psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:R48	R:R:T16	5.17	Yes	No	0	0	2
2	R:R:E18	R:R:P19	4.72	Yes	No	0	3	4
3	L:L:R48	R:R:E18	6.98	Yes	Yes	0	0	3
4	R:R:C20	R:R:C269	7.28	No	No	0	9	6
5	R:R:K22	R:R:K26	7.18	Yes	No	1	3	1
6	R:R:K22	R:R:N273	8.39	Yes	No	0	3	1
7	L:L:V8	R:R:K22	7.59	Yes	Yes	1	0	3
8	R:R:Q277	R:R:V25	8.6	No	No	0	1	1
9	L:L:D6	R:R:K26	13.83	Yes	No	1	0	1
10	L:L:V8	R:R:K26	4.55	Yes	No	1	0	1
11	R:R:I28	R:R:Q27	5.49	No	No	0	2	2
12	R:R:A29	R:R:Q280	4.55	No	No	0	5	3
13	L:L:D6	R:R:A30	4.63	Yes	No	0	0	4
14	R:R:L32	R:R:R31	6.07	No	No	0	6	3
15	R:R:L32	R:R:L36	5.54	No	No	0	6	6
16	R:R:L33	R:R:Y37	7.03	No	Yes	0	6	8
17	R:R:L33	R:R:Q280	3.99	No	No	0	6	3
18	R:R:P34	R:R:P35	5.84	No	No	0	6	5
19	R:R:A90	R:R:P34	5.61	No	No	0	5	6
20	R:R:V83	R:R:Y37	5.05	No	Yes	5	7	8
21	R:R:M287	R:R:Y37	4.79	Yes	Yes	5	8	8
22	R:R:F43	R:R:L39	4.87	No	No	0	5	5
23	R:R:M287	R:R:V40	9.13	Yes	No	0	8	7
24	R:R:C291	R:R:V40	3.42	No	No	0	8	7
25	R:R:F41	R:R:I42	3.77	No	No	0	7	5
26	R:R:F41	R:R:F45	9.65	No	Yes	0	7	6
27	R:R:F41	R:R:P84	11.56	No	No	0	7	9
28	R:R:F43	R:R:I42	7.54	No	No	0	5	5
29	R:R:F45	R:R:M49	3.73	Yes	No	0	6	3
30	R:R:G47	R:R:V46	3.68	No	No	0	8	3
31	R:R:D76	R:R:N48	9.42	No	No	0	9	9
32	R:R:N48	R:R:P294	9.77	No	No	0	9	9
33	R:R:F304	R:R:V51	5.24	Yes	No	0	8	8
34	R:R:I52	R:R:L77	5.71	No	No	0	7	7
35	R:R:F304	R:R:I54	8.79	Yes	No	0	8	7
36	R:R:F311	R:R:I54	5.02	Yes	No	0	4	7
37	R:R:L55	R:R:L70	6.92	No	No	0	7	6
38	R:R:I56	R:R:N57	5.66	No	No	0	3	4
39	R:R:I56	R:R:R60	3.76	No	No	0	3	5
40	R:R:F311	R:R:N57	4.83	Yes	No	0	4	4
41	R:R:C58	R:R:F311	4.19	No	Yes	0	5	4
42	R:R:K59	R:R:K62	8.62	No	No	0	5	7
43	R:R:F304	R:R:K59	4.96	Yes	No	0	8	5
44	R:R:K59	R:R:Y307	15.53	No	No	0	5	5
45	R:R:L61	R:R:R60	12.15	No	No	0	6	5
46	R:R:D66	R:R:K62	13.83	No	No	0	8	7
47	R:R:R140	R:R:S63	10.54	Yes	No	0	6	7
48	R:R:M64	R:R:Y68	9.58	Yes	Yes	2	6	7
49	R:R:D125	R:R:M64	4.16	Yes	Yes	2	8	6
50	R:R:F144	R:R:M64	4.98	No	Yes	0	3	6
51	R:R:G145	R:R:M64	3.49	No	Yes	2	7	6
52	R:R:L122	R:R:T65	4.42	No	No	0	9	8
53	R:R:D125	R:R:T65	10.12	Yes	No	0	8	8
54	R:R:L121	R:R:Y68	5.86	No	Yes	2	6	7
55	R:R:D125	R:R:Y68	3.45	Yes	Yes	2	8	7
56	R:R:G145	R:R:Y68	4.35	No	Yes	2	7	7
57	R:R:T148	R:R:Y68	3.75	No	Yes	2	6	7
58	R:R:I74	R:R:L70	4.28	No	No	0	6	6
59	R:R:F118	R:R:N71	14.5	Yes	No	0	7	9
60	R:R:N71	R:R:S149	4.47	No	No	0	9	7
61	R:R:L72	R:R:N293	6.87	No	No	0	9	9
62	R:R:F78	R:R:I74	5.02	No	No	0	7	6
63	R:R:G111	R:R:S75	3.71	No	No	0	8	8
64	R:R:S114	R:R:S75	6.52	No	No	0	7	8
65	R:R:G115	R:R:S75	3.71	No	No	0	9	8
66	R:R:C290	R:R:D76	9.34	No	No	0	8	9
67	R:R:F78	R:R:L107	4.87	No	No	0	7	5
68	R:R:F79	R:R:Y108	12.38	Yes	No	0	7	7
69	R:R:F112	R:R:F79	5.36	No	Yes	0	7	7
70	R:R:F79	R:R:M287	3.73	Yes	Yes	0	7	8
71	R:R:C290	R:R:F79	11.17	No	Yes	0	8	7
72	R:R:L80	R:R:M287	7.07	No	Yes	0	6	8
73	R:R:L107	R:R:T82	5.9	No	No	0	5	7
74	R:R:P84	R:R:V83	3.53	No	No	0	9	7
75	R:R:M287	R:R:V83	7.61	Yes	No	5	8	7
76	R:R:F85	R:R:F96	6.43	No	Yes	0	6	7
77	R:R:F85	R:R:L104	12.18	No	No	0	6	5
78	R:R:W86	R:R:Y89	8.68	Yes	Yes	1	7	4
79	R:R:T105	R:R:W86	3.64	Yes	Yes	1	5	7
80	R:R:C178	R:R:W86	6.53	Yes	Yes	1	9	7
81	L:L:P3	R:R:W86	12.16	No	Yes	1	0	7
82	L:L:P4	R:R:W86	16.21	No	Yes	0	0	7
83	L:L:I7	R:R:W86	4.7	Yes	Yes	1	0	7
84	R:R:F96	R:R:H88	5.66	Yes	No	0	7	5
85	R:R:W94	R:R:Y89	9.65	Yes	Yes	1	9	4
86	R:R:C178	R:R:Y89	4.03	Yes	Yes	1	9	4
87	L:L:D6	R:R:Y89	9.2	Yes	Yes	1	0	4
88	L:L:I7	R:R:Y89	6.04	Yes	Yes	1	0	4
89	R:R:H175	R:R:Q93	13.6	No	No	0	1	3
90	R:R:F96	R:R:W94	19.04	Yes	Yes	0	7	9
91	R:R:C101	R:R:W94	7.84	No	Yes	1	9	9
92	R:R:S169	R:R:W94	4.94	Yes	Yes	1	4	9
93	R:R:C178	R:R:W94	19.59	Yes	Yes	1	9	9
94	R:R:F96	R:R:M100	3.73	Yes	No	0	7	6
95	R:R:G97	R:R:K171	3.49	No	No	0	8	2
96	R:R:N98	R:R:Q102	7.92	No	No	0	3	7
97	R:R:N98	R:R:S169	4.47	No	Yes	0	3	4
98	R:R:C101	R:R:S169	3.44	No	Yes	1	9	4
99	R:R:C101	R:R:C178	7.28	No	Yes	1	9	9
100	R:R:Q102	R:R:T167	4.25	No	No	0	7	5
101	R:R:F109	R:R:T105	3.89	No	Yes	0	5	5
102	R:R:T105	R:R:T167	10.99	Yes	No	0	5	5
103	L:L:P3	R:R:T105	5.25	No	Yes	1	0	5
104	R:R:G106	R:R:I164	3.53	No	No	0	5	4
105	R:R:F109	R:R:Y108	8.25	No	No	0	5	7
106	L:L:P4	R:R:Y108	16.69	No	No	0	0	7
107	R:R:G111	R:R:I110	3.53	No	No	0	8	5
108	R:R:I110	R:R:S160	6.19	No	No	0	5	7
109	R:R:F112	R:R:W248	7.02	No	Yes	0	7	9
110	R:R:F113	R:R:F117	5.36	No	Yes	8	7	5
111	R:R:F113	R:R:K197	6.2	No	Yes	0	7	3
112	R:R:F113	R:R:L201	3.65	No	No	8	7	4
113	R:R:F118	R:R:S114	7.93	Yes	No	6	7	7
114	R:R:S114	R:R:W153	12.36	No	No	6	7	9
115	R:R:I116	R:R:Y244	4.84	No	No	7	7	9
116	R:R:I116	R:R:W248	3.52	No	Yes	7	7	9
117	R:R:F117	R:R:T152	5.19	Yes	No	0	5	6
118	R:R:F117	R:R:L201	4.87	Yes	No	8	5	4
119	R:R:F118	R:R:T152	5.19	Yes	No	0	7	6
120	R:R:F118	R:R:W153	7.02	Yes	No	6	7	9
121	R:R:I119	R:R:N293	7.08	No	No	0	8	9
122	R:R:I120	R:R:P206	3.39	No	Yes	0	7	9
123	R:R:I120	R:R:V209	4.61	No	No	0	7	6
124	R:R:L121	R:R:T148	4.42	No	No	2	6	6
125	R:R:L121	R:R:T152	4.42	No	No	0	6	6
126	R:R:L122	R:R:Y297	8.21	No	Yes	0	9	9
127	R:R:M210	R:R:T123	6.02	No	No	0	8	9
128	R:R:C213	R:R:T123	3.38	No	No	0	8	9
129	R:R:T123	R:R:Y214	6.24	No	Yes	0	9	9
130	R:R:D125	R:R:R140	11.91	Yes	Yes	0	8	6
131	R:R:R126	R:R:Y214	6.17	No	Yes	0	9	9
132	R:R:R126	R:R:Y297	6.17	No	Yes	0	9	9
133	R:R:V131	R:R:Y127	12.62	No	No	0	7	8
134	R:R:C213	R:R:Y127	6.72	No	No	0	8	8
135	R:R:A136	R:R:L128	4.73	No	No	0	5	5
136	R:R:A129	R:R:R140	5.53	No	Yes	0	8	6
137	R:R:I217	R:R:V130	4.61	No	No	0	8	8
138	R:R:T220	R:R:V130	4.76	No	No	0	5	8
139	R:R:H132	R:R:V131	4.15	No	No	0	6	7
140	R:R:T220	R:R:V131	4.76	No	No	0	5	7
141	R:R:F144	R:R:T148	7.78	No	No	0	3	6
142	R:R:F158	R:R:V154	5.24	No	No	0	4	4
143	R:R:F166	R:R:I165	10.05	Yes	No	0	5	3
144	R:R:F166	R:R:S180	3.96	Yes	No	0	5	4
145	R:R:F166	R:R:F182	4.29	Yes	Yes	4	5	5
146	R:R:F166	R:R:P183	10.11	Yes	No	4	5	3
147	R:R:F166	R:R:W190	11.02	Yes	Yes	4	5	3
148	R:R:S180	R:R:T167	4.8	No	No	0	4	5
149	R:R:Q170	R:R:R168	8.18	No	No	9	1	4
150	R:R:H181	R:R:R168	10.16	No	No	9	4	4
151	R:R:K171	R:R:S169	4.59	No	Yes	0	2	4
152	R:R:H181	R:R:Q170	7.42	No	No	9	4	1
153	R:R:K171	R:R:Y176	4.78	No	No	0	2	4
154	L:L:F29	R:R:E172	22.15	No	No	0	0	2
155	L:L:L9	R:R:T177	5.9	No	No	0	0	2
156	L:L:Y30	R:R:H181	4.36	No	No	0	0	4
157	R:R:F182	R:R:Y187	7.22	Yes	Yes	0	5	3
158	R:R:F182	R:R:W190	5.01	Yes	Yes	4	5	3
159	R:R:F182	R:R:Q194	7.03	Yes	No	0	5	5
160	R:R:P183	R:R:W190	4.05	No	Yes	4	3	3
161	L:L:P54	R:R:Y184	9.74	No	No	0	0	1
162	L:L:E55	R:R:Y184	6.73	No	No	0	0	1
163	L:L:E55	R:R:S185	4.31	No	No	0	0	3
164	R:R:Q186	R:R:W190	5.48	No	Yes	0	3	3
165	R:R:K191	R:R:Y187	7.17	No	Yes	0	4	3
166	L:L:G33	R:R:Y187	4.35	No	Yes	0	0	3
167	L:L:P38	R:R:Y187	15.3	No	Yes	0	0	3
168	R:R:K191	R:R:Q188	4.07	No	No	0	4	2
169	R:R:F189	R:R:W190	16.04	No	Yes	0	1	3
170	R:R:F193	R:R:W190	9.02	No	Yes	0	3	3
171	R:R:N192	R:R:T259	5.85	No	No	0	3	5
172	R:R:K197	R:R:Q194	6.78	Yes	No	0	3	5
173	L:L:?1	R:R:Q194	7.12	Yes	No	0	0	5
174	R:R:T195	R:R:T259	12.56	No	No	0	5	5
175	L:L:?1	R:R:T195	7.88	Yes	No	0	0	5
176	R:R:I198	R:R:L255	5.71	No	Yes	0	5	6
177	R:R:I200	R:R:V204	4.61	Yes	No	0	5	4
178	R:R:L203	R:R:N252	10.98	No	No	0	8	8
179	R:R:P206	R:R:Y244	8.34	Yes	No	0	9	9
180	R:R:F245	R:R:L207	3.65	No	No	0	5	6
181	R:R:I237	R:R:Y214	6.04	No	Yes	0	8	9
182	R:R:I240	R:R:Y214	6.04	No	Yes	0	8	9
183	R:R:M241	R:R:Y214	7.18	No	Yes	0	8	9
184	R:R:L218	R:R:V234	4.47	No	No	0	4	6
185	R:R:I237	R:R:L218	7.14	No	No	0	8	4
186	R:R:F238	R:R:L218	3.65	No	No	0	5	4
187	R:R:K229	R:R:N226	8.39	No	No	0	6	4
188	R:R:E227	R:R:R230	8.14	No	No	0	3	7
189	R:R:I240	R:R:L236	4.28	No	No	0	8	8
190	R:R:L236	R:R:V300	7.45	No	No	0	8	7
191	R:R:W248	R:R:Y244	8.68	Yes	No	7	9	9
192	R:R:A249	R:R:F245	5.55	No	No	0	6	5
193	R:R:F247	R:R:L246	4.87	No	No	0	8	5
194	R:R:F247	R:R:T288	6.49	No	No	0	8	5
195	R:R:F247	R:R:H289	9.05	No	No	0	8	9
196	R:R:G286	R:R:W248	5.63	No	Yes	0	8	9
197	R:R:H289	R:R:W248	14.81	No	Yes	0	9	9
198	R:R:P250	R:R:T282	3.5	No	No	0	9	7
199	R:R:N252	R:R:Y251	3.49	No	Yes	0	8	7
200	R:R:L255	R:R:Y251	14.07	Yes	Yes	0	6	7
201	R:R:T282	R:R:Y251	8.74	No	Yes	0	7	7
202	R:R:E283	R:R:Y251	12.35	No	Yes	0	6	7
203	R:R:M279	R:R:V254	9.13	No	No	0	5	5
204	R:R:L255	R:R:M279	5.65	Yes	No	0	6	5
205	L:L:?1	R:R:L255	8.88	Yes	Yes	0	0	6
206	R:R:F264	R:R:L257	4.87	No	No	0	1	4
207	R:R:L257	R:R:L266	4.15	No	No	0	4	4
208	R:R:L257	R:R:L275	5.54	No	No	0	4	5
209	R:R:N258	R:R:Q261	3.96	No	Yes	11	4	4
210	R:R:L275	R:R:N258	5.49	No	No	11	5	4
211	R:R:M279	R:R:N258	4.21	No	No	0	5	4
212	R:R:F260	R:R:T259	5.19	No	No	0	5	5
213	R:R:F260	R:R:F263	12.86	No	No	0	5	1
214	R:R:L266	R:R:Q261	3.99	No	Yes	0	4	4
215	R:R:Q261	R:R:S272	5.78	Yes	No	0	4	3
216	R:R:L275	R:R:Q261	6.65	No	Yes	11	5	4
217	R:R:L266	R:R:S271	7.51	No	No	0	4	1
218	R:R:N267	R:R:N268	4.09	No	No	0	3	4
219	R:R:N268	R:R:S271	4.47	No	No	0	4	1
220	R:R:C269	R:R:N273	4.72	No	No	0	6	1
221	L:L:F13	R:R:S272	3.96	No	No	0	0	3
222	L:L:V8	R:R:D276	14.61	Yes	No	0	0	4
223	L:L:V8	R:R:Q280	5.73	Yes	No	0	0	3
224	L:L:P4	R:R:E283	4.72	No	No	0	0	6
225	R:R:C291	R:R:I292	4.91	No	No	0	8	6
226	R:R:N293	R:R:Y297	5.81	No	Yes	0	9	9
227	R:R:F299	R:R:I295	6.28	No	No	0	7	6
228	R:R:I296	R:R:Y297	3.63	No	Yes	0	8	9
229	R:R:F299	R:R:F304	6.43	No	Yes	0	7	8
230	R:R:F299	R:R:L308	3.65	No	No	0	7	6
231	R:R:E302	R:R:F304	5.83	No	Yes	0	5	8
232	L:L:?1	L:L:G2	7.32	Yes	No	0	0	0
233	L:L:?1	L:L:K34	10.56	Yes	No	0	0	0
234	L:L:G2	L:L:P3	4.06	No	No	0	0	0
235	L:L:G5	L:L:I7	3.53	No	Yes	0	0	0
236	L:L:D6	L:L:I7	4.2	Yes	Yes	1	0	0
237	L:L:C11	L:L:C35	7.28	No	No	0	0	0
238	L:L:A39	L:L:C12	3.61	No	No	0	0	0
239	L:L:C12	L:L:C51	7.28	No	No	0	0	0
240	L:L:N53	L:L:Y15	9.3	Yes	No	0	0	0
241	L:L:P19	L:L:W58	18.92	No	Yes	3	0	0
242	L:L:P19	L:L:Y62	6.95	No	Yes	3	0	0
243	L:L:L20	L:L:P21	4.93	No	No	0	0	0
244	L:L:R22	L:L:Y62	13.38	No	Yes	0	0	0
245	L:L:R22	L:L:S65	7.91	No	No	0	0	0
246	L:L:H24	L:L:T44	4.11	No	No	0	0	0
247	L:L:H24	L:L:R45	13.54	No	No	0	0	0
248	L:L:F42	L:L:I25	5.02	No	No	0	0	0
249	L:L:K26	L:L:N47	4.2	No	No	0	0	0
250	L:L:V40	L:L:Y28	5.05	Yes	Yes	12	0	0
251	L:L:F42	L:L:Y28	4.13	No	Yes	12	0	0
252	L:L:L66	L:L:Y28	7.03	No	Yes	0	0	0
253	L:L:F29	L:L:V41	14.42	No	No	10	0	0
254	L:L:F29	L:L:Q49	8.2	No	Yes	10	0	0
255	L:L:V40	L:L:Y30	5.05	Yes	No	0	0	0
256	L:L:K34	L:L:S32	4.59	No	No	0	0	0
257	L:L:C35	L:L:S32	3.44	No	No	0	0	0
258	L:L:N37	L:L:S36	5.96	No	No	0	0	0
259	L:L:F42	L:L:V40	5.24	No	Yes	12	0	0
260	L:L:Q49	L:L:V41	5.73	Yes	No	10	0	0
261	L:L:K46	L:L:T44	9.01	No	No	0	0	0
262	L:L:K46	L:L:R48	13.61	No	Yes	0	0	0
263	L:L:A52	L:L:V59	5.09	No	No	0	0	0
264	L:L:N53	L:L:P54	6.52	Yes	No	0	0	0
265	L:L:E55	L:L:N53	3.94	No	Yes	0	0	0
266	L:L:K56	L:L:N53	4.2	No	Yes	0	0	0
267	L:L:K56	L:L:W58	9.28	No	Yes	3	0	0
268	L:L:K56	L:L:V59	6.07	No	No	3	0	0
269	L:L:V59	L:L:W58	12.26	No	Yes	3	0	0
270	L:L:W58	L:L:Y62	7.72	Yes	Yes	3	0	0
271	L:L:N64	L:L:R60	9.64	No	No	0	0	0
272	L:L:E61	L:L:Y62	4.49	No	Yes	0	0	0
273	R:R:L205	R:R:P206	3.28	No	Yes	0	6	9
274	L:L:S32	R:R:S179	3.26	No	No	0	0	3
275	R:R:A73	R:R:I52	3.25	No	No	0	9	7
276	R:R:S179	R:R:T177	3.2	No	No	0	3	2
277	R:R:T141	R:R:T143	3.14	No	No	0	6	4
278	R:R:I164	R:R:S160	3.1	No	No	0	4	7
279	R:R:I110	R:R:V157	3.07	No	No	0	5	4
280	R:R:I124	R:R:V209	3.07	No	No	0	7	6
281	R:R:I200	R:R:V199	3.07	Yes	No	0	5	5
282	R:R:I296	R:R:V243	3.07	No	No	0	8	6
283	L:L:I63	L:L:V40	3.07	No	Yes	0	0	0
284	R:R:K22	R:R:V25	3.04	Yes	No	0	3	1
285	R:R:M241	R:R:V211	3.04	No	No	0	8	4
286	L:L:I25	L:L:T44	3.04	No	No	0	0	0
287	R:R:F109	R:R:G163	3.01	No	No	0	5	4
288	R:R:G301	R:R:R305	3	No	No	0	8	8
289	R:R:N24	R:R:V25	2.96	No	No	0	1	1
290	R:R:L36	R:R:T284	2.95	No	No	0	6	6
291	R:R:I292	R:R:I295	2.94	No	No	0	6	6
292	R:R:G216	R:R:Y127	2.9	No	No	0	4	8
293	R:R:Q186	R:R:S185	2.89	No	No	0	3	3
294	L:L:P19	L:L:R18	2.88	No	No	0	0	0
295	R:R:I200	R:R:L201	2.85	Yes	No	0	5	4
296	R:R:I217	R:R:L221	2.85	No	No	0	8	8
297	L:L:I16	L:L:L20	2.85	No	No	0	0	0
298	L:L:E27	L:L:V43	2.85	No	No	0	0	0
299	R:R:L50	R:R:M49	2.83	No	No	0	6	3
300	R:R:A156	R:R:F117	2.77	No	Yes	0	7	5
301	R:R:A136	R:R:R140	2.77	No	Yes	0	5	6
302	R:R:L203	R:R:L207	2.77	No	No	0	8	6
303	R:R:A298	R:R:F304	2.77	No	Yes	0	7	8
304	R:R:L53	R:R:N57	2.75	No	No	0	4	4
305	R:R:I23	R:R:Q27	2.74	No	No	0	3	2
306	L:L:C12	L:L:Y15	2.69	No	No	0	0	0
307	R:R:A87	R:R:Y37	2.67	No	Yes	0	6	8
308	L:L:Q49	R:R:L174	2.66	Yes	No	0	0	4
309	R:R:E262	R:R:N267	2.63	No	No	0	3	3
310	R:R:F158	R:R:V157	2.62	No	No	0	4	4
311	L:L:R48	L:L:V50	2.62	Yes	No	0	0	0
312	R:R:E18	R:R:Q21	2.55	Yes	No	0	3	1
313	L:L:Q49	R:R:E18	2.55	Yes	Yes	0	0	3
314	R:R:I28	R:R:R31	2.51	No	No	0	2	3
315	R:R:F135	R:R:K138	2.48	No	No	0	5	3
316	R:R:F311	R:R:K314	2.48	Yes	No	0	4	6
317	R:R:E227	R:R:H231	2.46	No	No	0	3	5
318	R:R:F45	R:R:L77	2.44	Yes	No	0	6	7
319	R:R:T82	R:R:W86	2.43	No	Yes	0	7	7
320	R:R:I67	R:R:Y68	2.42	No	Yes	0	7	7
321	R:R:N98	R:R:R168	2.41	No	No	0	3	4
322	R:R:K303	R:R:Y307	2.39	No	No	0	6	5
323	L:L:I16	L:L:W58	2.35	No	Yes	0	0	0
324	L:L:N37	L:L:Y15	2.33	No	No	0	0	0
325	R:R:D95	R:R:Y176	2.3	No	No	0	3	4
326	R:R:G202	R:R:P206	2.03	No	Yes	0	6	9
327	R:R:C291	R:R:G44	1.96	No	No	0	8	8
328	R:R:G216	R:R:S215	1.86	No	No	0	4	3
329	R:R:A30	R:R:A90	1.79	No	No	0	4	5
330	R:R:G216	R:R:K219	1.74	No	No	0	4	3
331	R:R:G47	R:R:L50	1.71	No	No	0	8	6
332	R:R:G286	R:R:L285	1.71	No	No	0	8	8
333	R:R:A278	R:R:V254	1.7	No	No	0	6	5
334	L:L:C35	L:L:T31	1.69	No	No	0	0	0
335	R:R:K197	R:R:P162	1.67	Yes	No	0	3	8
336	R:R:L36	R:R:P35	1.64	No	No	0	6	5
337	R:R:L161	R:R:P162	1.64	No	No	0	4	8
338	R:R:E172	R:R:G173	1.64	No	No	0	2	1
339	L:L:E27	R:R:G173	1.64	No	No	0	0	1
340	R:R:S149	R:R:V146	1.62	No	No	0	7	4
341	R:R:S149	R:R:V150	1.62	No	No	0	7	4
342	R:R:A249	R:R:I253	1.62	No	No	0	6	6
343	R:R:A159	R:R:K197	1.61	No	Yes	0	5	3
344	R:R:V142	R:R:V146	1.6	No	No	0	2	4
345	R:R:V146	R:R:V147	1.6	No	No	0	4	1
346	R:R:A298	R:R:L69	1.58	No	No	0	7	8
347	R:R:A233	R:R:L221	1.58	No	No	0	8	8
348	R:R:I42	R:R:S38	1.55	No	No	0	5	3
349	R:R:I151	R:R:V155	1.54	No	No	0	3	4
350	R:R:A92	R:R:Q93	1.52	No	No	0	4	3
351	L:L:K26	L:L:V43	1.52	No	No	0	0	0
352	R:R:G301	R:R:R232	1.5	No	No	0	8	7
353	L:L:A23	L:L:H24	1.46	No	No	0	0	0
354	R:R:I200	R:R:L196	1.43	Yes	No	0	5	4
355	L:L:I63	L:L:N64	1.42	No	No	0	0	0
356	R:R:R274	R:R:S270	1.32	No	No	0	2	1
357	R:R:D95	R:R:Q93	1.31	No	No	0	3	3
358	R:R:F117	R:R:V155	1.31	Yes	No	0	5	4
359	R:R:R230	R:R:V234	1.31	No	No	0	7	6
360	R:R:F144	R:R:T141	1.3	No	No	0	3	6
361	R:R:R235	R:R:T239	1.29	No	No	0	5	5
362	R:R:F45	R:R:L81	1.22	Yes	No	0	6	5
363	R:R:N306	R:R:R305	1.21	No	No	0	5	8
364	R:R:F135	R:R:H132	1.13	No	No	0	5	6
365	L:L:E67	L:L:Y28	1.12	No	Yes	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:E18	4.2	4	0	3
2	R:R:K22	6.55	4	1	3
3	R:R:Y37	4.885	4	5	8
4	R:R:F45	4.26	4	0	6
5	R:R:M64	5.5525	4	2	6
6	R:R:Y68	4.90167	6	2	7
7	R:R:F79	8.16	4	0	7
8	R:R:W86	7.76429	7	1	7
9	R:R:Y89	7.52	5	1	4
10	R:R:W94	12.212	5	1	9
11	R:R:F96	8.715	4	0	7
12	R:R:T105	5.9425	4	1	5
13	R:R:F117	3.9	5	8	5
14	R:R:F118	8.66	4	6	7
15	R:R:D125	7.41	4	2	8
16	R:R:R140	7.6875	4	0	6
17	R:R:F166	7.886	5	4	5
18	R:R:S169	4.36	4	1	4
19	R:R:C178	9.3575	4	1	9
20	R:R:F182	5.8875	4	4	5
21	R:R:Y187	8.51	4	0	3
22	R:R:W190	8.43667	6	4	3
23	R:R:K197	4.065	4	0	3
24	R:R:I200	2.99	4	0	5
25	R:R:P206	4.26	4	0	9
26	R:R:Y214	6.334	5	0	9
27	R:R:W248	7.932	5	7	9
28	R:R:Y251	9.6625	4	0	7
29	R:R:L255	8.5775	4	0	6
30	R:R:Q261	5.095	4	11	4
31	R:R:M287	6.466	5	5	8
32	R:R:Y297	5.955	4	0	9
33	R:R:F304	5.67	6	0	8
34	R:R:F311	4.13	4	0	4
35	L:L:?1	8.352	5	0	0
36	L:L:D6	7.965	4	1	0
37	L:L:I7	4.6175	4	1	0
38	L:L:V8	8.12	4	1	0
39	L:L:Y28	4.3325	4	12	0
40	L:L:V40	4.6025	4	12	0
41	L:L:R48	7.095	4	0	0
42	L:L:Q49	4.785	4	10	0
43	L:L:N53	5.99	4	0	0
44	L:L:W58	10.106	5	3	0
45	L:L:Y62	8.135	4	3	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:R48	R:R:E18	12.5923	6.98	Yes	Yes	0	0	3
2	L:L:K46	L:L:R48	15.345	13.61	No	Yes	0	0	0
3	L:L:K46	L:L:T44	16.2696	9.01	No	No	0	0	0
4	L:L:I25	L:L:T44	19.9154	3.04	No	No	0	0	0
5	L:L:F42	L:L:I25	20.8137	5.02	No	No	0	0	0
6	L:L:F42	L:L:V40	21.5124	5.24	No	Yes	12	0	0
7	L:L:V40	L:L:Y30	27.7455	5.05	Yes	No	0	0	0
8	L:L:Y30	R:R:H181	28.5493	4.36	No	No	0	0	4
9	R:R:H181	R:R:R168	29.3294	10.16	No	No	9	4	4
10	R:R:N98	R:R:R168	31.0893	2.41	No	No	0	3	4
11	R:R:N98	R:R:S169	12.6973	4.47	No	Yes	0	3	4
12	R:R:S169	R:R:W94	17.5567	4.94	Yes	Yes	1	4	9
13	R:R:W94	R:R:Y89	14.5413	9.65	Yes	Yes	1	9	4
14	L:L:D6	R:R:Y89	18.5443	9.2	Yes	Yes	1	0	4
15	L:L:D6	R:R:K26	17.5672	13.83	Yes	No	1	0	1
16	L:L:D6	R:R:A30	18.1424	4.63	Yes	No	0	0	4
17	R:R:A30	R:R:A90	16.5191	1.79	No	No	0	4	5
18	R:R:A90	R:R:P34	14.8906	5.61	No	No	0	5	6
19	R:R:P34	R:R:P35	13.2568	5.84	No	No	0	6	5
20	R:R:L36	R:R:P35	11.6178	1.64	No	No	0	6	5
21	R:R:N98	R:R:Q102	26.4164	7.92	No	No	0	3	7
22	R:R:Q102	R:R:T167	27.0101	4.25	No	No	0	7	5
23	R:R:T105	R:R:T167	27.0442	10.99	Yes	No	0	5	5
24	R:R:F109	R:R:T105	34.0732	3.89	No	Yes	0	5	5
25	R:R:F109	R:R:Y108	33.0278	8.25	No	No	0	5	7
26	R:R:F79	R:R:Y108	86.0681	12.38	Yes	No	0	7	7
27	R:R:F79	R:R:M287	62.1838	3.73	Yes	Yes	0	7	8
28	R:R:M287	R:R:V83	21.5571	7.61	Yes	No	5	8	7
29	R:R:P84	R:R:V83	21.3076	3.53	No	No	0	9	7
30	R:R:F41	R:R:P84	19.918	11.56	No	No	0	7	9
31	R:R:M287	R:R:V40	37.6954	9.13	Yes	No	0	8	7
32	R:R:C291	R:R:V40	36.3006	3.42	No	No	0	8	7
33	R:R:F41	R:R:F45	12.8917	9.65	No	Yes	0	7	6
34	R:R:C291	R:R:I292	33.4953	4.91	No	No	0	8	6
35	R:R:I292	R:R:I295	32.0848	2.94	No	No	0	6	6
36	R:R:F299	R:R:I295	30.669	6.28	No	No	0	7	6
37	R:R:F299	R:R:F304	27.8716	6.43	No	Yes	0	7	8
38	R:R:F304	R:R:I54	13.4328	8.79	Yes	No	0	8	7
39	R:R:F311	R:R:I54	12.0013	5.02	Yes	No	0	4	7
40	R:R:T105	R:R:W86	10.3307	3.64	Yes	Yes	1	5	7
41	R:R:W86	R:R:Y89	26.3692	8.68	Yes	Yes	1	7	4
42	R:R:C178	R:R:W94	10.856	19.59	Yes	Yes	1	9	9
43	R:R:C178	R:R:W86	18.5968	6.53	Yes	Yes	1	9	7
44	R:R:S180	R:R:T167	30.5009	4.8	No	No	0	4	5
45	R:R:F166	R:R:S180	30.388	3.96	Yes	No	0	5	4
46	R:R:F166	R:R:F182	14.8328	4.29	Yes	Yes	4	5	5
47	R:R:F182	R:R:Q194	25.1661	7.03	Yes	No	0	5	5
48	R:R:K197	R:R:Q194	100	6.78	Yes	No	0	3	5
49	R:R:F113	R:R:K197	96.2596	6.2	No	Yes	0	7	3
50	R:R:F113	R:R:F117	89.4802	5.36	No	Yes	8	7	5
51	R:R:F117	R:R:T152	86.5409	5.19	Yes	No	0	5	6
52	R:R:L121	R:R:T152	65.5276	4.42	No	No	0	6	6
53	R:R:L121	R:R:Y68	59.4416	5.86	No	Yes	2	6	7
54	R:R:D125	R:R:Y68	54.9211	3.45	Yes	Yes	2	8	7
55	R:R:D125	R:R:T65	48.4831	10.12	Yes	No	0	8	8
56	R:R:L122	R:R:T65	47.3011	4.42	No	No	0	9	8
57	R:R:F118	R:R:T152	25.3001	5.19	Yes	No	0	7	6
58	R:R:L122	R:R:Y297	46.0928	8.21	No	Yes	0	9	9
59	R:R:F118	R:R:S114	14.8486	7.93	Yes	No	6	7	7
60	R:R:S114	R:R:S75	13.551	6.52	No	No	0	7	8
61	R:R:G111	R:R:S75	10.8823	3.71	No	No	0	8	8
62	R:R:F112	R:R:F79	23.3642	5.36	No	Yes	0	7	7
63	L:L:P3	R:R:T105	23.0254	5.25	No	Yes	1	0	5
64	L:L:P4	R:R:W86	42.3446	16.21	No	Yes	0	0	7
65	R:R:K171	R:R:S169	16.3248	4.59	No	Yes	0	2	4
66	R:R:K171	R:R:Y176	11.6861	4.78	No	No	0	2	4
67	R:R:F112	R:R:W248	21.9432	7.02	No	Yes	0	7	9
68	R:R:W248	R:R:Y244	10.3675	8.68	Yes	No	7	9	9
69	R:R:R126	R:R:Y297	38.8774	6.17	No	Yes	0	9	9
70	R:R:R126	R:R:Y214	37.6455	6.17	No	Yes	0	9	9
71	R:R:T123	R:R:Y214	21.473	6.24	No	Yes	0	9	9
72	R:R:C213	R:R:T123	18.8621	3.38	No	No	0	8	9
73	R:R:C213	R:R:Y127	17.5488	6.72	No	No	0	8	8
74	R:R:V131	R:R:Y127	12.2429	12.62	No	No	0	7	8
75	R:R:F166	R:R:W190	15.2005	11.02	Yes	Yes	4	5	3
76	L:L:?1	L:L:K34	10.7142	10.56	Yes	No	0	0	0
77	L:L:?1	L:L:G2	73.6256	7.32	Yes	No	0	0	0
78	L:L:G2	L:L:P3	73.9198	4.06	No	No	0	0	0
79	L:L:E55	R:R:S185	21.5124	4.31	No	No	0	0	3
80	R:R:Q186	R:R:S185	22.3635	2.89	No	No	0	3	3
81	R:R:Q186	R:R:W190	23.1961	5.48	No	Yes	0	3	3
82	L:L:E55	L:L:N53	18.9567	3.94	No	Yes	0	0	0
83	L:L:?1	R:R:L255	34.9584	8.88	Yes	Yes	0	0	6
84	L:L:P4	R:R:E283	34.5696	4.72	No	No	0	0	6
85	R:R:E283	R:R:Y251	34.173	12.35	No	Yes	0	6	7
86	R:R:L255	R:R:M279	18.1477	5.65	Yes	No	0	6	5
87	R:R:M279	R:R:N258	14.6017	4.21	No	No	0	5	4
88	L:L:K56	L:L:N53	12.0459	4.2	No	Yes	0	0	0
89	L:L:D6	L:L:I7	15.064	4.2	Yes	Yes	1	0	0
90	L:L:I7	R:R:W86	16.372	4.7	Yes	Yes	1	0	7
91	L:L:P3	R:R:W86	51.3015	12.16	No	Yes	1	0	7
92	L:L:?1	R:R:Q194	87.0742	7.12	Yes	No	0	0	5
93	L:L:P4	R:R:Y108	54.4798	16.69	No	No	0	0	7
94	R:R:L255	R:R:Y251	30.5088	14.07	Yes	Yes	0	6	7
95	R:R:F182	R:R:W190	10.7405	5.01	Yes	Yes	4	5	3

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:R48	R:R:T16	5.17	0	Yes	No	0	2	0	1
R:R:E18	R:R:P19	4.72	0	Yes	No	3	4	1	2
L:L:R48	R:R:E18	6.98	0	Yes	Yes	0	3	0	1
R:R:K22	R:R:K26	7.18	1	Yes	No	3	1	1	1
R:R:K22	R:R:N273	8.39	1	Yes	No	3	1	1	2
L:L:V8	R:R:K22	7.59	1	Yes	Yes	0	3	0	1
L:L:D6	R:R:K26	13.83	1	Yes	No	0	1	0	1
L:L:V8	R:R:K26	4.55	1	Yes	No	0	1	0	1
R:R:A29	R:R:Q280	4.55	0	No	No	5	3	2	1
L:L:D6	R:R:A30	4.63	1	Yes	No	0	4	0	1
R:R:L33	R:R:Q280	3.99	0	No	No	6	3	2	1
R:R:F79	R:R:Y108	12.38	0	Yes	No	7	7	2	1
R:R:W86	R:R:Y89	8.68	1	Yes	Yes	7	4	1	1
R:R:T105	R:R:W86	3.64	1	Yes	Yes	5	7	1	1
R:R:C178	R:R:W86	6.53	1	Yes	Yes	9	7	2	1
L:L:P3	R:R:W86	12.16	1	No	Yes	0	7	0	1
L:L:P4	R:R:W86	16.21	0	No	Yes	0	7	0	1
L:L:I7	R:R:W86	4.7	1	Yes	Yes	0	7	0	1
R:R:W94	R:R:Y89	9.65	1	Yes	Yes	9	4	2	1
R:R:C178	R:R:Y89	4.03	1	Yes	Yes	9	4	2	1
L:L:D6	R:R:Y89	9.2	1	Yes	Yes	0	4	0	1
L:L:I7	R:R:Y89	6.04	1	Yes	Yes	0	4	0	1
R:R:C178	R:R:W94	19.59	1	Yes	Yes	9	9	2	2
R:R:F109	R:R:T105	3.89	0	No	Yes	5	5	2	1
R:R:T105	R:R:T167	10.99	1	Yes	No	5	5	1	2
L:L:P3	R:R:T105	5.25	1	No	Yes	0	5	0	1
R:R:F109	R:R:Y108	8.25	0	No	No	5	7	2	1
L:L:P4	R:R:Y108	16.69	0	No	No	0	7	0	1
R:R:Q170	R:R:R168	8.18	9	No	No	1	4	2	2
R:R:H181	R:R:R168	10.16	9	No	No	4	4	1	2
R:R:H181	R:R:Q170	7.42	9	No	No	4	1	1	2
L:L:F29	R:R:E172	22.15	10	No	No	0	2	0	1
L:L:L9	R:R:T177	5.9	0	No	No	0	2	0	1
L:L:Y30	R:R:H181	4.36	0	No	No	0	4	0	1
R:R:F182	R:R:Y187	7.22	4	Yes	Yes	5	3	2	1
R:R:F182	R:R:Q194	7.03	4	Yes	No	5	5	2	1
L:L:P54	R:R:Y184	9.74	0	No	No	0	1	0	1
L:L:E55	R:R:Y184	6.73	0	No	No	0	1	0	1
L:L:E55	R:R:S185	4.31	0	No	No	0	3	0	1
R:R:K191	R:R:Y187	7.17	0	No	Yes	4	3	2	1
L:L:G33	R:R:Y187	4.35	0	No	Yes	0	3	0	1
L:L:P38	R:R:Y187	15.3	0	No	Yes	0	3	0	1
R:R:K197	R:R:Q194	6.78	0	Yes	No	3	5	2	1
L:L:?1	R:R:Q194	7.12	0	Yes	No	0	5	0	1
R:R:T195	R:R:T259	12.56	0	No	No	5	5	1	2
L:L:?1	R:R:T195	7.88	0	Yes	No	0	5	0	1
R:R:I198	R:R:L255	5.71	0	No	Yes	5	6	2	1
R:R:L255	R:R:Y251	14.07	0	Yes	Yes	6	7	1	2
R:R:E283	R:R:Y251	12.35	0	No	Yes	6	7	1	2
R:R:L255	R:R:M279	5.65	0	Yes	No	6	5	1	2
L:L:?1	R:R:L255	8.88	0	Yes	Yes	0	6	0	1
R:R:Q261	R:R:S272	5.78	11	Yes	No	4	3	2	1
L:L:F13	R:R:S272	3.96	0	No	No	0	3	0	1
L:L:V8	R:R:D276	14.61	1	Yes	No	0	4	0	1
L:L:V8	R:R:Q280	5.73	1	Yes	No	0	3	0	1
L:L:P4	R:R:E283	4.72	0	No	No	0	6	0	1
L:L:S32	R:R:S179	3.26	0	No	No	0	3	0	1
R:R:S179	R:R:T177	3.2	0	No	No	3	2	1	1
R:R:K22	R:R:V25	3.04	1	Yes	No	3	1	1	2
R:R:Q186	R:R:S185	2.89	0	No	No	3	3	2	1
L:L:Q49	R:R:L174	2.66	10	Yes	No	0	4	0	1
R:R:E18	R:R:Q21	2.55	0	Yes	No	3	1	1	2
L:L:Q49	R:R:E18	2.55	10	Yes	Yes	0	3	0	1
R:R:T82	R:R:W86	2.43	0	No	Yes	7	7	2	1
R:R:A30	R:R:A90	1.79	0	No	No	4	5	1	2
R:R:E172	R:R:G173	1.64	0	No	No	2	1	1	1
L:L:E27	R:R:G173	1.64	0	No	No	0	1	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7O7F_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.38
Number of Linked Nodes	339
Number of Links	365
Number of Hubs	45
Number of Links mediated by Hubs	169
Number of Communities	12
Number of Nodes involved in Communities	52
Number of Links involved in Communities	63

Path Summary
Number Of Nodes in MetaPath	96
Number Of Links MetaPath	95
Number of Shortest Paths	83863
Length Of Smallest Path	3
Average Path Length	17.4638
Length of Longest Path	46
Minimum Path Strength	1.415
Average Path Strength	6.71026
Maximum Path Strength	19.315
Minimum Path Correlation	0.7
Average Path Correlation	0.94697
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.63158
Average % Of Corr. Nodes	56.5699
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.8646
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • protein-containing complex binding • binding • protein binding • enzyme binding • GTPase binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • virus receptor activity • exogenous protein binding • molecular transducer activity • coreceptor activity • signaling receptor activity • phosphoric ester hydrolase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • phospholipase C activity • phosphatidylinositol-4,5-bisphosphate phospholipase C activity • phospholipase activity • lipase activity • G protein-coupled chemoattractant receptor activity • C-C chemokine receptor activity • chemokine receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • cytokine receptor activity • immune receptor activity • cytoskeletal protein binding • actin binding • C-C chemokine binding • chemokine binding • cytokine binding • chemokine (C-C motif) ligand 5 binding • identical protein binding • leukocyte apoptotic process • negative regulation of biological process • regulation of programmed cell death • macrophage apoptotic process • negative regulation of leukocyte apoptotic process • negative regulation of cellular process • myeloid cell apoptotic process • regulation of leukocyte apoptotic process • negative regulation of programmed cell death • regulation of apoptotic process • negative regulation of macrophage apoptotic process • cell death • negative regulation of apoptotic process • regulation of macrophage apoptotic process • inflammatory cell apoptotic process • negative regulation of myeloid cell apoptotic process • apoptotic process • regulation of myeloid cell apoptotic process • programmed cell death • positive regulation of cytosolic calcium ion concentration • regulation of biological quality • immune response • immune system process • response to sterol • response to cholesterol • cell-cell signaling • biological process involved in interspecies interaction between organisms • response to other organism • cellular response to lipopolysaccharide • response to external stimulus • cellular response to molecule of bacterial origin • response to lipopolysaccharide • response to biotic stimulus • cellular response to biotic stimulus • response to bacterium • response to external biotic stimulus • response to molecule of bacterial origin • intracellular signal transduction • calcium-mediated signaling • intracellular signaling cassette • MAPK cascade • chemotaxis • taxis • locomotion • cell chemotaxis • dendritic cell chemotaxis • leukocyte migration • dendritic cell migration • mononuclear cell migration • cell migration • cell motility • leukocyte chemotaxis • cell surface receptor signaling pathway • defense response • response to stress • cellular defense response • localization • transport • monoatomic ion transport • monoatomic cation transport • establishment of localization • calcium ion transport • metal ion transport • inflammatory response • regulation of localization • cellular localization • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • monoatomic ion transmembrane transport • sarcoplasmic reticulum calcium ion transport • calcium ion homeostasis • release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • negative regulation of sequestering of calcium ion • maintenance of location in cell • monoatomic cation transmembrane transport • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • regulation of sequestering of calcium ion • intracellular monoatomic ion homeostasis • release of sequestered calcium ion into cytosol by endoplasmic reticulum • calcium ion transmembrane import into cytosol • sequestering of calcium ion • inorganic ion transmembrane transport • inorganic cation transmembrane transport • maintenance of location • transmembrane transport • release of sequestered calcium ion into cytosol • cellular homeostasis • chemical homeostasis • calcium ion transmembrane transport • cell surface • external side of plasma membrane • endosome • intracellular vesicle • cytoplasmic vesicle • G-protein beta-subunit binding • protein localization • cellular macromolecule localization • macromolecule localization • cellular developmental process • photoreceptor cell differentiation • cell development • eye morphogenesis • neurogenesis • neuron differentiation • cell differentiation • eye photoreceptor cell differentiation • animal organ morphogenesis • photoreceptor cell development • eye photoreceptor cell development • nervous system development • generation of neurons • anatomical structure morphogenesis • sensory organ morphogenesis • neuron development • phototransduction • detection of light stimulus • response to light stimulus • detection of external stimulus • detection of abiotic stimulus • detection of stimulus • response to abiotic stimulus • response to radiation • CCR5 chemokine receptor binding • CCR chemokine receptor binding • signaling receptor binding • cytokine receptor binding • G protein-coupled receptor binding • chemokine receptor binding • protein tyrosine kinase activator activity • enzyme regulator activity • receptor signaling protein tyrosine kinase activator activity • catalytic activity, acting on a protein • molecular function activator activity • kinase activity • protein kinase activity • transferase activity • protein kinase regulator activity • phosphotransferase activity, alcohol group as acceptor • transferase activity, transferring phosphorus-containing groups • kinase activator activity • enzyme activator activity • protein tyrosine kinase activity • molecular function regulator activity • protein kinase activator activity • kinase regulator activity • signaling receptor activator activity • chemokine activity • cytokine activity • signaling receptor regulator activity • receptor ligand activity • CCR4 chemokine receptor binding • CCR1 chemokine receptor binding • protein homodimerization activity • protein dimerization activity • chemoattractant activity • phospholipase activator activity • lipase activator activity • signaling receptor inhibitor activity • receptor antagonist activity • molecular function inhibitor activity • chemokine receptor antagonist activity • positive regulation of cell communication • regulation of signaling • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • positive regulation of G protein-coupled receptor signaling pathway • positive regulation of response to stimulus • regulation of response to stimulus • regulation of cell communication • regulation of G protein-coupled receptor signaling pathway • positive regulation of cellular process • positive regulation of signaling • positive regulation of locomotion • regulation of cell motility • positive regulation of chemotaxis • positive regulation of cell migration • regulation of lymphocyte chemotaxis • natural killer cell chemotaxis • positive regulation of natural killer cell chemotaxis • regulation of immune system process • regulation of mononuclear cell migration • positive regulation of immune system process • regulation of leukocyte chemotaxis • positive regulation of lymphocyte migration • regulation of leukocyte migration • lymphocyte migration • positive regulation of leukocyte chemotaxis • regulation of locomotion • regulation of natural killer cell chemotaxis • regulation of response to external stimulus • lymphocyte chemotaxis • regulation of lymphocyte migration • positive regulation of lymphocyte chemotaxis • positive regulation of response to external stimulus • positive regulation of cell motility • regulation of cell migration • positive regulation of mononuclear cell migration • positive regulation of leukocyte migration • regulation of chemotaxis • cell surface receptor signaling pathway via STAT • regulation of intracellular signal transduction • positive regulation of TOR signaling • TOR signaling • regulation of TOR signaling • positive regulation of intracellular signal transduction • response to toxic substance • positive regulation of smooth muscle cell migration • regulation of smooth muscle cell migration • smooth muscle cell migration • muscle cell migration • response to fibroblast growth factor • cellular response to growth factor stimulus • response to growth factor • cellular response to fibroblast growth factor stimulus • macrophage migration • positive regulation of macrophage migration • granulocyte migration • macrophage chemotaxis • regulation of granulocyte chemotaxis • regulation of macrophage migration • myeloid leukocyte migration • regulation of macrophage chemotaxis • granulocyte chemotaxis • positive regulation of macrophage chemotaxis • establishment of protein localization • nitrogen compound transport • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • regulation of protein secretion • regulation of secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • hormone transport • insulin secretion • regulation of leukocyte activation • cell activation • regulation of cell activation • regulation of T cell activation • lymphocyte activation • leukocyte activation • T cell activation • regulation of multicellular organismal process • regulation of lymphocyte activation • positive regulation of monocyte chemotaxis • regulation of monocyte chemotaxis • monocyte chemotaxis • positive regulation of viral genome replication • positive regulation of viral process • viral life cycle • regulation of viral life cycle • regulation of viral process • viral genome replication • viral process • regulation of viral genome replication • regulation of calcium ion transport • positive regulation of calcium ion transport • regulation of monoatomic ion transport • positive regulation of transport • positive regulation of monoatomic ion transport • regulation of metal ion transport • positive regulation of T cell migration • regulation of T cell migration • T cell migration • regulation of smooth muscle cell proliferation • positive regulation of cell population proliferation • smooth muscle cell proliferation • positive regulation of smooth muscle cell proliferation • regulation of cell population proliferation • muscle cell proliferation • cell adhesion • cell-cell adhesion • leukocyte cell-cell adhesion • eosinophil chemotaxis • eosinophil migration • regulation of homotypic cell-cell adhesion • positive regulation of cell adhesion • regulation of cell adhesion • homotypic cell-cell adhesion • positive regulation of cell-cell adhesion • positive regulation of homotypic cell-cell adhesion • regulation of cell-cell adhesion • regulation of lymphocyte apoptotic process • negative regulation of T cell apoptotic process • lymphocyte apoptotic process • regulation of T cell apoptotic process • T cell apoptotic process • negative regulation of lymphocyte apoptotic process • positive regulation of protein metabolic process • positive regulation of translation • positive regulation of macromolecule biosynthetic process • regulation of primary metabolic process • post-transcriptional regulation of gene expression • positive regulation of metabolic process • positive regulation of biosynthetic process • positive regulation of macromolecule metabolic process • translational initiation • protein metabolic process • regulation of biosynthetic process • regulation of translational initiation • regulation of protein metabolic process • primary metabolic process • regulation of macromolecule metabolic process • gene expression • translation • macromolecule biosynthetic process • regulation of gene expression • biosynthetic process • positive regulation of gene expression • regulation of translation • regulation of macromolecule biosynthetic process • metabolic process • positive regulation of translational initiation • macromolecule metabolic process • regulation of metabolic process • positive regulation of programmed cell death • positive regulation of lymphocyte apoptotic process • positive regulation of apoptotic process • positive regulation of T cell apoptotic process • positive regulation of leukocyte apoptotic process • positive regulation of cell activation • lymphocyte proliferation • positive regulation of leukocyte activation • regulation of leukocyte proliferation • positive regulation of T cell activation • positive regulation of lymphocyte proliferation • positive regulation of T cell proliferation • mononuclear cell proliferation • regulation of leukocyte cell-cell adhesion • positive regulation of leukocyte proliferation • positive regulation of multicellular organismal process • positive regulation of leukocyte cell-cell adhesion • leukocyte proliferation • positive regulation of lymphocyte activation • positive regulation of mononuclear cell proliferation • T cell proliferation • regulation of lymphocyte proliferation • regulation of T cell proliferation • regulation of mononuclear cell proliferation • response to peptide • cellular response to interleukin-1 • response to cytokine • cellular response to cytokine stimulus • response to interleukin-1 • viral gene expression • negative regulation by host of viral transcription • modulation of process of another organism • viral transcription • host-mediated perturbation of symbiont process • positive regulation of receptor signaling pathway via STAT • regulation of receptor signaling pathway via STAT • cell-cell adhesion mediated by integrin • positive regulation of cell adhesion mediated by integrin • regulation of cell adhesion mediated by integrin • regulation of cell-cell adhesion mediated by integrin • positive regulation of cell-cell adhesion mediated by integrin • cell adhesion mediated by integrin • neutrophil activation • myeloid leukocyte activation • granulocyte activation • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • positive regulation of epithelial cell proliferation • regulation of epithelial cell proliferation • epithelial cell proliferation • regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction • phosphatidylinositol 3-kinase/protein kinase B signal transduction • regulation of defense response • regulation of chronic inflammatory response • chronic inflammatory response • regulation of inflammatory response • regulation of response to stress • cellular response to tumor necrosis factor • response to tumor necrosis factor • response to type II interferon • defense response to symbiont • cellular response to type II interferon • defense response to other organism • innate immune response • humoral immune response • antimicrobial humoral response • antimicrobial humoral immune response mediated by antimicrobial peptide • negative regulation of viral genome replication • negative regulation of viral process • response to virus • positive regulation of T cell chemotaxis • regulation of T cell chemotaxis • T cell chemotaxis • regulation of phospholipase activity • positive regulation of phospholipase activity • regulation of catalytic activity • activation of phospholipase D activity • positive regulation of catalytic activity • positive regulation of lipase activity • regulation of molecular function • positive regulation of molecular function • positive regulation of hydrolase activity • regulation of hydrolase activity • negative regulation of signaling • negative regulation of response to stimulus • negative regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • negative regulation of cell communication • exocytosis • vesicle-mediated transport • positive regulation of response to biotic stimulus • regulation of response to biotic stimulus • positive regulation of immune response • positive regulation of innate immune response • regulation of innate immune response • positive regulation of defense response • regulation of immune response • cellular response to virus • chemokine (C-C motif) ligand 5 signaling pathway
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • WD40 repeat-like • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Interleukin 8-like chemokines
SCOP2	Family Identifier	• Ras-like P-loop GTPases • WD40 repeat-like • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain • Interleukin 8-like chemokines
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	PCA
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	PCA
Name	Pidolic acid
Synonyms	5-Pyrrolidone-2-carboxylic acid
Identifier
Formula	C5 H7 N O3
Molecular Weight	129.114
SMILES
PubChem	7405
Formal Charge	0
Total Atoms	16
Total Chiral Atoms	1
Total Bonds	16
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P51681
Sequence	>7O7F_nogp_Chain_R T S E P C Q K I N V K Q I A A R L L P P L Y S L V F I F G F V G N M L V I L I L I N C K R L K S M T D I Y L L N L A I S D L F F L L T V P F W A H Y A A A Q W D F G N T M C Q L L T G L Y F I G F F S G I F F I I L L T I D R Y L A V V H A V F A L K A R T V T F G V V T S V I T W V V A V F A S L P G I I F T R S Q K E G L H Y T C S S H F P Y S Q Y Q F W K N F Q T L K I V I L G L V L P L L V M V I C Y S G I L K T L L R C R N E K K R H R A V R L I F T I M I V Y F L F W A P Y N I V L L L N T F Q E F F G L N N C S S S N R L D Q A M Q V T E T L G M T H C C I N P I I Y A F V G E K F R N Y L L V F F Q K H Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7F1T	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	-	2.6	2021-07-14	10.1038/s41467-021-24438-5
	7F1S	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	2.8	2021-07-14	10.1038/s41467-021-24438-5
	7F1S (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		2.8	2021-07-14	10.1038/s41467-021-24438-5
	7F1R	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/β1/γ2	3	2021-07-14	10.1038/s41467-021-24438-5
	7F1R (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	-	-		3	2021-07-14	10.1038/s41467-021-24438-5
	7F1Q	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	Gi1/β1/γ2	2.9	2021-07-14	10.1038/s41467-021-24438-5
	7F1Q (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-		2.9	2021-07-14	10.1038/s41467-021-24438-5
	7O7F	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-	Gi1/β1/γ1	3.15	2021-06-30	10.1126/sciadv.abg8685
	7O7F (No Gprot)	A	Protein	Chemokine	CCR5	Homo sapiens	6P4-CCL5	-		3.15	2021-06-30	10.1126/sciadv.abg8685
	6MET	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	4.5	2018-12-12	10.1038/s41586-018-0804-9
	6MEO	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	3.9	2018-12-12	10.1038/s41586-018-0804-9
	6AKY	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
	6AKX	A	Protein	Chemokine	CCR5	Homo sapiens	-	A4R	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
	5UIW	A	Protein	Chemokine	CCR5	Homo sapiens	5P7-CCL5	-	-	2.2	2017-06-28	10.1016/j.immuni.2017.05.002
	4MBS	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.71	2013-09-11	10.1126/science.1241475

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