5.78	No	No	0	6	7
137	R:R:Q296	R:R:Y186	5.64	No	No	0	6	5
138	R:R:L288	R:R:Y188	3.52	No	No	0	7	7
139	R:R:A189	R:R:F293	5.55	No	No	0	7	6
140	R:R:F191	R:R:L195	6.09	No	No	0	6	8
141	R:R:S192	R:R:V289	3.23	No	No	0	7	7
142	R:R:I196	R:R:S285	6.19	Yes	No	2	7	8
143	R:R:S278	R:R:V200	4.85	No	Yes	2	8	6
144	R:R:L282	R:R:V200	8.94	No	Yes	2	6	6
145	R:R:L274	R:R:N203	6.87	No	No	0	8	9
146	R:R:N203	R:R:S278	2.98	No	No	0	9	8
147	R:R:L210	R:R:V271	4.47	No	No	0	9	7
148	R:R:H214	R:R:M218	3.94	No	No	0	5	8
149	R:R:E267	R:R:H214	14.77	No	No	0	8	5
150	R:R:F217	R:R:Q216	3.51	No	No	0	9	9
151	R:R:I268	R:R:V271	3.07	No	No	0	6	7
152	R:R:T277	R:R:Y329	6.24	No	Yes	0	8	9
153	R:R:L282	R:R:S278	3	No	No	2	6	8
154	R:R:C284	R:R:I283	3.27	Yes	No	0	9	7
155	R:R:C284	R:R:V320	3.42	Yes	No	0	9	5
156	R:R:C284	R:R:N321	6.3	Yes	No	0	9	9
157	R:R:I286	R:R:P287	3.39	No	No	0	7	9
158	R:R:I317	R:R:P287	3.39	No	No	0	8	9
159	R:R:R291	R:R:V294	9.15	Yes	No	0	6	5
160	R:R:N295	R:R:R291	13.26	Yes	Yes	0	6	6
161	R:R:P310	R:R:R291	10.09	No	Yes	0	4	6
162	R:R:N295	R:R:P300	9.77	Yes	No	0	6	1
163	R:R:D311	R:R:N295	5.39	No	Yes	0	6	6
164	R:R:S307	R:R:V306	3.23	No	No	0	4	3
165	R:R:L312	R:R:N309	5.49	Yes	No	0	6	2
166	R:R:L312	R:R:R316	13.36	Yes	Yes	1	6	7
167	R:R:I323	R:R:V320	4.61	No	No	0	8	5
168	R:R:L324	R:R:V320	4.47	No	No	0	7	5
169	R:R:D325	R:R:P326	6.44	Yes	No	0	9	9
170	R:R:D325	R:R:Y329	3.45	Yes	Yes	0	9	9
171	R:R:L331	R:R:W327	7.97	Yes	No	0	6	7
172	R:R:I328	R:R:Y329	3.63	No	Yes	0	8	9
173	R:R:R333	R:R:V336	5.23	No	No	0	9	7
174	R:R:L273	R:R:T277	2.95	No	No	0	8	8
175	R:R:I272	R:R:I275	2.94	No	No	0	7	7
176	R:R:D173	R:R:T175	2.89	No	No	0	5	4
177	R:R:D173	R:R:T176	2.89	No	Yes	0	5	4
178	R:R:E305	R:R:S307	2.87	No	No	0	1	4
179	R:R:I39	R:R:L42	2.85	No	Yes	0	8	8
180	R:R:G88	R:R:W85	2.81	No	Yes	0	5	6
181	R:R:C151	R:R:F97	2.79	No	No	0	8	7
182	R:R:H129	R:R:S128	2.79	No	No	0	5	6
183	R:R:L331	R:R:L337	2.77	Yes	No	0	6	7
184	R:R:A120	R:R:Y127	2.67	No	Yes	0	9	8
185	R:R:A124	R:R:Y125	2.67	No	No	0	9	7
186	R:R:F293	R:R:V289	2.62	No	No	0	6	7
187	R:R:S45	R:R:Y55	2.54	No	No	0	6	8
188	R:R:V206	R:R:Y118	2.52	No	Yes	0	9	8
189	R:R:F150	R:R:M187	2.49	No	No	0	7	5
190	R:R:V75	R:R:W85	2.45	No	Yes	0	7	6
191	R:R:F28	R:R:L70	2.44	Yes	No	0	6	5
192	R:R:F102	R:R:L67	2.44	Yes	No	0	7	7
193	R:R:L119	R:R:Y127	2.34	No	Yes	0	6	8
194	R:R:H129	R:R:Y125	2.18	No	No	0	5	7
195	R:R:G87	R:R:G88	2.11	No	No	0	5	5
196	R:R:F126	R:R:Y130	2.06	No	No	0	5	5
197	R:R:C59	R:R:G60	1.96	No	No	0	6	8
198	R:R:A136	R:R:G137	1.95	No	No	0	8	5
199	R:R:A189	R:R:G190	1.95	No	No	0	7	5
200	R:R:A314	R:R:P287	1.87	No	No	0	7	9
201	R:R:G34	R:R:V37	1.84	No	No	0	9	6
202	R:R:P74	R:R:S73	1.78	No	Yes	0	9	8
203	R:R:C92	R:R:S161	1.72	No	No	3	9	5
204	R:R:C170	R:R:S161	1.72	No	No	3	9	5
205	R:R:G106	R:R:L61	1.71	No	No	0	9	9
206	R:R:C111	R:R:V115	1.71	No	No	0	7	7
207	R:R:C202	R:R:V115	1.71	No	No	0	7	7
208	R:R:G157	R:R:L158	1.71	No	No	0	8	5
209	R:R:C207	R:R:V271	1.71	No	No	0	7	7
210	R:R:G208	R:R:L211	1.71	No	No	0	3	6
211	R:R:C284	R:R:V280	1.71	Yes	No	0	9	6
212	R:R:G34	R:R:N35	1.7	No	Yes	0	9	9
213	R:R:A180	R:R:V178	1.7	No	No	0	3	3
214	R:R:A189	R:R:V292	1.7	No	No	0	7	7
215	R:R:A136	R:R:T53	1.68	No	No	0	8	6
216	R:R:A182	R:R:T176	1.68	No	Yes	0	5	4
217	R:R:N321	R:R:P322	1.63	No	No	0	9	9
218	R:R:A62	R:R:I330	1.62	No	Yes	0	8	8
219	R:R:A209	R:R:I121	1.62	No	No	0	7	9
220	R:R:S193	R:R:V289	1.62	No	No	0	6	7
221	R:R:V336	R:R:V41	1.6	No	No	0	7	7
222	R:R:V200	R:R:V204	1.6	Yes	No	0	6	4
223	R:R:V290	R:R:V294	1.6	No	No	0	7	5
224	R:R:T139	R:R:V143	1.59	No	No	0	7	7
225	R:R:T335	R:R:V336	1.59	No	No	0	7	7
226	R:R:A318	R:R:L288	1.58	No	No	0	8	7
227	R:R:A209	R:R:N122	1.56	No	No	0	7	7
228	R:R:I29	R:R:V33	1.54	No	No	0	5	5
229	R:R:I39	R:R:V63	1.54	No	No	0	8	5
230	R:R:I196	R:R:V200	1.54	Yes	Yes	2	7	6
231	R:R:I196	R:R:V281	1.54	Yes	No	0	7	8
232	R:R:L197	R:R:S193	1.5	No	No	0	4	6
233	R:R:L36	R:R:V40	1.49	No	No	0	5	5
234	R:R:I77	R:R:M81	1.46	No	No	0	6	4
235	R:R:I121	R:R:M213	1.46	No	No	0	9	7
236	R:R:Q49	R:R:S45	1.44	No	No	0	6	6
237	R:R:I39	R:R:L36	1.43	No	No	0	8	5
238	R:R:H181	R:R:S160	1.39	No	No	0	5	3
239	R:R:L279	R:R:L282	1.38	No	No	0	6	6
240	R:R:A314	R:R:R291	1.38	No	Yes	0	7	6
241	R:R:P86	R:R:W85	1.35	No	Yes	0	4	6
242	R:R:E305	R:R:K308	1.35	No	No	0	1	4
243	R:R:E267	R:R:L210	1.33	No	No	0	8	9
244	R:R:N309	R:R:Q313	1.32	No	No	0	2	3
245	R:R:R316	R:R:V306	1.31	Yes	No	0	7	3
246	R:R:F54	R:R:T52	1.3	No	No	0	8	7
247	R:R:F30	R:R:I323	1.26	No	No	0	5	8
248	R:R:F293	R:R:L297	1.22	No	No	0	6	4
249	R:R:L138	R:R:R134	1.21	No	No	0	4	5
250	R:R:F126	R:R:H123	1.13	No	No	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	7.47267	15	1	0
2	R:R:F28	7.465	4	0	6
3	R:R:N35	7.21	4	0	9
4	R:R:L42	4.7875	4	4	8
5	R:R:S73	6.61	4	1	8
6	R:R:W85	4.29125	8	3	6
7	R:R:I98	6.0775	4	0	5
8	R:R:L100	6.4925	4	0	7
9	R:R:F102	6.045	4	0	7
10	R:R:Y118	6.6925	4	0	8
11	R:R:Y127	5.1775	4	0	8
12	R:R:Y144	5.6325	4	0	8
13	R:R:T168	4.686	5	1	6
14	R:R:W169	8.86333	6	1	5
15	R:R:F171	5.592	5	1	6
16	R:R:W174	9.135	4	1	5
17	R:R:T176	7.755	4	0	4
18	R:R:Y184	5.12	5	5	8
19	R:R:I196	3.3875	4	2	7
20	R:R:V200	4.2325	4	2	6
21	R:R:C284	3.675	4	0	9
22	R:R:R291	8.47	4	0	6
23	R:R:N295	11.06	4	0	6
24	R:R:L312	8.685	4	1	6
25	R:R:R316	6.496	5	1	7
26	R:R:D325	6.5025	4	0	9
27	R:R:Y329	4.588	5	0	9
28	R:R:I330	5.6625	4	4	8
29	R:R:L331	4.5475	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:S73	10.1132	5.61	Yes	Yes	1	0	8
2	L:L:?1	R:R:P322	100	3.68	Yes	No	0	0	9
3	R:R:N321	R:R:P322	12.9564	1.63	No	No	0	9	9
4	R:R:C284	R:R:N321	11.5587	6.3	Yes	No	0	9	9
5	R:R:D65	R:R:P322	98.9212	11.27	No	No	0	9	9
6	R:R:D65	R:R:N35	31.9179	12.12	No	Yes	0	9	9
7	R:R:G34	R:R:N35	18.4248	1.7	No	Yes	0	9	9
8	R:R:N35	R:R:P326	22.7135	8.15	Yes	No	0	9	9
9	R:R:D325	R:R:D65	76.5584	7.98	Yes	No	0	9	9
10	R:R:D325	R:R:P326	28.9844	6.44	Yes	No	0	9	9
11	R:R:G34	R:R:V37	13.4506	1.84	No	No	0	9	6
12	R:R:L331	R:R:V37	11.7713	2.98	Yes	No	0	6	6
13	R:R:A38	R:R:P326	39.9798	3.74	No	No	0	9	9
14	R:R:A38	R:R:I330	37.971	3.25	No	Yes	0	9	8
15	R:R:I330	R:R:L42	25.4398	8.56	Yes	Yes	4	8	8
16	R:R:I39	R:R:L42	10.8891	2.85	No	Yes	0	8	8
17	R:R:C59	R:R:L42	13.0361	4.76	No	Yes	0	6	8
18	R:R:D325	R:R:Y329	69.772	3.45	Yes	Yes	0	9	9
19	R:R:M113	R:R:Y329	36.3661	5.99	No	Yes	0	9	9
20	R:R:L57	R:R:M113	35.3244	7.07	No	No	0	8	9
21	R:R:E116	R:R:L57	34.1234	3.98	No	No	0	9	8
22	L:L:?1	R:R:V72	20.4337	5.57	Yes	No	0	0	7
23	R:R:I98	R:R:V72	19.1476	9.22	Yes	No	0	5	7
24	R:R:F102	R:R:I98	14.0458	6.28	Yes	Yes	0	7	5
25	R:R:F101	R:R:F102	10.3417	6.43	No	Yes	0	7	7
26	L:L:?1	R:R:T168	16.9687	4.41	Yes	Yes	1	0	6
27	R:R:T168	R:R:T79	22.8676	3.14	Yes	No	0	6	7
28	R:R:T79	R:R:W85	21.5178	8.49	No	Yes	0	7	6
29	L:L:?1	R:R:W169	75.6337	5.11	Yes	Yes	1	0	5
30	R:R:F171	R:R:W169	55.7421	3.01	Yes	Yes	1	6	5
31	R:R:F171	R:R:I172	13.6047	11.3	Yes	No	0	6	7
32	R:R:I172	R:R:L100	12.3824	7.14	No	Yes	0	7	7
33	R:R:F171	R:R:Y188	16.0971	4.13	Yes	No	0	6	7
34	R:R:L100	R:R:Y188	12.5419	10.55	Yes	No	0	7	7
35	R:R:L100	R:R:Y184	17.718	3.52	Yes	Yes	0	7	8
36	R:R:I110	R:R:Y329	42.1693	3.63	No	Yes	0	8	9
37	R:R:I110	R:R:T199	20.2423	3.04	No	No	0	8	8
38	R:R:C111	R:R:T199	13.626	3.38	No	No	0	7	8
39	R:R:I110	R:R:V281	23.787	4.61	No	No	0	8	8
40	R:R:I196	R:R:V281	22.5381	1.54	Yes	No	0	7	8
41	R:R:I196	R:R:L107	13.9714	4.28	Yes	No	2	7	8
42	R:R:L107	R:R:S192	12.6694	3	No	No	0	8	7
43	R:R:E116	R:R:Y127	24.2919	5.61	No	Yes	0	9	8
44	R:R:L119	R:R:Y127	20.5718	2.34	No	Yes	0	6	8
45	R:R:H123	R:R:L119	19.2645	3.86	No	No	0	7	6
46	R:R:Q164	R:R:W169	29.6328	24.09	No	Yes	1	7	5
47	R:R:Q164	R:R:W174	28.6549	9.86	No	Yes	1	7	5
48	R:R:T175	R:R:W174	33.7727	4.85	No	Yes	0	4	5
49	R:R:D173	R:R:T175	29.0748	2.89	No	No	0	5	4
50	R:R:D173	R:R:T176	24.3344	2.89	No	Yes	0	5	4
51	R:R:F171	R:R:W174	31.8489	6.01	Yes	Yes	1	6	5
52	R:R:N295	R:R:W174	26.3219	15.82	Yes	Yes	0	6	5
53	R:R:S192	R:R:V289	11.3036	3.23	No	No	0	7	7
54	R:R:N295	R:R:R291	19.3548	13.26	Yes	Yes	0	6	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:P24	12.28	1	Yes	No	0	7	0	1
L:L:?1	R:R:T69	6.61	1	Yes	No	0	8	0	1
L:L:?1	R:R:V72	5.57	1	Yes	No	0	7	0	1
L:L:?1	R:R:S73	5.61	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:T76	9.92	1	Yes	No	0	8	0	1
L:L:?1	R:R:Y80	5.26	1	Yes	No	0	6	0	1
L:L:?1	R:R:L99	6.21	1	Yes	No	0	8	0	1
L:L:?1	R:R:S103	6.74	1	Yes	No	0	7	0	1
L:L:?1	R:R:T168	4.41	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W169	5.11	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L312	9.32	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:I315	3.2	1	Yes	No	0	6	0	1
L:L:?1	R:R:R316	9.08	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:S319	19.09	1	Yes	No	0	8	0	1
L:L:?1	R:R:P322	3.68	1	Yes	No	0	9	0	1
R:R:V21	R:R:Y80	17.66	0	No	No	6	6	2	1
R:R:I23	R:R:P24	3.39	0	No	No	6	7	2	1
R:R:I23	R:R:R316	5.01	0	No	Yes	6	7	2	1
R:R:P24	R:R:T76	3.5	1	No	No	7	8	1	1
R:R:M27	R:R:R316	3.72	0	No	Yes	8	7	2	1
R:R:F28	R:R:S73	15.85	0	Yes	Yes	6	8	2	1
R:R:D65	R:R:P322	11.27	0	No	No	9	9	2	1
R:R:S73	R:R:T69	3.2	1	Yes	No	8	8	1	1
R:R:I98	R:R:V72	9.22	0	Yes	No	5	7	2	1
R:R:T168	R:R:T79	3.14	1	Yes	No	6	7	1	2
R:R:T168	R:R:Y80	8.74	1	Yes	No	6	6	1	1
R:R:Q164	R:R:W169	24.09	1	No	Yes	7	5	2	1
R:R:F171	R:R:Q164	3.51	1	Yes	No	6	7	2	2
R:R:P166	R:R:T168	3.5	1	No	Yes	6	6	2	1
R:R:P166	R:R:W169	6.76	1	No	Yes	6	5	2	1
R:R:L312	R:R:P166	6.57	1	Yes	No	6	6	1	2
R:R:T168	R:R:W169	3.64	1	Yes	Yes	6	5	1	1
R:R:F171	R:R:W169	3.01	1	Yes	Yes	6	5	2	1
R:R:I315	R:R:W169	10.57	1	No	Yes	6	5	1	1
R:R:L312	R:R:N309	5.49	1	Yes	No	6	2	1	2
R:R:L312	R:R:R316	13.36	1	Yes	Yes	6	7	1	1
R:R:P74	R:R:S73	1.78	0	No	Yes	9	8	2	1
R:R:N321	R:R:P322	1.63	0	No	No	9	9	2	1
R:R:R316	R:R:V306	1.31	1	Yes	No	7	3	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8GCP_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.98
Number of Linked Nodes	238
Number of Links	250
Number of Hubs	29
Number of Links mediated by Hubs	121
Number of Communities	5
Number of Nodes involved in Communities	31
Number of Links involved in Communities	42

Path Summary
Number Of Nodes in MetaPath	55
Number Of Links MetaPath	54
Number of Shortest Paths	35886
Length Of Smallest Path	3
Average Path Length	12.0504
Length of Longest Path	25
Minimum Path Strength	1.46
Average Path Strength	5.89412
Maximum Path Strength	17.33
Minimum Path Correlation	0.7
Average Path Correlation	0.917022
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5
Average % Of Corr. Nodes	51.5836
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	41.6224
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation • prostaglandin E receptor activity • prostanoid receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • icosanoid receptor activity • prostaglandin receptor activity • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • cellular developmental process • cell development • mononuclear cell differentiation • lymphocyte activation • lymphocyte differentiation • cell activation involved in immune response • CD4-positive, alpha-beta T cell differentiation • CD4-positive, alpha-beta T cell differentiation involved in immune response • alpha-beta T cell differentiation involved in immune response • leukocyte activation • alpha-beta T cell differentiation • T cell activation involved in immune response • alpha-beta T cell activation involved in immune response • T cell activation • cell differentiation • CD4-positive, alpha-beta T cell activation • leukocyte activation involved in immune response • alpha-beta T cell activation • T cell differentiation • lymphocyte activation involved in immune response • T-helper cell differentiation • immune response • hemopoiesis • cell activation • T cell differentiation involved in immune response • immune effector process • immune system process • leukocyte differentiation • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • regulation of cytoskeleton organization • regulation of cellular component organization • regulation of actin filament-based process • regulation of actin filament bundle assembly • cellular component biogenesis • cellular component organization • cellular component assembly • actin filament bundle organization • actin filament-based process • cellular component organization or biogenesis • stress fiber assembly • regulation of actin filament organization • actin cytoskeleton organization • actomyosin structure organization • actin filament organization • regulation of cellular component biogenesis • regulation of organelle organization • regulation of stress fiber assembly • organelle organization • contractile actin filament bundle assembly • regulation of actomyosin structure organization • regulation of actin cytoskeleton organization • actin filament bundle assembly • regulation of supramolecular fiber organization • supramolecular fiber organization • cytoskeleton organization • MAPK cascade • ERK1 and ERK2 cascade • skeletal system development • bone development • negative regulation of inflammatory response • negative regulation of response to stimulus • negative regulation of biological process • negative regulation of response to external stimulus • negative regulation of defense response • ossification • regulation of multicellular organismal process • regulation of ossification • biological process involved in interspecies interaction between organisms • response to other organism • response to external biotic stimulus • response to nematode • response to biotic stimulus • negative regulation of cellular process • cytokine production • regulation of cytokine production • negative regulation of macromolecule metabolic process • regulation of biosynthetic process • negative regulation of metabolic process • negative regulation of cytokine production • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • negative regulation of gene expression • biosynthetic process • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • negative regulation of multicellular organismal process • regulation of metabolic process • response to mechanical stimulus • response to abiotic stimulus • negative regulation of locomotion • regulation of cell motility • negative regulation of eosinophil migration • eosinophil migration • eosinophil extravasation • negative regulation of cellular extravasation • cellular extravasation • myeloid leukocyte migration • regulation of cell migration • cell migration • regulation of immune system process • cell motility • negative regulation of eosinophil extravasation • negative regulation of cell migration • locomotion • regulation of leukocyte migration • regulation of eosinophil extravasation • granulocyte migration • regulation of eosinophil migration • leukocyte migration • negative regulation of leukocyte migration • negative regulation of immune system process • regulation of locomotion • negative regulation of cell motility • regulation of cellular extravasation • cellular response to mechanical stimulus • cellular response to abiotic stimulus • cellular response to external stimulus • cellular response to environmental stimulus • JNK cascade • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • positive regulation of macromolecule biosynthetic process • positive regulation of metabolic process • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • positive regulation of cellular process • positive regulation of gene expression • positive regulation of multicellular organismal process • positive regulation of cytokine production • negative regulation of cellular component organization • protein-containing complex organization • negative regulation of protein-containing complex assembly • negative regulation of integrin activation • regulation of protein-containing complex assembly • protein-containing complex assembly • regulation of integrin activation • integrin activation • response to lipopolysaccharide • response to bacterium • response to molecule of bacterial origin
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	P2E
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	P2E
Name	Dinoprostone
Synonyms	Dinoprostona
Identifier
Formula	C20 H32 O5
Molecular Weight	352.465
SMILES
PubChem	5280360
Formal Charge	0
Total Atoms	57
Total Chiral Atoms	4
Total Bonds	57
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35408
Sequence	>8GCP_nogp_Chain_R P V T I P A V M F I F G V V G N L V A I V V L C K S Q K E T T F Y T L V C G L A V T D L L G T L L V S P V T I A T Y M K G Q W P G G Q P L C E Y S T F I L L F F S L S G L S I I C A M S V E R Y L A I N H A Y F Y S H Y V D K R L A G L T L F A V Y A S N V L F C A L P N M G L G S S R L Q Y P D T W C F I D W T T N V T A H A A Y S Y M Y A G F S S F L I L A T V L C N V L V C G A L L R M H R Q F M R R A E I Q M V I L L I A T S L V V L I C S I P L V V R V F V N Q L Y Q P S L E R E V S K N P D L Q A I R I A S V N P I L D P W I Y I L L R K T V L S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8GCP	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gi1/β1/γ2	3.1	2024-01-03	10.1073/pnas.2216329120
	8GCP (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-		3.1	2024-01-03	10.1073/pnas.2216329120
	8GCM	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gi1/β1/γ2	3.5	2024-01-03	10.1073/pnas.2216329120
	8GCM (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-		3.5	2024-01-03	10.1073/pnas.2216329120
	8GDB	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gs/β1/γ2	3.1	2024-01-03	10.1073/pnas.2216329120
	8GDB (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-		3.1	2024-01-03	10.1073/pnas.2216329120
	8GDA	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gs/β1/γ2	3.3	2024-01-03	10.1073/pnas.2216329120
	8GDA (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-		3.3	2024-01-03	10.1073/pnas.2216329120
	8GD9	A	Lipid	Prostanoid	EP₄	Homo sapiens	Rivenprost	-	Gs/β1/γ2	3.2	2024-01-03	10.1073/pnas.2216329120
	8GD9 (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	Rivenprost	-		3.2	2024-01-03	10.1073/pnas.2216329120
	7D7M	A	Lipid	Prostanoid	EP₄	Homo sapiens	Dinoprostone	-	Gs/β1/γ1	3.3	2020-11-18	10.1016/j.str.2020.11.007
	7D7M (No Gprot)	A	Lipid	Prostanoid	EP₄	Homo sapiens	Dinoprostone	-		3.3	2020-11-18	10.1016/j.str.2020.11.007
	5YWY	A	Lipid	Prostanoid	EP₄	Homo sapiens	ONO-AE3-208	-	-	3.2	2018-12-05	10.1038/s41589-018-0131-3
	5YHL	A	Lipid	Prostanoid	EP₄	Homo sapiens	PubChem 135121352	-	-	4.2	2018-12-05	10.1038/s41589-018-0131-3

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