psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D9	R:R:K263	6.91	No	No	0	6	3
2	R:R:C10	R:R:F12	4.19	No	No	0	8	5
3	R:R:D13	R:R:L11	6.79	No	No	0	3	4
4	R:R:F12	R:R:S267	6.61	No	No	0	5	4
5	R:R:D13	R:R:G14	5.03	No	No	0	3	3
6	R:R:E17	R:R:G14	4.91	No	No	0	3	3
7	R:R:F268	R:R:V15	3.93	No	No	0	2	5
8	R:R:H170	R:R:N16	5.1	No	No	0	5	5
9	R:R:L18	R:R:L22	4.15	No	No	0	4	5
10	R:R:F268	R:R:L18	6.09	No	No	0	2	4
11	R:R:L22	R:R:M19	4.24	No	Yes	3	5	5
12	R:R:F268	R:R:M19	6.22	No	Yes	0	2	5
13	R:R:M19	R:R:Q271	13.59	Yes	No	0	5	5
14	R:R:L272	R:R:M19	4.24	No	Yes	3	5	5
15	R:R:K20	R:R:Q85	14.92	No	No	0	5	4
16	R:R:L22	R:R:L272	4.15	No	No	3	5	5
17	R:R:F24	R:R:Q23	5.86	No	Yes	1	5	5
18	R:R:H27	R:R:Q23	4.95	Yes	Yes	1	7	5
19	R:R:M81	R:R:Q23	4.08	Yes	Yes	1	7	5
20	R:R:Q23	R:R:S84	4.33	Yes	No	0	5	6
21	R:R:F24	R:R:M81	6.22	No	Yes	1	5	7
22	R:R:F24	R:R:Q85	4.68	No	No	0	5	4
23	R:R:F276	R:R:V26	5.24	No	No	0	6	5
24	R:R:H27	R:R:L77	10.29	Yes	No	0	7	8
25	R:R:H27	R:R:K80	11.79	Yes	No	1	7	7
26	R:R:H27	R:R:M81	6.57	Yes	Yes	1	7	7
27	R:R:C275	R:R:H27	7.37	No	Yes	0	5	7
28	R:R:H27	R:R:N278	6.38	Yes	No	1	7	6
29	R:R:I28	R:R:M81	5.83	No	Yes	0	4	7
30	R:R:F31	R:R:P78	11.56	No	No	0	7	9
31	R:R:L37	R:R:V285	7.45	Yes	No	0	7	9
32	R:R:F286	R:R:L37	4.87	No	Yes	0	5	7
33	R:R:D70	R:R:N38	8.08	Yes	No	0	9	9
34	R:R:N38	R:R:V285	4.43	No	No	0	9	9
35	R:R:L39	R:R:L71	4.15	No	No	0	3	7
36	R:R:I299	R:R:L40	9.99	No	No	0	6	5
37	R:R:A41	R:R:Y289	4	No	Yes	0	9	7
38	R:R:H43	R:R:T47	4.11	No	No	0	4	3
39	R:R:F45	R:R:S60	3.96	Yes	No	0	7	7
40	R:R:F45	R:R:M63	13.68	Yes	Yes	2	7	8
41	R:R:F45	R:R:Y289	9.28	Yes	Yes	2	7	7
42	R:R:F295	R:R:F45	5.36	Yes	Yes	2	8	7
43	R:R:F48	R:R:R52	8.55	No	No	0	6	6
44	R:R:F48	R:R:S60	3.96	No	No	0	6	7
45	R:R:F48	R:R:N298	7.25	No	No	0	6	5
46	R:R:D55	R:R:R52	10.72	No	No	4	6	6
47	R:R:R52	R:R:Y56	6.17	No	No	4	6	4
48	R:R:P54	R:R:W53	4.05	No	No	0	6	5
49	R:R:A57	R:R:W53	12.96	No	No	0	7	5
50	R:R:P135	R:R:W53	9.46	No	No	0	4	5
51	R:R:D55	R:R:P54	4.83	No	No	0	6	6
52	R:R:D55	R:R:Y56	11.49	No	No	4	6	4
53	R:R:E294	R:R:Y56	11.22	No	No	0	7	4
54	R:R:A58	R:R:R133	5.53	No	Yes	0	7	7
55	R:R:A58	R:R:I138	4.87	No	No	0	7	8
56	R:R:T59	R:R:Y62	11.24	No	Yes	0	7	8
57	R:R:R133	R:R:T59	5.17	Yes	No	0	7	7
58	R:R:M63	R:R:Y62	8.38	Yes	Yes	2	8	8
59	R:R:F114	R:R:Y62	9.28	Yes	Yes	0	5	8
60	R:R:I115	R:R:Y62	15.71	No	Yes	2	8	8
61	R:R:D118	R:R:Y62	6.9	No	Yes	0	8	8
62	R:R:I115	R:R:M63	4.37	No	Yes	2	8	8
63	R:R:M63	R:R:Y289	4.79	Yes	Yes	2	8	7
64	R:R:F69	R:R:N65	6.04	No	Yes	5	8	9
65	R:R:N65	R:R:T111	7.31	Yes	No	0	9	8
66	R:R:C142	R:R:N65	12.6	No	Yes	0	6	9
67	R:R:N65	R:R:W146	11.3	Yes	Yes	5	9	9
68	R:R:L66	R:R:T111	7.37	Yes	No	0	9	8
69	R:R:I112	R:R:L66	4.28	No	Yes	2	8	9
70	R:R:D284	R:R:L66	9.5	Yes	Yes	2	9	9
71	R:R:L66	R:R:Y289	7.03	Yes	Yes	2	9	7
72	R:R:A67	R:R:Y289	4	No	Yes	0	8	7
73	R:R:F69	R:R:G107	9.03	No	No	0	8	7
74	R:R:F69	R:R:W146	27.06	No	Yes	5	8	9
75	R:R:C281	R:R:D70	4.67	No	Yes	0	8	9
76	R:R:D284	R:R:D70	9.31	Yes	Yes	0	9	9
77	R:R:L100	R:R:L72	4.15	No	No	0	4	7
78	R:R:L72	R:R:S104	6.01	No	No	0	7	9
79	R:R:L73	R:R:Y101	4.69	No	Yes	1	6	5
80	R:R:L73	R:R:S104	4.5	No	No	0	6	9
81	R:R:L73	R:R:N278	6.87	No	No	1	6	6
82	R:R:L100	R:R:S76	4.5	No	No	0	4	7
83	R:R:S76	R:R:Y101	5.09	No	Yes	0	7	5
84	R:R:F79	R:R:V97	3.93	No	No	0	6	5
85	R:R:K80	R:R:Y101	13.14	No	Yes	1	7	5
86	R:R:F169	R:R:K80	16.13	Yes	No	1	4	7
87	R:R:L83	R:R:L93	5.54	No	No	0	5	5
88	R:R:C168	R:R:L83	4.76	No	No	0	9	5
89	R:R:Q85	R:R:S84	5.78	No	No	0	4	6
90	R:R:M167	R:R:Q87	4.08	No	No	0	3	3
91	R:R:C94	R:R:K165	4.85	No	Yes	0	9	2
92	R:R:C168	R:R:C94	7.28	No	No	0	9	9
93	R:R:E98	R:R:Y157	5.61	Yes	Yes	1	6	4
94	R:R:E98	R:R:K165	6.75	Yes	Yes	0	6	2
95	R:R:E98	R:R:F169	13.99	Yes	Yes	1	6	4
96	R:R:E98	R:R:M172	5.41	Yes	Yes	1	6	4
97	L:L:?1	R:R:E98	4.68	Yes	Yes	1	0	6
98	R:R:C99	R:R:Y157	9.41	No	Yes	0	5	4
99	R:R:F102	R:R:Y101	13.41	Yes	Yes	1	5	5
100	R:R:M105	R:R:Y101	5.99	No	Yes	0	8	5
101	R:R:F169	R:R:Y101	7.22	Yes	Yes	1	4	5
102	R:R:N278	R:R:Y101	12.79	No	Yes	1	6	5
103	R:R:F102	R:R:Y157	4.13	Yes	Yes	1	5	4
104	R:R:F102	R:R:F169	5.36	Yes	Yes	1	5	4
105	L:L:?1	R:R:F102	26.65	Yes	Yes	1	0	5
106	R:R:V103	R:R:W150	15.94	No	No	0	5	3
107	R:R:H243	R:R:Y106	5.44	Yes	No	0	8	8
108	L:L:?1	R:R:Y106	14.89	Yes	No	0	0	8
109	R:R:F235	R:R:V109	3.93	Yes	No	2	9	8
110	R:R:F239	R:R:V109	7.87	Yes	No	2	9	8
111	R:R:D284	R:R:I112	8.4	Yes	No	2	9	8
112	R:R:I112	R:R:Y288	7.25	No	Yes	2	8	9
113	R:R:F114	R:R:I138	5.02	Yes	No	0	5	8
114	R:R:F114	R:R:I141	13.82	Yes	No	0	5	5
115	R:R:I115	R:R:R119	7.52	No	No	0	8	9
116	R:R:M197	R:R:S116	4.6	No	No	0	7	9
117	R:R:C200	R:R:S116	5.16	No	No	0	7	9
118	R:R:L121	R:R:M117	8.48	No	No	0	5	5
119	R:R:D118	R:R:R133	14.29	No	Yes	0	8	7
120	R:R:R119	R:R:Y288	6.17	No	Yes	0	9	9
121	R:R:F120	R:R:R124	5.34	Yes	No	0	8	6
122	R:R:F120	R:R:F199	4.29	Yes	No	6	8	4
123	R:R:C200	R:R:F120	6.98	No	Yes	0	7	8
124	R:R:F120	R:R:R203	4.28	Yes	Yes	6	8	4
125	R:R:F120	R:R:S204	3.96	Yes	No	0	8	7
126	R:R:A122	R:R:V129	5.09	No	No	0	8	6
127	R:R:I123	R:R:I207	4.42	No	No	0	8	6
128	R:R:I123	R:R:L208	5.71	No	No	0	8	8
129	R:R:R124	R:R:Y125	21.61	No	No	0	6	6
130	R:R:L128	R:R:Y125	4.69	No	No	0	5	6
131	R:R:R133	R:R:V129	3.92	Yes	No	0	7	6
132	R:R:H131	R:R:S130	4.18	No	No	0	4	4
133	R:R:K137	R:R:S134	9.18	No	No	0	3	6
134	R:R:F139	R:R:R136	9.62	No	No	0	4	4
135	R:R:C143	R:R:F139	4.19	No	No	0	4	4
136	R:R:G152	R:R:P155	4.06	No	No	0	4	7
137	R:R:I156	R:R:L185	4.28	No	No	0	4	5
138	R:R:H160	R:R:Y157	11.98	Yes	Yes	0	5	4
139	L:L:?1	R:R:Y157	9.93	Yes	Yes	1	0	4
140	R:R:F159	R:R:S158	5.28	No	No	0	4	3
141	R:R:D175	R:R:F159	5.97	No	No	0	2	4
142	R:R:H160	R:R:K165	5.24	Yes	Yes	0	5	2
143	R:R:H160	R:R:M172	5.25	Yes	Yes	0	5	4
144	R:R:H160	R:R:T176	8.21	Yes	No	0	5	2
145	R:R:D175	R:R:K162	5.53	No	No	0	2	4
146	R:R:K165	R:R:V163	15.18	Yes	No	0	2	1
147	R:R:E164	R:R:Y166	13.47	No	No	0	1	5
148	H:H:?2	R:R:Y166	21.04	No	No	0	0	5
149	R:R:C168	R:R:F169	4.19	No	Yes	0	9	4
150	L:L:?1	R:R:F169	10.32	Yes	Yes	1	0	4
151	H:H:?1	R:R:N171	25.87	Yes	No	0	0	4
152	R:R:M172	R:R:W177	4.65	Yes	Yes	1	4	3
153	L:L:?1	R:R:M172	14.97	Yes	Yes	1	0	4
154	R:R:D175	R:R:S173	7.36	No	No	0	2	4
155	R:R:D174	R:R:R253	9.53	No	No	0	2	4
156	L:L:?1	R:R:T176	8.32	Yes	No	0	0	2
157	R:R:F182	R:R:W177	4.01	Yes	Yes	1	5	3
158	R:R:Q249	R:R:W177	5.48	Yes	Yes	1	5	3
159	R:R:R253	R:R:W177	14.99	No	Yes	0	4	3
160	L:L:?1	R:R:W177	21.71	Yes	Yes	1	0	3
161	R:R:K180	R:R:S178	4.59	No	No	0	3	4
162	R:R:K180	R:R:V181	6.07	No	No	0	3	5
163	R:R:F182	R:R:F183	9.65	Yes	Yes	1	5	4
164	R:R:E186	R:R:F182	8.16	No	Yes	0	5	5
165	R:R:F182	R:R:F250	24.65	Yes	No	1	5	5
166	L:L:?1	R:R:F182	4.3	Yes	Yes	1	0	5
167	R:R:F183	R:R:F250	8.57	Yes	No	1	4	5
168	L:L:?1	R:R:L185	4.88	Yes	No	0	0	5
169	R:R:E186	R:R:H243	11.08	No	Yes	0	5	8
170	R:R:G189	R:R:P193	4.06	No	Yes	0	6	9
171	R:R:F190	R:R:M194	6.22	Yes	No	0	9	5
172	R:R:F190	R:R:L240	6.09	Yes	No	0	9	5
173	R:R:F190	R:R:H243	24.89	Yes	Yes	0	9	8
174	R:R:L192	R:R:P193	4.93	No	Yes	0	5	9
175	R:R:I196	R:R:L192	4.28	No	No	0	6	5
176	R:R:F235	R:R:M194	6.22	Yes	No	0	9	5
177	R:R:M194	R:R:V236	6.09	No	No	0	5	5
178	R:R:F235	R:R:M197	11.2	Yes	No	0	9	7
179	R:R:F199	R:R:R203	11.76	No	Yes	6	4	4
180	R:R:C201	R:R:L232	7.94	No	No	0	8	8
181	R:R:I207	R:R:R203	7.52	No	Yes	0	6	4
182	R:R:I205	R:R:I225	5.89	Yes	No	7	4	5
183	R:R:I205	R:R:I228	5.89	Yes	No	0	4	7
184	R:R:I225	R:R:L208	4.28	No	No	0	5	8
185	R:R:Q221	R:R:R211	7.01	No	No	0	6	5
186	R:R:R212	R:R:W218	13.99	No	Yes	0	3	4
187	R:R:D217	R:R:T215	5.78	No	No	0	5	3
188	R:R:V219	R:R:W218	7.36	No	Yes	0	4	4
189	R:R:Q220	R:R:Q221	6.4	No	No	0	5	6
190	R:R:K222	R:R:Y226	11.94	No	No	0	5	5
191	R:R:S227	R:R:V291	4.85	No	No	0	7	6
192	R:R:S231	R:R:Y288	10.17	No	Yes	0	7	9
193	R:R:C287	R:R:V234	5.12	No	No	0	7	7
194	R:R:F235	R:R:F239	8.57	Yes	Yes	2	9	9
195	R:R:F239	R:R:S238	3.96	Yes	No	2	9	7
196	R:R:N280	R:R:S238	8.94	No	No	2	9	7
197	R:R:F239	R:R:N280	8.46	Yes	No	2	9	9
198	R:R:H243	R:R:V242	4.15	Yes	Yes	1	8	7
199	R:R:F246	R:R:V242	3.93	Yes	Yes	1	6	7
200	R:R:S273	R:R:V242	4.85	No	Yes	0	7	7
201	R:R:S277	R:R:V242	9.7	No	Yes	0	8	7
202	R:R:F246	R:R:H243	5.66	Yes	Yes	1	6	8
203	R:R:F269	R:R:L244	6.09	No	No	0	5	5
204	R:R:F246	R:R:L270	4.87	Yes	No	0	6	5
205	R:R:F246	R:R:M274	6.22	Yes	No	1	6	6
206	L:L:?1	R:R:F246	12.04	Yes	Yes	1	0	6
207	R:R:F247	R:R:L251	10.96	No	No	0	5	4
208	R:R:I266	R:R:L248	8.56	Yes	No	0	5	4
209	R:R:Q249	R:R:V252	4.3	Yes	No	1	5	3
210	R:R:I266	R:R:Q249	4.12	Yes	Yes	1	5	5
211	R:R:Q249	R:R:S267	5.78	Yes	No	0	5	4
212	R:R:L270	R:R:Q249	3.99	No	Yes	0	5	5
213	R:R:F250	R:R:N254	13.29	No	No	0	5	3
214	R:R:F256	R:R:L251	7.31	No	No	0	2	4
215	R:R:I257	R:R:L251	4.28	No	No	0	2	4
216	R:R:K263	R:R:V252	6.07	No	No	0	3	3
217	R:R:I266	R:R:V252	6.14	Yes	No	1	5	3
218	R:R:I257	R:R:I266	5.89	No	Yes	0	2	5
219	R:R:E259	R:R:R261	5.82	No	No	0	5	3
220	R:R:F276	R:R:L272	6.09	No	No	0	6	5
221	L:L:?1	R:R:M274	6.99	Yes	No	1	0	6
222	R:R:D284	R:R:N280	13.46	Yes	No	2	9	9
223	R:R:D284	R:R:Y288	5.75	Yes	Yes	2	9	9
224	R:R:V285	R:R:Y289	10.09	No	Yes	0	9	7
225	R:R:F286	R:R:F290	6.43	No	No	0	5	8
226	R:R:F295	R:R:Y289	6.19	Yes	Yes	2	8	7
227	R:R:F290	R:R:F295	6.43	No	Yes	0	8	8
228	R:R:E294	R:R:I292	5.47	No	No	0	7	7
229	R:R:K293	R:R:M297	5.76	No	No	0	6	5
230	H:H:?1	H:H:?2	39.01	Yes	No	0	0	0
231	R:R:F45	R:R:I64	3.77	Yes	No	0	7	5
232	R:R:F139	R:R:I61	3.77	No	No	0	4	6
233	R:R:F114	R:R:I145	3.77	Yes	No	0	5	6
234	R:R:T95	R:R:Y157	3.75	No	Yes	0	7	4
235	R:R:W146	R:R:W150	3.75	Yes	No	0	9	3
236	R:R:K293	R:R:R296	3.71	No	No	0	6	8
237	R:R:V68	R:R:W146	3.68	No	Yes	0	5	9
238	R:R:F31	R:R:L77	3.65	No	No	0	7	8
239	R:R:F120	R:R:L121	3.65	Yes	No	0	8	5
240	R:R:F190	R:R:L191	3.65	Yes	No	0	9	4
241	R:R:P89	R:R:S88	3.56	No	No	0	4	8
242	R:R:P135	R:R:S134	3.56	No	No	0	4	6
243	R:R:P193	R:R:V109	3.53	Yes	No	0	9	8
244	R:R:F12	R:R:Q264	3.51	No	Yes	0	5	4
245	H:H:?1	R:R:H170	3.46	Yes	No	0	0	5
246	R:R:C94	R:R:S88	3.44	No	No	0	9	8
247	R:R:C99	R:R:S153	3.44	No	No	0	5	6
248	R:R:C287	R:R:S231	3.44	No	No	0	7	7
249	R:R:C281	R:R:V74	3.42	No	No	0	8	5
250	R:R:G198	R:R:L232	3.42	No	No	0	4	8
251	R:R:G245	R:R:L248	3.42	No	No	0	5	4
252	R:R:I28	R:R:P29	3.39	No	No	0	4	4
253	R:R:I154	R:R:P155	3.39	No	No	0	4	7
254	R:R:L240	R:R:P241	3.28	No	No	0	5	9
255	R:R:C201	R:R:I228	3.27	No	No	0	8	7
256	R:R:A67	R:R:I42	3.25	No	No	0	8	7
257	R:R:S173	R:R:V163	3.23	No	No	0	4	1
258	R:R:V103	R:R:V149	3.21	No	No	0	5	7
259	R:R:T30	R:R:V279	3.17	No	No	0	7	4
260	R:R:C282	R:R:L37	3.17	No	Yes	0	7	7
261	R:R:T151	R:R:V147	3.17	No	No	0	3	4
262	R:R:I154	R:R:S153	3.1	No	No	0	4	6
263	R:R:C224	R:R:Q221	3.05	No	No	0	7	6
264	R:R:F295	R:R:G44	3.01	Yes	No	0	8	7
265	R:R:F110	R:R:G189	3.01	No	No	0	5	6
266	R:R:F269	R:R:G245	3.01	No	No	0	5	5
267	R:R:L49	R:R:S60	3	No	No	0	5	7
268	R:R:L283	R:R:S238	3	No	No	0	7	7
269	R:R:L35	R:R:V74	2.98	No	No	0	5	5
270	R:R:L93	R:R:V97	2.98	No	No	0	5	5
271	R:R:L185	R:R:V181	2.98	No	No	0	5	5
272	R:R:L283	R:R:V279	2.98	No	No	0	7	4
273	R:R:L148	R:R:T144	2.95	No	No	0	4	3
274	R:R:I138	R:R:I61	2.94	No	No	0	8	6
275	R:R:D70	R:R:S108	2.94	Yes	No	0	9	9
276	R:R:Q264	R:R:V15	2.87	Yes	No	0	4	5
277	R:R:I205	R:R:L209	2.85	Yes	No	7	4	3
278	R:R:I225	R:R:L209	2.85	No	No	7	5	3
279	R:R:L33	R:R:L37	2.77	No	Yes	0	5	7
280	R:R:A179	R:R:F183	2.77	No	Yes	0	3	4
281	R:R:L71	R:R:N38	2.75	No	No	0	7	9
282	R:R:N16	R:R:Q271	2.64	No	No	0	5	5
283	H:H:?1	R:R:M167	2.54	Yes	No	0	0	3
284	R:R:D213	R:R:H214	2.52	No	No	0	3	4
285	R:R:F295	R:R:I299	2.51	Yes	No	0	8	6
286	R:R:F188	R:R:L192	2.44	No	No	0	4	5
287	R:R:D213	R:R:R212	2.38	No	No	0	3	3
288	R:R:L209	R:R:W218	2.28	No	Yes	0	3	4
289	R:R:H206	R:R:R203	2.26	No	Yes	0	4	4
290	R:R:R211	R:R:W218	2	No	Yes	0	5	4
291	R:R:C281	R:R:G34	1.96	No	No	0	8	9
292	R:R:C282	R:R:G34	1.96	No	No	0	7	9
293	R:R:C143	R:R:G140	1.96	No	No	0	4	1
294	R:R:C113	R:R:P193	1.88	No	Yes	0	7	9
295	R:R:G44	R:R:T47	1.82	No	No	0	7	3
296	R:R:A230	R:R:C287	1.81	No	No	0	5	7
297	R:R:A262	R:R:S265	1.71	No	No	0	1	3
298	R:R:A229	R:R:I205	1.62	No	Yes	0	3	4
299	R:R:A262	R:R:I257	1.62	No	No	0	1	2
300	R:R:V82	R:R:V86	1.6	No	No	0	4	4
301	R:R:I42	R:R:S46	1.55	No	No	0	7	3
302	R:R:I64	R:R:S46	1.55	No	No	0	5	3
303	R:R:I292	R:R:V291	1.54	No	No	0	7	6
304	R:R:C260	R:R:Q264	1.53	No	Yes	0	7	4
305	R:R:A262	R:R:E259	1.51	No	No	0	1	5
306	R:R:K20	R:R:T21	1.5	No	No	0	5	3
307	R:R:G210	R:R:R212	1.5	No	No	0	5	3
308	R:R:L33	R:R:V32	1.49	No	No	0	5	5
309	R:R:L36	R:R:V32	1.49	No	No	0	4	5
310	R:R:L83	R:R:V82	1.49	No	No	0	5	4
311	R:R:L191	R:R:V187	1.49	No	No	0	4	4
312	R:R:D9	R:R:V258	1.46	No	No	0	6	2
313	R:R:F90	R:R:P89	1.44	No	No	0	6	4
314	R:R:F90	R:R:P91	1.44	No	No	0	6	6
315	R:R:F183	R:R:P184	1.44	Yes	No	0	4	4
316	R:R:K50	R:R:N51	1.4	No	No	0	5	5
317	R:R:P126	R:R:Y125	1.39	No	No	0	8	6
318	R:R:L35	R:R:L75	1.38	No	No	0	5	4
319	R:R:L71	R:R:L75	1.38	No	No	0	7	4
320	R:R:L93	R:R:L96	1.38	No	No	0	5	4
321	R:R:L127	R:R:L128	1.38	No	No	0	5	5
322	R:R:E294	R:R:K293	1.35	No	No	0	7	6
323	R:R:L11	R:R:Q264	1.33	No	Yes	0	4	4
324	R:R:R203	R:R:S202	1.32	Yes	No	0	4	3
325	R:R:H131	R:R:L132	1.29	No	No	0	4	4
326	R:R:R211	R:R:T215	1.29	No	No	0	5	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:M19	7.0725	4	3	5
2	R:R:Q23	4.805	4	1	5
3	R:R:H27	7.89167	6	1	7
4	R:R:L37	4.565	4	0	7
5	R:R:F45	7.21	5	2	7
6	R:R:Y62	10.302	5	2	8
7	R:R:M63	7.805	4	2	8
8	R:R:N65	9.3125	4	5	9
9	R:R:L66	7.045	4	2	9
10	R:R:D70	6.25	4	0	9
11	R:R:M81	5.675	4	1	7
12	R:R:E98	7.288	5	1	6
13	R:R:Y101	8.90429	7	1	5
14	R:R:F102	12.3875	4	1	5
15	R:R:F114	7.9725	4	0	5
16	R:R:F120	4.75	6	6	8
17	R:R:R133	7.2275	4	0	7
18	R:R:W146	11.4475	4	5	9
19	R:R:Y157	7.46833	6	1	4
20	R:R:H160	7.67	4	0	5
21	R:R:K165	8.005	4	0	2
22	R:R:F169	9.535	6	1	4
23	R:R:M172	7.57	4	1	4
24	R:R:W177	10.168	5	1	3
25	R:R:F182	10.154	5	1	5
26	R:R:F183	5.6075	4	1	4
27	R:R:F190	10.2125	4	0	9
28	R:R:P193	3.6	4	0	9
29	R:R:R203	5.428	5	6	4
30	R:R:I205	4.0625	4	7	4
31	R:R:W218	6.4075	4	0	4
32	R:R:F235	7.48	4	2	9
33	R:R:F239	7.215	4	2	9
34	R:R:V242	5.6575	4	1	7
35	R:R:H243	10.244	5	1	8
36	R:R:F246	6.544	5	1	6
37	R:R:Q249	4.734	5	1	5
38	R:R:Q264	2.31	4	0	4
39	R:R:I266	6.1775	4	1	5
40	R:R:D284	9.284	5	2	9
41	R:R:Y288	7.335	4	2	9
42	R:R:Y289	6.48286	7	2	7
43	R:R:F295	4.7	5	2	8
44	H:H:?1	17.72	4	0	0
45	L:L:?1	11.64	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F12	R:R:S267	20.1492	6.61	No	No	0	5	4
2	R:R:Q249	R:R:S267	20.779	5.78	Yes	No	0	5	4
3	R:R:F12	R:R:Q264	18.7621	3.51	No	Yes	0	5	4
4	R:R:Q264	R:R:V15	14.4917	2.87	Yes	No	0	4	5
5	R:R:F268	R:R:V15	13.764	3.93	No	No	0	2	5
6	R:R:F268	R:R:M19	11.506	6.22	No	Yes	0	2	5
7	R:R:Q249	R:R:W177	12.5338	5.48	Yes	Yes	1	5	3
8	L:L:?1	R:R:W177	11.6379	21.71	Yes	Yes	1	0	3
9	L:L:?1	R:R:F169	45.3169	10.32	Yes	Yes	1	0	4
10	R:R:F169	R:R:K80	24.4628	16.13	Yes	No	1	4	7
11	R:R:H27	R:R:K80	24.008	11.79	Yes	No	1	7	7
12	R:R:H27	R:R:Q23	10.7738	4.95	Yes	Yes	1	7	5
13	R:R:F102	R:R:Y101	10.0371	13.41	Yes	Yes	1	5	5
14	R:R:L270	R:R:Q249	19.8126	3.99	No	Yes	0	5	5
15	R:R:F246	R:R:L270	20.3379	4.87	Yes	No	0	6	5
16	R:R:F246	R:R:H243	57.3732	5.66	Yes	Yes	1	6	8
17	R:R:F190	R:R:H243	100	24.89	Yes	Yes	0	9	8
18	R:R:F190	R:R:M194	99.2723	6.22	Yes	No	0	9	5
19	R:R:F235	R:R:M194	98.9494	6.22	Yes	No	0	9	5
20	R:R:F235	R:R:F239	83.5209	8.57	Yes	Yes	2	9	9
21	R:R:F239	R:R:N280	82.7523	8.46	Yes	No	2	9	9
22	R:R:D284	R:R:N280	83.4618	13.46	Yes	No	2	9	9
23	R:R:D284	R:R:L66	52.8367	9.5	Yes	Yes	2	9	9
24	R:R:L66	R:R:Y289	47.1974	7.03	Yes	Yes	2	9	7
25	R:R:D284	R:R:D70	12.9613	9.31	Yes	Yes	0	9	9
26	R:R:F45	R:R:Y289	18.1481	9.28	Yes	Yes	2	7	7
27	R:R:F45	R:R:S60	17.6592	3.96	Yes	No	0	7	7
28	R:R:M63	R:R:Y289	17.375	4.79	Yes	Yes	2	8	7
29	R:R:F48	R:R:S60	15.9629	3.96	No	No	0	6	7
30	R:R:F48	R:R:R52	14.262	8.55	No	No	0	6	6
31	R:R:M63	R:R:Y62	17.9548	8.38	Yes	Yes	2	8	8
32	R:R:F114	R:R:I138	11.199	5.02	Yes	No	0	5	8
33	R:R:F114	R:R:Y62	15.9515	9.28	Yes	Yes	0	5	8
34	R:R:I115	R:R:Y62	14.9487	15.71	No	Yes	2	8	8
35	R:R:I115	R:R:R119	15.9834	7.52	No	No	0	8	9
36	R:R:R119	R:R:Y288	16.5496	6.17	No	Yes	0	9	9
37	R:R:D284	R:R:Y288	20.2083	5.75	Yes	Yes	2	9	9
38	R:R:C168	R:R:F169	14.3461	4.19	No	Yes	0	9	4
39	R:R:E98	R:R:K165	14.0164	6.75	Yes	Yes	0	6	2
40	L:L:?1	R:R:E98	12.784	4.68	Yes	Yes	1	0	6
41	L:L:?1	R:R:Y106	37.2172	14.89	Yes	No	0	0	8
42	R:R:F235	R:R:M197	34.0815	11.2	Yes	No	0	9	7
43	R:R:M197	R:R:S116	33.2901	4.6	No	No	0	7	9
44	R:R:C200	R:R:S116	32.4943	5.16	No	No	0	7	9
45	R:R:C200	R:R:F120	31.6938	6.98	No	Yes	0	7	8
46	R:R:F120	R:R:R203	23.3804	4.28	Yes	Yes	6	8	4
47	R:R:I207	R:R:R203	20.8745	7.52	No	Yes	0	6	4
48	R:R:I123	R:R:I207	20.0082	4.42	No	No	0	8	6
49	R:R:I123	R:R:L208	19.1327	5.71	No	No	0	8	8
50	R:R:I225	R:R:L208	18.2573	4.28	No	No	0	5	8
51	R:R:I225	R:R:L209	11.9244	2.85	No	No	7	5	3
52	R:R:L209	R:R:W218	11.1877	2.28	No	Yes	0	3	4
53	R:R:I266	R:R:Q249	10.0098	4.12	Yes	Yes	1	5	5
54	R:R:H243	R:R:Y106	37.3673	5.44	Yes	No	0	8	8
55	L:L:?1	R:R:F246	37.9858	12.04	Yes	Yes	1	0	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:K80	R:R:Y101	13.14	1	No	Yes	7	5	2	2
R:R:F169	R:R:K80	16.13	1	Yes	No	4	7	1	2
R:R:E98	R:R:Y157	5.61	1	Yes	Yes	6	4	1	1
R:R:E98	R:R:K165	6.75	1	Yes	Yes	6	2	1	2
R:R:E98	R:R:F169	13.99	1	Yes	Yes	6	4	1	1
R:R:E98	R:R:M172	5.41	1	Yes	Yes	6	4	1	1
L:L:?1	R:R:E98	4.68	1	Yes	Yes	0	6	0	1
R:R:C99	R:R:Y157	9.41	0	No	Yes	5	4	2	1
R:R:F102	R:R:Y101	13.41	1	Yes	Yes	5	5	1	2
R:R:F169	R:R:Y101	7.22	1	Yes	Yes	4	5	1	2
R:R:F102	R:R:Y157	4.13	1	Yes	Yes	5	4	1	1
R:R:F102	R:R:F169	5.36	1	Yes	Yes	5	4	1	1
L:L:?1	R:R:F102	26.65	1	Yes	Yes	0	5	0	1
R:R:H243	R:R:Y106	5.44	1	Yes	No	8	8	2	1
L:L:?1	R:R:Y106	14.89	1	Yes	No	0	8	0	1
R:R:I156	R:R:L185	4.28	0	No	No	4	5	2	1
R:R:H160	R:R:Y157	11.98	0	Yes	Yes	5	4	2	1
L:L:?1	R:R:Y157	9.93	1	Yes	Yes	0	4	0	1
R:R:H160	R:R:K165	5.24	0	Yes	Yes	5	2	2	2
R:R:H160	R:R:M172	5.25	0	Yes	Yes	5	4	2	1
R:R:H160	R:R:T176	8.21	0	Yes	No	5	2	2	1
R:R:C168	R:R:F169	4.19	0	No	Yes	9	4	2	1
L:L:?1	R:R:F169	10.32	1	Yes	Yes	0	4	0	1
R:R:M172	R:R:W177	4.65	1	Yes	Yes	4	3	1	1
L:L:?1	R:R:M172	14.97	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:T176	8.32	1	Yes	No	0	2	0	1
R:R:F182	R:R:W177	4.01	1	Yes	Yes	5	3	1	1
R:R:Q249	R:R:W177	5.48	1	Yes	Yes	5	3	2	1
R:R:R253	R:R:W177	14.99	0	No	Yes	4	3	2	1
L:L:?1	R:R:W177	21.71	1	Yes	Yes	0	3	0	1
R:R:F182	R:R:F183	9.65	1	Yes	Yes	5	4	1	2
R:R:E186	R:R:F182	8.16	0	No	Yes	5	5	2	1
R:R:F182	R:R:F250	24.65	1	Yes	No	5	5	1	2
L:L:?1	R:R:F182	4.3	1	Yes	Yes	0	5	0	1
R:R:F183	R:R:F250	8.57	1	Yes	No	4	5	2	2
L:L:?1	R:R:L185	4.88	1	Yes	No	0	5	0	1
R:R:E186	R:R:H243	11.08	0	No	Yes	5	8	2	2
R:R:H243	R:R:V242	4.15	1	Yes	Yes	8	7	2	2
R:R:F246	R:R:V242	3.93	1	Yes	Yes	6	7	1	2
R:R:F246	R:R:H243	5.66	1	Yes	Yes	6	8	1	2
R:R:F246	R:R:L270	4.87	1	Yes	No	6	5	1	2
R:R:F246	R:R:M274	6.22	1	Yes	No	6	6	1	1
L:L:?1	R:R:F246	12.04	1	Yes	Yes	0	6	0	1
R:R:L270	R:R:Q249	3.99	0	No	Yes	5	5	2	2
L:L:?1	R:R:M274	6.99	1	Yes	No	0	6	0	1
R:R:T95	R:R:Y157	3.75	0	No	Yes	7	4	2	1
R:R:L185	R:R:V181	2.98	0	No	No	5	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9GE2_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.92
Number of Linked Nodes	285
Number of Links	326
Number of Hubs	45
Number of Links mediated by Hubs	168
Number of Communities	7
Number of Nodes involved in Communities	55
Number of Links involved in Communities	77

Path Summary
Number Of Nodes in MetaPath	56
Number Of Links MetaPath	55
Number of Shortest Paths	70509
Length Of Smallest Path	3
Average Path Length	15.4811
Length of Longest Path	35
Minimum Path Strength	1.38
Average Path Strength	8.11652
Maximum Path Strength	32.44
Minimum Path Correlation	0.7
Average Path Correlation	0.928717
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	46.4459
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.1773
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cannabinoid receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • positive regulation of cell communication • small GTPase-mediated signal transduction • positive regulation of signal transduction • regulation of small GTPase mediated signal transduction • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • Rho protein signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • regulation of response to stimulus • regulation of cell communication • positive regulation of small GTPase mediated signal transduction • positive regulation of signaling • myeloid leukocyte differentiation • regulation of leukocyte differentiation • multicellular organismal process • cellular developmental process • regulation of developmental process • negative regulation of biological process • cell development • regulation of cell differentiation • regulation of cell development • regulation of osteoclast differentiation • multicellular organism development • cell differentiation • osteoclast differentiation • anatomical structure development • negative regulation of cellular process • regulation of immune system process • regulation of multicellular organismal process • negative regulation of cell differentiation • negative regulation of hemopoiesis • developmental process • regulation of multicellular organismal development • negative regulation of leukocyte differentiation • hemopoiesis • regulation of myeloid cell differentiation • negative regulation of developmental process • regulation of myeloid leukocyte differentiation • negative regulation of myeloid cell differentiation • negative regulation of osteoclast differentiation • negative regulation of myeloid leukocyte differentiation • negative regulation of cell development • myeloid cell differentiation • negative regulation of immune system process • immune system process • regulation of hemopoiesis • negative regulation of multicellular organismal process • leukocyte differentiation • positive regulation of ERK1 and ERK2 cascade • positive regulation of MAPK cascade • regulation of MAPK cascade • MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • phospholipase C-activating G protein-coupled receptor signaling pathway • multicellular organismal-level homeostasis • homeostatic process • tissue remodeling • bone remodeling • anatomical structure homeostasis • tissue homeostasis • bone resorption • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • signaling receptor binding • G protein-coupled receptor binding • D5 dopamine receptor binding • dopamine receptor binding • GTPase regulator activity • enzyme regulator activity • guanyl-nucleotide exchange factor activity • nucleoside-triphosphatase regulator activity • molecular function regulator activity • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cation binding • metal ion binding • system process • circulatory system process • regulation of blood pressure • regulation of biological quality • blood circulation • regulation of cell motility • regulation of fibroblast migration • fibroblast migration • regulation of locomotion • ameboidal-type cell migration • regulation of cell migration • cell migration • cell motility • locomotion • embryo development ending in birth or egg hatching • chordate embryonic development • embryo development • in utero embryonic development • regulation of cell shape • cell morphogenesis • regulation of cell morphogenesis • anatomical structure morphogenesis • regulation of anatomical structure morphogenesis • regulation of body fluid levels • wound healing • cell activation • hemostasis • blood coagulation • response to stress • coagulation • response to wounding • platelet activation • branching morphogenesis of an epithelial tube • angiogenesis • tube morphogenesis • epithelial tube morphogenesis • blood vessel development • system development • epithelium development • blood vessel morphogenesis • tube development • morphogenesis of an epithelium • tissue development • vasculature development • circulatory system development • branching involved in blood vessel morphogenesis • tissue morphogenesis • morphogenesis of a branching structure • anatomical structure formation involved in morphogenesis • morphogenesis of a branching epithelium • regulation of cellular component organization • cellular component organization • cellular component biogenesis • cellular component assembly • regulation of postsynapse assembly • cell junction assembly • regulation of synapse structure or activity • synapse organization • cellular component organization or biogenesis • regulation of synapse assembly • postsynapse organization • postsynapse assembly • regulation of postsynapse organization • nervous system development • regulation of cellular component biogenesis • regulation of cell junction assembly • regulation of synapse organization • cell junction organization • synapse assembly • Rho-activating G protein-coupled receptor signaling pathway • anchoring junction • focal adhesion • cell-substrate junction • pigment granule • intracellular vesicle • melanosome • cytoplasmic vesicle • brush border membrane • cluster of actin-based cell projections • brush border • apical part of cell • plasma membrane region • apical plasma membrane • cell projection membrane • postsynapse • nucleus
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	A1I
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	A1I
Name	N-(cyclopent-3-ene-1-carbonyl)-L-histidine
Synonyms
Identifier
Formula	C12 H15 N3 O3
Molecular Weight	249.266
SMILES
PubChem	64766902
Formal Charge	0
Total Atoms	33
Total Chiral Atoms	1
Total Bonds	34
Total Aromatic Bonds	5


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9Y2T6
Sequence	>9GE2_nogp_Chain_R D C L F D G V N E L M K T L Q F A V H I P T F V L G L L L N L L A I H G F S T F L K N R W P D Y A A T S I Y M I N L A V F D L L L V L S L P F K M V L S Q V Q S P F P S L C T L V E C L Y F V S M Y G S V F T I C F I S M D R F L A I R Y P L L V S H L R S P R K I F G I C C T I W V L V W T G S I P I Y S F H G K V E K Y M C F H N M S D D T W S A K V F F P L E V F G F L L P M G I M G F C C S R S I H I L L G R R D H T Q D W V Q Q K A C I Y S I A A S L A V F V V S F L P V H L G F F L Q F L V R N S F I V E C R A K Q S I S F F L Q L S M C F S N V N C C L D V F C Y Y F V I K E F R M N I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZX4	A	Lipid	GPR55	GPR55	Homo sapiens	Lysophosphatidylinositol	-	chim(NtGi1-G13)/β1/γ2	3.03	2024-11-13	doi.org/10.1038/s41422-024-01044-w
	8ZX4 (No Gprot)	A	Lipid	GPR55	GPR55	Homo sapiens	Lysophosphatidylinositol	-		3.03	2024-11-13	doi.org/10.1038/s41422-024-01044-w
	8ZX5	A	Lipid	GPR55	GPR55	Homo sapiens	AM251	-	chim(NtGi1-G13)/β1/γ2	2.85	2024-11-13	doi.org/10.1038/s41422-024-01044-w
	8ZX5 (No Gprot)	A	Lipid	GPR55	GPR55	Homo sapiens	AM251	-		2.85	2024-11-13	doi.org/10.1038/s41422-024-01044-w
	9IYA	A	Lipid	GPR55	GPR55	Homo sapiens	ONO-9710531	-	-	3.04	2025-01-01	doi.org/10.1038/s41422-024-01046-8
	9IY8	A	Orphan	Orphan	GPR55	Homo sapiens	-	-	chim(NtGi1-G13)/β1/γ2	3.01	2025-01-01	doi.org/10.1038/s41422-024-01046-8
	9IY8 (No Gprot)	A	Orphan	Orphan	GPR55	Homo sapiens	-	-		3.01	2025-01-01	doi.org/10.1038/s41422-024-01046-8
	9GE2	A	Orphan	Orphan	GPR55	Homo sapiens	ML184	-	chim(NtGi1-G13)/β1/γ2	2.51	2025-03-05	doi.org/10.1038/s41467-025-57204-y
	9GE2 (No Gprot)	A	Orphan	Orphan	GPR55	Homo sapiens	ML184	-		2.51	2025-03-05	doi.org/10.1038/s41467-025-57204-y
	9GE3	A	Orphan	Orphan	GPR55	Homo sapiens	Lysophosphatidylinositol	-	chim(NtGi1-G13)/β1/γ2	2.87	2025-03-05	doi.org/10.1038/s41467-025-57204-y
	9GE3 (No Gprot)	A	Orphan	Orphan	GPR55	Homo sapiens	Lysophosphatidylinositol	-		2.87	2025-03-05	doi.org/10.1038/s41467-025-57204-y

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