psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:N281	R:R:S41	5.96	No	No	0	4	5
2	R:R:D42	R:R:G43	5.03	No	No	0	3	5
3	R:R:L44	R:R:L48	5.54	No	No	0	5	6
4	R:R:F45	R:R:N91	13.29	No	Yes	4	6	7
5	R:R:F45	R:R:T95	3.89	No	No	0	6	5
6	R:R:F45	R:R:L284	6.09	No	No	4	6	4
7	R:R:L46	R:R:V92	7.45	No	No	0	5	6
8	R:R:L46	R:R:T95	5.9	No	No	0	5	5
9	R:R:I288	R:R:L48	4.28	No	No	0	6	6
10	R:R:I292	R:R:L48	5.71	No	No	0	5	6
11	R:R:G49	R:R:S52	3.71	No	No	5	6	8
12	R:R:G49	R:R:S88	3.71	No	Yes	5	6	9
13	R:R:L50	R:R:V51	4.47	No	No	0	5	5
14	R:R:I292	R:R:V51	3.07	No	No	0	5	5
15	R:R:S52	R:R:S88	6.52	No	Yes	5	8	9
16	R:R:A291	R:R:S52	3.42	No	No	0	9	8
17	R:R:L53	R:R:L85	4.15	Yes	No	0	5	7
18	R:R:L53	R:R:S88	3	Yes	Yes	0	5	9
19	R:R:E55	R:R:F300	7	No	No	0	8	5
20	R:R:N56	R:R:V60	4.43	No	No	0	9	7
21	R:R:A81	R:R:N56	4.69	No	No	0	9	9
22	R:R:L85	R:R:N56	17.85	No	No	0	7	9
23	R:R:F300	R:R:L58	3.65	No	No	0	5	7
24	R:R:A81	R:R:V59	3.39	No	No	0	9	9
25	R:R:A299	R:R:V59	3.39	No	No	0	8	9
26	R:R:F300	R:R:V59	5.24	No	No	0	5	9
27	R:R:C78	R:R:V60	5.12	No	No	0	6	7
28	R:R:T308	R:R:T62	3.14	No	No	0	8	8
29	R:R:C78	R:R:I63	4.91	No	No	0	6	8
30	R:R:N66	R:R:N68	14.98	No	No	0	8	7
31	R:R:H70	R:R:R67	14.67	No	No	0	8	7
32	R:R:L69	R:R:N68	8.24	No	No	0	8	7
33	R:R:L69	R:R:Y74	14.07	No	Yes	0	8	8
34	R:R:E304	R:R:L69	7.95	No	No	0	7	8
35	R:R:H70	R:R:L158	19.28	No	Yes	1	8	3
36	R:R:H70	R:R:R162	10.16	No	No	1	8	1
37	R:R:P72	R:R:S71	3.56	Yes	No	0	7	7
38	R:R:S71	R:R:Y74	5.09	No	Yes	0	7	8
39	R:R:P72	R:R:Y152	4.17	Yes	Yes	1	7	8
40	R:R:P72	R:R:V156	3.53	Yes	No	1	7	7
41	R:R:L158	R:R:P72	3.28	Yes	Yes	1	3	7
42	R:R:A161	R:R:P72	3.74	No	Yes	0	6	7
43	R:R:D141	R:R:M73	11.09	No	No	1	9	8
44	R:R:M73	R:R:S145	3.07	No	No	0	8	9
45	R:R:M73	R:R:Y152	9.58	No	Yes	1	8	8
46	R:R:S302	R:R:Y74	5.09	No	Yes	6	8	8
47	R:R:L305	R:R:Y74	4.69	No	Yes	6	8	8
48	R:R:C75	R:R:R162	5.57	No	No	0	4	1
49	R:R:A137	R:R:F76	4.16	No	No	0	7	7
50	R:R:C79	R:R:F134	8.38	No	Yes	3	9	8
51	R:R:C79	R:R:V165	8.54	No	No	0	9	7
52	R:R:C79	R:R:W169	5.22	No	Yes	3	9	9
53	R:R:D84	R:R:L80	9.5	Yes	No	0	9	9
54	R:R:F134	R:R:L80	4.87	Yes	No	0	8	9
55	R:R:L82	R:R:W169	3.42	No	Yes	0	6	9
56	R:R:S130	R:R:S83	6.52	No	No	3	7	8
57	R:R:F134	R:R:S83	5.28	Yes	No	3	8	8
58	R:R:S83	R:R:W169	4.94	No	Yes	3	8	9
59	R:R:D84	R:R:S131	4.42	Yes	No	0	9	9
60	R:R:A291	R:R:D84	4.63	No	Yes	0	9	9
61	R:R:D84	R:R:P295	3.22	Yes	No	0	9	9
62	R:R:I123	R:R:L86	4.28	Yes	No	7	4	7
63	R:R:L86	R:R:S126	3	No	No	7	7	5
64	R:R:L86	R:R:S127	4.5	No	No	0	7	7
65	R:R:S127	R:R:V87	8.08	No	No	0	7	8
66	R:R:G89	R:R:S88	3.71	No	Yes	0	3	9
67	R:R:I123	R:R:S90	12.39	Yes	No	0	4	5
68	R:R:S90	R:R:T124	6.4	No	No	0	5	5
69	R:R:N91	R:R:T124	5.85	Yes	No	0	7	5
70	R:R:L284	R:R:N91	12.36	No	Yes	4	4	7
71	R:R:I288	R:R:N91	7.08	No	Yes	0	6	7
72	R:R:E94	R:R:I120	16.4	No	Yes	0	4	5
73	R:R:L99	R:R:T95	4.42	No	No	0	4	5
74	R:R:L116	R:R:V97	5.96	No	No	0	3	4
75	R:R:R109	R:R:V112	6.54	No	No	0	3	3
76	R:R:Q114	R:R:Q115	11.52	No	No	0	2	1
77	R:R:A181	R:R:N118	4.69	No	No	0	3	4
78	R:R:D121	R:R:I180	9.8	No	Yes	0	5	5
79	R:R:I180	R:R:V122	4.61	Yes	No	0	5	5
80	R:R:I123	R:R:S126	3.1	Yes	No	7	4	5
81	R:R:C125	R:R:S176	6.89	No	No	0	4	7
82	R:R:C125	R:R:F179	8.38	No	Yes	8	4	5
83	R:R:C125	R:R:I180	3.27	No	Yes	8	4	5
84	R:R:S126	R:R:S176	3.26	No	No	0	5	7
85	R:R:M128	R:R:W254	3.49	No	Yes	0	5	7
86	R:R:F257	R:R:M128	3.73	No	No	0	5	5
87	R:R:I287	R:R:M128	7.29	No	No	0	7	5
88	R:R:F195	R:R:L129	3.65	No	No	0	4	5
89	R:R:S130	R:R:W169	7.41	No	Yes	3	7	9
90	R:R:S130	R:R:S172	3.26	No	No	0	7	7
91	R:R:S131	R:R:W254	4.94	No	Yes	0	9	7
92	R:R:F195	R:R:L132	7.31	No	No	0	4	7
93	R:R:L132	R:R:M199	14.14	No	No	0	7	7
94	R:R:L132	R:R:W254	3.42	No	Yes	0	7	7
95	R:R:C133	R:R:I168	3.27	No	No	0	4	6
96	R:R:F134	R:R:I168	10.05	Yes	No	0	8	6
97	R:R:F134	R:R:W169	13.03	Yes	Yes	3	8	9
98	R:R:D294	R:R:L135	8.14	No	No	2	9	8
99	R:R:L135	R:R:Y298	4.69	No	Yes	2	8	9
100	R:R:I138	R:R:R142	5.01	No	No	2	9	9
101	R:R:I138	R:R:Y298	4.84	No	Yes	2	9	9
102	R:R:A139	R:R:Y207	5.34	No	Yes	0	9	8
103	R:R:I144	R:R:V140	3.07	No	No	0	6	6
104	R:R:D141	R:R:Y152	10.34	No	Yes	1	9	8
105	R:R:R142	R:R:Y207	7.2	No	Yes	2	9	8
106	R:R:R142	R:R:Y298	6.17	No	Yes	2	9	9
107	R:R:F147	R:R:Y143	20.63	Yes	Yes	10	6	7
108	R:R:L206	R:R:Y143	10.55	No	Yes	0	5	7
109	R:R:H209	R:R:Y143	7.62	No	Yes	10	6	7
110	R:R:M210	R:R:Y143	5.99	No	Yes	0	9	7
111	R:R:I144	R:R:Y148	3.63	No	No	0	6	6
112	R:R:F147	R:R:I146	5.02	Yes	No	0	6	8
113	R:R:I146	R:R:M210	7.29	No	No	0	8	9
114	R:R:F147	R:R:H209	10.18	Yes	No	10	6	6
115	R:R:F147	R:R:R213	3.21	Yes	No	0	6	6
116	R:R:H153	R:R:Y152	4.36	No	Yes	0	5	8
117	R:R:V156	R:R:Y152	10.09	No	Yes	1	7	8
118	R:R:I155	R:R:V156	3.07	No	No	0	5	7
119	R:R:P159	R:R:T157	10.49	No	No	0	4	8
120	R:R:L158	R:R:R162	4.86	Yes	No	1	3	1
121	R:R:A164	R:R:R163	4.15	No	No	0	6	3
122	R:R:S172	R:R:V173	3.23	No	No	0	7	3
123	R:R:F179	R:R:I180	21.35	Yes	Yes	8	5	5
124	R:R:F179	R:R:V188	5.24	Yes	No	0	5	4
125	R:R:F179	R:R:L189	3.65	Yes	Yes	0	5	4
126	R:R:H185	R:R:Y182	4.36	Yes	No	0	4	4
127	R:R:D184	R:R:Y183	6.9	No	No	0	4	3
128	R:R:D184	R:R:L189	5.43	No	Yes	0	4	4
129	R:R:H185	R:R:V186	5.54	Yes	No	0	4	1
130	R:R:L189	R:R:L261	4.15	Yes	No	0	4	5
131	R:R:L189	R:R:V265	4.47	Yes	No	0	4	4
132	R:R:F196	R:R:F250	3.22	No	Yes	9	7	8
133	R:R:F196	R:R:W254	9.02	No	Yes	9	7	7
134	R:R:F196	R:R:F258	21.43	No	Yes	0	7	5
135	R:R:F258	R:R:L197	3.65	Yes	No	0	5	4
136	R:R:F250	R:R:M199	6.22	Yes	No	0	8	7
137	R:R:F250	R:R:L200	9.74	Yes	No	0	8	5
138	R:R:M203	R:R:Y207	4.79	No	Yes	2	8	8
139	R:R:M203	R:R:Y298	3.59	No	Yes	2	8	9
140	R:R:A204	R:R:L247	3.15	No	Yes	0	4	7
141	R:R:L246	R:R:Y207	5.86	No	Yes	2	8	8
142	R:R:L247	R:R:Y207	3.52	Yes	Yes	0	7	8
143	R:R:Y207	R:R:Y298	4.96	Yes	Yes	2	8	9
144	R:R:L243	R:R:V208	5.96	No	No	0	8	4
145	R:R:C215	R:R:L211	3.17	No	Yes	0	5	6
146	R:R:L211	R:R:L243	4.15	Yes	No	0	6	8
147	R:R:Q216	R:R:R213	4.67	No	No	0	4	6
148	R:R:H217	R:R:R213	7.9	No	No	0	8	6
149	R:R:K238	R:R:V241	6.07	No	No	0	8	7
150	R:R:K238	R:R:T242	3	No	No	0	8	9
151	R:R:G239	R:R:T242	3.64	No	No	0	8	9
152	R:R:I245	R:R:V241	3.07	No	No	0	7	7
153	R:R:L243	R:R:L247	4.15	No	Yes	0	8	7
154	R:R:L246	R:R:Y298	7.03	No	Yes	2	8	9
155	R:R:I249	R:R:I293	4.42	No	No	0	6	5
156	R:R:F250	R:R:W254	18.04	Yes	Yes	9	8	7
157	R:R:C253	R:R:N290	9.45	No	No	0	8	9
158	R:R:N290	R:R:W254	18.08	No	Yes	0	9	7
159	R:R:G255	R:R:P256	4.06	No	No	0	5	9
160	R:R:F283	R:R:P256	10.11	No	No	0	5	9
161	R:R:L286	R:R:P256	3.28	No	No	0	7	9
162	R:R:F257	R:R:L261	10.96	No	No	0	5	5
163	R:R:F257	R:R:F280	5.36	No	No	0	5	4
164	R:R:F258	R:R:T262	3.89	Yes	No	0	5	4
165	R:R:H260	R:R:L261	5.14	Yes	No	0	4	5
166	R:R:F277	R:R:H260	24.89	Yes	Yes	0	3	4
167	R:R:F280	R:R:H260	19.23	No	Yes	0	4	4
168	R:R:F283	R:R:H260	6.79	No	Yes	0	5	4
169	R:R:C273	R:R:L263	6.35	No	No	0	4	4
170	R:R:F277	R:R:L263	4.87	Yes	No	0	3	4
171	R:R:F277	R:R:I264	6.28	Yes	No	0	3	4
172	R:R:C267	R:R:H270	4.42	No	No	11	3	4
173	R:R:C267	R:R:C273	5.46	No	No	11	3	4
174	R:R:E269	R:R:P268	6.29	No	No	0	1	3
175	R:R:H270	R:R:P271	3.05	No	No	0	4	3
176	R:R:C273	R:R:H270	5.9	No	No	11	4	4
177	R:R:F277	R:R:G274	4.52	Yes	No	0	3	2
178	R:R:C289	R:R:I292	3.27	No	No	0	4	5
179	R:R:D294	R:R:N290	6.73	No	No	0	9	9
180	R:R:D294	R:R:Y298	3.45	No	Yes	2	9	9
181	R:R:I297	R:R:Y298	6.04	No	Yes	0	8	9
182	R:R:H301	R:R:R306	3.39	No	No	0	7	9
183	R:R:E304	R:R:S302	7.19	No	No	0	7	8
184	R:R:L305	R:R:S302	4.5	No	No	6	8	8
185	R:R:L93	R:R:V97	2.98	No	No	0	8	4
186	R:R:L206	R:R:V140	2.98	No	No	0	5	6
187	R:R:N118	R:R:V122	2.96	No	No	0	4	5
188	R:R:L58	R:R:T62	2.95	No	No	0	7	8
189	R:R:L305	R:R:T62	2.95	No	No	0	8	8
190	R:R:I293	R:R:I297	2.94	No	No	0	5	8
191	R:R:I120	R:R:L116	2.85	Yes	No	0	5	3
192	R:R:I245	R:R:L246	2.85	No	No	0	7	8
193	R:R:I276	R:R:L263	2.85	No	No	0	4	4
194	R:R:D117	R:R:I120	2.8	No	Yes	0	6	5
195	R:R:A164	R:R:F76	2.77	No	No	0	6	7
196	R:R:H185	R:R:V188	2.77	Yes	No	0	4	4
197	R:R:H225	R:R:I221	2.65	No	No	0	4	7
198	R:R:F76	R:R:V165	2.62	No	No	0	7	7
199	R:R:F258	R:R:V193	2.62	Yes	No	0	5	4
200	R:R:F175	R:R:L129	2.44	No	No	0	4	5
201	R:R:F195	R:R:L192	2.44	No	No	0	4	5
202	R:R:F251	R:R:L200	2.44	No	No	0	6	5
203	R:R:F283	R:R:L259	2.44	No	No	0	5	6
204	R:R:M210	R:R:Y207	2.39	No	Yes	0	9	8
205	R:R:A139	R:R:G136	1.95	No	No	0	9	7
206	R:R:G104	R:R:L101	1.71	No	No	0	5	3
207	R:R:G248	R:R:L247	1.71	No	Yes	0	6	7
208	R:R:L158	R:R:P159	1.64	Yes	No	0	3	4
209	R:R:A299	R:R:I77	1.62	No	No	0	8	7
210	R:R:V170	R:R:V174	1.6	No	No	0	4	4
211	R:R:V173	R:R:V174	1.6	No	No	0	3	4
212	R:R:V201	R:R:V205	1.6	No	No	0	4	4
213	R:R:T177	R:R:V122	1.59	No	No	0	4	5
214	R:R:C267	R:R:L266	1.59	No	No	0	3	3
215	R:R:A57	R:R:L53	1.58	No	Yes	0	5	5
216	R:R:A103	R:R:L100	1.58	No	No	0	5	4
217	R:R:A214	R:R:L211	1.58	No	Yes	0	8	6
218	R:R:A240	R:R:L211	1.58	No	Yes	0	7	6
219	R:R:A111	R:R:Q114	1.52	No	No	0	2	2
220	R:R:I276	R:R:T272	1.52	No	No	0	4	4
221	R:R:L44	R:R:S47	1.5	No	No	0	5	3
222	R:R:L53	R:R:V54	1.49	Yes	No	0	5	4
223	R:R:L202	R:R:V201	1.49	No	No	0	5	4
224	R:R:L206	R:R:V205	1.49	No	No	0	5	4
225	R:R:D42	R:R:S41	1.47	No	No	0	3	5
226	R:R:I120	R:R:I123	1.47	Yes	Yes	0	5	4
227	R:R:A187	R:R:H185	1.46	No	Yes	0	4	4
228	R:R:I297	R:R:L296	1.43	No	No	0	8	5
229	R:R:I276	R:R:N279	1.42	No	No	0	4	4
230	R:R:A171	R:R:F175	1.39	No	No	0	3	4
231	R:R:L101	R:R:L113	1.38	No	No	0	3	6
232	R:R:A167	R:R:R163	1.38	No	No	0	3	3
233	R:R:L282	R:R:N279	1.37	No	No	0	3	4
234	R:R:R160	R:R:T157	1.29	No	No	0	7	8
235	R:R:I155	R:R:R151	1.25	No	No	0	5	6
236	R:R:L178	R:R:Y182	1.17	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:L53	2.555	4	0	5
2	R:R:P72	3.656	5	1	7
3	R:R:Y74	7.235	4	6	8
4	R:R:D84	5.4425	4	0	9
5	R:R:S88	4.235	4	5	9
6	R:R:N91	9.645	4	4	7
7	R:R:I120	5.88	4	0	5
8	R:R:I123	5.31	4	7	4
9	R:R:F134	8.322	5	3	8
10	R:R:Y143	11.1975	4	10	7
11	R:R:F147	9.76	4	10	6
12	R:R:Y152	7.708	5	1	8
13	R:R:L158	7.265	4	1	3
14	R:R:W169	6.804	5	3	9
15	R:R:F179	9.655	4	8	5
16	R:R:I180	9.7575	4	8	5
17	R:R:H185	3.5325	4	0	4
18	R:R:L189	4.425	4	0	4
19	R:R:Y207	4.86571	7	2	8
20	R:R:L211	2.62	4	0	6
21	R:R:L247	3.1325	4	0	7
22	R:R:F250	9.305	4	9	8
23	R:R:W254	9.49833	6	9	7
24	R:R:F258	7.8975	4	0	5
25	R:R:H260	14.0125	4	0	4
26	R:R:F277	10.14	4	0	3
27	R:R:Y298	5.09625	8	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I288	R:R:N91	12.9945	7.08	No	Yes	0	6	7
2	R:R:I288	R:R:L48	11.4247	4.28	No	No	0	6	6
3	R:R:A291	R:R:S52	68.4294	3.42	No	No	0	9	8
4	R:R:A291	R:R:D84	69.5077	4.63	No	Yes	0	9	9
5	R:R:D84	R:R:S131	91.9765	4.42	Yes	No	0	9	9
6	R:R:S131	R:R:W254	92.6267	4.94	No	Yes	0	9	7
7	R:R:M128	R:R:W254	100	3.49	No	Yes	0	5	7
8	R:R:F257	R:R:M128	99.1279	3.73	No	No	0	5	5
9	R:R:F257	R:R:L261	76.2229	10.96	No	No	0	5	5
10	R:R:L189	R:R:L261	61.0323	4.15	Yes	No	0	4	5
11	R:R:F179	R:R:L189	57.0602	3.65	Yes	Yes	0	5	4
12	R:R:C125	R:R:F179	41.4969	8.38	No	Yes	8	4	5
13	R:R:C125	R:R:S176	41.6871	6.89	No	No	0	4	7
14	R:R:S126	R:R:S176	40.4503	3.26	No	No	0	5	7
15	R:R:I123	R:R:S126	34.7736	3.1	Yes	No	7	4	5
16	R:R:I123	R:R:S90	26.219	12.39	Yes	No	0	4	5
17	R:R:S90	R:R:T124	24.7919	6.4	No	No	0	5	5
18	R:R:N91	R:R:T124	23.3489	5.85	Yes	No	0	7	5
19	R:R:S52	R:R:S88	65.8686	6.52	No	Yes	5	8	9
20	R:R:L53	R:R:S88	63.9578	3	Yes	Yes	0	5	9
21	R:R:L53	R:R:L85	60.4376	4.15	Yes	No	0	5	7
22	R:R:F300	R:R:V59	49.0209	5.24	No	No	0	5	9
23	R:R:A81	R:R:V59	52.9692	3.39	No	No	0	9	9
24	R:R:A81	R:R:N56	54.2535	4.69	No	No	0	9	9
25	R:R:L85	R:R:N56	59.2325	17.85	No	No	0	7	9
26	R:R:F300	R:R:L58	46.3094	3.65	No	No	0	5	7
27	R:R:L58	R:R:T62	44.9298	2.95	No	No	0	7	8
28	R:R:L305	R:R:T62	42.1232	2.95	No	No	0	8	8
29	R:R:L305	R:R:Y74	37.4296	4.69	No	Yes	6	8	8
30	R:R:L158	R:R:P72	14.1996	3.28	Yes	Yes	1	3	7
31	R:R:P72	R:R:S71	30.4051	3.56	Yes	No	0	7	7
32	R:R:S71	R:R:Y74	31.9512	5.09	No	Yes	0	7	8
33	R:R:C79	R:R:V165	10.505	8.54	No	No	0	9	7
34	R:R:C79	R:R:F134	11.7577	8.38	No	Yes	3	9	8
35	R:R:F134	R:R:L80	37.9212	4.87	Yes	No	0	8	9
36	R:R:D84	R:R:L80	39.38	9.5	Yes	No	0	9	9
37	R:R:F134	R:R:W169	11.7022	13.03	Yes	Yes	3	8	9
38	R:R:F134	R:R:S83	10.0848	5.28	Yes	No	3	8	8
39	R:R:L132	R:R:W254	12.3048	3.42	No	Yes	0	7	7
40	R:R:S130	R:R:S172	13.7239	3.26	No	No	0	7	7
41	R:R:D294	R:R:N290	67.9854	6.73	No	No	0	9	9
42	R:R:N290	R:R:W254	70.1261	18.08	No	Yes	0	9	7
43	R:R:D294	R:R:Y298	65.4246	3.45	No	Yes	2	9	9
44	R:R:Y207	R:R:Y298	46.8802	4.96	Yes	Yes	2	8	9
45	R:R:L206	R:R:Y143	12.3127	10.55	No	Yes	0	5	7
46	R:R:M210	R:R:Y143	21.9773	5.99	No	Yes	0	9	7
47	R:R:M210	R:R:Y207	31.856	2.39	No	Yes	0	9	8
48	R:R:F147	R:R:R213	10.4099	3.21	Yes	No	0	6	6
49	R:R:S172	R:R:V173	10.3148	3.23	No	No	0	7	3
50	R:R:L247	R:R:Y207	15.9042	3.52	Yes	Yes	0	7	8
51	R:R:L243	R:R:L247	10.7429	4.15	No	Yes	0	8	7
52	R:R:F283	R:R:H260	13.8032	6.79	No	Yes	0	5	4
53	R:R:H260	R:R:L261	28.9939	5.14	Yes	No	0	4	5
54	R:R:F257	R:R:F280	23.0635	5.36	No	No	0	5	4
55	R:R:F280	R:R:H260	22.1121	19.23	No	Yes	0	4	4
56	R:R:F277	R:R:H260	35.1701	24.89	Yes	Yes	0	3	4
57	R:R:C273	R:R:L263	13.8904	6.35	No	No	0	4	4
58	R:R:F277	R:R:L263	27.3924	4.87	Yes	No	0	3	4
59	R:R:I276	R:R:L263	11.1393	2.85	No	No	0	4	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9K3P_nogp

PDB Summary
PDB	9K3P_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3
Number of Linked Nodes	222
Number of Links	236
Number of Hubs	27
Number of Links mediated by Hubs	109
Number of Communities	11
Number of Nodes involved in Communities	45
Number of Links involved in Communities	53

Path Summary
Number Of Nodes in MetaPath	60
Number Of Links MetaPath	59
Number of Shortest Paths	24691
Length Of Smallest Path	3
Average Path Length	15.5464
Length of Longest Path	39
Minimum Path Strength	1.395
Average Path Strength	6.26289
Maximum Path Strength	18.06
Minimum Path Correlation	0.7
Average Path Correlation	0.936476
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	52.5381
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	33.8838
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q01726
Sequence	>9K3P_nogp_Chain_R S D G L F L S L G L V S L V E N A L V V A T I A K N R N L H S P M Y C F I C C L A L S D L L V S G S N V L E T A V I L L L E A G A L V A R A A V L Q Q L D N V I D V I T C S S M L S S L C F L G A I A V D R Y I S I F Y A L R Y H S I V T L P R A R R A V A A I W V A S V V F S T L F I A Y Y D H V A V L L C L V V F F L A M L V L M A V L Y V H M L A R A C Q H A Q G I A R L H L K G A V T L T I L L G I F F L C W G P F F L H L T L I V L C P E H P T C G C I F K N F N L F L A L I I C N A I I D P L I Y A F H S Q E L R R T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7F4D	A	Peptide	Melanocortin	MC₁	Homo sapiens	α-MSH	-	chim(NtGi1-Gs)/β1/γ2	3	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4D (No Gprot)	A	Peptide	Melanocortin	MC₁	Homo sapiens	α-MSH	-		3	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4F	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-	chim(NtGi1-Gs)/β1/γ2	2.9	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4F (No Gprot)	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-		2.9	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4H	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-	chim(NtGi1-Gs)/β1/γ2	2.7	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4H (No Gprot)	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-		2.7	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4I	A	Peptide	Melanocortin	MC₁	Homo sapiens	SHU9119	-	chim(NtGi1-Gs)/β1/γ2	3.1	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	7F4I (No Gprot)	A	Peptide	Melanocortin	MC₁	Homo sapiens	SHU9119	-		3.1	2021-09-08	doi.org/10.1038/s41422-021-00557-y
	9K3P	A	Peptide	Melanocortin	MC₁	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-08-06	doi.org/10.1016/j.str.2025.03.004
	9K3P (No Gprot)	A	Peptide	Melanocortin	MC₁	Homo sapiens	-	-		2.98	2025-08-06	doi.org/10.1016/j.str.2025.03.004

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9K3P_nogp.zip

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