psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:S1	R:R:Q194	4.33	No	No	0	0	5
2	L:L:S1	R:R:Y251	5.09	No	Yes	0	0	7
3	L:L:D5	L:L:L2	6.79	Yes	No	0	0	0
4	L:L:L2	R:R:W86	4.56	No	Yes	0	0	7
5	L:L:L2	R:R:T105	10.32	No	No	0	0	5
6	L:L:A3	R:R:W86	6.48	No	Yes	0	0	7
7	L:L:A4	R:R:M279	4.83	No	Yes	0	0	5
8	L:L:D5	L:L:S31	4.42	Yes	No	3	0	0
9	L:L:D5	L:L:Q33	10.44	Yes	Yes	3	0	0
10	L:L:D5	R:R:S179	4.42	Yes	No	3	0	3
11	L:L:T6	R:R:K26	7.51	No	No	0	0	1
12	L:L:T6	R:R:Q280	7.09	No	No	0	0	3
13	L:L:C10	L:L:P7	3.77	No	Yes	0	0	0
14	L:L:P7	L:L:S31	5.34	Yes	No	0	0	0
15	L:L:P7	L:L:Q33	4.74	Yes	Yes	0	0	0
16	L:L:F28	L:L:T8	3.89	Yes	No	1	0	0
17	L:L:T8	R:R:E172	14.11	No	Yes	1	0	2
18	L:L:T8	R:R:H175	4.11	No	No	1	0	1
19	L:L:A9	R:R:P19	3.74	No	Yes	1	0	4
20	L:L:A9	R:R:Q21	4.55	No	No	1	0	1
21	L:L:C10	L:L:C34	7.28	No	No	0	0	0
22	L:L:C11	L:L:C50	7.28	No	No	1	0	0
23	L:L:C11	R:R:P19	3.77	No	Yes	1	0	4
24	L:L:F12	L:L:S35	6.61	Yes	No	0	0	0
25	L:L:F12	L:L:K36	3.72	Yes	No	0	0	0
26	L:L:F12	R:R:S272	3.96	Yes	No	0	0	3
27	L:L:S13	R:R:S17	6.52	No	No	0	0	4
28	L:L:K36	L:L:Y14	10.75	No	No	0	0	0
29	L:L:D52	L:L:Y14	26.44	No	No	0	0	0
30	L:L:Q18	L:L:W57	23	No	Yes	4	0	0
31	L:L:Q18	L:L:Y61	5.64	No	Yes	4	0	0
32	L:L:I19	L:L:V49	4.61	No	No	0	0	0
33	L:L:N22	L:L:P20	6.52	No	No	8	0	0
34	L:L:F23	L:L:P20	7.22	No	No	8	0	0
35	L:L:Q21	L:L:Y61	4.51	No	Yes	0	0	0
36	L:L:F23	L:L:N22	8.46	No	No	8	0	0
37	L:L:F41	L:L:I24	8.79	No	No	0	0	0
38	L:L:I24	L:L:Y61	4.84	No	Yes	0	0	0
39	L:L:D26	R:R:K171	4.15	No	No	0	0	2
40	L:L:V62	L:L:Y27	3.79	No	No	0	0	0
41	L:L:L65	L:L:Y27	7.03	No	No	0	0	0
42	L:L:E66	L:L:Y27	10.1	No	No	0	0	0
43	L:L:F28	L:L:I40	6.28	Yes	Yes	1	0	0
44	L:L:F28	R:R:Q170	10.54	Yes	No	1	0	1
45	L:L:F28	R:R:E172	11.66	Yes	Yes	1	0	2
46	L:L:E29	R:R:R168	6.98	No	No	1	0	4
47	L:L:E29	R:R:Q170	6.37	No	No	1	0	1
48	L:L:E29	R:R:H181	9.85	No	No	1	0	4
49	L:L:C34	L:L:T30	5.07	No	No	0	0	0
50	L:L:S31	R:R:S179	6.52	No	No	3	0	3
51	L:L:S32	R:R:S180	4.89	No	No	0	0	4
52	L:L:S32	R:R:F182	6.61	No	Yes	0	0	5
53	L:L:Q33	R:R:N258	10.56	Yes	No	3	0	4
54	L:L:Q33	R:R:M279	5.44	Yes	Yes	3	0	5
55	L:L:S35	R:R:Q261	8.66	No	Yes	0	0	4
56	L:L:P37	R:R:Y187	15.3	No	No	0	0	3
57	L:L:G38	L:L:P53	4.06	No	No	0	0	0
58	L:L:F41	L:L:V39	6.55	No	No	0	0	0
59	L:L:I40	L:L:Q48	6.86	Yes	Yes	1	0	0
60	L:L:I40	R:R:P19	5.08	Yes	Yes	1	0	4
61	L:L:L42	L:L:Q48	9.32	No	Yes	0	0	0
62	L:L:R47	L:L:S46	10.54	No	No	0	0	0
63	L:L:R47	R:R:E18	4.65	No	No	0	0	3
64	L:L:Q48	R:R:P19	6.32	Yes	Yes	1	0	4
65	L:L:Q48	R:R:Q21	6.4	Yes	No	1	0	1
66	L:L:C50	R:R:P19	5.65	No	Yes	1	0	4
67	L:L:A51	L:L:V58	5.09	No	No	0	0	0
68	L:L:D52	L:L:S54	5.89	No	No	0	0	0
69	L:L:D52	L:L:E55	12.99	No	Yes	0	0	0
70	L:L:P53	R:R:Y184	9.74	No	No	0	0	1
71	L:L:E55	L:L:E56	6.34	Yes	No	4	0	0
72	L:L:E55	L:L:W57	18.54	Yes	Yes	4	0	0
73	L:L:E55	L:L:V58	4.28	Yes	No	4	0	0
74	L:L:E56	L:L:W57	6.54	No	Yes	4	0	0
75	L:L:V58	L:L:W57	11.03	No	Yes	4	0	0
76	L:L:W57	L:L:Y61	5.79	Yes	Yes	4	0	0
77	L:L:Q59	R:R:Y184	12.4	No	No	0	0	1
78	L:L:K60	L:L:Y61	8.36	No	Yes	0	0	0
79	L:L:D64	L:L:K60	11.06	No	No	0	0	0
80	R:R:P19	R:R:Q21	4.74	Yes	No	1	4	1
81	R:R:C20	R:R:C269	7.28	No	No	0	9	6
82	R:R:K22	R:R:V25	4.55	Yes	No	9	3	1
83	R:R:K22	R:R:N273	6.99	Yes	No	9	3	1
84	R:R:N24	R:R:Q27	3.96	No	No	0	1	2
85	R:R:N273	R:R:V25	5.91	No	No	9	1	1
86	R:R:I28	R:R:Q27	6.86	No	No	0	2	2
87	R:R:I28	R:R:R31	3.76	No	No	0	2	3
88	R:R:I28	R:R:Q277	8.23	No	No	0	2	1
89	R:R:A29	R:R:Q280	4.55	No	No	0	5	3
90	R:R:L32	R:R:P35	4.93	No	No	0	6	5
91	R:R:L33	R:R:Y37	19.93	No	Yes	0	6	8
92	R:R:A90	R:R:L33	4.73	No	No	0	5	6
93	R:R:P34	R:R:P35	5.84	No	No	0	6	5
94	R:R:L36	R:R:T284	4.42	No	No	0	6	6
95	R:R:A87	R:R:Y37	4	No	Yes	0	6	8
96	R:R:T284	R:R:Y37	8.74	No	Yes	0	6	8
97	R:R:M287	R:R:Y37	8.38	No	Yes	0	8	8
98	R:R:L39	R:R:V40	4.47	No	No	0	5	7
99	R:R:F41	R:R:F45	6.43	No	Yes	0	7	6
100	R:R:F41	R:R:P84	15.89	No	No	0	7	9
101	R:R:F43	R:R:I295	5.02	No	No	0	5	6
102	R:R:F45	R:R:M49	7.46	Yes	No	0	6	3
103	R:R:F45	R:R:L77	4.87	Yes	No	0	6	7
104	R:R:A73	R:R:N48	4.69	No	Yes	0	9	9
105	R:R:D76	R:R:N48	12.12	No	Yes	0	9	9
106	R:R:L77	R:R:N48	4.12	No	Yes	0	7	9
107	R:R:N48	R:R:P294	6.52	Yes	No	0	9	9
108	R:R:F299	R:R:L50	4.87	No	No	0	7	6
109	R:R:L69	R:R:V51	4.47	No	No	0	8	8
110	R:R:F304	R:R:V51	6.55	Yes	No	0	8	8
111	R:R:F304	R:R:I54	11.3	Yes	No	0	8	7
112	R:R:I54	R:R:L308	5.71	No	No	0	7	6
113	R:R:L55	R:R:L61	4.15	Yes	No	11	7	6
114	R:R:D66	R:R:L55	4.07	No	Yes	0	8	7
115	R:R:L55	R:R:L69	5.54	Yes	No	0	7	8
116	R:R:L55	R:R:L70	5.54	Yes	No	11	7	6
117	R:R:I56	R:R:R60	5.01	No	No	0	3	5
118	R:R:F311	R:R:N57	7.25	No	Yes	0	4	4
119	R:R:C58	R:R:Y307	8.06	No	No	0	5	5
120	R:R:D66	R:R:K59	20.74	No	No	0	8	5
121	R:R:K303	R:R:K59	7.18	No	No	12	6	5
122	R:R:K59	R:R:Y307	11.94	No	No	12	5	5
123	R:R:I67	R:R:L61	5.71	No	No	0	7	6
124	R:R:L61	R:R:L70	5.54	No	No	11	6	6
125	R:R:R140	R:R:S63	5.27	Yes	No	0	6	7
126	R:R:M64	R:R:Y68	13.17	No	Yes	2	6	7
127	R:R:D125	R:R:M64	4.16	Yes	No	2	8	6
128	R:R:M64	R:R:R140	4.96	No	Yes	2	6	6
129	R:R:D125	R:R:T65	8.67	Yes	No	2	8	8
130	R:R:R140	R:R:T65	6.47	Yes	No	2	6	8
131	R:R:L121	R:R:Y68	12.89	No	Yes	2	6	7
132	R:R:D125	R:R:Y68	5.75	Yes	Yes	2	8	7
133	R:R:G145	R:R:Y68	4.35	No	Yes	0	7	7
134	R:R:T148	R:R:Y68	8.74	No	Yes	0	6	7
135	R:R:A298	R:R:L69	4.73	No	No	0	7	8
136	R:R:F118	R:R:N71	13.29	Yes	No	2	7	9
137	R:R:N71	R:R:S149	10.43	No	No	2	9	7
138	R:R:N71	R:R:W153	6.78	No	Yes	2	9	9
139	R:R:D76	R:R:L72	6.79	No	No	10	9	9
140	R:R:L72	R:R:N293	9.61	No	Yes	10	9	9
141	R:R:F78	R:R:I74	5.02	Yes	No	0	7	6
142	R:R:S114	R:R:S75	6.52	No	No	2	7	8
143	R:R:S75	R:R:W153	6.18	No	Yes	2	8	9
144	R:R:D76	R:R:N293	12.12	No	Yes	10	9	9
145	R:R:F78	R:R:L107	8.53	Yes	No	0	7	5
146	R:R:F78	R:R:W153	4.01	Yes	Yes	0	7	9
147	R:R:F79	R:R:Y108	18.57	No	Yes	0	7	7
148	R:R:F79	R:R:M287	7.46	No	No	0	7	8
149	R:R:C290	R:R:F79	4.19	No	No	0	8	7
150	R:R:T82	R:R:W86	4.85	Yes	Yes	7	7	7
151	R:R:L104	R:R:T82	5.9	No	Yes	7	5	7
152	R:R:L107	R:R:T82	4.42	No	Yes	0	5	7
153	R:R:T82	R:R:Y108	8.74	Yes	Yes	7	7	7
154	R:R:P84	R:R:V83	7.07	No	No	0	9	7
155	R:R:M287	R:R:V83	6.09	No	No	0	8	7
156	R:R:F85	R:R:F96	6.43	No	Yes	0	6	7
157	R:R:F85	R:R:L104	8.53	No	No	0	6	5
158	R:R:W86	R:R:W94	7.5	Yes	Yes	0	7	9
159	R:R:L104	R:R:W86	14.81	No	Yes	7	5	7
160	R:R:W86	R:R:Y108	5.79	Yes	Yes	7	7	7
161	R:R:D95	R:R:H88	3.78	No	No	0	3	5
162	R:R:W94	R:R:Y89	8.68	Yes	No	0	9	4
163	R:R:T177	R:R:Y89	7.49	No	No	0	2	4
164	R:R:D95	R:R:Q93	6.53	No	No	0	3	3
165	R:R:F96	R:R:W94	20.04	Yes	Yes	0	7	9
166	R:R:C101	R:R:W94	6.53	No	Yes	0	9	9
167	R:R:S169	R:R:W94	4.94	No	Yes	0	4	9
168	R:R:F96	R:R:M100	6.22	Yes	No	0	7	6
169	R:R:N98	R:R:Q102	9.24	No	No	0	3	7
170	R:R:N98	R:R:R168	4.82	No	No	0	3	4
171	R:R:C101	R:R:C178	7.28	No	No	0	9	9
172	R:R:T105	R:R:T167	6.28	No	No	0	5	5
173	R:R:E283	R:R:Y108	8.98	No	Yes	0	6	7
174	R:R:F109	R:R:F113	7.5	No	Yes	13	5	7
175	R:R:F109	R:R:N163	20.54	No	No	0	5	4
176	R:R:I110	R:R:V157	7.68	No	No	0	5	4
177	R:R:I110	R:R:S160	4.64	No	No	0	5	7
178	R:R:F112	R:R:F113	13.93	Yes	Yes	0	7	7
179	R:R:F112	R:R:I116	5.02	Yes	No	0	7	7
180	R:R:F112	R:R:I198	8.79	Yes	No	0	7	5
181	R:R:F112	R:R:W248	5.01	Yes	Yes	0	7	9
182	R:R:F113	R:R:K197	9.93	Yes	No	0	7	3
183	R:R:S114	R:R:W153	8.65	No	Yes	2	7	9
184	R:R:F117	R:R:T152	3.89	No	No	0	5	6
185	R:R:F117	R:R:L201	7.31	No	No	0	5	4
186	R:R:F118	R:R:L121	4.87	Yes	No	2	7	6
187	R:R:F118	R:R:S149	3.96	Yes	No	2	7	7
188	R:R:F118	R:R:T152	12.97	Yes	No	2	7	6
189	R:R:F118	R:R:W153	9.02	Yes	Yes	2	7	9
190	R:R:I119	R:R:Y297	10.88	No	No	0	8	9
191	R:R:I120	R:R:P206	8.47	No	No	0	7	9
192	R:R:I120	R:R:V209	4.61	No	No	0	7	6
193	R:R:L121	R:R:T152	4.42	No	No	2	6	6
194	R:R:T123	R:R:Y214	6.24	No	Yes	0	9	9
195	R:R:D125	R:R:R140	16.68	Yes	Yes	2	8	6
196	R:R:R126	R:R:Y214	8.23	No	Yes	0	9	9
197	R:R:V131	R:R:Y127	10.09	No	No	0	7	8
198	R:R:C213	R:R:Y127	9.41	No	No	0	8	8
199	R:R:I217	R:R:V130	15.36	No	No	0	8	8
200	R:R:T220	R:R:V130	4.76	No	No	0	5	8
201	R:R:H132	R:R:V131	8.3	No	No	0	6	7
202	R:R:F135	R:R:H132	4.53	No	No	0	5	6
203	R:R:F135	R:R:K138	4.96	No	No	0	5	3
204	R:R:A139	R:R:F135	5.55	No	No	0	4	5
205	R:R:F144	R:R:T148	7.78	No	No	0	3	6
206	R:R:F158	R:R:V154	6.55	No	Yes	0	4	4
207	R:R:I164	R:R:L161	4.28	No	No	0	4	4
208	R:R:F166	R:R:I165	3.77	Yes	No	0	5	3
209	R:R:F166	R:R:F182	7.5	Yes	Yes	6	5	5
210	R:R:F166	R:R:P183	7.22	Yes	No	0	5	3
211	R:R:F166	R:R:W190	16.04	Yes	Yes	6	5	3
212	R:R:S180	R:R:T167	6.4	No	No	0	4	5
213	R:R:H181	R:R:R168	16.93	No	No	1	4	4
214	R:R:C178	R:R:S169	5.16	No	No	0	9	4
215	R:R:H181	R:R:Q170	16.07	No	No	1	4	1
216	R:R:K171	R:R:Y176	10.75	No	No	0	2	4
217	R:R:E172	R:R:H175	17.23	Yes	No	1	2	1
218	R:R:F182	R:R:Y187	8.25	Yes	No	0	5	3
219	R:R:F182	R:R:W190	5.01	Yes	Yes	6	5	3
220	R:R:Q186	R:R:S185	4.33	No	No	0	3	3
221	R:R:F189	R:R:Q186	9.37	No	No	6	1	3
222	R:R:Q186	R:R:W190	10.95	No	Yes	6	3	3
223	R:R:K191	R:R:Y187	5.97	No	No	0	4	3
224	R:R:K191	R:R:Q188	4.07	No	No	0	4	2
225	R:R:N192	R:R:Q188	6.6	No	No	0	3	2
226	R:R:F189	R:R:W190	8.02	No	Yes	6	1	3
227	R:R:F193	R:R:W190	7.02	No	Yes	0	3	3
228	R:R:K191	R:R:T259	10.51	No	No	0	4	5
229	R:R:F260	R:R:N192	8.46	No	No	0	5	3
230	R:R:I198	R:R:Q194	4.12	No	No	0	5	5
231	R:R:L255	R:R:T195	4.42	Yes	No	0	6	5
232	R:R:T195	R:R:T259	12.56	No	No	0	5	5
233	R:R:I198	R:R:L255	4.28	No	Yes	0	5	6
234	R:R:N252	R:R:V199	5.91	No	No	0	8	5
235	R:R:L256	R:R:V199	4.47	No	No	0	5	5
236	R:R:G202	R:R:N252	5.09	No	No	0	6	8
237	R:R:L203	R:R:N252	10.98	No	No	0	8	8
238	R:R:L205	R:R:L208	4.15	No	No	0	6	4
239	R:R:P206	R:R:Y244	6.95	No	Yes	0	9	9
240	R:R:M210	R:R:M241	5.78	No	No	0	8	8
241	R:R:M210	R:R:Y244	5.99	No	Yes	0	8	9
242	R:R:I217	R:R:Y214	4.84	No	Yes	0	8	9
243	R:R:I237	R:R:Y214	13.3	No	Yes	0	8	9
244	R:R:M241	R:R:Y214	4.79	No	Yes	0	8	9
245	R:R:L218	R:R:V234	5.96	No	No	0	4	6
246	R:R:I237	R:R:L218	7.14	No	No	0	8	4
247	R:R:C224	R:R:R230	4.18	No	No	0	4	7
248	R:R:K228	R:R:N226	15.39	No	No	14	5	4
249	R:R:K229	R:R:N226	11.19	No	No	14	6	4
250	R:R:E227	R:R:R230	6.98	No	No	0	3	7
251	R:R:K228	R:R:K229	4.31	No	No	14	5	6
252	R:R:R232	R:R:R235	4.26	No	No	0	7	5
253	R:R:F238	R:R:V234	3.93	No	No	0	5	6
254	R:R:L236	R:R:V300	7.45	No	No	0	8	7
255	R:R:I296	R:R:V243	4.61	No	No	0	8	6
256	R:R:W248	R:R:Y244	16.4	Yes	Yes	5	9	9
257	R:R:H289	R:R:Y244	8.71	No	Yes	5	9	9
258	R:R:A249	R:R:F245	8.32	No	No	0	6	5
259	R:R:F247	R:R:L285	9.74	Yes	No	5	8	8
260	R:R:F247	R:R:T288	9.08	Yes	No	5	8	5
261	R:R:F247	R:R:H289	10.18	Yes	No	5	8	9
262	R:R:F247	R:R:I292	3.77	Yes	No	0	8	6
263	R:R:G286	R:R:W248	5.63	No	Yes	0	8	9
264	R:R:H289	R:R:W248	15.87	No	Yes	5	9	9
265	R:R:L255	R:R:Y251	17.58	Yes	Yes	0	6	7
266	R:R:T282	R:R:Y251	8.74	Yes	Yes	0	7	7
267	R:R:E283	R:R:Y251	14.59	No	Yes	0	6	7
268	R:R:M279	R:R:V254	4.56	Yes	No	0	5	5
269	R:R:T282	R:R:V254	6.35	Yes	No	0	7	5
270	R:R:L255	R:R:M279	4.24	Yes	Yes	0	6	5
271	R:R:F264	R:R:L257	6.09	No	No	0	1	4
272	R:R:L257	R:R:L275	5.54	No	No	0	4	5
273	R:R:L275	R:R:N258	6.87	No	No	0	5	4
274	R:R:M279	R:R:N258	5.61	Yes	No	3	5	4
275	R:R:F260	R:R:T259	10.38	No	No	0	5	5
276	R:R:L266	R:R:Q261	3.99	No	Yes	0	4	4
277	R:R:L275	R:R:Q261	3.99	No	Yes	0	5	4
278	R:R:F263	R:R:F264	6.43	No	No	0	1	1
279	R:R:L266	R:R:S271	9.01	No	No	0	4	1
280	R:R:N268	R:R:S270	4.47	No	No	0	4	1
281	R:R:R274	R:R:S271	3.95	No	No	0	2	1
282	R:R:L285	R:R:T288	4.42	No	No	5	8	5
283	R:R:I292	R:R:I295	4.42	No	No	0	6	6
284	R:R:N293	R:R:P294	11.4	Yes	No	0	9	9
285	R:R:N293	R:R:Y297	5.81	Yes	No	0	9	9
286	R:R:F299	R:R:I295	6.28	No	No	0	7	6
287	R:R:I296	R:R:Y297	4.84	No	No	0	8	9
288	R:R:A298	R:R:F304	8.32	No	Yes	0	7	8
289	R:R:F299	R:R:F304	5.36	No	Yes	0	7	8
290	R:R:E302	R:R:R305	5.82	No	No	0	5	8
291	R:R:E302	R:R:N306	6.57	No	No	0	5	5
292	R:R:K303	R:R:Y307	13.14	No	No	12	6	5
293	R:R:G115	R:R:S75	3.71	No	No	0	9	8
294	R:R:G216	R:R:S215	3.71	No	No	0	4	3
295	R:R:F41	R:R:L80	3.65	No	No	0	7	6
296	L:L:G38	L:L:T30	3.64	No	No	0	0	0
297	R:R:G106	R:R:I164	3.53	No	No	0	5	4
298	R:R:G111	R:R:I110	3.53	No	No	0	8	5
299	R:R:L122	R:R:Y68	3.52	No	Yes	0	9	7
300	R:R:L128	R:R:Y127	3.52	No	No	0	5	8
301	R:R:P250	R:R:T282	3.5	No	Yes	0	9	7
302	R:R:C291	R:R:V40	3.42	No	No	0	8	7
303	R:R:G44	R:R:L80	3.42	No	No	0	8	6
304	L:L:I19	L:L:P20	3.39	No	No	0	0	0
305	R:R:A278	R:R:V254	3.39	No	No	0	6	5
306	R:R:C213	R:R:T123	3.38	No	No	0	8	9
307	R:R:L205	R:R:P206	3.28	No	No	0	6	9
308	R:R:E172	R:R:G173	3.27	Yes	No	0	2	1
309	R:R:A73	R:R:I52	3.25	No	No	0	9	7
310	L:L:C10	R:R:K22	3.23	No	Yes	0	0	3
311	R:R:A159	R:R:K197	3.21	No	No	0	5	3
312	R:R:A249	R:R:L203	3.15	No	No	0	6	8
313	R:R:A233	R:R:L221	3.15	No	No	0	8	8
314	R:R:E18	R:R:P19	3.14	No	Yes	0	3	4
315	R:R:T141	R:R:T143	3.14	No	No	0	6	4
316	R:R:I67	R:R:V142	3.07	No	No	0	7	2
317	R:R:I151	R:R:V147	3.07	No	No	0	3	1
318	L:L:I40	L:L:T30	3.04	Yes	No	0	0	0
319	R:R:A92	R:R:Q93	3.03	No	No	0	4	3
320	L:L:S35	R:R:N267	2.98	No	No	0	0	3
321	R:R:I120	R:R:I124	2.94	No	No	0	7	7
322	R:R:I240	R:R:I296	2.94	No	No	0	8	8
323	R:R:F193	R:R:P162	2.89	No	No	0	3	8
324	L:L:I24	L:L:L65	2.85	No	No	0	0	0
325	R:R:I200	R:R:L196	2.85	No	No	0	5	4
326	R:R:I240	R:R:L236	2.85	No	No	0	8	8
327	R:R:I242	R:R:L246	2.85	No	No	0	5	5
328	R:R:I253	R:R:L257	2.85	No	No	0	6	4
329	R:R:I23	R:R:N24	2.83	No	No	0	3	1
330	R:R:I56	R:R:N57	2.83	No	Yes	0	3	4
331	R:R:D276	R:R:K22	2.77	No	Yes	0	4	3
332	R:R:A136	R:R:R140	2.77	No	Yes	0	5	6
333	R:R:L203	R:R:L207	2.77	No	No	0	8	6
334	L:L:R17	L:L:S16	2.64	No	No	0	0	0
335	R:R:F109	R:R:S160	2.64	No	No	13	5	7
336	R:R:F113	R:R:S160	2.64	Yes	No	13	7	7
337	R:R:F117	R:R:V155	2.62	No	No	0	5	4
338	R:R:F144	R:R:T141	2.59	No	No	0	3	6
339	R:R:R223	R:R:T220	2.59	No	No	0	5	5
340	R:R:F260	R:R:L256	2.44	No	No	0	5	5
341	R:R:D95	R:R:F96	2.39	No	Yes	0	3	7
342	L:L:I19	L:L:W57	2.35	No	Yes	0	0	0
343	R:R:C291	R:R:G44	1.96	No	No	0	8	8
344	R:R:A91	R:R:P34	1.87	No	No	0	4	6
345	R:R:G47	R:R:V46	1.84	No	No	0	8	3
346	R:R:G301	R:R:V300	1.84	No	No	0	8	7
347	R:R:G106	R:R:T105	1.82	No	No	0	5	5
348	L:L:P7	L:L:T6	1.75	Yes	No	0	0	0
349	R:R:G97	R:R:M100	1.75	No	No	0	8	6
350	R:R:G173	R:R:K171	1.74	No	No	0	1	2
351	R:R:G216	R:R:K219	1.74	No	No	0	4	3
352	L:L:C15	L:L:V49	1.71	No	No	0	0	0
353	R:R:G47	R:R:L50	1.71	No	No	0	8	6
354	R:R:A156	R:R:S114	1.71	No	No	0	7	7
355	R:R:L33	R:R:P34	1.64	No	No	0	6	6
356	L:L:S63	L:L:V62	1.62	No	No	0	0	0
357	R:R:C224	R:R:K229	1.62	No	No	0	4	6
358	L:L:A25	L:L:K44	1.61	No	No	0	0	0
359	R:R:V142	R:R:V146	1.6	No	No	0	2	4
360	R:R:V146	R:R:V150	1.6	No	No	0	4	4
361	R:R:V150	R:R:V154	1.6	No	Yes	0	4	4
362	R:R:V154	R:R:V155	1.6	Yes	No	0	4	4
363	R:R:V154	R:R:V157	1.6	Yes	No	0	4	4
364	L:L:T43	L:L:V49	1.59	No	No	0	0	0
365	R:R:T239	R:R:V243	1.59	No	No	0	5	6
366	R:R:T282	R:R:V281	1.59	Yes	No	0	7	5
367	R:R:C58	R:R:N57	1.57	No	Yes	0	5	4
368	R:R:I151	R:R:V155	1.54	No	No	0	3	4
369	R:R:M241	R:R:V211	1.52	No	No	0	8	4
370	R:R:L208	R:R:V204	1.49	No	No	0	4	4
371	R:R:L221	R:R:V234	1.49	No	No	0	8	6
372	R:R:N268	R:R:S271	1.49	No	No	0	4	1
373	R:R:L309	R:R:V310	1.49	No	No	0	4	4
374	R:R:L196	R:R:T195	1.47	No	No	0	4	5
375	R:R:Q277	R:R:V25	1.43	No	No	0	1	1
376	R:R:I212	R:R:L208	1.43	No	No	0	4	4
377	L:L:F12	R:R:C269	1.4	Yes	No	0	0	6
378	R:R:A129	R:R:R140	1.38	No	Yes	0	8	6
379	R:R:L53	R:R:N57	1.37	No	Yes	0	4	4
380	R:R:L309	R:R:N306	1.37	No	No	0	4	5
381	R:R:L309	R:R:Q313	1.33	No	No	0	4	3
382	R:R:R232	R:R:V300	1.31	No	No	0	7	7
383	L:L:R45	L:L:T43	1.29	No	No	0	0	0
384	R:R:E262	R:R:Q188	1.27	No	No	0	3	2
385	R:R:E262	R:R:Q261	1.27	No	Yes	0	3	4
386	R:R:K62	R:R:R60	1.24	No	No	0	7	5
387	R:R:F45	R:R:L81	1.22	Yes	No	0	6	5
388	R:R:F78	R:R:L81	1.22	Yes	No	0	7	5
389	R:R:F247	R:R:L246	1.22	Yes	No	0	8	5
390	R:R:R232	R:R:R305	1.07	No	No	0	7	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:D5	6.5175	4	3	0
2	L:L:P7	3.9	4	0	0
3	L:L:F12	3.9225	4	0	0
4	L:L:F28	8.0925	4	1	0
5	L:L:Q33	7.795	4	3	0
6	L:L:I40	5.315	4	1	0
7	L:L:Q48	7.225	4	1	0
8	L:L:E55	10.5375	4	4	0
9	L:L:W57	11.2083	6	4	0
10	L:L:Y61	5.828	5	4	0
11	R:R:P19	4.63429	7	1	4
12	R:R:K22	4.385	4	9	3
13	R:R:Y37	10.2625	4	0	8
14	R:R:F45	4.995	4	0	6
15	R:R:N48	6.8625	4	0	9
16	R:R:L55	4.825	4	11	7
17	R:R:N57	3.255	4	0	4
18	R:R:Y68	8.07	6	2	7
19	R:R:F78	4.695	4	0	7
20	R:R:T82	5.9775	4	7	7
21	R:R:W86	7.33167	6	7	7
22	R:R:W94	9.538	5	0	9
23	R:R:F96	8.77	4	0	7
24	R:R:Y108	10.52	4	7	7
25	R:R:F112	8.1875	4	0	7
26	R:R:F113	8.5	4	13	7
27	R:R:F118	8.822	5	2	7
28	R:R:D125	8.815	4	2	8
29	R:R:R140	6.255	6	2	6
30	R:R:W153	6.928	5	2	9
31	R:R:V154	2.8375	4	0	4
32	R:R:F166	8.6325	4	6	5
33	R:R:E172	11.5675	4	1	2
34	R:R:F182	6.8425	4	6	5
35	R:R:W190	9.408	5	6	3
36	R:R:Y214	7.48	5	0	9
37	R:R:Y244	9.5125	4	5	9
38	R:R:F247	6.798	5	5	8
39	R:R:W248	10.7275	4	5	9
40	R:R:Y251	11.5	4	0	7
41	R:R:L255	7.63	4	0	6
42	R:R:Q261	4.4775	4	0	4
43	R:R:M279	4.936	5	3	5
44	R:R:T282	5.045	4	0	7
45	R:R:N293	9.735	4	10	9
46	R:R:F304	7.8825	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:D5	L:L:Q33	63.7716	10.44	Yes	Yes	3	0	0
2	L:L:Q33	R:R:M279	36.6437	5.44	Yes	Yes	3	0	5
3	R:R:L255	R:R:M279	63.9127	4.24	Yes	Yes	0	6	5
4	R:R:L255	R:R:Y251	44.2079	17.58	Yes	Yes	0	6	7
5	L:L:L2	R:R:W86	92.2221	4.56	No	Yes	0	0	7
6	R:R:W86	R:R:Y108	24.0232	5.79	Yes	Yes	7	7	7
7	R:R:E283	R:R:Y108	44.7805	8.98	No	Yes	0	6	7
8	R:R:E283	R:R:Y251	45.2079	14.59	No	Yes	0	6	7
9	L:L:L2	R:R:T105	21.4024	10.32	No	No	0	0	5
10	L:L:D5	L:L:S31	31.91	4.42	Yes	No	3	0	0
11	L:L:P7	L:L:Q33	72.1423	4.74	Yes	Yes	0	0	0
12	L:L:P7	L:L:S31	31.7165	5.34	Yes	No	0	0	0
13	L:L:C10	L:L:P7	93.4922	3.77	No	Yes	0	0	0
14	L:L:F28	L:L:I40	37.7888	6.28	Yes	Yes	1	0	0
15	L:L:I40	L:L:T30	61.6628	3.04	Yes	No	0	0	0
16	L:L:C34	L:L:T30	71.2834	5.07	No	No	0	0	0
17	L:L:C10	L:L:C34	73.1785	7.28	No	No	0	0	0
18	L:L:F28	R:R:E172	12.8906	11.66	Yes	Yes	1	0	2
19	L:L:I40	R:R:P19	17.0719	5.08	Yes	Yes	1	0	4
20	L:L:F12	L:L:S35	51.8165	6.61	Yes	No	0	0	0
21	L:L:S35	R:R:Q261	54.5744	8.66	No	Yes	0	0	4
22	R:R:L275	R:R:Q261	59.8968	3.99	No	Yes	0	5	4
23	R:R:L275	R:R:N258	65.2796	6.87	No	No	0	5	4
24	R:R:M279	R:R:N258	28.3658	5.61	Yes	No	3	5	4
25	L:L:F12	L:L:K36	46.1957	3.72	Yes	No	0	0	0
26	L:L:K36	L:L:Y14	44.7643	10.75	No	No	0	0	0
27	L:L:D52	L:L:Y14	43.3329	26.44	No	No	0	0	0
28	L:L:E55	L:L:W57	34.3091	18.54	Yes	Yes	4	0	0
29	L:L:D52	L:L:E55	40.4459	12.99	No	Yes	0	0	0
30	L:L:W57	L:L:Y61	19.2895	5.79	Yes	Yes	4	0	0
31	L:L:I19	L:L:W57	13.0156	2.35	No	Yes	0	0	0
32	L:L:I24	L:L:Y61	13.0116	4.84	No	Yes	0	0	0
33	L:L:F28	R:R:Q170	19.2008	10.54	Yes	No	1	0	1
34	R:R:L255	R:R:T195	30.2407	4.42	Yes	No	0	6	5
35	R:R:T195	R:R:T259	26.8659	12.56	No	No	0	5	5
36	R:R:K191	R:R:T259	14.3422	10.51	No	No	0	4	5
37	R:R:K191	R:R:Y187	13.8341	5.97	No	No	0	4	3
38	R:R:F182	R:R:Y187	12.0277	8.25	Yes	No	0	5	3
39	L:L:S32	R:R:F182	12.2697	6.61	No	Yes	0	0	5
40	R:R:T105	R:R:T167	14.951	6.28	No	No	0	5	5
41	R:R:S180	R:R:T167	13.3785	6.4	No	No	0	4	5
42	L:L:C10	R:R:K22	21.4064	3.23	No	Yes	0	0	3
43	R:R:K22	R:R:V25	15.0397	4.55	Yes	No	9	3	1
44	R:R:Q277	R:R:V25	12.939	1.43	No	No	0	1	1
45	R:R:I28	R:R:Q277	10.802	8.23	No	No	0	2	1
46	R:R:F79	R:R:Y108	33.0793	18.57	No	Yes	0	7	7
47	R:R:F79	R:R:M287	30.1601	7.46	No	No	0	7	8
48	R:R:M287	R:R:Y37	19.4307	8.38	No	Yes	0	8	8
49	R:R:L33	R:R:Y37	11.7536	19.93	No	Yes	0	6	8
50	R:R:M287	R:R:V83	13.6164	6.09	No	No	0	8	7
51	R:R:P84	R:R:V83	12.6164	7.07	No	No	0	9	7
52	R:R:F41	R:R:P84	11.6407	15.89	No	No	0	7	9
53	R:R:F41	R:R:L80	13.2817	3.65	No	No	0	7	6
54	R:R:G44	R:R:L80	10.6407	3.42	No	No	0	8	6
55	R:R:T82	R:R:Y108	27.2207	8.74	Yes	Yes	7	7	7
56	R:R:L107	R:R:T82	100	4.42	No	Yes	0	5	7
57	R:R:F78	R:R:L107	99.2057	8.53	Yes	No	0	7	5
58	R:R:F78	R:R:L81	74.8478	1.22	Yes	No	0	7	5
59	R:R:F45	R:R:L81	73.618	1.22	Yes	No	0	6	5
60	R:R:F112	R:R:I198	90.6254	8.79	Yes	No	0	7	5
61	R:R:F112	R:R:W248	81.6983	5.01	Yes	Yes	0	7	9
62	R:R:H289	R:R:W248	39.7726	15.87	No	Yes	5	9	9
63	R:R:F247	R:R:H289	45.2522	10.18	Yes	No	5	8	9
64	R:R:F247	R:R:I292	39.446	3.77	Yes	No	0	8	6
65	R:R:I292	R:R:I295	38.2726	4.42	No	No	0	6	6
66	R:R:F45	R:R:L77	67.6747	4.87	Yes	No	0	6	7
67	R:R:L77	R:R:N48	66.2675	4.12	No	Yes	0	7	9
68	R:R:D76	R:R:N48	31.7971	12.12	No	Yes	0	9	9
69	R:R:N48	R:R:P294	30.2044	6.52	Yes	No	0	9	9
70	R:R:F299	R:R:I295	35.9139	6.28	No	No	0	7	6
71	R:R:F299	R:R:F304	32.7406	5.36	No	Yes	0	7	8
72	R:R:F304	R:R:V51	15.7615	6.55	Yes	No	0	8	8
73	R:R:L69	R:R:V51	15.1849	4.47	No	No	0	8	8
74	R:R:A298	R:R:F304	15.7615	8.32	No	Yes	0	7	8
75	R:R:A298	R:R:L69	15.1728	4.73	No	No	0	7	8
76	R:R:L55	R:R:L69	28.8537	5.54	Yes	No	0	7	8
77	R:R:F112	R:R:F113	23.6079	13.93	Yes	Yes	0	7	7
78	R:R:F113	R:R:S160	18.1283	2.64	Yes	No	13	7	7
79	R:R:I110	R:R:S160	18.3783	4.64	No	No	0	5	7
80	R:R:I110	R:R:V157	17.2493	7.68	No	No	0	5	4
81	R:R:V154	R:R:V157	16.8421	1.6	Yes	No	0	4	4
82	R:R:V150	R:R:V154	19.2815	1.6	No	Yes	0	4	4
83	R:R:V146	R:R:V150	18.0598	1.6	No	No	0	4	4
84	R:R:V142	R:R:V146	16.8421	1.6	No	No	0	2	4
85	R:R:I67	R:R:V142	15.6768	3.07	No	No	0	7	2
86	R:R:I67	R:R:L61	14.7817	5.71	No	No	0	7	6
87	R:R:D66	R:R:L55	26.8497	4.07	No	Yes	0	8	7
88	R:R:D66	R:R:K59	24.4466	20.74	No	No	0	8	5
89	R:R:K59	R:R:Y307	19.6081	11.94	No	No	12	5	5
90	R:R:C58	R:R:Y307	17.213	8.06	No	No	0	5	5
91	R:R:C58	R:R:N57	14.7776	1.57	No	Yes	0	5	4
92	R:R:F78	R:R:W153	52.2156	4.01	Yes	Yes	0	7	9
93	R:R:F118	R:R:W153	43.8289	9.02	Yes	Yes	2	7	9
94	R:R:F118	R:R:L121	24.0958	4.87	Yes	No	2	7	6
95	R:R:L121	R:R:Y68	30.0633	12.89	No	Yes	2	6	7
96	R:R:D125	R:R:Y68	10.1448	5.75	Yes	Yes	2	8	7
97	R:R:D76	R:R:N293	28.6843	12.12	No	Yes	10	9	9
98	R:R:N293	R:R:P294	28.6884	11.4	Yes	No	0	9	9
99	R:R:W86	R:R:W94	23.1684	7.5	Yes	Yes	0	7	9
100	R:R:F96	R:R:W94	11.7939	20.04	Yes	Yes	0	7	9
101	R:R:V154	R:R:V155	25.3054	1.6	Yes	No	0	4	4
102	R:R:F117	R:R:V155	24.1442	2.62	No	No	0	5	4
103	R:R:F118	R:R:T152	18.6283	12.97	Yes	No	2	7	6
104	R:R:F117	R:R:T152	25.249	3.89	No	No	0	5	6
105	R:R:N293	R:R:Y297	54.3083	5.81	Yes	No	0	9	9
106	R:R:W248	R:R:Y244	40.1556	16.4	Yes	Yes	5	9	9
107	R:R:P206	R:R:Y244	12.1568	6.95	No	Yes	0	9	9
108	R:R:M210	R:R:Y244	34.8817	5.99	No	Yes	0	8	9
109	R:R:M210	R:R:M241	33.543	5.78	No	No	0	8	8
110	R:R:M241	R:R:Y214	30.785	4.79	No	Yes	0	8	9
111	R:R:T123	R:R:Y214	13.6406	6.24	No	Yes	0	9	9
112	R:R:C213	R:R:T123	12.1568	3.38	No	No	0	8	9
113	R:R:C213	R:R:Y127	10.6649	9.41	No	No	0	8	8
114	R:R:F182	R:R:W190	11.6326	5.01	Yes	Yes	6	5	3
115	R:R:F260	R:R:T259	13.0398	10.38	No	No	0	5	5
116	R:R:F260	R:R:L256	12.1568	2.44	No	No	0	5	5
117	R:R:L256	R:R:V199	10.6649	4.47	No	No	0	5	5
118	R:R:I296	R:R:Y297	48.0182	4.84	No	No	0	8	9
119	R:R:I240	R:R:I296	38.5872	2.94	No	No	0	8	8
120	R:R:I240	R:R:L236	35.4744	2.85	No	No	0	8	8
121	R:R:L236	R:R:V300	32.285	7.45	No	No	0	8	7
122	R:R:R232	R:R:V300	25.8901	1.31	No	No	0	7	7
123	R:R:R232	R:R:R305	19.467	1.07	No	No	0	7	8
124	R:R:E302	R:R:R305	16.2453	5.82	No	No	0	5	8
125	R:R:E302	R:R:N306	13.0116	6.57	No	No	0	5	5
126	R:R:I198	R:R:L255	90.9762	4.28	No	Yes	0	5	6
127	L:L:D5	L:L:L2	93.5607	6.79	Yes	No	0	0	0
128	L:L:S32	R:R:S180	12.5237	4.89	No	No	0	0	4
129	L:L:Q33	R:R:N258	38.0993	10.56	Yes	No	3	0	4
130	R:R:T82	R:R:W86	70.4367	4.85	Yes	Yes	7	7	7
131	R:R:F41	R:R:F45	10.7697	6.43	No	Yes	0	7	6
132	R:R:L55	R:R:L61	12.81	4.15	Yes	No	11	7	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S1	R:R:Q194	4.33	0	No	No	0	5	0	1
L:L:S1	R:R:Y251	5.09	0	No	Yes	0	7	0	1
L:L:L2	R:R:W86	4.56	0	No	Yes	0	7	0	1
L:L:L2	R:R:T105	10.32	0	No	No	0	5	0	1
L:L:A3	R:R:W86	6.48	0	No	Yes	0	7	0	1
L:L:A4	R:R:M279	4.83	0	No	Yes	0	5	0	1
L:L:D5	R:R:S179	4.42	3	Yes	No	0	3	0	1
L:L:T6	R:R:K26	7.51	0	No	No	0	1	0	1
L:L:T6	R:R:Q280	7.09	0	No	No	0	3	0	1
L:L:T8	R:R:E172	14.11	1	No	Yes	0	2	0	1
L:L:T8	R:R:H175	4.11	1	No	No	0	1	0	1
L:L:A9	R:R:P19	3.74	1	No	Yes	0	4	0	1
L:L:A9	R:R:Q21	4.55	1	No	No	0	1	0	1
L:L:C11	R:R:P19	3.77	1	No	Yes	0	4	0	1
L:L:F12	R:R:S272	3.96	0	Yes	No	0	3	0	1
L:L:S13	R:R:S17	6.52	0	No	No	0	4	0	1
L:L:D26	R:R:K171	4.15	0	No	No	0	2	0	1
L:L:F28	R:R:Q170	10.54	1	Yes	No	0	1	0	1
L:L:F28	R:R:E172	11.66	1	Yes	Yes	0	2	0	1
L:L:E29	R:R:R168	6.98	1	No	No	0	4	0	1
L:L:E29	R:R:Q170	6.37	1	No	No	0	1	0	1
L:L:E29	R:R:H181	9.85	1	No	No	0	4	0	1
L:L:S31	R:R:S179	6.52	3	No	No	0	3	0	1
L:L:S32	R:R:S180	4.89	0	No	No	0	4	0	1
L:L:S32	R:R:F182	6.61	0	No	Yes	0	5	0	1
L:L:Q33	R:R:N258	10.56	3	Yes	No	0	4	0	1
L:L:Q33	R:R:M279	5.44	3	Yes	Yes	0	5	0	1
L:L:S35	R:R:Q261	8.66	0	No	Yes	0	4	0	1
L:L:P37	R:R:Y187	15.3	0	No	No	0	3	0	1
L:L:I40	R:R:P19	5.08	1	Yes	Yes	0	4	0	1
L:L:R47	R:R:E18	4.65	0	No	No	0	3	0	1
L:L:Q48	R:R:P19	6.32	1	Yes	Yes	0	4	0	1
L:L:Q48	R:R:Q21	6.4	1	Yes	No	0	1	0	1
L:L:C50	R:R:P19	5.65	1	No	Yes	0	4	0	1
L:L:P53	R:R:Y184	9.74	0	No	No	0	1	0	1
L:L:Q59	R:R:Y184	12.4	0	No	No	0	1	0	1
R:R:P19	R:R:Q21	4.74	1	Yes	No	4	1	1	1
R:R:C20	R:R:C269	7.28	0	No	No	9	6	2	1
R:R:K22	R:R:V25	4.55	9	Yes	No	3	1	1	2
R:R:K22	R:R:N273	6.99	9	Yes	No	3	1	1	2
R:R:N273	R:R:V25	5.91	9	No	No	1	1	2	2
R:R:A29	R:R:Q280	4.55	0	No	No	5	3	2	1
R:R:T82	R:R:W86	4.85	7	Yes	Yes	7	7	2	1
R:R:L104	R:R:T82	5.9	7	No	Yes	5	7	2	2
R:R:T82	R:R:Y108	8.74	7	Yes	Yes	7	7	2	2
R:R:W86	R:R:W94	7.5	7	Yes	Yes	7	9	1	2
R:R:L104	R:R:W86	14.81	7	No	Yes	5	7	2	1
R:R:W86	R:R:Y108	5.79	7	Yes	Yes	7	7	1	2
R:R:N98	R:R:R168	4.82	0	No	No	3	4	2	1
R:R:T105	R:R:T167	6.28	0	No	No	5	5	1	2
R:R:E283	R:R:Y108	8.98	0	No	Yes	6	7	2	2
R:R:F166	R:R:F182	7.5	6	Yes	Yes	5	5	2	1
R:R:F166	R:R:W190	16.04	6	Yes	Yes	5	3	2	2
R:R:S180	R:R:T167	6.4	0	No	No	4	5	1	2
R:R:H181	R:R:R168	16.93	1	No	No	4	4	1	1
R:R:H181	R:R:Q170	16.07	1	No	No	4	1	1	1
R:R:K171	R:R:Y176	10.75	0	No	No	2	4	1	2
R:R:E172	R:R:H175	17.23	1	Yes	No	2	1	1	1
R:R:F182	R:R:Y187	8.25	6	Yes	No	5	3	1	1
R:R:F182	R:R:W190	5.01	6	Yes	Yes	5	3	1	2
R:R:K191	R:R:Y187	5.97	0	No	No	4	3	2	1
R:R:I198	R:R:Q194	4.12	0	No	No	5	5	2	1
R:R:I198	R:R:L255	4.28	0	No	Yes	5	6	2	2
R:R:L255	R:R:Y251	17.58	0	Yes	Yes	6	7	2	1
R:R:T282	R:R:Y251	8.74	0	Yes	Yes	7	7	2	1
R:R:E283	R:R:Y251	14.59	0	No	Yes	6	7	2	1
R:R:M279	R:R:V254	4.56	3	Yes	No	5	5	1	2
R:R:T282	R:R:V254	6.35	0	Yes	No	7	5	2	2
R:R:L255	R:R:M279	4.24	0	Yes	Yes	6	5	2	1
R:R:L275	R:R:N258	6.87	0	No	No	5	4	2	1
R:R:M279	R:R:N258	5.61	3	Yes	No	5	4	1	1
R:R:L266	R:R:Q261	3.99	0	No	Yes	4	4	2	1
R:R:L275	R:R:Q261	3.99	0	No	Yes	5	4	2	1
R:R:E172	R:R:G173	3.27	1	Yes	No	2	1	1	2
L:L:C10	R:R:K22	3.23	0	No	Yes	0	3	0	1
R:R:E18	R:R:P19	3.14	0	No	Yes	3	4	1	1
L:L:S35	R:R:N267	2.98	0	No	No	0	3	0	1
R:R:D276	R:R:K22	2.77	0	No	Yes	4	3	2	1
R:R:G106	R:R:T105	1.82	0	No	No	5	5	2	1
R:R:G173	R:R:K171	1.74	0	No	No	1	2	2	1
L:L:F12	R:R:C269	1.4	0	Yes	No	0	6	0	1
R:R:E262	R:R:Q261	1.27	0	No	Yes	3	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7F1Q_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.72
Number of Linked Nodes	349
Number of Links	390
Number of Hubs	46
Number of Links mediated by Hubs	175
Number of Communities	14
Number of Nodes involved in Communities	76
Number of Links involved in Communities	95

Path Summary
Number Of Nodes in MetaPath	133
Number Of Links MetaPath	132
Number of Shortest Paths	81137
Length Of Smallest Path	3
Average Path Length	16.7311
Length of Longest Path	40
Minimum Path Strength	1.22
Average Path Strength	6.79055
Maximum Path Strength	20.77
Minimum Path Correlation	0.7
Average Path Correlation	0.937308
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	52.0057
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.6807
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • virus receptor activity • exogenous protein binding • molecular transducer activity • coreceptor activity • signaling receptor activity • phosphoric ester hydrolase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • phospholipase C activity • hydrolase activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • catalytic activity • phospholipase activity • lipase activity • G protein-coupled chemoattractant receptor activity • C-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • cytokine receptor activity • immune receptor activity • cytoskeletal protein binding • actin binding • C-C chemokine binding • chemokine binding • cytokine binding • chemokine (C-C motif) ligand 5 binding • identical protein binding • CCR5 chemokine receptor binding • CCR chemokine receptor binding • signaling receptor binding • cytokine receptor binding • G protein-coupled receptor binding • chemokine receptor binding • kinase activity • transferase activity • transferase activity, transferring phosphorus-containing groups • catalytic activity, acting on a protein • protein kinase activity • phosphotransferase activity, alcohol group as acceptor • molecular function activator activity • signaling receptor activator activity • chemokine activity • molecular function regulator activity • cytokine activity • signaling receptor regulator activity • receptor ligand activity • CCR1 chemokine receptor binding • chemoattractant activity • enzyme regulator activity • enzyme activator activity • phospholipase activator activity • lipase activator activity • regulation of cellular process • leukocyte apoptotic process • negative regulation of biological process • regulation of programmed cell death • macrophage apoptotic process • negative regulation of leukocyte apoptotic process • negative regulation of cellular process • myeloid cell apoptotic process • regulation of leukocyte apoptotic process • regulation of biological process • negative regulation of programmed cell death • regulation of apoptotic process • biological regulation • negative regulation of macrophage apoptotic process
Gene Ontology	Biological Process	• regulation of cellular process • leukocyte apoptotic process • negative regulation of biological process • regulation of programmed cell death • macrophage apoptotic process • negative regulation of leukocyte apoptotic process • negative regulation of cellular process • myeloid cell apoptotic process • regulation of leukocyte apoptotic process • regulation of biological process • negative regulation of programmed cell death • regulation of apoptotic process • biological regulation • negative regulation of macrophage apoptotic process • cell death • negative regulation of apoptotic process • regulation of macrophage apoptotic process • inflammatory cell apoptotic process • cellular process • negative regulation of myeloid cell apoptotic process • apoptotic process • regulation of myeloid cell apoptotic process • programmed cell death • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • response to stimulus • immune response • immune system process • response to sterol • response to lipid • response to alcohol • response to chemical • response to oxygen-containing compound • response to cholesterol • signaling • cell-cell signaling • cell communication • cellular response to stimulus • biological process involved in interspecies interaction between organisms • response to other organism • cellular response to lipopolysaccharide • response to external stimulus • cellular response to molecule of bacterial origin • response to lipopolysaccharide • cellular response to oxygen-containing compound • response to biotic stimulus • cellular response to biotic stimulus • cellular response to chemical stimulus • response to bacterium • cellular response to lipid • response to external biotic stimulus • response to molecule of bacterial origin • intracellular signal transduction • calcium-mediated signaling • intracellular signaling cassette • signal transduction • MAPK cascade • chemotaxis • taxis • locomotion • cell chemotaxis • dendritic cell chemotaxis • leukocyte migration • dendritic cell migration • mononuclear cell migration • cell migration • cell motility • leukocyte chemotaxis • cell surface receptor signaling pathway • defense response • response to stress • cellular defense response • localization • transport • monoatomic ion transport • monoatomic cation transport • establishment of localization • calcium ion transport • metal ion transport • inflammatory response • G protein-coupled receptor signaling pathway • regulation of localization • cellular localization • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • monoatomic ion transmembrane transport • sarcoplasmic reticulum calcium ion transport • calcium ion homeostasis • release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • negative regulation of sequestering of calcium ion • maintenance of location in cell • monoatomic cation transmembrane transport • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • regulation of sequestering of calcium ion • intracellular monoatomic ion homeostasis • release of sequestered calcium ion into cytosol by endoplasmic reticulum • calcium ion transmembrane import into cytosol • sequestering of calcium ion • inorganic ion transmembrane transport • inorganic cation transmembrane transport • maintenance of location • transmembrane transport • release of sequestered calcium ion into cytosol • cellular homeostasis • chemical homeostasis • calcium ion transmembrane transport • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • regulation of calcium-mediated signaling • positive regulation of calcium-mediated signaling • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of response to stimulus • regulation of cell communication • positive regulation of signaling • developmental process • multicellular organismal process • cellular developmental process • glial cell migration • nervous system development • neurogenesis • multicellular organism development • gliogenesis • cell differentiation • anatomical structure development • astrocyte cell migration • system development • cell activation • regulation of defense response • regulation of response to external stimulus • regulation of inflammatory response • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stress • positive regulation of defense response • positive regulation of locomotion • regulation of cell motility • regulation of microglial cell migration • macrophage migration • regulation of glial cell migration • positive regulation of cell migration • regulation of macrophage migration • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • positive regulation of microglial cell migration • regulation of immune system process • regulation of mononuclear cell migration • positive regulation of immune system process • positive regulation of macrophage migration • regulation of leukocyte migration • microglial cell migration • positive regulation of leukocyte migration • positive regulation of glial cell migration • regulation of locomotion • positive regulation of chemotaxis • regulation of lymphocyte chemotaxis • natural killer cell chemotaxis • positive regulation of natural killer cell chemotaxis • regulation of leukocyte chemotaxis • positive regulation of lymphocyte migration • lymphocyte migration • positive regulation of leukocyte chemotaxis • regulation of natural killer cell chemotaxis • lymphocyte chemotaxis • regulation of lymphocyte migration • positive regulation of lymphocyte chemotaxis • regulation of chemotaxis • regulation of biosynthetic process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of metabolic process • biosynthetic process • positive regulation of gene expression • positive regulation of biosynthetic process • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • regulation of metabolic process • neutrophil chemotaxis • neutrophil migration • granulocyte migration • granulocyte chemotaxis • neuron apoptotic process • positive regulation of programmed cell death • positive regulation of apoptotic process • positive regulation of neuron apoptotic process • regulation of neuron apoptotic process • myeloid leukocyte differentiation • regulation of leukocyte differentiation • regulation of developmental process • cell development • regulation of cell differentiation • regulation of cell development • regulation of osteoclast differentiation • osteoclast differentiation • regulation of multicellular organismal process • negative regulation of cell differentiation • negative regulation of hemopoiesis • regulation of multicellular organismal development • negative regulation of leukocyte differentiation • hemopoiesis • regulation of myeloid cell differentiation • negative regulation of developmental process • regulation of myeloid leukocyte differentiation • negative regulation of myeloid cell differentiation • negative regulation of osteoclast differentiation • negative regulation of myeloid leukocyte differentiation • negative regulation of cell development • myeloid cell differentiation • negative regulation of immune system process • regulation of hemopoiesis • negative regulation of multicellular organismal process • leukocyte differentiation • response to toxic substance • regulation of behavior • behavior • interleukin-1 production • regulation of interleukin-1 beta production • positive regulation of interleukin-1 beta production • regulation of cytokine production • cytokine production • positive regulation of interleukin-1 production • regulation of interleukin-1 production • interleukin-1 beta production • positive regulation of multicellular organismal process • positive regulation of cytokine production • cellular component organization • organelle organization • cellular component organization or biogenesis • cytoskeleton organization • regulation of macrophage activation • positive regulation of macrophage activation • regulation of leukocyte activation • positive regulation of microglial cell activation • regulation of cell activation • positive regulation of neuroinflammatory response • myeloid leukocyte activation • leukocyte activation • macrophage activation • positive regulation of cell activation • leukocyte activation involved in inflammatory response • regulation of neuroinflammatory response • positive regulation of leukocyte activation • microglial cell activation • glial cell activation • regulation of microglial cell activation • neuroinflammatory response • regulated exocytosis • eosinophil activation • cell activation involved in immune response • leukocyte degranulation • myeloid leukocyte mediated immunity • vesicle-mediated transport • secretion by cell • establishment of localization in cell • leukocyte activation involved in immune response • eosinophil degranulation • leukocyte mediated immunity • eosinophil activation involved in immune response • secretion • export from cell • myeloid cell activation involved in immune response • immune effector process • exocytosis • eosinophil mediated immunity • granulocyte activation • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of transport • regulation of monoatomic ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • calcium ion import • regulation of metal ion transport • eosinophil chemotaxis • eosinophil migration • response to peptide • cellular response to interleukin-1 • response to cytokine • cellular response to cytokine stimulus • response to interleukin-1 • ossification • osteoblast differentiation • viral gene expression • negative regulation by host of viral transcription • viral process • modulation of process of another organism • viral transcription • host-mediated perturbation of symbiont process • positive regulation of ERK1 and ERK2 cascade • positive regulation of MAPK cascade • regulation of MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • system process • nervous system process • regulation of system process • sensory perception of pain • regulation of nervous system process • sensory perception • regulation of sensory perception • regulation of sensory perception of pain • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • regulation of cell shape • cell morphogenesis • regulation of cell morphogenesis • anatomical structure morphogenesis • regulation of anatomical structure morphogenesis • cellular response to tumor necrosis factor • response to tumor necrosis factor • response to type II interferon • defense response to symbiont • cellular response to type II interferon • defense response to other organism • innate immune response • monocyte chemotaxis • humoral immune response • antimicrobial humoral response • antimicrobial humoral immune response mediated by antimicrobial peptide • macrophage chemotaxis • negative regulation of metabolic process • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of macromolecule metabolic process • regulation of tumor necrosis factor production • positive regulation of tumor necrosis factor superfamily cytokine production • tumor necrosis factor superfamily cytokine production • positive regulation of tumor necrosis factor production • tumor necrosis factor production • regulation of tumor necrosis factor superfamily cytokine production • T cell chemotaxis • T cell migration • negative regulation of biomineral tissue development • regulation of biomineral tissue development • regulation of bone mineralization • negative regulation of bone mineralization • biomineral tissue development • bone mineralization • animal organ development • tissue development • negative regulation of ossification • regulation of ossification • cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • intracellular anatomical structure • cytoplasm • membrane-bounded organelle • endosome • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system
Gene Ontology	Cellular Component	• cell periphery • cellular anatomical structure • cell surface • membrane • plasma membrane • external side of plasma membrane • side of membrane • intracellular anatomical structure • cytoplasm • membrane-bounded organelle • endosome • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cytoplasmic vesicle • organelle • vesicle • cytosol • extracellular region • extracellular space • D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• G protein-coupled receptor-like • Interleukin 8-like chemokines • Ras-like P-loop GTPases
SCOP2	Family Identifier	• G protein-coupled receptor-like • Interleukin 8-like chemokines • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P51681
Sequence	>7F1Q_nogp_Chain_R S E P C Q K I N V K Q I A A R L L P P L Y S L V F I F G F V G N M L V I L I L I N C K R L K S M T D I Y L L N L A I S D L F F L L T V P F W A H Y A A A Q W D F G N T M C Q L L T G L Y F I G F F S G I F F I I L L T I D R Y L A V V H A V F A L K A R T V T F G V V T S V I T W V V A V F A S L P N I I F T R S Q K E G L H Y T C S S H F P Y S Q Y Q F W K N F Q T L K I V I L G L V L P L L V M V I C Y S G I L K T L L R C R N E K K R H R A V R L I F T I M I V Y F L F W A P Y N I V L L L N T F Q E F F G L N N C S S S N R L D Q A M Q V T E T L G M T H C C I N P I I Y A F V G E K F R N Y L L V F F Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7F1T	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	-	2.6	2021-07-14	10.1038/s41467-021-24438-5
	7F1S	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	2.8	2021-07-14	10.1038/s41467-021-24438-5
	7F1S (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		2.8	2021-07-14	10.1038/s41467-021-24438-5
	7F1R	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	3	2021-07-14	10.1038/s41467-021-24438-5
	7F1R (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		3	2021-07-14	10.1038/s41467-021-24438-5
	7F1Q	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	Gi1/β1/γ2	2.9	2021-07-14	10.1038/s41467-021-24438-5
	7F1Q (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-		2.9	2021-07-14	10.1038/s41467-021-24438-5
	7O7F	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-	Gi1/β1/γ1	3.15	2021-06-30	10.1126/sciadv.abg8685
	7O7F (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-		3.15	2021-06-30	10.1126/sciadv.abg8685
	6MET	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	4.5	2018-12-12	10.1038/s41586-018-0804-9
	6MEO	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	3.9	2018-12-12	10.1038/s41586-018-0804-9
	6AKY	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
	6AKX	A	Protein	Chemokine	CCR5	Homo sapiens	-	A4R	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
	5UIW	A	Protein	Chemokine	CCR5	Homo sapiens	5P7-CCL5	-	-	2.2	2017-06-28	10.1016/j.immuni.2017.05.002
	4MBS	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.71	2013-09-11	10.1126/science.1241475

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