psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:S24	R:R:Q194	4.33	No	No	0	5	5
2	L:L:S24	R:R:Y251	5.09	No	Yes	0	5	7
3	L:L:D28	L:L:L25	6.79	Yes	No	0	4	1
4	L:L:L25	R:R:W86	4.56	No	Yes	0	1	7
5	L:L:L25	R:R:T105	10.32	No	No	0	1	5
6	L:L:A26	R:R:W86	6.48	No	Yes	0	4	7
7	L:L:A27	R:R:M279	4.83	No	Yes	0	4	5
8	L:L:D28	L:L:S54	4.42	Yes	No	3	4	8
9	L:L:D28	L:L:Q56	10.44	Yes	Yes	3	4	4
10	L:L:D28	R:R:S179	4.42	Yes	No	3	4	3
11	L:L:T29	R:R:K26	7.51	No	No	0	3	1
12	L:L:T29	R:R:Q280	7.09	No	No	0	3	3
13	L:L:C33	L:L:P30	3.77	No	Yes	0	9	6
14	L:L:P30	L:L:S54	5.34	Yes	No	0	6	8
15	L:L:P30	L:L:Q56	4.74	Yes	Yes	0	6	4
16	L:L:F51	L:L:T31	3.89	Yes	No	1	4	4
17	L:L:T31	R:R:E172	14.11	No	Yes	1	4	2
18	L:L:T31	R:R:H175	4.11	No	No	1	4	1
19	L:L:A32	R:R:P19	3.74	No	Yes	1	4	4
20	L:L:A32	R:R:Q21	4.55	No	No	1	4	1
21	L:L:C33	L:L:C57	7.28	No	No	0	9	9
22	L:L:C34	L:L:C73	7.28	No	No	1	9	9
23	L:L:C34	R:R:P19	3.77	No	Yes	1	9	4
24	L:L:F35	L:L:S58	6.61	Yes	No	0	5	5
25	L:L:F35	L:L:K59	3.72	Yes	No	0	5	3
26	L:L:F35	R:R:S272	3.96	Yes	No	0	5	3
27	L:L:S36	R:R:S17	6.52	No	No	0	4	4
28	L:L:K59	L:L:Y37	10.75	No	No	0	3	6
29	L:L:D75	L:L:Y37	26.44	No	No	0	7	6
30	L:L:Q41	L:L:W80	23	No	Yes	4	3	8
31	L:L:Q41	L:L:Y84	5.64	No	Yes	4	3	4
32	L:L:I42	L:L:V72	4.61	No	No	0	6	6
33	L:L:N45	L:L:P43	6.52	No	No	8	3	7
34	L:L:F46	L:L:P43	7.22	No	No	8	3	7
35	L:L:Q44	L:L:Y84	4.51	No	Yes	0	3	4
36	L:L:F46	L:L:N45	8.46	No	No	8	3	3
37	L:L:F64	L:L:I47	8.79	No	No	0	8	7
38	L:L:I47	L:L:Y84	4.84	No	Yes	0	7	4
39	L:L:D49	R:R:K171	4.15	No	No	0	5	2
40	L:L:V85	L:L:Y50	3.79	No	No	0	6	7
41	L:L:L88	L:L:Y50	7.03	No	No	0	8	7
42	L:L:E89	L:L:Y50	10.1	No	No	0	6	7
43	L:L:F51	L:L:I63	6.28	Yes	Yes	1	4	8
44	L:L:F51	R:R:Q170	10.54	Yes	No	1	4	1
45	L:L:F51	R:R:E172	11.66	Yes	Yes	1	4	2
46	L:L:E52	R:R:R168	6.98	No	No	1	3	4
47	L:L:E52	R:R:Q170	6.37	No	No	1	3	1
48	L:L:E52	R:R:H181	9.85	No	No	1	3	4
49	L:L:C57	L:L:T53	5.07	No	No	0	9	9
50	L:L:S54	R:R:S179	6.52	No	No	3	8	3
51	L:L:S55	R:R:S180	4.89	No	No	0	7	4
52	L:L:S55	R:R:F182	6.61	No	Yes	0	7	5
53	L:L:Q56	R:R:N258	10.56	Yes	No	3	4	4
54	L:L:Q56	R:R:M279	5.44	Yes	Yes	3	4	5
55	L:L:S58	R:R:Q261	8.66	No	Yes	0	5	4
56	L:L:P60	R:R:Y187	15.3	No	No	0	6	3
57	L:L:G61	L:L:P76	4.06	No	No	0	8	9
58	L:L:F64	L:L:V62	6.55	No	No	0	8	8
59	L:L:I63	L:L:Q71	6.86	Yes	Yes	1	8	4
60	L:L:I63	R:R:P19	5.08	Yes	Yes	1	8	4
61	L:L:L65	L:L:Q71	9.32	No	Yes	0	5	4
62	L:L:R70	L:L:S69	10.54	No	No	0	5	5
63	L:L:R70	R:R:E18	4.65	No	No	0	5	3
64	L:L:Q71	R:R:P19	6.32	Yes	Yes	1	4	4
65	L:L:Q71	R:R:Q21	6.4	Yes	No	1	4	1
66	L:L:C73	R:R:P19	5.65	No	Yes	1	9	4
67	L:L:A74	L:L:V81	5.09	No	No	0	8	9
68	L:L:D75	L:L:S77	5.89	No	No	0	7	3
69	L:L:D75	L:L:E78	12.99	No	Yes	0	7	4
70	L:L:P76	R:R:Y184	9.74	No	No	0	9	1
71	L:L:E78	L:L:E79	6.34	Yes	No	4	4	1
72	L:L:E78	L:L:W80	18.54	Yes	Yes	4	4	8
73	L:L:E78	L:L:V81	4.28	Yes	No	4	4	9
74	L:L:E79	L:L:W80	6.54	No	Yes	4	1	8
75	L:L:V81	L:L:W80	11.03	No	Yes	4	9	8
76	L:L:W80	L:L:Y84	5.79	Yes	Yes	4	8	4
77	L:L:Q82	R:R:Y184	12.4	No	No	0	7	1
78	L:L:K83	L:L:Y84	8.36	No	Yes	0	3	4
79	L:L:D87	L:L:K83	11.06	No	No	0	2	3
80	R:R:P19	R:R:Q21	4.74	Yes	No	1	4	1
81	R:R:C20	R:R:C269	7.28	No	No	0	9	6
82	R:R:K22	R:R:V25	4.55	Yes	No	9	3	1
83	R:R:K22	R:R:N273	6.99	Yes	No	9	3	1
84	R:R:N24	R:R:Q27	3.96	No	No	0	1	2
85	R:R:N273	R:R:V25	5.91	No	No	9	1	1
86	R:R:I28	R:R:Q27	6.86	No	No	0	2	2
87	R:R:I28	R:R:R31	3.76	No	No	0	2	3
88	R:R:I28	R:R:Q277	8.23	No	No	0	2	1
89	R:R:A29	R:R:Q280	4.55	No	No	0	5	3
90	R:R:L32	R:R:P35	4.93	No	No	0	6	5
91	R:R:L33	R:R:Y37	19.93	No	Yes	0	6	8
92	R:R:A90	R:R:L33	4.73	No	No	0	5	6
93	R:R:P34	R:R:P35	5.84	No	No	0	6	5
94	R:R:L36	R:R:T284	4.42	No	No	0	6	6
95	R:R:A87	R:R:Y37	4	No	Yes	0	6	8
96	R:R:T284	R:R:Y37	8.74	No	Yes	0	6	8
97	R:R:M287	R:R:Y37	8.38	No	Yes	0	8	8
98	R:R:L39	R:R:V40	4.47	No	No	0	5	7
99	R:R:F41	R:R:F45	6.43	No	Yes	0	7	6
100	R:R:F41	R:R:P84	15.89	No	No	0	7	9
101	R:R:F43	R:R:I295	5.02	No	No	0	5	6
102	R:R:F45	R:R:M49	7.46	Yes	No	0	6	3
103	R:R:F45	R:R:L77	4.87	Yes	No	0	6	7
104	R:R:A73	R:R:N48	4.69	No	Yes	0	9	9
105	R:R:D76	R:R:N48	12.12	No	Yes	0	9	9
106	R:R:L77	R:R:N48	4.12	No	Yes	0	7	9
107	R:R:N48	R:R:P294	6.52	Yes	No	0	9	9
108	R:R:F299	R:R:L50	4.87	No	No	0	7	6
109	R:R:L69	R:R:V51	4.47	No	No	0	8	8
110	R:R:F304	R:R:V51	6.55	Yes	No	0	8	8
111	R:R:F304	R:R:I54	11.3	Yes	No	0	8	7
112	R:R:I54	R:R:L308	5.71	No	No	0	7	6
113	R:R:L55	R:R:L61	4.15	Yes	No	11	7	6
114	R:R:D66	R:R:L55	4.07	No	Yes	0	8	7
115	R:R:L55	R:R:L69	5.54	Yes	No	0	7	8
116	R:R:L55	R:R:L70	5.54	Yes	No	11	7	6
117	R:R:I56	R:R:R60	5.01	No	No	0	3	5
118	R:R:F311	R:R:N57	7.25	No	Yes	0	4	4
119	R:R:C58	R:R:Y307	8.06	No	No	0	5	5
120	R:R:D66	R:R:K59	20.74	No	No	0	8	5
121	R:R:K303	R:R:K59	7.18	No	No	12	6	5
122	R:R:K59	R:R:Y307	11.94	No	No	12	5	5
123	R:R:I67	R:R:L61	5.71	No	No	0	7	6
124	R:R:L61	R:R:L70	5.54	No	No	11	6	6
125	R:R:R140	R:R:S63	5.27	Yes	No	0	6	7
126	R:R:M64	R:R:Y68	13.17	No	Yes	2	6	7
127	R:R:D125	R:R:M64	4.16	Yes	No	2	8	6
128	R:R:M64	R:R:R140	4.96	No	Yes	2	6	6
129	R:R:D125	R:R:T65	8.67	Yes	No	2	8	8
130	R:R:R140	R:R:T65	6.47	Yes	No	2	6	8
131	R:R:L121	R:R:Y68	12.89	No	Yes	2	6	7
132	R:R:D125	R:R:Y68	5.75	Yes	Yes	2	8	7
133	R:R:G145	R:R:Y68	4.35	No	Yes	0	7	7
134	R:R:T148	R:R:Y68	8.74	No	Yes	0	6	7
135	R:R:A298	R:R:L69	4.73	No	No	0	7	8
136	R:R:F118	R:R:N71	13.29	Yes	No	2	7	9
137	R:R:N71	R:R:S149	10.43	No	No	2	9	7
138	R:R:N71	R:R:W153	6.78	No	Yes	2	9	9
139	R:R:D76	R:R:L72	6.79	No	No	10	9	9
140	R:R:L72	R:R:N293	9.61	No	Yes	10	9	9
141	R:R:F78	R:R:I74	5.02	Yes	No	0	7	6
142	R:R:S114	R:R:S75	6.52	No	No	2	7	8
143	R:R:S75	R:R:W153	6.18	No	Yes	2	8	9
144	R:R:D76	R:R:N293	12.12	No	Yes	10	9	9
145	R:R:F78	R:R:L107	8.53	Yes	No	0	7	5
146	R:R:F78	R:R:W153	4.01	Yes	Yes	0	7	9
147	R:R:F79	R:R:Y108	18.57	No	Yes	0	7	7
148	R:R:F79	R:R:M287	7.46	No	No	0	7	8
149	R:R:C290	R:R:F79	4.19	No	No	0	8	7
150	R:R:T82	R:R:W86	4.85	Yes	Yes	7	7	7
151	R:R:L104	R:R:T82	5.9	No	Yes	7	5	7
152	R:R:L107	R:R:T82	4.42	No	Yes	0	5	7
153	R:R:T82	R:R:Y108	8.74	Yes	Yes	7	7	7
154	R:R:P84	R:R:V83	7.07	No	No	0	9	7
155	R:R:M287	R:R:V83	6.09	No	No	0	8	7
156	R:R:F85	R:R:F96	6.43	No	Yes	0	6	7
157	R:R:F85	R:R:L104	8.53	No	No	0	6	5
158	R:R:W86	R:R:W94	7.5	Yes	Yes	0	7	9
159	R:R:L104	R:R:W86	14.81	No	Yes	7	5	7
160	R:R:W86	R:R:Y108	5.79	Yes	Yes	7	7	7
161	R:R:D95	R:R:H88	3.78	No	No	0	3	5
162	R:R:W94	R:R:Y89	8.68	Yes	No	0	9	4
163	R:R:T177	R:R:Y89	7.49	No	No	0	2	4
164	R:R:D95	R:R:Q93	6.53	No	No	0	3	3
165	R:R:F96	R:R:W94	20.04	Yes	Yes	0	7	9
166	R:R:C101	R:R:W94	6.53	No	Yes	0	9	9
167	R:R:S169	R:R:W94	4.94	No	Yes	0	4	9
168	R:R:F96	R:R:M100	6.22	Yes	No	0	7	6
169	R:R:N98	R:R:Q102	9.24	No	No	0	3	7
170	R:R:N98	R:R:R168	4.82	No	No	0	3	4
171	R:R:C101	R:R:C178	7.28	No	No	0	9	9
172	R:R:T105	R:R:T167	6.28	No	No	0	5	5
173	R:R:E283	R:R:Y108	8.98	No	Yes	0	6	7
174	R:R:F109	R:R:F113	7.5	No	Yes	13	5	7
175	R:R:F109	R:R:N163	20.54	No	No	0	5	4
176	R:R:I110	R:R:V157	7.68	No	No	0	5	4
177	R:R:I110	R:R:S160	4.64	No	No	0	5	7
178	R:R:F112	R:R:F113	13.93	Yes	Yes	0	7	7
179	R:R:F112	R:R:I116	5.02	Yes	No	0	7	7
180	R:R:F112	R:R:I198	8.79	Yes	No	0	7	5
181	R:R:F112	R:R:W248	5.01	Yes	Yes	0	7	9
182	R:R:F113	R:R:K197	9.93	Yes	No	0	7	3
183	R:R:S114	R:R:W153	8.65	No	Yes	2	7	9
184	R:R:F117	R:R:T152	3.89	No	No	0	5	6
185	R:R:F117	R:R:L201	7.31	No	No	0	5	4
186	R:R:F118	R:R:L121	4.87	Yes	No	2	7	6
187	R:R:F118	R:R:S149	3.96	Yes	No	2	7	7
188	R:R:F118	R:R:T152	12.97	Yes	No	2	7	6
189	R:R:F118	R:R:W153	9.02	Yes	Yes	2	7	9
190	R:R:I119	R:R:Y297	10.88	No	No	0	8	9
191	R:R:I120	R:R:P206	8.47	No	No	0	7	9
192	R:R:I120	R:R:V209	4.61	No	No	0	7	6
193	R:R:L121	R:R:T152	4.42	No	No	2	6	6
194	R:R:T123	R:R:Y214	6.24	No	Yes	0	9	9
195	R:R:D125	R:R:R140	16.68	Yes	Yes	2	8	6
196	R:R:R126	R:R:Y214	8.23	No	Yes	0	9	9
197	R:R:V131	R:R:Y127	10.09	No	No	0	7	8
198	R:R:C213	R:R:Y127	9.41	No	No	0	8	8
199	R:R:I217	R:R:V130	15.36	No	No	0	8	8
200	R:R:T220	R:R:V130	4.76	No	No	0	5	8
201	R:R:H132	R:R:V131	8.3	No	No	0	6	7
202	R:R:F135	R:R:H132	4.53	No	No	0	5	6
203	R:R:F135	R:R:K138	4.96	No	No	0	5	3
204	R:R:A139	R:R:F135	5.55	No	No	0	4	5
205	R:R:F144	R:R:T148	7.78	No	No	0	3	6
206	R:R:F158	R:R:V154	6.55	No	Yes	0	4	4
207	R:R:I164	R:R:L161	4.28	No	No	0	4	4
208	R:R:F166	R:R:I165	3.77	Yes	No	0	5	3
209	R:R:F166	R:R:F182	7.5	Yes	Yes	6	5	5
210	R:R:F166	R:R:P183	7.22	Yes	No	0	5	3
211	R:R:F166	R:R:W190	16.04	Yes	Yes	6	5	3
212	R:R:S180	R:R:T167	6.4	No	No	0	4	5
213	R:R:H181	R:R:R168	16.93	No	No	1	4	4
214	R:R:C178	R:R:S169	5.16	No	No	0	9	4
215	R:R:H181	R:R:Q170	16.07	No	No	1	4	1
216	R:R:K171	R:R:Y176	10.75	No	No	0	2	4
217	R:R:E172	R:R:H175	17.23	Yes	No	1	2	1
218	R:R:F182	R:R:Y187	8.25	Yes	No	0	5	3
219	R:R:F182	R:R:W190	5.01	Yes	Yes	6	5	3
220	R:R:Q186	R:R:S185	4.33	No	No	0	3	3
221	R:R:F189	R:R:Q186	9.37	No	No	6	1	3
222	R:R:Q186	R:R:W190	10.95	No	Yes	6	3	3
223	R:R:K191	R:R:Y187	5.97	No	No	0	4	3
224	R:R:K191	R:R:Q188	4.07	No	No	0	4	2
225	R:R:N192	R:R:Q188	6.6	No	No	0	3	2
226	R:R:F189	R:R:W190	8.02	No	Yes	6	1	3
227	R:R:F193	R:R:W190	7.02	No	Yes	0	3	3
228	R:R:K191	R:R:T259	10.51	No	No	0	4	5
229	R:R:F260	R:R:N192	8.46	No	No	0	5	3
230	R:R:I198	R:R:Q194	4.12	No	No	0	5	5
231	R:R:L255	R:R:T195	4.42	Yes	No	0	6	5
232	R:R:T195	R:R:T259	12.56	No	No	0	5	5
233	R:R:I198	R:R:L255	4.28	No	Yes	0	5	6
234	R:R:N252	R:R:V199	5.91	No	No	0	8	5
235	R:R:L256	R:R:V199	4.47	No	No	0	5	5
236	R:R:G202	R:R:N252	5.09	No	No	0	6	8
237	R:R:L203	R:R:N252	10.98	No	No	0	8	8
238	R:R:L205	R:R:L208	4.15	No	No	0	6	4
239	R:R:P206	R:R:Y244	6.95	No	Yes	0	9	9
240	R:R:M210	R:R:M241	5.78	No	No	0	8	8
241	R:R:M210	R:R:Y244	5.99	No	Yes	0	8	9
242	R:R:I217	R:R:Y214	4.84	No	Yes	0	8	9
243	R:R:I237	R:R:Y214	13.3	No	Yes	0	8	9
244	R:R:M241	R:R:Y214	4.79	No	Yes	0	8	9
245	R:R:L218	R:R:V234	5.96	No	No	0	4	6
246	R:R:I237	R:R:L218	7.14	No	No	0	8	4
247	R:R:C224	R:R:R230	4.18	No	No	0	4	7
248	R:R:K228	R:R:N226	15.39	No	No	14	5	4
249	R:R:K229	R:R:N226	11.19	No	No	14	6	4
250	R:R:E227	R:R:R230	6.98	No	No	0	3	7
251	R:R:K228	R:R:K229	4.31	No	No	14	5	6
252	R:R:R232	R:R:R235	4.26	No	No	0	7	5
253	R:R:F238	R:R:V234	3.93	No	No	0	5	6
254	R:R:L236	R:R:V300	7.45	No	No	0	8	7
255	R:R:I296	R:R:V243	4.61	No	No	0	8	6
256	R:R:W248	R:R:Y244	16.4	Yes	Yes	5	9	9
257	R:R:H289	R:R:Y244	8.71	No	Yes	5	9	9
258	R:R:A249	R:R:F245	8.32	No	No	0	6	5
259	R:R:F247	R:R:L285	9.74	Yes	No	5	8	8
260	R:R:F247	R:R:T288	9.08	Yes	No	5	8	5
261	R:R:F247	R:R:H289	10.18	Yes	No	5	8	9
262	R:R:F247	R:R:I292	3.77	Yes	No	0	8	6
263	R:R:G286	R:R:W248	5.63	No	Yes	0	8	9
264	R:R:H289	R:R:W248	15.87	No	Yes	5	9	9
265	R:R:L255	R:R:Y251	17.58	Yes	Yes	0	6	7
266	R:R:T282	R:R:Y251	8.74	Yes	Yes	0	7	7
267	R:R:E283	R:R:Y251	14.59	No	Yes	0	6	7
268	R:R:M279	R:R:V254	4.56	Yes	No	0	5	5
269	R:R:T282	R:R:V254	6.35	Yes	No	0	7	5
270	R:R:L255	R:R:M279	4.24	Yes	Yes	0	6	5
271	R:R:F264	R:R:L257	6.09	No	No	0	1	4
272	R:R:L257	R:R:L275	5.54	No	No	0	4	5
273	R:R:L275	R:R:N258	6.87	No	No	0	5	4
274	R:R:M279	R:R:N258	5.61	Yes	No	3	5	4
275	R:R:F260	R:R:T259	10.38	No	No	0	5	5
276	R:R:L266	R:R:Q261	3.99	No	Yes	0	4	4
277	R:R:L275	R:R:Q261	3.99	No	Yes	0	5	4
278	R:R:F263	R:R:F264	6.43	No	No	0	1	1
279	R:R:L266	R:R:S271	9.01	No	No	0	4	1
280	R:R:N268	R:R:S270	4.47	No	No	0	4	1
281	R:R:R274	R:R:S271	3.95	No	No	0	2	1
282	R:R:L285	R:R:T288	4.42	No	No	5	8	5
283	R:R:I292	R:R:I295	4.42	No	No	0	6	6
284	R:R:N293	R:R:P294	11.4	Yes	No	0	9	9
285	R:R:N293	R:R:Y297	5.81	Yes	No	0	9	9
286	R:R:F299	R:R:I295	6.28	No	No	0	7	6
287	R:R:I296	R:R:Y297	4.84	No	No	0	8	9
288	R:R:A298	R:R:F304	8.32	No	Yes	0	7	8
289	R:R:F299	R:R:F304	5.36	No	Yes	0	7	8
290	R:R:E302	R:R:R305	5.82	No	No	0	5	8
291	R:R:E302	R:R:N306	6.57	No	No	0	5	5
292	R:R:K303	R:R:Y307	13.14	No	No	12	6	5
293	R:R:G115	R:R:S75	3.71	No	No	0	9	8
294	R:R:G216	R:R:S215	3.71	No	No	0	4	3
295	R:R:F41	R:R:L80	3.65	No	No	0	7	6
296	L:L:G61	L:L:T53	3.64	No	No	0	8	9
297	R:R:G106	R:R:I164	3.53	No	No	0	5	4
298	R:R:G111	R:R:I110	3.53	No	No	0	8	5
299	R:R:L122	R:R:Y68	3.52	No	Yes	0	9	7
300	R:R:L128	R:R:Y127	3.52	No	No	0	5	8
301	R:R:P250	R:R:T282	3.5	No	Yes	0	9	7
302	R:R:C291	R:R:V40	3.42	No	No	0	8	7
303	R:R:G44	R:R:L80	3.42	No	No	0	8	6
304	L:L:I42	L:L:P43	3.39	No	No	0	6	7
305	R:R:A278	R:R:V254	3.39	No	No	0	6	5
306	R:R:C213	R:R:T123	3.38	No	No	0	8	9
307	R:R:L205	R:R:P206	3.28	No	No	0	6	9
308	R:R:E172	R:R:G173	3.27	Yes	No	0	2	1
309	R:R:A73	R:R:I52	3.25	No	No	0	9	7
310	L:L:C33	R:R:K22	3.23	No	Yes	0	9	3
311	R:R:A159	R:R:K197	3.21	No	No	0	5	3
312	R:R:A249	R:R:L203	3.15	No	No	0	6	8
313	R:R:A233	R:R:L221	3.15	No	No	0	8	8
314	R:R:E18	R:R:P19	3.14	No	Yes	0	3	4
315	R:R:T141	R:R:T143	3.14	No	No	0	6	4
316	R:R:I67	R:R:V142	3.07	No	No	0	7	2
317	R:R:I151	R:R:V147	3.07	No	No	0	3	1
318	L:L:I63	L:L:T53	3.04	Yes	No	0	8	9
319	R:R:A92	R:R:Q93	3.03	No	No	0	4	3
320	L:L:S58	R:R:N267	2.98	No	No	0	5	3
321	R:R:I120	R:R:I124	2.94	No	No	0	7	7
322	R:R:I240	R:R:I296	2.94	No	No	0	8	8
323	R:R:F193	R:R:P162	2.89	No	No	0	3	8
324	L:L:I47	L:L:L88	2.85	No	No	0	7	8
325	R:R:I200	R:R:L196	2.85	No	No	0	5	4
326	R:R:I240	R:R:L236	2.85	No	No	0	8	8
327	R:R:I242	R:R:L246	2.85	No	No	0	5	5
328	R:R:I253	R:R:L257	2.85	No	No	0	6	4
329	R:R:I23	R:R:N24	2.83	No	No	0	3	1
330	R:R:I56	R:R:N57	2.83	No	Yes	0	3	4
331	R:R:D276	R:R:K22	2.77	No	Yes	0	4	3
332	R:R:A136	R:R:R140	2.77	No	Yes	0	5	6
333	R:R:L203	R:R:L207	2.77	No	No	0	8	6
334	L:L:R40	L:L:S39	2.64	No	No	0	4	4
335	R:R:F109	R:R:S160	2.64	No	No	13	5	7
336	R:R:F113	R:R:S160	2.64	Yes	No	13	7	7
337	R:R:F117	R:R:V155	2.62	No	No	0	5	4
338	R:R:F144	R:R:T141	2.59	No	No	0	3	6
339	R:R:R223	R:R:T220	2.59	No	No	0	5	5
340	R:R:F260	R:R:L256	2.44	No	No	0	5	5
341	R:R:D95	R:R:F96	2.39	No	Yes	0	3	7
342	L:L:I42	L:L:W80	2.35	No	Yes	0	6	8
343	R:R:C291	R:R:G44	1.96	No	No	0	8	8
344	R:R:A91	R:R:P34	1.87	No	No	0	4	6
345	R:R:G47	R:R:V46	1.84	No	No	0	8	3
346	R:R:G301	R:R:V300	1.84	No	No	0	8	7
347	R:R:G106	R:R:T105	1.82	No	No	0	5	5
348	L:L:P30	L:L:T29	1.75	Yes	No	0	6	3
349	R:R:G97	R:R:M100	1.75	No	No	0	8	6
350	R:R:G173	R:R:K171	1.74	No	No	0	1	2
351	R:R:G216	R:R:K219	1.74	No	No	0	4	3
352	L:L:C38	L:L:V72	1.71	No	No	0	3	6
353	R:R:G47	R:R:L50	1.71	No	No	0	8	6
354	R:R:A156	R:R:S114	1.71	No	No	0	7	7
355	R:R:L33	R:R:P34	1.64	No	No	0	6	6
356	L:L:S86	L:L:V85	1.62	No	No	0	4	6
357	R:R:C224	R:R:K229	1.62	No	No	0	4	6
358	L:L:A48	L:L:K67	1.61	No	No	0	3	5
359	R:R:V142	R:R:V146	1.6	No	No	0	2	4
360	R:R:V146	R:R:V150	1.6	No	No	0	4	4
361	R:R:V150	R:R:V154	1.6	No	Yes	0	4	4
362	R:R:V154	R:R:V155	1.6	Yes	No	0	4	4
363	R:R:V154	R:R:V157	1.6	Yes	No	0	4	4
364	L:L:T66	L:L:V72	1.59	No	No	0	9	6
365	R:R:T239	R:R:V243	1.59	No	No	0	5	6
366	R:R:T282	R:R:V281	1.59	Yes	No	0	7	5
367	R:R:C58	R:R:N57	1.57	No	Yes	0	5	4
368	R:R:I151	R:R:V155	1.54	No	No	0	3	4
369	R:R:M241	R:R:V211	1.52	No	No	0	8	4
370	R:R:L208	R:R:V204	1.49	No	No	0	4	4
371	R:R:L221	R:R:V234	1.49	No	No	0	8	6
372	R:R:N268	R:R:S271	1.49	No	No	0	4	1
373	R:R:L309	R:R:V310	1.49	No	No	0	4	4
374	R:R:L196	R:R:T195	1.47	No	No	0	4	5
375	R:R:Q277	R:R:V25	1.43	No	No	0	1	1
376	R:R:I212	R:R:L208	1.43	No	No	0	4	4
377	L:L:F35	R:R:C269	1.4	Yes	No	0	5	6
378	R:R:A129	R:R:R140	1.38	No	Yes	0	8	6
379	R:R:L53	R:R:N57	1.37	No	Yes	0	4	4
380	R:R:L309	R:R:N306	1.37	No	No	0	4	5
381	R:R:L309	R:R:Q313	1.33	No	No	0	4	3
382	R:R:R232	R:R:V300	1.31	No	No	0	7	7
383	L:L:R68	L:L:T66	1.29	No	No	0	4	9
384	R:R:E262	R:R:Q188	1.27	No	No	0	3	2
385	R:R:E262	R:R:Q261	1.27	No	Yes	0	3	4
386	R:R:K62	R:R:R60	1.24	No	No	0	7	5
387	R:R:F45	R:R:L81	1.22	Yes	No	0	6	5
388	R:R:F78	R:R:L81	1.22	Yes	No	0	7	5
389	R:R:F247	R:R:L246	1.22	Yes	No	0	8	5
390	R:R:R232	R:R:R305	1.07	No	No	0	7	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:D28	6.5175	4	3	4
2	L:L:P30	3.9	4	0	6
3	L:L:F35	3.9225	4	0	5
4	L:L:F51	8.0925	4	1	4
5	L:L:Q56	7.795	4	3	4
6	L:L:I63	5.315	4	1	8
7	L:L:Q71	7.225	4	1	4
8	L:L:E78	10.5375	4	4	4
9	L:L:W80	11.2083	6	4	8
10	L:L:Y84	5.828	5	4	4
11	R:R:P19	4.63429	7	1	4
12	R:R:K22	4.385	4	9	3
13	R:R:Y37	10.2625	4	0	8
14	R:R:F45	4.995	4	0	6
15	R:R:N48	6.8625	4	0	9
16	R:R:L55	4.825	4	11	7
17	R:R:N57	3.255	4	0	4
18	R:R:Y68	8.07	6	2	7
19	R:R:F78	4.695	4	0	7
20	R:R:T82	5.9775	4	7	7
21	R:R:W86	7.33167	6	7	7
22	R:R:W94	9.538	5	0	9
23	R:R:F96	8.77	4	0	7
24	R:R:Y108	10.52	4	7	7
25	R:R:F112	8.1875	4	0	7
26	R:R:F113	8.5	4	13	7
27	R:R:F118	8.822	5	2	7
28	R:R:D125	8.815	4	2	8
29	R:R:R140	6.255	6	2	6
30	R:R:W153	6.928	5	2	9
31	R:R:V154	2.8375	4	0	4
32	R:R:F166	8.6325	4	6	5
33	R:R:E172	11.5675	4	1	2
34	R:R:F182	6.8425	4	6	5
35	R:R:W190	9.408	5	6	3
36	R:R:Y214	7.48	5	0	9
37	R:R:Y244	9.5125	4	5	9
38	R:R:F247	6.798	5	5	8
39	R:R:W248	10.7275	4	5	9
40	R:R:Y251	11.5	4	0	7
41	R:R:L255	7.63	4	0	6
42	R:R:Q261	4.4775	4	0	4
43	R:R:M279	4.936	5	3	5
44	R:R:T282	5.045	4	0	7
45	R:R:N293	9.735	4	10	9
46	R:R:F304	7.8825	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:D28	L:L:Q56	63.7716	10.44	Yes	Yes	3	4	4
2	L:L:Q56	R:R:M279	36.6437	5.44	Yes	Yes	3	4	5
3	R:R:L255	R:R:M279	63.9127	4.24	Yes	Yes	0	6	5
4	R:R:L255	R:R:Y251	44.2079	17.58	Yes	Yes	0	6	7
5	L:L:L25	R:R:W86	92.2221	4.56	No	Yes	0	1	7
6	R:R:W86	R:R:Y108	24.0232	5.79	Yes	Yes	7	7	7
7	R:R:E283	R:R:Y108	44.7805	8.98	No	Yes	0	6	7
8	R:R:E283	R:R:Y251	45.2079	14.59	No	Yes	0	6	7
9	L:L:L25	R:R:T105	21.4024	10.32	No	No	0	1	5
10	L:L:D28	L:L:S54	31.91	4.42	Yes	No	3	4	8
11	L:L:P30	L:L:Q56	72.1423	4.74	Yes	Yes	0	6	4
12	L:L:P30	L:L:S54	31.7165	5.34	Yes	No	0	6	8
13	L:L:C33	L:L:P30	93.4922	3.77	No	Yes	0	9	6
14	L:L:F51	L:L:I63	37.7888	6.28	Yes	Yes	1	4	8
15	L:L:I63	L:L:T53	61.6628	3.04	Yes	No	0	8	9
16	L:L:C57	L:L:T53	71.2834	5.07	No	No	0	9	9
17	L:L:C33	L:L:C57	73.1785	7.28	No	No	0	9	9
18	L:L:F51	R:R:E172	12.8906	11.66	Yes	Yes	1	4	2
19	L:L:I63	R:R:P19	17.0719	5.08	Yes	Yes	1	8	4
20	L:L:F35	L:L:S58	51.8165	6.61	Yes	No	0	5	5
21	L:L:S58	R:R:Q261	54.5744	8.66	No	Yes	0	5	4
22	R:R:L275	R:R:Q261	59.8968	3.99	No	Yes	0	5	4
23	R:R:L275	R:R:N258	65.2796	6.87	No	No	0	5	4
24	R:R:M279	R:R:N258	28.3658	5.61	Yes	No	3	5	4
25	L:L:F35	L:L:K59	46.1957	3.72	Yes	No	0	5	3
26	L:L:K59	L:L:Y37	44.7643	10.75	No	No	0	3	6
27	L:L:D75	L:L:Y37	43.3329	26.44	No	No	0	7	6
28	L:L:E78	L:L:W80	34.3091	18.54	Yes	Yes	4	4	8
29	L:L:D75	L:L:E78	40.4459	12.99	No	Yes	0	7	4
30	L:L:W80	L:L:Y84	19.2895	5.79	Yes	Yes	4	8	4
31	L:L:I42	L:L:W80	13.0156	2.35	No	Yes	0	6	8
32	L:L:I47	L:L:Y84	13.0116	4.84	No	Yes	0	7	4
33	L:L:F51	R:R:Q170	19.2008	10.54	Yes	No	1	4	1
34	R:R:L255	R:R:T195	30.2407	4.42	Yes	No	0	6	5
35	R:R:T195	R:R:T259	26.8659	12.56	No	No	0	5	5
36	R:R:K191	R:R:T259	14.3422	10.51	No	No	0	4	5
37	R:R:K191	R:R:Y187	13.8341	5.97	No	No	0	4	3
38	R:R:F182	R:R:Y187	12.0277	8.25	Yes	No	0	5	3
39	L:L:S55	R:R:F182	12.2697	6.61	No	Yes	0	7	5
40	R:R:T105	R:R:T167	14.951	6.28	No	No	0	5	5
41	R:R:S180	R:R:T167	13.3785	6.4	No	No	0	4	5
42	L:L:C33	R:R:K22	21.4064	3.23	No	Yes	0	9	3
43	R:R:K22	R:R:V25	15.0397	4.55	Yes	No	9	3	1
44	R:R:Q277	R:R:V25	12.939	1.43	No	No	0	1	1
45	R:R:I28	R:R:Q277	10.802	8.23	No	No	0	2	1
46	R:R:F79	R:R:Y108	33.0793	18.57	No	Yes	0	7	7
47	R:R:F79	R:R:M287	30.1601	7.46	No	No	0	7	8
48	R:R:M287	R:R:Y37	19.4307	8.38	No	Yes	0	8	8
49	R:R:L33	R:R:Y37	11.7536	19.93	No	Yes	0	6	8
50	R:R:M287	R:R:V83	13.6164	6.09	No	No	0	8	7
51	R:R:P84	R:R:V83	12.6164	7.07	No	No	0	9	7
52	R:R:F41	R:R:P84	11.6407	15.89	No	No	0	7	9
53	R:R:F41	R:R:L80	13.2817	3.65	No	No	0	7	6
54	R:R:G44	R:R:L80	10.6407	3.42	No	No	0	8	6
55	R:R:T82	R:R:Y108	27.2207	8.74	Yes	Yes	7	7	7
56	R:R:L107	R:R:T82	100	4.42	No	Yes	0	5	7
57	R:R:F78	R:R:L107	99.2057	8.53	Yes	No	0	7	5
58	R:R:F78	R:R:L81	74.8478	1.22	Yes	No	0	7	5
59	R:R:F45	R:R:L81	73.618	1.22	Yes	No	0	6	5
60	R:R:F112	R:R:I198	90.6254	8.79	Yes	No	0	7	5
61	R:R:F112	R:R:W248	81.6983	5.01	Yes	Yes	0	7	9
62	R:R:H289	R:R:W248	39.7726	15.87	No	Yes	5	9	9
63	R:R:F247	R:R:H289	45.2522	10.18	Yes	No	5	8	9
64	R:R:F247	R:R:I292	39.446	3.77	Yes	No	0	8	6
65	R:R:I292	R:R:I295	38.2726	4.42	No	No	0	6	6
66	R:R:F45	R:R:L77	67.6747	4.87	Yes	No	0	6	7
67	R:R:L77	R:R:N48	66.2675	4.12	No	Yes	0	7	9
68	R:R:D76	R:R:N48	31.7971	12.12	No	Yes	0	9	9
69	R:R:N48	R:R:P294	30.2044	6.52	Yes	No	0	9	9
70	R:R:F299	R:R:I295	35.9139	6.28	No	No	0	7	6
71	R:R:F299	R:R:F304	32.7406	5.36	No	Yes	0	7	8
72	R:R:F304	R:R:V51	15.7615	6.55	Yes	No	0	8	8
73	R:R:L69	R:R:V51	15.1849	4.47	No	No	0	8	8
74	R:R:A298	R:R:F304	15.7615	8.32	No	Yes	0	7	8
75	R:R:A298	R:R:L69	15.1728	4.73	No	No	0	7	8
76	R:R:L55	R:R:L69	28.8537	5.54	Yes	No	0	7	8
77	R:R:F112	R:R:F113	23.6079	13.93	Yes	Yes	0	7	7
78	R:R:F113	R:R:S160	18.1283	2.64	Yes	No	13	7	7
79	R:R:I110	R:R:S160	18.3783	4.64	No	No	0	5	7
80	R:R:I110	R:R:V157	17.2493	7.68	No	No	0	5	4
81	R:R:V154	R:R:V157	16.8421	1.6	Yes	No	0	4	4
82	R:R:V150	R:R:V154	19.2815	1.6	No	Yes	0	4	4
83	R:R:V146	R:R:V150	18.0598	1.6	No	No	0	4	4
84	R:R:V142	R:R:V146	16.8421	1.6	No	No	0	2	4
85	R:R:I67	R:R:V142	15.6768	3.07	No	No	0	7	2
86	R:R:I67	R:R:L61	14.7817	5.71	No	No	0	7	6
87	R:R:D66	R:R:L55	26.8497	4.07	No	Yes	0	8	7
88	R:R:D66	R:R:K59	24.4466	20.74	No	No	0	8	5
89	R:R:K59	R:R:Y307	19.6081	11.94	No	No	12	5	5
90	R:R:C58	R:R:Y307	17.213	8.06	No	No	0	5	5
91	R:R:C58	R:R:N57	14.7776	1.57	No	Yes	0	5	4
92	R:R:F78	R:R:W153	52.2156	4.01	Yes	Yes	0	7	9
93	R:R:F118	R:R:W153	43.8289	9.02	Yes	Yes	2	7	9
94	R:R:F118	R:R:L121	24.0958	4.87	Yes	No	2	7	6
95	R:R:L121	R:R:Y68	30.0633	12.89	No	Yes	2	6	7
96	R:R:D125	R:R:Y68	10.1448	5.75	Yes	Yes	2	8	7
97	R:R:D76	R:R:N293	28.6843	12.12	No	Yes	10	9	9
98	R:R:N293	R:R:P294	28.6884	11.4	Yes	No	0	9	9
99	R:R:W86	R:R:W94	23.1684	7.5	Yes	Yes	0	7	9
100	R:R:F96	R:R:W94	11.7939	20.04	Yes	Yes	0	7	9
101	R:R:V154	R:R:V155	25.3054	1.6	Yes	No	0	4	4
102	R:R:F117	R:R:V155	24.1442	2.62	No	No	0	5	4
103	R:R:F118	R:R:T152	18.6283	12.97	Yes	No	2	7	6
104	R:R:F117	R:R:T152	25.249	3.89	No	No	0	5	6
105	R:R:N293	R:R:Y297	54.3083	5.81	Yes	No	0	9	9
106	R:R:W248	R:R:Y244	40.1556	16.4	Yes	Yes	5	9	9
107	R:R:P206	R:R:Y244	12.1568	6.95	No	Yes	0	9	9
108	R:R:M210	R:R:Y244	34.8817	5.99	No	Yes	0	8	9
109	R:R:M210	R:R:M241	33.543	5.78	No	No	0	8	8
110	R:R:M241	R:R:Y214	30.785	4.79	No	Yes	0	8	9
111	R:R:T123	R:R:Y214	13.6406	6.24	No	Yes	0	9	9
112	R:R:C213	R:R:T123	12.1568	3.38	No	No	0	8	9
113	R:R:C213	R:R:Y127	10.6649	9.41	No	No	0	8	8
114	R:R:F182	R:R:W190	11.6326	5.01	Yes	Yes	6	5	3
115	R:R:F260	R:R:T259	13.0398	10.38	No	No	0	5	5
116	R:R:F260	R:R:L256	12.1568	2.44	No	No	0	5	5
117	R:R:L256	R:R:V199	10.6649	4.47	No	No	0	5	5
118	R:R:I296	R:R:Y297	48.0182	4.84	No	No	0	8	9
119	R:R:I240	R:R:I296	38.5872	2.94	No	No	0	8	8
120	R:R:I240	R:R:L236	35.4744	2.85	No	No	0	8	8
121	R:R:L236	R:R:V300	32.285	7.45	No	No	0	8	7
122	R:R:R232	R:R:V300	25.8901	1.31	No	No	0	7	7
123	R:R:R232	R:R:R305	19.467	1.07	No	No	0	7	8
124	R:R:E302	R:R:R305	16.2453	5.82	No	No	0	5	8
125	R:R:E302	R:R:N306	13.0116	6.57	No	No	0	5	5
126	R:R:I198	R:R:L255	90.9762	4.28	No	Yes	0	5	6
127	L:L:D28	L:L:L25	93.5607	6.79	Yes	No	0	4	1
128	L:L:S55	R:R:S180	12.5237	4.89	No	No	0	7	4
129	L:L:Q56	R:R:N258	38.0993	10.56	Yes	No	3	4	4
130	R:R:T82	R:R:W86	70.4367	4.85	Yes	Yes	7	7	7
131	R:R:F41	R:R:F45	10.7697	6.43	No	Yes	0	7	6
132	R:R:L55	R:R:L61	12.81	4.15	Yes	No	11	7	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:S24	R:R:Q194	4.33	0	No	No	5	5	0	1
L:L:S24	R:R:Y251	5.09	0	No	Yes	5	7	0	1
L:L:L25	R:R:W86	4.56	0	No	Yes	1	7	0	1
L:L:L25	R:R:T105	10.32	0	No	No	1	5	0	1
L:L:A26	R:R:W86	6.48	0	No	Yes	4	7	0	1
L:L:A27	R:R:M279	4.83	0	No	Yes	4	5	0	1
L:L:D28	R:R:S179	4.42	3	Yes	No	4	3	0	1
L:L:T29	R:R:K26	7.51	0	No	No	3	1	0	1
L:L:T29	R:R:Q280	7.09	0	No	No	3	3	0	1
L:L:T31	R:R:E172	14.11	1	No	Yes	4	2	0	1
L:L:T31	R:R:H175	4.11	1	No	No	4	1	0	1
L:L:A32	R:R:P19	3.74	1	No	Yes	4	4	0	1
L:L:A32	R:R:Q21	4.55	1	No	No	4	1	0	1
L:L:C34	R:R:P19	3.77	1	No	Yes	9	4	0	1
L:L:F35	R:R:S272	3.96	0	Yes	No	5	3	0	1
L:L:S36	R:R:S17	6.52	0	No	No	4	4	0	1
L:L:D49	R:R:K171	4.15	0	No	No	5	2	0	1
L:L:F51	R:R:Q170	10.54	1	Yes	No	4	1	0	1
L:L:F51	R:R:E172	11.66	1	Yes	Yes	4	2	0	1
L:L:E52	R:R:R168	6.98	1	No	No	3	4	0	1
L:L:E52	R:R:Q170	6.37	1	No	No	3	1	0	1
L:L:E52	R:R:H181	9.85	1	No	No	3	4	0	1
L:L:S54	R:R:S179	6.52	3	No	No	8	3	0	1
L:L:S55	R:R:S180	4.89	0	No	No	7	4	0	1
L:L:S55	R:R:F182	6.61	0	No	Yes	7	5	0	1
L:L:Q56	R:R:N258	10.56	3	Yes	No	4	4	0	1
L:L:Q56	R:R:M279	5.44	3	Yes	Yes	4	5	0	1
L:L:S58	R:R:Q261	8.66	0	No	Yes	5	4	0	1
L:L:P60	R:R:Y187	15.3	0	No	No	6	3	0	1
L:L:I63	R:R:P19	5.08	1	Yes	Yes	8	4	0	1
L:L:R70	R:R:E18	4.65	0	No	No	5	3	0	1
L:L:Q71	R:R:P19	6.32	1	Yes	Yes	4	4	0	1
L:L:Q71	R:R:Q21	6.4	1	Yes	No	4	1	0	1
L:L:C73	R:R:P19	5.65	1	No	Yes	9	4	0	1
L:L:P76	R:R:Y184	9.74	0	No	No	9	1	0	1
L:L:Q82	R:R:Y184	12.4	0	No	No	7	1	0	1
R:R:P19	R:R:Q21	4.74	1	Yes	No	4	1	1	1
R:R:C20	R:R:C269	7.28	0	No	No	9	6	2	1
R:R:K22	R:R:V25	4.55	9	Yes	No	3	1	1	2
R:R:K22	R:R:N273	6.99	9	Yes	No	3	1	1	2
R:R:N273	R:R:V25	5.91	9	No	No	1	1	2	2
R:R:A29	R:R:Q280	4.55	0	No	No	5	3	2	1
R:R:T82	R:R:W86	4.85	7	Yes	Yes	7	7	2	1
R:R:L104	R:R:T82	5.9	7	No	Yes	5	7	2	2
R:R:T82	R:R:Y108	8.74	7	Yes	Yes	7	7	2	2
R:R:W86	R:R:W94	7.5	7	Yes	Yes	7	9	1	2
R:R:L104	R:R:W86	14.81	7	No	Yes	5	7	2	1
R:R:W86	R:R:Y108	5.79	7	Yes	Yes	7	7	1	2
R:R:N98	R:R:R168	4.82	0	No	No	3	4	2	1
R:R:T105	R:R:T167	6.28	0	No	No	5	5	1	2
R:R:E283	R:R:Y108	8.98	0	No	Yes	6	7	2	2
R:R:F166	R:R:F182	7.5	6	Yes	Yes	5	5	2	1
R:R:F166	R:R:W190	16.04	6	Yes	Yes	5	3	2	2
R:R:S180	R:R:T167	6.4	0	No	No	4	5	1	2
R:R:H181	R:R:R168	16.93	1	No	No	4	4	1	1
R:R:H181	R:R:Q170	16.07	1	No	No	4	1	1	1
R:R:K171	R:R:Y176	10.75	0	No	No	2	4	1	2
R:R:E172	R:R:H175	17.23	1	Yes	No	2	1	1	1
R:R:F182	R:R:Y187	8.25	6	Yes	No	5	3	1	1
R:R:F182	R:R:W190	5.01	6	Yes	Yes	5	3	1	2
R:R:K191	R:R:Y187	5.97	0	No	No	4	3	2	1
R:R:I198	R:R:Q194	4.12	0	No	No	5	5	2	1
R:R:I198	R:R:L255	4.28	0	No	Yes	5	6	2	2
R:R:L255	R:R:Y251	17.58	0	Yes	Yes	6	7	2	1
R:R:T282	R:R:Y251	8.74	0	Yes	Yes	7	7	2	1
R:R:E283	R:R:Y251	14.59	0	No	Yes	6	7	2	1
R:R:M279	R:R:V254	4.56	3	Yes	No	5	5	1	2
R:R:T282	R:R:V254	6.35	0	Yes	No	7	5	2	2
R:R:L255	R:R:M279	4.24	0	Yes	Yes	6	5	2	1
R:R:L275	R:R:N258	6.87	0	No	No	5	4	2	1
R:R:M279	R:R:N258	5.61	3	Yes	No	5	4	1	1
R:R:L266	R:R:Q261	3.99	0	No	Yes	4	4	2	1
R:R:L275	R:R:Q261	3.99	0	No	Yes	5	4	2	1
R:R:E172	R:R:G173	3.27	1	Yes	No	2	1	1	2
L:L:C33	R:R:K22	3.23	0	No	Yes	9	3	0	1
R:R:E18	R:R:P19	3.14	0	No	Yes	3	4	1	1
L:L:S58	R:R:N267	2.98	0	No	No	5	3	0	1
R:R:D276	R:R:K22	2.77	0	No	Yes	4	3	2	1
R:R:G106	R:R:T105	1.82	0	No	No	5	5	2	1
R:R:G173	R:R:K171	1.74	0	No	No	1	2	2	1
L:L:F35	R:R:C269	1.4	0	Yes	No	5	6	0	1
R:R:E262	R:R:Q261	1.27	0	No	Yes	3	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7F1Q_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.72
Number of Linked Nodes	349
Number of Links	390
Number of Hubs	46
Number of Links mediated by Hubs	175
Number of Communities	14
Number of Nodes involved in Communities	76
Number of Links involved in Communities	95

Path Summary
Number Of Nodes in MetaPath	133
Number Of Links MetaPath	132
Number of Shortest Paths	81137
Length Of Smallest Path	3
Average Path Length	16.7311
Length of Longest Path	40
Minimum Path Strength	1.22
Average Path Strength	6.79055
Maximum Path Strength	20.77
Minimum Path Correlation	0.7
Average Path Correlation	0.937282
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	52.0073
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.6807
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body • CCR5 chemokine receptor binding • CCR chemokine receptor binding • cytokine receptor binding • chemokine receptor binding • kinase activity • transferase activity • transferase activity, transferring phosphorus-containing groups • catalytic activity, acting on a protein • protein kinase activity • phosphotransferase activity, alcohol group as acceptor • identical protein binding • molecular function activator activity • signaling receptor activator activity • chemokine activity • cytokine activity • signaling receptor regulator activity • receptor ligand activity • CCR1 chemokine receptor binding • chemoattractant activity • enzyme activator activity • phospholipase activator activity • lipase activator activity • virus receptor activity • exogenous protein binding • molecular transducer activity • coreceptor activity • signaling receptor activity • phosphoric ester hydrolase activity • phospholipase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • glycerophospholipase activity • C-type glycerophospholipase activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • lipase activity • G protein-coupled chemoattractant receptor activity • C-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • cytokine receptor activity • immune receptor activity • cytoskeletal protein binding • actin binding • C-C chemokine binding • chemokine binding • cytokine binding • chemokine (C-C motif) ligand 5 binding • positive regulation of cell communication • positive regulation of signal transduction • regulation of signal transduction • positive regulation of response to stimulus • regulation of intracellular signal transduction • regulation of calcium-mediated signaling • positive regulation of calcium-mediated signaling • positive regulation of intracellular signal transduction • regulation of response to stimulus • calcium-mediated signaling • positive regulation of signaling • cellular developmental process • glial cell migration • nervous system development • neurogenesis • gliogenesis • cell differentiation • astrocyte cell migration • cell activation • regulation of defense response • regulation of response to external stimulus • defense response • response to external stimulus • regulation of inflammatory response • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • positive regulation of locomotion • regulation of cell motility • regulation of microglial cell migration • macrophage migration • regulation of glial cell migration • positive regulation of cell migration • regulation of macrophage migration • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • positive regulation of microglial cell migration • regulation of immune system process • regulation of mononuclear cell migration • positive regulation of immune system process • locomotion • positive regulation of macrophage migration • regulation of leukocyte migration • microglial cell migration • positive regulation of leukocyte migration • positive regulation of glial cell migration • regulation of locomotion • positive regulation of chemotaxis • regulation of lymphocyte chemotaxis • natural killer cell chemotaxis • taxis • positive regulation of natural killer cell chemotaxis • chemotaxis • regulation of leukocyte chemotaxis • positive regulation of lymphocyte migration • positive regulation of leukocyte chemotaxis • regulation of natural killer cell chemotaxis • lymphocyte chemotaxis • regulation of lymphocyte migration • positive regulation of lymphocyte chemotaxis • cell chemotaxis • regulation of chemotaxis • leukocyte chemotaxis • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • positive regulation of macromolecule biosynthetic process • regulation of gene expression • positive regulation of gene expression • regulation of macromolecule biosynthetic process • positive regulation of macromolecule metabolic process • macromolecule metabolic process • neutrophil chemotaxis • neutrophil migration • granulocyte migration • granulocyte chemotaxis • response to sterol • response to cholesterol • neuron apoptotic process • positive regulation of programmed cell death • regulation of apoptotic process • regulation of programmed cell death • cell death • positive regulation of apoptotic process • apoptotic process • positive regulation of neuron apoptotic process • programmed cell death • regulation of neuron apoptotic process • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • myeloid leukocyte differentiation • regulation of leukocyte differentiation • regulation of developmental process • cell development • regulation of cell differentiation • regulation of cell development • regulation of osteoclast differentiation • osteoclast differentiation • negative regulation of cell differentiation • negative regulation of hemopoiesis • regulation of multicellular organismal development • negative regulation of leukocyte differentiation • hemopoiesis • regulation of myeloid cell differentiation • negative regulation of developmental process • regulation of myeloid leukocyte differentiation • negative regulation of myeloid cell differentiation • negative regulation of osteoclast differentiation • negative regulation of myeloid leukocyte differentiation • negative regulation of cell development • myeloid cell differentiation • negative regulation of immune system process • regulation of hemopoiesis • negative regulation of multicellular organismal process • leukocyte differentiation • response to toxic substance • regulation of behavior • behavior • interleukin-1 production • regulation of interleukin-1 beta production • positive regulation of interleukin-1 beta production • regulation of cytokine production • cytokine production • positive regulation of interleukin-1 production • regulation of interleukin-1 production • interleukin-1 beta production • positive regulation of cytokine production • MAPK cascade • regulation of macrophage activation • positive regulation of macrophage activation • regulation of leukocyte activation • positive regulation of microglial cell activation • regulation of cell activation • positive regulation of neuroinflammatory response • myeloid leukocyte activation • leukocyte activation • macrophage activation • positive regulation of cell activation • leukocyte activation involved in inflammatory response • regulation of neuroinflammatory response • positive regulation of leukocyte activation • microglial cell activation • glial cell activation • regulation of microglial cell activation • neuroinflammatory response • regulated exocytosis • cellular localization • eosinophil activation • cell activation involved in immune response • leukocyte degranulation • myeloid leukocyte mediated immunity • vesicle-mediated transport • establishment of localization in cell • leukocyte activation involved in immune response • eosinophil degranulation • leukocyte mediated immunity • eosinophil activation involved in immune response • immune response • myeloid cell activation involved in immune response • immune effector process • exocytosis • eosinophil mediated immunity • granulocyte activation • regulation of calcium ion import • regulation of calcium ion transport • positive regulation of calcium ion transport • positive regulation of calcium ion import • regulation of monoatomic ion transport • calcium ion transport • metal ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • monoatomic ion transport • calcium ion import • monoatomic cation transport • regulation of metal ion transport • eosinophil chemotaxis • eosinophil migration • biological process involved in interspecies interaction between organisms • host-mediated suppression of viral proces • host-mediated perturbation of viral transcription • host-mediated suppression of viral transcription • host-mediated perturbation of viral process • modulation of process of another organism • host-mediated perturbation of symbiont process • cellular response to interleukin-1 • response to interleukin-1 • ossification • osteoblast differentiation • positive regulation of ERK1 and ERK2 cascade • positive regulation of MAPK cascade • regulation of MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • sensory perception of pain • regulation of nervous system process • regulation of sensory perception • regulation of sensory perception of pain • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • regulation of cell shape • cell morphogenesis • regulation of cell morphogenesis • anatomical structure morphogenesis • regulation of anatomical structure morphogenesis • cellular response to tumor necrosis factor • response to tumor necrosis factor • response to other organism • response to type II interferon • defense response to symbiont • cellular response to type II interferon • response to biotic stimulus • defense response to other organism • innate immune response • response to external biotic stimulus • monocyte chemotaxis • humoral immune response • antimicrobial humoral response • antimicrobial humoral immune response mediated by antimicrobial peptide • macrophage chemotaxis • negative regulation of metabolic process • negative regulation of gene expression • negative regulation of biosynthetic process • negative regulation of macromolecule biosynthetic process • negative regulation of macromolecule metabolic process • regulation of tumor necrosis factor production • positive regulation of tumor necrosis factor superfamily cytokine production • tumor necrosis factor superfamily cytokine production • positive regulation of tumor necrosis factor production • tumor necrosis factor production • regulation of tumor necrosis factor superfamily cytokine production • release of sequestered calcium ion into cytosol by endoplasmic reticulum • calcium ion transmembrane import into cytosol • monoatomic ion transmembrane transport • sarcoplasmic reticulum calcium ion transport • release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • monoatomic cation transmembrane transport • transmembrane transport • release of sequestered calcium ion into cytosol • calcium ion transmembrane transport • T cell chemotaxis • negative regulation of biomineral tissue development • regulation of biomineral tissue development • regulation of bone mineralization • negative regulation of bone mineralization • biomineral tissue development • bone mineralization • tissue development • negative regulation of ossification • regulation of ossification • leukocyte apoptotic process • macrophage apoptotic process • negative regulation of leukocyte apoptotic process • myeloid cell apoptotic process • regulation of leukocyte apoptotic process • negative regulation of programmed cell death • negative regulation of macrophage apoptotic process • negative regulation of apoptotic process • regulation of macrophage apoptotic process • inflammatory cell apoptotic process • negative regulation of myeloid cell apoptotic process • regulation of myeloid cell apoptotic process • positive regulation of cytosolic calcium ion concentration • cellular response to lipopolysaccharide • cellular response to molecule of bacterial origin • response to lipopolysaccharide • cellular response to biotic stimulus • response to bacterium • response to molecule of bacterial origin • dendritic cell chemotaxis • dendritic cell migration • cellular defense response • cell surface • external side of plasma membrane • endosome • intracellular vesicle • cytoplasmic vesicle
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • G protein-coupled receptor-like • Interleukin 8-like chemokines
SCOP2	Family Identifier	• Ras-like P-loop GTPases • G protein-coupled receptor-like • Interleukin 8-like chemokines
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	CCL3
UniProt	P10147
Sequence	>7F1Q_nogp_Chain_L S L A A D T P T A C C F S Y C S R Q I P Q N F I A D Y F E T S S Q C S K P G V I F L T K R S R Q V C A D P S E E W V Q K Y V S D L E L S A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P51681
Sequence	>7F1Q_nogp_Chain_R S E P C Q K I N V K Q I A A R L L P P L Y S L V F I F G F V G N M L V I L I L I N C K R L K S M T D I Y L L N L A I S D L F F L L T V P F W A H Y A A A Q W D F G N T M C Q L L T G L Y F I G F F S G I F F I I L L T I D R Y L A V V H A V F A L K A R T V T F G V V T S V I T W V V A V F A S L P N I I F T R S Q K E G L H Y T C S S H F P Y S Q Y Q F W K N F Q T L K I V I L G L V L P L L V M V I C Y S G I L K T L L R C R N E K K R H R A V R L I F T I M I V Y F L F W A P Y N I V L L L N T F Q E F F G L N N C S S S N R L D Q A M Q V T E T L G M T H C C I N P I I Y A F V G E K F R N Y L L V F F Q Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4MBS	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.71	2013-09-11	doi.org/10.1126/science.1241475
	5UIW	A	Protein	Chemokine	CCR5	Homo sapiens	5P7-CCL5	-	-	2.2	2017-06-28	doi.org/10.1016/j.immuni.2017.05.002
	6AKX	A	Protein	Chemokine	CCR5	Homo sapiens	-	A4R	-	2.8	2018-10-24	doi.org/10.1021/acs.jmedchem.8b01077
	6AKY	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.8	2018-10-24	doi.org/10.1021/acs.jmedchem.8b01077
	6MEO	A	Protein	Chemokine	CCR5	Homo sapiens	Gp160; CD4	-	-	3.9	2018-12-12	doi.org/10.1038/s41586-018-0804-9
	6MET	A	Protein	Chemokine	CCR5	Homo sapiens	Gp160; CD4	-	-	4.5	2018-12-12	doi.org/10.1038/s41586-018-0804-9
	7O7F	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-	Gi1/β1/γ1	3.15	2021-06-30	doi.org/10.1126/sciadv.abg8685
	7O7F (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-		3.15	2021-06-30	doi.org/10.1126/sciadv.abg8685
	7F1Q	A	Protein	Chemokine	CCR5	Homo sapiens	CCL3	-	Gi1/β1/γ2	2.9	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1Q (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	CCL3	-		2.9	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1R	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	3	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1R (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		3	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1S	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	2.8	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1S (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		2.8	2021-07-14	doi.org/10.1038/s41467-021-24438-5
	7F1T	A	Protein	Chemokine	CCR5	Homo sapiens	CCL3	-	-	2.6	2021-07-14	doi.org/10.1038/s41467-021-24438-5

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