Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:W26 7.0025415
2R:R:N38 7.5925409
3R:R:Q48 7.148507
4R:R:L62 5.866529
5R:R:D66 8.0075429
6R:R:Y69 5.36518
7R:R:L73 7.5825418
8R:R:Q74 4.45333618
9R:R:W86 10.01718
10R:R:F92 8.3775414
11R:R:F96 6.69167616
12R:R:L100 6.6575418
13R:R:F101 8.854517
14R:R:S105 5.28407
15R:R:R118 5.938529
16R:R:Y119 6.416539
17R:R:L120 4.7575405
18R:R:F128 6.72508
19R:R:F132 6.6625407
20R:R:F152 7.698518
21R:R:Y159 5.6375405
22R:R:F170 9.6375406
23R:R:R172 6.255405
24R:R:R176 5.2675404
25R:R:F197 6.3425407
26R:R:Y198 8.2275409
27R:R:E313 4.735406
28R:R:Y332 10.346528
29R:R:I333 5.0375407
30R:R:H352 7.48444
31R:R:W360 6.95143718
32R:R:N366 8.018529
33R:R:Y370 5.952529
34R:R:F377 5.02333609
35L:L:?1 9.130831210
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:I158 R:R:P157 10.09955.08NoNo055
2R:R:I158 R:R:L155 23.77865.71NoNo058
3R:R:L155 R:R:Y159 25.09778.21NoYes085
4R:R:F152 R:R:Y159 28.89944.13YesYes085
5R:R:L100 R:R:L73 24.46266.92YesYes188
6R:R:F96 R:R:L73 24.840113.4YesYes168
7R:R:F96 R:R:W86 25.928210.02YesYes168
8R:R:T80 R:R:W86 14.35877.28NoYes068
9R:R:D79 R:R:T80 11.9871.45NoNo066
10L:L:?1 R:R:F152 36.33866.15YesYes108
11L:L:?1 R:R:L100 24.02748.98YesYes108
12L:L:?1 R:R:T167 19.5955.31YesNo004
13R:R:S77 R:R:T167 18.52026.4NoNo074
14R:R:F96 R:R:S77 17.44093.96YesNo067
15R:R:W360 R:R:Y81 21.2568.68YesNo085
16L:L:?1 R:R:W360 46.18945.75YesYes108
17R:R:M353 R:R:Y81 17.75185.99NoNo055
18R:R:M353 R:R:V16 11.66736.09NoNo056
19R:R:W26 R:R:W360 16.50834.69YesYes158
20R:R:L361 R:R:W26 10.40596.83NoYes055
21L:L:?1 R:R:N104 97.961418.81YesNo007
22R:R:N104 R:R:Y332 97.73944.65NoYes078
23R:R:N362 R:R:Y332 99.826816.28NoYes298
24R:R:N362 R:R:N366 10013.62NoYes299
25R:R:D66 R:R:N366 47.62848.08YesYes299
26R:R:D66 R:R:N38 45.11019.42YesYes099
27R:R:N38 R:R:T63 34.09587.31YesNo099
28R:R:T41 R:R:T63 30.61827.85NoNo099
29R:R:A371 R:R:T41 29.44135.03NoNo089
30R:R:A371 R:R:F377 28.25555.55NoYes089
31R:R:F377 R:R:L51 13.32832.44YesNo099
32R:R:L51 R:R:Q48 12.02714.64NoYes097
33R:R:F132 R:R:I137 13.10623.77YesNo077
34R:R:F128 R:R:F132 11.884912.86YesYes087
35R:R:F128 R:R:L120 18.23594.87YesYes085
36R:R:L116 R:R:L120 33.58064.15NoYes065
37R:R:F197 R:R:L116 34.76199.74YesNo076
38R:R:A115 R:R:F197 51.36794.16NoYes087
39R:R:A115 R:R:Y198 52.40725.34NoYes089
40R:R:R118 R:R:Y198 65.93988.23YesYes099
41R:R:R118 R:R:Y370 68.8717.2YesYes299
42R:R:N366 R:R:Y370 70.29674.65YesYes299
43R:R:F132 R:R:V131 11.7253.93YesNo075
44R:R:L120 R:R:V131 12.99524.47YesNo055
45R:R:S105 R:R:Y186 11.73837.63YesNo078
46R:R:F197 R:R:Y119 16.25516.19YesYes079
47R:R:I158 R:R:R174 12.90646.26NoNo055
48R:R:D171 R:R:R174 11.50747.15NoNo075
49L:L:?1 R:R:R172 23.02364.38YesYes005
50R:R:N339 R:R:R172 15.47796.03NoYes075
51R:R:L338 R:R:N339 27.89134.12NoNo057
52R:R:H352 R:R:L338 17.77859YesNo445
53L:L:?1 R:R:F335 17.485314.05YesNo008
54R:R:F335 R:R:N339 15.051510.87NoNo087
55R:R:F170 R:R:M183 10.18833.73YesNo068
56R:R:I333 R:R:L191 10.76124.28YesNo076
57R:R:F325 R:R:L191 12.0676.09NoNo086
58R:R:F325 R:R:V194 13.36385.24NoNo088
59R:R:F328 R:R:V194 15.93093.93NoNo098
60R:R:F328 R:R:Y332 19.71496.19NoYes098
61R:R:C321 R:R:Y198 16.15746.72NoYes089
62R:R:C321 R:R:V317 14.84281.71NoNo088
63R:R:V205 R:R:V317 10.84563.21NoNo088
64R:R:A347 R:R:H352 10.26382.93NoYes054
65R:R:G148 R:R:S105 13.86133.71NoYes087
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:N357 R:R:W26 7.91 1 No Yes 8 5 2 2
R:R:W26 R:R:W360 4.69 1 Yes Yes 5 8 2 1
R:R:L73 R:R:Y69 5.86 1 Yes Yes 8 8 2 2
R:R:Q74 R:R:Y69 4.51 1 Yes Yes 8 8 2 2
R:R:L100 R:R:Y69 5.86 1 Yes Yes 8 8 1 2
R:R:W360 R:R:Y69 6.75 1 Yes Yes 8 8 1 2
R:R:L100 R:R:L73 6.92 1 Yes Yes 8 8 1 2
R:R:Q74 R:R:W360 9.86 1 Yes Yes 8 8 2 1
R:R:S77 R:R:T167 6.4 0 No No 7 4 2 1
R:R:W360 R:R:Y81 8.68 1 Yes No 8 5 1 2
R:R:F101 R:R:L100 4.87 1 Yes Yes 7 8 1 1
L:L:?1 R:R:L100 8.98 1 Yes Yes 0 8 0 1
R:R:F101 R:R:F152 15 1 Yes Yes 7 8 1 1
R:R:F101 R:R:S169 7.93 1 Yes No 7 4 1 1
R:R:F101 R:R:F170 8.57 1 Yes Yes 7 6 1 2
L:L:?1 R:R:F101 7.9 1 Yes Yes 0 7 0 1
R:R:N104 R:R:Y332 4.65 0 No Yes 7 8 1 2
L:L:?1 R:R:N104 18.81 1 Yes No 0 7 0 1
R:R:F152 R:R:S105 5.28 1 Yes Yes 8 7 1 2
R:R:S105 R:R:Y186 7.63 0 Yes No 7 8 2 1
R:R:I108 R:R:Y186 4.84 0 No No 8 8 2 1
R:R:I108 R:R:Y332 15.71 0 No Yes 8 8 2 2
R:R:F152 R:R:S151 7.93 1 Yes No 8 7 1 2
R:R:F152 R:R:Y159 4.13 1 Yes Yes 8 5 1 2
L:L:?1 R:R:F152 6.15 1 Yes Yes 0 8 0 1
L:L:?1 R:R:V165 8.59 1 Yes No 0 4 0 1
L:L:?1 R:R:T167 5.31 1 Yes No 0 4 0 1
L:L:?1 R:R:S169 8.66 1 Yes No 0 4 0 1
R:R:F170 R:R:R172 10.69 0 Yes Yes 6 5 2 1
R:R:N339 R:R:R172 6.03 0 No Yes 7 5 2 1
L:L:?1 R:R:R172 4.38 1 Yes Yes 0 5 0 1
L:L:?1 R:R:Y186 9.3 1 Yes No 0 8 0 1
R:R:F335 R:R:N339 10.87 0 No No 8 7 1 2
R:R:A355 R:R:F335 4.16 0 No No 6 8 2 1
L:L:?1 R:R:F335 14.05 1 Yes No 0 8 0 1
R:R:N357 R:R:W360 9.04 1 No Yes 8 8 2 1
L:L:?1 R:R:T359 11.69 1 Yes No 0 8 0 1
L:L:?1 R:R:W360 5.75 1 Yes Yes 0 8 0 1
R:R:R172 R:R:V162 3.92 0 Yes No 5 3 1 2
R:R:A356 R:R:W360 3.89 0 No Yes 6 8 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 8J19_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.93
Number of Linked Nodes 270
Number of Links 291
Number of Hubs 35
Number of Links mediated by Hubs 139
Number of Communities 4
Number of Nodes involved in Communities 37
Number of Links involved in Communities 53
Path Summary
Number Of Nodes in MetaPath 66
Number Of Links MetaPath 65
Number of Shortest Paths 47427
Length Of Smallest Path 3
Average Path Length 12.9569
Length of Longest Path 28
Minimum Path Strength 1.41
Average Path Strength 7.31704
Maximum Path Strength 16.43
Minimum Path Correlation 0.7
Average Path Correlation 0.933816
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 5
Average % Of Corr. Nodes 56.5625
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 47.1746
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• fibroblast proliferation   • cell population proliferation   • cellular process   • cellular response to nitrogen compound   • cellular response to stimulus   • response to dopamine   • regulation of cellular process   • response to stimulus   • signaling   • cellular response to dopamine   • response to monoamine   • cell communication   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • signal transduction   • regulation of biological process   • G protein-coupled dopamine receptor signaling pathway   • biological regulation   • response to oxygen-containing compound   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to monoamine stimulus   • response to chemical   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to alcohol   • response to hormone   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex
Gene OntologyCellular Component• cellular anatomical structure   • membrane   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cell periphery   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • synapse   • cell junction   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • intracellular membrane-bounded organelle   • intracellular organelle   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • D2 dopamine receptor binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • enzyme regulator activity   • adenylate cyclase inhibitor activity   • cyclase regulator activity   • molecular function inhibitor activity   • cyclase inhibitor activity   • molecular function regulator activity   • enzyme inhibitor activity   • adenylate cyclase regulator activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • G-protein beta/gamma-subunit complex binding   • G protein activity   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • response to peptide hormone   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • cell migration   • T cell migration   • cell motility   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • positive regulation of biological process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • positive regulation of cellular process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • negative regulation of protein transport   • regulation of localization   • establishment of protein localization   • nitrogen compound transport   • negative regulation of biological process   • negative regulation of transport   • localization   • negative regulation of secretion   • negative regulation of hormone secretion   • negative regulation of secretion by cell   • intracellular protein localization   • regulation of biological quality   • regulation of peptide hormone secretion   • negative regulation of peptide hormone secretion   • regulation of hormone levels   • establishment of protein localization to extracellular region   • negative regulation of establishment of protein localization   • protein secretion   • establishment of localization   • regulation of protein secretion   • regulation of secretion   • negative regulation of protein secretion   • regulation of hormone secretion   • regulation of protein localization   • regulation of peptide secretion   • transport   • negative regulation of signaling   • hormone secretion   • negative regulation of cell communication   • protein localization to extracellular region   • negative regulation of peptide secretion   • peptide secretion   • regulation of secretion by cell   • secretion by cell   • amide transport   • signal release   • negative regulation of cellular process   • negative regulation of protein localization   • regulation of signaling   • regulation of transport   • secretion   • regulation of peptide transport   • regulation of establishment of protein localization   • export from cell   • regulation of protein transport   • peptide transport   • negative regulation of insulin secretion   • protein transport   • regulation of insulin secretion   • peptide hormone secretion   • macromolecule localization   • hormone transport   • regulation of cell communication   • insulin secretion   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • positive regulation of protein localization to cell periphery   • protein localization to cell periphery   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • regulation of protein localization to cell cortex   • positive regulation of protein localization   • protein localization to cell cortex   • cellular response to forskolin   • response to forskolin   • midbody   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • nucleolus   • intracellular organelle lumen   • organelle lumen   • membraneless organelle   • nuclear lumen   • cell cortex   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • nucleoplasm   • Golgi apparatus   • endomembrane system   • ciliary basal body   • urotensin II receptor activity   • peptide receptor activity   • molecular transducer activity   • G protein-coupled receptor activity   • G protein-coupled peptide receptor activity   • signaling receptor activity   • transmembrane signaling receptor activity   • neuropeptide signaling pathway   • receptor complex   • tertiary granule membrane   • intracellular vesicle   • tertiary granule   • cytoplasmic vesicle membrane   • vesicle membrane   • cytoplasmic vesicle   • secretory granule   • secretory vesicle   • secretory granule membrane   • specific granule membrane   • specific granule
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain   • Ras-like P-loop GTPases
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeSWO
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
CodeSWO
Name6-nonylpyridine-2,4-diol
Synonyms
Identifier
FormulaC14 H23 N O2
Molecular Weight237.338
SMILES
PubChem127045422
Formal Charge0
Total Atoms40
Total Chiral Atoms0
Total Bonds40
Total Aromatic Bonds6

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtQ9NQS5
Sequence
>8J19_nogp_Chain_R
NFSCYHESV LGYRYVAVS WGVVVAVTG TVGNVLTLL ALAIQPKLR 
TRFNLLIAN LTLADLLYC TLLQPFSVD TYLHLHWRT GATFCRVFG 
LLLFASNSV SILTLCLIA LGRYLLIAH PKLFPQVFS AKGIVLALV 
STWVVGVAS FAPLWPIYI LVPVVCTCS FDRIRGRPY TTILMGIYF 
VLGLSSVGI FYCLIHRQV KRAAQALDQ YKLEFGKVT RMCFAVFLC 
FALSYIPFL LLNILDARV QAPRVVHML AANLTWLNG CINPVLYAA 
MNRQFRQAY GSIL


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

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This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8J18AOrphanOrphanGPR84Homo sapiens(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ22.892023-06-21doi.org/10.1038/s41467-023-38985-6
8J18 (No Gprot) AOrphanOrphanGPR84Homo sapiens(3R)-3-Hydroxydodecanoic acid-2.892023-06-21doi.org/10.1038/s41467-023-38985-6
8J19AOrphanOrphanGPR84Homo sapiensLY237-Gi1/β1/γ23.232023-06-21doi.org/10.1038/s41467-023-38985-6
8J19 (No Gprot) AOrphanOrphanGPR84Homo sapiensLY237-3.232023-06-21doi.org/10.1038/s41467-023-38985-6
8J1AAOrphanOrphanGPR84Homo sapiens--Gi1/β1/γ23.242023-06-21doi.org/10.1038/s41467-023-38985-6
8J1A (No Gprot) AOrphanOrphanGPR84Homo sapiens--3.242023-06-21doi.org/10.1038/s41467-023-38985-6
8G05AOrphanOrphanGPR84Homo sapiens6-OAU-Gi1/β1/γ232023-11-01doi.org/10.1038/s41467-023-41201-0
8G05 (No Gprot) AOrphanOrphanGPR84Homo sapiens6-OAU-32023-11-01doi.org/10.1038/s41467-023-41201-0




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Download 8J19_nogp.zip



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