psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F123	20.72	Yes	Yes	1	0	5
2	L:L:?1	R:R:Y127	4.43	Yes	No	0	0	8
3	L:L:?1	R:R:H174	12.96	Yes	Yes	1	0	6
4	L:L:?1	R:R:V177	2.82	Yes	No	1	0	5
5	L:L:?1	R:R:L190	6.98	Yes	Yes	1	0	4
6	L:L:?1	R:R:Y200	19.94	Yes	Yes	1	0	5
7	L:L:?1	R:R:R203	10.72	Yes	Yes	1	0	5
8	L:L:?1	R:R:Y258	2.95	Yes	Yes	1	0	7
9	L:L:?1	R:R:K265	9.77	Yes	No	0	0	5
10	L:L:?1	R:R:L286	6.1	Yes	No	0	0	4
11	R:R:E39	R:R:S37	2.87	No	No	0	3	5
12	R:R:F38	R:R:Q105	4.68	No	Yes	0	2	4
13	R:R:F38	R:R:Y287	9.28	No	Yes	0	2	4
14	R:R:E39	R:R:Q105	3.82	No	Yes	0	3	4
15	R:R:E40	R:R:S41	5.75	No	No	0	3	4
16	R:R:R42	R:R:V46	6.54	No	No	0	4	6
17	R:R:N104	R:R:R42	3.62	No	No	0	4	4
18	R:R:Q105	R:R:R42	3.5	Yes	No	0	4	4
19	R:R:I43	R:R:R103	5.01	No	No	0	4	4
20	R:R:L45	R:R:Y49	5.86	No	Yes	0	6	8
21	R:R:L45	R:R:V291	2.98	No	No	0	6	4
22	R:R:C295	R:R:L45	3.17	No	No	0	5	6
23	R:R:V46	R:R:V99	8.02	No	No	0	6	7
24	R:R:S50	R:R:V47	3.23	No	No	0	5	5
25	R:R:L95	R:R:Y49	3.52	No	Yes	0	8	8
26	R:R:L294	R:R:Y49	5.86	No	Yes	0	6	8
27	R:R:T298	R:R:Y49	12.48	No	Yes	0	7	8
28	R:R:C53	R:R:P96	11.3	No	No	0	6	9
29	R:R:P58	R:R:V57	5.3	No	No	0	4	6
30	R:R:L89	R:R:V57	5.96	Yes	No	0	7	6
31	R:R:E88	R:R:N60	2.63	No	No	3	9	9
32	R:R:L89	R:R:N60	9.61	Yes	No	0	7	9
33	R:R:N60	R:R:P305	16.29	No	Yes	3	9	9
34	R:R:L62	R:R:L66	2.77	No	No	0	5	6
35	R:R:P305	R:R:T63	5.25	Yes	No	0	9	8
36	R:R:T63	R:R:Y308	3.75	No	No	0	8	9
37	R:R:L68	R:R:W65	3.42	No	No	0	3	3
38	R:R:I322	R:R:L66	2.85	No	No	0	4	6
39	R:R:A67	R:R:L82	4.73	No	No	0	6	5
40	R:R:L69	R:R:R321	8.5	No	Yes	0	4	5
41	R:R:A78	R:R:Q70	3.03	No	No	0	6	4
42	R:R:L82	R:R:V71	2.98	No	No	0	5	5
43	R:R:V76	R:R:Y80	3.79	No	Yes	0	6	7
44	R:R:R154	R:R:V76	10.46	No	No	0	7	6
45	R:R:I136	R:R:L77	2.85	No	No	0	8	7
46	R:R:C135	R:R:Y80	4.03	No	Yes	0	6	7
47	R:R:I136	R:R:Y80	4.84	No	Yes	0	8	7
48	R:R:A159	R:R:Y80	2.67	No	Yes	0	7	7
49	R:R:L81	R:R:Y308	9.38	No	No	0	7	9
50	R:R:F132	R:R:L84	2.44	Yes	No	0	7	9
51	R:R:D304	R:R:L84	6.79	No	No	0	9	9
52	R:R:C87	R:R:V128	3.42	No	No	0	8	7
53	R:R:E88	R:R:P305	4.72	No	Yes	3	9	9
54	R:R:L89	R:R:T92	2.95	Yes	No	0	7	6
55	R:R:T94	R:R:Y91	2.5	No	Yes	2	6	7
56	R:R:L95	R:R:Y91	11.72	No	Yes	0	8	7
57	R:R:W98	R:R:Y91	7.72	Yes	Yes	2	6	7
58	R:R:T118	R:R:Y91	4.99	No	Yes	2	5	7
59	R:R:I121	R:R:Y91	4.84	No	Yes	0	4	7
60	R:R:F122	R:R:Y91	17.54	Yes	Yes	0	6	7
61	R:R:T94	R:R:W98	9.7	No	Yes	2	6	6
62	R:R:L95	R:R:P96	4.93	No	No	0	8	9
63	R:R:L97	R:R:Y101	4.69	No	No	0	6	5
64	R:R:T118	R:R:W98	16.98	No	Yes	2	5	6
65	R:R:I100	R:R:R103	3.76	No	No	0	3	4
66	R:R:I102	R:R:R107	5.01	No	No	0	6	5
67	R:R:H106	R:R:N104	2.55	No	No	0	5	4
68	R:R:Q105	R:R:R107	10.51	Yes	No	0	4	5
69	R:R:F187	R:R:H106	32.81	Yes	No	4	4	5
70	R:R:D188	R:R:H106	2.52	No	No	4	5	5
71	R:R:L112	R:R:W108	9.11	No	No	0	3	9
72	R:R:C115	R:R:W108	9.14	No	No	0	9	9
73	R:R:F187	R:R:W108	7.02	Yes	No	0	4	9
74	R:R:L110	R:R:T109	2.95	No	No	0	6	4
75	R:R:K116	R:R:L112	5.64	No	No	0	8	3
76	R:R:C115	R:R:K116	3.23	No	No	0	9	8
77	R:R:E181	R:R:K116	2.7	No	No	0	5	8
78	R:R:I121	R:R:V117	3.07	No	No	0	4	4
79	R:R:A119	R:R:F123	2.77	No	Yes	0	6	5
80	R:R:F167	R:R:Y120	6.19	No	No	0	9	5
81	R:R:I121	R:R:N125	4.25	No	No	0	4	9
82	R:R:F122	R:R:F123	7.5	Yes	Yes	0	6	5
83	R:R:F122	R:R:I126	5.02	Yes	No	0	6	7
84	R:R:F122	R:R:L294	3.65	Yes	No	0	6	6
85	R:R:F123	R:R:H174	5.66	Yes	Yes	1	5	6
86	R:R:C124	R:R:N125	3.15	No	No	0	5	9
87	R:R:C124	R:R:F167	2.79	No	No	0	5	9
88	R:R:V170	R:R:Y127	5.05	No	No	0	7	8
89	R:R:F208	R:R:Y127	8.25	Yes	No	0	8	8
90	R:R:F132	R:R:V128	2.62	Yes	No	0	7	7
91	R:R:F208	R:R:I130	2.51	Yes	Yes	1	8	7
92	R:R:F251	R:R:I130	2.51	No	Yes	1	9	7
93	R:R:F255	R:R:I130	2.51	Yes	Yes	1	9	7
94	R:R:I166	R:R:L131	9.99	No	No	0	6	5
95	R:R:C135	R:R:F132	2.79	No	Yes	0	6	7
96	R:R:F132	R:R:S163	2.64	Yes	No	0	7	6
97	R:R:F132	R:R:I166	2.51	Yes	No	0	7	6
98	R:R:C134	R:R:P211	3.77	No	No	0	7	9
99	R:R:C134	R:R:I215	4.91	No	No	0	7	8
100	R:R:I215	R:R:S137	3.1	No	No	0	8	9
101	R:R:S137	R:R:T218	3.2	No	No	0	9	6
102	R:R:F141	R:R:V145	5.24	No	No	5	8	7
103	R:R:F141	R:R:Y146	4.13	No	No	5	8	6
104	R:R:F141	R:R:T218	3.89	No	No	0	8	6
105	R:R:V142	R:R:Y146	3.79	No	No	0	5	6
106	R:R:S150	R:R:V142	4.85	No	No	0	6	5
107	R:R:I222	R:R:V144	4.61	No	No	0	8	8
108	R:R:S225	R:R:V144	3.23	No	No	0	4	8
109	R:R:V145	R:R:Y146	3.79	No	No	5	7	6
110	R:R:E149	R:R:R153	8.14	No	No	0	4	4
111	R:R:G152	R:R:R153	4.5	No	No	0	4	4
112	R:R:R155	R:R:R157	6.4	No	No	0	6	4
113	R:R:R155	R:R:T158	7.76	No	No	0	6	2
114	R:R:R156	R:R:R157	10.66	No	No	0	3	4
115	R:R:I162	R:R:I166	2.94	No	No	0	4	6
116	R:R:H174	R:R:V170	2.77	Yes	No	0	6	7
117	R:R:R203	R:R:V173	3.92	Yes	No	0	5	5
118	R:R:H174	R:R:V177	4.15	Yes	No	1	6	5
119	R:R:P176	R:R:Y175	4.17	No	No	0	8	4
120	R:R:Q179	R:R:Y175	15.78	No	No	0	4	4
121	R:R:R203	R:R:V177	6.54	Yes	No	1	5	5
122	R:R:F178	R:R:Q179	8.2	No	No	0	4	4
123	R:R:D182	R:R:E184	6.5	No	No	0	5	4
124	R:R:F187	R:R:T185	6.49	Yes	No	0	4	3
125	R:R:D188	R:R:F187	5.97	No	Yes	4	5	4
126	R:R:D188	R:R:Y287	10.34	No	Yes	0	5	4
127	R:R:M189	R:R:Q191	2.72	No	No	0	4	4
128	R:R:F269	R:R:L190	4.87	Yes	Yes	1	4	4
129	R:R:D275	R:R:L190	4.07	No	Yes	1	2	4
130	R:R:E283	R:R:L190	13.25	No	Yes	0	3	4
131	R:R:Q191	R:R:S194	4.33	No	No	0	4	1
132	R:R:M192	R:R:Y272	9.58	No	No	0	3	1
133	R:R:D193	R:R:R195	16.68	No	No	0	1	3
134	R:R:A197	R:R:S194	3.42	No	No	0	4	1
135	R:R:F269	R:R:S194	10.57	Yes	No	0	4	1
136	R:R:R195	R:R:Y199	8.23	No	No	0	3	4
137	R:R:A197	R:R:K265	3.21	No	No	0	4	5
138	R:R:R203	R:R:Y199	5.14	Yes	No	0	5	4
139	R:R:R203	R:R:Y200	5.14	Yes	Yes	1	5	5
140	R:R:Y200	R:R:Y258	3.97	Yes	Yes	1	5	7
141	R:R:L262	R:R:Y200	14.07	No	Yes	1	6	5
142	R:R:F204	R:R:Y201	3.09	Yes	No	0	5	4
143	R:R:T205	R:R:Y201	7.49	No	No	0	4	4
144	R:R:F204	R:R:F208	8.57	Yes	Yes	1	5	8
145	R:R:F204	R:R:H259	5.66	Yes	No	1	5	8
146	R:R:F204	R:R:L263	6.09	Yes	No	0	5	5
147	R:R:F208	R:R:H259	31.68	Yes	No	1	8	8
148	R:R:I210	R:R:P211	3.39	No	No	0	5	9
149	R:R:I210	R:R:S213	3.1	No	No	0	5	2
150	R:R:I214	R:R:S213	3.1	No	No	0	6	2
151	R:R:I215	R:R:V248	3.07	No	No	0	8	6
152	R:R:A216	R:R:H220	2.93	No	No	0	4	4
153	R:R:F217	R:R:R221	7.48	No	No	0	4	4
154	R:R:I222	R:R:N219	2.83	No	Yes	0	8	9
155	R:R:F223	R:R:N219	9.67	No	Yes	0	4	9
156	R:R:A244	R:R:N219	4.69	No	Yes	0	6	9
157	R:R:N219	R:R:V248	2.96	Yes	No	0	9	6
158	R:R:H220	R:R:R221	4.51	No	No	0	4	4
159	R:R:R221	R:R:R224	11.73	No	No	0	4	4
160	R:R:I222	R:R:K241	2.91	No	Yes	0	8	5
161	R:R:F223	R:R:K241	11.17	No	Yes	0	4	5
162	R:R:K227	R:R:R224	4.95	No	No	0	4	4
163	R:R:I226	R:R:S229	3.1	No	No	0	8	5
164	R:R:I226	R:R:K237	4.36	No	No	0	8	6
165	R:R:I226	R:R:K241	8.72	No	Yes	0	8	5
166	R:R:A234	R:R:K237	3.21	No	No	0	4	6
167	R:R:K239	R:R:Q236	5.42	No	No	0	7	5
168	R:R:A238	R:R:H242	2.93	No	No	0	4	5
169	R:R:D313	R:R:K239	13.83	No	No	0	5	7
170	R:R:K241	R:R:V240	3.04	Yes	No	0	5	7
171	R:R:L252	R:R:V248	2.98	No	No	0	5	6
172	R:R:I250	R:R:N300	5.66	No	Yes	0	6	9
173	R:R:I250	R:R:I307	2.94	No	No	0	6	7
174	R:R:F251	R:R:L252	2.44	No	No	0	9	5
175	R:R:F251	R:R:F255	6.43	No	Yes	1	9	9
176	R:R:C254	R:R:F255	2.79	No	Yes	1	8	9
177	R:R:C254	R:R:N300	12.6	No	Yes	1	8	9
178	R:R:F255	R:R:S297	2.64	Yes	No	0	9	8
179	R:R:F255	R:R:N300	12.08	Yes	Yes	1	9	9
180	R:R:F293	R:R:P257	4.33	Yes	No	0	7	9
181	R:R:L262	R:R:Y258	15.24	No	Yes	1	6	7
182	R:R:F293	R:R:Y258	5.16	Yes	Yes	0	7	7
183	R:R:H259	R:R:L262	2.57	No	No	1	8	6
184	R:R:F293	R:R:V261	6.55	Yes	No	0	7	5
185	R:R:F269	R:R:K265	8.69	Yes	No	0	4	5
186	R:R:A267	R:R:Y271	5.34	No	No	0	4	2
187	R:R:D275	R:R:F269	8.36	No	Yes	1	2	4
188	R:R:S270	R:R:Y271	7.63	No	No	0	3	2
189	R:R:R273	R:R:Y271	13.38	No	No	0	1	2
190	R:R:D275	R:R:Y272	8.05	No	No	0	2	1
191	R:R:M279	R:R:R276	7.44	No	No	0	4	6
192	R:R:L282	R:R:R276	4.86	No	No	0	1	6
193	R:R:A278	R:R:M279	3.22	No	No	0	1	4
194	R:R:C280	R:R:E283	6.08	No	No	0	8	3
195	R:R:E284	R:R:G281	3.27	No	No	0	4	2
196	R:R:L282	R:R:L286	2.77	No	No	0	1	4
197	R:R:E284	R:R:T288	2.82	No	No	0	4	2
198	R:R:L286	R:R:R285	8.5	No	No	0	4	2
199	R:R:S290	R:R:Y287	3.82	No	Yes	0	5	4
200	R:R:V291	R:R:Y287	5.05	No	Yes	0	4	4
201	R:R:A289	R:R:F293	2.77	No	Yes	0	6	7
202	R:R:F293	R:R:L296	4.87	Yes	No	0	7	8
203	R:R:L294	R:R:S297	4.5	No	No	0	6	8
204	R:R:D304	R:R:P305	3.22	No	Yes	0	9	9
205	R:R:V309	R:R:Y308	3.79	No	No	0	6	9
206	R:R:S315	R:R:V309	3.23	No	No	0	7	6
207	R:R:D313	R:R:R316	3.57	No	No	0	5	8
208	R:R:E318	R:R:R321	16.28	No	Yes	0	4	5
209	R:R:H323	R:R:V319	4.15	No	No	0	3	5
210	R:R:I322	R:R:R321	7.52	No	Yes	0	4	5
211	R:R:E328	R:R:G325	3.27	No	No	0	3	4
212	R:R:K327	R:R:W326	3.48	No	No	0	2	1
213	R:R:S330	R:R:W326	2.47	No	No	6	5	1
214	R:R:K332	R:R:W326	4.64	No	No	6	4	1
215	R:R:K332	R:R:S330	6.12	No	No	6	4	5
216	R:R:D334	R:R:R337	19.06	No	No	0	5	6
217	R:R:T336	R:R:T339	3.14	No	No	7	6	5
218	R:R:H340	R:R:T336	4.11	No	No	7	7	6
219	R:R:L338	R:R:S341	3	No	No	0	4	7
220	R:R:H340	R:R:T339	4.11	No	No	7	7	5
221	R:R:R342	R:R:T339	6.47	No	No	0	8	5
222	R:R:F223	R:R:H220	2.26	No	No	0	4	4
223	R:R:G56	R:R:P58	2.03	No	No	0	8	4
224	R:R:G93	R:R:P96	2.03	No	No	0	4	9
225	R:R:A78	R:R:G74	1.95	No	No	0	6	5
226	R:R:A268	R:R:G274	1.95	No	No	0	3	3
227	R:R:W98	R:R:Y101	1.93	Yes	No	0	6	5
228	R:R:A256	R:R:P257	1.87	No	No	0	4	9
229	R:R:G56	R:R:V302	1.84	No	No	0	8	7
230	R:R:G207	R:R:V206	1.84	No	No	0	6	4
231	R:R:A64	R:R:A85	1.79	No	No	0	7	8
232	R:R:G325	R:R:K324	1.74	No	No	0	4	6
233	R:R:C53	R:R:V57	1.71	No	No	0	6	6
234	R:R:G93	R:R:L89	1.71	No	Yes	0	4	7
235	R:R:G111	R:R:L110	1.71	No	No	0	8	6
236	R:R:G111	R:R:L113	1.71	No	No	0	8	1
237	R:R:A143	R:R:S150	1.71	No	No	0	8	6
238	R:R:A244	R:R:S243	1.71	No	No	0	6	7
239	R:R:A311	R:R:S243	1.71	No	No	0	5	7
240	R:R:G274	R:R:L282	1.71	No	No	0	3	1
241	R:R:A159	R:R:V79	1.7	No	No	0	7	6
242	R:R:A268	R:R:V264	1.7	No	No	0	3	4
243	R:R:A51	R:R:T54	1.68	No	No	0	5	4
244	R:R:A85	R:R:T63	1.68	No	No	0	8	8
245	R:R:C83	R:R:I160	1.64	No	No	0	9	3
246	R:R:E88	R:R:G301	1.64	No	No	0	9	7
247	R:R:S315	R:R:V319	1.62	No	No	0	7	5
248	R:R:V48	R:R:V52	1.6	No	No	0	5	7
249	R:R:V302	R:R:V52	1.6	No	No	0	7	7
250	R:R:V249	R:R:V253	1.6	No	No	0	4	5
251	R:R:S315	R:R:T312	1.6	No	No	0	7	7
252	R:R:S341	R:R:T344	1.6	No	No	0	7	8
253	R:R:C61	R:R:L89	1.59	No	Yes	0	4	7
254	R:R:C83	R:R:L82	1.59	No	No	0	9	5
255	R:R:T333	R:R:V335	1.59	No	No	0	5	4
256	R:R:T336	R:R:V335	1.59	No	No	0	6	4
257	R:R:A114	R:R:L110	1.58	No	No	0	5	6
258	R:R:A311	R:R:L310	1.58	No	No	0	5	7
259	R:R:A278	R:R:N277	1.56	No	No	0	1	2
260	R:R:A303	R:R:N300	1.56	No	Yes	0	6	9
261	R:R:I130	R:R:S129	1.55	Yes	No	0	7	9
262	R:R:I43	R:R:V44	1.54	No	No	0	4	4
263	R:R:I43	R:R:V46	1.54	No	No	0	4	6
264	R:R:I160	R:R:V79	1.54	No	No	0	3	6
265	R:R:I100	R:R:V99	1.54	No	No	0	3	7
266	R:R:I245	R:R:V249	1.54	No	No	0	4	4
267	R:R:I307	R:R:V247	1.54	No	No	0	7	8
268	R:R:I102	R:R:T109	1.52	No	No	0	6	4
269	R:R:L68	R:R:V71	1.49	No	No	0	3	5
270	R:R:L296	R:R:V292	1.49	No	No	0	8	5
271	R:R:L55	R:R:T54	1.47	No	No	0	5	4
272	R:R:D139	R:R:V76	1.46	No	No	0	8	6
273	R:R:I196	R:R:M189	1.46	No	No	0	5	4
274	R:R:G198	R:R:Y201	1.45	No	No	0	3	4
275	R:R:E149	R:R:V142	1.43	No	No	0	4	5
276	R:R:I162	R:R:L161	1.43	No	No	0	4	3
277	R:R:E184	R:R:T185	1.41	No	No	0	4	3
278	R:R:D334	R:R:M331	1.39	No	No	0	5	4
279	R:R:L133	R:R:L84	1.38	No	No	0	8	9
280	R:R:L212	R:R:L252	1.38	No	No	0	5	5
281	R:R:H314	R:R:T312	1.37	No	No	0	6	7
282	R:R:R321	R:R:S320	1.32	Yes	No	0	5	3
283	R:R:R103	R:R:V47	1.31	No	No	0	4	5
284	R:R:E39	R:R:E40	1.27	No	No	0	3	3
285	R:R:I136	R:R:R140	1.25	No	No	0	8	9
286	R:R:T180	R:R:Y199	1.25	No	No	0	4	4
287	R:R:N75	R:R:R154	1.21	No	No	0	7	7
288	R:R:E181	R:R:F178	1.17	No	No	0	5	4
289	R:R:Q317	R:R:R316	1.17	No	No	0	4	8
290	R:R:E284	R:R:R285	1.16	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	9.739	10	1	0
2	R:R:Y49	6.93	4	0	8
3	R:R:Y80	3.8325	4	0	7
4	R:R:L89	4.364	5	0	7
5	R:R:Y91	8.21833	6	2	7
6	R:R:W98	9.0825	4	2	6
7	R:R:Q105	5.6275	4	0	4
8	R:R:F122	8.4275	4	0	6
9	R:R:F123	9.1625	4	1	5
10	R:R:I130	2.27	4	1	7
11	R:R:F132	2.6	5	0	7
12	R:R:H174	6.385	4	1	6
13	R:R:F187	13.0725	4	4	4
14	R:R:L190	7.2925	4	1	4
15	R:R:Y200	10.78	4	1	5
16	R:R:R203	6.292	5	1	5
17	R:R:F204	5.8525	4	1	5
18	R:R:F208	12.7525	4	1	8
19	R:R:N219	5.0375	4	0	9
20	R:R:K241	6.46	4	0	5
21	R:R:F255	5.29	5	1	9
22	R:R:Y258	6.83	4	1	7
23	R:R:F269	8.1225	4	1	4
24	R:R:Y287	7.1225	4	0	4
25	R:R:F293	4.736	5	0	7
26	R:R:N300	7.975	4	1	9
27	R:R:P305	7.37	4	3	9
28	R:R:R321	8.405	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F123	68.1919	20.72	Yes	Yes	1	0	5
2	R:R:F122	R:R:F123	72.741	7.5	Yes	Yes	0	6	5
3	R:R:F122	R:R:L294	37.4323	3.65	Yes	No	0	6	6
4	R:R:L294	R:R:Y49	91.4171	5.86	No	Yes	0	6	8
5	R:R:L45	R:R:Y49	86.6282	5.86	No	Yes	0	6	8
6	R:R:L45	R:R:V291	83.9271	2.98	No	No	0	6	4
7	R:R:V291	R:R:Y287	82.55	5.05	No	Yes	0	4	4
8	R:R:F38	R:R:Y287	42.1857	9.28	No	Yes	0	2	4
9	R:R:F38	R:R:Q105	40.382	4.68	No	Yes	0	2	4
10	R:R:Q105	R:R:R42	19.5913	3.5	Yes	No	0	4	4
11	R:R:R42	R:R:V46	17.0502	6.54	No	No	0	4	6
12	R:R:D188	R:R:Y287	42.1857	10.34	No	Yes	0	5	4
13	R:R:I43	R:R:V46	10.7152	1.54	No	No	0	4	6
14	R:R:F122	R:R:Y91	49.809	17.54	Yes	Yes	0	6	7
15	R:R:L95	R:R:Y91	47.4633	11.72	No	Yes	0	8	7
16	R:R:L95	R:R:P96	100	4.93	No	No	0	8	9
17	R:R:C53	R:R:P96	12.5633	11.3	No	No	0	6	9
18	R:R:C53	R:R:V57	11.2306	1.71	No	No	0	6	6
19	R:R:P58	R:R:V57	11.1861	5.3	No	No	0	4	6
20	R:R:G93	R:R:P96	86.1484	2.03	No	No	0	4	9
21	R:R:G93	R:R:L89	84.8156	1.71	No	Yes	0	4	7
22	R:R:L89	R:R:N60	83.2608	9.61	Yes	No	0	7	9
23	R:R:N60	R:R:P305	77.9476	16.29	No	Yes	3	9	9
24	R:R:P305	R:R:T63	24.0338	5.25	Yes	No	0	9	8
25	R:R:T63	R:R:Y308	17.6899	3.75	No	No	0	8	9
26	R:R:D304	R:R:P305	58.7383	3.22	No	Yes	0	9	9
27	R:R:D304	R:R:L84	56.9614	6.79	No	No	0	9	9
28	R:R:F132	R:R:L84	53.3541	2.44	Yes	No	0	7	9
29	R:R:C135	R:R:F132	38.2141	2.79	No	Yes	0	6	7
30	R:R:C135	R:R:Y80	36.2417	4.03	No	Yes	0	6	7
31	R:R:A159	R:R:Y80	19.8223	2.67	No	Yes	0	7	7
32	R:R:A159	R:R:V79	17.6899	1.7	No	No	0	7	6
33	R:R:I160	R:R:V79	15.5398	1.54	No	No	0	3	6
34	R:R:C83	R:R:I160	13.3718	1.64	No	No	0	9	3
35	R:R:C83	R:R:L82	11.1861	1.59	No	No	0	9	5
36	R:R:I121	R:R:Y91	12.9987	4.84	No	Yes	0	4	7
37	R:R:Q105	R:R:R107	16.1617	10.51	Yes	No	0	4	5
38	R:R:I102	R:R:R107	13.9049	5.01	No	No	0	6	5
39	R:R:D188	R:R:F187	36.7925	5.97	No	Yes	4	5	4
40	R:R:F187	R:R:W108	32.6433	7.02	Yes	No	0	4	9
41	R:R:L112	R:R:W108	15.2999	9.11	No	No	0	3	9
42	R:R:C115	R:R:W108	15.2999	9.14	No	No	0	9	9
43	R:R:I102	R:R:T109	11.6304	1.52	No	No	0	6	4
44	R:R:K116	R:R:L112	13.1675	5.64	No	No	0	8	3
45	R:R:C115	R:R:K116	13.1675	3.23	No	No	0	9	8
46	R:R:E181	R:R:K116	21.9813	2.7	No	No	0	5	8
47	L:L:?1	R:R:Y127	36.9169	4.43	Yes	No	0	0	8
48	R:R:F208	R:R:Y127	36.6237	8.25	Yes	No	0	8	8
49	R:R:F208	R:R:I130	44.5846	2.51	Yes	Yes	1	8	7
50	R:R:F251	R:R:I130	32.7321	2.51	No	Yes	1	9	7
51	R:R:F251	R:R:L252	88.032	2.44	No	No	0	9	5
52	R:R:L252	R:R:V248	85.1	2.98	No	No	0	5	6
53	R:R:I215	R:R:V248	36.3394	3.07	No	No	0	8	6
54	R:R:C134	R:R:I215	11.2306	4.91	No	No	0	7	8
55	R:R:I215	R:R:S137	24.1315	3.1	No	No	0	8	9
56	R:R:S137	R:R:T218	22.0258	3.2	No	No	0	9	6
57	R:R:F141	R:R:T218	19.9023	3.89	No	No	0	8	6
58	R:R:F141	R:R:Y146	15.5398	4.13	No	No	5	8	6
59	R:R:V142	R:R:Y146	13.4251	3.79	No	No	0	5	6
60	R:R:N219	R:R:V248	55.4065	2.96	Yes	No	0	9	6
61	R:R:I222	R:R:N219	19.0493	2.83	No	Yes	0	8	9
62	L:L:?1	R:R:R203	12.5722	10.72	Yes	Yes	1	0	5
63	R:R:E181	R:R:F178	17.6188	1.17	No	No	0	5	4
64	R:R:F178	R:R:Q179	13.2386	8.2	No	No	0	4	4
65	L:L:?1	R:R:L190	22.3279	6.98	Yes	Yes	1	0	4
66	R:R:F269	R:R:L190	10.3332	4.87	Yes	Yes	1	4	4
67	R:R:F269	R:R:S194	16.5438	10.57	Yes	No	0	4	1
68	R:R:Q191	R:R:S194	18.5162	4.33	No	No	0	4	1
69	R:R:M189	R:R:Q191	12.359	2.72	No	No	0	4	4
70	L:L:?1	R:R:K265	22.3279	9.77	Yes	No	0	0	5
71	R:R:F269	R:R:K265	10.2799	8.69	Yes	No	0	4	5
72	R:R:A197	R:R:K265	10.2532	3.21	No	No	0	4	5
73	L:L:?1	R:R:Y258	18.7916	2.95	Yes	Yes	1	0	7
74	R:R:F204	R:R:F208	12.7854	8.57	Yes	Yes	1	5	8
75	R:R:F223	R:R:N219	27.4367	9.67	No	Yes	0	4	9
76	R:R:F223	R:R:H220	13.2652	2.26	No	No	0	4	4
77	R:R:I222	R:R:K241	12.9187	2.91	No	Yes	0	8	5
78	R:R:F223	R:R:K241	13.1319	11.17	No	Yes	0	4	5
79	R:R:I226	R:R:K241	17.1924	8.72	No	Yes	0	8	5
80	R:R:F255	R:R:I130	13.6739	2.51	Yes	Yes	1	9	7
81	R:R:F255	R:R:N300	11.1417	12.08	Yes	Yes	1	9	9
82	R:R:L294	R:R:S297	71.6748	4.5	No	No	0	6	8
83	R:R:F293	R:R:Y258	18.8983	5.16	Yes	Yes	0	7	7
84	L:L:?1	R:R:L286	27.3656	6.1	Yes	No	0	0	4
85	R:R:L282	R:R:L286	17.1924	2.77	No	No	0	1	4
86	R:R:V309	R:R:Y308	13.3718	3.79	No	No	0	6	9
87	R:R:S315	R:R:V309	11.1861	3.23	No	No	0	7	6
88	R:R:F255	R:R:S297	70.6708	2.64	Yes	No	0	9	8
89	R:R:F251	R:R:F255	56.6948	6.43	No	Yes	1	9	9
90	R:R:L95	R:R:Y49	64.6824	3.52	No	Yes	0	8	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:F123	20.72	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y127	4.43	1	Yes	No	0	8	0	1
L:L:?1	R:R:H174	12.96	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:V177	2.82	1	Yes	No	0	5	0	1
L:L:?1	R:R:L190	6.98	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:Y200	19.94	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:R203	10.72	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y258	2.95	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:K265	9.77	1	Yes	No	0	5	0	1
L:L:?1	R:R:L286	6.1	1	Yes	No	0	4	0	1
R:R:A119	R:R:F123	2.77	0	No	Yes	6	5	2	1
R:R:F122	R:R:F123	7.5	0	Yes	Yes	6	5	2	1
R:R:F123	R:R:H174	5.66	1	Yes	Yes	5	6	1	1
R:R:V170	R:R:Y127	5.05	0	No	No	7	8	2	1
R:R:F208	R:R:Y127	8.25	1	Yes	No	8	8	2	1
R:R:H174	R:R:V170	2.77	1	Yes	No	6	7	1	2
R:R:R203	R:R:V173	3.92	1	Yes	No	5	5	1	2
R:R:H174	R:R:V177	4.15	1	Yes	No	6	5	1	1
R:R:R203	R:R:V177	6.54	1	Yes	No	5	5	1	1
R:R:F269	R:R:L190	4.87	1	Yes	Yes	4	4	2	1
R:R:D275	R:R:L190	4.07	1	No	Yes	2	4	2	1
R:R:E283	R:R:L190	13.25	0	No	Yes	3	4	2	1
R:R:A197	R:R:K265	3.21	0	No	No	4	5	2	1
R:R:R203	R:R:Y199	5.14	1	Yes	No	5	4	1	2
R:R:R203	R:R:Y200	5.14	1	Yes	Yes	5	5	1	1
R:R:Y200	R:R:Y258	3.97	1	Yes	Yes	5	7	1	1
R:R:L262	R:R:Y200	14.07	1	No	Yes	6	5	2	1
R:R:L262	R:R:Y258	15.24	1	No	Yes	6	7	2	1
R:R:F293	R:R:Y258	5.16	0	Yes	Yes	7	7	2	1
R:R:F269	R:R:K265	8.69	1	Yes	No	4	5	2	1
R:R:D275	R:R:F269	8.36	1	No	Yes	2	4	2	2
R:R:L282	R:R:L286	2.77	0	No	No	1	4	2	1
R:R:L286	R:R:R285	8.5	0	No	No	4	2	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8HQN_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.44
Number of Linked Nodes	277
Number of Links	290
Number of Hubs	28
Number of Links mediated by Hubs	107
Number of Communities	7
Number of Nodes involved in Communities	38
Number of Links involved in Communities	48

Path Summary
Number Of Nodes in MetaPath	91
Number Of Links MetaPath	90
Number of Shortest Paths	31578
Length Of Smallest Path	3
Average Path Length	14.0013
Length of Longest Path	35
Minimum Path Strength	1.485
Average Path Strength	5.76397
Maximum Path Strength	20.33
Minimum Path Correlation	0.7
Average Path Correlation	0.967357
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	6.25
Average % Of Corr. Nodes	66.9057
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	34.0897
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • binding • tetrapyrrole binding • heme binding • electron transfer activity • cation binding • transition metal ion binding • iron ion binding • ion binding • metal ion binding • small molecule binding • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • electron transport chain • metabolic process • cellular process • generation of precursor metabolites and energy • mitotic cell cycle process • cell cycle phase transition • cell cycle • G1/S transition of mitotic cell cycle • cell cycle G1/S phase transition • mitotic cell cycle • mitotic cell cycle phase transition • cell cycle process • regulation of cell cycle phase transition • regulation of cellular process • G2/M transition of mitotic cell cycle • negative regulation of biological process • negative regulation of cell cycle • negative regulation of mitotic cell cycle • regulation of mitotic cell cycle • negative regulation of cellular process • negative regulation of cell cycle phase transition • regulation of cell cycle • cell cycle G2/M phase transition • regulation of biological process • negative regulation of mitotic cell cycle phase transition • regulation of G2/M transition of mitotic cell cycle • regulation of cell cycle process • biological regulation • regulation of cell cycle G2/M phase transition • negative regulation of cell cycle process • regulation of mitotic cell cycle phase transition • negative regulation of cell cycle G2/M phase transition • negative regulation of G2/M transition of mitotic cell cycle • periplasmic space • protein binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	9HO
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	9HO
Name	9(S)-HODE
Synonyms	alpha-Dimorphecolic acid 9S-Hode 9(S)-HODE (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
Identifier
Formula	C18 H32 O3
Molecular Weight	296.445
SMILES
PubChem	5312830
Formal Charge	0
Total Atoms	53
Total Chiral Atoms	1
Total Bonds	52
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9UNW8
Sequence	>8HQN_nogp_Chain_R S F E E S R I V L V V V Y S A V C T L G V P A N C L T A W L A L L Q V L Q G N V L A V Y L L C L A L C E L L Y T G T L P L W V I Y I R N Q H R W T L G L L A C K V T A Y I F F C N I Y V S I L F L C C I S C D R F V A V V Y A L E S R G R R R R R T A I L I S A C I F I L V G I V H Y P V F Q T E D K E T C F D M L Q M D S R I A G Y Y Y A R F T V G F A I P L S I I A F T N H R I F R S I K Q S M G L S A A Q K A K V K H S A I A V V V I F L V C F A P Y H L V L L V K A A A F S Y Y R G D R N A M C G L E E R L Y T A S V V F L C L S T V N G V A D P I I Y V L A T D H S R Q E V S R I H K G W K E W S M K T D V T R L T H S R D T E E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8HQE	A	Orphan	Orphan	GPR132	Homo sapiens	-	-	Gi1/β1/γ2	2.97	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HQE (No Gprot)	A	Orphan	Orphan	GPR132	Homo sapiens	-	-		2.97	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HQM	A	Orphan	Orphan	GPR132	Homo sapiens	NPGLY	-	Gi1/β1/γ2	2.95	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HQM (No Gprot)	A	Orphan	Orphan	GPR132	Homo sapiens	NPGLY	-		2.95	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HQN	A	Orphan	Orphan	GPR132	Homo sapiens	9-S-HODE	-	Gi1/β1/γ2	3	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HQN (No Gprot)	A	Orphan	Orphan	GPR132	Homo sapiens	9-S-HODE	-		3	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HVI	A	Orphan	Orphan	GPR132	Homo sapiens	NOX-6-7	-	Gi1/β1/γ2	3.04	2023-10-11	doi.org/10.1038/s42255-023-00899-4
	8HVI (No Gprot)	A	Orphan	Orphan	GPR132	Homo sapiens	NOX-6-7	-		3.04	2023-10-11	doi.org/10.1038/s42255-023-00899-4

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